Richard J. Perrin, M.D., Ph.D. - Publications

Affiliations: 
Neuropathology Washington University, Saint Louis, St. Louis, MO 

117 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Joseph-Mathurin N, Feldman RL, Lu R, Shirzadi Z, Toomer C, Saint Clair JR, Ma Y, McKay NS, Strain JF, Kilgore C, Friedrichsen KA, Chen CD, Gordon BA, Chen G, Hornbeck RC, ... ... Perrin RJ, et al. Presenilin-1 mutation position influences amyloidosis, small vessel disease, and dementia with disease stage. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38380882 DOI: 10.1002/alz.13729  0.357
2024 Wang Q, Schindler SE, Chen G, Mckay NS, McCullough A, Flores S, Liu J, Sun Z, Wang S, Wang W, Hassenstab J, Cruchaga C, Perrin RJ, Fagan AM, Morris JC, et al. Investigating White Matter Neuroinflammation in Alzheimer Disease Using Diffusion-Based Neuroinflammation Imaging. Neurology. 102: e208013. PMID 38315956 DOI: 10.1212/WNL.0000000000208013  0.401
2024 Shen Y, Ali M, Timsina J, Wang C, Do A, Western D, Liu M, Gorijala P, Budde J, Liu H, Gordon B, McDade E, Morris JC, Llibre-Guerra JJ, Bateman RJ, ... ... Perrin RJ, et al. Systematic proteomics in Autosomal dominant Alzheimer's disease reveals decades-early changes of CSF proteins in neuronal death, and immune pathways. Medrxiv : the Preprint Server For Health Sciences. PMID 38260583 DOI: 10.1101/2024.01.12.24301242  0.412
2023 Millar PR, Gordon BA, Wisch JK, Schultz SA, Benzinger TL, Cruchaga C, Hassenstab JJ, Ibanez L, Karch C, Llibre-Guerra JJ, Morris JC, Perrin RJ, Supnet-Bell C, Xiong C, Allegri RF, et al. Advanced structural brain aging in preclinical autosomal dominant Alzheimer disease. Molecular Neurodegeneration. 18: 98. PMID 38111006 DOI: 10.1186/s13024-023-00688-3  0.543
2023 Tu JC, Millar PR, Strain JF, Eck A, Adeyemo B, Daniels A, Karch C, Huey ED, McDade E, Day GS, Yakushev I, Hassenstab J, Morris J, Llibre-Guerra JJ, Ibanez L, ... ... Perrin RJ, et al. Increasing hub disruption parallels dementia severity in autosomal dominant Alzheimer disease. Biorxiv : the Preprint Server For Biology. PMID 37961586 DOI: 10.1101/2023.10.29.564633  0.361
2023 Llibre-Guerra JJ, Iaccarino L, Coble D, Edwards L, Li Y, McDade E, Strom A, Gordon B, Mundada N, Schindler SE, Tsoy E, Ma Y, Lu R, Fagan AM, Benzinger TLS, ... ... Perrin RJ, et al. Longitudinal clinical, cognitive and biomarker profiles in dominantly inherited versus sporadic early-onset Alzheimer's disease. Brain Communications. 5: fcad280. PMID 37942088 DOI: 10.1093/braincomms/fcad280  0.63
2023 Rahmani F, Brier MR, Gordon BA, McKay N, Flores S, Keefe S, Hornbeck R, Ances B, Joseph-Mathurin N, Xiong C, Wang G, Raji CA, Libre-Guerra JJ, Perrin RJ, McDade E, et al. T1 and FLAIR signal intensities are related to tau pathology in dominantly inherited Alzheimer disease. Human Brain Mapping. PMID 37867465 DOI: 10.1002/hbm.26514  0.536
2023 Gorijala P, Aslam MM, Dang LT, Xicota L, Fernandez MV, Sung YJ, Fan KH, Feingold E, Surace EI, Chhatwal JP, Hom CL, Hartley SL, Hassenstab J, Perrin RJ, Mapstone M, et al. Alzheimer's polygenic risk scores are associated with cognitive phenotypes in Down syndrome. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37855447 DOI: 10.1002/alz.13506  0.398
2023 Shirzadi Z, Schultz SA, Yau WW, Joseph-Mathurin N, Fitzpatrick CD, Levin R, Kantarci K, Preboske GM, Jack CR, Farlow MR, Hassenstab J, Jucker M, Morris JC, Xiong C, Karch CM, ... ... Perrin RJ, et al. Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease. Jama Neurology. PMID 37843849 DOI: 10.1001/jamaneurol.2023.3618  0.593
2023 Wagemann O, Li Y, Hassenstab J, Aschenbrenner AJ, McKay NS, Gordon BA, Benzinger TLS, Xiong C, Cruchaga C, Renton AE, Perrin RJ, Berman SB, Chhatwal JP, Farlow MR, Day GS, et al. Investigation of sex differences in mutation carriers of the Dominantly Inherited Alzheimer Network. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37740921 DOI: 10.1002/alz.13460  0.593
2023 Veitch DP, Weiner MW, Miller M, Aisen PS, Ashford MA, Beckett LA, Green RC, Harvey D, Jack CR, Jagust W, Landau SM, Morris JC, Nho KT, Nosheny R, Okonkwo O, ... Perrin RJ, et al. The Alzheimer's Disease Neuroimaging Initiative in the era of Alzheimer's disease treatment: A review of ADNI studies from 2021 to 2022. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37698424 DOI: 10.1002/alz.13449  0.449
2023 Tosun D, Yardibi O, Benzinger TLS, Kukull WA, Masters CL, Perrin RJ, Weiner MW, Simen A, Schwarz AJ. Identifying individuals with non-Alzheimer's disease co-pathologies: A precision medicine approach to clinical trials in sporadic Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37667412 DOI: 10.1002/alz.13447  0.456
2023 Johnson ECB, Bian S, Haque RU, Carter EK, Watson CM, Gordon BA, Ping L, Duong DM, Epstein MP, McDade E, Barthélemy NR, Karch CM, Xiong C, Cruchaga C, Perrin RJ, et al. Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease. Nature Medicine. PMID 37550416 DOI: 10.1038/s41591-023-02476-4  0.629
