Jin-Soo Kim - Publications

Affiliations: 
1994 Department of Biochemistry University of Wisconsin, Madison, Madison, WI 

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lee J, Lim K, Kim A, Mok YG, Chung E, Cho SI, Lee JM, Kim JS. Prime editing with genuine Cas9 nickases minimizes unwanted indels. Nature Communications. 14: 1786. PMID 36997524 DOI: 10.1038/s41467-023-37507-8  0.3
2023 Kim YH, Kim N, Okafor I, Choi S, Min S, Lee J, Bae SM, Choi K, Choi J, Harihar V, Kim Y, Kim JS, Kleinstiver BP, Lee JK, Ha T, et al. Sniper2L is a high-fidelity Cas9 variant with high activity. Nature Chemical Biology. PMID 36894722 DOI: 10.1038/s41589-023-01279-5  0.304
2020 Kim D, Lim K, Kim DE, Kim JS. Genome-wide specificity of dCpf1 cytidine base editors. Nature Communications. 11: 4072. PMID 32792663 DOI: 10.1038/S41467-020-17889-9  0.338
2019 Kim D, Luk K, Wolfe SA, Kim JS. Evaluating and Enhancing Target Specificity of Gene-Editing Nucleases and Deaminases. Annual Review of Biochemistry. PMID 30883196 DOI: 10.1146/Annurev-Biochem-013118-111730  0.362
2019 Kim D, Kim DE, Lee G, Cho SI, Kim JS. Genome-wide target specificity of CRISPR RNA-guided adenine base editors. Nature Biotechnology. PMID 30833658 DOI: 10.1038/S41587-019-0050-1  0.37
2018 Kim D, Kim JS. DIG-seq: a genome-wide CRISPR off-target profiling method using chromatin DNA. Genome Research. PMID 30413470 DOI: 10.1101/Gr.236620.118  0.33
2018 Lee JK, Jeong E, Lee J, Jung M, Shin E, Kim YH, Lee K, Jung I, Kim D, Kim S, Kim JS. Directed evolution of CRISPR-Cas9 to increase its specificity. Nature Communications. 9: 3048. PMID 30082838 DOI: 10.1038/S41467-018-05477-X  0.361
2018 Jeon Y, Choi YH, Jang Y, Yu J, Goo J, Lee G, Jeong YK, Lee SH, Kim IS, Kim JS, Jeong C, Lee S, Bae S. Direct observation of DNA target searching and cleavage by CRISPR-Cas12a. Nature Communications. 9: 2777. PMID 30018371 DOI: 10.1038/S41467-018-05245-X  0.311
2017 Kweon J, Jang AH, Kim DE, Yang JW, Yoon M, Rim Shin H, Kim JS, Kim Y. Fusion guide RNAs for orthogonal gene manipulation with Cas9 and Cpf1. Nature Communications. 8: 1723. PMID 29167440 DOI: 10.1038/S41467-017-01650-W  0.317
2017 Kim S, Bae T, Hwang J, Kim JS. Rescue of high-specificity Cas9 variants using sgRNAs with matched 5' nucleotides. Genome Biology. 18: 218. PMID 29141659 DOI: 10.1186/S13059-017-1355-3  0.353
2017 Fogarty NME, McCarthy A, Snijders KE, Powell BE, Kubikova N, Blakeley P, Lea R, Elder K, Wamaitha SE, Kim D, Maciulyte V, Kleinjung J, Kim JS, Wells D, Vallier L, et al. Genome editing reveals a role for OCT4 in human embryogenesis. Nature. PMID 28953884 DOI: 10.1038/Nature24033  0.326
2017 Kim HS, Lee K, Bae S, Park J, Lee CK, Kim M, Kim E, Kim M, Kim S, Kim C, Kim JS. CRISPR/Cas9-mediated Gene-knockout Screens and Target Identification via Whole Genome Sequencing Uncover Host Genes Required for Picornavirus Infection. The Journal of Biological Chemistry. PMID 28446605 DOI: 10.1074/Jbc.M117.782425  0.339
2017 Kim SJ, Habib O, Kim JS, Han HW, Koo SK, Kim JH. A homozygous Keap1-knockout human embryonic stem cell line generated using CRISPR/Cas9 mediates gene targeting. Stem Cell Research. 19: 52-54. PMID 28413007 DOI: 10.1016/J.Scr.2016.12.028  0.313
2017 Kim D, Lim K, Kim ST, Yoon SH, Kim K, Ryu SM, Kim JS. Genome-wide target specificities of CRISPR RNA-guided programmable deaminases. Nature Biotechnology. PMID 28398345 DOI: 10.1038/Nbt.3852  0.343
2017 Kim H, Kim ST, Ryu J, Kang BC, Kim JS, Kim SG. CRISPR/Cpf1-mediated DNA-free plant genome editing. Nature Communications. 8: 14406. PMID 28205546 DOI: 10.1038/Ncomms14406  0.347
