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Erin K. O'Shea - Publications

Affiliations: 
Chemistry and Chemical Biology Harvard University, Cambridge, MA, United States 
Area:
signal transduction, transcriptional regulation
Website:
http://labs.mcb.harvard.edu/o%27shea/people/erin.html
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84 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 He BZ, Zhou X, O'Shea EK. Correction: Evolution of reduced co-activator dependence led to target expansion of a starvation response pathway. Elife. 11. PMID 36264273 DOI: 10.7554/eLife.84187  0.317
2018 Yu Z, Surface LE, Park CY, Horlbeck MA, Wyant GA, Abu-Remaileh M, Peterson TR, Sabatini DM, Weissman JS, O'Shea EK. Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing-bisphosphonates. Elife. 7. PMID 29745899 DOI: 10.7554/Elife.36620  0.492
2018 Yu Z, Surface LE, Park CY, Horlbeck MA, Wyant GA, Abu-Remaileh M, Peterson TR, Sabatini DM, Weissman JS, O'Shea EK. Author response: Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates Elife. DOI: 10.7554/Elife.36620.020  0.489
2017 Piechura JR, Amarnath K, O'Shea EK. Natural changes in light interact with circadian regulation at promoters to control gene expression in cyanobacteria. Elife. 6. PMID 29239721 DOI: 10.7554/eLife.32032  0.363
2017 Greider C, Hopkins N, Steitz J, Amon A, Asai D, Barres B, Bass B, Bassler B, Birgeneau R, Bjorkman P, Botchan M, Brugge J, Cech T, Colwell R, Craig N, et al. Not just Salk. Science (New York, N.Y.). 357: 1105-1106. PMID 28912235 DOI: 10.1126/Science.Aao6221  0.548
2017 Choi J, Rajagopal A, Xu YF, Rabinowitz JD, O'Shea EK. A systematic genetic screen for genes involved in sensing inorganic phosphate availability in Saccharomyces cerevisiae. Plos One. 12: e0176085. PMID 28520786 DOI: 10.1371/Journal.Pone.0176085  0.553
2017 He BZ, Zhou X, O'Shea EK. Evolution of reduced co-activator dependence led to target expansion of a starvation response pathway. Elife. 6. PMID 28485712 DOI: 10.7554/Elife.25157  0.409
2017 Puszynska AM, O'Shea EK. Switching of metabolic programs in response to light availability is an essential function of the cyanobacterial circadian output pathway. Elife. 6. PMID 28430105 DOI: 10.7554/eLife.23210  0.339
2016 Zhou X, Blocker AW, Airoldi EM, O'Shea EK. A computational approach to map nucleosome positions and alternative chromatin states with base pair resolution. Elife. 5. PMID 27623011 DOI: 10.7554/Elife.16970  0.441
2016 Zhou X, Blocker AW, Airoldi EM, O'Shea EK. Author response: A computational approach to map nucleosome positions and alternative chromatin states with base pair resolution Elife. DOI: 10.7554/Elife.16970.039  0.388
2015 Hansen AS, Hao N, O'Shea EK. High-throughput microfluidics to control and measure signaling dynamics in single yeast cells. Nature Protocols. 10: 1181-97. PMID 26158443 DOI: 10.1038/Nprot.2015.079  0.541
2015 Hansen AS, O'Shea EK. Limits on information transduction through amplitude and frequency regulation of transcription factor activity. Elife. 4. PMID 25985085 DOI: 10.7554/eLife.06559  0.382
2015 Hansen AS, O'Shea EK. Author response: Limits on information transduction through amplitude and frequency regulation of transcription factor activity Elife. DOI: 10.7554/Elife.06559.017  0.347
2014 Mukherji S, O'Shea EK. Mechanisms of organelle biogenesis govern stochastic fluctuations in organelle abundance. Elife. 3: e02678. PMID 24916159 DOI: 10.7554/eLife.02678.001  0.325
2013 Subramaniam AR, Deloughery A, Bradshaw N, Chen Y, O'Shea E, Losick R, Chai Y. A serine sensor for multicellularity in a bacterium Elife. 2013. PMID 24347549 DOI: 10.7554/Elife.01501  0.457
