| Year |
Citation |
Score |
| 2024 |
Jalali E, Wang F, Overbay BR, Miller MD, Shaaban KA, Ponomareva LV, Ye Q, Saghaeiannejad-Esfahani H, Bhardwaj M, Steele AD, Teijaro CN, Shen B, Van Lanen SG, She QB, Voss SR, ... ... Thorson JS, et al. Biochemical and Structural Studies of the Carminomycin 4--Methyltransferase DnrK. Journal of Natural Products. PMID 38412432 DOI: 10.1021/acs.jnatprod.3c00947 |
0.535 |
|
| 2023 |
Bhardwaj M, Cui Z, Daniel Hankore E, Moonschi FH, Saghaeiannejad Esfahani H, Kalkreuter E, Gui C, Yang D, Phillips GN, Thorson JS, Shen B, Van Lanen SG. A discrete intermediate for the biosynthesis of both the enediyne core and the anthraquinone moiety of enediyne natural products. Proceedings of the National Academy of Sciences of the United States of America. 120: e2220468120. PMID 36802426 DOI: 10.1073/pnas.2220468120 |
0.509 |
|
| 2020 |
Clinger JA, Wang X, Cai W, Zhu Y, Miller MD, Zhan CG, Van Lanen SG, Thorson JS, Phillips GN. The Crystal Structure of AbsH3: a Putative FAD-dependent Reductase in the Abyssomicin Biosynthesis Pathway. Proteins. PMID 32852843 DOI: 10.1002/Prot.25994 |
0.398 |
|
| 2020 |
Cui Z, Overbay J, Wang X, Liu X, Zhang Y, Bhardwaj M, Lemke A, Wiegmann D, Niro G, Thorson JS, Ducho C, Van Lanen SG. Pyridoxal-5'-phosphate-dependent alkyl transfer in nucleoside antibiotic biosynthesis. Nature Chemical Biology. PMID 32483377 DOI: 10.1038/S41589-020-0548-3 |
0.382 |
|
| 2020 |
Zhang Y, Zhang J, Ponomareva LV, Cui Z, Van Lanen SG, Thorson JS. Sugar-pirating as an enabling platform for the synthesis of 4,6-dideoxyhexoses. Journal of the American Chemical Society. PMID 32330028 DOI: 10.1021/Jacs.9B13766 |
0.377 |
|
| 2020 |
Huber TD, Clinger JA, Liu Y, Xu W, Miller MD, Phillips GN, Thorson JS. Methionine adenosyltransferase engineering to enable bioorthogonal platforms for AdoMet-utilizing enzymes. Acs Chemical Biology. PMID 32091873 DOI: 10.1021/Acschembio.9B00943 |
0.415 |
|
| 2019 |
Wang X, Elshahawi SI, Ponomareva LV, Ye Q, Liu Y, Copley GC, Hower JC, Hatcher BE, Kharel MK, Van Lanen SG, She QB, Voss SR, Thorson JS, Shaaban KA. Structure Determination, Functional Characterization, and Biosynthetic Implications of Nybomycin Metabolites from a Mining Reclamation Site-Associated . Journal of Natural Products. PMID 31833370 DOI: 10.1021/Acs.Jnatprod.9B01015 |
0.35 |
|
| 2019 |
Hughes R, Shaaban K, Ponomareva L, Horn J, Zhang C, Zhan CG, Voss SR, Leggas M, Thorson JS. OleD Loki as a catalyst for hydroxamate glycosylation. Chembiochem : a European Journal of Chemical Biology. PMID 31621997 DOI: 10.1002/Cbic.201900601 |
0.355 |
|
| 2019 |
Zhang Y, Ye Q, Ponomareva LV, Cao Y, Liu Y, Cui Z, Van Lanen SG, Voss SR, She QB, Thorson JS. Total synthesis of griseusins and elucidation of the griseusin mechanism of action. Chemical Science. 10: 7641-7648. PMID 31583069 DOI: 10.1039/C9Sc02289A |
0.38 |
|
| 2019 |
Noriler SA, Savi DC, Ponomareva LV, Rohr J, Thorson JS, Rodrigues R, Glienke C, Shaaban KA. Vochysiamides A and B: Two new bioactive carboxamides produced by the new species Diaporthe vochysiae. Fitoterapia. 104273. PMID 31344395 DOI: 10.1016/J.Fitote.2019.104273 |
0.302 |
|
| 2019 |
Wang X, Abbas M, Zhang Y, Elshahawi SI, Ponomareva LV, Cui Z, Van Lanen SG, Sajid I, Voss SR, Shaaban KA, Thorson JS. Baraphenazines A-G, Divergent Fused Phenazine-Based Metabolites from a Himalayan Streptomyces. Journal of Natural Products. PMID 31117525 DOI: 10.1021/Acs.Jnatprod.9B00289 |
0.309 |
|
| 2019 |
Biecker AL, Liu X, Thorson JS, Yang Z, Van Lanen SG. Biosynthetic and Synthetic Strategies for Assembling Capuramycin-Type Antituberculosis Antibiotics. Molecules (Basel, Switzerland). 24. PMID 30691073 DOI: 10.3390/Molecules24030433 |
0.314 |
|
| 2018 |
Savi DC, Shaaban KA, Gos FMW, Thorson JS, Glienke C, Rohr J. Secondary metabolites produced by Microbacterium sp. LGMB471 with antifungal activity against the phytopathogen Phyllosticta citricarpa. Folia Microbiologica. PMID 30565048 DOI: 10.1007/S12223-018-00668-X |
0.316 |
|
| 2018 |
Abbas M, Elshahawi SI, Wang X, Ponomareva LV, Sajid I, Shaaban KA, Thorson JS. Puromycins B-E, Naturally Occurring Amino-Nucleosides Produced by the Himalayan Isolate Streptomyces sp. PU-14G. Journal of Natural Products. PMID 30418763 DOI: 10.1021/Acs.Jnatprod.8B00720 |
0.364 |
|
| 2018 |
Cui Z, Liu X, Overbay J, Cai W, Wang X, Lemke A, Wiegmann D, Niro G, Thorson JS, Ducho C, Van Lanen SG. Enzymatic Synthesis of the Ribosylated Glycyl-Uridine Disaccharide Core of Peptidyl Nucleoside Antibiotics. The Journal of Organic Chemistry. PMID 29768920 DOI: 10.1021/Acs.Joc.8B00855 |
0.413 |
|
| 2018 |
Cui Z, Wang XC, Liu X, Lemke A, Koppermann S, Ducho C, Rohr J, Thorson JS, Van Lanen SG. Self-Resistance During Muraymycin Biosynthesis: A Complementary Nucleotidyltransferase and Phosphotransferase with Identical Modification Sites and Distinct Temporal Order. Antimicrobial Agents and Chemotherapy. PMID 29735559 DOI: 10.1128/Aac.00193-18 |
0.427 |
|
| 2018 |
Cui Z, Wang X, Koppermann S, Thorson JS, Ducho C, Van Lanen SG. Antibacterial Muraymycins from Mutant Strains of Streptomyces sp. NRRL 30471. Journal of Natural Products. PMID 29553733 DOI: 10.1021/Acs.Jnatprod.7B01054 |
0.329 |
|
| 2018 |
de Medeiros AG, Savi DC, Mitra P, Shaaban KA, Jha AK, Thorson JS, Rohr J, Glienke C. Bioprospecting of Diaporthe terebinthifolii LGMF907 for antimicrobial compounds. Folia Microbiologica. PMID 29497981 DOI: 10.1007/S12223-018-0587-2 |