2023 McKay NS, Gordon BA, Hornbeck RC, Dincer A, Flores S, Keefe SJ, Joseph-Mathurin N, Jack CR, Koeppe R, Millar PR, Ances BM, Chen CD, Daniels A, Hobbs DA, Jackson K, ... ... Perrin RJ, et al. Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN). Nature Neuroscience. PMID 37429916 DOI: 10.1038/s41593-023-01359-8  0.581
2023 Sung YJ, Yang C, Norton J, Johnson M, Fagan A, Bateman RJ, Perrin RJ, Morris JC, Farlow MR, Chhatwal JP, Schofield PR, Chui H, Wang F, Novotny B, Eteleeb A, et al. Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer's disease. Science Translational Medicine. 15: eabq5923. PMID 37406134 DOI: 10.1126/scitranslmed.abq5923  0.605
2023 Cruchaga C, Western D, Timsina J, Wang L, Wang C, Yang C, Ali M, Beric A, Gorijala P, Kohlfeld P, Budde J, Levey A, Morris J, Perrin R, Ruiz A, et al. Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and informs causal proteins for Alzheimer's disease. Research Square. PMID 37333337 DOI: 10.21203/rs.3.rs-2814616/v1  0.368
2023 Schultz SA, Shirzadi Z, Schultz AP, Liu L, Fitzpatrick CD, McDade E, Barthelemy NR, Renton A, Esposito B, Joseph-Mathurin N, Cruchaga C, Chen CD, Goate A, Allegri RF, Benzinger TLS, ... ... Perrin RJ, et al. Location of pathogenic variants in PSEN1 impacts progression of cognitive, clinical, and neurodegenerative measures in autosomal-dominant Alzheimer's disease. Aging Cell. e13871. PMID 37291760 DOI: 10.1111/acel.13871  0.596
2023 Luo J, Ma Y, Agboola FJ, Grant E, Morris JC, McDade E, Fagan AM, Benzinger TLS, Hassenstab J, Bateman RJ, Perrin RJ, Gordon BA, Goyal M, Strain JF, Yakushev I, et al. Longitudinal Relationships of White Matter Hyperintensities and Alzheimer Disease Biomarkers Across the Adult Lifespan. Neurology. PMID 37202169 DOI: 10.1212/WNL.0000000000207378  0.608
2023 Brase L, You SF, D'Oliveira Albanus R, Del-Aguila JL, Dai Y, Novotny BC, Soriano-Tarraga C, Dykstra T, Fernandez MV, Budde JP, Bergmann K, Morris JC, Bateman RJ, Perrin RJ, McDade E, et al. Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers. Nature Communications. 14: 2314. PMID 37085492 DOI: 10.1038/s41467-023-37437-5  0.508
2023 Merrihew GE, Park J, Plubell D, Searle BC, Keene CD, Larson EB, Bateman R, Perrin RJ, Chhatwal JP, Farlow MR, McLean CA, Ghetti B, Newell KL, Frosch MP, Montine TJ, et al. A peptide-centric quantitative proteomics dataset for the phenotypic assessment of Alzheimer's disease. Scientific Data. 10: 206. PMID 37059743 DOI: 10.1038/s41597-023-02057-7  0.622
2023 Chen CD, McCullough A, Gordon B, Joseph-Mathurin N, Flores S, McKay NS, Hobbs DA, Hornbeck R, Fagan AM, Cruchaga C, Goate AM, Perrin RJ, Wang G, Li Y, Shi X, et al. Longitudinal head-to-head comparison of C-PiB and F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-β monoclonal antibodies in dominantly inherited Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging. PMID 37017737 DOI: 10.1007/s00259-023-06209-0  0.511
2023 You SF, Brase L, Filipello F, Iyer AK, Del-Aguila J, He J, D'Oliveira Albanus R, Budde J, Norton J, Gentsch J, Dräger NM, Sattler SM, Kampmann M, Piccio L, Morris JC, ... Perrin RJ, et al. MS4A4A modifies the risk of Alzheimer disease by regulating lipid metabolism and immune response in a unique microglia state. Medrxiv : the Preprint Server For Health Sciences. PMID 36798226 DOI: 10.1101/2023.02.06.23285545  0.328
2023 Millar PR, Gordon BA, Luckett PH, Benzinger TLS, Cruchaga C, Fagan AM, Hassenstab J, Perrin RJ, Schindler SE, Allegri RF, Day GS, Farlow MR, Mori H, Nübling G, Bateman RJ, et al. Multimodal brain age estimates relate to Alzheimer disease biomarkers and cognition in early stages: a cross-sectional observational study. Elife. 12. PMID 36607335 DOI: 10.7554/eLife.81869  0.551
2022 Chatterjee P, Vermunt L, Gordon BA, Pedrini S, Boonkamp L, Armstrong NJ, Xiong C, Singh AK, Li Y, Sohrabi HR, Taddei K, Molloy M, Benzinger TLS, Morris JC, Karch C, ... ... Perrin R, et al. Plasma glial fibrillary acidic protein in autosomal dominant Alzheimer's disease: Associations with Aβ-PET, neurodegeneration, and cognition. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36576155 DOI: 10.1002/alz.12879  0.634
2022 O'Connor A, Rice H, Barnes J, Ryan NS, Liu KY, Allegri RF, Berman S, Ringman JM, Cruchaga C, Farlow MR, Hassenstab J, Lee JH, Perrin RJ, Xiong C, Gordon B, et al. First presentation with neuropsychiatric symptoms in autosomal dominant Alzheimer's disease: the Dominantly Inherited Alzheimer's Network Study. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 36522155 DOI: 10.1136/jnnp-2022-329843  0.573
2022 Boerwinkle AH, Gordon BA, Wisch J, Flores S, Henson RL, Butt OH, McKay N, Chen CD, Benzinger TLS, Fagan AM, Handen BL, Christian BT, Head E, Mapstone M, Rafii MS, ... ... Perrin RJ, et al. Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study. The Lancet. Neurology. 22: 55-65. PMID 36517172 DOI: 10.1016/S1474-4422(22)00408-2  0.611
