Year |
Citation |
Score |
2022 |
Parsons AJ, Ophir SI, Gardner TJ, Paredes JC, Stein KR, Kwasny SM, Cardinale SC, Torhan M, Prichard MN, James SH, Atanasoff KE, G-Dayanandan N, Bowlin TL, Opperman TJ, Tortorella D. Investigating N-arylpyrimidinamine (NAPA) compounds as early-stage inhibitors against human cytomegalovirus. Antiviral Research. 209: 105474. PMID 36511318 DOI: 10.1016/j.antiviral.2022.105474 |
0.315 |
|
2020 |
Toth K, Hussein ITM, Tollefson AE, Ying B, Spencer JF, Eagar J, James SH, Prichard MN, Wold WSM, Bowlin TL. Filociclovir is a potent and inhibitor of human adenoviruses. Antimicrobial Agents and Chemotherapy. PMID 32816736 DOI: 10.1128/Aac.01299-20 |
0.445 |
|
2020 |
Acosta E, Bowlin T, Brooks J, Chiang L, Hussein I, Kimberlin D, Kauvar LM, Leavitt R, Prichard M, Whitley R. Advances in the Development of Therapeutics for Cytomegalovirus Infections. The Journal of Infectious Diseases. 221: S32-S44. PMID 32134483 DOI: 10.1093/Infdis/Jiz493 |
0.353 |
|
2020 |
Abdurakhmanova ER, Brusnakov MY, Golovchenko OV, Pilyo SG, Velychko NV, Harden EA, Prichard MN, James SH, Zhirnov VV, Brovarets VS. Synthesis and in vitro anticytomegalovirus activity of 5-hydroxyalkylamino-1,3-oxazoles derivatives Medicinal Chemistry Research. 29: 1669-1675. DOI: 10.1007/S00044-020-02593-6 |
0.329 |
|
2019 |
Kornii Y, Chumachenko S, Shablykin O, Prichard MN, James SH, Hartline C, Zhirnov V, Brovarets V. New 2-Oxoimidazolidine Derivatives: Design, Synthesis and Evaluation of Anti-BK Virus Activities in Vitro. Chemistry & Biodiversity. PMID 31479201 DOI: 10.1002/Cbdv.201900391 |
0.339 |
|
2019 |
Kachaeva MV, Pilyo SG, Hartline CB, Harden EA, Prichard MN, Zhirnov VV, Brovarets VS. In vitro activity of novel derivatives of 1,3-oxazole-4-carboxylate and 1,3-oxazole-4-carbonitrile against human cytomegalovirus Medicinal Chemistry Research. 28: 1205-1211. DOI: 10.1007/S00044-019-02365-X |
0.367 |
|
2018 |
D'Aiuto L, McNulty J, Hartline C, Demers M, Kalkeri R, Wood J, McClain L, Chattopadhyay A, Zhi Y, Naciri J, Smith A, Yolken R, Chowdari K, Zepeda-Velazquez C, Dokuburra CB, ... ... Prichard M, et al. R430: A potent inhibitor of DNA and RNA viruses. Scientific Reports. 8: 16662. PMID 30413769 DOI: 10.1038/S41598-018-33904-Y |
0.439 |
|
2018 |
Keith KA, Hartline CB, Bowlin TL, Prichard MN. A standardized approach to the evaluation of antivirals against DNA viruses: Polyomaviruses and lymphotropic herpesviruses. Antiviral Research. 159: 122-129. PMID 30287227 DOI: 10.1016/J.Antiviral.2018.09.016 |
0.47 |
|
2018 |
Hartline CB, Keith KA, Eagar J, Harden EA, Bowlin TL, Prichard MN. A standardized approach to the evaluation of antivirals against DNA viruses: Orthopox-, adeno-, and herpesviruses. Antiviral Research. 159: 104-112. PMID 30287226 DOI: 10.1016/J.Antiviral.2018.09.015 |
0.472 |
|
2018 |
Britt WJ, Prichard MN. New therapies for human cytomegalovirus infections. Antiviral Research. PMID 30227153 DOI: 10.1016/J.Antiviral.2018.09.003 |
0.398 |
|
2018 |
Toth K, Spencer JF, Ying B, Tollefson AE, Hartline CB, Richard ET, Fan J, Lyu J, Kashemirov BA, Harteg C, Reyna D, Lipka E, Prichard MN, McKenna CE, Wold WSM. USC-087 protects Syrian hamsters against lethal challenge with human species C adenoviruses. Antiviral Research. PMID 29510156 DOI: 10.1016/J.Antiviral.2018.03.001 |
0.366 |
|
2017 |
Quenelle DC, Birkmann A, Goldner T, Pfaff T, Zimmermann H, Bonsmann S, Collins DJ, Rice TL, Prichard MN. Efficacy of pritelivir and acyclovir in the treatment of herpes simplex virus infections in a mouse model of herpes simplex encephalitis. Antiviral Research. PMID 29113740 DOI: 10.1016/J.Antiviral.2017.11.002 |
0.38 |
|
2017 |
Smee DF, Prichard MN. Comparison of three dimensional synergistic analyses of percentage versus logarithmic data in antiviral studies. Antiviral Research. 145: 1-5. PMID 28676302 DOI: 10.1016/J.Antiviral.2017.06.022 |
0.36 |
|
2017 |
