Xiaojiang Chen - Publications

Affiliations: 
Genetic, Molecular, and Cell Biology University of Southern California, Los Angeles, CA, United States 
Area:
Biochemistry
Website:
https://dornsife.usc.edu/cf/faculty-and-staff/faculty.cfm?pid=1003163

98 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kim K, Shi AB, Kelley K, Chen XS. Unraveling the Enzyme-Substrate Properties for APOBEC3A-mediated RNA Editing. Journal of Molecular Biology. 168198. PMID 37442413 DOI: 10.1016/j.jmb.2023.168198  0.696
2023 Ito F, Alvarez-Cabrera AL, Liu S, Yang H, Shiriaeva A, Zhou ZH, Chen XS. Structural basis for HIV-1 antagonism of host APOBEC3G via Cullin E3 ligase. Science Advances. 9: eade3168. PMID 36598981 DOI: 10.1126/sciadv.ade3168  0.64
2022 Yang H, Kim K, Li S, Pacheco J, Chen XS. Structural basis of sequence-specific RNA recognition by the antiviral factor APOBEC3G. Nature Communications. 13: 7498. PMID 36470880 DOI: 10.1038/s41467-022-35201-9  0.718
2022 Kim K, Calabrese P, Wang S, Qin C, Rao Y, Feng P, Chen XS. The roles of APOBEC-mediated RNA editing in SARS-CoV-2 mutations, replication and fitness. Scientific Reports. 12: 14972. PMID 36100631 DOI: 10.1038/s41598-022-19067-x  0.705
2022 Kim K, Calabrese P, Wang S, Qin C, Rao Y, Feng P, Chen XS. The Roles of APOBEC-mediated RNA Editing in SARS-CoV-2 Mutations, Replication and Fitness. Research Square. PMID 35441170 DOI: 10.21203/rs.3.rs-1524060/v1  0.705
2021 Kim K, Calabrese P, Wang S, Qin C, Rao Y, Feng P, Chen XS. APOBEC-mediated Editing of SARS-CoV-2 Genomic RNA Impacts Viral Replication and Fitness. Biorxiv : the Preprint Server For Biology. PMID 34981048 DOI: 10.1101/2021.12.18.473309  0.701
2020 Wolfe AD, Li S, Goedderz C, Chen XS. The structure of APOBEC1 and insights into its RNA and DNA substrate selectivity. Nar Cancer. 2: zcaa027. PMID 33094286 DOI: 10.1093/narcan/zcaa027  0.745
2020 Baumert R, Ji H, Paulucci-Holthauzen A, Wolfe A, Sagum C, Hodgson L, Arikkath J, Chen X, Bedford MT, Waxham MN, McCrea PD. Novel phospho-switch function of delta-catenin in dendrite development. The Journal of Cell Biology. 219. PMID 33007084 DOI: 10.1083/jcb.201909166  0.673
2020 Yang H, Ito F, Wolfe AD, Li S, Mohammadzadeh N, Love RP, Yan M, Zirkle B, Gaba A, Chelico L, Chen XS. Understanding the structural basis of HIV-1 restriction by the full length double-domain APOBEC3G. Nature Communications. 11: 632. PMID 32005813 DOI: 10.1038/s41467-020-14377-y  0.796
2019 Gai D, Wang D, Li SX, Chen XS. Retraction: The structure of SV40 large T hexameric helicase in complex with AT-rich origin DNA. Elife. 8. PMID 30942691 DOI: 10.7554/eLife.46910  0.776
2019 Wolfe AD, Arnold DB, Chen X. Comparison of RNA Editing Activity of APOBEC1-A1CF and APOBEC1-RBM47 Complexes Reconstituted in HEK293T Cells. Journal of Molecular Biology. PMID 30844405 DOI: 10.1016/j.jmb.2019.02.025  0.691
2018 Ito F, Yang H, Xiao X, Li SX, Wolfe A, Zirkle B, Arutiunian V, Chen XS. Understanding the Structure, Multimerization, Subcellular Localization and mC Selectivity of a Genomic Mutator and Anti-HIV Factor APOBEC3H. Scientific Reports. 8: 3763. PMID 29491387 DOI: 10.1038/s41598-018-21955-0  0.808
