| Year |
Citation |
Score |
| 2017 |
Shi Y, Yamada K, Liddelow SA, Smith ST, Zhao L, Luo W, Tsai RM, Spina S, Grinberg LT, Rojas JC, Gallardo G, Wang K, Roh J, Robinson G, Finn MB, ... ... Paul SM, et al. ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy. Nature. 549: 523-527. PMID 28959956 DOI: 10.1038/Nature24016 |
0.306 |
|
| 2011 |
Sullivan PM, Han B, Liu F, Mace BE, Ervin JF, Wu S, Koger D, Paul S, Bales KR. Reduced levels of human apoE4 protein in an animal model of cognitive impairment Neurobiology of Aging. 32: 791-801. PMID 19577821 DOI: 10.1016/J.Neurobiolaging.2009.05.011 |
0.309 |
|
| 2009 |
Rohe M, Synowitz M, Glass R, Paul SM, Nykjaer A, Willnow TE. Brain-derived neurotrophic factor reduces amyloidogenic processing through control of SORLA gene expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 15472-8. PMID 20007471 DOI: 10.1523/Jneurosci.3960-09.2009 |
0.359 |
|
| 2009 |
Kim J, Castellano JM, Jiang H, Basak JM, Parsadanian M, Pham V, Mason SM, Paul SM, Holtzman DM. Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance. Neuron. 64: 632-44. PMID 20005821 DOI: 10.1016/J.Neuron.2009.11.013 |
0.35 |
|
| 2009 |
Bales KR, Liu F, Wu S, Lin S, Koger D, DeLong C, Hansen JC, Sullivan PM, Paul SM. Human APOE isoform-dependent effects on brain beta-amyloid levels in PDAPP transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6771-9. PMID 19474305 DOI: 10.1523/Jneurosci.0887-09.2009 |
0.325 |
|
| 2009 |
Zhao L, Lin S, Bales KR, Gelfanova V, Koger D, Delong C, Hale J, Liu F, Hunter JM, Paul SM. Macrophage-mediated degradation of beta-amyloid via an apolipoprotein E isoform-dependent mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 3603-12. PMID 19295164 DOI: 10.1523/Jneurosci.5302-08.2009 |
0.33 |
|
| 2008 |
Rohe M, Carlo AS, Breyhan H, Sporbert A, Militz D, Schmidt V, Wozny C, Harmeier A, Erdmann B, Bales KR, Wolf S, Kempermann G, Paul SM, Schmitz D, Bayer TA, et al. Sortilin-related receptor with A-type repeats (SORLA) affects the amyloid precursor protein-dependent stimulation of ERK signaling and adult neurogenesis. The Journal of Biological Chemistry. 283: 14826-34. PMID 18362153 DOI: 10.1074/Jbc.M710574200 |
0.374 |
|
| 2008 |
Wahrle SE, Jiang H, Parsadanian M, Kim J, Li A, Knoten A, Jain S, Hirsch-Reinshagen V, Wellington CL, Bales KR, Paul SM, Holtzman DM. Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease. The Journal of Clinical Investigation. 118: 671-82. PMID 18202749 DOI: 10.1172/Jci33622 |
0.329 |
|
| 2008 |
Zhou Y, Suram A, Venugopal C, Prakasam A, Lin S, Su Y, Li B, Paul SM, Sambamurti K. Geranylgeranyl pyrophosphate stimulates gamma-secretase to increase the generation of Abeta and APP-CTFgamma. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 47-54. PMID 17666454 DOI: 10.1096/Fj.07-8175Com |
0.321 |
|
| 2007 |
Cao G, Bales KR, DeMattos RB, Paul SM. Liver X receptor-mediated gene regulation and cholesterol homeostasis in brain: relevance to Alzheimer's disease therapeutics. Current Alzheimer Research. 4: 179-84. PMID 17430244 DOI: 10.2174/156720507780362173 |
0.349 |
|
| 2007 |
Costa DA, Cracchiolo JR, Bachstetter AD, Hughes TF, Bales KR, Paul SM, Mervis RF, Arendash GW, Potter H. Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanisms. Neurobiology of Aging. 28: 831-44. PMID 16730391 DOI: 10.1016/J.Neurobiolaging.2006.04.009 |
0.306 |
|
| 2006 |
Zerbinatti CV, Wahrle SE, Kim H, Cam JA, Bales K, Paul SM, Holtzman DM, Bu G. Apolipoprotein E and low density lipoprotein receptor-related protein facilitate intraneuronal Abeta42 accumulation in amyloid model mice. The Journal of Biological Chemistry. 281: 36180-6. PMID 17012232 DOI: 10.1074/Jbc.M604436200 |
0.346 |
|
| 2006 |
Bales KR, Tzavara ET, Wu S, Wade MR, Bymaster FP, Paul SM, Nomikos GG. Cholinergic dysfunction in a mouse model of Alzheimer disease is reversed by an anti-A beta antibody. The Journal of Clinical Investigation. 116: 825-32. PMID 16498501 DOI: 10.1172/Jci27120 |
0.315 |
|
| 2006 |