2022 Horie K, Barthélemy NR, Spina S, VandeVrede L, He Y, Paterson RW, Wright BA, Day GS, Davis AA, Karch CM, Seeley WW, Perrin RJ, Koppisetti RK, Shaikh F, Lago AL, et al. CSF tau microtubule-binding region identifies pathological changes in primary tauopathies. Nature Medicine. PMID 36424467 DOI: 10.1038/s41591-022-02075-9  0.614
2022 Drieu A, Du S, Storck SE, Rustenhoven J, Papadopoulos Z, Dykstra T, Zhong F, Kim K, Blackburn S, Mamuladze T, Harari O, Karch CM, Bateman RJ, Perrin R, Farlow M, et al. Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid. Nature. PMID 36352225 DOI: 10.1038/s41586-022-05397-3  0.52
2022 Novotny BC, Fernandez MV, Wang C, Budde JP, Bergmann K, Eteleeb AM, Bradley J, Webster C, Ebl C, Norton J, Gentsch J, Dube U, Wang F, Morris JC, Bateman RJ, ... Perrin RJ, et al. Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer's disease brains. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36251323 DOI: 10.1002/alz.12800  0.591
2022 Weiner MW, Veitch DP, Miller MJ, Aisen PS, Albala B, Beckett LA, Green RC, Harvey D, Jack CR, Jagust W, Landau SM, Morris JC, Nosheny R, Okonkwo OC, Perrin RJ, et al. Increasing participant diversity in AD research: Plans for digital screening, blood testing, and a community-engaged approach in the Alzheimer's Disease Neuroimaging Initiative 4. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36209495 DOI: 10.1002/alz.12797  0.42
2022 Joseph-Mathurin N, Llibre-Guerra JJ, Li Y, McCullough AA, Hofmann C, Wojtowicz J, Park E, Wang G, Preboske GM, Wang Q, Gordon BA, Chen CD, Flores S, Aggarwal NT, Berman SB, ... ... Perrin RJ, et al. Amyloid-related imaging abnormalities in the DIAN-TU-001 trial of gantenerumab and solanezumab: lessons from a trial in dominantly inherited Alzheimer disease. Annals of Neurology. PMID 36151869 DOI: 10.1002/ana.26511  0.545
2022 Cobigo Y, Goh MS, Wolf A, Staffaroni AM, Kornak J, Miller BL, Rabinovici GD, Seeley WW, Spina S, Boxer AL, Boeve BF, Wang L, Allegri R, Farlow M, Mori H, ... Perrin RJ, et al. Detection of emerging neurodegeneration using Bayesian linear mixed-effect modeling. Neuroimage. Clinical. 36: 103144. PMID 36030718 DOI: 10.1016/j.nicl.2022.103144  0.368
2022 Luo J, Agboola F, Grant E, Morris JC, Masters CL, Albert MS, Johnson SC, McDade EM, Fagan AM, Benzinger TLS, Hassenstab J, Bateman RJ, Perrin RJ, Wang G, Li Y, et al. Accelerated longitudinal changes and ordering of Alzheimer disease biomarkers across the adult lifespan. Brain : a Journal of Neurology. PMID 35925685 DOI: 10.1093/brain/awac238  0.595
2022 Strain JF, Brier MR, Tanenbaum A, Gordon BA, McCarthy JE, Dincer A, Marcus DS, Chhatwal JP, Graff-Radford NR, Day GS, la Fougère C, Perrin RJ, Salloway S, Schofield PR, Yakushev I, et al. Covariance-based vs. Correlation-based Functional Connectivity Dissociates Healthy Aging from Alzheimer Disease. Neuroimage. 119511. PMID 35914670 DOI: 10.1016/j.neuroimage.2022.119511  0.522
2022 Timsina J, Gomez-Fonseca D, Wang L, Do A, Western D, Alvarez I, Aguilar M, Pastor P, Henson RL, Herries E, Xiong C, Schindler SE, Fagan AM, Bateman RJ, Farlow M, ... ... Perrin R, et al. Comparative Analysis of Alzheimer's Disease Cerebrospinal Fluid Biomarkers Measurement by Multiplex SOMAscan Platform and Immunoassay-Based Approach. Journal of Alzheimer's Disease : Jad. PMID 35871346 DOI: 10.3233/JAD-220399  0.513
2022 Long JM, Coble DW, Xiong C, Schindler SE, Perrin RJ, Gordon BA, Benzinger TLS, Grant E, Fagan AM, Harari O, Cruchaga C, Holtzman DM, Morris JC. Preclinical Alzheimer's disease biomarkers accurately predict cognitive and neuropathological outcomes. Brain : a Journal of Neurology. PMID 35867858 DOI: 10.1093/brain/awac250  0.613
2022 Ali M, Sung YJ, Wang F, Fernández MV, Morris JC, Fagan AM, Blennow K, Zetterberg H, Heslegrave A, Johansson PM, Svensson J, Nellgård B, Lleó A, Alcolea D, Clarimon J, ... ... Perrin RJ, et al. Leveraging large multi-center cohorts of Alzheimer disease endophenotypes to understand the role of Klotho heterozygosity on disease risk. Plos One. 17: e0267298. PMID 35617280 DOI: 10.1371/journal.pone.0267298  0.422
2022 Vöglein J, Franzmeier N, Morris JC, Dieterich M, McDade E, Simons M, Preische O, Hofmann A, Hassenstab J, Benzinger TL, Fagan A, Noble JM, Berman SB, Graff-Radford NR, Ghetti B, ... ... Perrin RJ, et al. Patterns and implications of neurological examination findings in autosomal dominant Alzheimer disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35609137 DOI: 10.1002/alz.12684  0.573
2022 Couto B, Martinez-Valbuena I, Lee S, Alfradique-Dunham I, Perrin RJ, Perlmutter JS, Cruchaga C, Kim A, Visanji N, Sato C, Rogaeva E, Lang AE, Kovacs GG. Protracted Course-Progressive Supranuclear Palsy (PC-PSP). European Journal of Neurology. PMID 35384155 DOI: 10.1111/ene.15346  0.315
2022 Luckett PH, Chen C, Gordon BA, Wisch J, Berman SB, Chhatwal JP, Cruchaga C, Fagan AM, Farlow MR, Fox NC, Jucker M, Levin J, Masters CL, Mori H, Noble JM, ... ... Perrin RJ, et al. Biomarker clustering in autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35362200 DOI: 10.1002/alz.12661  0.625
