Jason Flannick, Ph.D. - Publications

Affiliations: 
2009 Stanford University, Palo Alto, CA 

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Lek M, Karczewski KJ, Minikel EV, Samocha KE, Banks E, Fennell T, O'Donnell-Luria AH, Ware JS, Hill AJ, Cummings BB, Tukiainen T, Birnbaum DP, Kosmicki JA, Duncan LE, Estrada K, ... ... Flannick J, et al. Analysis of protein-coding genetic variation in 60,706 humans. Nature. 536: 285-291. PMID 27535533 DOI: 10.1038/nature19057  0.52
2016 Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, Agarwala V, Gaulton KJ, Ma C, Fontanillas P, Moutsianas L, McCarthy DJ, Rivas MA, Perry JR, Sim X, Blackwell TW, Robertson NR, et al. The genetic architecture of type 2 diabetes. Nature. PMID 27398621 DOI: 10.1038/nature18642  0.52
2016 Flannick J, Johansson S, Njølstad PR. Common and rare forms of diabetes mellitus: towards a continuum of diabetes subtypes. Nature Reviews. Endocrinology. PMID 27080136 DOI: 10.1038/nrendo.2016.50  0.52
2016 Clapham KR, Chu AY, Wessel J, Natarajan P, Flannick J, Rivas MA, Sartori S, Mehran R, Baber U, Fuster V, Scott RA, Rader DJ, Boehnke M, McCarthy MI, Altshuler DM, et al. A null mutation in ANGPTL8 does not associate with either plasma glucose or type 2 diabetes in humans. Bmc Endocrine Disorders. 16: 7. PMID 26822414 DOI: 10.1186/s12902-016-0088-8  0.52
2016 Imamura M, Takahashi A, Yamauchi T, Hara K, Yasuda K, Grarup N, Zhao W, Wang X, Huerta-Chagoya A, Hu C, Moon S, Long J, Kwak SH, Rasheed A, Saxena R, ... ... Flannick J, et al. Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes. Nature Communications. 7: 10531. PMID 26818947 DOI: 10.1038/ncomms10531  0.52
2015 Kim YJ, Lee J, Kim BJ, Park T. A new strategy for enhancing imputation quality of rare variants from next-generation sequencing data via combining SNP and exome chip data. Bmc Genomics. 16: 1109. PMID 26715385 DOI: 10.1186/s12864-015-2192-y  0.52
2015 Gaulton KJ, Ferreira T, Lee Y, Raimondo A, Mägi R, Reschen ME, Mahajan A, Locke A, William Rayner N, Robertson N, Scott RA, Prokopenko I, Scott LJ, Green T, Sparso T, ... ... Flannick J, et al. Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. Nature Genetics. PMID 26551672 DOI: 10.1038/ng.3437  0.52
2015 Mahajan A, Sim X, Ng HJ, Manning A, Rivas MA, Highland HM, Locke AE, Grarup N, Im HK, Cingolani P, Flannick J, Fontanillas P, Fuchsberger C, Gaulton KJ, Teslovich TM, et al. Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus. Plos Genetics. 11: e1004876. PMID 25625282 DOI: 10.1371/journal.pgen.1004876  0.52
2015 Roberts AM, Ware JS, Herman DS, Schafer S, Baksi J, Bick AG, Buchan RJ, Walsh R, John S, Wilkinson S, Mazzarotto F, Felkin LE, Gong S, MacArthur JA, Cunningham F, ... Flannick J, et al. Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease. Science Translational Medicine. 7: 270ra6. PMID 25589632 DOI: 10.1126/scitranslmed.3010134  0.52
2014 Lim ET, Liu YP, Chan Y, Tiinamaija T, Käräjämäki A, Madsen E, Altshuler DM, Raychaudhuri S, Groop L, Flannick J, Hirschhorn JN, Katsanis N, Daly MJ. A novel test for recessive contributions to complex diseases implicates Bardet-Biedl syndrome gene BBS10 in idiopathic type 2 diabetes and obesity. American Journal of Human Genetics. 95: 509-20. PMID 25439097 DOI: 10.1016/j.ajhg.2014.09.015  0.52
2014 Jaiswal S, Fontanillas P, Flannick J, Manning A, Grauman PV, Mar BG, Lindsley RC, Mermel CH, Burtt N, Chavez A, Higgins JM, Moltchanov V, Kuo FC, Kluk MJ, Henderson B, et al. Age-related clonal hematopoiesis associated with adverse outcomes. The New England Journal of Medicine. 371: 2488-98. PMID 25426837 DOI: 10.1056/NEJMoa1408617  0.52
