Philip T. Liu, Ph.D. - Publications

Affiliations: 
2005 University of California, Los Angeles, Los Angeles, CA 
Area:
Molecular Biology, Immunology, Pathology

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Gottlieb C, Henrich M, Liu PT, Yacoubian V, Wang J, Chun R, Adams JS. gh-hroughput AMP ssay (HiTCA): A Novel Tool for Evaluating the Vitamin D-Dependent Antimicrobial Response. Nutrients. 15. PMID 36986109 DOI: 10.3390/nu15061380  0.426
2021 Gabitzsch E, Safrit JT, Verma M, Rice A, Sieling P, Zakin L, Shin A, Morimoto B, Adisetiyo H, Wong R, Bezawada A, Dinkins K, Balint J, Peykov V, Garban H, Liu P, et al. Dual-Antigen COVID-19 Vaccine Subcutaneous Prime Delivery With Oral Boosts Protects NHP Against SARS-CoV-2 Challenge. Frontiers in Immunology. 12: 729837. PMID 34603305 DOI: 10.3389/fimmu.2021.729837  0.524
2019 Kim EW, De Leon A, Jiang Z, Radu RA, Martineau AR, Chan ED, Bai X, Su WL, Montoya DJ, Modlin RL, Liu PT. Vitamin A Metabolism by Dendritic Cells Triggers an Antimicrobial Response against Mycobacterium tuberculosis. Msphere. 4. PMID 31167948 DOI: 10.1128/mSphere.00327-19  0.776
2019 Dang AT, Teles RM, Liu PT, Choi A, Legaspi A, Sarno EN, Ochoa MT, Parvatiyar K, Cheng G, Gilliet M, Bloom BR, Modlin RL. Autophagy links antimicrobial activity with antigen presentation in Langerhans cells. Jci Insight. 4. PMID 30996142 DOI: 10.1172/Jci.Insight.126955  0.597
2018 Zavala K, Gottlieb CA, Teles RM, Adams JS, Hewison M, Modlin RL, Liu PT. Intrinsic activation of the vitamin D antimicrobial pathway by M. leprae infection is inhibited by type I IFN. Plos Neglected Tropical Diseases. 12: e0006815. PMID 30300363 DOI: 10.1371/Journal.Pntd.0006815  0.68
2018 Kim EW, Teles RMB, Haile S, Liu PT, Modlin RL. Vitamin D status contributes to the antimicrobial activity of macrophages against Mycobacterium leprae. Plos Neglected Tropical Diseases. 12: e0006608. PMID 29965969 DOI: 10.1371/Journal.Pntd.0006608  0.676
2017 Park AJ, Agak GW, Qin M, Hisaw LD, Pirouz A, Kao S, Marinelli LJ, Garbán HJ, Thiboutot D, Liu PT, Kim J. G2A Attenuates Propionibacterium acnes Induction of Inflammatory Cytokines in Human Monocytes. Annals of Dermatology. 29: 688-698. PMID 29200756 DOI: 10.5021/Ad.2017.29.6.688  0.563
2016 Realegeno S, Kelly-Scumpia KM, Dang AT, Lu J, Teles R, Liu PT, Schenk M, Lee EY, Schmidt NW, Wong GC, Sarno EN, Rea TH, Ochoa MT, Pellegrini M, Modlin RL. S100A12 Is Part of the Antimicrobial Network against Mycobacterium leprae in Human Macrophages. Plos Pathogens. 12: e1005705. PMID 27355424 DOI: 10.1371/Journal.Ppat.1005705  0.626
2014 Montoya D, Inkeles MS, Liu PT, Realegeno S, Teles RM, Vaidya P, Munoz MA, Schenk M, Swindell WR, Chun R, Zavala K, Hewison M, Adams JS, Horvath S, Pellegrini M, et al. IL-32 is a molecular marker of a host defense network in human tuberculosis. Science Translational Medicine. 6: 250ra114. PMID 25143364 DOI: 10.1126/Scitranslmed.3009546  0.768
2014 Mehta MD, Liu PT. microRNAs in mycobacterial disease: friend or foe? Frontiers in Genetics. 5: 231. PMID 25076967 DOI: 10.3389/Fgene.2014.00231  0.396
2014 Chun RF, Liu PT, Modlin RL, Adams JS, Hewison M. Impact of vitamin D on immune function: lessons learned from genome-wide analysis. Frontiers in Physiology. 5: 151. PMID 24795646 DOI: 10.3389/Fphys.2014.00151  0.657
2014 Wheelwright M, Kim EW, Inkeles MS, De Leon A, Pellegrini M, Krutzik SR, Liu PT. All-trans retinoic acid-triggered antimicrobial activity against Mycobacterium tuberculosis is dependent on NPC2. Journal of Immunology (Baltimore, Md. : 1950). 192: 2280-90. PMID 24501203 DOI: 10.4049/Jimmunol.1301686  0.769