Arndash GW, Cracchiolo JR, Costa DA, Mori T, Hughes TF, Bales KR, Paul SM, Potter H. P4-322: Complete environmental enrichment is required to protect AD transgenic mice against cognitive impairment, reduce a-beta deposition, and increase synaptophysin staining: Involvement of both amyloid-dependent and independent mechanisms Alzheimer's & Dementia. 2: S611-S611. DOI: 10.1016/J.Jalz.2006.05.2063 |
0.303 |
|
| 2005 |
Cirrito JR, Yamada KA, Finn MB, Sloviter RS, Bales KR, May PC, Schoepp DD, Paul SM, Mennerick S, Holtzman DM. Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo. Neuron. 48: 913-22. PMID 16364896 DOI: 10.1016/J.Neuron.2005.10.028 |
0.318 |
|
| 2005 |
Cirrito JR, Deane R, Fagan AM, Spinner ML, Parsadanian M, Finn MB, Jiang H, Prior JL, Sagare A, Bales KR, Paul SM, Zlokovic BV, Piwnica-Worms D, Holtzman DM. P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model. The Journal of Clinical Investigation. 115: 3285-90. PMID 16239972 DOI: 10.1172/Jci25247 |
0.337 |
|
| 2005 |
Esh C, Patton L, Kalback W, Kokjohn TA, Lopez J, Brune D, Newell AJ, Beach T, Schenk D, Games D, Paul S, Bales K, Ghetti B, Castaño EM, Roher AE. Altered APP processing in PDAPP (Val717 --> Phe) transgenic mice yields extended-length Abeta peptides. Biochemistry. 44: 13807-19. PMID 16229470 DOI: 10.1021/Bi051213+ |
0.316 |
|
| 2005 |
Wahrle SE, Jiang H, Parsadanian M, Hartman RE, Bales KR, Paul SM, Holtzman DM. Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease. The Journal of Biological Chemistry. 280: 43236-42. PMID 16207708 DOI: 10.1074/Jbc.M508780200 |
0.314 |
|
| 2005 |
Andersen OM, Reiche J, Schmidt V, Gotthardt M, Spoelgen R, Behlke J, von Arnim CA, Breiderhoff T, Jansen P, Wu X, Bales KR, Cappai R, Masters CL, Gliemann J, Mufson EJ, ... ... Paul SM, et al. Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein. Proceedings of the National Academy of Sciences of the United States of America. 102: 13461-6. PMID 16174740 DOI: 10.1073/Pnas.0503689102 |
0.364 |
|
| 2005 |
Fryer JD, Simmons K, Parsadanian M, Bales KR, Paul SM, Sullivan PM, Holtzman DM. Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2803-10. PMID 15772340 DOI: 10.1523/Jneurosci.5170-04.2005 |
0.337 |
|
| 2005 |
Green PS, Bales K, Paul S, Bu G. Estrogen therapy fails to alter amyloid deposition in the PDAPP model of Alzheimer's disease Endocrinology. 146: 2774-2781. PMID 15731362 DOI: 10.1210/En.2004-1433 |
0.34 |
|
| 2005 |
Brendza RP, Bacskai BJ, Cirrito JR, Simmons KA, Skoch JM, Klunk WE, Mathis CA, Bales KR, Paul SM, Hyman BT, Holtzman DM. Anti-Abeta antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice. The Journal of Clinical Investigation. 115: 428-33. PMID 15668737 DOI: 10.1172/Jci23269 |
0.324 |
|
| 2005 |
Racke MM, Boone LI, Hepburn DL, Parsadainian M, Bryan MT, Ness DK, Piroozi KS, Jordan WH, Brown DD, Hoffman WP, Holtzman DM, Bales KR, Gitter BD, May PC, Paul SM, et al. Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 629-36. PMID 15659599 DOI: 10.1523/Jneurosci.4337-04.2005 |
0.312 |
|
| 2005 |
Dodart JC, Marr RA, Koistinaho M, Gregersen BM, Malkani S, Verma IM, Paul SM. Gene delivery of human apolipoprotein E alters brain Abeta burden in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 102: 1211-6. PMID 15657137 DOI: 10.1073/Pnas.0409072102 |
0.335 |
|
| 2004 |
Costa DA, Nilsson LN, Bales KR, Paul SM, Potter H. Apolipoprotein is required for the formation of filamentous amyloid, but not for amorphous Abeta deposition, in an AbetaPP/PS double transgenic mouse model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 6: 509-14. PMID 15505373 DOI: 10.3233/Jad-2004-6508 |
0.319 |
|
| 2004 |
Fagan AM, Christopher E, Taylor JW, Parsadanian M, Spinner M, Watson M, Fryer JD, Wahrle S, Bales KR, Paul SM, Holtzman DM. ApoAI deficiency results in marked reductions in plasma cholesterol but no alterations in amyloid-beta pathology in a mouse model of Alzheimer's disease-like cerebral amyloidosis. The American Journal of Pathology. 165: 1413-22. PMID 15466405 DOI: 10.1016/S0002-9440(10)63399-8 |
0.315 |
|
| 2004 |