Cassady KA, Bauer DF, Roth J, Chambers MR, Shoeb T, Coleman J, Prichard M, Gillespie GY, Markert JM. Pre-clinical Assessment of C134, a Chimeric Oncolytic Herpes Simplex Virus, in Mice and Non-human Primates. Molecular Therapy Oncolytics. 5: 1-10. PMID 28345027 DOI: 10.1016/J.Omto.2017.02.001 |
0.341 |
|
2016 |
Manos-Turvey A, Al-Ashtal HA, Needham PG, Hartline CB, Prichard MN, Wipf P, Brodsky JL. Dihydropyrimidinones and -thiones with improved activity against human polyomavirus family members. Bioorganic & Medicinal Chemistry Letters. PMID 27624078 DOI: 10.1016/J.Bmcl.2016.08.080 |
0.397 |
|
2016 |
Lanier ER, Foster S, Brundage T, Chou S, Prichard MN, Kleiboeker S, Wilson C, Colville D, Mommeja-Marin H. Analysis of Cytomegalovirus DNA Polymerase Gene Mutations in a Phase 2 Clinical Trial of Brincidofovir Prophylaxis. The Journal of Infectious Diseases. PMID 26941282 DOI: 10.1093/Infdis/Jiw073 |
0.313 |
|
2016 |
Pécheur EI, Borisevich V, Halfmann P, Morrey JD, Smee DF, Prichard M, Mire CE, Kawaoka Y, Geisbert TW, Polyak SJ. The Synthetic Antiviral Drug Arbidol Inhibits Globally Prevalent Pathogenic Viruses. Journal of Virology. PMID 26739045 DOI: 10.1128/Jvi.02077-15 |
0.461 |
|
2015 |
Komazin-Meredith G, Cardinale SC, Comeau K, Magalhaes KJ, Hartline CB, Williams JD, Opperman TJ, Prichard MN, Bowlin TL. TAOK3 phosphorylates the methylenecyclopropane nucleoside MBX 2168 to its monophosphate. Antiviral Research. 119: 23-7. PMID 25857706 DOI: 10.1016/J.Antiviral.2015.04.001 |
0.442 |
|
2015 |
James SH, Larson KB, Acosta EP, Prichard MN. Helicase-primase as a target of new therapies for herpes simplex virus infections. Clinical Pharmacology and Therapeutics. 97: 66-78. PMID 25670384 DOI: 10.1002/Cpt.3 |
0.393 |
|
2014 |
Fiallos E, Judkins J, Matlaf L, Prichard M, Dittmer D, Cobbs C, Soroceanu L. Human cytomegalovirus gene expression in long-term infected glioma stem cells. Plos One. 9. PMID 25549333 DOI: 10.1371/Journal.Pone.0116178 |
0.325 |
|
2014 |
Prichard MN, Whitley RJ. The development of new therapies for human herpesvirus 6. Current Opinion in Virology. 9: 148-53. PMID 25462447 DOI: 10.1016/J.Coviro.2014.09.019 |
0.376 |
|
2014 |
Tardif KD, Jorgensen S, Langer J, Prichard M, Schlaberg R. Simultaneous titration and phenotypic antiviral drug susceptibility testing for herpes simplex virus 1 and 2. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 61: 382-6. PMID 25204613 DOI: 10.1016/J.Jcv.2014.08.015 |
0.362 |
|
2014 |
James SH, Prichard MN. Current and future therapies for herpes simplex virus infections: mechanism of action and drug resistance. Current Opinion in Virology. 8: 54-61. PMID 25036916 DOI: 10.1016/J.Coviro.2014.06.003 |
0.393 |
|
2014 |
Webel R, Hakki M, Prichard MN, Rawlinson WD, Marschall M, Chou S. Differential properties of cytomegalovirus pUL97 kinase isoforms affect viral replication and maribavir susceptibility. Journal of Virology. 88: 4776-85. PMID 24522923 DOI: 10.1128/Jvi.00192-14 |
0.412 |
|
2014 |
Whitley RJ, Prichard M. A novel potential therapy for HSV. The New England Journal of Medicine. 370: 273-4. PMID 24428473 DOI: 10.1056/Nejme1313982 |
0.384 |
|
2014 |
Basu A, Antanasijevic A, Wang M, Li B, Mills DM, Ames JA, Nash PJ, Williams JD, Peet NP, Moir DT, Prichard MN, Keith KA, Barnard DL, Caffrey M, Rong L, et al. New small molecule entry inhibitors targeting hemagglutinin-mediated influenza a virus fusion. Journal of Virology. 88: 1447-60. PMID 24198411 DOI: 10.1128/Jvi.01225-13 |
0.419 |
|
2014 |
Komazin-Meredith G, Chou S, Prichard MN, Hartline CB, Cardinale SC, Comeau K, Williams JD, Khan AR, Peet NP, Bowlin TL. Human cytomegalovirus UL97 kinase is involved in the mechanism of action of methylenecyclopropane analogs with 6-ether and -thioether substitutions. Antimicrobial Agents and Chemotherapy. 58: 274-8. PMID 24145545 DOI: 10.1128/Aac.01726-13 |
0.456 |
|
2014 |
Kesel AJ, Huang Z, Murray MG, Prichard MN, Caboni L, Nevin DK, Fayne D, Lloyd DG, Detorio MA, Schinazi RF. Retinazone inhibits certain blood-borne human viruses including Ebola virus Zaire. Antiviral Chemistry & Chemotherapy. 23: 197-215. PMID 23636868 DOI: 10.3851/Imp2568 |