2022 Strain JF, Barthelemy N, Horie K, Gordon BA, Kilgore C, Aschenbrenner A, Cruchaga C, Xiong C, Joseph-Mathurin N, Hassenstab J, Fagan AM, Li Y, Karch CM, Perrin RJ, Berman SB, et al. CSF Tau phosphorylation at Thr205 is associated with loss of white matter integrity in autosomal dominant Alzheimer disease. Neurobiology of Disease. 168: 105714. PMID 35358703 DOI: 10.1016/j.nbd.2022.105714  0.668
2022 Chen HH, Eteleeb A, Wang C, Fernandez MV, Budde JP, Bergmann K, Norton J, Wang F, Ebl C, Morris JC, Perrin RJ, Bateman RJ, McDade E, Xiong C, Goate A, et al. Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease. Acta Neuropathologica Communications. 10: 29. PMID 35246267 DOI: 10.1186/s40478-022-01328-5  0.532
2022 Chhatwal JP, Schultz SA, McDade E, Schultz AP, Liu L, Hanseeuw BJ, Joseph-Mathurin N, Feldman R, Fitzpatrick CD, Sparks KP, Levin J, Berman SB, Renton AE, Esposito BT, Fernandez MV, ... ... Perrin RJ, et al. Variant-dependent heterogeneity in amyloid β burden in autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analyses of an observational study. The Lancet. Neurology. 21: 140-152. PMID 35065037 DOI: 10.1016/S1474-4422(21)00375-6  0.627
2022 Miller RL, Dhavale DD, O'Shea JY, Andruska KM, Liu J, Franklin EE, Buddhala C, Loftin SK, Cirrito JR, Perrin RJ, Cairns NJ, Campbell MC, Perlmutter JS, Kotzbauer PT. Quantifying regional α -synuclein, amyloid β, and tau accumulation in lewy body dementia. Annals of Clinical and Translational Neurology. PMID 35060360 DOI: 10.1002/acn3.51482  0.606
2021 Weber CJ, Carrillo MC, Jagust W, Jack CR, Shaw LM, Trojanowski JQ, Saykin AJ, Beckett LA, Sur C, Rao NP, Mendez PC, Black SE, Li K, Iwatsubo T, Chang CC, ... ... Perrin RJ, et al. The Worldwide Alzheimer's Disease Neuroimaging Initiative: ADNI-3 updates and global perspectives. Alzheimer's & Dementia (New York, N. Y.). 7: e12226. PMID 35005206 DOI: 10.1002/trc2.12226  0.407
2021 Kothapalli SVVN, Benzinger TL, Aschenbrenner AJ, Perrin RJ, Hildebolt CF, Goyal MS, Fagan AM, Raichle ME, Morris JC, Yablonskiy DA. Quantitative Gradient Echo MRI Identifies Dark Matter as a New Imaging Biomarker of Neurodegeneration that Precedes Tisssue Atrophy in Early Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 34897083 DOI: 10.3233/JAD-210503  0.385
2021 Hubbard EE, Heil LR, Merrihew GE, Chhatwal JP, Farlow MR, McLean CA, Ghetti B, Newell KL, Frosch MP, Bateman RJ, Larson EB, Keene CD, Perrin RJ, Montine TJ, MacCoss MJ, et al. Does Data-Independent Acquisition Data Contain Hidden Gems? A Case Study Related to Alzheimer's Disease. Journal of Proteome Research. PMID 34818016 DOI: 10.1021/acs.jproteome.1c00558  0.583
2021 Farrell K, Kim S, Han N, Iida MA, Gonzalez EM, Otero-Garcia M, Walker JM, Richardson TE, Renton AE, Andrews SJ, Fulton-Howard B, Humphrey J, Vialle RA, Bowles KR, de Paiva Lopes K, ... ... Perrin RJ, et al. Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathologica. PMID 34719765 DOI: 10.1007/s00401-021-02379-z  0.36
2021 Koenig LN, LaMontagne P, Glasser MF, Bateman R, Holtzman D, Yakushev I, Chhatwal J, Day GS, Jack C, Mummery C, Perrin RJ, Gordon BA, Morris JC, Shimony JS, Benzinger TLS, et al. Regional age-related atrophy after screening for preclinical alzheimer disease. Neurobiology of Aging. 109: 43-51. PMID 34655980 DOI: 10.1016/j.neurobiolaging.2021.09.010  0.49
2021 Veitch DP, Weiner MW, Aisen PS, Beckett LA, DeCarli C, Green RC, Harvey D, Jack CR, Jagust W, Landau SM, Morris JC, Okonkwo O, Perrin RJ, Petersen RC, Rivera-Mindt M, et al. Using the Alzheimer's Disease Neuroimaging Initiative to improve early detection, diagnosis, and treatment of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34581485 DOI: 10.1002/alz.12422  0.451
2021 Chen CD, Joseph-Mathurin N, Sinha N, Zhou A, Li Y, Friedrichsen K, McCullough A, Franklin EE, Hornbeck R, Gordon B, Sharma V, Cruchaga C, Goate A, Karch C, McDade E, ... ... Perrin RJ, et al. Comparing amyloid-β plaque burden with antemortem PiB PET in autosomal dominant and late-onset Alzheimer disease. Acta Neuropathologica. PMID 34319442 DOI: 10.1007/s00401-021-02342-y  0.48
2021 Keret O, Staffaroni AM, Ringman JM, Cobigo Y, Goh SM, Wolf A, Allen IE, Salloway S, Chhatwal J, Brickman AM, Reyes-Dumeyer D, Bateman RJ, Benzinger TLS, Morris JC, Ances BM, ... ... Perrin RJ, et al. Pattern and degree of individual brain atrophy predicts dementia onset in dominantly inherited Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12197. PMID 34258377 DOI: 10.1002/dad2.12197  0.4
2021 Salloway S, Farlow M, McDade E, Clifford DB, Wang G, Llibre-Guerra JJ, Hitchcock JM, Mills SL, Santacruz AM, Aschenbrenner AJ, Hassenstab J, Benzinger TLS, Gordon BA, Fagan AM, Coalier KA, ... ... Perrin RJ, et al. A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease. Nature Medicine. PMID 34155411 DOI: 10.1038/s41591-021-01369-8  0.565
2021 Da Mesquita S, Papadopoulos Z, Dykstra T, Brase L, Farias FG, Wall M, Jiang H, Kodira CD, de Lima KA, Herz J, Louveau A, Goldman DH, Salvador AF, Onengut-Gumuscu S, Farber E, ... ... Perrin RJ, et al. Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy. Nature. PMID 33911285 DOI: 10.1038/s41586-021-03489-0  0.519
