Hal E. Broxmeyer - Publications

Affiliations: 
Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Molecular Biology, Immunology, Biochemistry

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Year Citation  Score
2024 Guo B, Huang X, Chen Y, Broxmeyer HE. Ex Vivo Expansion and Homing of Human Cord Blood Hematopoietic Stem Cells. Advances in Experimental Medicine and Biology. 1442: 85-104. PMID 38228960 DOI: 10.1007/978-981-99-7471-9_6  0.302
2023 Di Meo F, Iyer A, Akama K, Cheng R, Yu C, Cesarano A, Kurihara N, Tenshin H, Aljoufi A, Marino S, Soni RK, Roda J, Sissons J, Vu LP, Guzman M, ... ... Broxmeyer HE, et al. A target discovery pipeline identified ILT3 as a target for immunotherapy of multiple myeloma. Cell Reports. Medicine. 4: 101110. PMID 37467717 DOI: 10.1016/j.xcrm.2023.101110  0.315
2022 Wang X, Cooper S, Broxmeyer HE, Kapur R. Transient regulation of RNA methylation in human hematopoietic stem cells promotes their homing and engraftment. Leukemia. PMID 36460765 DOI: 10.1038/s41375-022-01761-4  0.35
2022 Cooper SH, Capitano ML, Broxmeyer HE. Experimental Models of Mouse and Human Hematopoietic Stem Cell Transplantation. Methods in Molecular Biology (Clifton, N.J.). 2567: 205-232. PMID 36255704 DOI: 10.1007/978-1-0716-2679-5_14  0.426
2022 Chang Y, Syahirah R, Wang X, Jin G, Torregrosa-Allen S, Elzey BD, Hummel SN, Wang T, Li C, Lian X, Deng Q, Broxmeyer HE, Bao X. Engineering chimeric antigen receptor neutrophils from human pluripotent stem cells for targeted cancer immunotherapy. Cell Reports. 40: 111128. PMID 35858579 DOI: 10.1016/j.celrep.2022.111128  0.31
2022 Aljoufi A, Zhang C, Ropa J, Chang W, Palam LR, Cooper S, Ramdas B, Capitano ML, Broxmeyer HE, Kapur R. Physioxia induced Downregulation of Tet2 in Hematopoietic Stem Cells contributes to Enhanced Self-renewal. Blood. PMID 35772013 DOI: 10.1182/blood.2022015499  0.324
2022 Wang X, Cooper S, Broxmeyer HE, Kapur R. Nuclear translocation of TFE3 under hypoxia enhances the engraftment of human hematopoietic stem cells. Leukemia. PMID 35732828 DOI: 10.1038/s41375-022-01628-8  0.352
2022 Chang Y, Syahirah R, Oprescu SN, Wang X, Jung J, Cooper SH, Torregrosa-Allen S, Elzey BD, Hsu AY, Randolph LN, Sun Y, Kuang S, Broxmeyer HE, Deng Q, Lian X, et al. Chemically-defined generation of human hemogenic endothelium and definitive hematopoietic progenitor cells. Biomaterials. 285: 121569. PMID 35567999 DOI: 10.1016/j.biomaterials.2022.121569  0.431
2022 Ropa J, Cooper S, Broxmeyer HE. Leukemia Inhibitory Factor Promotes Survival of Hematopoietic Progenitors Ex Vivo and Is Post-Translationally Regulated by DPP4. Stem Cells (Dayton, Ohio). PMID 35293568 DOI: 10.1093/stmcls/sxac004  0.348
2022 Broxmeyer HE, Ropa J, Capitano ML, Cooper S, Racioppi L, Sankar U. CaMKK2 Knockout Bone Marrow Cells Collected/Processed in Low Oxygen (Physioxia) Suggests CaMKK2 as a Hematopoietic Stem to Progenitor Differentiation Fate Determinant. Stem Cell Reviews and Reports. PMID 35262902 DOI: 10.1007/s12015-021-10306-8  0.384
2021 Naidu SR, Capitano M, Ropa J, Cooper S, Huang X, Broxmeyer HE. Chromatin remodeling subunit BRM and valine regulate hematopoietic stem/progenitor cell function and self-renewal via intrinsic and extrinsic effects. Leukemia. PMID 34599272 DOI: 10.1038/s41375-021-01426-8  0.431
2021 Broxmeyer HE, Cooper SH, Ropa J. CXCL15/Lungkine has suppressive activity on proliferation and expansion of multi-potential, erythroid, granulocyte and macrophage progenitors in S-phase specific manner. Blood Cells, Molecules & Diseases. 91: 102594. PMID 34520986 DOI: 10.1016/j.bcmd.2021.102594  0.406
2021 Chen Y, Fang S, Ding Q, Jiang R, He J, Wang Q, Jin Y, Huang X, Liu S, Capitano M, Trinh T, Teng Y, Meng Q, Wan J, Broxmeyer H, et al. ADGRG1 enriches for functional human hematopoietic stem cells following ex vivo expansion-induced mitochondrial oxidative stress. The Journal of Clinical Investigation. PMID 34464351 DOI: 10.1172/JCI148329  0.344
2021 Broxmeyer HE, Cooper S, Blum JS. Expression of gilt acts as a positive regulator of mouse hematopoietic progenitor cells. Blood Cells, Molecules & Diseases. 90: 102574. PMID 34015674 DOI: 10.1016/j.bcmd.2021.102574  0.413
2021 Trinh T, Broxmeyer HE. Role for Leptin and Leptin Receptors in Stem Cells During Health and Diseases. Stem Cell Reviews and Reports. PMID 33598894 DOI: 10.1007/s12015-021-10132-y  0.393
2021 Jin Y, Huang J, Wang Q, He J, Teng Y, Jiang R, Broxmeyer HE, Guo B. RXR Negatively Regulates Ex Vivo Expansion of Human Cord Blood Hematopoietic Stem and Progenitor Cells. Stem Cell Reviews and Reports. PMID 33527324 DOI: 10.1007/s12015-021-10124-y  0.411
2020 Broxmeyer H. Players in Drug-Resistant Leukemia Stem/Initiating Cells and Immunity in Patients with CML in Context of Oxygen Levels: Would Collecting/Processing Cells in Hypoxia Offer Additional Information? A Next Frontier of Investigation. Blood Cancer Discovery. 1: 13-15. PMID 34661136 DOI: 10.1158/2643-3249.BCD-20-0034  0.317
2020 Trinh T, Ropa J, Aljoufi A, Cooper S, Sinn A, Srour EF, Broxmeyer HE. Leptin receptor, a surface marker for a subset of highly engrafting long-term functional hematopoietic stem cells. Leukemia. PMID 33159180 DOI: 10.1038/s41375-020-01079-z  0.411
2020 Namburi S, Broxmeyer HE, Hong CS, Whiteside TL, Boyiadzis M. DPP4 exosomes in AML patients' plasma suppress proliferation of hematopoietic progenitor cells. Leukemia. PMID 33139859 DOI: 10.1038/s41375-020-01047-7  0.316
2020 Ropa J, Cooper S, Capitano ML, Van't Hof W, Broxmeyer HE. Human Hematopoietic Stem, Progenitor, and Immune Cells Respond Ex Vivo to SARS-CoV-2 Spike Protein. Stem Cell Reviews and Reports. PMID 33089452 DOI: 10.1007/s12015-020-10056-z  0.377
2020 Wang X, Broxmeyer HE. DUSP16 is a regulator of human hematopoietic stem and progenitor cells and promotes their expansion ex vivo. Leukemia. PMID 33077868 DOI: 10.1038/s41375-020-01064-6  0.37
2020 Nelson MH, Knochelmann HM, Bailey SR, Huff LW, Bowers JS, Majchrzak-Kuligowska K, Wyatt MM, Rubinstein MP, Mehrotra S, Nishimura MI, Armeson KE, Giresi PG, Zilliox MJ, Broxmeyer HE, Paulos CM. Identification of human CD4 T cell populations with distinct antitumor activity. Science Advances. 6. PMID 32937437 DOI: 10.1126/Sciadv.Aba7443  0.387
2020 Broxmeyer HE, Capitano ML, Cooper S, Potchanant ES, Clapp DW. Numbers of long-term hematopoietic stem cells from bone marrow of fanca and fancc knockout mice can be greatly enhanced by their collection and processing in physioxia conditions. Blood Cells, Molecules & Diseases. 86: 102492. PMID 32896825 DOI: 10.1016/J.Bcmd.2020.102492  0.46
2020 Shao L, Elujoba-Bridenstine A, Zink KE, Sanchez LM, Cox BJ, Pollok KE, Sinn A, Bailey BJ, Sims E, Cooper S, Broxmeyer HE, Pajcini KV, Tamplin OJ. The neurotransmitter receptor Gabbr1 regulates proliferation and function of hematopoietic stem and progenitor cells. Blood. PMID 32881992 DOI: 10.1182/Blood.2019004415  0.495
2020 Shin D, Huang X, Gil CH, Aljoufi A, Ropa J, Broxmeyer HE. Physioxia enhances T cell development ex vivo from human hematopoietic stem and progenitor cells. Stem Cells (Dayton, Ohio). PMID 32761664 DOI: 10.1002/Stem.3259  0.494
2020 Aljoufi A, Cooper S, Broxmeyer HE. Collection and Processing of Mobilized Mouse Peripheral Blood at Lowered Oxygen Tension Yields Enhanced Numbers of Hematopoietic Stem Cells. Stem Cell Reviews and Reports. PMID 32748332 DOI: 10.1007/S12015-020-10021-W  0.463
2020 Zhang J, Huang X, Guo B, Cooper S, Capitano ML, Johnson TC, Siegel DR, Broxmeyer HE. Effects of Eupalinilide E and UM171, alone and in combination on cytokine stimulated ex-vivo expansion of human cord blood hematopoietic stem cells. Blood Cells, Molecules & Diseases. 84: 102457. PMID 32604056 DOI: 10.1016/J.Bcmd.2020.102457  0.534
2020 Broxmeyer HE, Cooper S, Capitano ML. Enhanced Collection of Phenotypic and Engrafting Human Cord Blood Hematopoietic Stem Cells at 4°C. Stem Cells (Dayton, Ohio). PMID 32535978 DOI: 10.1002/Stem.3243  0.482
2020 Ropa J, Broxmeyer HE. An expanded role for dipeptidyl peptidase 4 in cell regulation. Current Opinion in Hematology. 27: 215-224. PMID 32487805 DOI: 10.1097/Moh.0000000000000590  0.364
2020 Capitano ML, Griesenauer B, Guo B, Cooper S, Paczesny S, Broxmeyer HE. The IL-33 Receptor/ST2 acts as a positive regulator of functional mouse bone marrow hematopoietic stem and progenitor cells. Blood Cells, Molecules & Diseases. 84: 102435. PMID 32408242 DOI: 10.1016/J.Bcmd.2020.102435  0.508
2020 Broxmeyer HE, Parker GC. Impact of COVID-19 and Future Emerging Viruses on Hematopoietic Cell Transplantation and Other Cellular Therapies. Stem Cells and Development. PMID 32237972 DOI: 10.1089/Scd.2020.0064  0.301
2020 Xu D, Yang M, Capitano M, Guo B, Liu S, Wan J, Broxmeyer HE, Huang X. Pharmacological activation of nitric oxide signaling promotes human hematopoietic stem cell homing and engraftment. Leukemia. PMID 32127640 DOI: 10.1038/S41375-020-0787-Z  0.418
2019 Broxmeyer HE. Quickly attainable and highly engrafting hematopoietic stem cells. Blood Science (Baltimore, Md.). 1: 113-115. PMID 35402793 DOI: 10.1097/BS9.0000000000000003  0.352
2019 Chen S, Wang Q, Yu H, Capitano ML, Vemula S, Nabinger SC, Gao R, Yao C, Kobayashi M, Geng Z, Fahey A, Henley D, Liu SZ, Barajas S, Cai W, ... ... Broxmeyer HE, et al. Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway. Nature Communications. 10: 5649. PMID 31827082 DOI: 10.1038/S41467-019-13542-2  0.34
2019 Huang X, Guo B, Capitano M, Broxmeyer HE. Past, present, and future efforts to enhance the efficacy of cord blood hematopoietic cell transplantation. F1000research. 8. PMID 31723413 DOI: 10.12688/F1000Research.20002.1  0.439
2019 Ni F, Yu WM, Li Z, Graham DK, Jin L, Kang S, Rossi MR, Li S, Broxmeyer HE, Qu CK. Critical role of ASCT2-mediated amino acid metabolism in promoting leukaemia development and progression. Nature Metabolism. 1: 390-403. PMID 31535081 DOI: 10.1038/s42255-019-0039-6  0.32
2019 Broxmeyer HE. Hematopoietic Stem Cell Intracellular Levels of Ca to the Rescue! What Next? Cell Stem Cell. 25: 171-173. PMID 31374196 DOI: 10.1016/J.Stem.2019.07.003  0.412
2019 Chen Y, Yao C, Teng Y, Jiang R, Huang X, Liu S, Wan J, Broxmeyer HE, Guo B. Phorbol ester induced ex vivo expansion of rigorously-defined phenotypic but not functional human cord blood hematopoietic stem cells: a cautionary tale demonstrating that phenotype does not always recapitulate stem cell function. Leukemia. PMID 31350528 DOI: 10.1038/S41375-019-0528-3  0.48
2019 Zhang J, Ghosh J, Mohamad SF, Zhang C, Huang X, Capitano ML, Gunawan AM, Cooper S, Guo B, Cai Q, Broxmeyer HE, Srour EF. CD166 engagement augments mouse and human hematopoietic progenitor function via activation of stemness and cell cycle pathways. Stem Cells (Dayton, Ohio). PMID 31260147 DOI: 10.1002/Stem.3053  0.419
2019 Capitano ML, Mor-Vaknin N, Saha AK, Cooper S, Legendre M, Guo H, Contreras-Galindo R, Kappes F, Sartor MA, Lee CT, Huang X, Markovitz DM, Broxmeyer HE. Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling. The Journal of Clinical Investigation. 130. PMID 31107242 DOI: 10.1172/Jci127460  0.459
2019 Mayani H, Wagner JE, Broxmeyer HE. Cord blood research, banking, and transplantation: achievements, challenges, and perspectives. Bone Marrow Transplantation. PMID 31089283 DOI: 10.1038/S41409-019-0546-9  0.426
2019 Huang X, Broxmeyer HE. Progress towards improving homing and engraftment of hematopoietic stem cells for clinical transplantation. Current Opinion in Hematology. PMID 31045644 DOI: 10.1097/Moh.0000000000000510  0.43
2019 Naidu SR, Capitano ML, Cooper S, Huang X, Broxmeyer HE. Chromatin Remodeling Subunit Brm Regulates Hematopoietic Stem Cell Self-Renewal By Limiting Intracellular Valine Levels Blood. 134: 3702-3702. DOI: 10.1182/Blood-2019-128867  0.549
2019 Capitano ML, Sammour Y, Legendre M, Cooper S, Markovitz D, Broxmeyer HE. Hematopoietic Stem and Progenitor Cells Manifest Direct Migration Towards Secreted DEK in a CXCR2- and G Protein Signaling-Dependent Manner Blood. 134: 1196-1196. DOI: 10.1182/Blood-2019-128738  0.5
2019 Trinh T, Cooper S, Aljoufi A, Srour EF, Broxmeyer HE. Leptin Receptor As a Functional Marker for Long-Term Repopulating Hematopoietic Stem Cells Blood. 134: 3712-3712. DOI: 10.1182/Blood-2019-128659  0.521
2019 Capitano ML, Cooper S, Guo B, Huang X, Sampson C, Mohamad S, Srour EF, Orschell CM, Broxmeyer HE. Collection and Processing of Bone Marrow at 3% Oxygen Significantly Alters the Manifestation of Aged Mouse Hematopoietic Stem Cell Phenotype Blood. 134: 1202-1202. DOI: 10.1182/Blood-2019-128642  0.429
2018 Huang X, Trinh T, Aljoufi A, Broxmeyer HE. Hypoxia Signaling Pathway in Stem Cell Regulation: Good and Evil. Current Stem Cell Reports. 4: 149-157. PMID 31275803 DOI: 10.1007/S40778-018-0127-7  0.443
2018 Pelus LM, Broxmeyer HE. Peripheral blood stem cell mobilization; a look ahead. Current Stem Cell Reports. 4: 273-281. PMID 31131207 DOI: 10.1007/S40778-018-0141-9  0.447
2018 Ha TW, Kang HS, Kim TH, Kwon JH, Kim HK, Ryu A, Jeon H, Han J, Broxmeyer HE, Hwang Y, Lee YK, Lee MR. MiR-9 Controls Chemotactic Activity of Cord Blood CD34⁺ Cells by Repressing CXCR4 Expression. International Journal of Stem Cells. PMID 30343551 DOI: 10.15283/Ijsc18057  0.363
2018 Hu P, Nebreda AR, Hanenberg H, Kinnebrew GH, Ivan M, Yoder MC, Filippi MD, Broxmeyer HE, Kapur R. P38α/JNK signaling restrains erythropoiesis by suppressing Ezh2-mediated epigenetic silencing of Bim. Nature Communications. 9: 3518. PMID 30158520 DOI: 10.1038/s41467-018-05955-2  0.32
2018 Huang X, Broxmeyer HE. mA reader suppression bolsters HSC expansion. Cell Research. PMID 30131512 DOI: 10.1038/S41422-018-0081-Z  0.314
2018 Huang X, Guo B, Liu S, Wan J, Broxmeyer HE. Neutralizing negative epigenetic regulation by HDAC5 enhances human haematopoietic stem cell homing and engraftment. Nature Communications. 9: 2741. PMID 30013077 DOI: 10.1038/S41467-018-05178-5  0.5
2018 Broxmeyer HE. Enhancement of stem cell engraftment on a WHIM. The Journal of Clinical Investigation. PMID 29939159 DOI: 10.1172/Jci121857  0.433
2018 Barwinska D, Oueini H, Poirier C, Albrecht ME, Bogatcheva NV, Justice MJ, Saliba J, Schweitzer KS, Broxmeyer HE, March KL, Petrache I. AMD3100 ameliorates cigarette smoke-induced emphysema-like manifestations in mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 29745251 DOI: 10.1152/Ajplung.00185.2018  0.316
2018 Guo B, Huang X, Broxmeyer HE. Enhancing human cord blood hematopoietic stem cell engraftment by targeting nuclear hormone receptors. Current Opinion in Hematology. PMID 29608487 DOI: 10.1097/Moh.0000000000000429  0.442