0.42 |
|
2014 |
Oliver S, Potter J, Covington R, Tipler K, Kimberlin DW, Prichard MN. 1143GenMark ESensor Respiratory Viral Panel in an Inpatient Pediatric Population Open Forum Infectious Diseases. 1: S339-S339. DOI: 10.1093/Ofid/Ofu052.851 |
0.332 |
|
2013 |
Komazin-Meredith G, Cardinale SC, Williams JD, Peet NP, Prichard MN, Bowlin TL. Human herpesvirus 6 U69 kinase phosphorylates the methylenecyclopropane nucleosides cyclopropavir, MBX 2168, and MBX 1616 to their monophosphates. Antimicrobial Agents and Chemotherapy. 57: 5760-2. PMID 23979753 DOI: 10.1128/Aac.00978-13 |
0.376 |
|
2013 |
Prichard MN, Williams JD, Komazin-Meredith G, Khan AR, Price NB, Jefferson GM, Harden EA, Hartline CB, Peet NP, Bowlin TL. Synthesis and antiviral activities of methylenecyclopropane analogs with 6-alkoxy and 6-alkylthio substitutions that exhibit broad-spectrum antiviral activity against human herpesviruses. Antimicrobial Agents and Chemotherapy. 57: 3518-27. PMID 23669381 DOI: 10.1128/Aac.00429-13 |
0.483 |
|
2013 |
James SH, Price NB, Hartline CB, Lanier ER, Prichard MN. Selection and recombinant phenotyping of a novel CMX001 and cidofovir resistance mutation in human cytomegalovirus. Antimicrobial Agents and Chemotherapy. 57: 3321-5. PMID 23650158 DOI: 10.1128/Aac.00062-13 |
0.383 |
|
2012 |
Williams JD, Khan AR, Harden EA, Hartline CB, Jefferson GM, Keith KA, Prichard MN, Zemlicka J, Peet NP, Bowlin TL. Synthesis and antiviral activity of certain second generation methylenecyclopropane nucleosides. Bioorganic & Medicinal Chemistry. 20: 3710-8. PMID 22607883 DOI: 10.1016/J.Bmc.2012.04.049 |
0.346 |
|
2012 |
Gill RB, James SH, Prichard MN. Human cytomegalovirus UL97 kinase alters the accumulation of CDK1. The Journal of General Virology. 93: 1743-55. PMID 22552942 DOI: 10.1099/Vir.0.039214-0 |
0.701 |
|
2012 |
Li C, Quenelle DC, Prichard MN, Drach JC, Zemlicka J. Synthesis and antiviral activity of 6-deoxycyclopropavir, a new prodrug of cyclopropavir. Bioorganic & Medicinal Chemistry. 20: 2669-74. PMID 22417649 DOI: 10.1016/J.Bmc.2012.02.031 |
0.459 |
|
2012 |
Prichard MN, Kern ER. Orthopoxvirus targets for the development of new antiviral agents. Antiviral Research. 94: 111-25. PMID 22406470 DOI: 10.1016/J.Antiviral.2012.02.012 |
0.368 |
|
2011 |
Price NB, Prichard MN. Progress in the development of new therapies for herpesvirus infections. Current Opinion in Virology. 1: 548-54. PMID 22162744 DOI: 10.1016/J.Coviro.2011.10.015 |
0.383 |
|
2011 |
Schormann N, Sommers CI, Prichard MN, Keith KA, Noah JW, Nuth M, Ricciardi RP, Chattopadhyay D. Identification of protein-protein interaction inhibitors targeting vaccinia virus processivity factor for development of antiviral agents. Antimicrobial Agents and Chemotherapy. 55: 5054-62. PMID 21844323 DOI: 10.1128/Aac.00278-11 |
0.354 |
|
2011 |
Prichard MN, Kern ER, Hartline CB, Lanier ER, Quenelle DC. CMX001 potentiates the efficacy of acyclovir in herpes simplex virus infections. Antimicrobial Agents and Chemotherapy. 55: 4728-34. PMID 21788472 DOI: 10.1016/J.Antiviral.2011.03.013 |
0.442 |
|
2011 |
James SH, Hartline CB, Harden EA, Driebe EM, Schupp JM, Engelthaler DM, Keim PS, Bowlin TL, Kern ER, Prichard MN. Cyclopropavir inhibits the normal function of the human cytomegalovirus UL97 kinase. Antimicrobial Agents and Chemotherapy. 55: 4682-91. PMID 21788463 DOI: 10.1016/J.Antiviral.2011.03.010 |
0.43 |
|
2011 |
Valiaeva N, Wyles DL, Schooley RT, Hwu JB, Beadle JR, Prichard MN, Hostetler KY. Synthesis and antiviral evaluation of 9-(S)-[3-alkoxy-2-(phosphonomethoxy)propyl]nucleoside alkoxyalkyl esters: inhibitors of hepatitis C virus and HIV-1 replication. Bioorganic & Medicinal Chemistry. 19: 4616-25. PMID 21719300 DOI: 10.1016/J.Bmc.2011.06.009 |
0.348 |
|
2011 |