2017 Fang Y, Xiao X, Li SX, Wolfe A, Chen XS. Molecular Interactions of a DNA Modifying Enzyme APOBEC3F Catalytic Domain with a Single-Stranded DNA. Journal of Molecular Biology. PMID 29191651 DOI: 10.1016/j.jmb.2017.11.007  0.758
2017 Ning T, Wolfe A, Nie J, Huang W, Chen XS, Wang Y. Naturally Occurring Single Amino Acid Substitution in the L1 Major Capsid Protein of Human Papillomavirus Type 16: Alteration of Susceptibility to Antibody-Mediated Neutralization. The Journal of Infectious Diseases. PMID 28968823 DOI: 10.1093/infdis/jix274  0.657
2017 Xiao X, Yang H, Arutiunian V, Fang Y, Besse G, Morimoto C, Zirkle B, Chen XS. Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation. Nucleic Acids Research. PMID 28645149 DOI: 10.1093/nar/gkx564  0.364
2017 Xiao X, Yang H, Arutiunian V, Fang Y, Besse G, Morimoto C, Zirkle B, Chen XS. Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation. Nucleic Acids Research. PMID 28575276 DOI: 10.1093/nar/gkx362  0.419
2017 Ito F, Fu Y, Kao SA, Yang H, Chen XS. Family-Wide Comparative Analysis of Cytidine and Methylcytidine Deamination by Eleven Human APOBEC Proteins. Journal of Molecular Biology. PMID 28479091 DOI: 10.1016/j.jmb.2017.04.021  0.651
2017 Wang D, Álvarez-Cabrera AL, Chen XS. Study of SV40 large T antigen nucleotide specificity for DNA unwinding. Virology Journal. 14: 79. PMID 28410592 DOI: 10.1186/s12985-017-0733-5  0.795
2016 Gai D, Wang D, Li SX, Chen XS. The structure of SV40 large T hexameric helicase in complex with AT-rich origin DNA. Elife. 5. PMID 27921994 DOI: 10.7554/eLife.18129  0.799
2016 Gu J, Chen Q, Xiao X, Ito F, Wolfe A, Chen XS. Biochemical Characterization of APOBEC3H Variants: Implications for Their HIV-1 Restriction Activity and mC Modification. Journal of Molecular Biology. PMID 27534815 DOI: 10.1016/j.jmb.2016.08.012  0.787
2016 Sun X, Liu S, Chen P, Fu D, Hou Y, Hu J, Liu Z, Jiang Y, Cao X, Cheng C, Chen X, Tao Y, Li C, Hu Y, Liu Z, et al. miR-449a inhibits colorectal cancer progression by targeting SATB2. Oncotarget. PMID 27486765 DOI: 10.18632/oncotarget.10900  0.423
2016 Xiao X, Li SX, Yang H, Chen XS. Crystal structures of APOBEC3G N-domain alone and its complex with DNA. Nature Communications. 7: 12193. PMID 27480941 DOI: 10.1038/ncomms12193  0.443
2016 Chen X, Lai Y, Chen X, Shi Y, Zhu D. A novel spectral multivariate calibration approach based on a multiple fitting method. The Analyst. PMID 27478887 DOI: 10.1039/c6an01201a  0.425
2016 Lu BR, Ma MZ, Gao F, Shi YH, Chen XR. Morphology and molecular phylogeny of two colepid species from China, Coleps amphacanthus Ehrenberg, 1833 and Levicoleps biwae jejuensis Chen et al., 2016 (Ciliophora, Prostomatida). Dong Wu Xue Yan Jiu = Zoological Research / "Dong Wu Xue Yan Jiu" Bian Ji Wei Yuan Hui Bian Ji. 37: 176-185. PMID 27265656  0.431
2016 Chen X, Zhao M, Shi Y, Yang L, Lu Y, Huang Z. Visual outcomes and optical quality after implantation of a diffractive multifocal toric intraocular lens. Indian Journal of Ophthalmology. 64: 285-91. PMID 27221680 DOI: 10.4103/0301-4738.182939  0.4