2014 Adams JS, Rafison B, Witzel S, Reyes RE, Shieh A, Chun R, Zavala K, Hewison M, Liu PT. Regulation of the extrarenal CYP27B1-hydroxylase. The Journal of Steroid Biochemistry and Molecular Biology. 144: 22-7. PMID 24388948 DOI: 10.1016/J.Jsbmb.2013.12.009  0.507
2014 Schenk M, Fabri M, Krutzik SR, Lee DJ, Vu DM, Sieling PA, Montoya D, Liu PT, Modlin RL. Interleukin-1β triggers the differentiation of macrophages with enhanced capacity to present mycobacterial antigen to T cells. Immunology. 141: 174-80. PMID 24032597 DOI: 10.1111/Imm.12167  0.783
2013 Adams JS, Ramin J, Rafison B, Windon C, Windon A, Liu PT. Redefining Human Vitamin D Sufficiency: Back to the Basics. Bone Research. 1: 2-10. PMID 25285234 DOI: 10.4248/Br201301002  0.41
2013 Klug-Micu GM, Stenger S, Sommer A, Liu PT, Krutzik SR, Modlin RL, Fabri M. CD40 ligand and interferon-γ induce an antimicrobial response against Mycobacterium tuberculosis in human monocytes. Immunology. 139: 121-8. PMID 23289765 DOI: 10.1111/Imm.12062  0.804
2013 Friedman AJ, Phan J, Schairer DO, Champer J, Qin M, Pirouz A, Blecher-Paz K, Oren A, Liu PT, Modlin RL, Kim J. Antimicrobial and anti-inflammatory activity of chitosan-alginate nanoparticles: a targeted therapy for cutaneous pathogens. The Journal of Investigative Dermatology. 133: 1231-9. PMID 23190896 DOI: 10.1038/Jid.2012.399  0.599
2012 Liu PT, Wheelwright M, Teles R, Komisopoulou E, Edfeldt K, Ferguson B, Mehta MD, Vazirnia A, Rea TH, Sarno EN, Graeber TG, Modlin RL. MicroRNA-21 targets the vitamin D-dependent antimicrobial pathway in leprosy. Nature Medicine. 18: 267-73. PMID 22286305 DOI: 10.1038/Nm.2584  0.602
2011 Fabri M, Stenger S, Shin DM, Yuk JM, Liu PT, Realegeno S, Lee HM, Krutzik SR, Schenk M, Sieling PA, Teles R, Montoya D, Iyer SS, Bruns H, Lewinsohn DM, et al. Vitamin D is required for IFN-gamma-mediated antimicrobial activity of human macrophages. Science Translational Medicine. 3: 104ra102. PMID 21998409 DOI: 10.1126/Scitranslmed.3003045  0.816
2011 Walker VP, Zhang X, Rastegar I, Liu PT, Hollis BW, Adams JS, Modlin RL. Cord blood vitamin D status impacts innate immune responses. The Journal of Clinical Endocrinology and Metabolism. 96: 1835-43. PMID 21470993 DOI: 10.1210/Jc.2010-1559  0.633
2011 Liu PT. The role of vitamin D in innate immunity: Antimicrobial activity, oxidative stress and barrier function Vitamin D. 1811-1823. DOI: 10.1016/B978-0-12-381978-9.10093-9  0.448
2010 Edfeldt K, Liu PT, Chun R, Fabri M, Schenk M, Wheelwright M, Keegan C, Krutzik SR, Adams JS, Hewison M, Modlin RL. T-cell cytokines differentially control human monocyte antimicrobial responses by regulating vitamin D metabolism. Proceedings of the National Academy of Sciences of the United States of America. 107: 22593-8. PMID 21149724 DOI: 10.1073/Pnas.1011624108  0.803
2010 Fiala M, Chattopadhay M, La Cava A, Tse E, Liu G, Lourenco E, Eskin A, Liu PT, Magpantay L, Tse S, Mahanian M, Weitzman R, Tong J, Nguyen C, Cho T, et al. IL-17A is increased in the serum and in spinal cord CD8 and mast cells of ALS patients. Journal of Neuroinflammation. 7: 76. PMID 21062492 DOI: 10.1186/1742-2094-7-76  0.318
2009 Liu PT, Schenk M, Walker VP, Dempsey PW, Kanchanapoomi M, Wheelwright M, Vazirnia A, Zhang X, Steinmeyer A, Zügel U, Hollis BW, Cheng G, Modlin RL. Convergence of IL-1beta and VDR activation pathways in human TLR2/1-induced antimicrobial responses. Plos One. 4: e5810. PMID 19503839 DOI: 10.1371/Journal.Pone.0005810  0.651