Ruiz J, Beadle JR, Buller RM, Schreiwer J, Prichard MN, Keith KA, Lewis KC, Hostetler KY. Synthesis, metabolic stability and antiviral evaluation of various alkoxyalkyl esters of cidofovir and 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine. Bioorganic & Medicinal Chemistry. 19: 2950-8. PMID 21493074 DOI: 10.1016/J.Bmc.2011.03.034 |
0.388 |
|
2011 |
Prichard MN, Frederick SL, Daily S, Borysko KZ, Townsend LB, Drach JC, Kern ER. Benzimidazole analogs inhibit human herpesvirus 6. Antimicrobial Agents and Chemotherapy. 55: 2442-5. PMID 21300829 DOI: 10.1128/Aac.01523-10 |
0.346 |
|
2011 |
Prichard MN, Kern ER. The search for new therapies for human cytomegalovirus infections. Virus Research. 157: 212-21. PMID 21095209 DOI: 10.1016/J.Virusres.2010.11.004 |
0.413 |
|
2011 |
Tower C, Fu L, Gill R, Prichard M, Lesort M, Sztul E. Human cytomegalovirus UL97 kinase prevents the deposition of mutant protein aggregates in cellular models of Huntington's disease and ataxia. Neurobiology of Disease. 41: 11-22. PMID 20732421 DOI: 10.1016/J.Nbd.2010.08.013 |
0.659 |
|
2010 |
Prichard MN, Kern ER. Antiviral Activity of 4'-thioIDU and Thymidine Analogs against Orthopoxviruses. Viruses. 2: 1968-83. PMID 21994716 DOI: 10.3390/V2091968 |
0.394 |
|
2010 |
Nguyen JT, Hoopes JD, Le MH, Smee DF, Patick AK, Faix DJ, Blair PJ, de Jong MD, Prichard MN, Went GT. Triple combination of amantadine, ribavirin, and oseltamivir is highly active and synergistic against drug resistant influenza virus strains in vitro. Plos One. 5: e9332. PMID 20179772 DOI: 10.1371/Journal.Pone.0009332 |
0.394 |
|
2010 |
Quenelle D, Prichard M, Hartline C, Harden E, Collins D, Rice T, Lanier R, Kern E. Enhanced Efficacy Using Combinations of CMX001 with Acyclovir Against Herpes Simplex Virus Infections In Vitro and In Mice Antiviral Research. 86: A65. DOI: 10.1016/J.Antiviral.2010.02.464 |
0.405 |
|
2010 |
Keith K, Harden E, Gill R, Marquez V, Kern E, Prichard M. Efficacy of N-methanocarbathymidine Against Herpes Simplex Virus is Cell Cycle Dependent Antiviral Research. 86: A58. DOI: 10.1016/J.Antiviral.2010.02.445 |
0.686 |
|
2010 |
Hartline C, Dittmer D, Drach J, Chen F, Hendrickson RC, Lefkowitz E, Prichard M. Changes in Human Cytomegalovirus Transcriptional Patterns Induced by Antiviral Drugs Antiviral Research. 86: A56. DOI: 10.1016/J.Antiviral.2010.02.439 |
0.304 |
|
2010 |
Bantia S, Kellogg D, Parker C, Upshaw R, Ilyushina N, Prichard M, Babu Y. A Single Intramuscular Injection of Peramivir Demonstrates Anti-influenza Activity Against Recently Isolated Pandemic Flu Virus H1N1 (A/CA/04/2009) Antiviral Research. 86: A29-A30. DOI: 10.1016/J.Antiviral.2010.02.361 |
0.378 |
|
2009 |
Valiaeva N, Prichard MN, Buller RM, Beadle JR, Hartline CB, Keith KA, Schriewer J, Trahan J, Hostetler KY. Antiviral evaluation of octadecyloxyethyl esters of (S)-3-hydroxy-2-(phosphonomethoxy)propyl nucleosides against herpesviruses and orthopoxviruses. Antiviral Research. 84: 254-9. PMID 19800369 DOI: 10.1016/J.Antiviral.2009.09.012 |
0.404 |
|
2009 |
Prichard MN, Quenelle DC, Hartline CB, Harden EA, Jefferson G, Frederick SL, Daily SL, Whitley RJ, Tiwari KN, Maddry JA, Secrist JA, Kern ER. Inhibition of herpesvirus replication by 5-substituted 4'-thiopyrimidine nucleosides. Antimicrobial Agents and Chemotherapy. 53: 5251-8. PMID 19770274 DOI: 10.1128/Aac.00417-09 |
0.474 |
|
2009 |
Stern-Ginossar N, Saleh N, Goldberg MD, Prichard M, Wolf DG, Mandelboim O. Analysis of human cytomegalovirus-encoded microRNA activity during infection Journal of Virology. 83: 10684-10693. PMID 19656885 DOI: 10.1128/Jvi.01292-09 |
0.301 |
|
2009 |
Nguyen JT, Hoopes JD, Smee DF, Prichard MN, Driebe EM, Engelthaler DM, Le MH, Keim PS, Spence RP, Went GT. Triple combination of oseltamivir, amantadine, and ribavirin displays synergistic activity against multiple influenza virus strains in vitro. Antimicrobial Agents and Chemotherapy. 53: 4115-26. PMID 19620324 DOI: 10.1128/Aac.00476-09 |
0.403 |
|
2009 |
Harden EA, Falshaw R, Carnachan SM, Kern ER, Prichard MN. Virucidal activity of polysaccharide extracts from four algal species against herpes simplex virus. Antiviral Research. 83: 282-9. PMID 19576248 DOI: 10.1016/J.Antiviral.2009.06.007 |