2013 Markson JS, Piechura JR, Puszynska AM, O'Shea EK. Circadian control of global gene expression by the cyanobacterial master regulator RpaA. Cell. 155: 1396-408. PMID 24315105 DOI: 10.1016/J.Cell.2013.11.005  0.805
2013 Teng SW, Mukherji S, Moffitt JR, de Buyl S, O'Shea EK. Robust circadian oscillations in growing cyanobacteria require transcriptional feedback. Science (New York, N.Y.). 340: 737-40. PMID 23661759 DOI: 10.1126/Science.1230996  0.595
2013 Gutu A, O'Shea EK. Two antagonistic clock-regulated histidine kinases time the activation of circadian gene expression. Molecular Cell. 50: 288-94. PMID 23541768 DOI: 10.1016/J.Molcel.2013.02.022  0.323
2013 Hao N, Budnik BA, Gunawardena J, O'Shea EK. Tunable signal processing through modular control of transcription factor translocation. Science (New York, N.Y.). 339: 460-4. PMID 23349292 DOI: 10.1126/Science.1227299  0.536
2013 Vijayan V, O'Shea EK. Sequence determinants of circadian gene expression phase in cyanobacteria. Journal of Bacteriology. 195: 665-71. PMID 23204469 DOI: 10.1128/Jb.02012-12  0.612
2012 Carter-O'Connell I, Peel MT, Wykoff DD, O'Shea EK. Genome-wide characterization of the phosphate starvation response in Schizosaccharomyces pombe. Bmc Genomics. 13: 697. PMID 23231582 DOI: 10.1186/1471-2164-13-697  0.805
2012 Cook KE, O'Shea EK. Hog1 controls global reallocation of RNA Pol II upon osmotic shock in Saccharomyces cerevisiae. G3 (Bethesda, Md.). 2: 1129-36. PMID 22973550 DOI: 10.1534/G3.112.003251  0.631
2012 Jain IH, Vijayan V, O'Shea EK. Spatial ordering of chromosomes enhances the fidelity of chromosome partitioning in cyanobacteria. Proceedings of the National Academy of Sciences of the United States of America. 109: 13638-43. PMID 22869746 DOI: 10.1073/Pnas.1211144109  0.497
2012 Hao N, O'Shea EK. Signal-dependent dynamics of transcription factor translocation controls gene expression. Nature Structural & Molecular Biology. 19: 31-9. PMID 22179789 DOI: 10.1038/Nsmb.2192  0.589
2011 Zhou X, O'Shea EK. Integrated approaches reveal determinants of genome-wide binding and function of the transcription factor Pho4. Molecular Cell. 42: 826-36. PMID 21700227 DOI: 10.1016/J.Molcel.2011.05.025  0.499
2011 Vijayan V, Jain IH, O'Shea EK. A high resolution map of a cyanobacterial transcriptome. Genome Biology. 12: R47. PMID 21612627 DOI: 10.1186/Gb-2011-12-5-R47  0.637
2009 Vijayan V, Zuzow R, O'Shea EK. Oscillations in supercoiling drive circadian gene expression in cyanobacteria. Proceedings of the National Academy of Sciences of the United States of America. 106: 22564-8. PMID 20018699 DOI: 10.1073/Pnas.0912673106  0.643
2009 Markson JS, O'Shea EK. The molecular clockwork of a protein-based circadian oscillator. Febs Letters. 583: 3938-47. PMID 19913541 DOI: 10.1016/J.Febslet.2009.11.021  0.772
2009 Kim HD, Shay T, O'Shea EK, Regev A. Transcriptional regulatory circuits: predicting numbers from alphabets. Science (New York, N.Y.). 325: 429-32. PMID 19628860 DOI: 10.1126/Science.1171347  0.494
2008 Capaldi AP, Kaplan T, Liu Y, Habib N, Regev A, Friedman N, O'Shea EK. Structure and function of a transcriptional network activated by the MAPK Hog1. Nature Genetics. 40: 1300-6. PMID 18931682 DOI: 10.1038/Ng.235  0.392
2008 Kim HD, O'Shea EK. A quantitative model of transcription factor-activated gene expression. Nature Structural & Molecular Biology. 15: 1192-8. PMID 18849996 DOI: 10.1038/Nsmb.1500  0.583
2008 Lam FH, Steger DJ, O'Shea EK. Chromatin decouples promoter threshold from dynamic range. Nature. 453: 246-50. PMID 18418379 DOI: 10.1038/nature06867  0.601
2008 Lee YS, Huang K, Quiocho FA, O'Shea EK. Molecular basis of cyclin-CDK-CKI regulation by reversible binding of an inositol pyrophosphate. Nature Chemical Biology. 4: 25-32. PMID 18059263 DOI: 10.1038/Nchembio.2007.52  0.419