2016 Malnoy M, Viola R, Jung MH, Koo OJ, Kim S, Kim JS, Velasco R, Nagamangala Kanchiswamy C. DNA-Free Genetically Edited Grapevine and Apple Protoplast Using CRISPR/Cas9 Ribonucleoproteins. Frontiers in Plant Science. 7: 1904. PMID 28066464 DOI: 10.3389/Fpls.2016.01904  0.333
2016 Thomas SP, Kim E, Kim JS, Raines RT. Knockout of the Ribonuclease Inhibitor Gene Leaves Human Cells Vulnerable to Secretory Ribonucleases. Biochemistry. PMID 27806571 DOI: 10.1021/Acs.Biochem.6B01003  0.504
2016 Lim Y, Bak SY, Sung K, Jeong E, Lee SH, Kim JS, Bae S, Kim SK. Structural roles of guide RNAs in the nuclease activity of Cas9 endonuclease. Nature Communications. 7: 13350. PMID 27804953 DOI: 10.1038/Ncomms13350  0.316
2016 Kim JS. Genome editing comes of age. Nature Protocols. 11: 1573-1578. PMID 27490630 DOI: 10.1038/Nprot.2016.104  0.324
2016 Shin SE, Lim JM, Koh HG, Kim EK, Kang NK, Jeon S, Kwon S, Shin WS, Lee B, Hwangbo K, Kim J, Ye SH, Yun JY, Seo H, Oh HM, ... ... Kim JS, et al. CRISPR/Cas9-induced knockout and knock-in mutations in Chlamydomonas reinhardtii. Scientific Reports. 6: 27810. PMID 27291619 DOI: 10.1038/Srep27810  0.321
2016 Kim D, Kim J, Hur JK, Been KW, Yoon SH, Kim JS. Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells. Nature Biotechnology. PMID 27272384 DOI: 10.1038/Nbt.3609  0.354
2016 Kim H, Kim ST, Ryu J, Choi MK, Kweon J, Kang BC, Ahn HM, Bae S, Kim JS, Kim SG. A simple, flexible and high-throughput cloning system for plant genome editing via CRISPR-Cas system. Journal of Integrative Plant Biology. PMID 26946469 DOI: 10.1111/Jipb.12474  0.347
2016 Kim D, Kim S, Kim S, Park J, Kim JS. Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq. Genome Research. PMID 26786045 DOI: 10.1101/Gr.199588.115  0.338
2015 Witte H, Moreno E, Rödelsperger C, Kim J, Kim JS, Streit A, Sommer RJ. Gene inactivation using the CRISPR/Cas9 system in the nematode Pristionchus pacificus. Development Genes and Evolution. 225: 55-62. PMID 25548084 DOI: 10.1007/S00427-014-0486-8  0.317
2014 Song M, Kim YH, Kim JS, Kim H. Genome engineering in human cells. Methods in Enzymology. 546: 93-118. PMID 25398337 DOI: 10.1016/B978-0-12-801185-0.00005-2  0.348
2014 Park TS, Lee HJ, Kim KH, Kim JS, Han JY. Targeted gene knockout in chickens mediated by TALENs. Proceedings of the National Academy of Sciences of the United States of America. 111: 12716-21. PMID 25139993 DOI: 10.1073/Pnas.1410555111  0.337
2014 Koo OJ, Park SJ, Lee C, Kang JT, Kim S, Moon JH, Choi JY, Kim H, Jang G, Kim JS, Kim S, Lee BC. Production of Mutated Porcine Embryos Using Zinc Finger Nucleases and a Reporter-based Cell Enrichment System. Asian-Australasian Journal of Animal Sciences. 27: 324-9. PMID 25049958 DOI: 10.5713/Ajas.2013.13481  0.314
2014 Lee JS, Kwak SJ, Kim J, Kim AK, Noh HM, Kim JS, Yu K. RNA-guided genome editing in Drosophila with the purified Cas9 protein. G3 (Bethesda, Md.). 4: 1291-5. PMID 24875628 DOI: 10.1534/G3.114.012179  0.323
2014 Moon J, Lee C, Kim SJ, Choi JY, Lee BC, Kim JS, Jang G. Production of CMAH Knockout Preimplantation Embryos Derived From Immortalized Porcine Cells Via TALE Nucleases. Molecular Therapy. Nucleic Acids. 3: e166. PMID 24866481 DOI: 10.1038/Mtna.2014.15  0.314
2014 Kim YH, Ramakrishna S, Kim H, Kim JS. Enrichment of cells with TALEN-induced mutations using surrogate reporters. Methods (San Diego, Calif.). 69: 108-17. PMID 24780521 DOI: 10.1016/J.Ymeth.2014.04.012  0.336
2014 Kim S, Kim D, Cho SW, Kim J, Kim JS. Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins. Genome Research. 24: 1012-9. PMID 24696461 DOI: 10.1101/Gr.171322.113  0.365