0.437 |
|
2009 |
Prichard MN. Function of human cytomegalovirus UL97 kinase in viral infection and its inhibition by maribavir. Reviews in Medical Virology. 19: 215-29. PMID 19434630 DOI: 10.1002/Rmv.615 |
0.44 |
|
2009 |
Mhaske SB, Ksebati B, Prichard MN, Drach JC, Zemlicka J. Phosphonate analogues of cyclopropavir phosphates and their E-isomers. Synthesis and antiviral activity. Bioorganic & Medicinal Chemistry. 17: 3892-9. PMID 19410465 DOI: 10.1016/J.Bmc.2009.04.020 |
0.421 |
|
2009 |
Gill RB, Frederick SL, Hartline CB, Chou S, Prichard MN. Conserved retinoblastoma protein-binding motif in human cytomegalovirus UL97 kinase minimally impacts viral replication but affects susceptibility to maribavir. Virology Journal. 6: 9. PMID 19159461 DOI: 10.1186/1743-422X-6-9 |
0.717 |
|
2009 |
Kern ER, Prichard MN, Quenelle DC, Keith KA, Tiwari KN, Maddry JA, Secrist JA. Activities of certain 5-substituted 4'-thiopyrimidine nucleosides against orthopoxvirus infections. Antimicrobial Agents and Chemotherapy. 53: 572-9. PMID 19029322 DOI: 10.1128/Aac.01257-08 |
0.483 |
|
2009 |
Kern E, Prichard M, Quenelle D, Keith K, Tiwari K, Maddry J, Secrist J. Activity of Certain 5-Substituted-4′-Thio Pyrimindine Nucleosides against Orthopoxvirus Infections Antiviral Research. 82: A72. DOI: 10.1016/J.Antiviral.2009.02.178 |
0.35 |
|
2009 |
Prichard M, Quenelle D, Hartline C, Harden E, Jefferson G, Frederick S, Rice T, Collins D, Tiwari K, Maddry J, Whitley R, Secrist J, Kern E. Inhibition of Herpesvirus Replication With 5-Iodo-4′-Thio-2′-Deoxyuridine Antiviral Research. 82: A67. DOI: 10.1016/J.Antiviral.2009.02.164 |
0.356 |
|
2009 |
Valiaeva N, Trahan J, Keith KA, Hartline C, Prichard M, Beadle JR, Hostetler KY. Evaluation of Octadecyloxyethyl Esters of 3-Hydroxy-2-(phosphonomethoxy)propyl Nucleosides Against HCMV, HSV and Poxviruses Antiviral Research. 82: A52. DOI: 10.1016/J.Antiviral.2009.02.120 |
0.31 |
|
2009 |
Quenelle D, Prichard M, Harden E, Collins D, Rice T, Painter G, Robertson A, Kern E. Comparative Efficacy of Treatment with CMX001 Versus Acyclovir in BALB/c Mice Infected with Herpes Simplex Virus Antiviral Research. 82: A51-A52. DOI: 10.1016/J.Antiviral.2009.02.118 |
0.374 |
|
2009 |
Hartline C, Gill R, Frederick S, Chou S, Prichard M. Conserved Retinoblastoma Protein-binding Motifs in Human Cytomegalovirus UL97 Minimally Impact Viral Replication But can Affect Susceptibility to Maribavir Antiviral Research. 82: A48. DOI: 10.1016/J.Antiviral.2009.02.108 |
0.695 |
|
2009 |
Harden E, Keith K, Daily S, Tiwari K, Maddry J, Secrist J, Kern E, Prichard M. Mutation of the Thymidine Kinases Encoded by Herpes Simplex Virus or Vaccinia Virus can Confer Resistance to 5-Iodo-4′-thio-2′-deoxyuridine Antiviral Research. 82: A48. DOI: 10.1016/J.Antiviral.2009.02.107 |
0.435 |
|
2009 |
Gill R, Benveniste E, Prichard M. The Effect of Human Cytomegalovirus Proteins PUL97 and PUL27 on Host Interferon Responses Antiviral Research. 82: A47. DOI: 10.1016/J.Antiviral.2009.02.106 |
0.659 |
|
2009 |
Keith K, Sanders S, Tiwari K, Maddry J, Secrist J, Jordan R, Hruby D, Lanier R, Painter G, Kern E, Prichard M. Combinations of 5-Iodo-4′-thio-2′-deoxyuridine and ST-246 or CMX001 Synergistically Inhibit Orthopoxvirus Replication In Vitro Antiviral Research. 82: A33-A34. DOI: 10.1016/J.Antiviral.2009.02.063 |
0.364 |
|
2008 |
Prichard MN, Hartline CB, Harden EA, Daily SL, Beadle JR, Valiaeva N, Kern ER, Hostetler KY. Inhibition of herpesvirus replication by hexadecyloxypropyl esters of purine- and pyrimidine-based phosphonomethoxyethyl nucleoside phosphonates. Antimicrobial Agents and Chemotherapy. 52: 4326-30. PMID 18852272 DOI: 10.1128/Aac.00918-08 |
0.435 |
|
2008 |
Bryan CJ, Prichard MN, Daily S, Jefferson G, Hartline C, Cassady KA, Hilliard L, Shimamura M. Acyclovir-resistant chronic verrucous vaccine strain varicella in a patient with neuroblastoma. The Pediatric Infectious Disease Journal. 27: 946-8. PMID 18776818 DOI: 10.1097/Inf.0B013E318175D85C |