2016 Ye Y, Hu X, Shi Y, Zhou J, Zhou Y, Song X, Xie Y, Lu X, Wang L, Ying B, Chen X. Clinical Features and Drug-Resistance Profile of Urinary Tuberculosis in South-Western China: A Cross-sectional Study. Medicine. 95: e3537. PMID 27175652 DOI: 10.1097/MD.0000000000003537  0.443
2016 Ma Y, Zhang Y, Gu Y, Chen X, Shi Y, Ji W, Xi S, Du B, Li X, Tang H, Li Y, Fang J. Impact of etching on the surface leakage generation in mesa-type InGaAs/InAlAs avalanche photodetectors. Optics Express. 24: 7823-7834. PMID 27137065  0.42
2016 Liu Y, Chen X, Bian Q, Shi Y, Liu Q, Ding L, Zhang H, Zhu B. Analysis of plasma microRNA expression profiles in a Chinese population occupationally exposed to benzene and in a population with chronic benzene poisoning. Journal of Thoracic Disease. 8: 403-14. PMID 27076935 DOI: 10.21037/jtd.2016.02.56  0.404
2016 Yang Q, Chen X, Zheng T, Han D, Zhang H, Shi Y, Bian J, Sun X, Xia K, Liang X, Liu G, Zhang Y, Deng C. Transplantation of human urine-derived stem cells transfected with pigment epithelium-derived factor to protect erectile function in a rat model of cavernous nerve injury. Cell Transplantation. PMID 27075964 DOI: 10.3727/096368916X691448  0.433
2016 Chen Q, Xiao X, Wolfe A, Chen XS. The in vitro Biochemical Characterization of an HIV-1 Restriction Factor A3F: Importance of loop 7 on both CD1 and CD2 for DNA binding and deamination. Journal of Molecular Biology. PMID 27063502 DOI: 10.1016/j.jmb.2016.03.031  0.726
2016 Xin C, Chen X, Shi Y, Li M, Wang H, Wang N. One-year interim comparison of canaloplasty in primary open-angle glaucoma following failed filtering surgery with primary canaloplasty. The British Journal of Ophthalmology. PMID 27060163 DOI: 10.1136/bjophthalmol-2015-308219  0.413
2016 Shi Y, Tu H, Chen X, Zhang Y, Chen L, Liu Z, Sheng J, Han S, Yin J, Peng B, He X, Liu W. The long non-coding RNA expression profile of Coxsackievirus A16 infected RD cells identified by RNA-seq. Virologica Sinica. PMID 27060091 DOI: 10.1007/S12250-015-3693-1  0.49
2016 Xin C, Chen X, Shi Y, Wang H, Wang N. Modified Canaloplasty: A New, Effective, and Safe Option for Glaucoma Patients With a Disrupted Schlemm Canal Wall. Journal of Glaucoma. PMID 27027226 DOI: 10.1097/IJG.0000000000000420  0.419
2016 Yi TY, Chen WH, Zhang MF, Chen YH, Cai RW, Wu ZZ, Wu YM, Shi YC, Chen BL, Guo TH, Wu CX, Yang MX, Chen XJ. Diagnostic ability of 3-dimensional contrast-enhanced MR angiography in identifying vertebral basilar artery stenosis. Journal of the Neurological Sciences. 363: 121-5. PMID 27000236 DOI: 10.1016/j.jns.2016.02.013  0.409
2016 Song H, Qi J, Khedri Z, Diaz S, Yu H, Chen X, Varki A, Shi Y, Gao GF. Correction: An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism. Plos Pathogens. 12: e1005505. PMID 26954772 DOI: 10.1371/journal.ppat.1005505  0.468
2016 Xu F, Kang T, Deng J, Liu J, Chen X, Wang Y, Ouyang L, Du T, Tang H, Xu X, Chen S, Du Y, Shi Y, Qian Z, Wei Y, et al. Functional Nanoparticles Activate a Decellularized Liver Scaffold for Blood Detoxification. Small (Weinheim An Der Bergstrasse, Germany). PMID 26914158 DOI: 10.1002/Smll.201503320  0.421