2014 Majithia AR, Flannick J, Shahinian P, Guo M, Bray MA, Fontanillas P, Gabriel SB, Rosen ED, Altshuler D. Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes. Proceedings of the National Academy of Sciences of the United States of America. 111: 13127-32. PMID 25157153 DOI: 10.1073/pnas.1410428111  0.52
2014 Lim ET, Würtz P, Havulinna AS, Palta P, Tukiainen T, Rehnström K, Esko T, Mägi R, Inouye M, Lappalainen T, Chan Y, Salem RM, Lek M, Flannick J, Sim X, et al. Distribution and medical impact of loss-of-function variants in the Finnish founder population. Plos Genetics. 10: e1004494. PMID 25078778 DOI: 10.1371/journal.pgen.1004494  0.52
2014 Wang SR, Agarwala V, Flannick J, Chiang CW, Altshuler D, Hirschhorn JN. Simulation of Finnish population history, guided by empirical genetic data, to assess power of rare-variant tests in Finland. American Journal of Human Genetics. 94: 710-20. PMID 24768551 DOI: 10.1016/j.ajhg.2014.03.019  0.52
2014 Flannick J, Thorleifsson G, Beer NL, Jacobs SB, Grarup N, Burtt NP, Mahajan A, Fuchsberger C, Atzmon G, Benediktsson R, Blangero J, Bowden DW, Brandslund I, Brosnan J, Burslem F, et al. Loss-of-function mutations in SLC30A8 protect against type 2 diabetes. Nature Genetics. 46: 357-63. PMID 24584071 DOI: 10.1038/ng.2915  0.52
2014 Lange LA, Hu Y, Zhang H, Xue C, Schmidt EM, Tang ZZ, Bizon C, Lange EM, Smith JD, Turner EH, Jun G, Kang HM, Peloso G, Auer P, Li KP, ... Flannick J, et al. Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. American Journal of Human Genetics. 94: 233-45. PMID 24507775 DOI: 10.1016/j.ajhg.2014.01.010  0.52
2014 Ito K, Bick AG, Flannick J, Friedman DJ, Genovese G, Parfenov MG, Depalma SR, Gupta N, Gabriel SB, Taylor HA, Fox ER, Newton-Cheh C, Kathiresan S, Hirschhorn JN, Altshuler DM, et al. Increased burden of cardiovascular disease in carriers of APOL1 genetic variants. Circulation Research. 114: 845-50. PMID 24379297 DOI: 10.1161/CIRCRESAHA.114.302347  0.52
2014 Gaulton K, Flannick J, Fuchsberger C. Whole genome and exome sequencing of type 2 diabetes Frontiers in Diabetes. 23: 29-41. DOI: 10.1159/000362465  0.52
2013 Agarwala V, Flannick J, Sunyaev S, Altshuler D. Evaluating empirical bounds on complex disease genetic architecture. Nature Genetics. 45: 1418-27. PMID 24141362 DOI: 10.1038/ng.2804  0.52
2013 Flannick J, Beer NL, Bick AG, Agarwala V, Molnes J, Gupta N, Burtt NP, Florez JC, Meigs JB, Taylor H, Lyssenko V, Irgens H, Fox E, Burslem F, Johansson S, et al. Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes. Nature Genetics. 45: 1380-5. PMID 24097065 DOI: 10.1038/ng.2794  0.52
2013 Liu L, Sabo A, Neale BM, Nagaswamy U, Stevens C, Lim E, Bodea CA, Muzny D, Reid JG, Banks E, Coon H, Depristo M, Dinh H, Fennel T, Flannick J, et al. Analysis of rare, exonic variation amongst subjects with autism spectrum disorders and population controls. Plos Genetics. 9: e1003443. PMID 23593035 DOI: 10.1371/journal.pgen.1003443  0.52
2013 Lim ET, Raychaudhuri S, Sanders SJ, Stevens C, Sabo A, MacArthur DG, Neale BM, Kirby A, Ruderfer DM, Fromer M, Lek M, Liu L, Flannick J, Ripke S, Nagaswamy U, et al. Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders. Neuron. 77: 235-42. PMID 23352160 DOI: 10.1016/j.neuron.2012.12.029  0.52
2013 Diogo D, Kurreeman F, Stahl EA, Liao KP, Gupta N, Greenberg JD, Rivas MA, Hickey B, Flannick J, Thomson B, Guiducci C, Ripke S, Adzhubey I, Barton A, Kremer JM, et al. Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis. American Journal of Human Genetics. 92: 15-27. PMID 23261300 DOI: 10.1016/j.ajhg.2012.11.012  0.52