0.375 |
|
2008 |
Quenelle DC, Collins DJ, Rice TL, Prichard MN, Marciani DJ, Kern ER. Effect of an immune enhancer, GPI-0100, on vaccination with live attenuated herpes simplex virus (HSV) type 2 or glycoprotein D on genital HSV-2 infections of guinea pigs. Antiviral Research. 80: 223-4. PMID 18573279 DOI: 10.1016/J.Antiviral.2008.05.011 |
0.351 |
|
2008 |
Becker MN, Obraztsova M, Kern ER, Quenelle DC, Keith KA, Prichard MN, Luo M, Moyer RW. Isolation and characterization of cidofovir resistant vaccinia viruses. Virology Journal. 5: 58. PMID 18479513 DOI: 10.1186/1743-422X-5-58 |
0.378 |
|
2008 |
Prichard MN, Sztul E, Daily SL, Perry AL, Frederick SL, Gill RB, Hartline CB, Streblow DN, Varnum SM, Smith RD, Kern ER. Human cytomegalovirus UL97 kinase activity is required for the hyperphosphorylation of retinoblastoma protein and inhibits the formation of nuclear aggresomes. Journal of Virology. 82: 5054-67. PMID 18321963 DOI: 10.1128/Jvi.02174-07 |
0.71 |
|
2008 |
Prichard MN, Kern ER, Quenelle DC, Keith KA, Moyer RW, Turner PC. Vaccinia virus lacking the deoxyuridine triphosphatase gene (F2L) replicates well in vitro and in vivo, but is hypersensitive to the antiviral drug (N)-methanocarbathymidine. Virology Journal. 5: 39. PMID 18321387 DOI: 10.1186/1743-422X-5-39 |
0.42 |
|
2008 |
Keith KA, Quenelle DC, Sanders S, Conley RC, Kern ER, Prichard MN. Novel Inhibitors of Orthopoxvirus Replication Target Vaccinia Virus P37 Envelope Protein Antiviral Research. 78: A58-A59. DOI: 10.1016/J.Antiviral.2008.01.124 |
0.415 |
|
2008 |
Harden E, Hartline C, Falshaw R, Carnachan S, Kern E, Prichard M. Virucidal Activity of Extracts from Four Algae Species Against Herpes Simplex Virus Antiviral Research. 78: A57. DOI: 10.1016/J.Antiviral.2008.01.120 |
0.357 |
|
2008 |
Quenelle D, Prichard M, Keith K, Collins D, Rice T, Secrist J, Tiwari K, Maddry J, Kern E. In Vitro and In Vivo Efficacy of a Pyrimidine Nucleoside Analog Against Vaccinia and Cowpox Viruses Antiviral Research. 78: A31. DOI: 10.1016/J.Antiviral.2008.01.052 |
0.406 |
|
2008 |
Prichard M, Daily S, Perry A, Kern E. Maribavir Inhibits the Replication of Human Herpesvirus 6 and the Activity of the U69 Protein Kinase Antiviral Research. 78: A29. DOI: 10.1016/J.Antiviral.2008.01.048 |
0.417 |
|
2007 |
Quenelle DC, Prichard MN, Keith KA, Hruby DE, Jordan R, Painter GR, Robertson A, Kern ER. Synergistic efficacy of the combination of ST-246 with CMX001 against orthopoxviruses. Antimicrobial Agents and Chemotherapy. 51: 4118-24. PMID 17724153 DOI: 10.1128/Aac.00762-07 |
0.399 |
|
2007 |
Prichard MN, Daily SL, Jefferson GM, Perry AL, Kern ER. A rapid DNA hybridization assay for the evaluation of antiviral compounds against Epstein-Barr virus. Journal of Virological Methods. 144: 86-90. PMID 17540461 DOI: 10.1016/J.Antiviral.2007.01.138 |
0.42 |
|
2007 |
Prichard MN, Keith KA, Johnson MP, Harden EA, McBrayer A, Luo M, Qiu S, Chattopadhyay D, Fan X, Torrence PF, Kern ER. Selective phosphorylation of antiviral drugs by vaccinia virus thymidine kinase. Antimicrobial Agents and Chemotherapy. 51: 1795-803. PMID 17325220 DOI: 10.1016/J.Antiviral.2007.01.150 |
0.466 |
|
2007 |
Zhang X, Amer A, Fan X, Balzarini J, Neyts J, De Clercq E, Prichard M, Kern E, Torrence PF. Synthesis and antiviral activities of new acyclic and "double-headed" nucleoside analogues. Bioorganic Chemistry. 35: 221-32. PMID 17270235 DOI: 10.1016/J.Bioorg.2006.11.003 |
0.455 |
|
2007 |
Choo H, Beadle JR, Kern ER, Prichard MN, Keith KA, Hartline CB, Trahan J, Aldern KA, Korba BE, Hostetler KY. Antiviral activities of novel 5-phosphono-pent-2-en-1-yl nucleosides and their alkoxyalkyl phosphonoesters. Antimicrobial Agents and Chemotherapy. 51: 611-5. PMID 17130297 DOI: 10.1128/Aac.00444-06 |
0.467 |
|
2007 |
KEITH K, KERN E, SANDERS S, CONLEY R, JORDAN R, HRUBY D, PAINTER G, PRICHARD M. Combinations of CMX-001 and ST-246 Synergistically Inhibit Orthopoxvirus Replication In Vitro Antiviral Research. 74: A79-A80. DOI: 10.1016/J.Antiviral.2007.01.135 |