2018 Liu Y, Huang X, Timani KA, Broxmeyer HE, He JJ. Regulation of Constitutive Tip110 Expression in Human Cord Blood CD34Cells Through Selective Usage of the Proximal and Distal Polyadenylation Sites Within the 3'Untranslated Region. Stem Cells and Development. PMID 29583087 DOI: 10.1089/Scd.2017.0197  0.424
2018 Liu Y, Huang X, Timani KA, Broxmeyer HE, He JJ. miRNA regulation of Tip110 expression and self-renewal and differentiation of human CD34+ hematopoietic cells. Oncotarget. 9: 4823-4832. PMID 29435144 DOI: 10.18632/Oncotarget.23572  0.349
2018 Cai Q, Capitano M, Huang X, Guo B, Cooper S, Broxmeyer HE. Combinations of antioxidants and/or of epigenetic enzyme inhibitors allow for enhanced collection of mouse bone marrow hematopoietic stem cells in ambient air. Blood Cells, Molecules & Diseases. PMID 29422232 DOI: 10.1016/J.Bcmd.2018.01.005  0.454
2018 Guo B, Huang X, Lee MR, Lee SA, Broxmeyer HE. Antagonism of PPAR-γ signaling expands human hematopoietic stem and progenitor cells by enhancing glycolysis. Nature Medicine. PMID 29377004 DOI: 10.1038/Nm.4477  0.512
2018 Ghosh J, Zhang J, Zhang C, Huang X, Mohamad SF, Capitano ML, Gunawan AM, Cooper S, Guo B, Cai Q, Broxmeyer HE, Srour EF. CD166 Engagement Augments Mouse and Human Hematopoietic Stem and Progenitor Function Via Activation of Stem Cell-Associated and Cell Cycle Pathways Blood. 132: 1282-1282. DOI: 10.1182/Blood-2018-99-119251  0.389
2018 Namburi S, Broxmeyer HE, Whiteside TL, Boyiadzis M. Persistence of Exosomes in Patients with Acute Myeloid Leukemia in Complete Remission Suppresses Hematopoiesis Blood. 132: 3850-3850. DOI: 10.1182/Blood-2018-99-115354  0.401
2018 Huang X, Guo B, Capitano ML, Broxmeyer HE. Nitric Oxide Promotes Human Hematopoietic Stem Cell Homing and Engraftment Via cGMP-Pkg Signaling Blood. 132: 807-807. DOI: 10.1182/Blood-2018-99-112993  0.496
2018 Capitano M, Orschell C, Broxmeyer H. Mitochondria and hematopoietic stem cells Free Radical Biology and Medicine. 120: S17. DOI: 10.1016/J.Freeradbiomed.2018.04.074  0.424
2017 Farag SS, Nelson R, Cairo MS, O'Leary HA, Zhang S, Huntley C, Delgado D, Schwartz J, Zaid MA, Abonour R, Robertson M, Broxmeyer H. High-dose sitagliptin for systemic inhibition of dipeptidylpeptidase-4 to enhance engraftment of single cord umbilical cord blood transplantation. Oncotarget. 8: 110350-110357. PMID 29299152 DOI: 10.18632/Oncotarget.22739  0.322
2017 Chen S, Gao R, Yao C, Kobayashi M, Liu SZ, Yoder MC, Broxmeyer H, Kapur R, Boswell HS, Mayo LD, Liu Y. Genotoxic stresses promote clonal expansion of hematopoietic stem cells expressing mutant p53. Leukemia. PMID 29263439 DOI: 10.1038/Leu.2017.325  0.402
2017 Park Y, Lee J, Kwak JY, Noh K, Yim E, Kim HK, Kim YJ, Broxmeyer HE, Kim JA. Fractalkine induces angiogenic potential in CX3CR1-expressing monocytes. Journal of Leukocyte Biology. PMID 28978662 DOI: 10.1189/Jlb.1A0117-002Rr  0.398
2017 Park J, Lee JW, Cooper SC, Broxmeyer HE, Cannon JR, Kim CH. Parkinson disease-associated LRRK2 G2019S transgene disrupts marrow myelopoiesis and peripheral Th17 response. Journal of Leukocyte Biology. PMID 28751472 DOI: 10.1189/Jlb.1A0417-147Rr  0.388
2017 Aljitawi OS, Laughlin M, Broxmeyer H. Erythropoietin in umbilical cord blood transplantation: Defining the role and implications. Expert Review of Hematology. PMID 28665231 DOI: 10.1080/17474086.2017.1350168  0.312
2017 Hwang Y, Broxmeyer HE, Lee MR. Generating autologous hematopoietic cells from human-induced pluripotent stem cells through ectopic expression of transcription factors. Current Opinion in Hematology. PMID 28383341 DOI: 10.1097/Moh.0000000000000343  0.522
2017 Park SJ, Lee SA, Prasain N, Bae D, Kang H, Ha T, Kim JS, Hong KS, Mantel C, Moon SH, Broxmeyer HE, Lee MR. Metabolome Profiling of Partial and Fully Reprogrammed Induced Pluripotent Stem Cells. Stem Cells and Development. PMID 28346802 DOI: 10.1089/Scd.2016.0320  0.436
2017 O'Leary HA, Capitano M, Cooper S, Mantel C, Boswell HS, Kapur R, Ramdas B, Chan R, Deng L, Qu CK, Broxmeyer HE. DPP4 truncated GM-CSF & IL-3 manifest distinct receptor binding & regulatory functions compared to their full length forms. Leukemia. PMID 28344320 DOI: 10.1038/Leu.2017.98  0.433
2017 Capitano ML, Broxmeyer HE. A role for intracellular and extracellular DEK in regulating hematopoiesis. Current Opinion in Hematology. PMID 28306668 DOI: 10.1097/Moh.0000000000000344  0.449
2017 Guo B, Huang X, Cooper S, Broxmeyer HE. Glucocorticoid hormone-induced chromatin remodeling enhances human hematopoietic stem cell homing and engraftment. Nature Medicine. PMID 28263313 DOI: 10.1038/Nm.4298  0.499
2017 Namburi S, Broxmeyer HE, Whiteside TL, Boyiadzis M. Plasma-Derived Exosomes in Acute Myeloid Leukemia Carry Dipeptidylpeptidase-4 and Inhibit Normal Human Hematopoiesis Blood. 130: 1164-1164. DOI: 10.1182/Blood.V130.Suppl_1.1164.1164  0.451
2017 Kim J, Kwak J, Lee J, Park Y, Broxmeyer HE. Fractalkine Treated of CD11b+CX3CR1+ Monocytes Promotes Angiogenesis through Pigment Epithelium-Derived Factor Blood. 130: 1026-1026. DOI: 10.1182/Blood.V130.Suppl_1.1026.1026  0.326
2016 Dong L, Yu WM, Zheng H, Loh ML, Bunting ST, Pauly M, Huang G, Zhou M, Broxmeyer HE, Scadden DT, Qu CK. Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment. Nature. PMID 27783593 DOI: 10.1038/Nature20131  0.442
2016 Aljitawi OS, Paul S, Ganguly A, Lin TL, Ganguly S, Vielhauer G, Capitano ML, Cantelina A, Lipe B, Mahnken JD, Wise A, Berry A, Singh AK, Shune L, Lominska C, ... ... Broxmeyer HE, et al. Erythropoietin modulation is associated with improved homing and engraftment post umbilical cord blood transplantation. Blood. PMID 27760758 DOI: 10.1182/Blood-2016-05-715292  0.466
2016 Lakhter AJ, Hamilton J, Konger RL, Brustovetsky N, Broxmeyer HE, Naidu SR. Glucose-independent acetate metabolism promotes melanoma cell survival and tumor growth. The Journal of Biological Chemistry. PMID 27539851 DOI: 10.1074/Jbc.M115.712166  0.353
2016 Broxmeyer HE. Enhancing the efficacy of engraftment of cord blood for hematopoietic cell transplantation. Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society For Haemapheresis. PMID 27211041 DOI: 10.1016/J.Transci.2016.05.013  0.46
2016 Messina-Graham S, Broxmeyer H. SDF-1/CXCL12 modulates mitochondrial respiration of immature blood cells in a bi-phasic manner. Blood Cells, Molecules & Diseases. 58: 13-8. PMID 27067482 DOI: 10.1016/J.Bcmd.2016.01.008  0.389
2016 Broxmeyer HE, Capitano M, Campbell TB, Hangoc G, Cooper S. Modulation of Hematopoietic Chemokine Effects In Vitro and In Vivo by DPP4/CD26. Stem Cells and Development. PMID 26943017 DOI: 10.1089/Scd.2016.0026  0.453
2016 Huang X, Guo B, Broxmeyer HE. Inhibition of HDAC5-Mediated p65 Deacetylation Enhances Human Cord Blood Hematopoietic Stem Cell Homing and Engraftment in NSG Mice Blood. 128: 884-884. DOI: 10.1182/Blood.V128.22.884.884  0.462
2016 Broxmeyer HE, Capitano ML, O'leary HA, Cooper S, Chua HL, Plett A, Orschell CM. Re-Evaluation of Age-Related Dysregulation of Hematopoiesis Based on Oxygen Induced Changes Associated with Cell Collection/Processing in Ambient Air Blood. 128: 5051-5051. DOI: 10.1182/Blood.V128.22.5051.5051  0.439
2016 Guo B, Huang X, Cooper S, Broxmeyer HE. Human Hematopoietic Stem Cell Homing and Engraftment Promoted By Glucocorticoid Induced Chromatin Remodeling Blood. 128: 494-494. DOI: 10.1182/Blood.V128.22.494.494  0.452
2016 Capitano ML, Mor-Vaknin N, Legendre M, Cooper S, Markovitz D, Broxmeyer HE. DEK Regulates Hematopoietic Stem and Progenitor Cell Fate By Activating AKT and ERK Mediated Signaling through CXCR2/Heparan Sulfate Proteoglycans Blood. 128: 2645-2645. DOI: 10.1182/Blood.V128.22.2645.2645  0.509
2016 Kim JA, Kwak J, Eunjung Y, Lee J, Park Y, Broxmeyer HE. Fractalkine/CX3CR1 Signaling Promotes Angiogenic Potentials in CX3CR1 Expressing Monocytes Blood. 128: 2507-2507. DOI: 10.1182/Blood.V128.22.2507.2507  0.408
2016 Ramadan A, Zhang J, Zaid MA, Taylor L, O'Leary H, Kapur R, Hanenberg H, Broxmeyer H, Kaplan M, Paczesny S. Id: 95: Il-33/St2 Triggering Of Il-9–Secreting T Cells: From Proteomics To Therapeutics Journal of Investigative Medicine. 64: 948-948. DOI: 10.1136/Jim-2016-000120.73  0.497
2016 Ramadan A, Zhang J, Zaid MA, Taylor L, O'Leary HA, Kapur R, Hanenberg H, Broxmeyer HE, Kaplan MH, Paczesny S. 508. IL-33/ST2 Triggering of IL-9-Secreting T Cells: From Proteomics to Therapeutics Molecular Therapy. 24: S202-S203. DOI: 10.1016/S1525-0016(16)33317-2  0.497
2016 O'Leary H, Jiang G, Lai X, McNamara T, Li S, Mantel C, Cooper S, Hangoc G, Lee M, Boswell HS, Witzmann F, Li L, Broxmeyer H. Dipeptidyl peptidase 4 (DPP4) truncated factors manifest distinct regulatory functions compared to their full length forms and DPP4 is altered by, and modulates stem cell response to, extra physiologic oxygen shock/stress (EPHOSS) Experimental Hematology. 44. DOI: 10.1016/J.Exphem.2016.06.198  0.369
2015 Lakhter AJ, Lahm T, Broxmeyer HE, Naidu SR. Golgi Associated HIF1a Serves as a Reserve in Melanoma Cells. Journal of Cellular Biochemistry. PMID 26375488 DOI: 10.1002/Jcb.25381  0.342
2015 Huang X, Lee MR, Cooper S, Hangoc G, Hong KS, Chung HM, Broxmeyer HE. Activation of OCT4 enhances ex vivo expansion of human cord blood hematopoietic stem and progenitor cells by regulating HOXB4 expression. Leukemia. PMID 26202933 DOI: 10.1038/Leu.2015.189  0.558
2015 Mantel CR, O'Leary HA, Chitteti BR, Huang X, Cooper S, Hangoc G, Brustovetsky N, Srour EF, Lee MR, Messina-Graham S, Haas DM, Falah N, Kapur R, Pelus LM, Bardeesy N, ... ... Broxmeyer HE, et al. Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock. Cell. 161: 1553-65. PMID 26073944 DOI: 10.1016/J.Cell.2015.04.054  0.441
2015 Broxmeyer HE, O'Leary HA, Huang X, Mantel C. The importance of hypoxia and extra physiologic oxygen shock/stress for collection and processing of stem and progenitor cells to understand true physiology/pathology of these cells ex vivo. Current Opinion in Hematology. 22: 273-8. PMID 26049746 DOI: 10.1097/Moh.0000000000000144  0.402
2015 Capitano ML, Chitteti BR, Cooper S, Srour EF, Bartke A, Broxmeyer HE. Ames hypopituitary dwarf mice demonstrate imbalanced myelopoiesis between bone marrow and spleen. Blood Cells, Molecules & Diseases. 55: 15-20. PMID 25976461 DOI: 10.1016/J.Bcmd.2015.03.004  0.396
2015 Liu Y, Huang X, Timani KA, Broxmeyer HE, He JJ. microRNA-124 Targets Tip110 Expression and Regulates Hematopoiesis. Stem Cells and Development. PMID 25928721 DOI: 10.1089/Scd.2015.0030  0.379
2015 Wang L, Zoetemelk M, Chitteti BR, Ratliff TL, Myers JD, Srour EF, Broxmeyer H, Jerde TJ. Expansion of prostate epithelial progenitor cells after inflammation of the mouse prostate. American Journal of Physiology. Renal Physiology. 308: F1421-30. PMID 25925259 DOI: 10.1152/Ajprenal.00488.2014  0.314
2015 Capitano ML, Hangoc G, Cooper S, Broxmeyer HE. Mild Heat Treatment Primes Human CD34(+) Cord Blood Cells for Migration Toward SDF-1α and Enhances Engraftment in an NSG Mouse Model. Stem Cells (Dayton, Ohio). 33: 1975-84. PMID 25753525 DOI: 10.1002/Stem.1988  0.419
2015 Zeng Y, Broxmeyer HE, Staser K, Chitteti BR, Park SJ, Hahn S, Cooper S, Sun Z, Jiang L, Yang X, Yuan J, Kosoff R, Sandusky G, Srour EF, Chernoff J, et al. Pak2 regulates hematopoietic progenitor cell proliferation, survival, and differentiation. Stem Cells (Dayton, Ohio). 33: 1630-41. PMID 25586960 DOI: 10.1002/Stem.1951  0.525
2015 Thangamani S, Kim M, Son Y, Huang X, Kim H, Lee JH, Cho J, Ulrich B, Broxmeyer HE, Kim CH. Cutting edge: progesterone directly upregulates vitamin d receptor gene expression for efficient regulation of T cells by calcitriol. Journal of Immunology (Baltimore, Md. : 1950). 194: 883-6. PMID 25548222 DOI: 10.4049/Jimmunol.1401923  0.372
2015 Xie J, Broxmeyer HE, Feng D, Schweitzer KS, Yi R, Cook TG, Chitteti BR, Barwinska D, Traktuev DO, Van Demark MJ, Justice MJ, Ou X, Srour EF, Prockop DJ, Petrache I, et al. Human adipose-derived stem cells ameliorate cigarette smoke-induced murine myelosuppression via secretion of TSG-6. Stem Cells (Dayton, Ohio). 33: 468-78. PMID 25329668 DOI: 10.1002/Stem.1851  0.637
2015 Broxmeyer HE, Capitano ML, Zhao L, Cooper S, Abrams CS. Role for Megakaryocyte Phosphatidylinositol Transfer Proteins-Alpha and -Beta in TGF Beta-Mediated Regulation of Hematopoietic Homeostasis Blood. 126: 780-780. DOI: 10.1182/Blood.V126.23.780.780  0.382
2015 Capitano ML, Mor-Vaknin N, Legendre M, Cooper S, Markovitz D, Broxmeyer HE. Recombinant DEK Enhances Ex Vivo expansion of Human Cord Blood and Mouse Bone Marrow Hematopoietic Stem Cells in a CXCR2- and Hspg-Dependent Manner Blood. 126: 779-779. DOI: 10.1182/Blood.V126.23.779.779  0.535
2015 Messina-Graham S, Broxmeyer HE. SDF-1/CXCL12 Modulates Mitochondrial Respiration of Hematopoietic Stem and Progenitor Cells in a Bi-Phasic Manner Blood. 126: 2389-2389. DOI: 10.1182/Blood.V126.23.2389.2389  0.413
2015 O'Leary HA, McNamara T, Broxmeyer HE. Dipeptidyl Peptidase 4 (DPP4) Is Altered By, and Modulates Sensitivity to, Extra-Physiologic Oxygen Shock Stress (EPHOSS): Implications for Hematopoietic Stem Cell Transplantation Blood. 126: 2361-2361. DOI: 10.1182/Blood.V126.23.2361.2361  0.504
2015 Ramadan A, Zhang J, Abu Zaid M, O'Leary H, Kapur R, Hanenberg H, Sun J, Broxmeyer HE, Kaplan MH, Paczesny S. IL-33/ST2 Triggering of IL-9-Secreting T Cells Alters the Balance of Fatal Immunity and Tumor Immunity Blood. 126: 231-231. DOI: 10.1182/Blood.V126.23.231.231  0.482
2015 Aljitawi OS, Lin TL, Vielhauer G, Cheung A, Capitano ML, Li D, Wise A, Lipe BC, Paul S, Laughlin M, Broxmeyer HE. Impact of Erythropoietin Modulation Using Hyperbaric Oxygen on Umbilical Cord Blood CD34+ Cell Homing Blood. 126: 1870-1870. DOI: 10.1182/Blood.V126.23.1870.1870  0.453
2015 Wang L, Srour E, Zhang J, Broxmeyer H, Jerde T. MP19-20 SURVIVIN MEDIATES INFLAMMATION-DRIVEN EXPANSION OF PROGENITOR CELLS IN THE PROSTATE Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.1012  0.327
2014 Prasain N, Lee MR, Vemula S, Meador JL, Yoshimoto M, Ferkowicz MJ, Fett A, Gupta M, Rapp BM, Saadatzadeh MR, Ginsberg M, Elemento O, Lee Y, Voytik-Harbin SL, Chung HM, ... ... Broxmeyer HE, et al. Differentiation of human pluripotent stem cells to cells similar to cord-blood endothelial colony-forming cells. Nature Biotechnology. 32: 1151-7. PMID 25306246 DOI: 10.1038/Nbt.3048  0.506
2014 Hwang S, Lee SJ, Park SH, Chitteti BR, Srour EF, Cooper S, Hangoc G, Broxmeyer HE, Kwon BS. Nonmarrow hematopoiesis occurs in a hyaluronic-acid-rich node and duct system in mice. Stem Cells and Development. 23: 2661-71. PMID 24914588 DOI: 10.1089/Scd.2014.0075  0.499
2014 Broxmeyer HE. Inhibiting HDAC for human hematopoietic stem cell expansion. The Journal of Clinical Investigation. 124: 2365-8. PMID 24892711 DOI: 10.1172/Jci75803  0.429