2021 Ewers M, Luan Y, Frontzkowski L, Neitzel J, Rubinski A, Dichgans M, Hassenstab J, Gordon BA, Chhatwal JP, Levin J, Schofield P, Benzinger TLS, Morris JC, Goate A, Karch CM, ... ... Perrin R, et al. Segregation of functional networks is associated with cognitive resilience in Alzheimer's disease. Brain : a Journal of Neurology. PMID 33725114 DOI: 10.1093/brain/awab112  0.605
2021 Joseph-Mathurin N, Wang G, Kantarci K, Jack CR, McDade E, Hassenstab J, Blazey TM, Gordon BA, Su Y, Chen G, Massoumzadeh P, Hornbeck RC, Allegri RF, Ances BM, Berman SB, ... ... Perrin RJ, et al. Longitudinal Accumulation of Cerebral Microhemorrhages in Dominantly Inherited Alzheimer Disease. Neurology. PMID 33495373 DOI: 10.1212/WNL.0000000000011542  0.549
2021 Grober E, Qi Q, Kuo L, Hassenstab J, Perrin RJ, Lipton RB. The Free and Cued Selective Reminding Test Predicts Braak Stage. Journal of Alzheimer's Disease : Jad. PMID 33492287 DOI: 10.3233/JAD-200980  0.39
2021 Grober E, Qi Q, Kuo L, Hassenstab J, Perrin RJ, Lipton RB. Stages of Objective Memory Impairment Predict Alzheimer's Disease Neuropathology: Comparison with the Clinical Dementia Rating Scale-Sum of Boxes. Journal of Alzheimer's Disease : Jad. PMID 33492286 DOI: 10.3233/JAD-200946  0.448
2021 Luckett PH, McCullough A, Gordon BA, Strain J, Flores S, Dincer A, McCarthy J, Kuffner T, Stern A, Meeker KL, Berman SB, Chhatwal JP, Cruchaga C, Fagan AM, Farlow MR, ... ... Perrin RJ, et al. Modeling autosomal dominant Alzheimer's disease with machine learning. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33480178 DOI: 10.1002/alz.12259  0.524
2021 Day GS, Gordon BA, McCullough A, Bucelli RC, Perrin RJ, Benzinger TLS, Ances BM. Flortaucipir (tau) PET in LGI1 antibody encephalitis. Annals of Clinical and Translational Neurology. PMID 33410601 DOI: 10.1002/acn3.51297  0.31
2020 Dincer A, Gordon BA, Hari-Raj A, Keefe SJ, Flores S, McKay NS, Paulick AM, Shady Lewis KE, Feldman RL, Hornbeck RC, Allegri R, Ances BM, Berman SB, Brickman AM, Brooks WS, ... ... Perrin RJ, et al. Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease. Neuroimage. Clinical. 28: 102491. PMID 33395982 DOI: 10.1016/j.nicl.2020.102491  0.536
2020 Walker JM, Richardson TE, Farrell K, Iida MA, Foong C, Shang P, Attems J, Ayalon G, Beach TG, Bigio EH, Budson A, Cairns NJ, Corrada M, Cortes E, Dickson DW, ... ... Perrin R, et al. Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy. Journal of Neuropathology and Experimental Neurology. PMID 33367843 DOI: 10.1093/jnen/nlaa153  0.333
2020 Ibanez L, Bahena JA, Yang C, Dube U, Farias FHG, Budde JP, Bergmann K, Brenner-Webster C, Morris JC, Perrin RJ, Cairns NJ, O'Donnell J, Álvarez I, Diez-Fairen M, Aguilar M, et al. Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease. Acta Neuropathologica Communications. 8: 196. PMID 33213513 DOI: 10.1186/s40478-020-01072-8  0.351
2020 Chen CD, Holden TR, Gordon BA, Franklin EE, Li Y, Coble DW, Luo H, Bateman RJ, Ances BM, Perrin RJ, Benzinger TLS, Cairns NJ, Morris JC. Ante- and postmortem tau in autosomal dominant and late-onset Alzheimer's disease. Annals of Clinical and Translational Neurology. PMID 33150749 DOI: 10.1002/acn3.51237  0.628
2020 Vermunt L, Dicks E, Wang G, Dincer A, Flores S, Keefe SJ, Berman SB, Cash DM, Chhatwal JP, Cruchaga C, Fox NC, Ghetti B, Graff-Radford NR, Hassenstab J, Karch CM, ... ... Perrin RJ, et al. Single-subject grey matter network trajectories over the disease course of autosomal dominant Alzheimer's disease. Brain Communications. 2: fcaa102. PMID 32954344 DOI: 10.1093/braincomms/fcaa102  0.547
2020 Luo J, Agboola F, Grant E, Masters CL, Albert MS, Johnson SC, McDade EM, Vöglein J, Fagan AM, Benzinger T, Massoumzadeh P, Hassenstab J, Bateman RJ, Morris JC, Perrin RJ, et al. Sequence of Alzheimer disease biomarker changes in cognitively normal adults: A cross-sectional study. Neurology. PMID 32873693 DOI: 10.1212/Wnl.0000000000010747  0.639
2020 Horie K, Barthélemy NR, Mallipeddi N, Li Y, Franklin EE, Perrin RJ, Bateman RJ, Sato C. Regional correlation of biochemical measures of amyloid and tau phosphorylation in the brain. Acta Neuropathologica Communications. 8: 149. PMID 32854776 DOI: 10.1186/S40478-020-01019-Z  0.547
2020 Aschenbrenner AJ, Petros J, McDade E, Wang G, Balota DA, Benzinger TL, Cruchaga C, Goate A, Xiong C, Perrin R, Fagan AM, Graff-Radford N, Ghetti B, Levin J, Weidinger E, et al. Relationships between big-five personality factors and Alzheimer's disease pathology in autosomal dominant Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12038. PMID 32587883 DOI: 10.1002/Dad2.12038  0.668
2020 Schultz SA, Strain JF, Adedokun A, Wang Q, Preische O, Kuhle J, Flores S, Keefe S, Dincer A, Ances BM, Berman SB, Brickman AM, Cash DM, Chhatwal J, Cruchaga C, ... ... Perrin RJ, et al. Serum neurofilament light chain levels are associated with white matter integrity in autosomal dominant Alzheimer's disease. Neurobiology of Disease. 104960. PMID 32522711 DOI: 10.1016/J.Nbd.2020.104960  0.546