0.367 |
|
2007 |
QUENELLE D, PRICHARD M, KEITH K, COLLINS D, JORDAN R, HRUBY D, PAINTER G, ROBERTSON A, KERN E. Efficacy of Delayed Therapy Using Combinations of ST-246 with CMX-001 Against Systemic Cowpox Virus Infections in Mice Antiviral Research. 74: A70-A70. DOI: 10.1016/J.Antiviral.2007.01.113 |
0.366 |
|
2007 |
QUENELLE D, PRICHARD M, DAILY S, COLLINS D, RICE T, PAINTER G, ROBERTSON A, KERN E. Efficacy of Oral CMX-001 Therapy Against Human Herpes Virus-6 Infections in SCID-hu Mice Antiviral Research. 74: A70-A70. DOI: 10.1016/J.Antiviral.2007.01.112 |
0.405 |
|
2007 |
PRICHARD M, DAILY S, PERRY A, HARTLINE C, KERN E. Inhibition of an Innate Antiviral Response by Human Cytomegalovirus UL97 Kinase is Antagonized by Maribavir Antiviral Research. 74: A41-A42. DOI: 10.1016/J.Antiviral.2007.01.043 |
0.38 |
|
2007 |
PRICHARD M, KEITH K, JOHNSON M, SCHORMANN N, SAMAL A, CHATTOPADHYAY D, KERN E. Structural Basis for the Expanded Substrate Specificity of Vaccinia Virus Thymidine Kinase: Insight from the Crystal Structure Antiviral Research. 74: A41-A41. DOI: 10.1016/J.Antiviral.2007.01.042 |
0.335 |
|
2006 |
Fan X, Zhang X, Zhou L, Keith KA, Prichard MN, Kern ER, Torrence PF. Toward orthopoxvirus countermeasures: a novel heteromorphic nucleoside of unusual structure. Journal of Medicinal Chemistry. 49: 4052-4. PMID 16821766 DOI: 10.1021/Jm060404N |
0.409 |
|
2006 |
Prichard MN, Quenelle DC, Bidanset DJ, Komazin G, Chou S, Drach JC, Kern ER. Human cytomegalovirus UL27 is not required for viral replication in human tissue implanted in SCID mice. Virology Journal. 3: 18. PMID 16571131 DOI: 10.1186/1743-422X-3-18 |
0.439 |
|
2006 |
Prichard MN, Keith KA, Quenelle DC, Kern ER. Activity and mechanism of action of N-methanocarbathymidine against herpesvirus and orthopoxvirus infections. Antimicrobial Agents and Chemotherapy. 50: 1336-41. PMID 16569849 DOI: 10.1128/Aac.50.4.1336-1341.2006 |
0.482 |
|
2006 |
Prichard MN, Williams AD, Keith KA, Harden EA, Kern ER. Distinct thymidine kinases encoded by cowpox virus and herpes simplex virus contribute significantly to the differential antiviral activity of nucleoside analogs. Antiviral Research. 71: 1-6. PMID 16530858 DOI: 10.1016/J.Antiviral.2006.01.013 |
0.446 |
|
2006 |
Arumugham B, Kim HJ, Prichard MN, Kern ER, Chu CK. Synthesis and antiviral activity of 7-deazaneplanocin A against orthopoxviruses (vaccinia and cowpox virus). Bioorganic & Medicinal Chemistry Letters. 16: 285-7. PMID 16275078 DOI: 10.1016/J.Bmcl.2005.10.007 |
0.413 |
|
2005 |
Prichard MN, Britt WJ, Daily SL, Hartline CB, Kern ER. Human cytomegalovirus UL97 Kinase is required for the normal intranuclear distribution of pp65 and virion morphogenesis. Journal of Virology. 79: 15494-502. PMID 16306620 DOI: 10.1128/Jvi.79.24.15494-15502.2005 |
0.437 |
|
2005 |
Williams-Aziz SL, Hartline CB, Harden EA, Daily SL, Prichard MN, Kushner NL, Beadle JR, Wan WB, Hostetler KY, Kern ER. Comparative activities of lipid esters of cidofovir and cyclic cidofovir against replication of herpesviruses in vitro. Antimicrobial Agents and Chemotherapy. 49: 3724-33. PMID 16127046 DOI: 10.1128/Aac.49.9.3724-3733.2005 |
0.459 |
|
2005 |
Prichard MN, Lawlor H, Duke GM, Mo C, Wang Z, Dixon M, Kemble G, Kern ER. Human cytomegalovirus uracil DNA glycosylase associates with ppUL44 and accelerates the accumulation of viral DNA. Virology Journal. 2: 55. PMID 16022730 DOI: 10.1186/1743-422X-2-55 |
0.343 |
|
2005 |
Prichard MN, Kaiwar R, Jackman WT, Quenelle DC, Collins DJ, Kern ER, Kemble GM, Spaete RR. Evaluation of AD472, a live attenuated recombinant herpes simplex virus type 2 vaccine in guinea pigs. Vaccine. 23: 5424-31. PMID 15950327 DOI: 10.1016/J.Vaccine.2005.02.028 |
0.401 |
|
2005 |
Kriesel JD, Spruance SL, Prichard M, Parker JN, Kern ER. Recurrent antiviral-resistant genital herpes in an immunocompetent patient. The Journal of Infectious Diseases. 192: 156-61. PMID 15942905 DOI: 10.1086/430612 |