2014 Chitteti BR, Kobayashi M, Cheng Y, Zhang H, Poteat BA, Broxmeyer HE, Pelus LM, Hanenberg H, Zollman A, Kamocka MM, Carlesso N, Cardoso AA, Kacena MA, Srour EF. CD166 regulates human and murine hematopoietic stem cells and the hematopoietic niche. Blood. 124: 519-29. PMID 24740813 DOI: 10.1182/Blood-2014-03-565721  0.384
2014 Broxmeyer HE, Pelus LM. Inhibition of DPP4/CD26 and dmPGE₂ treatment enhances engraftment of mouse bone marrow hematopoietic stem cells. Blood Cells, Molecules & Diseases. 53: 34-8. PMID 24602918 DOI: 10.1016/J.Bcmd.2014.02.002  0.518
2014 Ou X, Lee MR, Huang X, Messina-Graham S, Broxmeyer HE. SIRT1 positively regulates autophagy and mitochondria function in embryonic stem cells under oxidative stress. Stem Cells (Dayton, Ohio). 32: 1183-94. PMID 24449278 DOI: 10.1002/Stem.1641  0.587
2014 Vélez de Mendizábal N, Strother RM, Farag SS, Broxmeyer HE, Messina-Graham S, Chitnis SD, Bies RR. Modelling the sitagliptin effect on dipeptidyl peptidase-4 activity in adults with haematological malignancies after umbilical cord blood haematopoietic cell transplantation. Clinical Pharmacokinetics. 53: 247-59. PMID 24142388 DOI: 10.1007/S40262-013-0109-Y  0.405
2014 Aljitawi OS, Xiao Y, Eskew JD, Parelkar NK, Swink M, Radel J, Lin TL, Kimler BF, Mahnken JD, McGuirk JP, Broxmeyer HE, Vielhauer G. Hyperbaric oxygen improves engraftment of ex-vivo expanded and gene transduced human CD34⁺ cells in a murine model of umbilical cord blood transplantation. Blood Cells, Molecules & Diseases. 52: 59-67. PMID 23953010 DOI: 10.1016/J.Bcmd.2013.07.013  0.436
2014 Huang X, Cooper S, Broxmeyer HE. Activation of OCT4 Enhances Ex Vivo Expansion of Phenotypically Defined and Functionally Engraftable Human Cord Blood Hematopoietic Stem and Progenitor Cells By Regulating HOXB4 Expression Blood. 124: 4332-4332. DOI: 10.1182/Blood.V124.21.4332.4332  0.521
2014 O'Leary HA, Mantel C, Lee MR, Lai X, Cooper S, Hangoc G, Boswell HS, Broxmeyer HE. Unique and Unexpected Functional Activities of Hematopoietically Active Cytokines Truncated By Dipeptidylpeptidase-4 (DPP4) Blood. 124: 2922-2922. DOI: 10.1182/Blood.V124.21.2922.2922  0.378
2014 Mantel C, O'Leary HA, Chitteti BR, Huang X, Cooper S, Hangoc G, Brustovetsky N, Srour EF, Lee MR, Messina-Graham S, Falah N, Kapur R, Pelus LM, Ivan M, Kim K, ... Broxmeyer HE, et al. Mitigation of a Newly Discovered Phenomenon, Extra Physiologic Oxygen Shock/Stress (EPHOSS), Mediated By the Mitochondria Permeability Transition Pore, Greatly Improves Stem Cell Collection and Transplantation Blood. 124: 2905-2905. DOI: 10.1182/Blood.V124.21.2905.2905  0.475
2014 Capitano ML, Mor-Vaknin N, Legendre M, Markovitz D, Broxmeyer HE. Extracellular DEK Is a Novel Chemotactic Agent of Lineage Negative, Sca-1 Positive, c-Kit Positive Bone Marrow Cells Blood. 124: 1583-1583. DOI: 10.1182/Blood.V124.21.1583.1583  0.493
2014 Capitano ML, Mor-Vaknin N, Legendre M, Cooper S, Markovitz D, Broxmeyer HE. Recombinant DEK Regulates Hematopoietic Stem and Progenitor Cells in a CXCR2- GαI Protein-Dependent Manner Blood. 124: 1582-1582. DOI: 10.1182/Blood.V124.21.1582.1582  0.527
2014 Kim J, Kwak J, Noh K, Lee J, Park Y, Broxmeyer HE. The Role of CD11b+CX3CR1+ Cells in Neovascularization Blood. 124: 4180-4180. DOI: 10.1182/Blood.V122.21.2301.2301  0.46
2014 O'Leary H, Mantel C, Lee MR, Lai X, Cooper S, Hangoc G, Boswell HS, Broxmeyer H. DPP4 truncation alters the signaling and functional activity of GM-CSF and LL-3 in normal and leukemic hematopoietic cells Experimental Hematology. 42. DOI: 10.1016/J.Exphem.2014.07.206  0.422
2014 Capitano M, Mor-Vaknin N, Legendre M, Cooper S, Broxmeyer H. Recombinant DEK regulates hematopoietic stem and progenitor cells in vivo Experimental Hematology. 42: S28. DOI: 10.1016/J.Exphem.2014.07.097  0.475
2014 Capitano M, Hangoc G, Broxmeyer H. Mild heating of human CD34+ cord blood cells increases lipid raft aggregation resulting in an earlier engraftment in NSG mice following transplantation Experimental Hematology. 42: S27. DOI: 10.1016/J.Exphem.2014.07.096  0.4
2014 Broxmeyer H, Cooper S, Campbell T, O'Leary H, Hangoc G. DPP4 regulates in vitro and in vivo hematopoiesis mediated by myelosuppressive chemokines Experimental Hematology. 42. DOI: 10.1016/J.Exphem.2014.07.088  0.364
2013 Broxmeyer HE. Counteracting the enzymatic activity of dipeptidylpeptidase 4 for potential therapeutic advantage, with an emphasis on cord blood transplantation. The Korean Journal of Internal Medicine. 28: 639-45. PMID 24307836 DOI: 10.3904/Kjim.2013.28.6.639  0.435
2013 Broxmeyer HE, Farag S. Background and future considerations for human cord blood hematopoietic cell transplantation, including economic concerns. Stem Cells and Development. 22: 103-10. PMID 24304086 DOI: 10.1089/Scd.2013.0382  0.461
2013 Lee JH, Hong KS, Mantel C, Broxmeyer HE, Lee MR, Kim KS. Spontaneously differentiated GATA6-positive human embryonic stem cells represent an important cellular step in human embryonic development; they are not just an artifact of in vitro culture. Stem Cells and Development. 22: 2706-13. PMID 23746070 DOI: 10.1089/Scd.2013.0083  0.462
2013 Broxmeyer HE, Mor-Vaknin N, Kappes F, Legendre M, Saha AK, Ou X, O'Leary H, Capitano M, Cooper S, Markovitz DM. Concise review: role of DEK in stem/progenitor cell biology. Stem Cells (Dayton, Ohio). 31: 1447-53. PMID 23733396 DOI: 10.1002/Stem.1443  0.684
2013 Ballen KK, Gluckman E, Broxmeyer HE. Umbilical cord blood transplantation: the first 25 years and beyond. Blood. 122: 491-8. PMID 23673863 DOI: 10.1182/Blood-2013-02-453175  0.368
2013 Ou X, O'Leary HA, Broxmeyer HE. Implications of DPP4 modification of proteins that regulate stem/progenitor and more mature cell types. Blood. 122: 161-9. PMID 23637126 DOI: 10.1182/Blood-2013-02-487470  0.687
2013 Zhao W, Breese E, Bowers A, Hoggatt J, Pelus LM, Broxmeyer HE, Goebl M, Harrington MA. SIMPL enhancement of tumor necrosis factor-α dependent p65-MED1 complex formation is required for mammalian hematopoietic stem and progenitor cell function. Plos One. 8: e61123. PMID 23630580 DOI: 10.1371/Journal.Pone.0061123  0.36
2013 O'Leary H, Ou X, Broxmeyer HE. The role of dipeptidyl peptidase 4 in hematopoiesis and transplantation. Current Opinion in Hematology. 20: 314-9. PMID 23594692 DOI: 10.1097/Moh.0B013E32836125Ac  0.663
2013 Broxmeyer HE. Erythropoietin: multiple targets, actions, and modifying influences for biological and clinical consideration. The Journal of Experimental Medicine. 210: 205-8. PMID 23401569 DOI: 10.1084/Jem.20122760  0.425
2013 Basu S, Broxmeyer HE, Hangoc G. Peroxisome proliferator-activated-γ coactivator-1α-mediated mitochondrial biogenesis is important for hematopoietic recovery in response to stress. Stem Cells and Development. 22: 1678-92. PMID 23311338 DOI: 10.1089/Scd.2012.0466  0.404
2013 Yu WM, Liu X, Shen J, Jovanovic O, Pohl EE, Gerson SL, Finkel T, Broxmeyer HE, Qu CK. Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation. Cell Stem Cell. 12: 62-74. PMID 23290137 DOI: 10.1016/J.Stem.2012.11.022  0.407
2013 Farag SS, Srivastava S, Messina-Graham S, Schwartz J, Robertson MJ, Abonour R, Cornetta K, Wood L, Secrest A, Strother RM, Jones DR, Broxmeyer HE. In vivo DPP-4 inhibition to enhance engraftment of single-unit cord blood transplants in adults with hematological malignancies. Stem Cells and Development. 22: 1007-15. PMID 23270493 DOI: 10.1089/Scd.2012.0636  0.385
2013 Lee MR, Prasain N, Chae HD, Kim YJ, Mantel C, Yoder MC, Broxmeyer HE. Epigenetic regulation of NANOG by miR-302 cluster-MBD2 completes induced pluripotent stem cell reprogramming. Stem Cells (Dayton, Ohio). 31: 666-81. PMID 23255147 DOI: 10.1002/Stem.1302  0.395
2013 Liu Y, Timani K, Ou X, Broxmeyer HE, He JJ. C-MYC controlled TIP110 protein expression regulates OCT4 mRNA splicing in human embryonic stem cells. Stem Cells and Development. 22: 689-94. PMID 23088399 DOI: 10.1089/Scd.2012.0271  0.629
2013 Broxmeyer HE, Etienne-Julan M, Gotoh A, Braun SE, Lu L, Cooper S, Feng GS, Li XJ, Chan RJ. Hematopoietic colony formation from human growth factor-dependent TF1 cells and human cord blood myeloid progenitor cells depends on SHP2 phosphatase function. Stem Cells and Development. 22: 998-1006. PMID 23082805 DOI: 10.1089/Scd.2012.0478  0.462
2013 Capitano ML, Hangoc G, Broxmeyer HE. Mild Hyperthermia Treatment Of CD34+ Human Cord Blood Cells Increases Lipid Raft Aggregation Resulting In An Earlier Engraftment In NSG Mice Following Transplantation Blood. 122: 3241-3241. DOI: 10.1182/Blood.V122.21.3241.3241  0.461
2013 Kim J, Kwak J, Noh K, Kim H, Lee B, Park Y, Kim YJ, Broxmeyer HE. The Role Of CD11b+CX3CR1+ Cells In Neovascularization Blood. 122: 2301-2301. DOI: 10.1182/blood.V122.21.2301.2301  0.308
2013 O'Leary HA, Mantel C, Lai X, Cooper S, Hangoc G, Boswell HS, Witzmann F, Broxmeyer HE. DPP4 (CD26) Truncation Of GM-CSF and IL-3 Alters Their Signaling and Functional Activity In Normal and Leukemic Hematopoietic Stem and Progenitor Cells Blood. 122: 1206-1206. DOI: 10.1182/Blood.V122.21.1206.1206  0.517
2013 Broxmeyer HE. Update on "Stem and Progenitor Cells Isolated from Cord Blood" Handbook of Stem Cells. 2: 477-480. DOI: 10.1016/B978-0-12-385942-6.00041-X  0.304
2012 Broxmeyer HE, Hoggatt J, O'Leary HA, Mantel C, Chitteti BR, Cooper S, Messina-Graham S, Hangoc G, Farag S, Rohrabaugh SL, Ou X, Speth J, Pelus LM, Srour EF, Campbell TB. Dipeptidylpeptidase 4 negatively regulates colony-stimulating factor activity and stress hematopoiesis. Nature Medicine. 18: 1786-96. PMID 23160239 DOI: 10.1038/Nm.2991  0.828
2012 Sawant DV, Sehra S, Nguyen ET, Jadhav R, Englert K, Shinnakasu R, Hangoc G, Broxmeyer HE, Nakayama T, Perumal NB, Kaplan MH, Dent AL. Bcl6 controls the Th2 inflammatory activity of regulatory T cells by repressing Gata3 function. Journal of Immunology (Baltimore, Md. : 1950). 189: 4759-69. PMID 23053511 DOI: 10.4049/Jimmunol.1201794  0.372
2012 Broxmeyer HE, Mantel C. A ROSy future for metabolic regulation of HSC division. Nature Medicine. 18: 1334-6. PMID 22961159 DOI: 10.1038/Nm.2917  0.431
2012 Broxmeyer HE. Enhancing engraftment of cord blood cells via insight into the biology of stem/progenitor cell function. Annals of the New York Academy of Sciences. 1266: 151-60. PMID 22901266 DOI: 10.1111/J.1749-6632.2012.06509.X  0.49
2012 Jin HL, Kim JS, Kim YJ, Kim SJ, Broxmeyer HE, Kim KS. Dynamic expression of specific miRNAs during erythroid differentiation of human embryonic stem cells. Molecules and Cells. 34: 177-83. PMID 22767248 DOI: 10.1007/S10059-012-0090-6  0.39
2012 Mantel C, Messina-Graham S, Moh A, Cooper S, Hangoc G, Fu XY, Broxmeyer HE. Mouse hematopoietic cell-targeted STAT3 deletion: stem/progenitor cell defects, mitochondrial dysfunction, ROS overproduction, and a rapid aging-like phenotype. Blood. 120: 2589-99. PMID 22665934 DOI: 10.1182/Blood-2012-01-404004  0.394
2012 Broxmeyer HE, Christopherson K, Hangoc G, Cooper S, Mantel C, Renukaradhya GJ, Brutkiewicz RR. CD1d expression on and regulation of murine hematopoietic stem and progenitor cells. Blood. 119: 5731-41. PMID 22535665 DOI: 10.1182/Blood-2012-01-404012  0.542
2012 Liu Y, Lee MR, Timani K, He JJ, Broxmeyer HE. Tip110 maintains expression of pluripotent factors in and pluripotency of human embryonic stem cells. Stem Cells and Development. 21: 829-33. PMID 22132941 DOI: 10.1182/Blood.V118.21.2353.2353  0.396
2012 Chae HD, Lee MR, Broxmeyer HE. 5-Aminoimidazole-4-carboxyamide ribonucleoside induces G(1)/S arrest and Nanog downregulation via p53 and enhances erythroid differentiation. Stem Cells (Dayton, Ohio). 30: 140-9. PMID 22076938 DOI: 10.1002/Stem.778  0.443
2012 Broxmeyer HE, Srour EF, Cooper S, Wallace CT, Hangoc G, Youn BS. Angiopoietin-like-2 and -3 act through their coiled-coil domains to enhance survival and replating capacity of human cord blood hematopoietic progenitors. Blood Cells, Molecules & Diseases. 48: 25-9. PMID 21983347 DOI: 10.1016/J.Bcmd.2011.09.004  0.468
2012 Broxmeyer HE, Kappes F, Mor-Vaknin N, Legendre M, Kinzfogl J, Cooper S, Hangoc G, Markovitz DM. DEK regulates hematopoietic stem engraftment and progenitor cell proliferation. Stem Cells and Development. 21: 1449-54. PMID 21943234 DOI: 10.1182/Blood.V118.21.1275.1275  0.848
2012 Broxmeyer HE, Franklin DS, Cooper S, Hangoc G, Mantel C. Cyclin dependent kinase inhibitors differentially modulate synergistic cytokine responsiveness of hematopoietic progenitor cells. Stem Cells and Development. 21: 1597-603. PMID 21936707 DOI: 10.1089/Scd.2011.0476  0.429
2012 Yu W, Liu X, Shen J, Jovanovic O, Pohl EE, Gerson SL, Finkel T, Broxmeyer HE, Qu C. Disruption of Mitochondrial Phosphatase Ptpmt1 Induces Bioenergetic Stress and Differentiation Block in Hematopoietic Stem Cells Blood. 120: 857-857. DOI: 10.1182/Blood.V120.21.857.857  0.49
2012 Chitteti BR, Kobayashi M, Cheng Y, Hu P, Poteat B, Broxmeyer HE, Pelus LM, Kacena MA, Srour EF. CD166 (ALCAM): A Functional Marker of Primitive Murine and Human Hematopoietic Stem Cells and Cellular Elements of Their Niche Blood. 120: 640-640. DOI: 10.1182/Blood.V120.21.640.640  0.426
2012 Ou X, Broxmeyer HE. CD26/Dipeptidylpeptidase IV Negatively Regulates Leukemia Inhibitory Factory Activity in Murine Embryonic Stem Cells Blood. 120: 4741-4741. DOI: 10.1182/Blood.V120.21.4741.4741  0.713
2012 O'Leary HA, Mantel C, Cooper S, Walker CJ, Broxmeyer HE. CD26 Truncation of GM-CSF and IL-3 Alters Their Functional Interactions Blood. 120: 1240-1240. DOI: 10.1182/Blood.V120.21.1240.1240  0.418
2012 Zoetemelk M, Myers J, Srour E, Broxmeyer H, Wang L, Jerde T. 1577 INFLAMMATION EXPANDS PUTATIVE PROGENITOR CELLS IN HYPERPLASTIC PROSTATES Journal of Urology. 187. DOI: 10.1016/J.Juro.2012.02.1349  0.365
2012 Broxmeyer HE. Preclinical experience with amd3100 for mobilization of hematopoietic stem and progenitor cells Novel Developments in Stem Cell Mobilization: Focus On Cxcr4. 3-22. DOI: 10.1007/978-1-4614-1960-0_1  0.379
2011 Kim YJ, Park SJ, Broxmeyer HE. Phagocytosis, a potential mechanism for myeloid-derived suppressor cell regulation of CD8+ T cell function mediated through programmed cell death-1 and programmed cell death-1 ligand interaction. Journal of Immunology (Baltimore, Md. : 1950). 187: 2291-301. PMID 21795591 DOI: 10.4049/Jimmunol.1002650  0.422
2011 Kinzfogl J, Hangoc G, Broxmeyer HE. Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells. Blood. 118: 565-75. PMID 21628410 DOI: 10.1182/Blood-2010-12-325381  0.823
2011 Mantel C, Messina-Graham SV, Broxmeyer HE. Superoxide flashes, reactive oxygen species, and the mitochondrial permeability transition pore: potential implications for hematopoietic stem cell function. Current Opinion in Hematology. 18: 208-13. PMID 21537169 DOI: 10.1097/Moh.0B013E3283475Ffe  0.37