Nilsson LN, Arendash GW, Leighty RE, Costa DA, Low MA, Garcia MF, Cracciolo JR, Rojiani A, Wu X, Bales KR, Paul SM, Potter H. Cognitive impairment in PDAPP mice depends on ApoE and ACT-catalyzed amyloid formation. Neurobiology of Aging. 25: 1153-67. PMID 15312961 DOI: 10.1016/J.Neurobiolaging.2003.12.011 |
0.321 |
|
| 2004 |
Koistinaho M, Lin S, Wu X, Esterman M, Koger D, Hanson J, Higgs R, Liu F, Malkani S, Bales KR, Paul SM. Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides. Nature Medicine. 10: 719-26. PMID 15195085 DOI: 10.1038/Nm1058 |
0.326 |
|
| 2004 |
Su Y, Ryder J, Li B, Wu X, Fox N, Solenberg P, Brune K, Paul S, Zhou Y, Liu F, Ni B. Lithium, a common drug for bipolar disorder treatment, regulates amyloid-β precursor protein processing Biochemistry. 43: 6899-6908. PMID 15170327 DOI: 10.1021/Bi035627J |
0.327 |
|
| 2004 |
Zerbinatti CV, Wozniak DF, Cirrito J, Cam JA, Osaka H, Bales KR, Zhuo M, Paul SM, Holtzman DM, Bu G. Increased soluble amyloid-beta peptide and memory deficits in amyloid model mice overexpressing the low-density lipoprotein receptor-related protein. Proceedings of the National Academy of Sciences of the United States of America. 101: 1075-80. PMID 14732699 DOI: 10.1073/Pnas.0305803101 |
0.34 |
|
| 2004 |
Liang Y, Lin S, Beyer TP, Zhang Y, Wu X, Bales KR, DeMattos RB, May PC, Li SD, Jiang XC, Eacho PI, Cao G, Paul SM. A liver X receptor and retinoid X receptor heterodimer mediates apolipoprotein E expression, secretion and cholesterol homeostasis in astrocytes. Journal of Neurochemistry. 88: 623-34. PMID 14720212 DOI: 10.1111/J.1471-4159.2004.02183.X |
0.335 |
|
| 2004 |
DeMattos RB, Boone LI, Hepburn DL, Parsadanian M, Bryan MT, Ness DK, Piroozi KS, Holtzman DM, Bales KR, Gitter BD, Paul SM, Racke M. P4-358 In vitro and in vivo characterization of beta-amyloid antibodies binding to cerebral amyloid angiopathy (CAA) and the selective exacerbation of CAA-associated microhemorrhage Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81916-X |
0.304 |
|
| 2003 |
Brendza RP, Simmons K, Bales KR, Paul SM, Goldberg MP, Holtzman DM. Use of YFP to study amyloid-beta associated neurite alterations in live brain slices. Neurobiology of Aging. 24: 1071-7. PMID 14643378 DOI: 10.1016/J.Neurobiolaging.2003.04.008 |
0.305 |
|
| 2003 |
Zhou Y, Su Y, Li B, Liu F, Ryder JW, Wu X, Gonzalez-DeWhitt PA, Gelfanova V, Hale JE, May PC, Paul SM, Ni B. Nonsteroidal anti-inflammatory drugs can lower amyloidogenic Abeta42 by inhibiting Rho. Science (New York, N.Y.). 302: 1215-7. PMID 14615541 DOI: 10.1126/Science.1090154 |
0.308 |
|
| 2003 |
Brendza RP, O'Brien C, Simmons K, McKeel DW, Bales KR, Paul SM, Olney JW, Sanes JR, Holtzman DM. PDAPP; YFP double transgenic mice: a tool to study amyloid-beta associated changes in axonal, dendritic, and synaptic structures. The Journal of Comparative Neurology. 456: 375-83. PMID 12532409 DOI: 10.1002/Cne.10536 |
0.309 |
|
| 2002 |
Dodart JC, Mathis C, Bales KR, Paul SM. Does my mouse have Alzheimer's disease? Genes, Brain, and Behavior. 1: 142-55. PMID 12884970 DOI: 10.1034/J.1601-183X.2002.10302.X |
0.313 |
|
| 2002 |
Holtzman DM, Bales KR, Paul SM, DeMattos RB. Abeta immunization and anti-Abeta antibodies: potential therapies for the prevention and treatment of Alzheimer's disease. Advanced Drug Delivery Reviews. 54: 1603-13. PMID 12453677 DOI: 10.1016/S0169-409X(02)00158-8 |
0.332 |
|
| 2002 |
Dodart JC, Bales KR, Johnstone EM, Little SP, Paul SM. Apolipoprotein E alters the processing of the beta-amyloid precursor protein in APP(V717F) transgenic mice. Brain Research. 955: 191-9. PMID 12419536 DOI: 10.1016/S0006-8993(02)03437-6 |
0.327 |
|
| 2002 |
DeMattos RB, O'dell MA, Parsadanian M, Taylor JW, Harmony JA, Bales KR, Paul SM, Aronow BJ, Holtzman DM. Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 99: 10843-8. PMID 12145324 DOI: 10.1073/Pnas.162228299 |
0.317 |
|
| 2002 |
Fagan AM, Watson M, Parsadanian M, Bales KR, Paul SM, Holtzman DM. Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease. Neurobiology of Disease. 9: 305-18. PMID 11950276 DOI: 10.1006/Nbdi.2002.0483 |