0.324 |
|
| 2018 |
Koppermann S, Cui Z, Fischer PD, Wang X, Ludwig J, Thorson JS, Van Lanen SG, Ducho C. Insights into the Target Interaction of Naturally Occurring Muraymycin Nucleoside Antibiotics. Chemmedchem. PMID 29438582 DOI: 10.1002/Cmdc.201700793 |
0.383 |
|
| 2017 |
Elshahawi SI, Cao H, Shaaban KA, Ponomareva LV, Subramanian T, Farman ML, Spielmann HP, Phillips GN, Thorson JS, Singh S. Structure and specificity of a permissive bacterial C-prenyltransferase. Nature Chemical Biology. PMID 28166207 DOI: 10.1038/Nchembio.2285 |
0.671 |
|
| 2017 |
Wang X, Zhang Y, Ponomareva LV, Qiu Q, Woodcock R, Elshahawi SI, Chen X, Zhou Z, Hatcher BE, Hower JC, Zhan CG, Parkin S, Kharel MK, Voss SR, Shaaban KA, ... Thorson JS, et al. Mccrearamycins A-D, Geldanamycin-Derived Cyclopentenone Macrolactams from an Eastern Kentucky Abandoned Coal Mine Microbe. Angewandte Chemie (International Ed. in English). PMID 28140487 DOI: 10.1002/Anie.201612447 |
0.342 |
|
| 2017 |
Hughes RR, Shaaban KA, Zhang J, Cao H, Phillips GN, Thorson JS. OleD Loki as a Catalyst for Tertiary Amine and Hydroxamate Glycosylation. Chembiochem : a European Journal of Chemical Biology. PMID 28067448 DOI: 10.1002/Cbic.201600676 |
0.334 |
|
| 2016 |
Zhang J, Hughes RR, Saunders MA, Elshahawi SI, Ponomareva LV, Zhang Y, Winchester SR, Scott SA, Sunkara M, Morris AJ, Prendergast MA, Shaaban KA, Thorson JS. Identification of Neuroprotective Spoxazomicin and Oxachelin Glycosides via Chemoenzymatic Glycosyl-Scanning. Journal of Natural Products. PMID 28029796 DOI: 10.1021/Acs.Jnatprod.6B00949 |
0.426 |
|
| 2016 |
Shaaban KA, Saunders MA, Zhang Y, Tran T, Elshahawi SI, Ponomareva LV, Wang X, Zhang J, Copley GC, Sunkara M, Kharel MK, Morris AJ, Hower JC, Tremblay MS, Prendergast MA, ... Thorson JS, et al. Spoxazomicin D and Oxachelin C, Potent Neuroprotective Carboxamides from the Appalachian Coal Fire-Associated Isolate Streptomyces sp. RM-14-6. Journal of Natural Products. PMID 28029795 DOI: 10.1021/Acs.Jnatprod.6B00948 |
0.572 |
|
| 2016 |
Cai W, Wang X, Elshahawi SI, Ponomareva LV, Liu X, McErlean MR, Cui Z, Arlinghaus AL, Thorson JS, Van Lanen SG. Antibacterial and Cytotoxic Actinomycins Y6-Y9 and Zp from Streptomyces sp. Strain Gö-GS12. Journal of Natural Products. PMID 27736087 DOI: 10.1021/Acs.Jnatprod.6B00742 |
0.311 |
|
| 2016 |
Huber TD, Johnson BR, Zhang J, Thorson JS. AdoMet analog synthesis and utilization: current state of the art. Current Opinion in Biotechnology. 42: 189-197. PMID 27506965 DOI: 10.1016/J.Copbio.2016.07.005 |
0.362 |
|
| 2016 |
Huber TD, Wang F, Singh S, Johnson BR, Zhang J, Sunkara M, Van Lanen SG, Morris AJ, Phillips GN, Thorson JS. Functional AdoMet isosteres resistant to classical AdoMet degradation pathways. Acs Chemical Biology. PMID 27351335 DOI: 10.1021/Acschembio.6B00348 |
0.707 |
|
| 2016 |
Cao H, Tan K, Wang F, Bigelow L, Yennamalli RM, Jedrzejczak R, Babnigg G, Bingman CA, Joachimiak A, Kharel MK, Singh S, Thorson JS, Phillips GN. Structural dynamics of a methionine γ-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate. Structural Dynamics (Melville, N.Y.). 3: 034702. PMID 27191010 DOI: 10.1063/1.4948539 |
0.69 |
|
| 2016 |
Han L, Singh S, Thorson JS, Phillips GN. Loop dynamics of thymidine diphosphate-rhamnose 3'-O-methyltransferase (CalS11), an enzyme in calicheamicin biosynthesis. Structural Dynamics (Melville, N.Y.). 3: 012004. PMID 26958582 DOI: 10.1063/1.4941368 |
0.694 |
|
| 2015 |
Zhang J, Ponomareva LV, Nandurkar NS, Yuan Y, Fang L, Zhan CG, Thorson JS. Influence of Sugar Amine Regiochemistry on Digitoxigenin Neoglycoside Anticancer Activity. Acs Medicinal Chemistry Letters. 6: 1053-8. PMID 26487911 DOI: 10.1021/Acsmedchemlett.5B00120 |
0.322 |
|
| 2015 |
Peltier-Pain P, Singh S, Thorson JS. Characterization of early enzymes involved in TDP-aminodideoxypentose biosynthesis en route to indolocarbazole AT2433. Chembiochem : a European Journal of Chemical Biology. PMID 26289554 DOI: 10.1002/Cbic.201500365 |
0.686 |
|
| 2015 |
Singh S, Michalska K, Bigelow L, Endres M, Kharel MK, Babnigg G, Yennamalli RM, Bingman CA, Joachimiak A, Thorson JS, Phillips GN. Structural Characterization of CalS8, a TDP-alpha-D-Glucose Dehydrogenase Involved in Calicheamicin Aminodideoxypentose Biosynthesis. The Journal of Biological Chemistry. PMID 26240141 DOI: 10.1074/Jbc.M115.673459 |
0.703 |
|
| 2015 |
Zhang Y, Ye Q, Wang X, She QB, Thorson JS. A Divergent Enantioselective Strategy for the Synthesis of Griseusins. Angewandte Chemie (International Ed. in English). PMID 26230189 DOI: 10.1002/Anie.201505022 |
0.338 |
|
| 2015 |
Shaaban KA, Elshahawi SI, Wang X, Horn J, Kharel MK, Leggas M, Thorson JS. Cytotoxic Indolocarbazoles from Actinomadura melliaura ATCC 39691. Journal of Natural Products. 78: 1723-9. PMID 26091285 DOI: 10.1021/Acs.Jnatprod.5B00429 |
0.329 |
|
| 2015 |
Singh S, Kim Y, Wang F, Bigelow L, Endres M, Kharel MK, Babnigg G, Bingman CA, Joachimiak A, Thorson JS, Phillips GN. Structural characterization of AtmS13, a putative sugar aminotransferase involved in indolocarbazole AT2433 aminopentose biosynthesis. Proteins. 83: 1547-54. PMID 26061967 DOI: 10.1002/Prot.24844 |
0.71 |
|
| 2015 |