2007 Huang K, Ferrin-O'Connell I, Zhang W, Leonard GA, O'Shea EK, Quiocho FA. Structure of the Pho85-Pho80 CDK-cyclin complex of the phosphate-responsive signal transduction pathway. Molecular Cell. 28: 614-23. PMID 18042456 DOI: 10.1016/J.Molcel.2007.09.013  0.434
2007 Rust MJ, Markson JS, Lane WS, Fisher DS, O'Shea EK. Ordered phosphorylation governs oscillation of a three-protein circadian clock. Science (New York, N.Y.). 318: 809-12. PMID 17916691 DOI: 10.1126/Science.1148596  0.781
2007 Wykoff DD, Rizvi AH, Raser JM, Margolin B, O'Shea EK. Positive feedback regulates switching of phosphate transporters in S. cerevisiae. Molecular Cell. 27: 1005-13. PMID 17889672 DOI: 10.1016/J.Molcel.2007.07.022  0.774
2007 Maheshri N, O'Shea EK. Living with noisy genes: how cells function reliably with inherent variability in gene expression. Annual Review of Biophysics and Biomolecular Structure. 36: 413-34. PMID 17477840 DOI: 10.1146/Annurev.Biophys.36.040306.132705  0.335
2007 Lee YS, Mulugu S, York JD, O'Shea EK. Regulation of a cyclin-CDK-CDK inhibitor complex by inositol pyrophosphates. Science (New York, N.Y.). 316: 109-12. PMID 17412959 DOI: 10.1126/Science.1139080  0.393
2006 Bar-Even A, Paulsson J, Maheshri N, Carmi M, O'Shea E, Pilpel Y, Barkai N. Noise in protein expression scales with natural protein abundance. Nature Genetics. 38: 636-43. PMID 16715097 DOI: 10.1038/Ng1807  0.411
2006 Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, et al. Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 440: 637-43. PMID 16554755 DOI: 10.1038/Nature04670  0.527
2005 Howson R, Huh WK, Ghaemmaghami S, Falvo JV, Bower K, Belle A, Dephoure N, Wykoff DD, Weissman JS, O'Shea EK. Construction, verification and experimental use of two epitope-tagged collections of budding yeast strains. Comparative and Functional Genomics. 6: 2-16. PMID 18629296 DOI: 10.1002/Cfg.449  0.764
2005 Dephoure N, Howson RW, Blethrow JD, Shokat KM, O'Shea EK. Combining chemical genetics and proteomics to identify protein kinase substrates. Proceedings of the National Academy of Sciences of the United States of America. 102: 17940-5. PMID 16330754 DOI: 10.1073/Pnas.0509080102  0.781
2005 Raser JM, O'Shea EK. Noise in gene expression: origins, consequences, and control. Science (New York, N.Y.). 309: 2010-3. PMID 16179466 DOI: 10.1126/Science.1105891  0.764
2005 Thomas MR, O'Shea EK. An intracellular phosphate buffer filters transient fluctuations in extracellular phosphate levels. Proceedings of the National Academy of Sciences of the United States of America. 102: 9565-70. PMID 15972809 DOI: 10.1073/pnas.0501122102  0.364
2005 Huang S, O'Shea EK. A systematic high-throughput screen of a yeast deletion collection for mutants defective in PHO5 regulation. Genetics. 169: 1859-71. PMID 15695358 DOI: 10.1534/Genetics.104.038695  0.614
2004 Weissman JS, O'Shea EK. 2004 Irving Sigal Young Investigator Award. Protein Science : a Publication of the Protein Society. 13: 3333-5. PMID 15557272 DOI: 10.1110/Ps.041134604  0.47
2004 Marion RM, Regev A, Segal E, Barash Y, Koller D, Friedman N, O'Shea EK. Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expression. Proceedings of the National Academy of Sciences of the United States of America. 101: 14315-22. PMID 15353587 DOI: 10.1073/Pnas.0405353101  0.435
2004 Raser JM, O'Shea EK. Control of stochasticity in eukaryotic gene expression. Science (New York, N.Y.). 304: 1811-4. PMID 15166317 DOI: 10.1126/Science.1098641  0.778
2004 Steger DJ, O'Shea EK. Genetic analysis of chromatin remodeling using budding yeast as a model. Methods in Enzymology. 377: 55-60. PMID 14979017 DOI: 10.1016/S0076-6879(03)77002-5  0.36