2014 Kim H, Kim JS. A guide to genome engineering with programmable nucleases. Nature Reviews. Genetics. 15: 321-34. PMID 24690881 DOI: 10.1038/Nrg3686  0.36
2014 Ramakrishna S, Cho SW, Kim S, Song M, Gopalappa R, Kim JS, Kim H. Surrogate reporter-based enrichment of cells containing RNA-guided Cas9 nuclease-induced mutations. Nature Communications. 5: 3378. PMID 24569644 DOI: 10.1038/Ncomms4378  0.317
2014 Bae S, Park J, Kim JS. Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases. Bioinformatics (Oxford, England). 30: 1473-5. PMID 24463181 DOI: 10.1093/Bioinformatics/Btu048  0.305
2014 Kim JM, Kim D, Kim S, Kim JS. Genotyping with CRISPR-Cas-derived RNA-guided endonucleases. Nature Communications. 5: 3157. PMID 24445736 DOI: 10.1038/Ncomms4157  0.317
2014 Cho SW, Kim S, Kim Y, Kweon J, Kim HS, Bae S, Kim JS. Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases. Genome Research. 24: 132-41. PMID 24253446 DOI: 10.1101/Gr.162339.113  0.355
2013 Kim H, Kim MS, Wee G, Lee CI, Kim H, Kim JS. Magnetic separation and antibiotics selection enable enrichment of cells with ZFN/TALEN-induced mutations. Plos One. 8: e56476. PMID 23441197 DOI: 10.1371/Journal.Pone.0056476  0.317
2013 Cho SW, Kim S, Kim JM, Kim JS. Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease. Nature Biotechnology. 31: 230-2. PMID 23360966 DOI: 10.1038/Nbt.2507  0.329
2012 Kim E, Kim S, Kim DH, Choi BS, Choi IY, Kim JS. Precision genome engineering with programmable DNA-nicking enzymes. Genome Research. 22: 1327-33. PMID 22522391 DOI: 10.1101/Gr.138792.112  0.326
2012 Lee HJ, Kweon J, Kim E, Kim S, Kim JS. Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleases. Genome Research. 22: 539-48. PMID 22183967 DOI: 10.1101/Gr.129635.111  0.321
2011 Kim H, Um E, Cho SR, Jung C, Kim H, Kim JS. Surrogate reporters for enrichment of cells with nuclease-induced mutations. Nature Methods. 8: 941-3. PMID 21983922 DOI: 10.1038/Nmeth.1733  0.322
2010 Lee HJ, Kim E, Kim J. Targeted chromosomal deletions in human cells using zinc finger nucleases Genome Research. 20: 81-89. PMID 19952142 DOI: 10.1101/Gr.099747.109  0.336
2009 Kim HJ, Lee HJ, Kim H, Cho SW, Kim JS. Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly. Genome Research. 19: 1279-88. PMID 19470664 DOI: 10.1101/Gr.089417.108  0.349
2008 Yun CO, Shin HC, Kim TD, Yoon WH, Kang YA, Kwon HS, Kim SK, Kim JS. Transduction of artificial transcriptional regulatory proteins into human cells. Nucleic Acids Research. 36: e103. PMID 18644841 DOI: 10.1093/Nar/Gkn398  0.355
2005 Park K, Jang Y, Lee H, Kim J. Phenotypic Alteration and Target Gene Identification Using Combinatorial Libraries of Zinc Finger Proteins in Prokaryotic Cells Journal of Bacteriology. 187: 5496-5499. PMID 16030245 DOI: 10.1128/Jb.187.15.5496-5499.2005  0.354
2005 Park KS, Seol W, Yang HY, Lee SI, Kim SK, Kwon RJ, Kim EJ, Roh YH, Seong BL, Kim JS. Identification and use of zinc finger transcription factors that increase production of recombinant proteins in yeast and mammalian cells. Biotechnology Progress. 21: 664-70. PMID 15932240 DOI: 10.1021/Bp049658X  0.355
2004 Lee D, Kim YH, Kim J, Seol W. Induction and characterization of taxol-resistance phenotypes with a transiently expressed artificial transcriptional activator library. Nucleic Acids Research. 32. PMID 15304545 DOI: 10.1093/Nar/Gnh114  0.322
2003 Lee DK, Park JW, Kim YJ, Kim J, Lee Y, Kim J, Kim JS. Toward a functional annotation of the human genome using artificial transcription factors. Genome Research. 13: 2708-16. PMID 14656973 DOI: 10.1101/Gr.1397903  0.308