Wang F, Singh S, Xu W, Helmich KE, Miller MD, Cao H, Bingman CA, Thorson JS, Phillips GN. Structural Basis for the Stereochemical Control of Amine Installation in Nucleotide Sugar Aminotransferases. Acs Chemical Biology. PMID 26023720 DOI: 10.1021/Acschembio.5B00244 |
0.713 |
|
| 2015 |
Wang X, Reynolds AR, Elshahawi SI, Shaaban KA, Ponomareva LV, Saunders MA, Elgumati IS, Zhang Y, Copley GC, Hower JC, Sunkara M, Morris AJ, Kharel MK, Van Lanen SG, Prendergast MA, ... Thorson JS, et al. Terfestatins B and C, New p-Terphenyl Glycosides Produced by Streptomyces sp. RM-5-8. Organic Letters. 17: 2796-9. PMID 25961722 DOI: 10.1021/Acs.Orglett.5B01203 |
0.308 |
|
| 2015 |
Cai W, Goswami A, Yang Z, Liu X, Green KD, Barnard-Britson S, Baba S, Funabashi M, Nonaka K, Sunkara M, Morris AJ, Spork AP, Ducho C, Garneau-Tsodikova S, Thorson JS, et al. The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE. The Journal of Biological Chemistry. 290: 13710-24. PMID 25855790 DOI: 10.1074/Jbc.M115.646414 |
0.381 |
|
| 2015 |
Elshahawi SI, Shaaban KA, Kharel MK, Thorson JS. A comprehensive review of glycosylated bacterial natural products. Chemical Society Reviews. 44: 7591-697. PMID 25735878 DOI: 10.1039/C4Cs00426D |
0.368 |
|
| 2015 |
Tam HK, Härle J, Gerhardt S, Rohr J, Wang G, Thorson JS, Bigot A, Lutterbeck M, Seiche W, Breit B, Bechthold A, Einsle O. Structural characterization of O- and C-glycosylating variants of the landomycin glycosyltransferase LanGT2. Angewandte Chemie (International Ed. in English). 54: 2811-5. PMID 25581707 DOI: 10.1002/Anie.201409792 |
0.381 |
|
| 2014 |
Nandurkar NS, Zhang J, Ye Q, Ponomareva LV, She QB, Thorson JS. The identification of perillyl alcohol glycosides with improved antiproliferative activity. Journal of Medicinal Chemistry. 57: 7478-84. PMID 25121720 DOI: 10.1021/Jm500870U |
0.301 |
|
| 2014 |
Elshahawi SI, Ramelot TA, Seetharaman J, Chen J, Singh S, Yang Y, Pederson K, Kharel MK, Xiao R, Lew S, Yennamalli RM, Miller MD, Wang F, Tong L, Montelione GT, ... ... Thorson JS, et al. Structure-guided functional characterization of enediyne self-sacrifice resistance proteins, CalU16 and CalU19. Acs Chemical Biology. 9: 2347-58. PMID 25079510 DOI: 10.1021/Cb500327M |
0.673 |
|
| 2014 |
Goff RD, Thorson JS. Neoglycosylation and neoglycorandomization: Enabling tools for the discovery of novel glycosylated bioactive probes and early stage leads. Medchemcomm. 5: 1036-1047. PMID 25071927 DOI: 10.1039/C4Md00117F |
0.738 |
|
| 2014 |
Chen Z, Zhang J, Singh S, Peltier-Pain P, Thorson JS, Hinds BJ. Functionalized anodic aluminum oxide membrane-electrode system for enzyme immobilization. Acs Nano. 8: 8104-12. PMID 25025628 DOI: 10.1021/Nn502181K |
0.687 |
|
| 2014 |
Singh S, Nandurkar NS, Thorson JS. Characterization of the calicheamicin orsellinate C2-O-methyltransferase CalO6. Chembiochem : a European Journal of Chemical Biology. 15: 1418-21. PMID 24978950 DOI: 10.1002/Cbic.201402119 |
0.686 |
|
| 2014 |
Singh S, Peltier-Pain P, Tonelli M, Thorson JS. A general NMR-based strategy for the in situ characterization of sugar-nucleotide-dependent biosynthetic pathways. Organic Letters. 16: 3220-3. PMID 24911465 DOI: 10.1021/Ol501241A |
0.696 |
|
| 2014 |
Zhang J, Singh S, Hughes RR, Zhou M, Sunkara M, Morris AJ, Thorson JS. A simple strategy for glycosyltransferase-catalyzed aminosugar nucleotide synthesis. Chembiochem : a European Journal of Chemical Biology. 15: 647-52. PMID 24677528 DOI: 10.1002/Cbic.201300779 |
0.69 |
|
| 2014 |
Wang F, Singh S, Zhang J, Huber TD, Helmich KE, Sunkara M, Hurley KA, Goff RD, Bingman CA, Morris AJ, Thorson JS, Phillips GN. Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus. The Febs Journal. 281: 4224-39. PMID 24649856 DOI: 10.1111/Febs.12784 |
0.812 |
|
| 2014 |
Singh S, Zhang J, Huber TD, Sunkara M, Hurley K, Goff RD, Wang G, Zhang W, Liu C, Rohr J, Van Lanen SG, Morris AJ, Thorson JS. Facile chemoenzymatic strategies for the synthesis and utilization of S-adenosyl-(L)-methionine analogues. Angewandte Chemie (International Ed. in English). 53: 3965-9. PMID 24616228 DOI: 10.1002/Anie.201308272 |
0.807 |
|
| 2014 |
Wang X, Elshahawi SI, Shaaban KA, Fang L, Ponomareva LV, Zhang Y, Copley GC, Hower JC, Zhan CG, Kharel MK, Thorson JS. Ruthmycin, a new tetracyclic polyketide from Streptomyces sp. RM-4-15. Organic Letters. 16: 456-9. PMID 24341358 DOI: 10.1021/Ol4033418 |
0.328 |
|
| 2014 |
Shaaban KA, Singh S, Elshahawi SI, Wang X, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. Venturicidin C, a new 20-membered macrolide produced by Streptomyces sp. TS-2-2. The Journal of Antibiotics. 67: 223-30. PMID 24252813 DOI: 10.1038/Ja.2013.113 |
0.668 |
|
| 2014 |
Shaaban KA, Singh S, Elshahawi SI, Wang X, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. The native production of the sesquiterpene isopterocarpolone by Streptomyces sp. RM-14-6. Natural Product Research. 28: 337-9. PMID 24237421 DOI: 10.1080/14786419.2013.855932 |
0.695 |
|
| 2014 |
Chen Z, Zhang J, Singh S, Peltier-Pain P, Thorson JS, Hinds BJ. Functionalized anodic aluminum oxide membrane-electrode system for enzyme immobilization Acs Nano. 8: 8104-8112. DOI: 10.1021/nn502181k |
0.608 |
|
| 2013 |
Zhang J, Ponomareva LV, Marchillo K, Zhou M, Andes DR, Thorson JS. Synthesis and antibacterial activity of doxycycline neoglycosides. Journal of Natural Products. 76: 1627-36. PMID 23987662 DOI: 10.1021/Np4003096 |
0.332 |