2011 Kaplan MH, Glosson NL, Stritesky GL, Yeh N, Kinzfogl J, Rohrabaugh SL, Goswami R, Pham D, Levy DE, Brutkiewicz RR, Blum JS, Cooper S, Hangoc G, Broxmeyer HE. STAT3-dependent IL-21 production from T helper cells regulates hematopoietic progenitor cell homeostasis. Blood. 117: 6198-201. PMID 21505191 DOI: 10.1182/Blood-2011-02-334367  0.79
2011 Dar A, Schajnovitz A, Lapid K, Kalinkovich A, Itkin T, Ludin A, Kao WM, Battista M, Tesio M, Kollet O, Cohen NN, Margalit R, Buss EC, Baleux F, Oishi S, ... ... Broxmeyer HE, et al. Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells. Leukemia. 25: 1286-96. PMID 21494253 DOI: 10.1038/Leu.2011.62  0.453
2011 Broxmeyer HE. Insights into the biology of cord blood stem/progenitor cells Cell Proliferation. 44: 55-59. PMID 21481045 DOI: 10.1111/j.1365-2184.2010.00728.x  0.319
2011 Liu Y, Timani K, Mantel C, Fan Y, Hangoc G, Cooper S, He JJ, Broxmeyer HE. TIP110/p110nrb/SART3/p110 regulation of hematopoiesis through CMYC. Blood. 117: 5643-51. PMID 21447833 DOI: 10.1182/Blood-2010-12-325332  0.466
2011 Rohrabaugh SL, Campbell TB, Hangoc G, Broxmeyer HE. Ex vivo rapamycin treatment of human cord blood CD34+ cells enhances their engraftment of NSG mice. Blood Cells, Molecules & Diseases. 46: 318-20. PMID 21411351 DOI: 10.1016/J.Bcmd.2011.02.006  0.837
2011 Broxmeyer HE, Lee MR, Hangoc G, Cooper S, Prasain N, Kim YJ, Mallett C, Ye Z, Witting S, Cornetta K, Cheng L, Yoder MC. Hematopoietic stem/progenitor cells, generation of induced pluripotent stem cells, and isolation of endothelial progenitors from 21- to 23.5-year cryopreserved cord blood. Blood. 117: 4773-7. PMID 21393480 DOI: 10.1182/Blood-2011-01-330514  0.53
2011 Broxmeyer HE. Erythropoietin surprises: an immune saga. Immunity. 34: 6-7. PMID 21272782 DOI: 10.1016/J.Immuni.2011.01.004  0.344
2011 Rohrabaugh SL, Hangoc G, Kelley MR, Broxmeyer HE. Mad2 haploinsufficiency protects hematopoietic progenitor cells subjected to cell-cycle stress in vivo and to inhibition of redox function of Ape1/Ref-1 in vitro. Experimental Hematology. 39: 415-23. PMID 21216274 DOI: 10.1016/J.Exphem.2010.12.012  0.815
2011 Chae HD, Broxmeyer HE. SIRT1 deficiency downregulates PTEN/JNK/FOXO1 pathway to block reactive oxygen species-induced apoptosis in mouse embryonic stem cells. Stem Cells and Development. 20: 1277-85. PMID 21083429 DOI: 10.1089/Scd.2010.0465  0.376
2011 Ou X, Chae HD, Wang RH, Shelley WC, Cooper S, Taylor T, Kim YJ, Deng CX, Yoder MC, Broxmeyer HE. SIRT1 deficiency compromises mouse embryonic stem cell hematopoietic differentiation, and embryonic and adult hematopoiesis in the mouse. Blood. 117: 440-50. PMID 20966168 DOI: 10.1182/Blood-2010-03-273011  0.773
2011 Kim YJ, Broxmeyer HE. Immune regulatory cells in umbilical cord blood and their potential roles in transplantation tolerance. Critical Reviews in Oncology/Hematology. 79: 112-26. PMID 20727784 DOI: 10.1016/J.Critrevonc.2010.07.009  0.464
2011 Schweitzer KS, Johnstone BH, Garrison J, Rush NI, Cooper S, Traktuev DO, Feng D, Adamowicz JJ, Van Demark M, Fisher AJ, Kamocki K, Brown MB, Presson RG, Broxmeyer HE, March KL, et al. Adipose stem cell treatment in mice attenuates lung and systemic injury induced by cigarette smoking. American Journal of Respiratory and Critical Care Medicine. 183: 215-25. PMID 20709815 DOI: 10.1164/Rccm.201001-0126Oc  0.404
2011 Kim J, Noh K, Kim H, Broxmeyer HE. CCR2 and CCR5 Co-Expressing CD11b+ Monocytes Affect Neovascularization in An Ischemic Hind Limb Mouse Model, Blood. 118: 3270-3270. DOI: 10.1182/Blood.V118.21.3270.3270  0.348
2011 Lee MR, Prasain N, Kim Y, Yoder MC, Broxmeyer HE. Mir-302 Cluster Governs Complete Nuclear Reprogramming Through Suppression of MBD2 in iPSCs Derived From CD34+ Cord Blood Cells Stored Frozen for More Than 20 Years Blood. 118: 1265-1265. DOI: 10.1182/Blood.V118.21.1265.1265  0.373
2011 Dar A, Schajnovitz A, Lapid K, Kalinkovich A, Itkin T, Ludin A, Kao WM, Battista M, Tesio M, Kollet O, Cohen NN, Margalit R, Buss EC, Baleux F, Oishi S, ... ... Broxmeyer HE, et al. Erratum: Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells (Leukemia (April 2011) DOI:10.1038/leu.2011.62) Leukemia. 25. DOI: 10.1038/Leu.2011.132  0.397
2010 Ha SP, Klemen ND, Kinnebrew GH, Brandmaier AG, Marsh J, Hangoc G, Palmer DC, Restifo NP, Cornetta K, Broxmeyer HE, Touloukian CE. Transplantation of mouse HSCs genetically modified to express a CD4-restricted TCR results in long-term immunity that destroys tumors and initiates spontaneous autoimmunity. The Journal of Clinical Investigation. 120: 4273-88. PMID 21084750 DOI: 10.1172/Jci43274  0.405
2010 Kim JA, March K, Chae HD, Johnstone B, Park SJ, Cook T, Merfeld-Clauss S, Broxmeyer HE. Muscle-derived Gr1(dim)CD11b(+) cells enhance neovascularization in an ischemic hind limb mouse model. Blood. 116: 1623-6. PMID 20516368 DOI: 10.1182/Blood-2009-08-237040  0.398
2010 Mantel C, Messina-Graham S, Broxmeyer HE. Upregulation of nascent mitochondrial biogenesis in mouse hematopoietic stem cells parallels upregulation of CD34 and loss of pluripotency: a potential strategy for reducing oxidative risk in stem cells. Cell Cycle (Georgetown, Tex.). 9: 2008-17. PMID 20495374 DOI: 10.4161/Cc.9.10.11733  0.445
2010 Taylor T, Kim YJ, Ou X, Derbigny W, Broxmeyer HE. Toll-like receptor 2 mediates proliferation, survival, NF-kappaB translocation, and cytokine mRNA expression in LIF-maintained mouse embryonic stem cells. Stem Cells and Development. 19: 1333-41. PMID 20132051 DOI: 10.1089/Scd.2009.0484  0.723
2010 Broxmeyer HE. Umbilical cord transplantation: epilogue. Seminars in Hematology. 47: 97-103. PMID 20109617 DOI: 10.1053/J.Seminhematol.2009.10.002  0.446
2010 Broxmeyer HE. Will iPS cells enhance therapeutic applicability of cord blood cells and banking? Cell Stem Cell. 6: 21-4. PMID 20074533 DOI: 10.1016/J.Stem.2009.12.008  0.489
2010 Rocha V, Broxmeyer HE. New approaches for improving engraftment after cord blood transplantation. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 16: S126-32. PMID 19896543 DOI: 10.1016/J.Bbmt.2009.11.001  0.413
2010 Kinzfogl J, Hangoc G, Broxmeyer HE. The Neurexin I Alpha/Neurexophilin Axis as An Anti-Proliferative Factor In Human Cord Blood and Murine Bone Marrow Hematopoiesis. Blood. 116: 2627-2627. DOI: 10.1182/Blood.V116.21.2627.2627  0.845
2010 Lee MR, Prasain N, Kim Y, Yoder MC, Broxmeyer HE. Human Embryonic Stem Cell-Specific Micrornas Promote Full Programming of Induced Pluripotent Stem Cells Derived From CD34+ Cord Blood Cells Stored Frozen for More Than 20 Years. Blood. 116: 2622-2622. DOI: 10.1182/Blood.V116.21.2622.2622  0.483
2010 Mantel C, Messina-Graham S, Moh A, Fu X, Broxmeyer HE. STAT3 Deletion In Hematopoietic Tissue Causes Mitochondrial Dysfunction with Increased ROS Leading to LT-Repopulating Stem Cell Depletion, Erythroid Dysplasia, Peripheral Neutrophilia, and a Rapid Aging-Like Phenotype. Blood. 116: 2621-2621. DOI: 10.1182/Blood.V116.21.2621.2621  0.481
2010 Ou X, Chae H, Wang R, Shelley WC, Cooper S, Taylor T, Kim Y, Deng C, Yoder MC, Broxmeyer HE. SIRT1 Deficiency Compromises Mouse Embryonic Stem Cell Differentiation, and Embryonic and Adult Hematopoiesis In the Mouse. Blood. 116: 1612-1612. DOI: 10.1182/Blood.V116.21.1612.1612  0.782
2010 Chae H, Broxmeyer HE. SIRT1 Regulates PTEN/Akt/FOXO1 Pathway to Trigger ROS-Induced Apoptosis In Mouse Embryonic Stem Cells. Blood. 116: 1610-1610. DOI: 10.1182/Blood.V116.21.1610.1610  0.442
2009 Basu S, Broxmeyer HE. CCR5 ligands modulate CXCL12-induced chemotaxis, adhesion, and Akt phosphorylation of human cord blood CD34+ cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 7478-88. PMID 19917679 DOI: 10.4049/Jimmunol.0900542  0.481
2009 Broxmeyer HE, Cooper S, Hass DM, Hathaway JK, Stehman FB, Hangoc G. Experimental basis of cord blood transplantation. Bone Marrow Transplantation. 44: 627-33. PMID 19802026 DOI: 10.1038/Bmt.2009.285  0.451
2009 Campbell TB, Basu S, Hangoc G, Tao W, Broxmeyer HE. Overexpression of Rheb2 enhances mouse hematopoietic progenitor cell growth while impairing stem cell repopulation. Blood. 114: 3392-401. PMID 19690340 DOI: 10.1182/Blood-2008-12-195214  0.531
2009 Stumpo DJ, Broxmeyer HE, Ward T, Cooper S, Hangoc G, Chung YJ, Shelley WC, Richfield EK, Ray MK, Yoder MC, Aplan PD, Blackshear PJ. Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis. Blood. 114: 2401-10. PMID 19633199 DOI: 10.1182/Blood-2009-04-214619  0.425
2009 Ou X, Chae H, Han M, Taylor T, Kim Y, Broxmeyer HE. SIRT1 Is Required for Mouse Embroyonic Stem Cell Commitment to Hematopoietic Cell Differentiation. Blood. 114: 811-811. DOI: 10.1182/Blood.V114.22.811.811  0.779
2009 Basu S, Broxmeyer HE. Role of Integrin Linked Kinase in Expansion and Chemotaxis of CD34+ Cord Blood Cells. Blood. 114: 3616-3616. DOI: 10.1182/Blood.V114.22.3616.3616  0.528
2009 Broxmeyer HE, Hoggatt J, Cooper S, Hangoc G, Pelus LM, Campbell TB. CD26/Dipeptidylpeptidase IV Regulates Potency of Selected Hematopoietic Growth Factors through Truncation, and Recovery In Vivo After Cytotoxic Stress. Blood. 114: 3602-3602. DOI: 10.1182/Blood.V114.22.3602.3602  0.481
2009 Kim JA, Hong OK, Hong JW, Broxmeyer HE. Astrocyte-Plexus Is Formed in the Neovascularization Induced by CD11b+ Cells From An Ischemic Hind-Limb Mouse Model. Blood. 114: 3043-3043. DOI: 10.1182/Blood.V114.22.3043.3043  0.41
2009 Mantel C, Messina-Graham S, Moh A, Fu X, Broxmeyer HE. The Earliest Stages of Loss of Stem Cell Self-Renewal in-Vivo Is Linked to Upregulated Biosynthesis of “Quiet” Mitochondria and Is Influenced by CXCR4 Activation and STAT3 Gene Deletion. Blood. 114: 2546-2546. DOI: 10.1182/Blood.V114.22.2546.2546  0.498
2009 Kinzfogl JM, Hangoc G, Broxmeyer HE. The Neurexin Iα/Neurexophilin1 Axis as a Myelosuppressive Factor in Human Cord Blood and Murine Bone Marrow Hematopoiesis. Blood. 114: 2545-2545. DOI: 10.1182/Blood.V114.22.2545.2545  0.845
2009 Rohrabaugh S, Hangoc G, Broxmeyer HE. Mad2 Haploinsufficiency Unexpectedly Protects Hematopoietic Progenitor Cells From Ara-C Mediated Cytotoxicity. Blood. 114: 2543-2543. DOI: 10.1182/Blood.V114.22.2543.2543  0.815
2009 Chae H, Broxmeyer HE. AMPK Regulates Nanog Gene Expression Via p53 in Mouse Embryonic Stem Cells. Blood. 114: 2537-2537. DOI: 10.1182/Blood.V114.22.2537.2537  0.366
2009 Kim Y, Broxmeyer HE. Phagocytosis May Be a Regulatory Mechanism for Myeloid Dendritic Cells to Terminate Type 1 CD8 + T Cells. Blood. 114: 1654-1654. DOI: 10.1182/Blood.V114.22.1654.1654  0.424
2009 Broxmeyer HE. Cord Blood Hematopoietic Stem and Progenitor Cells Essentials of Stem Cell Biology. 151-156. DOI: 10.1016/B978-0-12-374729-7.00017-2  0.351
2008 Strack RL, Strongin DE, Bhattacharyya D, Tao W, Berman A, Broxmeyer HE, Keenan RJ, Glick BS. A noncytotoxic DsRed variant for whole-cell labeling. Nature Methods. 5: 955-7. PMID 18953349 DOI: 10.1038/Nmeth.1264  0.344
2008 Mantel CR, Wang RH, Deng C, Broxmeyer HE. Sirt1, notch and stem cell "age asymmetry". Cell Cycle (Georgetown, Tex.). 7: 2821-5. PMID 18797187 DOI: 10.4161/Cc.7.18.6517  0.445
2008 Rohrabaugh S, Mantel C, Broxmeyer HE. Mouse hematopoietic stem cells, unlike human and mouse embryonic stem cells, exhibit checkpoint-apoptosis coupling. Stem Cells and Development. 17: 1017-20. PMID 18788999 DOI: 10.1182/Blood.V110.11.3357.3357  0.84
2008 Liu Y, Hangoc G, Campbell TB, Goodman M, Tao W, Pollok K, Srour EF, Broxmeyer HE. Identification of parameters required for efficient lentiviral vector transduction and engraftment of human cord blood CD34(+) NOD/SCID-repopulating cells. Experimental Hematology. 36: 947-56. PMID 18640494 DOI: 10.1016/J.Exphem.2008.06.005  0.467
2008 Mantel C, Broxmeyer HE. Sirtuin 1, stem cells, aging, and stem cell aging. Current Opinion in Hematology. 15: 326-31. PMID 18536570 DOI: 10.1097/Moh.0B013E3283043819  0.392
2008 Pulliam AC, Hobson MJ, Ciccone SL, Li Y, Chen S, Srour EF, Yang FC, Broxmeyer HE, Clapp DW. AMD3100 synergizes with G-CSF to mobilize repopulating stem cells in Fanconi anemia knockout mice. Experimental Hematology. 36: 1084-90. PMID 18495331 DOI: 10.1016/J.Exphem.2008.03.016  0.449
2008 Han MK, Song EK, Guo Y, Ou X, Mantel C, Broxmeyer HE. SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization. Cell Stem Cell. 2: 241-51. PMID 18371449 DOI: 10.1016/J.Stem.2008.01.002  0.602
2008 Singh P, Yao Y, Weliver A, Broxmeyer HE, Hong SC, Chang CH. Vaccinia virus infection modulates the hematopoietic cell compartments in the bone marrow. Stem Cells (Dayton, Ohio). 26: 1009-16. PMID 18258722 DOI: 10.1634/Stemcells.2007-0461  0.426
2008 Mantel C, Guo Y, Lee MR, Han MK, Rhorabough S, Kim KS, Broxmeyer HE. Cells enter a unique intermediate 4N stage, not 4N-G1, after aborted mitosis. Cell Cycle (Georgetown, Tex.). 7: 484-92. PMID 18235235 DOI: 10.4161/Cc.7.4.5316  0.411
2008 Broxmeyer HE. Chemokines in hematopoiesis. Current Opinion in Hematology. 15: 49-58. PMID 18043246 DOI: 10.1097/Moh.0B013E3282F29012  0.462
2008 Kim YJ, Han MK, Broxmeyer HE. 4-1BB regulates NKG2D costimulation in human cord blood CD8+ T cells. Blood. 111: 1378-86. PMID 18024793 DOI: 10.1182/Blood-2007-01-069450  0.452
2008 Campbell TB, Broxmeyer HE. CD26 inhibition and hematopoiesis: a novel approach to enhance transplantation. Frontiers in Bioscience : a Journal and Virtual Library. 13: 1795-805. PMID 17981668 DOI: 10.2741/2800  0.464
2008 Guo Y, Mantel C, Hromas RA, Broxmeyer HE. Oct-4 is critical for survival/antiapoptosis of murine embryonic stem cells subjected to stress: effects associated with Stat3/survivin. Stem Cells (Dayton, Ohio). 26: 30-4. PMID 17932422 DOI: 10.1634/Stemcells.2007-0401  0.482
2008 Taylor T, Derbigny W, Kim Y, Broxmeyer HE. Expression of Functional Toll-Like Receptor 2 on Mouse Embryonic Stem Cells Blood. 112: 4746-4746. DOI: 10.1182/Blood.V112.11.4746.4746  0.689
2008 Kim Y, Aisen AT, Broxmeyer HE. Myeloid-Derived Suppressor Cell Regulation of PD-1 Expression on, and Longevity of, Human CD8 + T Cells Blood. 112: 2562-2562. DOI: 10.1182/Blood.V112.11.2562.2562  0.408
2008 Broxmeyer HE, Cooper S, Hangoc G, Campbell TB. Inhibition of CD26/Dipeptidylpeptidase IV Enhances Proliferation of Hematopoietic Progenitor Cells Induced by Selected Colony Stimulating Factors Blood. 112: 2456-2456. DOI: 10.1182/Blood.V112.11.2456.2456  0.481
2008 Kim JA, March K, Chae H, Johnstone B, Cook T, Merfeld-Clauss S, Broxmeyer HE. Purified Gr1+CD11b+ Cells Induce Neovascularization in An Ischemic Hind Limb Mouse Model. Blood. 112: 1894-1894. DOI: 10.1182/Blood.V112.11.1894.1894  0.434
2008 Mantel C, Broxmeyer HE. Embryonic Stem Cells Bypass Numerous Cell Cycle Checkpoints; Not Just G1. Blood. 112: 1331-1331. DOI: 10.1182/Blood.V112.11.1331.1331  0.371