2012 Bick AG, Flannick J, Ito K, Cheng S, Vasan RS, Parfenov MG, Herman DS, DePalma SR, Gupta N, Gabriel SB, Funke BH, Rehm HL, Benjamin EJ, Aragam J, Taylor HA, et al. Burden of rare sarcomere gene variants in the Framingham and Jackson Heart Study cohorts. American Journal of Human Genetics. 91: 513-9. PMID 22958901 DOI: 10.1016/j.ajhg.2012.07.017  0.52
2012 Flannick J, Korn JM, Fontanillas P, Grant GB, Banks E, Depristo MA, Altshuler D. Efficiency and power as a function of sequence coverage, SNP array density, and imputation. Plos Computational Biology. 8: e1002604. PMID 22807667 DOI: 10.1371/journal.pcbi.1002604  0.52
2012 Neale BM, Kou Y, Liu L, Ma'ayan A, Samocha KE, Sabo A, Lin CF, Stevens C, Wang LS, Makarov V, Polak P, Yoon S, Maguire J, Crawford EL, Campbell NG, ... ... Flannick J, et al. Patterns and rates of exonic de novo mutations in autism spectrum disorders. Nature. 485: 242-5. PMID 22495311 DOI: 10.1038/nature11011  0.52
2011 Jimenez NL, Flannick J, Yahyavi M, Li J, Bardakjian T, Tonkin L, Schneider A, Sherr EH, Slavotinek AM. Targeted 'next-generation' sequencing in anophthalmia and microphthalmia patients confirms SOX2, OTX2 and FOXE3 mutations. Bmc Medical Genetics. 12: 172. PMID 22204637 DOI: 10.1186/1471-2350-12-172  0.52
2010 Srinivasan BS, Evans EA, Flannick J, Patterson AS, Chang CC, Pham T, Young S, Kaushal A, Lee J, Jacobson JL, Patrizio P. A universal carrier test for the long tail of Mendelian disease. Reproductive Biomedicine Online. 21: 537-51. PMID 20729146 DOI: 10.1016/j.rbmo.2010.05.012  0.52
2009 Flannick J, Novak A, Do CB, Srinivasan BS, Batzoglou S. Automatic parameter learning for multiple local network alignment. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 16: 1001-22. PMID 19645599 DOI: 10.1089/cmb.2009.0099  0.52
2008 Boutte CC, Srinivasan BS, Flannick JA, Novak AF, Martens AT, Batzoglou S, Viollier PH, Crosson S. Genetic and computational identification of a conserved bacterial metabolic module. Plos Genetics. 4: e1000310. PMID 19096521 DOI: 10.1371/journal.pgen.1000310  0.52
2008 Flannick J, Novak A, Do CB, Srinivasan BS, Batzoglou S. Automatic parameter learning for multiple network alignment Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4955: 214-231. DOI: 10.1007/978-3-540-78839-3_19  0.52
2007 Srinivasan BS, Shah NH, Flannick JA, Abeliuk E, Novak AF, Batzoglou S. Current progress in network research: toward reference networks for key model organisms. Briefings in Bioinformatics. 8: 318-32. PMID 17728341 DOI: 10.1093/bib/bbm038  0.52
2006 Flannick J, Novak A, Srinivasan BS, McAdams HH, Batzoglou S. Graemlin: general and robust alignment of multiple large interaction networks. Genome Research. 16: 1169-81. PMID 16899655 DOI: 10.1101/gr.5235706  0.52
2006 Srinivasan BS, Novak AF, Flannick JA, Batzoglou S, McAdams HH. Integrated protein interaction networks for 11 microbes Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 3909: 1-14.  0.52
2005 Flannick J, Batzoglou S. Using multiple alignments to improve seeded local alignment algorithms. Nucleic Acids Research. 33: 4563-77. PMID 16100379 DOI: 10.1093/nar/gki767  0.52
2005 Burdick D, Calimlim M, Flannick J, Gehrke J, Yiu T. MAFIA: A maximal frequent itemset algorithm Ieee Transactions On Knowledge and Data Engineering. 17: 1490-1504. DOI: 10.1109/TKDE.2005.183  0.52
2002 Ayres J, Flannick J, Gehrke J, Yiu T. Sequential pattern mining using A bitmap representation Proceedings of the Acm Sigkdd International Conference On Knowledge Discovery and Data Mining. 429-435.  0.52
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