|
| 2013 |
Wang X, Shaaban KA, Elshahawi SI, Ponomareva LV, Sunkara M, Zhang Y, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. Frenolicins C-G, pyranonaphthoquinones from Streptomyces sp. RM-4-15. Journal of Natural Products. 76: 1441-7. PMID 23944931 DOI: 10.1021/Np400231R |
0.346 |
|
| 2013 |
Singh S, Chang A, Helmich KE, Bingman CA, Wrobel RL, Beebe ET, Makino S, Aceti DJ, Dyer K, Hura GL, Sunkara M, Morris AJ, Phillips GN, Thorson JS. Structural and functional characterization of CalS11, a TDP-rhamnose 3'-O-methyltransferase involved in calicheamicin biosynthesis. Acs Chemical Biology. 8: 1632-9. PMID 23662776 DOI: 10.1021/Cb400068K |
0.708 |
|
| 2013 |
Gantt RW, Peltier-Pain P, Singh S, Zhou M, Thorson JS. Broadening the scope of glycosyltransferase-catalyzed sugar nucleotide synthesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 7648-53. PMID 23610417 DOI: 10.1073/Pnas.1220220110 |
0.686 |
|
| 2013 |
Wang F, Zhou M, Singh S, Yennamalli RM, Bingman CA, Thorson JS, Phillips GN. Crystal structure of SsfS6, the putative C-glycosyltransferase involved in SF2575 biosynthesis. Proteins. 81: 1277-82. PMID 23526584 DOI: 10.1002/Prot.24289 |
0.686 |
|
| 2013 |
Zhou M, Hamza A, Zhan CG, Thorson JS. Assessing the regioselectivity of OleD-catalyzed glycosylation with a diverse set of acceptors. Journal of Natural Products. 76: 279-86. PMID 23360118 DOI: 10.1021/Np300890H |
0.408 |
|
| 2012 |
Zhou M, Hou Y, Hamza A, Pain C, Zhan CG, Bugni TS, Thorson JS. Probing the regiospecificity of enzyme-catalyzed steroid glycosylation. Organic Letters. 14: 5424-7. PMID 23075289 DOI: 10.1021/Ol3024924 |
0.349 |
|
| 2012 |
Gantt RW, Thorson JS. High-throughput colorimetric assays for nucleotide sugar formation and glycosyl transfer. Methods in Enzymology. 516: 345-60. PMID 23034237 DOI: 10.1016/B978-0-12-394291-3.00009-5 |
0.384 |
|
| 2012 |
Peltier-Pain P, Marchillo K, Zhou M, Andes DR, Thorson JS. Natural product disaccharide engineering through tandem glycosyltransferase catalysis reversibility and neoglycosylation. Organic Letters. 14: 5086-9. PMID 22984807 DOI: 10.1021/Ol3023374 |
0.383 |
|
| 2012 |
Singh S, Phillips GN, Thorson JS. The structural biology of enzymes involved in natural product glycosylation. Natural Product Reports. 29: 1201-37. PMID 22688446 DOI: 10.1039/C2Np20039B |
0.727 |
|
| 2012 |
Goff RD, Thorson JS. Enhancement of cyclopamine via conjugation with nonmetabolic sugars. Organic Letters. 14: 2454-7. PMID 22540932 DOI: 10.1021/Ol300703Z |
0.716 |
|
| 2012 |
Shen B, Thorson JS. Expanding nature's chemical repertoire through metabolic engineering and biocatalysis. Current Opinion in Chemical Biology. 16: 99-100. PMID 22464247 DOI: 10.1016/J.Cbpa.2012.03.006 |
0.489 |
|
| 2011 |
Chang A, Singh S, Helmich KE, Goff RD, Bingman CA, Thorson JS, Phillips GN. Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity. Proceedings of the National Academy of Sciences of the United States of America. 108: 17649-54. PMID 21987796 DOI: 10.1073/Pnas.1108484108 |
0.814 |
|
| 2011 |
Gantt RW, Peltier-Pain P, Thorson JS. Enzymatic methods for glyco(diversification/randomization) of drugs and small molecules. Natural Product Reports. 28: 1811-53. PMID 21901218 DOI: 10.1039/C1Np00045D |
0.362 |
|
| 2011 |
Gantt RW, Peltier-Pain P, Cournoyer WJ, Thorson JS. Using simple donors to drive the equilibria of glycosyltransferase-catalyzed reactions. Nature Chemical Biology. 7: 685-91. PMID 21857660 DOI: 10.1038/Nchembio.638 |
0.366 |
|
| 2011 |
Lee HS, Thorson JS. Development of a universal glycosyltransferase assay amenable to high-throughput formats. Analytical Biochemistry. 418: 85-8. PMID 21741952 DOI: 10.1016/J.Ab.2011.06.016 |
0.684 |
|
| 2011 |
Peltier-Pain P, Timmons SC, Grandemange A, Benoit E, Thorson JS. Warfarin glycosylation invokes a switch from anticoagulant to anticancer activity. Chemmedchem. 6: 1347-50. PMID 21714096 DOI: 10.1002/Cmdc.201100178 |
0.783 |
|
| 2011 |
Chang A, Singh S, Phillips GN, Thorson JS. Glycosyltransferase structural biology and its role in the design of catalysts for glycosylation. Current Opinion in Biotechnology. 22: 800-8. PMID 21592771 DOI: 10.1016/J.Copbio.2011.04.013 |
0.675 |
|
| 2011 |
Singh S, Chang A, Goff RD, Bingman CA, Grüschow S, Sherman DH, Phillips GN, Thorson JS. Structural characterization of the mitomycin 7-O-methyltransferase. Proteins. 79: 2181-8. PMID 21538548 DOI: 10.1002/Prot.23040 |
0.801 |
|
| 2011 |
Zhou M, Thorson JS. Asymmetric enzymatic glycosylation of mitoxantrone. Organic Letters. 13: 2786-8. PMID 21528870 DOI: 10.1021/Ol200977U |
0.365 |
|
| 2011 |
Goff RD, Singh S, Thorson JS. Glycosyloxyamine neoglycosylation: a model study using calicheamicin. Chemmedchem. 6: 774-6. PMID 21520418 DOI: 10.1002/Cmdc.201100028 |
0.804 |
|
| 2011 |
Chang A, Singh S, Bingman CA, Thorson JS, Phillips GN. Structural characterization of CalO1: a putative orsellinic acid methyltransferase in the calicheamicin-biosynthetic pathway. Acta Crystallographica. Section D, Biological Crystallography. 67: 197-203. PMID 21358050 DOI: 10.1107/S090744491100360X |
0.697 |
|
| 2011 |
Moretti R, Chang A, Peltier-Pain P, Bingman CA, Phillips GN, Thorson JS. Expanding the nucleotide and sugar 1-phosphate promiscuity of nucleotidyltransferase RmlA via directed evolution. The Journal of Biological Chemistry. 286: 13235-43. PMID 21317292 DOI: 10.1074/Jbc.M110.206433 |