2016 Shi Y, Chen X, Elsasser S, Stocks BB, Tian G, Lee BH, Shi Y, Zhang N, de Poot SA, Tuebing F, Sun S, Vannoy J, Tarasov SG, Engen JR, Finley D, et al. Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome. Science (New York, N.Y.). 351. PMID 26912900 DOI: 10.1126/Science.Aad9421  0.493
2016 Zhang Z, Hu F, Liu Y, Ma B, Chen X, Zhu K, Shi Y, Wei T, Xing Y, Gao Y, Lu H, Liu Y, Kang Q. Activation of type 5 metabotropic glutamate receptor promotes the proliferation of rat retinal progenitor cell via activation of the PI-3-K and MAPK signaling pathways. Neuroscience. PMID 26902516 DOI: 10.1016/J.Neuroscience.2016.02.030  0.441
2016 Quan Z, Huang B, Lu C, Shi Y, Chen X, Zhang H, Fang Y. The fate of fertilizer nitrogen in a high nitrate accumulated agricultural soil. Scientific Reports. 5: 21539. PMID 26868028 DOI: 10.1038/srep21539  0.419
2016 Chen X, Zhang Y, Shi Y, Lian H, Tu H, Han S, Yin J, Peng B, Zhou B, He X, Liu W. MiR-129 triggers autophagic flux by regulating a novel Notch-1/ E2F7/Beclin-1 axis to impair the viability of human malignant glioma cells. Oncotarget. PMID 26824182 DOI: 10.18632/Oncotarget.7003  0.42
2016 Song H, Qi J, Khedri Z, Diaz S, Yu H, Chen X, Varki A, Shi Y, Gao GF. An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism. Plos Pathogens. 12: e1005411. PMID 26816272 DOI: 10.1371/Journal.Ppat.1005411  0.509
2016 Shi Y, Peng SL, Yang LF, Chen X, Tao YG, Cao Y. Co-infection of Epstein-Barr virus and human papillomavirus in human tumorigenesis. Chinese Journal of Cancer. 35: 16. PMID 26801987 DOI: 10.1186/s40880-016-0079-1  0.472
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... Chen X, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.454
2016 Chen X, Yang Q, Zheng T, Bian J, Sun X, Shi Y, Liang X, Gao G, Liu G, Deng C. Neurotrophic Effect of Adipose Tissue-Derived Stem Cells on Erectile Function Recovery by Pigment Epithelium-Derived Factor Secretion in a Rat Model of Cavernous Nerve Injury. Stem Cells International. 2016: 5161248. PMID 26783403 DOI: 10.1155/2016/5161248  0.428
2016 Velletri T, Xie N, Wang Y, Huang Y, Yang Q, Chen X, Chen Q, Shou P, Gan Y, Cao G, Melino G, Shi Y. P53 functional abnormality in mesenchymal stem cells promotes osteosarcoma development. Cell Death & Disease. 7: e2015. PMID 26775693 DOI: 10.1038/Cddis.2015.367  0.441
2015 Shi Y, Chung JM, Cheng JT, Tracy JL, Robins RW, Chen X, Zheng Y. Cross-cultural evidence for the two-facet structure of pride. Journal of Research in Personality. 55: 61-74. PMID 27158171 DOI: 10.1016/J.Jrp.2015.01.004  0.453
2015 Chen X, Shi YD, Tie L. [Rho-associated protein kinase: significant role in diabetic complications]. Sheng Li Ke Xue Jin Zhan [Progress in Physiology]. 46: 433-8. PMID 27089689  0.424
2015 Shi Y, Guo J, Zhang W, Jin L, Liu P, Chen X, Li F, Wei P, Li Z, Li W, Wei C, Zheng Q, Chen Q, Zhang J, Lin F, et al. Cloning of the Lycopene β-cyclase Gene in Nicotiana tabacum and Its Overexpression Confers Salt and Drought Tolerance. International Journal of Molecular Sciences. 16: 30438-57. PMID 26703579 DOI: 10.3390/ijms161226243  0.429
2015 Shi Y, Wang H, Yin J, Li M, Zhang X, Xin C, Chen X, Wang N. Microcatheter-assisted trabeculotomy versus rigid probe trabeculotomy in childhood glaucoma. The British Journal of Ophthalmology. PMID 26674778 DOI: 10.1136/Bjophthalmol-2015-307880  0.412