2004 Byrne M, Miller N, Springer M, O'Shea EK. A distal, high-affinity binding site on the cyclin-CDK substrate Pho4 is important for its phosphorylation and regulation. Journal of Molecular Biology. 335: 57-70. PMID 14659740 DOI: 10.1016/J.Jmb.2003.10.035  0.705
2003 Springer M, Wykoff DD, Miller N, O'Shea EK. Partially phosphorylated Pho4 activates transcription of a subset of phosphate-responsive genes. Plos Biology. 1: E28. PMID 14624238 DOI: 10.1371/Journal.Pbio.0000028  0.649
2003 Ghaemmaghami S, Huh WK, Bower K, Howson RW, Belle A, Dephoure N, O'Shea EK, Weissman JS. Global analysis of protein expression in yeast. Nature. 425: 737-41. PMID 14562106 DOI: 10.1038/Nature02046  0.783
2003 Huh WK, Falvo JV, Gerke LC, Carroll AS, Howson RW, Weissman JS, O'Shea EK. Global analysis of protein localization in budding yeast. Nature. 425: 686-91. PMID 14562095 DOI: 10.1038/Nature02026  0.777
2003 Steger DJ, Haswell ES, Miller AL, Wente SR, O'Shea EK. Regulation of chromatin remodeling by inositol polyphosphates. Science (New York, N.Y.). 299: 114-6. PMID 12434012 DOI: 10.1126/Science.1078062  0.696
2002 O'Rourke SM, Herskowitz I, O'Shea EK. Yeast go the whole HOG for the hyperosmotic response. Trends in Genetics : Tig. 18: 405-12. PMID 12142009 DOI: 10.1016/S0168-9525(02)02723-3  0.643
2002 Herskowitz I, O'Shea E. The 2001 Thomas Hunt Morgan Medal. Yasuji Oshima. Genetics. 160: 367-8. PMID 11894818  0.423
2002 Carroll AS, O'Shea EK. Pho85 and signaling environmental conditions. Trends in Biochemical Sciences. 27: 87-93. PMID 11852246 DOI: 10.1016/S0968-0004(01)02040-0  0.665
2001 Komeili A, O'Shea EK. New perspectives on nuclear transport. Annual Review of Genetics. 35: 341-64. PMID 11700287 DOI: 10.1146/Annurev.Genet.35.102401.090720  0.644
2001 Carroll AS, Bishop AC, DeRisi JL, Shokat KM, O'Shea EK. Chemical inhibition of the Pho85 cyclin-dependent kinase reveals a role in the environmental stress response. Proceedings of the National Academy of Sciences of the United States of America. 98: 12578-83. PMID 11675494 DOI: 10.1073/Pnas.211195798  0.69
2001 Huang S, Jeffery DA, Anthony MD, O'Shea EK. Functional analysis of the cyclin-dependent kinase inhibitor Pho81 identifies a novel inhibitory domain. Molecular and Cellular Biology. 21: 6695-705. PMID 11533256 DOI: 10.1128/Mcb.21.19.6695-6705.2001  0.772
2001 Jeffery DA, Springer M, King DS, O'Shea EK. Multi-site phosphorylation of Pho4 by the cyclin-CDK Pho80-Pho85 is semi-processive with site preference. Journal of Molecular Biology. 306: 997-1010. PMID 11237614 DOI: 10.1006/Jmbi.2000.4417  0.739
2001 Lenburg ME, O'Shea EK. Genetic evidence for a morphogenetic function of the Saccharomyces cerevisiae Pho85 cyclin-dependent kinase. Genetics. 157: 39-51. PMID 11139490  0.557
2000 Komeili A, Wedaman KP, O'Shea EK, Powers T. Mechanism of metabolic control. Target of rapamycin signaling links nitrogen quality to the activity of the Rtg1 and Rtg3 transcription factors. The Journal of Cell Biology. 151: 863-78. PMID 11076970 DOI: 10.1083/Jcb.151.4.863  0.719
2000 Komeili A, O'Shea EK. Nuclear transport and transcription. Current Opinion in Cell Biology. 12: 355-60. PMID 10801461 DOI: 10.1016/S0955-0674(00)00100-9  0.655
2000 O'Shea EK, Herskowitz I. The ins and outs of cell-polarity decisions. Nature Cell Biology. 2: E39-41. PMID 10707093 DOI: 10.1038/35004065  0.54
2000 Lau WT, Howson RW, Malkus P, Schekman R, O'Shea EK. Pho86p, an endoplasmic reticulum (ER) resident protein in Saccharomyces cerevisiae, is required for ER exit of the high-affinity phosphate transporter Pho84p. Proceedings of the National Academy of Sciences of the United States of America. 97: 1107-12. PMID 10655492 DOI: 10.1073/Pnas.97.3.1107  0.772
