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Hongxing Lei, Ph.D. - Publications

Affiliations: 
2003 Kansas State University, Manhattan, KS, United States 
Area:
Biochemistry
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34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Song F, Qian Y, Peng X, Han G, Wang J, Bai Z, Crack PJ, Lei H. Perturbation of the transcriptome: implications of the innate immune system in Alzheimer's disease. Current Opinion in Pharmacology. 26: 47-53. PMID 26480202 DOI: 10.1016/J.Coph.2015.09.015  0.319
2015 Song F, Han G, Bai Z, Peng X, Wang J, Lei H. Alzheimer's Disease: Genomics and Beyond. International Review of Neurobiology. 121: 1-24. PMID 26315760 DOI: 10.1016/Bs.Irn.2015.05.001  0.328
2015 Luo H, Han G, Wang J, Zeng F, Li Y, Shao S, Song F, Bai Z, Peng X, Wang YJ, Shi X, Lei H. Common Aging Signature in the Peripheral Blood of Vascular Dementia and Alzheimer's Disease. Molecular Neurobiology. PMID 26099307 DOI: 10.1007/S12035-015-9288-X  0.319
2014 Bai Z, Han G, Xie B, Wang J, Song F, Peng X, Lei H. AlzBase: an Integrative Database for Gene Dysregulation in Alzheimer's Disease. Molecular Neurobiology. PMID 25432889 DOI: 10.1007/S12035-014-9011-3  0.328
2014 Feng X, Bai Z, Wang J, Xie B, Sun J, Han G, Song F, Crack PJ, Duan Y, Lei H. Robust gene dysregulation in Alzheimer's disease brains. Journal of Alzheimer's Disease : Jad. 41: 587-97. PMID 24662101 DOI: 10.3233/Jad-140147  0.32
2014 Lei H, Sun J, Baldwin EP, Segal DJ, Duan Y. Conformational elasticity can facilitate TALE-DNA recognition. Advances in Protein Chemistry and Structural Biology. 94: 347-64. PMID 24629191 DOI: 10.1016/B978-0-12-800168-4.00009-3  0.34
2014 Wang J, Feng X, Bai Z, Jin LW, Duan Y, Lei H. Chromosome 19p in Alzheimer's disease: when genome meets transcriptome. Journal of Alzheimer's Disease : Jad. 38: 245-50. PMID 23963291 DOI: 10.3233/Jad-130917  0.304
2013 Han G, Wang J, Zeng F, Feng X, Yu J, Cao HY, Yi X, Zhou H, Jin LW, Duan Y, Wang YJ, Lei H. Characteristic transformation of blood transcriptome in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 35: 373-86. PMID 23411692 DOI: 10.3233/Jad-121963  0.318
2012 Liang D, Han G, Feng X, Sun J, Duan Y, Lei H. Concerted perturbation observed in a hub network in Alzheimer's disease. Plos One. 7: e40498. PMID 22815752 DOI: 10.1371/Journal.Pone.0040498  0.333
2012 Sun J, Feng X, Liang D, Duan Y, Lei H. Down-regulation of energy metabolism in Alzheimer's disease is a protective response of neurons to the microenvironment. Journal of Alzheimer's Disease : Jad. 28: 389-402. PMID 22008267 DOI: 10.3233/Jad-2011-111313  0.312
2012 Sun J, Feng X, Liang D, Duan Y, Lei H. Dynamic neuronal regulatory network during the progression of Alzheimer’s disease suggests an adaptive survival strategy Molecular Neurodegeneration. 7: 1-1. DOI: 10.1186/1750-1326-7-S1-O3  0.326
2011 Lei H, Chen C, Xiao Y, Duan Y. The protein folding network indicates that the ultrafast folding mutant of villin headpiece subdomain has a deeper folding funnel. The Journal of Chemical Physics. 134: 205104. PMID 21639484 DOI: 10.1063/1.3596272  0.329
2010 Lei H, Su Y, Jin L, Duan Y. Folding network of villin headpiece subdomain. Biophysical Journal. 99: 3374-84. PMID 21081086 DOI: 10.1016/J.Bpj.2010.08.081  0.311
2009 Lei H, Wang ZX, Wu C, Duan Y. Dual folding pathways of an alpha/beta protein from all-atom ab initio folding simulations. The Journal of Chemical Physics. 131: 165105. PMID 19894980 DOI: 10.1063/1.3238567  0.338
2008 Lei H, Deng X, Wang Z, Duan Y. The fast-folding HP35 double mutant has a substantially reduced primary folding free energy barrier. The Journal of Chemical Physics. 129: 155104. PMID 19045234 DOI: 10.1063/1.2995987  0.342
2008 Wu C, Wang Z, Lei H, Duan Y, Bowers MT, Shea JE. The binding of thioflavin T and its neutral analog BTA-1 to protofibrils of the Alzheimer's disease Abeta(16-22) peptide probed by molecular dynamics simulations. Journal of Molecular Biology. 384: 718-29. PMID 18851978 DOI: 10.1016/J.Jmb.2008.09.062  0.332
2008 Lei H, Wu C, Wang ZX, Zhou Y, Duan Y. Folding processes of the B domain of protein A to the native state observed in all-atom ab initio folding simulations. The Journal of Chemical Physics. 128: 235105. PMID 18570534 DOI: 10.1063/1.2937135  0.37