0.318 |
|
| 2002 |
Dodart JC, Bales KR, Gannon KS, Greene SJ, DeMattos RB, Mathis C, DeLong CA, Wu S, Wu X, Holtzman DM, Paul SM. Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model. Nature Neuroscience. 5: 452-7. PMID 11941374 DOI: 10.1038/Nn842 |
0.308 |
|
| 2002 |
DeMattos RB, Bales KR, Cummins DJ, Paul SM, Holtzman DM. Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease. Science (New York, N.Y.). 295: 2264-7. PMID 11910111 DOI: 10.1126/Science.1067568 |
0.33 |
|
| 2001 |
Qiao X, Cummins DJ, Paul SM. Neuroinflammation-induced acceleration of amyloid deposition in the APPV717F transgenic mouse. The European Journal of Neuroscience. 14: 474-82. PMID 11553297 DOI: 10.1046/J.0953-816X.2001.01666.X |
0.31 |
|
| 2001 |
Fishman CE, Cummins DJ, Bales KR, DeLong CA, Esterman MA, Hanson JC, White SL, Paul SM, Jordan WH. Statistical aspects of quantitative image analysis of beta-amyloid in the APP(V717F) transgenic mouse model of Alzheimer's disease. Journal of Neuroscience Methods. 108: 145-52. PMID 11478973 DOI: 10.1016/S0165-0270(01)00381-8 |
0.318 |
|
| 2001 |
Naidu A, Catalano R, Bales K, Wu S, Paul SM, Cordell B. Conversion of brain apolipoprotein E to an insoluble form in a mouse model of Alzheimer disease. Neuroreport. 12: 1265-70. PMID 11338204 DOI: 10.1097/00001756-200105080-00042 |
0.331 |
|
| 2001 |
Nilsson LNG, Bales KR, DiCarlo G, Gordon MN, Morgan D, Paul SM, Potter H. α-1-Antichymotrypsin Promotes β-Sheet Amyloid Plaque Deposition in a Transgenic Mouse Model of Alzheimer's Disease The Journal of Neuroscience. 21: 1444-1451. DOI: 10.1523/Jneurosci.21-05-01444.2001 |
0.316 |
|
| 2000 |
Irizarry MC, Rebeck GW, Cheung B, Bales K, Paul SM, Holzman D, Hyman BT. Modulation of Aβ deposition in APP transgenic mice by an apolipoprotein E null background Annals of the New York Academy of Sciences. 920: 171-178. PMID 11193147 DOI: 10.1111/J.1749-6632.2000.Tb06919.X |
0.339 |
|
| 2000 |
Holtzman DM, Fagan AM, Mackey B, Tenkova T, Sartorius L, Paul SM, Bales K, Ashe KH, Irizarry MC, Hyman BT. Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model. Annals of Neurology. 47: 739-47. PMID 10852539 DOI: 10.1002/1531-8249(200006)47:6<739::Aid-Ana6>3.0.Co;2-8 |
0.326 |
|
| 2000 |
Holtzman DM, Bales KR, Tenkova T, Fagan AM, Parsadanian M, Sartorius LJ, Mackey B, Olney J, McKeel D, Wozniak D, Paul SM. Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 97: 2892-7. PMID 10694577 DOI: 10.1073/Pnas.050004797 |
0.319 |
|
| 2000 |
Sheng JG, Mrak RE, Bales KR, Cordell B, Paul SM, Jones RA, Woodward S, Zhou XQ, McGinness JM, Griffin WS. Overexpression of the neuritotrophic cytokine S100beta precedes the appearance of neuritic beta-amyloid plaques in APPV717F mice. Journal of Neurochemistry. 74: 295-301. PMID 10617132 DOI: 10.1046/J.1471-4159.2000.0740295.X |
0.32 |
|
| 2000 |
Wu X, Glinn MA, Ostrowski NL, Su Y, Ni B, Cole HW, Bryant HU, Paul SM. Raloxifene and estradiol benzoate both fully restore hippocampal choline acetyltransferase activity in ovariectomized rats. Brain Research. 847: 98-104. PMID 10564741 DOI: 10.1016/S0006-8993(99)02062-4 |
0.307 |
|
| 1999 |
Dodart JC, Mathis C, Bales KR, Paul SM, Ungerer A. Early regional cerebral glucose hypometabolism in transgenic mice overexpressing the V717F β-amyloid precursor protein Neuroscience Letters. 277: 49-52. PMID 10643895 DOI: 10.1016/S0304-3940(99)00847-2 |
0.303 |
|
| 1998 |
Bales KR, Du Y, Dodel RC, Yan GM, Hamilton-Byrd E, Paul SM. The NF-kappaB/Rel family of proteins mediates Abeta-induced neurotoxicity and glial activation. Brain Research. Molecular Brain Research. 57: 63-72. PMID 9630519 DOI: 10.1016/S0169-328X(98)00066-7 |
0.324 |
|
| 1998 |
Montpied P, Yan GM, Paul SM, Morrow AL. Transient increase in cerebellar transcriptional activity precedes the expression of GABA(A) receptor alpha6 subunit mRNA during postnatal maturation. Developmental Neuroscience. 20: 74-82. PMID 9600393 DOI: 10.1159/000017301 |
0.495 |
|
| 1996 |