0.397 |
|
| 2011 |
Williams GJ, Yang J, Zhang C, Thorson JS. Recombinant E. coli prototype strains for in vivo glycorandomization. Acs Chemical Biology. 6: 95-100. PMID 20886903 DOI: 10.1021/Cb100267K |
0.689 |
|
| 2010 |
Goff RD, Thorson JS. Assessment of chemoselective neoglycosylation methods using chlorambucil as a model. Journal of Medicinal Chemistry. 53: 8129-39. PMID 20973561 DOI: 10.1021/Jm101024J |
0.725 |
|
| 2010 |
Horsman GP, Chen Y, Thorson JS, Shen B. Polyketide synthase chemistry does not direct biosynthetic divergence between 9- and 10-membered enediynes. Proceedings of the National Academy of Sciences of the United States of America. 107: 11331-5. PMID 20534556 DOI: 10.1073/Pnas.1003442107 |
0.566 |
|
| 2009 |
Goff RD, Thorson JS. Enhancing the divergent activities of betulinic acid via neoglycosylation. Organic Letters. 11: 461-4. PMID 19102682 DOI: 10.1021/Ol8025704 |
0.703 |
|
| 2009 |
Williams GJ, Thorson JS. Natural product glycosyltransferases: properties and applications. Advances in Enzymology and Related Areas of Molecular Biology. 76: 55-119. PMID 18990828 DOI: 10.1002/9780470392881.Ch2 |
0.569 |
|
| 2009 |
McCoy JG, Johnson HD, Singh S, Bingman CA, Lei IK, Thorson JS, Phillips GN. Structural characterization of CalO2: a putative orsellinic acid P450 oxidase in the calicheamicin biosynthetic pathway. Proteins. 74: 50-60. PMID 18561189 DOI: 10.1002/Prot.22131 |
0.712 |
|
| 2008 |
Johnson HD, Thorson JS. Characterization of CalE10, the N-oxidase involved in calicheamicin hydroxyaminosugar formation. Journal of the American Chemical Society. 130: 17662-3. PMID 19055330 DOI: 10.1021/Ja807557A |
0.304 |
|
| 2008 |
Gantt RW, Goff RD, Williams GJ, Thorson JS. Probing the aglycon promiscuity of an engineered glycosyltransferase. Angewandte Chemie (International Ed. in English). 47: 8889-92. PMID 18924204 DOI: 10.1002/Anie.200803508 |
0.81 |
|
| 2008 |
Zhang C, Moretti R, Jiang J, Thorson JS. The in vitro characterization of polyene glycosyltransferases AmphDI and NysDI. Chembiochem : a European Journal of Chemical Biology. 9: 2506-14. PMID 18798210 DOI: 10.1002/Cbic.200800349 |
0.604 |
|
| 2008 |
Zhang C, Bitto E, Goff RD, Singh S, Bingman CA, Griffith BR, Albermann C, Phillips GN, Thorson JS. Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis. Chemistry & Biology. 15: 842-53. PMID 18721755 DOI: 10.1016/J.Chembiol.2008.06.011 |
0.791 |
|
| 2008 |
Williams GJ, Gantt RW, Thorson JS. The impact of enzyme engineering upon natural product glycodiversification. Current Opinion in Chemical Biology. 12: 556-64. PMID 18678278 DOI: 10.1016/J.Cbpa.2008.07.013 |
0.632 |
|
| 2008 |
Singh S, McCoy JG, Zhang C, Bingman CA, Phillips GN, Thorson JS. Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM. The Journal of Biological Chemistry. 283: 22628-36. PMID 18502766 DOI: 10.1074/Jbc.M800503200 |
0.751 |
|
| 2008 |
Timmons SC, Thorson JS. Increasing carbohydrate diversity via amine oxidation: aminosugar, hydroxyaminosugar, nitrososugar, and nitrosugar biosynthesis in bacteria. Current Opinion in Chemical Biology. 12: 297-305. PMID 18424273 DOI: 10.1016/J.Cbpa.2008.03.017 |
0.793 |
|
| 2008 |
Moretti R, Donato LJ, Brezinski ML, Stafford RL, Hoff H, Thorson JS, Dervan PB, Ansari AZ. Targeted chemical wedges reveal the role of allosteric DNA modulation in protein-DNA assembly. Acs Chemical Biology. 3: 220-9. PMID 18422304 DOI: 10.1021/Cb700258R |
0.483 |
|
| 2008 |
Williams GJ, Goff RD, Zhang C, Thorson JS. Optimizing glycosyltransferase specificity via "hot spot" saturation mutagenesis presents a catalyst for novobiocin glycorandomization. Chemistry & Biology. 15: 393-401. PMID 18420146 DOI: 10.1016/J.Chembiol.2008.02.017 |
0.779 |
|
| 2008 |
Moretti R, Thorson JS. A comparison of sugar indicators enables a universal high-throughput sugar-1-phosphate nucleotidyltransferase assay. Analytical Biochemistry. 377: 251-8. PMID 18387352 DOI: 10.1016/J.Ab.2008.03.018 |
0.348 |
|
| 2008 |
Gao Q, Thorson JS. The biosynthetic genes encoding for the production of the dynemicin enediyne core in Micromonospora chersina ATCC53710. Fems Microbiology Letters. 282: 105-14. PMID 18328078 DOI: 10.1111/J.1574-6968.2008.01112.X |
0.317 |
|
| 2008 |
Williams GJ, Thorson JS. A high-throughput fluorescence-based glycosyltransferase screen and its application in directed evolution. Nature Protocols. 3: 357-62. PMID 18323806 DOI: 10.1038/Nprot.2007.538 |
0.565 |
|
| 2008 |
Bitto E, Huang Y, Bingman CA, Singh S, Thorson JS, Phillips GN. The structure of flavin-dependent tryptophan 7-halogenase RebH. Proteins. 70: 289-93. PMID 17876823 DOI: 10.1002/Prot.21627 |
0.721 |
|
| 2007 |
Williams GJ, Zhang C, Thorson JS. Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution. Nature Chemical Biology. 3: 657-62. PMID 17828251 DOI: 10.1038/Nchembio.2007.28 |
0.713 |
|
| 2007 |
Griffith BR, Krepel C, Fu X, Blanchard S, Ahmed A, Edmiston CE, Thorson JS. Model for antibiotic optimization via neoglycosylation: synthesis of liponeoglycopeptides active against VRE. Journal of the American Chemical Society. 129: 8150-5. PMID 17564440 DOI: 10.1021/Ja068602R |
0.337 |
|
| 2007 |
Hui JP, Yang J, Thorson JS, Soo EC. Selective detection of sugar phosphates by capillary electrophoresis/mass spectrometry and its application to an engineered E. coli host. Chembiochem : a European Journal of Chemical Biology. 8: 1180-8. PMID 17562551 DOI: 10.1002/Cbic.200700116 |
