| Year |
Citation |
Score |
| 2022 |
Murphy R, Irnaten M, Hopkins A, O'Callaghan J, Stamer WD, Clark AF, Wallace D, O'Brien CJ. Matrix Mechanotransduction via Yes-Associated Protein in Human Lamina Cribrosa Cells in Glaucoma. Investigative Ophthalmology & Visual Science. 63: 16. PMID 35015027 DOI: 10.1167/iovs.63.1.16 |
0.303 |
|
| 2021 |
Sugali CK, Rayana NP, Dai J, Peng M, Harris SL, Webber HC, Liu S, Dixon SG, Parekh PH, Martin EA, Cantor LB, Fellman RL, Godfrey DG, Butler MR, Emanuel ME, ... ... Clark AF, et al. Full title: The canonical Wnt signaling pathway inhibits the glucocorticoid receptor signaling pathway in the trabecular meshwork. The American Journal of Pathology. PMID 33705750 DOI: 10.1016/j.ajpath.2021.02.018 |
0.351 |
|
| 2020 |
Irnaten M, Duff A, Clark A, O'Brien C. Intra-Cellular Calcium Signaling Pathways (PKC, RAS/RAF/MAPK, PI3K) in Lamina Cribrosa Cells in Glaucoma. Journal of Clinical Medicine. 10. PMID 33375386 DOI: 10.3390/jcm10010062 |
0.313 |
|
| 2018 |
Irnaten M, Zhdanov A, Brennan D, Crotty T, Clark A, Papkovsky D, O'Brien C. Activation of the NFAT-Calcium Signaling Pathway in Human Lamina Cribrosa Cells in Glaucoma. Investigative Ophthalmology & Visual Science. 59: 831-842. PMID 29411011 DOI: 10.1167/Iovs.17-22531 |
0.307 |
|
| 2017 |
Jain A, Zode G, Kasetti RB, Ran FA, Yan W, Sharma TP, Bugge K, Searby CC, Fingert JH, Zhang F, Clark AF, Sheffield VC. CRISPR-Cas9-based treatment of myocilin-associated glaucoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 28973933 DOI: 10.1073/Pnas.1706193114 |
0.51 |
|
| 2017 |
Webber HC, Bermudez JY, Sethi A, Clark AF, Mao W. RE: "Letter to the Editor concerning Webber et al. Exp Eye Res. 148:97-102, 2016". Experimental Eye Research. PMID 28478122 DOI: 10.1016/j.exer.2017.05.001 |
0.422 |
|
| 2017 |
Mody AA, Wordinger RJ, Clark AF. Role of ID Proteins in BMP4 Inhibition of Profibrotic Effects of TGF-β2 in Human TM Cells. Investigative Ophthalmology & Visual Science. 58: 849-859. PMID 28159972 DOI: 10.1167/iovs.16-20472 |
0.327 |
|
| 2016 |
Tovar-Vidales T, Fitzgerald AM, Clark AF. Human trabecular meshwork cells express BMP antagonist mRNAs and proteins. Experimental Eye Research. PMID 27167364 DOI: 10.1016/J.Exer.2016.05.004 |
0.343 |
|
| 2016 |
Webber HC, Bermudez JY, Sethi A, Clark AF, Mao W. Crosstalk between TGFβ and Wnt signaling pathways in the human trabecular meshwork. Experimental Eye Research. PMID 27091054 DOI: 10.1016/j.exer.2016.04.007 |
0.577 |
|
| 2015 |
McDowell CM, Hernandez H, Mao W, Clark AF. Gremlin Induces Ocular Hypertension in Mice Through Smad3-Dependent Signaling. Investigative Ophthalmology & Visual Science. 56: 5485-92. PMID 26284554 DOI: 10.1167/iovs.15-16993 |
0.334 |
|
| 2015 |
Sharma TP, Liu Y, Wordinger RJ, Pang IH, Clark AF. Neuritin 1 promotes retinal ganglion cell survival and axonal regeneration following optic nerve crush. Cell Death & Disease. 6: e1661. PMID 25719245 DOI: 10.1038/Cddis.2015.22 |
0.496 |
|
| 2014 |
Sharma TP, McDowell CM, Liu Y, Wagner AH, Thole D, Faga BP, Wordinger RJ, Braun TA, Clark AF. Optic nerve crush induces spatial and temporal gene expression patterns in retina and optic nerve of BALB/cJ mice. Molecular Neurodegeneration. 9: 14. PMID 24767545 DOI: 10.1186/1750-1326-9-14 |