2015 Xu X, Yu T, Xu R, Shi Y, Lin X, Xu Q, Qi X, Weng Y, Chen X. Fine mapping of a dominantly inherited powdery mildew resistance major-effect QTL, Pm1.1, in cucumber identifies a 41.1 kb region containing two tandemly arrayed cysteine-rich receptor-like protein kinase genes. Tag. Theoretical and Applied Genetics. Theoretische Und Angewandte Genetik. PMID 26660669 DOI: 10.1007/s00122-015-2644-4  0.438
2015 Li Y, Dong W, Shi Y, Deng F, Chen X, Wan C, Zhou M, Zhao L, Fu ZF, Peng G. Rabies virus phosphoprotein interacts with ribosomal protein L9 and affects rabies virus replication. Virology. 488: 216-224. PMID 26655239 DOI: 10.1016/j.virol.2015.11.018  0.512
2015 Lin N, Chen LM, Pan XD, Zhu YG, Zhang J, Shi YQ, Chen XC. Tripchlorolide Attenuates β-amyloid Generation via Suppressing PPARγ-Regulated BACE1 Activity in N2a/APP695 Cells. Molecular Neurobiology. PMID 26582466 DOI: 10.1007/S12035-015-9542-2  0.469
2015 Shi YS, Li L, Liu YB, Ma SG, Li Y, Qu J, Liu Q, Shen ZF, Chen XG, Yu SS. A new thiophene and two new monoterpenoids from Xanthium sibiricum. Journal of Asian Natural Products Research. 1-9. PMID 26466199 DOI: 10.1080/10286020.2015.1070146  0.433
2015 Xia J, Chen X, Xu F, Wang Y, Shi Y, Li Y, He J, Zhang P. Dengue virus infection induces formation of G3BP1 granules in human lung epithelial cells. Archives of Virology. PMID 26350772 DOI: 10.1007/s00705-015-2578-9  0.492
2015 Li T, Sheng J, Li W, Zhang X, Yu H, Chen X, Zhang J, Cai Q, Shi Y, Liu Z. A new computational model for human thyroid cancer enhances the preoperative diagnostic efficacy. Oncotarget. PMID 26325368  0.42
2015 Chen X, Zhang Y, Shi Y, Lian H, Tu H, Han S, Peng B, Liu W, He X. miR-873 acts as a novel sensitizer of glioma cells to cisplatin by targeting Bcl-2. International Journal of Oncology. PMID 26323558 DOI: 10.3892/Ijo.2015.3143  0.43
2015 Shi Y, Chen YH, Yin XJ, Wang AQ, Chen XK, Lu JH, Ji R, Bao CH, Sun J, Zhao JM, Wu HG. Electroacupuncture versus Moxibustion for Irritable Bowel Syndrome: A Randomized, Parallel-Controlled Trial. Evidence-Based Complementary and Alternative Medicine : Ecam. 2015: 361786. PMID 26294923 DOI: 10.1155/2015/361786  0.407
2015 Shi Y, Matsunaga T, Saito M, Yamaguchi Y, Chen X. Comparison of global inventories of CO2 emissions from biomass burning during 2002-2011 derived from multiple satellite products. Environmental Pollution (Barking, Essex : 1987). 206: 479-87. PMID 26281761 DOI: 10.1016/j.envpol.2015.08.009  0.399
2015 Chen X, Shi YM, Huang C, Xia S, Yang LJ, Yang XD. Novel dibenzo[b,d]furan-1H-1,2,4-triazole derivatives: Synthesis and antitumor activity. Anti-Cancer Agents in Medicinal Chemistry. PMID 26278547  0.43
2015 Shi Y, Xing P, Fan Y, Zhang X, Hu C, Wang C, Liu X, Chen X, Zhou J, Wang M, Wu M, Han B, Fan M. Current small cell lung cancer treatment in China. Thoracic Cancer. 6: 233-8. PMID 26273367 DOI: 10.1111/1759-7714.12218  0.412
2015 Fu Y, Ito F, Zhang G, Fernandez B, Yang H, Chen XS. DNA Cytosine and Methylcytosine Deamination by APOBEC3B: Enhancing Methylcytosine Deamination by Engineering APOBEC3B. The Biochemical Journal. PMID 26195824 DOI: 10.1042/BJ20150382  0.663