2020 Barthélemy NR, Li Y, Joseph-Mathurin N, Gordon BA, Hassenstab J, Benzinger TLS, Buckles V, Fagan AM, Perrin RJ, Goate AM, Morris JC, Karch CM, Xiong C, Allegri R, Mendez PC, et al. A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease. Nature Medicine. 26: 398-407. PMID 32161412 DOI: 10.1038/S41591-020-0781-Z  0.65
2020 Aschenbrenner AJ, James BD, McDade E, Wang G, Lim YY, Benzinger TLS, Cruchaga C, Goate A, Xiong C, Perrin R, Buckles V, Allegri R, Berman SB, Chhatwal JP, Fagan A, et al. Awareness of genetic risk in the Dominantly Inherited Alzheimer Network (DIAN). Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 16: 219-228. PMID 31914221 DOI: 10.1002/Alz.12010  0.561
2019 Li Z, Farias FHG, Dube U, Del-Aguila JL, Mihindukulasuriya KA, Fernandez MV, Ibanez L, Budde JP, Wang F, Lake AM, Deming Y, Perez J, Yang C, Bahena JA, Qin W, ... ... Perrin RJ, et al. The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion. Acta Neuropathologica. PMID 31456032 DOI: 10.1007/S00401-019-02066-0  0.384
2019 Xu J, Sun J, Perrin RJ, Mach RH, Bales KR, Morris JC, Benzinger TLS, Holtzman DM. Translocator protein in late stage Alzheimer's disease and Dementia with Lewy bodies brains. Annals of Clinical and Translational Neurology. 6: 1423-1434. PMID 31402620 DOI: 10.1002/Acn3.50837  0.628
2019 Del-Aguila JL, Li Z, Dube U, Mihindukulasuriya KA, Budde JP, Fernandez MV, Ibanez L, Bradley J, Wang F, Bergmann K, Davenport R, Morris JC, Holtzman DM, Perrin RJ, Benitez BA, et al. A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain. Alzheimer's Research & Therapy. 11: 71. PMID 31399126 DOI: 10.1186/S13195-019-0524-X  0.567
2019 Han F, Perrin RJ, Wang Q, Wang Y, Perlmutter JS, Morris JC, Benzinger TLS, Xu J. Neuroinflammation and Myelin Status in Alzheimer's Disease, Parkinson's Disease, and Normal Aging Brains: A Small Sample Study. Parkinson's Disease. 2019: 7975407. PMID 31354934 DOI: 10.1155/2019/7975407  0.459
2019 Del-Aguila JL, Benitez BA, Li Z, Dube U, Mihindukulasuriya KA, Budde JP, Farias FHG, Fernández MV, Ibanez L, Jiang S, Perrin RJ, Cairns NJ, Morris JC, Harari O, Cruchaga C. TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers. Molecular Neurodegeneration. 14: 18. PMID 31068200 DOI: 10.1186/S13024-019-0319-3  0.463
2019 Navid J, Day GS, Strain J, Perrin RJ, Bucelli RC, Dincer A, Wisch JK, Soleimani-Meigooni D, Morris JC, Benzinger TLS, Ances BM. The Structural Signature of Sporadic Creutzfeldt-Jakob Disease. European Journal of Neurology. PMID 30735286 DOI: 10.1111/Ene.13930  0.451
2019 Day GS, Gordon BA, Perrin RJ, Ances BM. Author response: In vivo [F]-AV-1451 tau-PET imaging in sporadic Creutzfeldt-Jakob disease. Neurology. 92: 150. PMID 30643031 DOI: 10.1212/Wnl.0000000000006771  0.414
2019 Joseph-Mathurin N, Perrin RJ, Cairns NJ, Franklin EE, Xiong C, Preboske GM, Jack CR, Morris JC, Bateman R, Benzinger TLS. Ic-P-046: Cerebral Amyloid Angiopathy Is More Severe In Autosomal Dominant Ad Cases With Cerebral Microhemorrhages: Results From The Dian Study Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4208  0.54
2019 Day GS, Gordon BA, McCullough AA, Perrin RJ, Xu J, Ances BM. IC-P-166: TAU PET IMAGING IN LGI1 ENCEPHALITIS: DECIPHERING THE CONTRIBUTORS TO COGNITIVE IMPAIRMENT IN AUTOIMMUNE ENCEPHALITIS Alzheimer's & Dementia. 15: P131-P131. DOI: 10.1016/J.Jalz.2019.06.2801  0.326
2018 Schultz SA, Gordon BA, Mishra S, Su Y, Perrin RJ, Cairns NJ, Morris JC, Ances BM, Benzinger TLS. Widespread distribution of tauopathy in preclinical Alzheimer's disease. Neurobiology of Aging. 72: 177-185. PMID 30292840 DOI: 10.1016/J.Neurobiolaging.2018.08.022  0.412
2018 Gangishetti U, Christina Howell J, Perrin RJ, Louneva N, Watts KD, Kollhoff A, Grossman M, Wolk DA, Shaw LM, Morris JC, Trojanowski JQ, Fagan AM, Arnold SE, Hu WT. Non-beta-amyloid/tau cerebrospinal fluid markers inform staging and progression in Alzheimer's disease. Alzheimer's Research & Therapy. 10: 98. PMID 30253800 DOI: 10.1186/S13195-018-0426-3  0.549
2018 Day GS, Gordon BA, Perrin RJ, Cairns NJ, Beaumont H, Schwetye K, Ferguson C, Sinha N, Bucelli R, Musiek ES, Ghoshal N, Ponisio MR, Vincent B, Mishra S, Jackson K, et al. In vivo [18F]-AV-1451 tau-PET imaging in sporadic Creutzfeldt-Jakob disease. Neurology. PMID 29438042 DOI: 10.1212/Wnl.0000000000005064  0.352
2018 Vöglein J, Paumier KL, Cairns NJ, Franklin EE, Perrin RJ, Xiong C, Jucker M, Bateman RJ, Danek A, Morris JC, Levin J. P1-497: Clinical Correlates Of Lewy Body Pathology In Autosomal Dominant Alzheimer Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.507  0.469
2017 Gangishetti U, Perrin RJ, Arnold SE, Fagan AM, Morris JC, Trojanowski JQ, Hu WT. VALIDATING NON-AMYLOID, NON-TAU CSF BIOMARKERS FOR ALZHEIMER'S DISEASE IN THE PRE-SYMPTOMATIC, MCI, AND DEMENTIA STAGES: A MULTI-CENTER STUDY Alzheimer's & Dementia. 13: P1513-P1514. DOI: 10.1016/J.Jalz.2017.07.632  0.473