1999 Kaffman A, O'Shea EK. Regulation of nuclear localization: a key to a door. Annual Review of Cell and Developmental Biology. 15: 291-339. PMID 10611964 DOI: 10.1146/annurev.cellbio.15.1.291  0.382
1999 Komeili A, O'Shea EK. Roles of phosphorylation sites in regulating activity of the transcription factor Pho4. Science (New York, N.Y.). 284: 977-80. PMID 10320381 DOI: 10.1126/Science.284.5416.977  0.688
1999 Haswell ES, O'Shea EK. An in vitro system recapitulates chromatin remodeling at the PHO5 promoter. Molecular and Cellular Biology. 19: 2817-27. PMID 10082547 DOI: 10.1128/Mcb.19.4.2817  0.631
1998 Haswell ES, O'Shea EK. Specificity of ATP-dependent chromatin remodeling at the yeast PHO5 promoter. Cold Spring Harbor Symposia On Quantitative Biology. 63: 563-7. PMID 10384321  0.628
1998 Kaffman A, Rank NM, O'Neill EM, Huang LS, O'Shea EK. The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus. Nature. 396: 482-6. PMID 9853758 DOI: 10.1038/24898  0.593
1998 Kaffman A, Rank NM, O'Shea EK. Phosphorylation regulates association of the transcription factor Pho4 with its import receptor Pse1/Kap121. Genes & Development. 12: 2673-83. PMID 9732266  0.313
1996 Lenburg ME, O'Shea EK. Signaling phosphate starvation. Trends in Biochemical Sciences. 21: 383-7. PMID 8918192 DOI: 10.1016/S0968-0004(96)10048-7  0.632
1996 O'Neill EM, Kaffman A, Jolly ER, O'Shea EK. Regulation of PHO4 nuclear localization by the PHO80-PHO85 cyclin-CDK complex. Science (New York, N.Y.). 271: 209-12. PMID 8539622 DOI: 10.1126/Science.271.5246.209  0.797
1995 O'Neill EM, O'Shea EK. Transcriptional regulation. Cyclins in initiation. Nature. 374: 121-2. PMID 7877679 DOI: 10.1038/374121a0  0.395
1994 Kaffman A, Herskowitz I, Tjian R, O'Shea EK. Phosphorylation of the transcription factor PHO4 by a cyclin-CDK complex, PHO80-PHO85. Science (New York, N.Y.). 263: 1153-6. PMID 8108735 DOI: 10.1126/Science.8108735  0.72
1993 O'Shea EK, Lumb KJ, Kim PS. Peptide 'Velcro': design of a heterodimeric coiled coil. Current Biology : Cb. 3: 658-67. PMID 15335856 DOI: 10.1016/0960-9822(93)90063-T  0.68
1992 O'Shea EK, Rutkowski R, Kim PS. Mechanism of specificity in the Fos-Jun oncoprotein heterodimer. Cell. 68: 699-708. PMID 1739975 DOI: 10.1016/0092-8674(92)90145-3  0.509
1991 Rasmussen R, Benvegnu D, O'Shea EK, Kim PS, Alber T. X-ray scattering indicates that the leucine zipper is a coiled coil. Proceedings of the National Academy of Sciences of the United States of America. 88: 561-4. PMID 1988953 DOI: 10.1073/Pnas.88.2.561  0.464
1991 O'Shea EK, Klemm JD, Kim PS, Alber T. X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil. Science (New York, N.Y.). 254: 539-44. PMID 1948029 DOI: 10.1126/Science.1948029  0.437
1990 Oas TG, McIntosh LP, O'Shea EK, Dahlquist FW, Kim PS. Secondary structure of a leucine zipper determined by nuclear magnetic resonance spectroscopy. Biochemistry. 29: 2891-4. PMID 2337572 DOI: 10.1021/Bi00464A001  0.653
1990 Hu JC, O'Shea EK, Kim PS, Sauer RT. Sequence requirements for coiled-coils: analysis with lambda repressor-GCN4 leucine zipper fusions. Science (New York, N.Y.). 250: 1400-3. PMID 2147779 DOI: 10.1126/Science.2147779  0.457
1989 O'Shea EK, Rutkowski R, Kim PS. Evidence that the leucine zipper is a coiled coil. Science (New York, N.Y.). 243: 538-42. PMID 2911757 DOI: 10.1126/Science.2911757  0.477
1989 O'Shea EK, Rutkowski R, Stafford WF, Kim PS. Preferential heterodimer formation by isolated leucine zippers from fos and jun. Science (New York, N.Y.). 245: 646-8. PMID 2503872 DOI: 10.1126/Science.2503872  0.493
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