2015 Yu XJ, Greenleaf WB, Shi YS, Chen XS. Mechanism of subunit coordination of an AAA+ hexameric molecular nanomachine. Nanomedicine : Nanotechnology, Biology, and Medicine. 11: 531-41. PMID 25555349 DOI: 10.1016/j.nano.2014.11.005  0.563
2014 Fu Y, Slaymaker IM, Wang J, Wang G, Chen XS. The 1.8-Å crystal structure of the N-terminal domain of an archaeal MCM as a right-handed filament. Journal of Molecular Biology. 426: 1512-23. PMID 24378617 DOI: 10.1016/J.Jmb.2013.12.025  0.776
2013 Schmitt K, Guo K, Katuwal M, Wilson D, Prochnow C, Bransteitter R, Chen XS, Santiago ML, Stephens EB. Lentivirus restriction by diverse primate APOBEC3A proteins. Virology. 442: 82-96. PMID 23648232 DOI: 10.1016/J.Virol.2013.04.002  0.763
2013 Chang YP, Xu M, Machado AC, Yu XJ, Rohs R, Chen XS. Mechanism of origin DNA recognition and assembly of an initiator-helicase complex by SV40 large tumor antigen. Cell Reports. 3: 1117-27. PMID 23545501 DOI: 10.1016/j.celrep.2013.03.002  0.484
2013 Xu M, Chang YP, Chen XS. Expression, purification and biochemical characterization of Schizosaccharomyces pombe Mcm4, 6 and 7. Bmc Biochemistry. 14: 5. PMID 23444842 DOI: 10.1186/1471-2091-14-5  0.464
2013 Wang W, Nie J, Prochnow C, Truong C, Jia Z, Wang S, Chen XS, Wang Y. A systematic study of the N-glycosylation sites of HIV-1 envelope protein on infectivity and antibody-mediated neutralization. Retrovirology. 10: 14. PMID 23384254 DOI: 10.1186/1742-4690-10-14  0.736
2013 Slaymaker IM, Fu Y, Toso DB, Ranatunga N, Brewster A, Forsburg SL, Zhou ZH, Chen XS. Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology. Nucleic Acids Research. 41: 3446-56. PMID 23361460 DOI: 10.1093/Nar/Gkt022  0.807
2012 Slaymaker IM, Chen XS. MCM structure and mechanics: what we have learned from archaeal MCM. Sub-Cellular Biochemistry. 62: 89-111. PMID 22918582 DOI: 10.1007/978-94-007-4572-8_6  0.764
2012 Mu Y, Prochnow C, Pham P, Chen XS, Goodman MF. A structural basis for the biochemical behavior of activation-induced deoxycytidine deaminase class-switch recombination-defective hyper-IgM-2 mutants. The Journal of Biological Chemistry. 287: 28007-16. PMID 22715099 DOI: 10.1074/Jbc.M112.370189  0.781
2012 Zhou B, Arnett DR, Yu X, Brewster A, Sowd GA, Xie CL, Vila S, Gai D, Fanning E, Chen XS. Structural basis for the interaction of a hexameric replicative helicase with the regulatory subunit of human DNA polymerase α-primase. The Journal of Biological Chemistry. 287: 26854-66. PMID 22700977 DOI: 10.1074/Jbc.M112.363655  0.707
2010 Brewster AS, Slaymaker IM, Afif SA, Chen XS. Mutational analysis of an archaeal minichromosome maintenance protein exterior hairpin reveals critical residues for helicase activity and DNA binding. Bmc Molecular Biology. 11: 62. PMID 20716382 DOI: 10.1186/1471-2199-11-62  0.804
2010 Brewster AS, Chen XS. Insights into the MCM functional mechanism: lessons learned from the archaeal MCM complex. Critical Reviews in Biochemistry and Molecular Biology. 45: 243-56. PMID 20441442 DOI: 10.3109/10409238.2010.484836  0.634