2009 Masoumi A, Goldenson B, Ghirmai S, Avagyan H, Zaghi J, Abel K, Zheng X, Espinosa-Jeffrey A, Mahanian M, Liu PT, Hewison M, Mizwickie M, Cashman J, Fiala M. 1alpha,25-dihydroxyvitamin D3 interacts with curcuminoids to stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients. Journal of Alzheimer's Disease : Jad. 17: 703-17. PMID 19433889 DOI: 10.3233/Jad-2009-1080  0.452
2009 Avagyan H, Goldenson B, Tse E, Masoumi A, Porter V, Wiedau-Pazos M, Sayre J, Ong R, Mahanian M, Koo P, Bae S, Micic M, Liu PT, Rosenthal MJ, Fiala M. Immune blood biomarkers of Alzheimer disease patients. Journal of Neuroimmunology. 210: 67-72. PMID 19329192 DOI: 10.1016/J.Jneuroim.2009.02.015  0.327
2009 Adams JS, Ren S, Liu PT, Chun RF, Lagishetty V, Gombart AF, Borregaard N, Modlin RL, Hewison M. Vitamin d-directed rheostatic regulation of monocyte antibacterial responses. Journal of Immunology (Baltimore, Md. : 1950). 182: 4289-95. PMID 19299728 DOI: 10.4049/Jimmunol.0803736  0.652
2009 Liu P, Hewison M, Adams JS. Vitamin D and innate immunity Clinical Reviews in Bone and Mineral Metabolism. 7: 176-184. DOI: 10.1007/S12018-009-9034-X  0.518
2008 Krutzik SR, Hewison M, Liu PT, Robles JA, Stenger S, Adams JS, Modlin RL. IL-15 links TLR2/1-induced macrophage differentiation to the vitamin D-dependent antimicrobial pathway. Journal of Immunology (Baltimore, Md. : 1950). 181: 7115-20. PMID 18981132 DOI: 10.4049/Jimmunol.181.10.7115  0.787
2008 Liu PT, Modlin RL. Human macrophage host defense against Mycobacterium tuberculosis. Current Opinion in Immunology. 20: 371-6. PMID 18602003 DOI: 10.1016/J.Coi.2008.05.014  0.622
2008 Jalian HR, Liu PT, Kanchanapoomi M, Phan JN, Legaspi AJ, Kim J. All-trans retinoic acid shifts Propionibacterium acnes-induced matrix degradation expression profile toward matrix preservation in human monocytes. The Journal of Investigative Dermatology. 128: 2777-82. PMID 18563181 DOI: 10.1038/Jid.2008.155  0.472
2008 Liu PT, Phan J, Tang D, Kanchanapoomi M, Hall B, Krutzik SR, Kim J. CD209(+) macrophages mediate host defense against Propionibacterium acnes. Journal of Immunology (Baltimore, Md. : 1950). 180: 4919-23. PMID 18354216 DOI: 10.4049/Jimmunol.180.7.4919  0.748
2008 Stenger S, Liu P, Modlin R, Ficker J, Wagner M. Vitamin D eliminiert Mycobacterium tuberculosis in humanen Alveolarmakrophagen durch die Hochregulation von Cathelicidin Pneumologie. 62. DOI: 10.1055/s-2008-1074416  0.334
2007 Adams JS, Chen H, Chun R, Ren S, Wu S, Gacad M, Nguyen L, Ride J, Liu P, Modlin R, Hewison M. Substrate and enzyme trafficking as a means of regulating 1,25-dihydroxyvitamin D synthesis and action: The human innate immune response Journal of Bone and Mineral Research. 22: V20-V24. PMID 18290716 DOI: 10.1359/Jbmr.07S214  0.621
2007 Liu PT, Stenger S, Tang DH, Modlin RL. Cutting edge: vitamin D-mediated human antimicrobial activity against Mycobacterium tuberculosis is dependent on the induction of cathelicidin. Journal of Immunology (Baltimore, Md. : 1950). 179: 2060-3. PMID 17675463 DOI: 10.4049/Jimmunol.179.4.2060  0.666
2007 Adams JS, Liu PT, Chun R, Modlin RL, Hewison M. Vitamin D in defense of the human immune response. Annals of the New York Academy of Sciences. 1117: 94-105. PMID 17656563 DOI: 10.1196/Annals.1402.036  0.653
2007 Fiala M, Liu PT, Espinosa-Jeffrey A, Rosenthal MJ, Bernard G, Ringman JM, Sayre J, Zhang L, Zaghi J, Dejbakhsh S, Chiang B, Hui J, Mahanian M, Baghaee A, Hong P, et al. Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcumin. Proceedings of the National Academy of Sciences of the United States of America. 104: 12849-54. PMID 17652175 DOI: 10.1073/Pnas.0701267104  0.335