Felder CC, Nielsen A, Briley EM, Palkovits M, Priller J, Axelrod J, Nguyen DN, Richardson JM, Riggin RM, Koppel GA, Paul SM, Becker GW. Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and rat. Febs Letters. 393: 231-5. PMID 8814296 DOI: 10.1016/0014-5793(96)00891-5 |
0.318 |
|
| 1995 |
Morrow AL, Devaud LL, Purdy RH, Paul SM. Neuroactive steroid modulators of the stress response. Annals of the New York Academy of Sciences. 771: 257-72. PMID 8597405 DOI: 10.1111/J.1749-6632.1995.Tb44687.X |
0.658 |
|
| 1993 |
Montpied P, Weizman A, Weizman R, Kook KA, Morrow AL, Paul SM. Repeated swim-stress reduces GABAA receptor alpha subunit mRNAs in the mouse hippocampus. Brain Research. Molecular Brain Research. 18: 267-72. PMID 7684486 DOI: 10.1016/0169-328X(93)90199-Y |
0.512 |
|
| 1992 |
Leppin C, Finiels-Marlier F, Crawley JN, Montpied P, Paul SM. Failure of a protein synthesis inhibitor to modify glutamate receptor-mediated neurotoxicity in vivo. Brain Research. 581: 168-70. PMID 1379868 DOI: 10.1016/0006-8993(92)90359-H |
0.306 |
|
| 1992 |
Purdy RH, Moore PH, Morrow AL, Paul SM. Neurosteroids and GABAA receptor function. Advances in Biochemical Psychopharmacology. 47: 87-92. PMID 1354922 |
0.425 |
|
| 1991 |
Purdy RH, Morrow AL, Moore PH, Paul SM. Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain. Proceedings of the National Academy of Sciences of the United States of America. 88: 4553-7. PMID 1852011 |
0.463 |
|
| 1991 |
Morrow AL, Montpied P, Paul SM. GABAA receptor function and expression following chronic ethanol and barbiturate administration. Annals of the New York Academy of Sciences. 625: 496-507. PMID 1711815 DOI: 10.1111/J.1749-6632.1991.Tb33880.X |
0.484 |
|
| 1991 |
Montpied P, Morrow AL, Karanian JW, Ginns EI, Martin BM, Paul SM. Prolonged ethanol inhalation decreases gamma-aminobutyric acidA receptor alpha subunit mRNAs in the rat cerebral cortex. Molecular Pharmacology. 39: 157-63. PMID 1705000 |
0.439 |
|
| 1990 |
Weizman A, Weizman R, Kook KA, Vocci F, Deutsch SI, Paul SM. Adrenalectomy prevents the stress-induced decrease in in vivo [3H]Ro15-1788 binding to GABAA benzodiazepine receptors in the mouse. Brain Research. 519: 347-50. PMID 2168786 DOI: 10.1016/0006-8993(90)90100-P |
0.334 |
|
| 1990 |
Puia G, Santi MR, Vicini S, Pritchett DB, Purdy RH, Paul SM, Seeburg PH, Costa E. Neurosteroids act on recombinant human GABAA receptors. Neuron. 4: 759-65. PMID 2160838 DOI: 10.1016/0896-6273(90)90202-Q |
0.305 |
|
| 1990 |
Purdy RH, Morrow AL, Blinn JR, Paul SM. Synthesis, metabolism, and pharmacological activity of 3 alpha-hydroxy steroids which potentiate GABA-receptor-mediated chloride ion uptake in rat cerebral cortical synaptoneurosomes. Journal of Medicinal Chemistry. 33: 1572-81. PMID 2160534 |
0.465 |
|
| 1990 |
Morrow AL, Montpied P, Lingford-Hughes A, Paul SM. Chronic ethanol and pentobarbital administration in the rat: effects on GABAA receptor function and expression in brain. Alcohol (Fayetteville, N.Y.). 7: 237-44. PMID 2158791 DOI: 10.1016/0741-8329(90)90012-2 |
0.518 |
|
| 1990 |
Purdy RH, Moore PH, Rao PN, Hagino N, Yamaguchi T, Schmidt P, Rubinow DR, Morrow AL, Paul SM. Radioimmunoassay of 3 alpha-hydroxy-5 alpha-pregnan-20-one in rat and human plasma. Steroids. 55: 290-6. PMID 2120801 DOI: 10.1016/0039-128X(90)90031-6 |
0.455 |
|
| 1990 |
Baker BL, Morrow AL, Vergalla J, Paul SM, Jones EA. Gamma-aminobutyric acid (GABAA) receptor-function in a rat model of hepatic encephalopathy. Metabolic Brain Disease. 5: 185-93. PMID 1965008 DOI: 10.1007/BF00997072 |
0.466 |
|
| 1990 |
Morrow AL, Pace JR, Purdy RH, Paul SM. Characterization of steroid interactions with gamma-aminobutyric acid receptor-gated chloride ion channels: evidence for multiple steroid recognition sites. Molecular Pharmacology. 37: 263-70. PMID 1689453 |
0.454 |
|
| 1989 |
Miller LG, Deutsch SI, Greenblatt DJ, Paul SM, Shader RI. Acute barbiturate administration increases benzodiazepine receptor binding in vivo. Psychopharmacology. 96: 385-90. PMID 2906155 DOI: 10.1007/Bf00216067 |