0.321 |
|
| 2007 |
Moretti R, Thorson JS. Enhancing the latent nucleotide triphosphate flexibility of the glucose-1-phosphate thymidylyltransferase RmlA. The Journal of Biological Chemistry. 282: 16942-7. PMID 17434871 DOI: 10.1074/Jbc.M701951200 |
0.375 |
|
| 2007 |
Zhang C, Fu Q, Albermann C, Li L, Thorson JS. The in vitro characterization of the erythronolide mycarosyltransferase EryBV and its utility in macrolide diversification. Chembiochem : a European Journal of Chemical Biology. 8: 385-90. PMID 17262863 DOI: 10.1002/Cbic.200600509 |
0.747 |
|
| 2006 |
Zhang C, Albermann C, Fu X, Thorson JS. The in vitro characterization of the iterative avermectin glycosyltransferase AveBI reveals reaction reversibility and sugar nucleotide flexibility. Journal of the American Chemical Society. 128: 16420-1. PMID 17177349 DOI: 10.1021/Ja065950K |
0.776 |
|
| 2006 |
Singh S, Hager MH, Zhang C, Griffith BR, Lee MS, Hallenga K, Markley JL, Thorson JS. Structural insight into the self-sacrifice mechanism of enediyne resistance. Acs Chemical Biology. 1: 451-60. PMID 17168523 DOI: 10.1021/Cb6002898 |
0.738 |
|
| 2006 |
Griffith BR, Thorson JS. A sweet success for substrate engineering. Nature Chemical Biology. 2: 659-60. PMID 17108980 DOI: 10.1038/Nchembio1206-659 |
0.364 |
|
| 2006 |
Ahmed A, Peters NR, Fitzgerald MK, Watson JA, Hoffmann FM, Thorson JS. Colchicine glycorandomization influences cytotoxicity and mechanism of action. Journal of the American Chemical Society. 128: 14224-5. PMID 17076473 DOI: 10.1021/Ja064686S |
0.389 |
|
| 2006 |
Zhang C, Griffith BR, Fu Q, Albermann C, Fu X, Lee IK, Li L, Thorson JS. Exploiting the reversibility of natural product glycosyltransferase-catalyzed reactions. Science (New York, N.Y.). 313: 1291-4. PMID 16946071 DOI: 10.1126/Science.1130028 |
0.78 |
|
| 2006 |
Gao Q, Zhang C, Blanchard S, Thorson JS. Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus. Chemistry & Biology. 13: 733-43. PMID 16873021 DOI: 10.1016/J.Chembiol.2006.05.009 |
0.56 |
|
| 2006 |
Biggins JB, Prudent JR, Marshall DJ, Thorson JS. A continuous assay for DNA cleavage using molecular break lights. Methods in Molecular Biology (Clifton, N.J.). 335: 83-92. PMID 16785622 DOI: 10.1385/1-59745-069-3:83 |
0.667 |
|
| 2006 |
Blanchard S, Thorson JS. Enzymatic tools for engineering natural product glycosylation. Current Opinion in Chemical Biology. 10: 263-71. PMID 16675288 DOI: 10.1016/J.Cbpa.2006.04.001 |
0.404 |
|
| 2006 |
Zhang C, Albermann C, Fu X, Peters NR, Chisholm JD, Zhang G, Gilbert EJ, Wang PG, Van Vranken DL, Thorson JS. RebG- and RebM-catalyzed indolocarbazole diversification. Chembiochem : a European Journal of Chemical Biology. 7: 795-804. PMID 16575939 DOI: 10.1002/Cbic.200500504 |
0.802 |
|
| 2006 |
Borisova SA, Zhang C, Takahashi H, Zhang H, Wong AW, Thorson JS, Liu HW. Substrate specificity of the macrolide-glycosylating enzyme pair DesVII/DesVIII: opportunities, limitations, and mechanistic hypotheses. Angewandte Chemie (International Ed. in English). 45: 2748-53. PMID 16538696 DOI: 10.1002/Anie.200503195 |
0.673 |
|
| 2006 |
Zhang C, Weller RL, Thorson JS, Rajski SR. Natural product diversification using a non-natural cofactor analogue of S-adenosyl-L-methionine. Journal of the American Chemical Society. 128: 2760-1. PMID 16506729 DOI: 10.1021/Ja056231T |
0.617 |
|
| 2005 |
Bililign T, Griffith BR, Thorson JS. Structure, activity, synthesis and biosynthesis of aryl-C-glycosides. Natural Product Reports. 22: 742-60. PMID 16311633 DOI: 10.1039/B407364A |
0.355 |
|
| 2005 |
Langenhan JM, Griffith BR, Thorson JS. Neoglycorandomization and chemoenzymatic glycorandomization: two complementary tools for natural product diversification. Journal of Natural Products. 68: 1696-711. PMID 16309329 DOI: 10.1021/Np0502084 |
0.761 |
|
| 2005 |
Griffith BR, Langenhan JM, Thorson JS. 'Sweetening' natural products via glycorandomization. Current Opinion in Biotechnology. 16: 622-30. PMID 16226456 DOI: 10.1016/J.Copbio.2005.10.002 |
0.765 |
|
| 2005 |
Langenhan JM, Peters NR, Guzei IA, Hoffmann FM, Thorson JS. Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization. Proceedings of the National Academy of Sciences of the United States of America. 102: 12305-10. PMID 16105948 DOI: 10.1073/Pnas.0503270102 |
0.724 |
|
| 2005 |
Yang J, Fu X, Liao J, Liu L, Thorson JS. Structure-based engineering of E. coli galactokinase as a first step toward in vivo glycorandomization. Chemistry & Biology. 12: 657-64. PMID 15975511 DOI: 10.1016/J.Chembiol.2005.04.009 |
0.414 |
|
| 2005 |
Fu X, Albermann C, Zhang C, Thorson JS. Diversifying vancomycin via chemoenzymatic strategies. Organic Letters. 7: 1513-5. PMID 15816740 DOI: 10.1021/Ol0501626 |
0.772 |
|
| 2005 |
Galm U, Hager MH, Van Lanen SG, Ju J, Thorson JS, Shen B. Antitumor antibiotics: bleomycin, enediynes, and mitomycin. Chemical Reviews. 105: 739-58. PMID 15700963 DOI: 10.1021/Cr030117G |
0.478 |
|
| 2005 |
Langenhan JM, Thorson JS. Recent carbohydrate-based chemoselective ligation applications Current Organic Synthesis. 2: 59-81. DOI: 10.2174/1570179052996937 |
0.73 |
|
| 2004 |
Fu X, Langenhan JM, Thorson JS. Combinatorial chemoenzymatic strategies for in vitro glycorandomization: Efforts toward antibiotic optimization. Discovery Medicine. 4: 111-4. PMID 20705004 |