2008 Fu X, Zhang W, Cooper S, Hangoc G, Moh A, Broxmeyer HE. Potential roles of STAT3 in control of differentiation of hematopoietic and neuronal progenitors Cell Research. 18: S14-S14. DOI: 10.1038/Cr.2008.104  0.305
2008 Burns-Booth KL, Cornetta K, Broxmeyer HE, Touloukian CE. QS319. Enhancing Tumor Immunity Through the Transfer of a Lentiviral Construct Into Hematopoietci Stem Cells Journal of Surgical Research. 144: 393. DOI: 10.1016/J.Jss.2007.12.570  0.36
2008 Ha SP, Cornetta K, Broxmeyer HE, Restifo NP, Touloukian CE. 65. CD4+ T Cell Immunity Following Gene Transfer Into Hematopoietic Stem Cells Journal of Surgical Research. 144: 204-205. DOI: 10.1016/J.Jss.2007.12.075  0.438
2007 Broxmeyer HE. Mechanism unknown: prostaglandin E2 may improve HSC therapies. Cell Stem Cell. 1: 135-6. PMID 18371345 DOI: 10.1016/J.Stem.2007.05.008  0.349
2007 Kang SG, Lim HW, Andrisani OM, Broxmeyer HE, Kim CH. Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 179: 3724-33. PMID 17785809 DOI: 10.4049/Jimmunol.179.6.3724  0.427
2007 Broxmeyer HE, Mejia JA, Hangoc G, Barese C, Dinauer M, Cooper S. SDF-1/CXCL12 enhances in vitro replating capacity of murine and human multipotential and macrophage progenitor cells. Stem Cells and Development. 16: 589-96. PMID 17784832 DOI: 10.1089/Scd.2007.0044  0.535
2007 Basu S, Ray NT, Atkinson SJ, Broxmeyer HE. Protein phosphatase 2A plays an important role in stromal cell-derived factor-1/CXC chemokine ligand 12-mediated migration and adhesion of CD34+ cells. Journal of Immunology (Baltimore, Md. : 1950). 179: 3075-85. PMID 17709522 DOI: 10.4049/Jimmunol.179.5.3075  0.488
2007 Okabe S, Tauchi T, Nakajima A, Sashida G, Gotoh A, Broxmeyer HE, Ohyashiki JH, Ohyashiki K. Depsipeptide (FK228) preferentially induces apoptosis in BCR/ABL-expressing cell lines and cells from patients with chronic myelogenous leukemia in blast crisis. Stem Cells and Development. 16: 503-14. PMID 17610380 DOI: 10.1089/Scd.2007.9994  0.385
2007 Campbell TB, Hangoc G, Liu Y, Pollok K, Broxmeyer HE. Inhibition of CD26 in human cord blood CD34+ cells enhances their engraftment of nonobese diabetic/severe combined immunodeficiency mice. Stem Cells and Development. 16: 347-54. PMID 17610364 DOI: 10.1089/Scd.2007.9995  0.41
2007 Li G, Abediankenari S, Kim YJ, Campbell TB, Ito S, Graham-Evans B, Cooper S, Broxmeyer HE. TGF-beta combined with M-CSF and IL-4 induces generation of immune inhibitory cord blood dendritic cells capable of enhancing cytokine-induced ex vivo expansion of myeloid progenitors. Blood. 110: 2872-9. PMID 17585053 DOI: 10.1182/Blood-2006-10-050583  0.576
2007 Broxmeyer HE, Sehra S, Cooper S, Toney LM, Kusam S, Aloor JJ, Marchal CC, Dinauer MC, Dent AL. Aberrant regulation of hematopoiesis by T cells in BAZF-deficient mice. Molecular and Cellular Biology. 27: 5275-85. PMID 17526724 DOI: 10.1128/Mcb.01967-05  0.414
2007 Altenburg JD, Broxmeyer HE, Jin Q, Cooper S, Basu S, Alkhatib G. A naturally occurring splice variant of CXCL12/stromal cell-derived factor 1 is a potent human immunodeficiency virus type 1 inhibitor with weak chemotaxis and cell survival activities. Journal of Virology. 81: 8140-8. PMID 17507482 DOI: 10.1128/Jvi.00268-07  0.432
2007 Broxmeyer HE, Dent A, Cooper S, Hangoc G, Wang ZY, Du W, Gervay-Haque J, Sriram V, Renukaradhya GJ, Brutkiewicz RR. A role for natural killer T cells and CD1d molecules in counteracting suppression of hematopoiesis in mice induced by infection with murine cytomegalovirus. Experimental Hematology. 35: 87-93. PMID 17379092 DOI: 10.1016/J.Exphem.2007.01.015  0.406
2007 Broxmeyer HE, Li J, Hangoc G, Cooper S, Tao W, Mantel C, Graham-Evans B, Ghilardi N, de Sauvage FJ. Regulation of myeloid progenitor cell proliferation/survival by IL-31 receptor and IL-31. Experimental Hematology. 35: 78-86. PMID 17379091 DOI: 10.1016/J.Exphem.2007.01.028  0.333
2007 Broxmeyer HE, Hangoc G, Cooper S, Campbell T, Ito S, Mantel C. AMD3100 and CD26 modulate mobilization, engraftment, and survival of hematopoietic stem and progenitor cells mediated by the SDF-1/CXCL12-CXCR4 axis. Annals of the New York Academy of Sciences. 1106: 1-19. PMID 17360804 DOI: 10.1196/Annals.1392.013  0.515
2007 Mantel C, Broxmeyer HE. A new connection between the spindle checkpoint, asymmetric cell division and cytokine signaling. Cell Cycle (Georgetown, Tex.). 6: 144-6. PMID 17314513 DOI: 10.4161/Cc.6.2.3791  0.463
2007 Mantel C, Guo Y, Lee MR, Kim MK, Han MK, Shibayama H, Fukuda S, Yoder MC, Pelus LM, Kim KS, Broxmeyer HE. Checkpoint-apoptosis uncoupling in human and mouse embryonic stem cells: a source of karyotpic instability. Blood. 109: 4518-27. PMID 17289813 DOI: 10.1182/Blood-2006-10-054247  0.453
2007 Li G, Basu S, Han MK, Kim YJ, Broxmeyer HE. Influence of ERK activation on decreased chemotaxis of mature human cord blood monocyte-derived dendritic cells to CCL19 and CXCL12. Blood. 109: 3173-6. PMID 17179222 DOI: 10.1182/Blood-2006-04-014753  0.589
2007 Tao W, Evans BG, Yao J, Cooper S, Cornetta K, Ballas CB, Hangoc G, Broxmeyer HE. Enhanced green fluorescent protein is a nearly ideal long-term expression tracer for hematopoietic stem cells, whereas DsRed-express fluorescent protein is not. Stem Cells (Dayton, Ohio). 25: 670-8. PMID 17138958 DOI: 10.1634/Stemcells.2006-0553  0.432
2007 Mehta SA, Christopherson KW, Bhat-Nakshatri P, Goulet RJ, Broxmeyer HE, Kopelovich L, Nakshatri H. Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: implications of p53 mutation or isoform expression on breast cancer cell invasion. Oncogene. 26: 3329-37. PMID 17130833 DOI: 10.1038/Sj.Onc.1210120  0.339
2007 Ito S, Mantel CR, Han MK, Basu S, Fukuda S, Cooper S, Broxmeyer HE. Mad2 is required for optimal hematopoiesis: Mad2 associates with c-Kit in MO7e cells. Blood. 109: 1923-30. PMID 17038523 DOI: 10.1182/Blood-2006-06-030841  0.488
2007 Chen J, Yu WM, Daino H, Broxmeyer HE, Druker BJ, Qu CK. SHP-2 phosphatase is required for hematopoietic cell transformation by Bcr-Abl. Blood. 109: 778-85. PMID 17003374 DOI: 10.1182/Blood-2006-04-019141  0.426
2007 Broxmeyer HE, Campbell TB. Modulating the Interaction of Stromal-cell-derived Factor-1/CXCL12 and its Receptor, CXCR4, for Enhanced Mobilisation, Homing and Engraftment of Haematopoietic Stem Cells Oral History Review. 43. DOI: 10.17925/Ohr.2007.01.01.43  0.469
2007 Broxmeyer HE, Campbell TB, Cooper S, Hangoc G. Inhibition/Depletion of CD26/DPPIV Enhances Survival Promoting Activity of SDF-1/CXCL12 and Myelosuppressive Activities of Inhibitory Chemokines on Hematopoietic Progenitor Cells. Blood. 110: 610-610. DOI: 10.1182/Blood.V110.11.610.610  0.442
2007 Broxmeyer HE, Srour EF, Cooper S, Wallace CT, Hangoc G, Youn B. Selected Members of the Angiopoietin-Like Family of Human Proteins Enhance Survival and Replating Capacity of Immature Human Hematopoietic Progenitor Cells. Blood. 110: 3367-3367. DOI: 10.1182/Blood.V110.11.3367.3367  0.51
2007 Mantel C, Rhorabough S, Guo Y, Lee M, Han M, Kim K, Broxmeyer HE. Molecular Mechanisms of Spindle Checkpoint-Apoptosis Linkage and Karyotypic Stability in Stem Cells. Blood. 110: 3361-3361. DOI: 10.1182/Blood.V110.11.3361.3361  0.481
2007 Kim Y, Broxmeyer HE. Myeloid Derived Dendritic Cells Inhibit CD8+ T Cell Responses by Down-Modulating NKG2D and 4–1BB Expression. Blood. 110: 315-315. DOI: 10.1182/Blood.V110.11.315.315  0.446
2007 Ruffin PL, Kim Y, Broxmeyer HE. Autologous Human Cord Blood CD4 + CD25 + T Cells Stimulate CD8 + T Cell Killing Activity, and Their Expression of NKG2D and Granzyme B. Blood. 110: 2297-2297. DOI: 10.1182/Blood.V110.11.2297.2297  0.388
2007 Basu S, Broxmeyer HE. Modulation of Responsiveness of Human CD34+ Cells to CXL12/SDF-1 through Desensitization of CXCR4 by CCR5 Chemokines: Possible Implications for Mobilization during Inflammation. Blood. 110: 2238-2238. DOI: 10.1182/Blood.V110.11.2238.2238  0.461
2007 Tao W, Han M, Broxmeyer HE. A Cytoplasmic Fusion/Cell Division Model for Renewal of Hematopoietic Stem Cell. Blood. 110: 2225-2225. DOI: 10.1182/Blood.V110.11.2225.2225  0.519
2007 Campbell TB, Hangoc G, Tao W, Broxmeyer HE. Overexpression of Rheb2 Has Diverse Effects on Hematopoietic Progenitor and Stem Cell Functions. Blood. 110: 1274-1274. DOI: 10.1182/Blood.V110.11.1274.1274  0.564
2007 Broxmeyer HE. Cited2: Master regulator of HSC function? Blood. 110: 2787-2788. DOI: 10.1182/Blood-2007-08-105437  0.411
2007 Broxmeyer HE. 6: Effect of CD26 on Cord Blood, and Other Means to Enhance Engraftment of Hematopoietic Stem Cells Biology of Blood and Marrow Transplantation. 13: 1394-1395. DOI: 10.1016/J.Bbmt.2007.08.014  0.446
2006 Broxmeyer HE, Srour E, Orschell C, Ingram DA, Cooper S, Plett PA, Mead LE, Yoder MC. Cord blood stem and progenitor cells. Methods in Enzymology. 419: 439-73. PMID 17141066 DOI: 10.1016/S0076-6879(06)19018-7  0.507
2006 Broxmeyer HE, Cooper S, Hangoc G, Chang CH. Class II transactivator-mediated regulation of major histocompatibility complex class II antigen expression is important for hematopoietic progenitor cell suppression by chemokines and iron-binding proteins. Experimental Hematology. 34: 1078-84. PMID 16863914 DOI: 10.1016/J.Exphem.2006.04.008  0.353
2006 Broxmeyer HE, Pelus LM, Kim CH, Hangoc G, Cooper S, Hromas R. Synergistic inhibition in vivo of bone marrow myeloid progenitors by myelosuppressive chemokines and chemokine-accelerated recovery of progenitors after treatment of mice with Ara-C. Experimental Hematology. 34: 1069-77. PMID 16863913 DOI: 10.1016/J.Exphem.2006.04.007  0.454
2006 Porecha NK, English K, Hangoc G, Broxmeyer HE, Christopherson KW. Enhanced functional response to CXCL12/SDF-1 through retroviral overexpression of CXCR4 on M07e cells: implications for hematopoietic stem cell transplantation. Stem Cells and Development. 15: 325-33. PMID 16846371 DOI: 10.1089/Scd.2006.15.325  0.513
2006 Broxmeyer HE, Starnes T, Ramsey H, Cooper S, Dahl R, Williamson E, Hromas R. The IL-17 cytokine family members are inhibitors of human hematopoietic progenitor proliferation. Blood. 108: 770. PMID 16822904 DOI: 10.1182/Blood-2006-01-0292  0.45
2006 Lim HW, Broxmeyer HE, Kim CH. Regulation of trafficking receptor expression in human Forkhead Box P3 + regulatory T cells Journal of Immunology. 177: 840-851. PMID 16818738 DOI: 10.4049/Jimmunol.177.2.840  0.431
2006 Broxmeyer HE, Ginras AC, Sonenberg N, Cooper S. Retraction. Macrophage inflammatory protein-1alpha and interferon-inducible protein 10 inhibit synergistically induced growth factor stimulation of MAP kinase activity and suppress phosphorylation of eukaryotic initiation factor 4E and 4E binding protein 1. Blood. 107: 4713. PMID 16754774 DOI: 10.1182/Blood-2006-04-019281  0.331
2006 Okabe S, Tauchi T, Ohyashiki K, Broxmeyer HE. Stromal-cell-derived factor-1/CXCL12-induced chemotaxis of a T cell line involves intracellular signaling through Cbl and Cbl-b and their regulation by Src kinases and CD45. Blood Cells, Molecules & Diseases. 36: 308-14. PMID 16503409 DOI: 10.1016/J.Bcmd.2005.12.035  0.404
2006 Guo Y, Graham-Evans B, Broxmeyer HE. Murine embryonic stem cells secrete cytokines/growth modulators that enhance cell survival/anti-apoptosis and stimulate colony formation of murine hematopoietic progenitor cells Stem Cells. 24: 850-856. PMID 16339641 DOI: 10.1634/Stemcells.2005-0457  0.525
2006 Kim Y, Han M, Broxmeyer HE. Role of 4-1BB as a Regulator for NKG2D Costimulation in Human CD8+ T Cells. Blood. 108: 923-923. DOI: 10.1182/Blood.V108.11.923.923  0.45
2006 Okabe S, Tauchi T, Broxmeyer HE, Ohyashiki K. Depsipeptide (FK228) Preferntially Induces Apoptosis in Acute T-Cell Leukemia Cell Lines Mediated by CD45 and Src Kinase. Blood. 108: 4468-4468. DOI: 10.1182/Blood.V108.11.4468.4468  0.442
2006 Ito S, Mantel C, Ishida Y, Broxmeyer HE. Mitotic Arrest Deficiency 2 (Mad2) Is Required for Proliferative Synergy of GM-CSF Plus SCF in Hematopoietic Progenitors Via Effects on Apoptosis and Is Mediated by Ligand-Dependent Association of Mad2 with SCF and GM-CSF Receptors. Blood. 108: 4225-4225. DOI: 10.1182/Blood.V108.11.4225.4225  0.465
2006 Pulliam AC, Hobson MJ, Yang F, Broxmeyer HE, Clapp DW. AMD3100 and G-CSF Synergize To Promote Repopulating Stem Cell Mobilization in Fanca −/− and Fancc −/− Mice. Blood. 108: 3760-3760. DOI: 10.1182/Blood.V108.11.3760.3760  0.451
2006 Guo Y, Mantel C, Hromas RA, Broxmeyer HE. Oct-4 Is Crucial for Stress-Induced Murine Embryonic Stem Cell Survival/Anti-Apoptosis Mediated by STAT3/Survivin. Blood. 108: 277-277. DOI: 10.1182/Blood.V108.11.277.277  0.446
2006 Okabe S, Tauchi T, Broxmeyer HE, Ohyashiki K. Mechanism of Drug Resistance to Dasatinib (BMS-354825) and Imatinib in Chronic Myelogenous Leukemia Cells. Blood. 108: 1386-1386. DOI: 10.1182/Blood.V108.11.1386.1386  0.335
2006 Campbell TB, Tao W, Broxmeyer HE. Overexpression of Ras Homologue Enriched in Brain Like-1 (RhebL1) Leads to Positive Effects on Mouse Hematopoietic Progenitor Cells. Blood. 108: 1142-1142. DOI: 10.1182/Blood.V108.11.1142.1142  0.538
2006 Basu S, Ray NT, Atkinson SJ, Broxmeyer HE. Protein Phosphatase 2A Plays an Essential Role in Migration of CD34+ Cells to SDF-1/CXCL12. Blood. 108: 1131-1131. DOI: 10.1182/Blood.V108.11.1131.1131  0.49
2006 Broxmeyer HE. Going home: Inhibiting stem cell CD26 Blood. 108: 3966. DOI: 10.1182/Blood-2006-10-048785  0.448
2005 Vadhan-Raj S, Trent J, Burgess MA, Patel S, Collard ML, Zachariah G, Hangoc G, Johnson M, Broxmeyer HE, Benjamin RS. Once per cycle combination of long-acting hematopoietic growth factors (HGFs) pegfilgrastim and darbepoetin alfa (Peg-G + DPO) to reduce multi-lineage hematopoietic toxicity of chemotherapy with doxorubicin and ifosfamide (AI) in patients with sarcoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 8225. PMID 27944018 DOI: 10.1200/Jco.2005.23.16_Suppl.8225  0.352
2005 Guo Y, Hangoc G, Bian H, Pelus LM, Broxmeyer HE. SDF-1/CXCL12 enhances survival and chemotaxis of murine embryonic stem cells and production of primitive and definitive hematopoietic progenitor cells. Stem Cells (Dayton, Ohio). 23: 1324-32. PMID 16210409 DOI: 10.1634/Stemcells.2005-0085  0.517
2005 Broxmeyer HE. Biology of cord blood cells and future prospects for enchanced clinical benefit Cytotherapy. 7: 209-218. PMID 16081347 DOI: 10.1080/14653240510027190  0.382
2005 Zhang J, Li G, Bafica A, Pantelic M, Zhang P, Broxmeyer H, Liu Y, Wetzler L, He JJ, Chen T. Neisseria gonorrhoeae enhances infection of dendritic cells by HIV type 1. Journal of Immunology (Baltimore, Md. : 1950). 174: 7995-8002. PMID 15944306 DOI: 10.4049/Jimmunol.174.12.7995  0.512