0.489 |
|
| 2014 |
Wordinger RJ, Sharma T, Clark AF. The role of TGF-β2 and bone morphogenetic proteins in the trabecular meshwork and glaucoma. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 30: 154-62. PMID 24517218 DOI: 10.1089/Jop.2013.0220 |
0.543 |
|
| 2013 |
McDowell CM, Tebow HE, Wordinger RJ, Clark AF. Smad3 is necessary for transforming growth factor-beta2 induced ocular hypertension in mice. Experimental Eye Research. 116: 419-23. PMID 24184030 DOI: 10.1016/J.Exer.2013.10.017 |
0.339 |
|
| 2013 |
Medina-Ortiz WE, Belmares R, Neubauer S, Wordinger RJ, Clark AF. Cellular fibronectin expression in human trabecular meshwork and induction by transforming growth factor-β2. Investigative Ophthalmology & Visual Science. 54: 6779-88. PMID 24030464 DOI: 10.1167/iovs.13-12298 |
0.339 |
|
| 2013 |
Tovar-Vidales T, Fitzgerald AM, Clark AF, Wordinger RJ. Transforming growth factor-β2 induces expression of biologically active bone morphogenetic protein-1 in human trabecular meshwork cells. Investigative Ophthalmology & Visual Science. 54: 4741-8. PMID 23788373 DOI: 10.1167/Iovs.13-12203 |
0.359 |
|
| 2013 |
Sethi A, Wordinger RJ, Clark AF. Gremlin utilizes canonical and non-canonical TGFβ signaling to induce lysyl oxidase (LOX) genes in human trabecular meshwork cells. Experimental Eye Research. 113: 117-27. PMID 23748100 DOI: 10.1016/J.Exer.2013.05.011 |
0.613 |
|
| 2012 |
Fitzgerald AM, Benz C, Clark AF, Wordinger RJ. The effects of transforming growth factor-β2 on the expression of follistatin and activin A in normal and glaucomatous human trabecular meshwork cells and tissues. Investigative Ophthalmology & Visual Science. 53: 7358-69. PMID 23010638 DOI: 10.1167/Iovs.12-10292 |
0.316 |
|
| 2012 |
Mao W, Millar JC, Wang WH, Silverman SM, Liu Y, Wordinger RJ, Rubin JS, Pang IH, Clark AF. Existence of the canonical Wnt signaling pathway in the human trabecular meshwork. Investigative Ophthalmology & Visual Science. 53: 7043-51. PMID 22956608 DOI: 10.1167/Iovs.12-9664 |
0.334 |
|
| 2012 |
Sethi A, Wordinger RJ, Clark AF. Focus on molecules: lysyl oxidase. Experimental Eye Research. 104: 97-8. PMID 22381166 DOI: 10.1016/J.Exer.2012.02.002 |
0.528 |
|
| 2011 |
Bollinger KE, Crabb JS, Yuan X, Putliwala T, Clark AF, Crabb JW. Quantitative proteomics: TGFβ₂ signaling in trabecular meshwork cells. Investigative Ophthalmology & Visual Science. 52: 8287-94. PMID 21917933 DOI: 10.1167/iovs.11-8218 |
0.328 |
|
| 2011 |
Zode GS, Sethi A, Brun-Zinkernagel AM, Chang IF, Clark AF, Wordinger RJ. Transforming growth factor-β2 increases extracellular matrix proteins in optic nerve head cells via activation of the Smad signaling pathway. Molecular Vision. 17: 1745-58. PMID 21738403 |
0.594 |
|
| 2011 |
Tovar-Vidales T, Clark AF, Wordinger RJ. Transforming growth factor-beta2 utilizes the canonical Smad-signaling pathway to regulate tissue transglutaminase expression in human trabecular meshwork cells. Experimental Eye Research. 93: 442-51. PMID 21722634 DOI: 10.1016/J.Exer.2011.06.011 |
0.417 |
|
| 2011 |