2008 Lei H, Duan Y. Protein folding and unfolding by all-atom molecular dynamics simulations. Methods in Molecular Biology (Clifton, N.J.). 443: 277-95. PMID 18446293 DOI: 10.1007/978-1-59745-177-2_15  0.319
2008 Liu H, Dastidar SG, Lei H, Zhang W, Lee MC, Duan Y. Conformational changes in protein function. Methods in Molecular Biology (Clifton, N.J.). 443: 258-75. PMID 18446292 DOI: 10.1007/978-1-59745-177-2_14  0.314
2007 Lei H, Duan Y. Two-stage folding of HP-35 from ab initio simulations. Journal of Molecular Biology. 370: 196-206. PMID 17512537 DOI: 10.1016/J.Jmb.2007.04.040  0.357
2007 Lei H, Wu C, Liu H, Duan Y. Folding free-energy landscape of villin headpiece subdomain from molecular dynamics simulations. Proceedings of the National Academy of Sciences of the United States of America. 104: 4925-30. PMID 17360390 DOI: 10.1073/Pnas.0608432104  0.349
2007 Wu C, Wang Z, Lei H, Zhang W, Duan Y. Dual binding modes of Congo red to amyloid protofibril surface observed in molecular dynamics simulations. Journal of the American Chemical Society. 129: 1225-32. PMID 17263405 DOI: 10.1021/Ja0662772  0.312
2006 Lei H, Dastidar SG, Duan Y. Folding transition-state and denatured-state ensembles of FSD-1 from folding and unfolding simulations. The Journal of Physical Chemistry. B. 110: 22001-8. PMID 17064170 DOI: 10.1021/Jp063716A  0.352
2006 Wu C, Lei H, Wang Z, Zhang W, Duan Y. Phenol red interacts with the protofibril-like oligomers of an amyloidogenic hexapeptide NFGAIL through both hydrophobic and aromatic contacts. Biophysical Journal. 91: 3664-72. PMID 16935948 DOI: 10.1529/Biophysj.106.081877  0.334
2006 Wang ZX, Zhang W, Wu C, Lei H, Cieplak P, Duan Y. Strike a balance: optimization of backbone torsion parameters of AMBER polarizable force field for simulations of proteins and peptides. Journal of Computational Chemistry. 27: 781-90. PMID 16526038 DOI: 10.1002/Jcc.20386  0.307
2006 Lei H, Wu C, Wang Z, Duan Y. Molecular dynamics simulations and free energy analyses on the dimer formation of an amyloidogenic heptapeptide from human beta2-microglobulin: implication for the protofibril structure. Journal of Molecular Biology. 356: 1049-63. PMID 16403526 DOI: 10.1016/J.Jmb.2005.11.087  0.354
2005 Chowdhury S, Lei H, Duan Y. Denatured-state ensemble and the early-stage folding of the G29A mutant of the B-domain of protein A. The Journal of Physical Chemistry. B. 109: 9073-81. PMID 16852080 DOI: 10.1021/Jp0449814  0.345
2005 Wu C, Lei H, Duan Y. Elongation of ordered peptide aggregate of an amyloidogenic hexapeptide NFGAIL observed in molecular dynamics simulations with explicit solvent. Journal of the American Chemical Society. 127: 13530-7. PMID 16190716 DOI: 10.1021/Ja050767X  0.332
2005 Wu C, Lei H, Duan Y. The role of Phe in the formation of well-ordered oligomers of amyloidogenic hexapeptide (NFGAIL) observed in molecular dynamics simulations with explicit solvent. Biophysical Journal. 88: 2897-906. PMID 15653723 DOI: 10.1529/Biophysj.104.055574  0.336
2004 Lei H, Duan Y. The role of plastic beta-hairpin and weak hydrophobic core in the stability and unfolding of a full sequence design protein. The Journal of Chemical Physics. 121: 12104-11. PMID 15634176 DOI: 10.1063/1.1822916  0.33
2004 Wu C, Lei H, Duan Y. Formation of partially ordered oligomers of amyloidogenic hexapeptide (NFGAIL) in aqueous solution observed in molecular dynamics simulations. Biophysical Journal. 87: 3000-9. PMID 15326028 DOI: 10.1529/Biophysj.104.047076  0.335
2004 Zhang W, Lei H, Chowdhury S, Duan Y. Fs-21 Peptides Can Form Both Single Helix and Helix−Turn−Helix The Journal of Physical Chemistry B. 108: 7479-7489. DOI: 10.1021/Jp037688X  0.326
2003 Lei H, Smith PE. The role of the unfolded state in hairpin stability. Biophysical Journal. 85: 3513-20. PMID 14645046 DOI: 10.1016/S0006-3495(03)74771-7  0.455
2003 Lei H, Smith PE. The Effects of Internal Water Molecules on the Structure and Dynamics of Chymotrypsin Inhibitor 2 The Journal of Physical Chemistry B. 107: 1395-1402. DOI: 10.1021/Jp0223105  0.445
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