0.335 |
|
| 1989 |
Montpied P, Ginns EI, Martin BM, Stetler D, O'Carroll AM, Lolait SJ, Mahan LC, Paul SM. Multiple GABAA receptor alpha subunit mRNAs revealed by developmental and regional expression in rat, chicken and human brain. Febs Letters. 258: 94-8. PMID 2556301 DOI: 10.1016/0014-5793(89)81623-0 |
0.302 |
|
| 1989 |
Drugan RC, Morrow AL, Weizman R, Weizman A, Deutsch SI, Crawley JN, Paul SM. Stress-induced behavioral depression in the rat is associated with a decrease in GABA receptor-mediated chloride ion flux and brain benzodiazepine receptor occupancy. Brain Research. 487: 45-51. PMID 2546650 DOI: 10.1016/0006-8993(89)90938-4 |
0.447 |
|
| 1988 |
Morrow AL, Paul SM. Benzodiazepine enhancement of gamma-aminobutyric acid-mediated chloride ion flux in rat brain synaptoneurosomes. Journal of Neurochemistry. 50: 302-6. PMID 3335847 DOI: 10.1111/J.1471-4159.1988.Tb13264.X |
0.478 |
|
| 1988 |
Morrow AL, Suzdak PD, Paul SM. Benzodiazepine, barbiturate, ethanol and hypnotic steroid hormone modulation of GABA-mediated chloride ion transport in rat brain synaptoneurosomes. Advances in Biochemical Psychopharmacology. 45: 247-61. PMID 2902744 |
0.428 |
|
| 1988 |
Glowa JR, Crawley J, Suzdak PD, Paul SM. Ethanol and the GABA receptor complex: Studies with the partial inverse benzodiazepine receptor agonist Ro 15-4513 Pharmacology, Biochemistry and Behavior. 31: 767-772. PMID 2855121 DOI: 10.1016/0091-3057(88)90263-8 |
0.319 |
|
| 1988 |
Morrow AL, Suzdak PD, Karanian JW, Paul SM. Chronic ethanol administration alters gamma-aminobutyric acid, pentobarbital and ethanol-mediated 36Cl- uptake in cerebral cortical synaptoneurosomes. The Journal of Pharmacology and Experimental Therapeutics. 246: 158-64. PMID 2839659 |
0.414 |
|
| 1988 |
Suzdak PD, Schwartz RD, Skolnick P, Paul SM. Alcohols stimulate gamma-aminobutyric acid receptor-mediated chloride uptake in brain vesicles: correlation with intoxication potency. Brain Research. 444: 340-5. PMID 2834024 DOI: 10.1016/0006-8993(88)90943-2 |
0.312 |
|
| 1987 |
Janowsky A, Vocci F, Berger P, Angel I, Zelnik N, Kleinman JE, Skolnick P, Paul SM. [3H]GBR-12935 binding to the dopamine transporter is decreased in the caudate nucleus in Parkinson's disease. Journal of Neurochemistry. 49: 617-21. PMID 3598589 DOI: 10.1111/J.1471-4159.1987.Tb02908.X |
0.303 |
|
| 1987 |
Luu MD, Morrow AL, Paul SM, Schwartz RD. Characterization of GABAA receptor-mediated 36chloride uptake in rat brain synaptoneurosomes. Life Sciences. 41: 1277-87. PMID 3041140 DOI: 10.1016/0024-3205(87)90207-4 |
0.515 |
|
| 1987 |
Miller LG, Thompson ML, Greenblatt DJ, Deutsch SI, Shader RI, Paul SM. Rapid increase in brain benzodiazepine receptor binding following defeat stress in mice. Brain Research. 414: 395-400. PMID 3040170 DOI: 10.1016/0006-8993(87)90023-0 |
0.34 |
|
| 1987 |
Miller LG, Greenblatt DJ, Barnhill JG, Deutsch SI, Shader RI, Paul SM. Benzodiazepine receptor binding of triazolobenzodiazepines in vivo: Increased receptor number with low-dose alprazolam Journal of Neurochemistry. 49: 1595-1601. PMID 2889803 DOI: 10.1111/J.1471-4159.1987.Tb01032.X |
0.328 |
|
| 1987 |
Labarca R, Janowsky A, Paul SM. Neurotransmitter-stimulated inositol phosphate accumulation in hippocampal slices. Methods in Enzymology. 141: 192-201. PMID 2885715 DOI: 10.1016/0076-6879(87)41067-7 |
0.34 |
|
| 1987 |
Morrow AL, Suzdak PD, Paul SM. Steroid hormone metabolites potentiate GABA receptor-mediated chloride ion flux with nanomolar potency. European Journal of Pharmacology. 142: 483-5. PMID 2828079 DOI: 10.1016/0014-2999(87)90094-X |
0.489 |
|
| 1987 |
Schwartz RD, Wess MJ, Labarca R, Skolnick P, Paul SM. Acute stress enhances the activity of the GABA receptor-gated chloride ion channel in brain. Brain Research. 411: 151-5. PMID 2440512 DOI: 10.1016/0006-8993(87)90692-5 |
0.314 |
|
| 1986 |
Janowsky A, Berger P, Vocci F, Labarca R, Skolnick P, Paul SM. Characterization of sodium-dependent [3H]GBR-12935 binding in brain: a radioligand for selective labelling of the dopamine transport complex. Journal of Neurochemistry. 46: 1272-6. PMID 3081686 DOI: 10.1111/J.1471-4159.1986.Tb00649.X |