2017 Cairns NJ, Perrin RJ, Vincent BD, Baxter MR, Franklin EE, Bateman RJ, Morris JC. NEUROPATHOLOGIC HETEROGENEITY IN FAMILIAL AND LATE-ONSET ALZHEIMER'S DISEASE Alzheimer's & Dementia. 13: P877. DOI: 10.1016/J.Jalz.2017.07.255  0.383
2017 Day GS, Gordon BA, Perrin RJ, Cairns NJ, Schwetye KE, Ferguson CJ, Sinha N, Ponisio MR, Vincent BD, Beaumont H, Bucelli RC, Ghoshal N, Musiek ES, Morris JC, Benzinger TL, et al. FLORTAUCIPIR TAU-PET SPECIFICITY IS MAINTAINED IN PATIENTS WITH PATHOLOGICALLY CONFIRMED CREUTZFELDT-JAKOB DISEASE Alzheimer's & Dementia. 13: P900-P901. DOI: 10.1016/J.Jalz.2017.06.2555  0.313
2016 Cairns NJ, Perrin RJ, Franklin EE, Vincent BD, Baxter M, Morris JC. O3-04-03: Age-Related Neuropathology Helps Distinguish Autosomal Dominant from Late-Onset Alzheimer's Disease Alzheimer's & Dementia. 12: P291-P292. DOI: 10.1016/j.jalz.2016.06.526  0.339
2015 Leung YY, Toledo JB, Nefedov A, Polikar R, Raghavan N, Xie SX, Farnum M, Schultz T, Baek Y, Deerlin VV, Hu WT, Holtzman DM, Fagan AM, Perrin RJ, Grossman M, et al. Identifying amyloid pathology-related cerebrospinal fluid biomarkers for Alzheimer's disease in a multicohort study. Alzheimer's & Dementia (Amsterdam, Netherlands). 1: 339-348. PMID 26693175 DOI: 10.1016/J.Dadm.2015.06.008  0.614
2015 Holekamp TF, Mollman ME, Murphy RK, Kolar GR, Kramer NM, Derdeyn CP, Moran CJ, Perrin RJ, Rich KM, Lanzino G, Zipfel GJ. Dural arteriovenous fistula-induced thalamic dementia: report of 4 cases. Journal of Neurosurgery. 1-14. PMID 26587655 DOI: 10.3171/2015.5.Jns15473  0.314
2015 Franklin EE, Perrin RJ, Vincent B, Baxter M, Morris JC, Cairns NJ. Brain collection, standardized neuropathologic assessment, and comorbidity in Alzheimer's Disease Neuroimaging Initiative 2 participants. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 815-22. PMID 26194314 DOI: 10.1016/J.Jalz.2015.05.010  0.515
2015 Cairns NJ, Perrin RJ, Franklin EE, Carter D, Vincent B, Xie M, Bateman RJ, Benzinger T, Friedrichsen K, Brooks WS, Halliday GM, McLean C, Ghetti B, Morris JC, et al. Neuropathologic assessment of participants in two multi-center longitudinal observational studies: The Alzheimer Disease Neuroimaging Initiative (ADNI) and the Dominantly Inherited Alzheimer Network (DIAN). Neuropathology : Official Journal of the Japanese Society of Neuropathology. PMID 25964057 DOI: 10.1111/Neup.12205  0.612
2015 Cairns NJ, Perrin RJ, Franklin EE, Vincent B, Carter D, Morris JC. O4-02-01: Age-related neuropathology helps distinguish autosomal dominant from late-onset Alzheimer disease Alzheimer's & Dementia. 11: P269-P269. DOI: 10.1016/J.Jalz.2015.07.351  0.428
2015 Perrin RJ, Weng H, Bales KR, Morris JC, Benzinger TL, Fagan AM, Xiong C, Holtzman DM. O3-14-03: Novel fluid biomarkers for brain amyloid and dementia risk in presymptomatic Alzheimer disease Alzheimer's & Dementia. 11: P255-P255. DOI: 10.1016/J.Jalz.2015.07.317  0.605
2015 Franklin EE, Perrin RJ, Vincent B, Baxter M, Morris JC, Cairns NJ. Brain collection, standardized neuropathologic assessment, and comorbidity in Alzheimer's Disease Neuroimaging Initiative 2 participants Alzheimer's and Dementia. 11: 815-822. DOI: 10.1016/j.jalz.2015.05.010  0.359
2015 Leung YY, Toledo JB, Nefedov A, Polikar R, Raghavan N, Xie SX, Farnum M, Schultz T, Baek Y, Deerlin VV, Hu WT, Holtzman DM, Fagan AM, Perrin RJ, Grossman M, et al. Identifying amyloid pathology-related cerebrospinal fluid biomarkers for Alzheimer's disease in a multicohort study Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 1: 339-348. DOI: 10.1016/j.dadm.2015.06.008  0.601
2014 Cairns N, Perrin RJ, Householder E, Carter D, Vincent B, Morris J. P1-318: NEUROPATHOLOGIC HETEROGENEITY IN ALZHEIMER'S DISEASE NEUROIMAGING INITIATIVE (ADNI) SUBJECTS Alzheimer's & Dementia. 10: P428-P428. DOI: 10.1016/J.Jalz.2014.05.559  0.492
2013 Perrin RJ, Payton JE, Malone JP, Gilmore P, Davis AE, Xiong C, Fagan AM, Townsend RR, Holtzman DM. Quantitative label-free proteomics for discovery of biomarkers in cerebrospinal fluid: assessment of technical and inter-individual variation. Plos One. 8: e64314. PMID 23700471 DOI: 10.1371/Journal.Pone.0064314  0.416
2013 Leung YY, Toledo J, Nefedov A, Polikar R, Raghavan N, Xie S, Farnum M, Schultz T, Baek Y, Lobanov V, DiBernardo A, Deerlin VV, Kling M, Chen-Plotkin A, Mailman M, ... ... Perrin R, et al. Identifying multi-analyte CSF biomarkers for Alzheimer’s disease in a multi-cohort study Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.04.059  0.563
2012 Perrin RJ. Cerebrospinal fluid biomarkers for clinical trials: why markers for differential diagnosis are important. Archives of Neurology. 69: 1407-8. PMID 22926002 DOI: 10.1001/Archneurol.2012.2353  0.315
2012 Fagan AM, Perrin RJ. Upcoming candidate cerebrospinal fluid biomarkers of Alzheimer's disease. Biomarkers in Medicine. 6: 455-76. PMID 22917147 DOI: 10.2217/Bmm.12.42  0.547