0.736 |
|
| 2004 |
Yang J, Liu L, Thorson JS. Structure-based enhancement of the first anomeric glucokinase. Chembiochem : a European Journal of Chemical Biology. 5: 992-6. PMID 15239058 DOI: 10.1002/Cbic.200400041 |
0.3 |
|
| 2004 |
Hoffmeister D, Thorson JS. Mechanistic implications of Escherichia coli galactokinase structure-based engineering. Chembiochem : a European Journal of Chemical Biology. 5: 989-92. PMID 15239057 DOI: 10.1002/Cbic.200400003 |
0.605 |
|
| 2004 |
Dürr C, Hoffmeister D, Wohlert SE, Ichinose K, Weber M, Von Mulert U, Thorson JS, Bechthold A. The glycosyltransferase UrdGT2 catalyzes both C- and O-glycosidic sugar transfers. Angewandte Chemie (International Ed. in English). 43: 2962-5. PMID 15170316 DOI: 10.1002/Anie.200453758 |
0.58 |
|
| 2004 |
Yang J, Hoffmeister D, Liu L, Fu X, Thorson JS. Natural product glycorandomization. Bioorganic & Medicinal Chemistry. 12: 1577-84. PMID 15112655 DOI: 10.1016/J.Bmc.2003.12.046 |
0.63 |
|
| 2004 |
Thorson JS, Barton WA, Hoffmeister D, Albermann C, Nikolov DB. Structure-based enzyme engineering and its impact on in vitro glycorandomization. Chembiochem : a European Journal of Chemical Biology. 5: 16-25. PMID 14695508 DOI: 10.1002/Cbic.200300620 |
0.778 |
|
| 2004 |
Dürr C, Hoffmeister D, Wohlert S, Ichinose K, Weber M, von Mulert U, Thorson JS, Bechthold A. Die Glycosyltransferase UrdGT2 katalysiert sowohl C- als auch O-glycosidischen Zuckertransfer Angewandte Chemie. 116: 3022-3025. DOI: 10.1002/Ange.200453758 |
0.553 |
|
| 2003 |
Hoffmeister D, Yang J, Liu L, Thorson JS. Creation of the first anomeric D/L-sugar kinase by means of directed evolution. Proceedings of the National Academy of Sciences of the United States of America. 100: 13184-9. PMID 14612558 DOI: 10.1073/Pnas.100.23.13184 |
0.656 |
|
| 2003 |
Fu X, Albermann C, Jiang J, Liao J, Zhang C, Thorson JS. Antibiotic optimization via in vitro glycorandomization. Nature Biotechnology. 21: 1467-9. PMID 14608364 DOI: 10.1038/Nbt909 |
0.777 |
|
| 2003 |
Liu W, Ahlert J, Gao Q, Wendt-Pienkowski E, Shen B, Thorson JS. Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model. Proceedings of the National Academy of Sciences of the United States of America. 100: 11959-63. PMID 14528002 DOI: 10.1073/Pnas.2034291100 |
0.565 |
|
| 2003 |
Biggins JB, Onwueme KC, Thorson JS. Resistance to enediyne antitumor antibiotics by CalC self-sacrifice. Science (New York, N.Y.). 301: 1537-41. PMID 12970566 DOI: 10.1126/Science.1086695 |
0.651 |
|
| 2003 |
Yang J, Fu X, Jia Q, Shen J, Biggins JB, Jiang J, Zhao J, Schmidt JJ, Wang PG, Thorson JS. Studies on the substrate specificity of Escherichia coli galactokinase. Organic Letters. 5: 2223-6. PMID 12816414 DOI: 10.1021/Ol034642D |
0.71 |
|
| 2003 |
Jiang J, Albermann C, Thorson JS. Application of the nucleotidylyltransferase Ep toward the chemoenzymatic synthesis of dTDP-desosamine analogues. Chembiochem : a European Journal of Chemical Biology. 4: 443-6. PMID 12740816 DOI: 10.1002/Cbic.200200566 |
0.684 |
|
| 2003 |
Albermann C, Soriano A, Jiang J, Vollmer H, Biggins JB, Barton WA, Lesniak J, Nikolov DB, Thorson JS. Substrate specificity of NovM: implications for novobiocin biosynthesis and glycorandomization. Organic Letters. 5: 933-6. PMID 12633109 DOI: 10.1021/Ol0341086 |
0.809 |
|
| 2003 |
Zazopoulos E, Huang K, Staffa A, Liu W, Bachmann BO, Nonaka K, Ahlert J, Thorson JS, Shen B, Farnet CM. A genomics-guided approach for discovering and expressing cryptic metabolic pathways. Nature Biotechnology. 21: 187-90. PMID 12536216 DOI: 10.1038/Nbt784 |
0.59 |
|
| 2002 |
Losey HC, Jiang J, Biggins JB, Oberthür M, Ye XY, Dong SD, Kahne D, Thorson JS, Walsh CT. Incorporation of glucose analogs by GtfE and GtfD from the vancomycin biosynthetic pathway to generate variant glycopeptides. Chemistry & Biology. 9: 1305-14. PMID 12498883 DOI: 10.1016/S1074-5521(02)00270-3 |
0.723 |
|
| 2002 |
Barton WA, Biggins JB, Jiang J, Thorson JS, Nikolov DB. Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering. Proceedings of the National Academy of Sciences of the United States of America. 99: 13397-402. PMID 12374866 DOI: 10.1073/Pnas.192468299 |
0.687 |
|
| 2002 |
Ahlert J, Shepard E, Lomovskaya N, Zazopoulos E, Staffa A, Bachmann BO, Huang K, Fonstein L, Czisny A, Whitwam RE, Farnet CM, Thorson JS. The calicheamicin gene cluster and its iterative type I enediyne PKS. Science (New York, N.Y.). 297: 1173-6. PMID 12183629 DOI: 10.1126/Science.1072105 |
0.77 |
|
| 2001 |
Jiang J, Biggins JB, Thorson JS. Expanding the Pyrimidine Diphosphosugar Repertoire: The Chemoenzymatic Synthesis of Amino- and Acetamidoglucopyranosyl Derivatives. Angewandte Chemie (International Ed. in English). 40: 1502-1505. PMID 29712364 DOI: 10.1002/1521-3773(20010417)40:8<1502::Aid-Anie1502>3.0.Co;2-K |
0.675 |
|
| 2001 |
Barton WA, Lesniak J, Biggins JB, Jeffrey PD, Jiang J, Rajashankar KR, Thorson JS, Nikolov DB. Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization. Nature Structural Biology. 8: 545-51. PMID 11373625 DOI: 10.1038/88618 |
0.733 |
|
| 2001 |