2005 Broxmeyer HE, Cooper S, Hangoc G, Kim CH. Stromal cell-derived factor-1/CXCL12 selectively counteracts inhibitory effects of myelosuppressive chemokines on hematopoietic progenitor cell proliferation in vitro. Stem Cells and Development. 14: 199-203. PMID 15910246 DOI: 10.1089/Scd.2005.14.199  0.502
2005 Broxmeyer HE, Cooper S, Lasky LA, De Sauvage F. Identification of a massive reserve of hematopoietic progenitors in mice. Stem Cells and Development. 14: 105-10. PMID 15910237 DOI: 10.1089/Scd.2005.14.105  0.401
2005 Broxmeyer HE, Orschell CM, Clapp DW, Hangoc G, Cooper S, Plett PA, Liles WC, Li X, Graham-Evans B, Campbell TB, Calandra G, Bridger G, Dale DC, Srour EF. Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist Journal of Experimental Medicine. 201: 1307-1318. PMID 15837815 DOI: 10.1084/Jem.20041385  0.523
2005 Li G, Kim YJ, Broxmeyer HE. Macrophage colony-stimulating factor drives cord blood monocyte differentiation into IL-10(high)IL-12absent dendritic cells with tolerogenic potential. Journal of Immunology (Baltimore, Md. : 1950). 174: 4706-17. PMID 15814695 DOI: 10.4049/Jimmunol.174.8.4706  0.61
2005 Basu S, Broxmeyer HE. Transforming growth factor-β1 modulates responses of CD34+ cord blood cells to stromal cell-derived factor-1/CXCL12 Blood. 106: 485-493. PMID 15797995 DOI: 10.1182/Blood-2004-10-4145  0.44
2005 Liles WC, Rodger E, Broxmeyer HE, Dehner C, Badel K, Calandra G, Christensen J, Wood B, Price TH, Dale DC. Augmented mobilization and collection of CD34+ hematopoietic cells from normal human volunteers stimulated with granulocyte-colony-stimulating factor by single-dose administration of AMD3100, a CXCR4 antagonist Transfusion. 45: 295-300. PMID 15752146 DOI: 10.1111/J.1537-2995.2005.04222.X  0.432
2005 Hou YH, Srour EF, Ramsey H, Dahl R, Broxmeyer HE, Hromas R. Identification of a human B-cell/myeloid common progenitor by the absence of CXCR4. Blood. 105: 3488-92. PMID 15650059 DOI: 10.1182/Blood-2004-07-2839  0.47
2005 Fukuda S, Broxmeyer HE, Pelus LM. Flt3 ligand and the Flt3 receptor regulate hematopoietic cell migration by modulating the SDF-1alpha(CXCL12)/CXCR4 axis. Blood. 105: 3117-26. PMID 15618475 DOI: 10.1182/Blood-2004-04-1440  0.471
2005 Joo EK, Broxmeyer HE, Kwon HJ, Kang HB, Kim JS, Lim JS, Choe YK, Choe IS, Myung PK, Lee Y. Enhancement of cell survival by stromal cell-derived factor-1/CXCL12 involves activation of CREB and induction of Mcl-1 and c-Fos in factor-dependent human cell line MO7e. Stem Cells and Development. 13: 563-70. PMID 15588513 DOI: 10.1089/Scd.2004.13.563  0.46
2005 Yu RY, Wang X, Pixley FJ, Yu JJ, Dent AL, Broxmeyer HE, Stanley ER, Ye BH. BCL-6 negatively regulates macrophage proliferation by suppressing autocrine IL-6 production. Blood. 105: 1777-84. PMID 15507530 DOI: 10.1182/Blood-2004-08-3171  0.429
2005 Kim YJ, Stringfield TM, Chen Y, Broxmeyer HE. Modulation of cord blood CD8+ T-cell effector differentiation by TGF-beta1 and 4-1BB costimulation. Blood. 105: 274-81. PMID 15353478 DOI: 10.1182/Blood-2003-12-4343  0.368
2005 Okabe S, Fukuda S, Kim YJ, Niki M, Pelus LM, Ohyashiki K, Pandolfi PP, Broxmeyer HE. Stromal cell-derived factor-1alpha/CXCL12-induced chemotaxis of T cells involves activation of the RasGAP-associated docking protein p62Dok-1. Blood. 105: 474-80. PMID 15345598 DOI: 10.1182/Blood-2004-03-0843  0.387
2005 Li G, Han M, Broxmeyer HE. Decreased Responsiveness of Mature Dendritic Cells from Cord Blood to Chemotaxis Induced by CXCR4 Ligand CXCL12, and CCR7 Ligand CCL19 May Explain Lowered GVHD Associated with Cord Blood Tranplantation. Blood. 106: 766-766. DOI: 10.1182/Blood.V106.11.766.766  0.59
2005 Ito S, Mantel C, Han M, Fukuda S, Ishida Y, Benezra R, Broxmeyer HE. Mad2 (Mitotic Arrest Deficiency 2) Is Essential for the Synergistic Proliferation Induced by Stem Cell Factor Combined with GM-CSF in Hematopoietic Progenitor Cells, Effects Reflecting the Association of c-kit with Mad2. Blood. 106: 71-71. DOI: 10.1182/Blood.V106.11.71.71  0.524
2005 Broxmeyer HE, Dent A, Cooper S, Hangoc G, Renukaradhya GJ, Sriram V, Brutkiewicz RR. An Important Role for CD1d and NKT Cells in the Suppression of Hematopoiesis in Mice Induced by Infection with Cytomegalovirus. Blood. 106: 574-574. DOI: 10.1182/Blood.V106.11.574.574  0.417
2005 Han M, Mantel C, Guo Y, Tao W, Broxmeyer HE. Role of SIRT1 in Proliferation and Self-Renewal of Mouse Embryonic Stem Cells. Blood. 106: 520-520. DOI: 10.1182/Blood.V106.11.520.520  0.404
2005 Okabe S, Tauchi T, Nakajima A, Sashida G, Sumi M, Gotoh A, Broxmeyer HE, Ohyashiki JH, Ohyashiki K. Depsipeptide (FK228) Preferentially Induces Apoptosis in BCR/ABL-Expressing TF-1 Cells. Blood. 106: 4845-4845. DOI: 10.1182/Blood.V106.11.4845.4845  0.432
2005 Graham-Evans B, Broxmeyer H. Effect of Arsenic Trioxide on E14 Murine Embryonic Stem Cells In Vitro. Blood. 106: 4409-4409. DOI: 10.1182/Blood.V106.11.4409.4409  0.439
2005 Kim Y, Broxmeyer HE. TGF-β1 Regulates NKG2D Promoted Effector Differentiation by Induction of CD30 and Suppression of CD137 in Umbilical Cord Blood CD8+ T Cells. Blood. 106: 3319-3319. DOI: 10.1182/Blood.V106.11.3319.3319  0.362
2005 Mantel CR, Guo Y, Han M, Roharbaugh S, Graham-Evans B, Yoder MC, Hromas RA, Broxmeyer HE. oct-4 Is Essential for Aneuploidy/Polyploidy-Tolerance in Embryonic Stem (ES) Cells and the Fate of Tetraploid ES Cells during Early Differentiation. Blood. 106: 311-311. DOI: 10.1182/Blood.V106.11.311.311  0.486
2005 Tao W, Graham-Evans B, Cooper S, Cornetta K, Ballas CB, Hangoc G, Broxmeyer HE. EGFP Is a Useful Long-Term Expression Tracer for Hematopoietic Stem Cells While DsRed Fluorescent Protein Is Not. Blood. 106: 3057-3057. DOI: 10.1182/Blood.V106.11.3057.3057  0.496
2005 Li G, Campbell TB, Graham-Evans B, Cooper S, Broxmeyer HE. TGF-β1, in Synergy with M-CSF Induce Generation of a Novel Type of Human Cord Blood Dendritic Cell That Is Both Anti-Inflammatory and Capable of Ex-Vivo Expansion of Myeloid Progenitor Cells. Blood. 106: 2380-2380. DOI: 10.1182/Blood.V106.11.2380.2380  0.595
2005 Basu S, Graham-Evans B, Broxmeyer HE. Protein Phosphatase2A Regulates Stromal Cell- Derived Factor-1 Mediated Responses of CD34+ Cord Blood Cells. Blood. 106: 2279-2279. DOI: 10.1182/Blood.V106.11.2279.2279  0.493
2005 Campbell TB, Hangoc G, Broxmeyer HE. The Role of CD26 in Human Umbilical Cord Blood CD34+ Cell Engraftment of NOD/SCID Mice. Blood. 106: 1708-1708. DOI: 10.1182/Blood.V106.11.1708.1708  0.438
2005 Guo Y, Graham-Evans B, Mantal CR, Hromas RA, Broxmeyer HE. Oct-4 Is Crucial for Murine Embryonic Stem Cell Secretion of Cytokines/Growth Modulators That Enhance Cell Survival/Anti-Apoptosis of Murine ES Cells and Bone Marrow Hematopoietic Progenitor Cells. Blood. 106: 1359-1359. DOI: 10.1182/Blood.V106.11.1359.1359  0.53
2005 Broxmeyer HE, Ghilardi N, Hangoc G, Cooper S, Tao W, Mantel C, Graham-Evans B, deSauvage FJ. IL-31 Receptor and IL-31 in the Positive Regulation of Myeloid Progenitor Cell Proliferation/Survival. Blood. 106: 1347-1347. DOI: 10.1182/Blood.V106.11.1347.1347  0.346
2005 Broxmeyer HE, Cooper S, Hangoc G, Zhang W, Moh A, Welte T, Fu X. STAT3 Deletion after Birth Results in Marked Decreases in Absolute Numbers and Cell Cycling Status of Marrow and Spleen Myeloid Progenitor Cells, and STAT3 Is a Critical Molecule in Mediating Synergistically Stimulated Progenitor Cell Proliferation. Blood. 106: 1346-1346. DOI: 10.1182/Blood.V106.11.1346.1346  0.502
2005 Broxmeyer H, Christopherson K, Hangoc G, Campbell T. 15. Augmentation of homing of cord blood stem cells Biology of Blood and Marrow Transplantation. 11: 933. DOI: 10.1016/J.Bbmt.2005.08.014  0.421
2004 Hübel K, Liles WC, Broxmeyer HE, Rodger E, Wood B, Cooper S, Hangoc G, Macfarland R, Bridger GJ, Henson GW, Calandra G, Dale DC. Leukocytosis and Mobilization of CD34+ Hematopoietic Progenitor Cells by AMD3100, a CXCR4 Antagonist. Supportive Cancer Therapy. 1: 165-72. PMID 18628138 DOI: 10.3816/Sct.2004.N.008  0.485
2004 Parker GC, Anastassova-Kristeva M, Broxmeyer HE, Dodge WH, Eisenberg LM, Gehling UM, Guenin LM, Huss R, Moldovan NI, Rao M, Srour EF, Yoder MC. Stem cells: shibboleths of development. Stem Cells and Development. 13: 579-84. PMID 15684825 DOI: 10.1089/Scd.2004.13.579  0.44
2004 Tao W, Wang M, Voss ED, Cocklin RR, Smith JA, Cooper SH, Broxmeyer HE. Comparative proteomic analysis of human CD34+ stem/progenitor cells and mature CD15+ myeloid cells. Stem Cells (Dayton, Ohio). 22: 1003-14. PMID 15536191 DOI: 10.1634/Stemcells.22-6-1003  0.439
2004 Li G, Hangoc G, Broxmeyer HE. Interleukin-10 in combination with M-CSF and IL-4 contributes to development of the rare population of CD14+CD16++ cells derived from human monocytes. Biochemical and Biophysical Research Communications. 322: 637-43. PMID 15325277 DOI: 10.1016/J.Bbrc.2004.07.172  0.584
2004 Christopherson KW, Hangoc G, Mantel CR, Broxmeyer HE. Modulation of hematopoietic stem cell homing and engraftment by CD26. Science (New York, N.Y.). 305: 1000-3. PMID 15310902 DOI: 10.1126/Science.1097071  0.464
2004 Mantel C, Guo Y, Kauffman C, English D, Broxmeyer HE. Potential use of enucleated embryonic stem cell cytoplasts in investigations of stem cell fusion. Stem Cells and Development. 13: 165-7. PMID 15186731 DOI: 10.1089/154732804323046756  0.333
2004 Tao W, Hangoc G, Cooper S, Broxmeyer H. SDF-1α/CXCL12 enhances retroviral-mediated gene transfer into immature subsets of human and murine hematopoietic progenitor cells Gene Therapy. 11: 61-69. PMID 14681698 DOI: 10.1038/Sj.Gt.3302127  0.491
2004 Lee Y, Broxmeyer HE, Mantel C, Kwon HJ, Kim JW, Kim JS, Kwon D, Choe IS. Synergistic activation of p70S6 kinase associated with stem cell factor in MO7e cells. Experimental & Molecular Medicine. 35: 222-6. PMID 12858022 DOI: 10.1038/Emm.2003.30  0.448
2004 Broxmeyer HE, Christopherson KW. Stromal cell derived factor-1/CXCL12, CXCR4 and CD26 in the mobilization and homing of hematopoietic stem and progenitor cells Current Medicinal Chemistry: Anti-Inflammatory and Anti-Allergy Agents. 3: 303-311. DOI: 10.2174/1568014043355249  0.384
2004 Li G, Broxmeyer HE. M-CSF Drives Human Cord Blood Monocyte Differentiation along an Alternative Pathway into Suppressive CXCR4highIL-10highIL-12absentTNF-adefective Dendritic Cells. Blood. 104: 3446-3446. DOI: 10.1182/Blood.V104.11.3446.3446  0.635
2004 Kim Y, Stringfield TM, Chen Y, Broxmeyer HE. Modulation of Cord Blood CD8+ T Cell Effector Differentiation by 4-1BB and CD30: Cross-Talk with TGF-β1. Blood. 104: 3231-3231. DOI: 10.1182/Blood.V104.11.3231.3231  0.358
2004 Vadhan-Raj S, Bueso-Ramos CE, Hangoc G, Christopherson K, Collard M, Broxmeyer H. Expansion of Bone Marrow (BM) Progenitors and Mobilization of Multilineage Progenitor Cells Associated with Once Per Cycle Administration of Long-Acting Growth Factors Neulasta and Aranesp with Chemotherapy (CT): Biology and Nature of Response. Blood. 104: 2905-2905. DOI: 10.1182/Blood.V104.11.2905.2905  0.446
2004 Fukuda S, Broxmeyer HE, Pelus LM. Flt3 Ligand Negatively Regulates In Vitro Migration, Intracellular Signaling Activated by SDF-1α/CXCR4 and In Vivo Homing of Hematopoietic Progenitor Cells. Blood. 104: 2674-2674. DOI: 10.1182/Blood.V104.11.2674.2674  0.492
2004 Guo Y, Hangoc G, Bian H, Pelus LM, Broxmeyer HE. SDF-1/CXCL12 Enhances Survival of Murine Embryonic Stem Cells and Their Production of Myeloid Progenitors, but Not Hemangioblasts. Blood. 104: 1693-1693. DOI: 10.1182/Blood.V104.11.1693.1693  0.506
2004 Mantel C, Guo Y, Shibayama H, Fukuda S, Yoder MC, Pelus LM, Broxmeyer HE. Checkpoint Adaptation and Apoptosis Are Uncoupled in Mouse ES Cell Lines. Blood. 104: 1259-1259. DOI: 10.1182/Blood.V104.11.1259.1259  0.421
2004 Christopherson KW, Porecha NK, Hangoc G, Broxmeyer HE. Enhanced Functional Response to CXCL12/SDF-1 through Retroviral Overexpression of CXCR4: Implications for Hematopoietic Stem & Progenitor Cell Homing and Engraftment. Blood. 104: 1198-1198. DOI: 10.1182/Blood.V104.11.1198.1198  0.534
2004 Broxmeyer HE. Stem and Progenitor Cells Isolated from Cord Blood Handbook of Stem Cells. 2: 181-190. DOI: 10.1016/B978-012436643-5/50107-3  0.352
2003 Christopherson KW, Cooper S, Hangoc G, Broxmeyer HE. CD26 is essential for normal G-CSF-induced progenitor cell mobilization as determined by CD26-/- mice. Experimental Hematology. 31: 1126-34. PMID 14585379 DOI: 10.1016/J.Exphem.2003.07.002  0.422
2003 Kaplan MH, Chang HC, Cooper S, Lee Y, Broxmeyer HE. Distinct requirements for Stat4 and Stat6 in hematopoietic progenitor cell responses to growth factors and chemokines. Journal of Hematotherapy & Stem Cell Research. 12: 401-8. PMID 12965077 DOI: 10.1089/152581603322286033  0.507
2003 Liles WC, Broxmeyer HE, Rodger E, Wood B, Hübel K, Cooper S, Hangoc G, Bridger GJ, Henson GW, Calandra G, Dale DC. Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist Blood. 102: 2728-2730. PMID 12855591 DOI: 10.1182/Blood-2003-02-0663  0.477
2003 Liu L, Ding C, Zeng W, Heuer JG, Tetreault JW, Noblitt TW, Hangoc G, Cooper S, Brune KA, Sharma G, Fox N, Rowlinson SW, Rogers DP, Witcher DR, Lambooy PK, ... ... Broxmeyer HE, et al. Selective enhancement of multipotential hematopoietic progenitors in vitro and in vivo by IL-20. Blood. 102: 3206-9. PMID 12855566 DOI: 10.1182/Blood-2003-05-1419  0.402
2003 Freie B, Li X, Ciccone SL, Nawa K, Cooper S, Vogelweid C, Schantz L, Haneline LS, Orazi A, Broxmeyer HE, Lee SH, Clapp DW. Fanconi anemia type C and p53 cooperate in apoptosis and tumorigenesis. Blood. 102: 4146-52. PMID 12855557 DOI: 10.1182/Blood-2003-03-0971  0.375
2003 Li G, Kim YJ, Mantel C, Broxmeyer HE. P-selectin enhances generation of CD14+CD16+ dendritic-like cells and inhibits macrophage maturation from human peripheral blood monocytes. Journal of Immunology (Baltimore, Md. : 1950). 171: 669-77. PMID 12847232 DOI: 10.4049/Jimmunol.171.2.669  0.649
2003 Broxmeyer HE, Kohli L, Kim CH, Lee Y, Mantel C, Cooper S, Hangoc G, Shaheen M, Li X, Clapp DW. Stromal cell-derived factor-1/CXCL12 directly enhances survival/antiapoptosis of myeloid progenitor cells through CXCR4 and G(alpha)i proteins and enhances engraftment of competitive, repopulating stem cells. Journal of Leukocyte Biology. 73: 630-8. PMID 12714578 DOI: 10.1189/Jlb.1002495  0.533
2003 Helbig G, Christopherson KW, Bhat-Nakshatri P, Kumar S, Kishimoto H, Miller KD, Broxmeyer HE, Nakshatri H. NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4. The Journal of Biological Chemistry. 278: 21631-8. PMID 12690099 DOI: 10.1074/Jbc.M300609200  0.383
2003 Kim WY, Broxmeyer HE, Han IS, Park DH, Lee KM, Vinay DS, Kwon BS. Effect of leukotactin-1 on the protection in vivo of myeloid progenitor cells against cytotoxic chemotherapeutics. Journal of Hematotherapy & Stem Cell Research. 12: 107-13. PMID 12662441 DOI: 10.1089/152581603321210181  0.48