2012 Hu WT, Holtzman DM, Fagan AM, Shaw LM, Perrin R, Arnold SE, Grossman M, Xiong C, Craig-Schapiro R, Clark CM, Pickering E, Kuhn M, Chen Y, Van Deerlin VM, McCluskey L, et al. Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease. Neurology. 79: 897-905. PMID 22855860 DOI: 10.1212/Wnl.0B013E318266Fa70  0.809
2011 Craig-Schapiro R, Kuhn M, Xiong C, Pickering EH, Liu J, Misko TP, Perrin RJ, Bales KR, Soares H, Fagan AM, Holtzman DM. Multiplexed immunoassay panel identifies novel CSF biomarkers for Alzheimer's disease diagnosis and prognosis. Plos One. 6: e18850. PMID 21526197 DOI: 10.1371/Journal.Pone.0018850  0.796
2011 Perrin RJ, Craig-Schapiro R, Malone JP, Shah AR, Gilmore P, Davis AE, Roe CM, Peskind ER, Li G, Galasko DR, Clark CM, Quinn JF, Kaye JA, Morris JC, Holtzman DM, et al. Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease. Plos One. 6: e16032. PMID 21264269 DOI: 10.1371/Journal.Pone.0016032  0.812
2011 Hu WT, Holtzman D, Clark C, Grossman M, Karlawish J, Fagan A, Lee V, Swenson F, Craig-Schapiro R, Perrin RJ, Soares H, Trojanowski J, Xiong C, Morris J, Shaw L, et al. P1-089: Plasma multianalyte profiling of mild cognitive impairment and Alzheimer's disease in two academic centers and the Alzheimer's Disease Neuroimaging Initiative Alzheimer's & Dementia. 7: S138-S138. DOI: 10.1016/J.Jalz.2011.05.368  0.8
2010 Craig-Schapiro R, Perrin RJ, Roe CM, Xiong C, Carter D, Cairns NJ, Mintun MA, Peskind ER, Li G, Galasko DR, Clark CM, Quinn JF, D'Angelo G, Malone JP, Townsend RR, et al. YKL-40: a novel prognostic fluid biomarker for preclinical Alzheimer's disease. Biological Psychiatry. 68: 903-12. PMID 21035623 DOI: 10.1016/J.Biopsych.2010.08.025  0.815
2010 Craig-Schapiro R, Perrin RJ, Roe CM, Grant EA, Carter D, Cairns NJ, Mintun MA, Peskind ER, Li G, Galasko DR, Clark CM, Quinn JF, D'Angelo G, Malone JP, Townsend RR, et al. P3-190: A novel diagnostic and prognostic fluid biomarker for early Alzheimer's disease: YKL-40 Alzheimer's & Dementia. 6: S506-S506. DOI: 10.1016/J.Jalz.2010.05.1688  0.794
2010 Perrin RJ, Craig-Schapiro R, Malone JP, Roe CM, Grant EA, Shah AR, Gilmore P, Davis AE, Peskind ER, Li G, Galasko DR, Quinn JF, Kaye JA, Clark CM, Morris JC, et al. P3-172: Identification and validation of novel cerebrospinal fluid protein biomarkers for early Alzheimer's disease using proteomics and ELISA: a multi-institutional collaborative study Alzheimer's & Dementia. 6: S500-S500. DOI: 10.1016/J.Jalz.2010.05.1670  0.749
2009 Perrin RJ, Fagan AM, Holtzman DM. Multimodal techniques for diagnosis and prognosis of Alzheimer's disease. Nature. 461: 916-22. PMID 19829371 DOI: 10.1038/Nature08538  0.648
2009 Ghoshal N, Cali I, Perrin RJ, Josephson SA, Sun N, Gambetti P, Morris JC. Codistribution of amyloid beta plaques and spongiform degeneration in familial Creutzfeldt-Jakob disease with the E200K-129M haplotype. Archives of Neurology. 66: 1240-6. PMID 19822779 DOI: 10.1001/Archneurol.2009.224  0.389
2008 Perrin RJ, Malone JP, Shah AR, Craig-Schapiro R, Gilmore P, Davis AE, Peskind ER, Li G, Galasko DR, Quinn JF, Kaye JA, Clark CM, Morris JC, Holtzman DM, Townsend RR, et al. P3-088: Identification of potential biomarkers for Alzheimer's disease in cerebrospinal fluid using two-dimensional difference gel electrophoresis and tandem mass spectrometry: A multi-institutional collaborative study Alzheimer's & Dementia. 4: T543-T543. DOI: 10.1016/J.Jalz.2008.05.1652  0.781
2008 Ghoshal N, Perrin RJ, Josephson SA, Sun NA, Clark CM, Cali I, Gambetti P, Morris JC. P2-207: Co-distribution of Aβ plaques and spongiform degeneration in familial Creutzfeldt-Jakob disease with E200K-129M haplotype Alzheimer's & Dementia. 4: T431-T432. DOI: 10.1016/J.Jalz.2008.05.1282  0.383
2004 Payton JE, Perrin RJ, Woods WS, George JM. Structural determinants of PLD2 inhibition by alpha-synuclein. Journal of Molecular Biology. 337: 1001-9. PMID 15033366 DOI: 10.1016/j.jmb.2004.02.014  0.384
2003 Perrin RJ, Payton JE, Barnett DH, Wraight CL, Woods WS, Ye L, George JM. Epitope mapping and specificity of the anti-alpha-synuclein monoclonal antibody Syn-1 in mouse brain and cultured cell lines. Neuroscience Letters. 349: 133-5. PMID 12946570 DOI: 10.1016/S0304-3940(03)00781-X  0.679
2001 Payton JE, Perrin RJ, Clayton DF, George JM. Protein-protein interactions of alpha-synuclein in brain homogenates and transfected cells. Brain Research. Molecular Brain Research. 95: 138-45. PMID 11687285 DOI: 10.1016/S0169-328X(01)00257-1  0.574
2001 Perrin RJ, Woods WS, Clayton DF, George JM. Exposure to long chain polyunsaturated fatty acids triggers rapid multimerization of synucleins. The Journal of Biological Chemistry. 276: 41958-62. PMID 11553616 DOI: 10.1074/jbc.M105022200  0.628
2000 Perrin RJ, Woods WS, Clayton DF, George JM. Interaction of human alpha-Synuclein and Parkinson's disease variants with phospholipids. Structural analysis using site-directed mutagenesis. The Journal of Biological Chemistry. 275: 34393-8. PMID 10952980 DOI: 10.1074/jbc.M004851200  0.594
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