2010 Cuesta I, Núñez-Ramírez R, Scheres SH, Gai D, Chen XS, Fanning E, Carazo JM. Conformational rearrangements of SV40 large T antigen during early replication events. Journal of Molecular Biology. 397: 1276-86. PMID 20219473 DOI: 10.1016/J.Jmb.2010.02.042  0.34
2010 Chelico L, Prochnow C, Erie DA, Chen XS, Goodman MF. Structural model for deoxycytidine deamination mechanisms of the HIV-1 inactivation enzyme APOBEC3G. The Journal of Biological Chemistry. 285: 16195-205. PMID 20212048 DOI: 10.1074/Jbc.M110.107987  0.797
2009 Prochnow C, Bransteitter R, Chen XS. APOBEC deaminases-mutases with defensive roles for immunity. Science in China. Series C, Life Sciences / Chinese Academy of Sciences. 52: 893-902. PMID 19911124 DOI: 10.1007/S11427-009-0133-1  0.773
2009 Shi Y, Liu H, Gai D, Ma J, Chen XS. A computational analysis of ATP binding of SV40 large tumor antigen helicase motor. Plos Computational Biology. 5: e1000514. PMID 19779548 DOI: 10.1371/Journal.Pcbi.1000514  0.513
2009 Bransteitter R, Prochnow C, Chen XS. The current structural and functional understanding of APOBEC deaminases. Cellular and Molecular Life Sciences : Cmls. 66: 3137-47. PMID 19547914 DOI: 10.1007/S00018-009-0070-Y  0.775
2009 Liu H, Shi Y, Chen XS, Warshel A. Simulating the electrostatic guidance of the vectorial translocations in hexameric helicases and translocases. Proceedings of the National Academy of Sciences of the United States of America. 106: 7449-54. PMID 19383795 DOI: 10.1073/Pnas.0900532106  0.537
2009 Tsai SJ, Sen U, Zhao L, Greenleaf WB, Dasgupta J, Fiorillo E, Orrú V, Bottini N, Chen XS. Crystal structure of the human lymphoid tyrosine phosphatase catalytic domain: insights into redox regulation . Biochemistry. 48: 4838-45. PMID 19371084 DOI: 10.1021/Bi900166Y  0.557
2009 Orrú V, Tsai SJ, Rueda B, Fiorillo E, Stanford SM, Dasgupta J, Hartiala J, Zhao L, Ortego-Centeno N, D'Alfonso S, Arnett FC, Wu H, Gonzalez-Gay MA, Tsao BP, ... ... Chen XS, et al. A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus. Human Molecular Genetics. 18: 569-79. PMID 18981062 DOI: 10.1093/Hmg/Ddn363  0.496
2008 Brewster AS, Wang G, Yu X, Greenleaf WB, Carazo JM, Tjajadi M, Klein MG, Chen XS. Crystal structure of a near-full-length archaeal MCM: functional insights for an AAA+ hexameric helicase. Proceedings of the National Academy of Sciences of the United States of America. 105: 20191-6. PMID 19073923 DOI: 10.1073/Pnas.0808037105  0.658
2008 Holden LG, Prochnow C, Chang YP, Bransteitter R, Chelico L, Sen U, Stevens RC, Goodman MF, Chen XS. Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications. Nature. 456: 121-4. PMID 18849968 DOI: 10.1038/Nature07357  0.81
2008 Fletcher RJ, Shen J, Holden LG, Chen XS. Identification of amino acids important for the biochemical activity of Methanothermobacter thermautotrophicus MCM. Biochemistry. 47: 9981-6. PMID 18754676 DOI: 10.1021/Bi800032T  0.787
2008 Thomas M, Dasgupta J, Zhang Y, Chen X, Banks L. Analysis of specificity determinants in the interactions of different HPV E6 proteins with their PDZ domain-containing substrates. Virology. 376: 371-8. PMID 18452965 DOI: 10.1016/J.Virol.2008.03.021  0.301