2007 Hewison M, Burke F, Evans KN, Lammas DA, Sansom DM, Liu P, Modlin RL, Adams JS. Extra-renal 25-hydroxyvitamin D3-1alpha-hydroxylase in human health and disease. The Journal of Steroid Biochemistry and Molecular Biology. 103: 316-21. PMID 17368179 DOI: 10.1016/J.Jsbmb.2006.12.078  0.572
2007 Schauber J, Dorschner RA, Coda AB, Büchau AS, Liu PT, Kiken D, Helfrich YR, Kang S, Elalieh HZ, Steinmeyer A, Zügel U, Bikle DD, Modlin RL, Gallo RL. Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism. The Journal of Clinical Investigation. 117: 803-11. PMID 17290304 DOI: 10.1172/Jci30142  0.657
2007 Liu PT, Krutzik SR, Modlin RL. Therapeutic implications of the TLR and VDR partnership. Trends in Molecular Medicine. 13: 117-24. PMID 17276732 DOI: 10.1016/J.Molmed.2007.01.006  0.781
2006 Renn CN, Sanchez DJ, Ochoa MT, Legaspi AJ, Oh CK, Liu PT, Krutzik SR, Sieling PA, Cheng G, Modlin RL. TLR activation of Langerhans cell-like dendritic cells triggers an antiviral immune response. Journal of Immunology (Baltimore, Md. : 1950). 177: 298-305. PMID 16785525 DOI: 10.4049/Jimmunol.177.1.298  0.768
2006 Liu PT, Stenger S, Li H, Wenzel L, Tan BH, Krutzik SR, Ochoa MT, Schauber J, Wu K, Meinken C, Kamen DL, Wagner M, Bals R, Steinmeyer A, Zügel U, et al. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science (New York, N.Y.). 311: 1770-3. PMID 16497887 DOI: 10.1126/Science.1123933  0.827
2006 Liu P, Stenger S, Li H, Wenzel L, Tan B, Krutzik S, Ochoa M, Schauber J, Wu K, Meinken C, Kamen D, Wagner M, Bals R, Steinmeyer A, Zugel U, et al. Vitamin D3–Triggered Antimicrobial Response—Another Pleiotropic Effect beyond Mineral and Bone Metabolism Journal of the American Society of Nephrology. 17: 2949-2953. DOI: 10.1681/Asn.2006091030  0.739
2006 Stenger S, Liu P, Meinken C, Ganz T, Bals R, Zügel U, Steinmeyer A, Ficker J, Modlin R, Röllinghoff M, Wagner M. Toll-like Rezeptoren induzieren einen Vitamin D abhängigen Abwehrmechanismus gegen Mycobacterium tuberculosis in Alveolarmakrophagen Pneumologie. 60. DOI: 10.1055/s-2006-933856  0.371
2005 Krutzik SR, Tan B, Li H, Ochoa MT, Liu PT, Sharfstein SE, Graeber TG, Sieling PA, Liu YJ, Rea TH, Bloom BR, Modlin RL. TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells. Nature Medicine. 11: 653-60. PMID 15880118 DOI: 10.1038/Nm1246  0.804
2005 Miller LS, Sørensen OE, Liu PT, Jalian HR, Eshtiaghpour D, Behmanesh BE, Chung W, Starner TD, Kim J, Sieling PA, Ganz T, Modlin RL. TGF-alpha regulates TLR expression and function on epidermal keratinocytes. Journal of Immunology (Baltimore, Md. : 1950). 174: 6137-43. PMID 15879109 DOI: 10.4049/Jimmunol.174.10.6137  0.668
2005 Liu PT, Krutzik SR, Kim J, Modlin RL. Cutting edge: all-trans retinoic acid down-regulates TLR2 expression and function. Journal of Immunology (Baltimore, Md. : 1950). 174: 2467-70. PMID 15728448 DOI: 10.4049/Jimmunol.174.5.2467  0.787
2004 Doyle SE, O'Connell RM, Miranda GA, Vaidya SA, Chow EK, Liu PT, Suzuki S, Suzuki N, Modlin RL, Yeh WC, Lane TF, Cheng G. Toll-like receptors induce a phagocytic gene program through p38. The Journal of Experimental Medicine. 199: 81-90. PMID 14699082 DOI: 10.1084/Jem.20031237  0.623
2003 Krutzik SR, Ochoa MT, Sieling PA, Uematsu S, Ng YW, Legaspi A, Liu PT, Cole ST, Godowski PJ, Maeda Y, Sarno EN, Norgard MV, Brennan PJ, Akira S, Rea TH, et al. Activation and regulation of Toll-like receptors 2 and 1 in human leprosy. Nature Medicine. 9: 525-32. PMID 12692544 DOI: 10.1038/Nm864  0.787
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