0.301 |
|
| 1986 |
Suzdak PD, Glowa JR, Crawley JN, Schwartz RD, Skolnick P, Paul SM. A selective imidazobenzodiazepine antagonist of ethanol in the rat Science. 234: 1243-1247. PMID 3022383 DOI: 10.1126/Science.3022383 |
0.31 |
|
| 1986 |
Suzdak PD, Schwartz RD, Skolnick P, Paul SM. Ethanol stimulates gamma-aminobutyric acid receptor-mediated chloride transport in rat brain synaptoneurosomes. Proceedings of the National Academy of Sciences of the United States of America. 83: 4071-5. PMID 2424017 DOI: 10.1073/Pnas.83.11.4071 |
0.303 |
|
| 1986 |
Majewska MD, Harrison NL, Schwartz RD, Barker JL, Paul SM. Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor. Science (New York, N.Y.). 232: 1004-7. PMID 2422758 DOI: 10.1126/Science.2422758 |
0.328 |
|
| 1986 |
Hommer D, Stoner G, Crawley J, Paul S, Skirboll L. Cholecystokinin-dopamine coexistence: electrophysiological actions corresponding to cholecystokinin receptor subtype The Journal of Neuroscience. 6: 3039-3043. DOI: 10.1523/Jneurosci.06-10-03039.1986 |
0.3 |
|
| 1985 |
Ruff MR, Pert CB, Weber RJ, Wahl LM, Wahl SM, Paul SM. Benzodiazepine receptor-mediated chemotaxis of human monocytes. Science (New York, N.Y.). 229: 1281-3. PMID 2994216 DOI: 10.1126/Science.2994216 |
0.325 |
|
| 1985 |
Schwartz R, Jackson J, Weigert D, Skolnick P, Paul S. Characterization of barbiturate-stimulated chloride efflux from rat brain synaptoneurosomes The Journal of Neuroscience. 5: 2963-2970. DOI: 10.1523/Jneurosci.05-11-02963.1985 |
0.317 |
|
| 1984 |
Insel TR, Ninan PT, Aloi J, Jimerson DC, Skolnick P, Paul SM. A benzodiazepine receptor-mediated model of anxiety. Studies in nonhuman primates and clinical implications. Archives of General Psychiatry. 41: 741-50. PMID 6331336 DOI: 10.1001/Archpsyc.1984.01790190015002 |
0.321 |
|
| 1984 |
Guzman F, Cain M, Larscheid P, Hagen T, Cook JM, Schweri M, Skolnick P, Paul SM. Biomimetic approach to potential benzodiazepine receptor agonists and antagonists. Journal of Medicinal Chemistry. 27: 564-70. PMID 6325688 DOI: 10.1002/Chin.198443191 |
0.313 |
|
| 1984 |
Crawley JN, Skolnic P, Paul SM. Absence of intrinsic antagonist actions of benzodiazepine antagonists on an exploratory model of anxiety in the mouse Neuropharmacology. 23: 531-537. PMID 6146107 DOI: 10.1016/0028-3908(84)90026-1 |
0.311 |
|
| 1984 |
Skolnick P, Ninan P, Insel T, Crawley J, Paul S. A novel chemically induced animal model of human anxiety. Psychopathology. 25-36. PMID 6143342 DOI: 10.1159/000284074 |
0.316 |
|
| 1984 |
Janowsky A, Labarca R, Paul SM. Characterization of neurotransmitter receptor-mediated phosphatidylinositol hydrolysis in the rat hippocampus. Life Sciences. 35: 1953-61. PMID 6092808 DOI: 10.1016/0024-3205(84)90476-4 |
0.344 |
|
| 1983 |
Skolnick P, Paul S, Crawley J, Lewin E, Lippa A, Clody D, Irmscher K, Saiko O, Minck KO. Antagonism of the anxiolytic action of diazepam and chlordiazepoxide by the novel imidazopyridines, EMD 39593 and EMD 41717. European Journal of Pharmacology. 88: 319-27. PMID 6688050 DOI: 10.1016/0014-2999(83)90582-4 |
0.3 |
|
| 1983 |
Ninan PT, Insel TM, Cohen RM, Cook JM, Skolnick P, Paul SM. Benzodiazepine receptor-mediated experimental "anxiety" in primates. Science (New York, N.Y.). 218: 1332-4. PMID 6293059 DOI: 10.1126/Science.6293059 |
0.338 |
|
| 1983 |
Hauger RL, Paul SM. Neurotransmitter Receptor Plasticity: Alterations by Antidepressants and Antipsychotics Psychiatric Annals. 13: 399-407. DOI: 10.3928/0048-5713-19830501-04 |
0.301 |
|
| 1982 |
Paul SM, Hulihan-Giblin B, Skolnick P. (+)-Amphetamine binding to rat hypothalamus: Relation to anorexic potency of phenylethylamines Science. 218: 487-490. PMID 7123250 DOI: 10.1126/Science.7123250 |
0.306 |
|
| 1982 |
Skolnick P, Rice KC, Barker JL, Paul SM. Interaction of barbiturates with benzodiazepine receptors in the central nervous system. Brain Research. 233: 143-56. PMID 6277423 DOI: 10.1016/0006-8993(82)90936-2 |