Sethi A, Jain A, Zode GS, Wordinger RJ, Clark AF. Role of TGFbeta/Smad signaling in gremlin induction of human trabecular meshwork extracellular matrix proteins. Investigative Ophthalmology & Visual Science. 52: 5251-9. PMID 21642622 DOI: 10.1167/Iovs.11-7587 |
0.607 |
|
| 2011 |
Sethi A, Mao W, Wordinger RJ, Clark AF. Transforming growth factor-beta induces extracellular matrix protein cross-linking lysyl oxidase (LOX) genes in human trabecular meshwork cells. Investigative Ophthalmology & Visual Science. 52: 5240-50. PMID 21546528 DOI: 10.1167/Iovs.11-7287 |
0.608 |
|
| 2009 |
Kirwan RP, Wordinger RJ, Clark AF, O'Brien CJ. Differential global and extra-cellular matrix focused gene expression patterns between normal and glaucomatous human lamina cribrosa cells. Molecular Vision. 15: 76-88. PMID 19145252 |
0.331 |
|
| 2008 |
Wang WH, McNatt LG, Pang IH, Millar JC, Hellberg PE, Hellberg MH, Steely HT, Rubin JS, Fingert JH, Sheffield VC, Stone EM, Clark AF. Increased expression of the WNT antagonist sFRP-1 in glaucoma elevates intraocular pressure. The Journal of Clinical Investigation. 118: 1056-64. PMID 18274669 DOI: 10.1172/Jci33871 |
0.399 |
|
| 2008 |
Wang WH, McNatt LG, Pang IH, Hellberg PE, Fingert JH, McCartney MD, Clark AF. Increased expression of serum amyloid A in glaucoma and its effect on intraocular pressure. Investigative Ophthalmology & Visual Science. 49: 1916-23. PMID 18223246 DOI: 10.1167/Iovs.07-1104 |
0.309 |
|
| 2007 |
Zode GS, Clark AF, Wordinger RJ. Activation of the BMP canonical signaling pathway in human optic nerve head tissue and isolated optic nerve head astrocytes and lamina cribrosa cells. Investigative Ophthalmology & Visual Science. 48: 5058-67. PMID 17962458 DOI: 10.1167/Iovs.07-0127 |
0.321 |
|
| 2007 |
Wordinger RJ, Fleenor DL, Hellberg PE, Pang IH, Tovar TO, Zode GS, Fuller JA, Clark AF. Effects of TGF-beta2, BMP-4, and gremlin in the trabecular meshwork: implications for glaucoma. Investigative Ophthalmology & Visual Science. 48: 1191-200. PMID 17325163 DOI: 10.1167/Iovs.06-0296 |
0.367 |
|
| 2006 |
Fleenor DL, Shepard AR, Hellberg PE, Jacobson N, Pang IH, Clark AF. TGFbeta2-induced changes in human trabecular meshwork: implications for intraocular pressure. Investigative Ophthalmology & Visual Science. 47: 226-34. PMID 16384967 DOI: 10.1167/iovs.05-1060 |
0.326 |
|
| 2005 |
Kirwan RP, Fenerty CH, Crean J, Wordinger RJ, Clark AF, O'Brien CJ. Influence of cyclical mechanical strain on extracellular matrix gene expression in human lamina cribrosa cells in vitro. Molecular Vision. 11: 798-810. PMID 16205625 DOI: 10.1016/S0021-9290(06)84552-5 |
0.354 |
|
| 2005 |
Kirwan RP, Leonard MO, Murphy M, Clark AF, O'Brien CJ. Transforming growth factor-beta-regulated gene transcription and protein expression in human GFAP-negative lamina cribrosa cells. Glia. 52: 309-24. PMID 16078232 DOI: 10.1002/glia.20247 |
0.314 |
|
| 2002 |
Wordinger RJ, Agarwal R, Talati M, Fuller J, Lambert W, Clark AF. Expression of bone morphogenetic proteins (BMP), BMP receptors, and BMP associated proteins in human trabecular meshwork and optic nerve head cells and tissues. Molecular Vision. 8: 241-50. PMID 12131877 |
0.321 |
|
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