2003 Park K, Lee D, Lee H, Lee Y, Jang Y, Kim YH, Yang H, Lee S, Seol W, Kim J. Phenotypic alteration of eukaryotic cells using randomized libraries of artificial transcription factors. Nature Biotechnology. 21: 1208-1214. PMID 12960965 DOI: 10.1038/Nbt868  0.347
2003 Bae KH, Kwon YD, Shin HC, Hwang MS, Ryu EH, Park KS, Yang HY, Lee DK, Lee Y, Park J, Kwon HS, Kim HW, Yeh BI, Lee HW, Sohn SH, ... ... Kim JS, et al. Human zinc fingers as building blocks in the construction of artificial transcription factors. Nature Biotechnology. 21: 275-80. PMID 12592413 DOI: 10.1038/Nbt796  0.348
2003 Lee D, Seol W, Kim J. Custom DNA-Binding Proteins and Artificial Transcription Factors Current Topics in Medicinal Chemistry. 3: 645-657. PMID 12570857 DOI: 10.2174/1568026033452384  0.315
2000 Kang JS, Kim JS. Zinc finger proteins as designer transcription factors Journal of Biological Chemistry. 275: 8742-8748. PMID 10722717 DOI: 10.1074/Jbc.275.12.8742  0.364
1998 Kim JS, Pabo CO. Getting a handhold on DNA: design of poly-zinc finger proteins with femtomolar dissociation constants. Proceedings of the National Academy of Sciences of the United States of America. 95: 2812-7. PMID 9501172 DOI: 10.1073/Pnas.95.6.2812  0.616
1997 Matoušek J, Kim JS, Souček J, Rìha J, Ribó M, Leland PA, Raines RT. Ribonucleases endowed with specific toxicity for spermatogenic layers. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 118: 881-888. PMID 21399757 DOI: 10.1016/S0305-0491(97)00278-2  0.724
1997 Kim JS, Pabo CO. Transcriptional repression by zinc finger peptides. Exploring the potential for applications in gene therapy. The Journal of Biological Chemistry. 272: 29795-800. PMID 9368051 DOI: 10.1074/Jbc.272.47.29795  0.61
1997 Kim JS, Kim J, Cepek KL, Sharp PA, Pabo CO. Design of TATA box-binding protein/zinc finger fusions for targeted regulation of gene expression. Proceedings of the National Academy of Sciences of the United States of America. 94: 3616-20. PMID 9108026 DOI: 10.1073/Pnas.94.8.3616  0.631
1995 Kim JS, Soucek J, Matousek J, Raines RT. Mechanism of ribonuclease cytotoxicity. The Journal of Biological Chemistry. 270: 31097-102. PMID 8537370 DOI: 10.1074/Jbc.270.52.31097  0.478
1995 Kim JS, Raines RT. Dibromobimane as a fluorescent crosslinking reagent. Analytical Biochemistry. 225: 174-6. PMID 7778775 DOI: 10.1006/Abio.1995.1131  0.403
1995 Kim JS, Soucek J, Matousek J, Raines RT. Catalytic activity of bovine seminal ribonuclease is essential for its immunosuppressive and other biological activities. The Biochemical Journal. 308: 547-50. PMID 7772040 DOI: 10.1042/Bj3080547  0.478
1995 Kim JS, Soucek J, Matousek J, Raines RT. Structural basis for the biological activities of bovine seminal ribonuclease. The Journal of Biological Chemistry. 270: 10525-30. PMID 7737987 DOI: 10.1074/Jbc.270.18.10525  0.43
1994 Kim JS, Raines RT. A misfolded but active dimer of bovine seminal ribonuclease. European Journal of Biochemistry / Febs. 224: 109-14. PMID 8076630 DOI: 10.1111/J.1432-1033.1994.Tb20001.X  0.464
1994 Kim JS, Raines RT. Peptide tags for a dual affinity fusion system. Analytical Biochemistry. 219: 165-6. PMID 8059949 DOI: 10.1006/Abio.1994.1251  0.49
1993 Kim JS, Raines RT. Ribonuclease S-peptide as a carrier in fusion proteins. Protein Science : a Publication of the Protein Society. 2: 348-56. PMID 8453373 DOI: 10.1002/Pro.5560020307  0.479
1993 Kim JS, Raines RT. Bovine seminal ribonuclease produced from a synthetic gene. The Journal of Biological Chemistry. 268: 17392-6. PMID 7688724  0.44
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