Soyon Y. Hong, Ph.D. - Publications

Affiliations: 
2012 Biology: Medical Sciences, Division of Harvard University, Cambridge, MA, United States 
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=1

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Schlepckow K, Morenas-Rodríguez E, Hong S, Haass C. Stimulation of TREM2 with agonistic antibodies-an emerging therapeutic option for Alzheimer's disease. The Lancet. Neurology. 22: 1048-1060. PMID 37863592 DOI: 10.1016/S1474-4422(23)00247-8  0.446
2023 Rueda-Carrasco J, Sokolova D, Lee SE, Childs T, Jurčáková N, Crowley G, De Schepper S, Ge JZ, Lachica JI, Toomey CE, Freeman OJ, Hardy J, Barnes SJ, Lashley T, Stevens B, ... ... Hong S, et al. Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models. The Embo Journal. e113246. PMID 37575021 DOI: 10.15252/embj.2022113246  0.321
2023 De Schepper S, Ge JZ, Crowley G, Ferreira LSS, Garceau D, Toomey CE, Sokolova D, Rueda-Carrasco J, Shin SH, Kim JS, Childs T, Lashley T, Burden JJ, Sasner M, Sala Frigerio C, ... ... Hong S, et al. Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease. Nature Neuroscience. PMID 36747024 DOI: 10.1038/s41593-023-01257-z  0.329
2022 Paolicelli RC, Sierra A, Stevens B, Tremblay ME, Aguzzi A, Ajami B, Amit I, Audinat E, Bechmann I, Bennett M, Bennett F, Bessis A, Biber K, Bilbo S, Blurton-Jones M, ... ... Hong S, et al. Microglia states and nomenclature: A field at its crossroads. Neuron. 110: 3458-3483. PMID 36327895 DOI: 10.1016/j.neuron.2022.10.020  0.371
2017 Hong S, Stevens B. TREM2: Keeping Microglia Fit during Good Times and Bad. Cell Metabolism. 26: 590-591. PMID 28978423 DOI: 10.1016/J.Cmet.2017.09.010  0.412
2017 Shi Q, Chowdhury S, Ma R, Le KX, Hong S, Caldarone BJ, Stevens B, Lemere CA. Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice. Science Translational Medicine. 9. PMID 28566429 DOI: 10.1126/Scitranslmed.Aaf6295  0.427
2017 Hong S, Wilton DK, Stevens B, Richardson DS. Structured Illumination Microscopy for the Investigation of Synaptic Structure and Function. Methods in Molecular Biology (Clifton, N.J.). 1538: 155-167. PMID 27943190 DOI: 10.1007/978-1-4939-6688-2_12  0.303
2016 Hong S, Stevens B. Microglia: Phagocytosing to Clear, Sculpt, and Eliminate. Developmental Cell. 38: 126-8. PMID 27459063 DOI: 10.1016/J.Devcel.2016.07.006  0.308
2016 Hong S, Beja-Glasser VF, Nfonoyim BM, Frouin A, Li S, Ramakrishnan S, Merry KM, Shi Q, Rosenthal A, Barres BA, Lemere CA, Selkoe DJ, Stevens B. Complement and microglia mediate early synapse loss in Alzheimer mouse models. Science (New York, N.Y.). PMID 27033548 DOI: 10.1126/Science.Aad8373  0.542
2015 Hong S, Dissing-Olesen L, Stevens B. New insights on the role of microglia in synaptic pruning in health and disease. Current Opinion in Neurobiology. 36: 128-134. PMID 26745839 DOI: 10.1016/J.Conb.2015.12.004  0.404
2015 Chen AC, Kim S, Shepardson N, Patel S, Hong S, Selkoe DJ. Physical and functional interaction between the α- and γ-secretases: A new model of regulated intramembrane proteolysis. The Journal of Cell Biology. 211: 1157-76. PMID 26694839 DOI: 10.1083/Jcb.201502001  0.551
2015 Shi Q, Colodner KJ, Matousek SB, Merry K, Hong S, Kenison JE, Frost JL, Le KX, Li S, Dodart JC, Caldarone BJ, Stevens B, Lemere CA. Complement C3-Deficient Mice Fail to Display Age-Related Hippocampal Decline. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 13029-42. PMID 26400934 DOI: 10.1523/Jneurosci.1698-15.2015  0.333
2014 Hong S, Ostaszewski BL, Yang T, O'Malley TT, Jin M, Yanagisawa K, Li S, Bartels T, Selkoe DJ. Soluble Aβ oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes. Neuron. 82: 308-19. PMID 24685176 DOI: 10.1016/J.Neuron.2014.02.027  0.481
2014 Lemere CA, Shi Q, Caldarone B, Chowdhury S, Ma R, Hong S, Stevens B. S4-02-03: COMPLEMENT IN ALZHEIMER'S DISEASE: LESSONS FROM C3-DEFICIENT MICE Alzheimer's & Dementia. 10: P240-P240. DOI: 10.1016/J.Jalz.2014.04.360  0.333
2013 Yang T, Hong S, O'Malley T, Sperling RA, Walsh DM, Selkoe DJ. New ELISAs with high specificity for soluble oligomers of amyloid β-protein detect natural Aβ oligomers in human brain but not CSF. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 99-112. PMID 23375565 DOI: 10.1016/J.Jalz.2012.11.005  0.607
2013 Shi Q, Caldarone B, Merry K, Hong S, McKinney PP, Frost J, Matousek S, Kenison J, Chowdhury S, Le KX, Stevens B, Lemere C. P2-375: Behavioral changes associated with complement C3-deficiency in aged Alzheimer's disease-like Tg mice Alzheimer's & Dementia. 9: P496-P497. DOI: 10.1016/J.Jalz.2013.05.1024  0.327
2012 Fu H, Liu B, Frost JL, Hong S, Jin M, Ostaszewski B, Shankar GM, Costantino IM, Carroll MC, Mayadas TN, Lemere CA. Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia. Glia. 60: 993-1003. PMID 22438044 DOI: 10.1002/Glia.22331  0.392
2011 Hong S, Quintero-Monzon O, Ostaszewski BL, Podlisny DR, Cavanaugh WT, Yang T, Holtzman DM, Cirrito JR, Selkoe DJ. Dynamic analysis of amyloid β-protein in behaving mice reveals opposing changes in ISF versus parenchymal Aβ during age-related plaque formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 15861-9. PMID 22049429 DOI: 10.1523/Jneurosci.3272-11.2011  0.544
2009 Li S, Hong S, Shepardson NE, Walsh DM, Shankar GM, Selkoe D. Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake. Neuron. 62: 788-801. PMID 19555648 DOI: 10.1016/J.Neuron.2009.05.012  0.602
2008 Nazer B, Hong S, Selkoe DJ. LRP promotes endocytosis and degradation, but not transcytosis, of the amyloid-beta peptide in a blood-brain barrier in vitro model. Neurobiology of Disease. 30: 94-102. PMID 18289866 DOI: 10.1016/J.Nbd.2007.12.005  0.509
2008 Giorgini F, Möller T, Kwan W, Zwilling D, Wacker JL, Hong S, Tsai LC, Cheah CS, Schwarcz R, Guidetti P, Muchowski PJ. Histone deacetylase inhibition modulates kynurenine pathway activation in yeast, microglia, and mice expressing a mutant huntingtin fragment. The Journal of Biological Chemistry. 283: 7390-400. PMID 18079112 DOI: 10.1074/Jbc.M708192200  0.312
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