0.346 |
|
| 1981 |
Marangos PJ, Patel J, Hirata F, Sondhein D, Paul SM, Skolnick P, Goodwin FK. Inhibition of diazepam binding by tryptophan derivatives including melatonin and its brain metabolite N-acetyl-5-methoxy kynurenamine. Life Sciences. 29: 259-67. PMID 7289793 DOI: 10.1016/0024-3205(81)90242-3 |
0.333 |
|
| 1981 |
Hays SE, Goodwin FK, Paul SM. Cholecystokinin receptors are decreased in basal ganglia and cerebral cortex of Huntington's disease. Brain Research. 225: 452-6. PMID 6272931 DOI: 10.1016/0006-8993(81)90853-2 |
0.3 |
|
| 1981 |
Hays SE, Goodwin FK, Paul SM. Cholecystokinin receptors in brain: effects of obesity, drug treatment, and lesions. Peptides. 2: 21-6. PMID 6267558 DOI: 10.1016/0196-9781(81)90051-6 |
0.338 |
|
| 1981 |
Hays SE, Meyer DK, Paul SM. Localization of cholecystokinin receptors on neuronal elements in rat caudate nucleus. Brain Research. 219: 208-13. PMID 6266600 DOI: 10.1016/0006-8993(81)90284-5 |
0.323 |
|
| 1981 |
Crews FT, Paul SM, Goodwin FK. Acceleration of beta-receptor desensitization in combined administration of antidepressants and phenoxybenzamine. Nature. 290: 787-9. PMID 6261156 DOI: 10.1038/290787A0 |
0.335 |
|
| 1981 |
Skolnick P, Moncada V, Barker JL, Paul SM. Pentobarbital: dual actions to increase brain benzodiazepine receptor affinity. Science (New York, N.Y.). 211: 1448-50. PMID 6258230 DOI: 10.1126/Science.6258230 |
0.356 |
|
| 1980 |
Rehavi M, Paul SM, Skolnick P, Goodwin FK. Demonstration of specific high affinity binding sites for [3H] imipramine in human brain. Life Sciences. 26: 2273-9. PMID 7401921 DOI: 10.1016/0024-3205(80)90213-1 |
0.303 |
|
| 1980 |
Paul SM, Crews FT. Rapid desensitization of cerebral cortical beta-adrenergic receptors induced by desmethylimipramine and phenoxybenzamine. European Journal of Pharmacology. 62: 349-50. PMID 6245899 DOI: 10.1016/0014-2999(80)90104-1 |
0.305 |
|
| 1980 |
Tallman JF, Paul SM, Skolnick P, Gallager DW. Receptors for the age of anxiety: pharmacology of the benzodiazepines. Science (New York, N.Y.). 207: 274-81. PMID 6101294 DOI: 10.1126/Science.6101294 |
0.335 |
|
| 1980 |
Hays SE, Beinfeld MC, Jensen RT, Goodwin FK, Paul SM. Demonstration of a putative receptor site for cholecystokinin in rat brain Neuropeptides. 1: 53-62. DOI: 10.1016/0143-4179(80)90009-8 |
0.309 |
|
| 1979 |
Skolnick P, Paul SM, Marangos PJ. Brain benzodiazepine levels following intravenous administration of [3H]diazepam: relationship to the potentiation of purinergic depression of central nervous system neurons Canadian Journal of Physiology and Pharmacology. 57: 1040-1042. PMID 519536 DOI: 10.1139/Y79-157 |
0.322 |
|
| 1979 |
Marangos PJ, Paul SM, Goodwin FK, Skolnick P. Putative endogenous ligands for the benzodiazepine receptor. Life Sciences. 25: 1093-102. PMID 390284 DOI: 10.1016/0024-3205(79)90130-9 |
0.345 |
|
| 1979 |
Skolnick P, Syapin PJ, Paugh BA, Moncada V, Marangos PJ, Paul SM. Inosine, an endogenous ligand of the brain benzodiazepine receptor, antagonizes pentylenetetrazole-evoked seizures. Proceedings of the National Academy of Sciences of the United States of America. 76: 1515-8. PMID 286337 DOI: 10.1073/Pnas.76.3.1515 |
0.321 |
|
| 1979 |
Skolnick P, Syapin PJ, Paugh BA, Paul SM. Reduction in benzodiazepine receptors associated with Purkinje cell degeneration in ‘nervous’ mutant mice Nature. 277: 397-399. PMID 233119 DOI: 10.1038/277397A0 |
0.328 |
|
| 1979 |
Skolnick P, Marangos PJ, Syapin P, Goodwin FK, Paul SM. CNS benzodiazepine receptors: physiological studies and putative endogenous ligands. Pharmacology, Biochemistry, and Behavior. 10: 815-23. PMID 40256 DOI: 10.1016/0091-3057(79)90340-X |
0.335 |
|
| 1979 |
RICE KC, BROSSI A, TALLMAN J, PAUL SM, SKOLNICK P. ChemInform Abstract: IRAZEPINE, A NONCOMPETITIVE, IRREVERSIBLE INHIBITOR OF 3H-DIAZEPAM BINDING TO BENZODIAZEPINE RECEPTORS Chemischer Informationsdienst. 10. DOI: 10.1002/Chin.197930382 |
0.301 |
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