2008 Greenleaf WB, Shen J, Gai D, Chen XS. Systematic study of the functions for the residues around the nucleotide pocket in simian virus 40 AAA+ hexameric helicase. Journal of Virology. 82: 6017-23. PMID 18400864 DOI: 10.1128/JVI.00387-08  0.307
2008 Wang G, Klein MG, Tokonzaba E, Zhang Y, Holden LG, Chen XS. The structure of a DnaB-family replicative helicase and its interactions with primase. Nature Structural & Molecular Biology. 15: 94-100. PMID 18157148 DOI: 10.1038/Nsmb1356  0.806
2007 Chang YP, Wang G, Bermudez V, Hurwitz J, Chen XS. Crystal structure of the GINS complex and functional insights into its role in DNA replication. Proceedings of the National Academy of Sciences of the United States of America. 104: 12685-90. PMID 17652513 DOI: 10.1073/Pnas.0705558104  0.321
2007 Prochnow C, Bransteitter R, Klein MG, Goodman MF, Chen XS. The APOBEC-2 crystal structure and functional implications for the deaminase AID. Nature. 445: 447-51. PMID 17187054 DOI: 10.1038/Nature05492  0.801
2006 Lilyestrom W, Klein MG, Zhang R, Joachimiak A, Chen XS. Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor. Genes & Development. 20: 2373-82. PMID 16951253 DOI: 10.1101/gad.1456306  0.791
2006 Valle M, Chen XS, Donate LE, Fanning E, Carazo JM. Structural basis for the cooperative assembly of large T antigen on the origin of replication. Journal of Molecular Biology. 357: 1295-305. PMID 16481006 DOI: 10.1016/J.Jmb.2006.01.021  0.322
2006 Fletcher RJ, Chen XS. Biochemical activities of the BOB1 mutant in Methanobacterium thermoautotrophicum MCM. Biochemistry. 45: 462-7. PMID 16401076 DOI: 10.1021/bi051754z  0.355
2005 Fletcher RJ, Shen J, Gómez-Llorente Y, Martín CS, Carazo JM, Chen XS. Double hexamer disruption and biochemical activities of Methanobacterium thermoautotrophicum MCM. The Journal of Biological Chemistry. 280: 42405-10. PMID 16221679 DOI: 10.1074/Jbc.M509773200  0.339
2003 Li D, Zhao R, Lilyestrom W, Gai D, Zhang R, DeCaprio JA, Fanning E, Jochimiak A, Szakonyi G, Chen XS. Structure of the replicative helicase of the oncoprotein SV40 large tumour antigen. Nature. 423: 512-8. PMID 12774115 DOI: 10.1038/Nature01691  0.815
2003 Fletcher RJ, Bishop BE, Leon RP, Sclafani RA, Ogata CM, Chen XS. The structure and function of MCM from archaeal M. Thermoautotrophicum. Nature Structural Biology. 10: 160-7. PMID 12548282 DOI: 10.1038/Nsb893  0.329
2002 Hannan J, Young K, Szakonyi G, Overduin MJ, Perkins SJ, Chen X, Holers VM. Structure of complement receptor (CR) 2 and CR2-C3d complexes Biochemical Society Transactions. 30: 983-989. PMID 12440958 DOI: 10.1042/Bst0300983  0.315
1992 Chen X, Bruening G. Nucleotide sequence and genetic map of cowpea severe mosaic virus RNA 2 and comparisons with RNA 2 of other comoviruses Virology. 187: 682-692. PMID 1546463 DOI: 10.1016/0042-6822(92)90471-Z  0.622
1992 Chen X, Bruening G. Cloned DNA copies of cowpea severe mosaic virus genomic RNAs: Infectious transcripts and complete nucleotide sequence of RNA 1 Virology. 191: 607-618. PMID 1448917 DOI: 10.1016/0042-6822(92)90236-I  0.622
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