2003 Ra JS, Broxmeyer HE, Kim MW, Han IS, Choi SW, Kwon BS. Osteoprotegerin inhibits proliferation of myeloid progenitor cells. Journal of Hematotherapy & Stem Cell Research. 12: 33-8. PMID 12662434 DOI: 10.1089/152581603321210118  0.503
2003 Tao W, Hangoc G, Hawes JW, Si Y, Cooper S, Broxmeyer HE. Profiling of differentially expressed apoptosis-related genes by cDNA arrays in human cord blood CD34+ cells treated with etoposide. Experimental Hematology. 31: 251-60. PMID 12644023 DOI: 10.1016/S0301-472X(02)01083-4  0.441
2003 Christopherson KW, Cooper S, Broxmeyer HE. Cell surface peptidase CD26/DPPIV mediates G-CSF mobilization of mouse progenitor cells. Blood. 101: 4680-6. PMID 12576320 DOI: 10.1182/Blood-2002-12-3893  0.487
2003 Broxmeyer HE, Srour EF, Hangoc G, Cooper S, Anderson SA, Bodine DM. High-efficiency recovery of functional hematopoietic progenitor and stem cells from human cord blood cryopreserved for 15 years. Proceedings of the National Academy of Sciences of the United States of America. 100: 645-50. PMID 12518050 DOI: 10.1073/Pnas.0237086100  0.52
2003 Broxmeyer HE, Cooper S, Kohli L, Hangoc G, Lee Y, Mantel C, Clapp DW, Kim CH. Transgenic expression of stromal cell-derived factor-1/CXC chemokine ligand 12 enhances myeloid progenitor cell survival/antiapoptosis in vitro in response to growth factor withdrawal and enhances myelopoiesis in vivo. Journal of Immunology (Baltimore, Md. : 1950). 170: 421-9. PMID 12496427 DOI: 10.4049/Jimmunol.170.1.421  0.506
2003 Haneline LS, Li X, Ciccone SL, Hong P, Yang Y, Broxmeyer HE, Lee SH, Orazi A, Srour EF, Clapp DW. Retroviral-mediated expression of recombinant Fancc enhances the repopulating ability of Fancc-/- hematopoietic stem cells and decreases the risk of clonal evolution. Blood. 101: 1299-307. PMID 12393504 DOI: 10.1182/Blood-2002-08-2404  0.464
2002 Okabe S, Fukuda S, Broxmeyer HE. Src kinase, but not the Src kinase family member p56lck, mediates stromal cell-derived factor 1 α/CXCL12-induced chemotaxis of a T cell line Journal of Hematotherapy and Stem Cell Research. 11: 923-928. PMID 12590707 DOI: 10.1089/152581602321080583  0.387
2002 Kim YJ, Li G, Broxmeyer HE. 4-1BB ligand stimulation enhances myeloid dendritic cell maturation from human umbilical cord blood CD34+ progenitor cells. Journal of Hematotherapy & Stem Cell Research. 11: 895-903. PMID 12590704 DOI: 10.1089/152581602321080556  0.639
2002 Christopherson KW, Hangoc G, Broxmeyer HE. Cell surface peptidase CD26/dipeptidylpeptidase IV regulates CXCL12/stromal cell-derived factor-1 alpha-mediated chemotaxis of human cord blood CD34+ progenitor cells. Journal of Immunology (Baltimore, Md. : 1950). 169: 7000-8. PMID 12471135 DOI: 10.4049/Jimmunol.169.12.7000  0.452
2002 Mack DL, Leibowitz DS, Cooper S, Ramsey H, Broxmeyer HE, Hromas R. Down-regulation of the myeloid homeobox protein Hex is essential for normal T-cell development Immunology. 107: 444-451. PMID 12460189 DOI: 10.1046/J.1365-2567.2002.01523.X  0.44
2002 Kim YJ, Brutkiewicz RR, Broxmeyer HE. Role of 4-1BB (CD137) in the functional activation of cord blood CD28(-)CD8(+) T cells. Blood. 100: 3253-60. PMID 12384425 DOI: 10.1182/Blood-2001-11-0136  0.378
2002 Hromas R, Cooper S, Broxmeyer HE. The chemokine CCL21 protects normal marrow progenitors from ara-C cytotoxicity Cancer Chemotherapy and Pharmacology. 50: 163-166. PMID 12172984 DOI: 10.1007/S00280-002-0486-7  0.4
2002 Okabe S, Fukuda S, Broxmeyer HE. Activation of Wiskott-Aldrich syndrome protein and its association with other proteins by stromal cell-derived factor-1α is associated with cell migration in a T-lymphocyte line Experimental Hematology. 30: 761-766. PMID 12135674 DOI: 10.1016/S0301-472X(02)00823-8  0.383
2002 Broxmeyer HE, Bruns HA, Zhang S, Cooper S, Hangoc G, McKenzie AN, Dent AL, Schindler U, Naeger LK, Hoey T, Kaplan MH. Th1 cells regulate hematopoietic progenitor cell homeostasis by production of oncostatin M. Immunity. 16: 815-25. PMID 12121663 DOI: 10.1016/S1074-7613(02)00319-9  0.669
2002 Starnes T, Broxmeyer HE, Robertson MJ, Hromas R. Cutting edge: IL-17D, a novel member of the IL-17 family, stimulates cytokine production and inhibits hemopoiesis. Journal of Immunology (Baltimore, Md. : 1950). 169: 642-6. PMID 12097364 DOI: 10.4049/Jimmunol.169.2.642  0.321
2002 Anzai N, Lee Y, Youn BS, Fukuda S, Kim YJ, Mantel C, Akashi M, Broxmeyer HE. C-kit associated with the transmembrane 4 superfamily proteins constitutes a functionally distinct subunit in human hematopoietic progenitors. Blood. 99: 4413-21. PMID 12036870 DOI: 10.1182/Blood.V99.12.4413  0.4
2002 Lee Y, Gotoh A, Kwon HJ, You M, Kohli L, Mantel C, Cooper S, Hangoc G, Miyazawa K, Ohyashiki K, Broxmeyer HE. Enhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokines. Blood. 99: 4307-17. PMID 12036856 DOI: 10.1182/Blood.V99.12.4307  0.426
2002 Kwon BS, Hurtado JC, Lee ZH, Kwack KB, Seo SK, Choi BK, Koller BH, Wolisi G, Broxmeyer HE, Vinay DS. Immune responses in 4-1BB (CD137)-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 168: 5483-90. PMID 12023342 DOI: 10.4049/Jimmunol.168.11.5483  0.364
2002 Dai MS, Chevallier N, Stone S, Heinrich MC, McConnell M, Reuter T, Broxmeyer HE, Licht JD, Lu L, Hoatlin ME. The effects of the Fanconi anemia zinc finger (FAZF) on cell cycle, apoptosis, and proliferation are differentiation stage-specific. The Journal of Biological Chemistry. 277: 26327-34. PMID 11986317 DOI: 10.1074/jbc.M201834200  0.356
2001 Cooper SH, Broxmeyer HE. Measurement of interleukin 3 and other hematopoietic cytokines, such as GM-CSF, G-CSF, M-CSF, erythropoietin, steel factor, and Flt-3 ligand Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. PMID 18432817 DOI: 10.1002/0471142735.Im0604S37  0.342
2001 Mantel C, Hendrie P, Broxmeyer HE. Steel factor regulates cell cycle asymmetry Stem Cells. 19: 483-491. PMID 11713339 DOI: 10.1634/Stemcells.19-6-483  0.506
2001 Starnes T, Robertson MJ, Sledge G, Kelich S, Nakshatri H, Broxmeyer HE, Hromas R. Cutting edge: IL-17F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production. Journal of Immunology (Baltimore, Md. : 1950). 167: 4137-40. PMID 11591732 DOI: 10.4049/Jimmunol.167.8.4137  0.4
2001 Broxmeyer HE. Regulation of hematopoiesis by chemokine family members International Journal of Hematology. 74: 9-17. PMID 11530812 DOI: 10.1007/Bf02982544  0.379
2001 Kim YJ, Broxmeyer HE. Therapeutic potential of 4-1BB (CD137) as a regulator for effector CD8+ T cells Journal of Hematotherapy and Stem Cell Research. 10: 441-449. PMID 11522228 DOI: 10.1089/15258160152509064  0.408
2001 Youn BS, Kim YJ, Mantel C, Yu KY, Broxmeyer HE. Blocking of c-FLIP(L)--independent cycloheximide-induced apoptosis or Fas-mediated apoptosis by the CC chemokine receptor 9/TECK interaction. Blood. 98: 925-33. PMID 11493434 DOI: 10.1182/Blood.V98.4.925  0.395
2001 Broxmeyer HE, Youn BS, Kim C, Hangoc G, Cooper S, Mantel C. Chemokine regulation of hematopoiesis and the involvement of pertussis toxin-sensitive G alpha i proteins. Annals of the New York Academy of Sciences. 938: 117-27; discussion 1. PMID 11458498 DOI: 10.1111/J.1749-6632.2001.Tb03580.X  0.378
2001 Gaboli M, Kotsi PA, Gurrieri C, Cattoretti G, Ronchetti S, Cordon-Cardo C, Broxmeyer HE, Hromas R, Pandolfi PP. Mzf1 controls cell proliferation and tumorigenesis. Genes & Development. 15: 1625-30. PMID 11445537 DOI: 10.1101/Gad.902301  0.481
2001 Crow M, Taub DD, Cooper S, Broxmeyer HE, Sarris AH. Human recombinant interferon-inducible protein-10: intact disulfide bridges are not required for inhibition of hematopoietic progenitors and chemotaxis of T lymphocytes and monocytes. Journal of Hematotherapy & Stem Cell Research. 10: 147-56. PMID 11276368 DOI: 10.1089/152581601750098417  0.414
2001 Lee Y, Broxmeyer HE. Synergistic activation of RSK correlates with c-fos induction in MO7e cells stimulated with GM-CSF plus steel factor Biochemical and Biophysical Research Communications. 281: 897-901. PMID 11237744 DOI: 10.1006/Bbrc.2001.4430  0.387
2001 Mantel CR, Braun SE, Lee Y, Kim YJ, Broxmeyer HE. The interphase microtubule damage checkpoint defines an S-phase commitment point and does not require p21(waf-1). Blood. 97: 1505-7. PMID 11222400 DOI: 10.1182/Blood.V97.5.1505  0.341
2001 Lee Y, Mantel C, Anzai N, Braun SE, Broxmeyer HE. Transcriptional and ERK1/2-dependent synergistic upregulation of p21(cip1/waf1) associated with steel factor synergy in MO7e. Biochemical and Biophysical Research Communications. 280: 675-83. PMID 11162574 DOI: 10.1006/Bbrc.2000.4215  0.354
2001 Xia ZB, Dai MS, Magoulas C, Broxmeyer HE, Lu L. Differentially expressed genes during in vitro differentiation of murine embryonic stem cells transduced with a human erythropoietin receptor cDNA. Journal of Hematotherapy & Stem Cell Research. 9: 651-8. PMID 11091489 DOI: 10.1089/15258160050196696  0.444
2000 Fang S, Steinmetz R, King DW, Zeng P, Vogelweid C, Cooper S, Hangcoc G, Broxmeyer HE, Pescovitz OH. Development of a Transgenic Mouse That Overexpresses a Novel Product of the Growth Hormone-Releasing Hormone Gene. Endocrinology. 141: 1377-1383. PMID 28201151 DOI: 10.1210/Endo.141.4.7422  0.364
2000 Miyazawa K, Nishimaki J, Katagiri T, Yaguchi M, Iwase O, Gotoh A, Tauchi T, Kawanishi Y, Toyama K, Ohyashiki K, Ishibashi T, Broxmeyer HE. Megakaryocytic Maturation is Regulated by Maintaining a Balance Against Cytokine Induced-cell Proliferation: Steel Factor Retards Thrombopoietin-induced Megakaryocytic Differentiation While Synergistically Stimulating Mitogenesis; Hematopoiesis. Hematology (Amsterdam, Netherlands). 5: 233-246. PMID 11399618 DOI: 10.1080/10245332.2000.11746512  0.521
2000 Lu L, Dai MS, Ge Y, Wang LS, Braun SE, Wait CL, Griffith DJ, Heinrich MC, Broxmeyer HE. Co-transduction of cDNAs for c-kit and steel factor into single CD34+ cord blood cells further enhances the growth of erythroid and multipotential progenitors Journal of Hematotherapy and Stem Cell Research. 9: 813-825. PMID 11177593 DOI: 10.1089/152581600750062246  0.493
2000 Youn BS, Mantel C, Broxmeyer HE. Chemokines, chemokine receptors and hematopoiesis Immunological Reviews. 177: 150-174. PMID 11138773 DOI: 10.1034/J.1600-065X.2000.17701.X  0.51
2000 Lu L, Ge Y, Li ZH, Dai MS, Broxmeyer HE. Enhancement of proliferation and differentiation of erythroid progenitors by co-transduction of erythropoietin receptor and H-ras cDNAs into single CD343+ cord blood cells Bone Marrow Transplantation. 26: 817-822. PMID 11081379 DOI: 10.1038/Sj.Bmt.1702620  0.398
2000 Zhang S, Broxmeyer HE. Flt3 ligand induces tyrosine phosphorylation of gab1 and gab2 and their association with shp-2, grb2, and PI3 kinase. Biochemical and Biophysical Research Communications. 277: 195-9. PMID 11027663 DOI: 10.1006/Bbrc.2000.3662  0.561
2000 Balduini A, Braun SE, Cornetta K, Lyman S, Broxmeyer HE. Comparative effects of retroviral-mediated gene transfer into primary human stromal cells of Flt3-ligand, interleukin 3 and GM-CSF on production of cord blood progenitor cells in long-term culture. Stem Cells (Dayton, Ohio). 37-49. PMID 11012147 DOI: 10.1002/Stem.5530160807  0.445
2000 Wang LS, Liu HJ, Xia ZB, Broxmeyer HE, Lu L. Expression and activation of caspase-3/CPP32 in CD34(+) cord blood cells is linked to apoptosis after growth factor withdrawal. Experimental Hematology. 28: 907-15. PMID 10989191 DOI: 10.1016/S0301-472X(00)00485-9  0.398
2000 Dai MS, Heinrich MC, Broxmeyer HE, Lu L. Enhancing effects of co-transduction of both human erythropoietin receptor and c-kit cDNAs into hematopoietic stem/progenitor cells from cord blood on proliferation and differentiation of erythroid progenitors Cytokines, Cellular and Molecular Therapy. 6: 1-8. PMID 10976533 DOI: 10.1080/13684730050515859  0.487
2000 Zhang S, Fukuda S, Lee Y, Hangoc G, Cooper S, Spolski R, Leonard WJ, Broxmeyer HE. Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling. The Journal of Experimental Medicine. 192: 719-28. PMID 10974037 DOI: 10.1084/Jem.192.5.719  0.626
2000 Dai MS, Ge Y, Xia ZB, Broxmeyer HE, Lu L. Introduction of human erythropoietin receptor complementary DNA by retrovirus-mediated gene transfer into murine embryonic stem cells enhances erythropoiesis in developing embryoid bodies. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 6: 395-407. PMID 10917575 DOI: 10.1016/S1083-8791(00)70016-4  0.489
2000 Lu L, Wang LS, Cooper RJ, Liu HJ, Turner K, Weich N, Broxmeyer HE. Suppressive effects of TNF-alpha, TGF-beta1, and chemokines on megakaryocytic colony formation in CD34+ cells derived from umbilical cord blood compared with mobilized peripheral blood and bone marrow. Journal of Hematotherapy & Stem Cell Research. 9: 195-204. PMID 10813532 DOI: 10.1089/152581600319405  0.448
2000 Braun SE, Chen K, Foster RG, Kim CH, Hromas R, Kaplan MH, Broxmeyer HE, Cornetta K. The CC chemokine CK beta-11/MIP-3 beta/ELC/Exodus 3 mediates tumor rejection of murine breast cancer cells through NK cells. Journal of Immunology (Baltimore, Md. : 1950). 164: 4025-31. PMID 10754294 DOI: 10.4049/Jimmunol.164.8.4025  0.354
2000 Xiao M, Luo Z, Mantel C, Broxmeyer HE, Lu L. Transduction of human IL-9 receptor cDNA into TF1 cells induces IL-9 dependency and erythroid differentiation. Journal of Hematotherapy & Stem Cell Research. 9: 77-82. PMID 10738974 DOI: 10.1089/152581600319649  0.384
2000 Martiney JA, Sherry B, Metz CN, Espinoza M, Ferrer AS, Calandra T, Broxmeyer HE, Bucala R. Macrophage migration inhibitory factor release by macrophages after ingestion of Plasmodium chabaudi-infected erythrocytes: possible role in the pathogenesis of malarial anemia. Infection and Immunity. 68: 2259-67. PMID 10722628 DOI: 10.1128/Iai.68.4.2259-2267.2000  0.336
2000 Kim CH, Hangoc G, Cooper S, Helgason CD, Yew S, Humphries RK, Krystal G, Broxmeyer HE. Altered responsiveness to chemokines due to targeted disruption of SHIP. The Journal of Clinical Investigation. 104: 1751-9. PMID 10606629 DOI: 10.1172/Jci7310  0.472
2000 Thomson BG, Robertson KA, Gowan D, Heilman D, Broxmeyer HE, Emanuel D, Kotylo P, Brahmi Z, Smith FO. Analysis of engraftment, graft-versus-host disease, and immune recovery following unrelated donor cord blood transplantation Blood. 96: 2703-2711. DOI: 10.1182/Blood.V96.8.2703.H8002703_2703_2711  0.393
2000 Dai M, Mantel CR, Xia Z, Broxmeyer HE, Lu L. An expansion phase precedes terminal erythroid differentiation of hematopoietic progenitor cells from cord blood in vitro and is associated with up-regulation of cyclin E and cyclin-dependent kinase 2 Blood. 96: 3985-3987. DOI: 10.1182/Blood.V96.12.3985.H8003985_3985_3987  0.454
2000 Hromas R, Cripe L, Hangoc G, Cooper S, Broxmeyer HE. The Exodus subfamily of CC chemokines inhibits the proliferation of chronic myelogenous leukemia progenitors Blood. 95: 1506-1508. DOI: 10.1182/Blood.V95.4.1506.004K41_1506_1508  0.425