0.363 |
|
2005 |
Prichard MN, Kern ER. Orthopoxvirus targets for the development of antiviral therapies. Current Drug Targets. Infectious Disorders. 5: 17-28. PMID 15777195 DOI: 10.2174/1568005053174627 |
0.435 |
|
2005 |
Kern ER, Kushner NL, Hartline CB, Williams-Aziz SL, Harden EA, Zhou S, Zemlicka J, Prichard MN. In vitro activity and mechanism of action of methylenecyclopropane analogs of nucleosides against herpesvirus replication. Antimicrobial Agents and Chemotherapy. 49: 1039-45. PMID 15728900 DOI: 10.1128/Aac.49.3.1039-1045.2005 |
0.43 |
|
2005 |
Mahmood K, Prichard MN, Duke GM, Kemble GW, Spaete RR. Human cytomegalovirus plasmid-based amplicon vector system for gene therapy. Genetic Vaccines and Therapy. 3: 1. PMID 15673469 DOI: 10.1186/1479-0556-3-1 |
0.427 |
|
2001 |
Tan Courcelle C, Courcelle J, Prichard MN, Mocarski ES. Requirement for uracil-DNA glycosylase during the transition to late-phase cytomegalovirus DNA replication Journal of Virology. 75: 7592-7601. PMID 11462031 DOI: 10.1128/Jvi.75.16.7592-7601.2001 |
0.393 |
|
2001 |
Wolf DG, Courcelle CT, Prichard MN, Mocarski ES. Distinct and separate roles for herpesvirus-conserved UL97 kinase in cytomegalovirus DNA synthesis and encapsidation Proceedings of the National Academy of Sciences of the United States of America. 98: 1895-1900. PMID 11172047 DOI: 10.1073/Pnas.98.4.1895 |
0.448 |
|
1999 |
Prichard MN, Gao N, Jairath S, Mulamba G, Krosky P, Coen DM, Parker BO, Pari GS. A recombinant human cytomegalovirus with a large deletion in UL97 has a severe replication deficiency Journal of Virology. 73: 5663-5670. PMID 10364316 DOI: 10.1128/Jvi.73.7.5663-5670.1999 |
0.457 |
|
1998 |
Prichard MN, Jairath S, Penfold MET, St. Jeor S, Bohlman MC, Pari GS. Identification of persistent RNA-DNA hybrid structures within the origin of replication of human cytomegalovirus Journal of Virology. 72: 6997-7004. PMID 9696791 DOI: 10.1128/Jvi.72.9.6997-7004.1998 |
0.346 |
|
1996 |
Prichard MN, Duke GM, Mocarski ES. Human cytomegalovirus uracil DNA glycosylase is required for the normal temporal regulation of both DNA synthesis and viral replication Journal of Virology. 70: 3018-3025. PMID 8627778 DOI: 10.1128/Jvi.70.5.3018-3025.1996 |
0.39 |
|
1995 |
Allen LB, Quenelle DC, Westbrook L, Taylor BA, Prichard MN, Brazier AD, Hollingshead MG, Shannon WM. In vitro and in vivo enhancement of ddI activity against Rauscher murine leukemia virus by ribavirin. Antiviral Research. 27: 317-23. PMID 8540752 DOI: 10.1016/0166-3542(95)00018-H |
0.409 |
|
1995 |
Prichard MN, Shipman C. Ribonucleotide reductase: An important enzyme in the replication of herpes simplex virus type 1 and a target for antiviral chemotherapy Chemotherapy. 41: 384-395. PMID 8521741 DOI: 10.1159/000239371 |
0.47 |
|
1995 |
Bilello JA, Bilello PA, Prichard M, Robins T, Drusano GL. Reduction of the in vitro activity of a77003, an inhibitor of human immunodeficiency virus protease, by human serum α1acid glycoprotein Journal of Infectious Diseases. 171: 546-551. PMID 7876599 DOI: 10.1093/Infdis/171.3.546 |
0.392 |
|
1993 |
Prichard MN, Prichard LE, Shipman C. Inhibitors of thymidylate synthase and dihydrofolate reductase potentiate the antiviral effect of acyclovir Antiviral Research. 20: 249-259. PMID 8385896 DOI: 10.1016/0166-3542(93)90024-D |
0.454 |
|
1993 |
Prichard MN, Prichard LE, Shipman C. Strategic design and three-dimensional analysis of antiviral drug combinations Antimicrobial Agents and Chemotherapy. 37: 540-545. PMID 8384816 DOI: 10.1128/Aac.37.3.540 |
0.33 |
|
1990 |
Prichard MN, Turk SR, Coleman LA, Engelhardt SL, Shipman C, Drach JC. A microtiter virus yield reduction assay for the evaluation of antiviral compounds against human cytomegalovirus and herpes simplex virus Journal of Virological Methods. 28: 101-106. PMID 2161417 DOI: 10.1016/0166-0934(90)90091-S |
0.44 |
|
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