Jiang J, Biggins JB, Thorson JS. Expanding the Pyrimidine Diphosphosugar Repertoire: The Chemoenzymatic Synthesis of Amino- and Acetamidoglucopyranosyl Derivatives This contribution was supported by the National Institutes of Health (GM58196 and CA84374), a Cancer Center Support Grant (CA-08748), and a grant from the Special Projects Committee of the Society of Memorial Sloan-Kettering Cancer Center. J.S.T. is an Alfred P. Sloan Research Fellow and a Rita Allen Foundation Scholar. Angewandte Chemie (International Ed. in English). 40: 1502-1505. PMID 11317315 DOI: 10.1002/1521-3773(20010417)40:8<1502::AID-ANIE1502>3.0.CO;2-K |
0.605 |
|
| 2001 |
Thorson JS. Nature's carbohydrate chemists: The enzymatic glycosylation of bioactive bacterial metabolites Current Organic Chemistry. 5: 139-167. DOI: 10.2174/1385272013375706 |
0.385 |
|
| 2000 |
Thorson JS, Sievers EL, Ahlert J, Shepard E, Whitwam RE, Onwueme KC, Ruppen M. Understanding and exploiting nature's chemical arsenal: the past, present and future of calicheamicin research. Current Pharmaceutical Design. 6: 1841-79. PMID 11102565 DOI: 10.2174/1381612003398564 |
0.789 |
|
| 2000 |
Biggins JB, Prudent JR, Marshall DJ, Ruppen M, Thorson JS. A continuous assay for DNA cleavage: The application of 'break lights' to enediynes, iron-dependent and nucleases Proceedings of the National Academy of Sciences of the United States of America. 97: 13537-13542. PMID 11095715 DOI: 10.1073/Pnas.240460997 |
0.676 |
|
| 2000 |
Jiang J, Biggins JB, Thorson JS. A general enzymatic method for the synthesis of natural and 'unnatural' UDP- and TDP-nucleotide sugars [20] Journal of the American Chemical Society. 122: 6803-6804. DOI: 10.1021/Ja001444Y |
0.333 |
|
| 1999 |
Zhao Y, Thorson JS. Chemoenzymatic synthesis of the Salmonella group E1 core trisaccharide using a recombinant β-(1→4)-mannosyltransferase Carbohydrate Research. 319: 184-191. PMID 10520265 DOI: 10.1016/S0008-6215(99)00116-0 |
0.314 |
|
| 1999 |
Thorson JS, Shen B, Whitwam RE, Liu W, Li Y, Ahlert J. Enediyne biosynthesis and self-resistance: A progress report Bioorganic Chemistry. 27: 172-188. DOI: 10.1006/Bioo.1998.1122 |
0.594 |
|
| 1998 |
Zhao Y, Thorson JS. A Methodological Comparison: The Advantage of Phosphorimidates in Expanding the Sugar Nucleotide Repertoire. The Journal of Organic Chemistry. 63: 7568-7572. PMID 11672420 DOI: 10.1021/Jo981265N |
0.305 |
|
| 1998 |
Thorson JS, Cornish VW, Barrett JE, Cload ST, Yano T, Schultz PG. A biosynthetic approach for the incorporation of unnatural amino acids into proteins. Methods in Molecular Biology (Clifton, N.J.). 77: 43-73. PMID 9770661 DOI: 10.1385/0-89603-397-X:43 |
0.752 |
|
| 1998 |
Thorson JS, Shin I, Chapman E, Stenberg G, Mannervik B, Schultz PG. Analysis of the role of the active site tyrosine in human glutathione transferase A1-1 by unnatural amino acid mutagenesis Journal of the American Chemical Society. 120: 451-452. DOI: 10.1021/Ja9731682 |
0.589 |
|
| 1997 |
Chapman E, Thorson JS, Schultz PG. Mutational analysis of backbone hydrogen bonds in staphylococcal nuclease [2] Journal of the American Chemical Society. 119: 7151-7152. DOI: 10.1021/Ja970826+ |
0.377 |
|
| 1996 |
He X, Thorson JS, Liu HW. Probing the coenzyme and substrate binding events of CDP-D-glucose 4,6-dehydratase: mechanistic implications. Biochemistry. 35: 4721-31. PMID 8664262 DOI: 10.1021/Bi952706P |
0.333 |
|
| 1995 |
Thorson JS, Chapman E, Schultz PG. Analysis of hydrogen bonding strengths in proteins using unnatural amino acids Journal of the American Chemical Society. 117: 9361-9362. DOI: 10.1021/Ja00141A032 |
0.406 |
|
| 1995 |
Thorson JS, Chapman E, Murphy EC, Schultz PG, Judice JK. Linear Free Energy Analysis of Hydrogen Bonding in Proteins Journal of the American Chemical Society. 117: 1157-1158. DOI: 10.1021/Ja00108A044 |
0.382 |
|
| 1995 |
Liu H, Thorson JS, Miller VP, Kelley TM, Lei Y, Ploux O, He X, Yang D. Mechanistic Studies of the Biosynthesis of 3,6-Dideoxysugars in Bacteria: Exploration of a Novel C-O Bond Cleavage Event Journal of the Chinese Chemical Society. 42: 627-636. DOI: 10.1002/Jccs.199500085 |
0.312 |
|
| 1994 |
Lo SF, Miller VP, Lei Y, Thorson JS, Liu HW, Schottel JL. CDP-6-deoxy-delta 3,4-glucoseen reductase from Yersinia pseudotuberculosis: enzyme purification and characterization of the cloned gene. Journal of Bacteriology. 176: 460-8. PMID 8288541 DOI: 10.1128/Jb.176.2.460-468.1994 |
0.366 |
|
| 1994 |
Thorson JS, Kelly TM, Liu HW. Cloning, sequencing, and overexpression in Escherichia coli of the alpha-D-glucose-1-phosphate cytidylyltransferase gene isolated from Yersinia pseudotuberculosis. Journal of Bacteriology. 176: 1840-9. PMID 8144449 DOI: 10.1128/Jb.176.7.1840-1849.1994 |
0.364 |
|
| 1994 |
Thorson JS, Lo SF, Ploux O, He X, Liu HW. Studies of the biosynthesis of 3,6-dideoxyhexoses: molecular cloning and characterization of the asc (ascarylose) region from Yersinia pseudotuberculosis serogroup VA. Journal of Bacteriology. 176: 5483-93. PMID 8071227 DOI: 10.1128/Jb.176.17.5483-5493.1994 |
0.327 |
|
| 1994 |
Liu HW, Thorson JS. Pathways and mechanisms in the biogenesis of novel deoxysugars by bacteria. Annual Review of Microbiology. 48: 223-56. PMID 7826006 DOI: 10.1146/Annurev.Mi.48.100194.001255 |
0.353 |
|
| 1992 |
Thorson JS, Oh E, Liu HW. Studies of complex enzymic pyridine nucleotide-dependent transformations: structure and cofactor binding correlation in CDP-D-glucose oxidoreductase Journal of the American Chemical Society. 114: 6941-6942. DOI: 10.1021/Ja00043A064 |
0.323 |
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