2000 Broxmeyer HE, Cooper S, Hangoc G, Kim CH. Tissue-specific transgene expression of chemokine ckβ-11 is coincident with enhanced levels of cycling macrophage progenitors in spleen Experimental Hematology. 28: 99-100. DOI: 10.1016/S0301-472X(00)00396-9  0.382
2000 Kaplan MH, Cooper S, Hangoc G, Broxmeyer HE. Regulation of myeloid progenitor cell proliferation by STAT4- and STAT6-dependent CD4+ t helper cell populations Experimental Hematology. 28: 99. DOI: 10.1016/S0301-472X(00)00395-7  0.53
1999 Reid S, Broxmeyer HE. The effects of GM-CSF, steel factor and MIP-1α on the expression and activation of Cdc25A phosphatase in mo7e cells Cytokines, Cellular and Molecular Therapy. 5: 129-138. PMID 10641570  0.322
1999 Ritchie A, Broxmeyer HE. Suppression of p53-mediated growth factor withdrawal-induced apoptosis in the myeloid compartment by hematopoietic cytokines: an overview of hematopoiesis and apoptosis with a presentation of thrombopoietin and the M07E cell line as a model system. Critical Reviews in Oncology/Hematology. 31: 169-91. PMID 10532194 DOI: 10.1016/S1040-8428(99)00018-9  0.33
1999 Lu L, Heinrich MC, Wang LS, Dai MS, Zigler AJ, Chai L, Broxmeyer HE. Retroviral-mediated gene transduction of c-kit into single hematopoietic progenitor cells from cord blood enhances erythroid colony formation and decreases sensitivity to inhibition by tumor necrosis factor-α and transforming growth factor-β1 Blood. 94: 2319-2332. PMID 10498604 DOI: 10.1182/Blood.V94.7.2319.419K14_2319_2332  0.48
1999 Braun SE, Chen K, Blazar BR, Orchard PJ, Sledge G, Robertson MJ, Broxmeyer HE, Cornetta K. Flt3 ligand antitumor activity in a murine breast cancer model: a comparison with granulocyte-macrophage colony-stimulating factor and a potential mechanism of action. Human Gene Therapy. 10: 2141-51. PMID 10498246 DOI: 10.1089/10430349950017130  0.334
1999 Kim CH, Broxmeyer HE. SLC/Exodus2/6Ckine/TCA4 induces chemotaxis of hematopoietic progenitor cells: Differential activity of ligands of CCR7, CXCR3, or CXCR4 in chemotaxis vs. suppression of progenitor proliferation Journal of Leukocyte Biology. 66: 455-461. PMID 10496316 DOI: 10.1002/Jlb.66.3.455  0.422
1999 Kim CH, Qu CK, Hangoc G, Cooper S, Anzai N, Feng GS, Broxmeyer HE. Abnormal chemokine-induced responses of immature and mature hematopoietic cells from motheaten mice implicate the protein tyrosine phosphatase SHP-1 in chemokine responses. The Journal of Experimental Medicine. 190: 681-90. PMID 10477552 DOI: 10.1084/Jem.190.5.681  0.468
1999 Gotoh A, Reid S, Miyazawa K, Broxmeyer HE. SDF-1 suppresses cytokine-induced adhesion of human haemopoietic progenitor cells to immobilized fibronectin. British Journal of Haematology. 106: 171-4. PMID 10444182 DOI: 10.1046/J.1365-2141.1999.01517.X  0.485
1999 Broxmeyer HE, Kim CH. Regulation of hematopoiesis in a sea of chemokine family members with a plethora of redundant activities Experimental Hematology. 27: 1113-1123. PMID 10390186 DOI: 10.1016/S0301-472X(99)00045-4  0.512
1999 Broxmeyer HE, Cooper S, Hangoc G, Gao JL, Murphy PM. Dominant myelopoietic effector functions mediated by chemokine receptor CCR1. The Journal of Experimental Medicine. 189: 1987-92. PMID 10377195 DOI: 10.1084/Jem.189.12.1987  0.375
1999 Mantel CR, Balduini A, Broxmeyer HE. A human factor-dependent cell line simulates cobblestone formation under human bone marrow stromal cells in vitro. Annals of the New York Academy of Sciences. 872: 399-401. PMID 10372144 DOI: 10.1111/J.1749-6632.1999.Tb08486.X  0.41
1999 Kim CH, Broxmeyer HE. Thrombopoietin and interleukin-3 are chemotactic and chemokinetic chemoattractants for a factor-dependent hematopoietic progenitor cell line Annals of the New York Academy of Sciences. 872: 395-398. PMID 10372143 DOI: 10.1111/J.1749-6632.1999.Tb08485.X  0.432
1999 Broxmeyer HE, Kim CH, Cooper SH, Hangoc G, Hromas R, Pelus LM. Effects of CC, CXC, C, and CX3C chemokines on proliferation of myeloid progenitor cells, and insights into SDF-1-induced chemotaxis of progenitors Annals of the New York Academy of Sciences. 872: 142-163. PMID 10372118 DOI: 10.1111/J.1749-6632.1999.Tb08460.X  0.452
1999 Orlic D, Girard LJ, Anderson SM, Barrette S, Broxmeyer HE, Bodine DM. Amphotropic retrovirus transduction of hematopoietic stem cells Annals of the New York Academy of Sciences. 872: 115-124. PMID 10372116 DOI: 10.1111/J.1749-6632.1999.Tb08458.X  0.432
1999 Kim CH, Pelus LM, Appelbaum E, Johanson K, Anzai N, Broxmeyer HE. CCR7 ligands, SLC/6Ckine/Exodus2/TCA4 and CKbeta-11/MIP-3beta/ELC, are chemoattractants for CD56(+)CD16(-) NK cells and late stage lymphoid progenitors. Cellular Immunology. 193: 226-35. PMID 10222066 DOI: 10.1006/Cimm.1999.1483  0.421
1999 Zhang S, Mantel C, Broxmeyer HE. Flt3 signaling involves tyrosyl-phosphorylation of SHP-2 and SHIP and their association with Grb2 and Shc in Baf3/Flt3 cells. Journal of Leukocyte Biology. 65: 372-80. PMID 10080542 DOI: 10.1002/Jlb.65.3.372  0.588
1999 Ritchie A, Braun SE, He J, Broxmeyer HE. Thrombopoietin-induced conformational change in p53 lies downstream of the p44/p42 mitogen activated protein kinase cascade in the human growth factor-dependent cell line M07e Oncogene. 18: 1465-1477. PMID 10050883 DOI: 10.1038/Sj.Onc.1202439  0.384
1999 Hromas R, Broxmeyer HE, Kim C, Nakshatri H, Christopherson K, Azam M, Hou YH. Cloning of BRAK, a novel divergent CXC chemokine preferentially expressed in normal versus malignant cells. Biochemical and Biophysical Research Communications. 255: 703-6. PMID 10049774 DOI: 10.1006/Bbrc.1999.0257  0.369
1999 Zhang S, Broxmeyer HE. p85 subunit of PI3 kinase does not bind to human Flt3 receptor, but associates with SHP2, SHIP, and a tyrosine-phosphorylated 100-kDa protein in Flt3 ligand-stimulated hematopoietic cells. Biochemical and Biophysical Research Communications. 254: 440-5. PMID 9918857 DOI: 10.1006/Bbrc.1998.9959  0.541
1999 Kim CH, Broxmeyer HE. Chemokines: Signal lamps for trafficking of T and B cells for development and effector function Journal of Leukocyte Biology. 65: 6-15. PMID 9886241 DOI: 10.1002/Jlb.65.1.6  0.408
1999 Youn B, Kim CH, Smith FO, Broxmeyer HE. TECK, an Efficacious Chemoattractant for Human Thymocytes, Uses GPR-9-6/CCR9 as a Specific Receptor Blood. 94: 2533-2536. DOI: 10.1182/Blood.V94.7.2533.419K37_2533_2536  0.44
1999 Shibayama H, Anzai N, Braun SE, Fukuda S, Mantel C, Broxmeyer HE. H-Ras Is Involved in the Inside-out Signaling Pathway of Interleukin-3–Induced Integrin Activation Blood. 93: 1540-1548. DOI: 10.1182/Blood.V93.5.1540.405K10_1540_1548  0.398
1999 Reid S, Ritchie A, Boring L, Gosling J, Cooper S, Hangoc G, Charo IF, Broxmeyer HE. Enhanced Myeloid Progenitor Cell Cycling and Apoptosis in Mice Lacking the Chemokine Receptor, CCR2 Blood. 93: 1524-1533. DOI: 10.1182/Blood.V93.5.1524.405K07_1524_1533  0.454
1999 Mantel C, Braun SE, Reid S, Henegariu O, Liu L, Hangoc G, Broxmeyer HE. p21cip-1/waf-1 Deficiency Causes Deformed Nuclear Architecture, Centriole Overduplication, Polyploidy, and Relaxed Microtubule Damage Checkpoints in Human Hematopoietic Cells Blood. 93: 1390-1398. DOI: 10.1182/Blood.V93.4.1390.404K25_1390_1398  0.327
1999 Anzai N, Gotoh A, Shibayama H, Broxmeyer HE. Modulation of Integrin Function in Hematopoietic Progenitor Cells by CD43 Engagement: Possible Involvement of Protein Tyrosine Kinase and Phospholipase C-γ Blood. 93: 3317-3326. DOI: 10.1182/Blood.V93.10.3317.410K12_3317_3326  0.431
1998 Qu CK, Yu WM, Azzarelli B, Cooper S, Broxmeyer HE, Feng GS. Biased suppression of hematopoiesis and multiple developmental defects in chimeric mice containing Shp-2 mutant cells. Molecular and Cellular Biology. 18: 6075-82. PMID 9742124 DOI: 10.1128/Mcb.18.10.6075  0.441
1998 Shibayama H, Anzai N, Ritchie A, Zhang S, Mantel C, Broxmeyer HE. Interleukin-3 and Flt3-ligand induce adhesion of Baf3/Flt3 precursor B-lymphoid cells to fibronectin via activation of VLA-4 and VLA-5. Cellular Immunology. 187: 27-33. PMID 9682000 DOI: 10.1006/Cimm.1998.1318  0.63
1998 Youn BS, Zhang S, Broxmeyer HE, Antol K, Fraser MJ, Hangoc G, Kwon BS. Isolation and characterization of LMC, a novel lymphocyte and monocyte chemoattractant human CC chemokine, with myelosuppressive activity. Biochemical and Biophysical Research Communications. 247: 217-22. PMID 9642106 DOI: 10.1006/Bbrc.1998.8762  0.526
1998 Braun SE, Mantel C, Rosenthal M, Cooper S, Liu L, Robertson KA, Hromas R, Broxmeyer HE. A positive effect of p21cip1/waf1 in the colony formation from murine myeloid progenitor cells as assessed by retroviral-mediated gene transfer. Blood Cells, Molecules & Diseases. 24: 138-48. PMID 9628851 DOI: 10.1006/Bcmd.1998.0181  0.491
1998 Ge Y, Li ZH, Marshall MS, Broxmeyer HE, Lu L. Involvement of H-ras in erythroid differentiation of TF1 and human umbilical cord blood CD34 cells. Blood Cells, Molecules & Diseases. 24: 124-36; discussion 1. PMID 9628849 DOI: 10.1006/Bcmd.1998.0179  0.426
1998 Ge Y, Broxmeyer HE, Lu L. Leukemia inhibitory factor and steel factor regulate Tie message stability in CD34+ cells from human umbilical cord blood In Vivo. 12: 149-153. PMID 9627795  0.37
1998 Orlic D, Girard LJ, Anderson SM, Pyle LC, Yoder MC, Broxmeyer HE, Bodine DM. Identification of human and mouse hematopoietic stem cell populations expressing high levels of mRNA encoding retrovirus receptors Blood. 91: 3247-3254. PMID 9558380 DOI: 10.1182/Blood.V91.9.3247  0.474
1998 Youn BS, Zhang SM, Broxmeyer HE, Cooper S, Antol K, Fraser M, Kwon BS. Characterization of CKbeta8 and CKbeta8-1: two alternatively spliced forms of human beta-chemokine, chemoattractants for neutrophils, monocytes, and lymphocytes, and potent agonists at CC chemokine receptor 1. Blood. 91: 3118-26. PMID 9558365  0.503
1998 Porcu P, Gaddy J, Broxmeyer HE. Alloantigen-induced unresponsiveness in cord blood T lymphocytes is associated defective activation of Ras Proceedings of the National Academy of Sciences of the United States of America. 95: 4538-4543. PMID 9539773 DOI: 10.1073/Pnas.95.8.4538  0.361
1998 Broxmeyer HE, Orazi A, Hague NL, Sledge GW, Rasmussen H, Gordon MS. Myeloid progenitor cell proliferation and mobilization effects of BB10010, a genetically engineered variant of human macrophage inflammatory protein-1alpha, in a phase I clinical trial in patients with relapsed/refractory breast cancer. Blood Cells, Molecules & Diseases. 24: 14-30. PMID 9516378 DOI: 10.1006/Bcmd.1998.0167  0.492
1998 Lu L, Li ZH, He J, Ge Y, Rice S, Broxmeyer HE. Transduction of recombinant human erythropoietin receptor cDNA into daughter progenitors derived from single CD34(3+) cord blood cells changes the differentiation profile of daughter progenitors. Journal of Leukocyte Biology. 63: 389-94. PMID 9500528 DOI: 10.1002/Jlb.63.3.389  0.515
1998 Kim CH, Broxmeyer HE. In vitro behavior of hematopoietic progenitor cells under the influence of chemoattractants: Stromal cell-derived factor-1, steel factor, and the bone marrow environment Blood. 91: 100-110. PMID 9414273 DOI: 10.1182/Blood.V91.1.100.100_100_110  0.517
1998 Boring L, Gosling J, Chensue SW, Kunkel SL, Farese RV, Broxmeyer HE, Charo IF. Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice. The Journal of Clinical Investigation. 100: 2552-61. PMID 9366570 DOI: 10.1172/Jci119798  0.375
1998 Haneline L, Broxmeyer H, Cooper S, Hangoc G, Carreau M, Buchwald M, Clapp D. Multiple Inhibitory Cytokines Induce Deregulated Progenitor Growth and Apoptosis in Hematopoietic Cells from Fac -/- Mice • 765 Pediatric Research. 43: 133-133. DOI: 10.1203/00006450-199804001-00786  0.431
1998 Youn BS, Zhang SM, Broxmeyer HE, Cooper S, Antol K, Fraser M, Kwon BS. Characterization of CKβ8 and CKβ8-1: Two Alternatively Spliced Forms of Human β-Chemokine, Chemoattractants for Neutrophils, Monocytes, and Lymphocytes, and Potent Agonists at CC Chemokine Receptor 1 Blood. 91: 3118-3126. DOI: 10.1182/Blood.V91.9.3118.3118_3118_3126  0.351
1998 Kim CH, Pelus LM, White JR, Broxmeyer HE. Differential Chemotactic Behavior of Developing T Cells in Response to Thymic Chemokines Blood. 91: 4434-4443. DOI: 10.1182/Blood.V91.12.4434  0.358
1998 Haneline LS, Broxmeyer HE, Cooper S, Hangoc G, Carreau M, Buchwald M, Clapp DW. Multiple Inhibitory Cytokines Induce Deregulated Progenitor Growth and Apoptosis in Hematopoietic Cells From Fac−/− Mice Blood. 91: 4092-4098. DOI: 10.1182/Blood.V91.11.4092  0.44
1997 Youn BS, Zhang SM, Lee EK, Park DH, Broxmeyer HE, Murphy PM, Locati M, Pease JE, Kim KK, Antol K, Kwon BS. Molecular cloning of leukotactin-1: a novel human beta-chemokine, a chemoattractant for neutrophils, monocytes, and lymphocytes, and a potent agonist at CC chemokine receptors 1 and 3. Journal of Immunology (Baltimore, Md. : 1950). 159: 5201-5. PMID 9548457  0.517
1997 Gotoh A, Ritchie A, Takahira H, Broxmeyer HE. Thrombopoietin and erythropoietin activate inside-out signaling of integrin and enhance adhesion to immobilized fibronectin in human growth-factor-dependent hematopoietic cells Annals of Hematology. 75: 207-213. PMID 9433377 DOI: 10.1007/S002770050344  0.46
1997 Broxmeyer HE, Mantel CR, Aronica SM, Kaushansky K, Griffin, Fibbe WE. Biology and mechanisms of action of synergistically stimulated myeloid progenitor cell proliferation and suppression by chemokines Stem Cells. 15: 69-78. PMID 9368327 DOI: 10.1002/Stem.5530150811  0.447
1997 Gaddy J, Broxmeyer HE. Cord blood CD16+56- cells with low lytic activity are possible precursors of mature natural killer cells Cellular Immunology. 180: 132-142. PMID 9341743 DOI: 10.1006/Cimm.1997.1175  0.427
1997 Ge Y, Li ZH, Yung YP, Ratzkin BJ, Broxmeyer HE, Lu L. Up-regulation of Tie gene expression by leukemia inhibitory factor and steel factor in CD34+ cells from human umbilical cord blood. Journal of Leukocyte Biology. 62: 510-6. PMID 9335322 DOI: 10.1002/jlb.62.4.510  0.413
1997 Gao JL, Wynn TA, Chang Y, Lee EJ, Broxmeyer HE, Cooper S, Tiffany HL, Westphal H, Kwon-Chung J, Murphy PM. Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2 cytokine balance in mice lacking CC chemokine receptor 1 Journal of Experimental Medicine. 185: 1959-1968. PMID 9166425 DOI: 10.1084/Jem.185.11.1959  0.395
1997 Tian M, Broxmeyer HE, Fan Y, Lai Z, Zhang S, Aronica S, Cooper S, Bigsby RM, Steinmetz R, Engle SJ, Mestek A, Pollock JD, Lehman MN, Jansen HT, Ying M, et al. Altered hematopoiesis, behavior, and sexual function in mu opioid receptor-deficient mice. The Journal of Experimental Medicine. 185: 1517-22. PMID 9126934 DOI: 10.1084/jem.185.8.1517  0.483
1997 Takahira H, Gotoh A, Ritchie A, Broxmeyer HE. Steel factor enhances integrin-mediated tyrosine phosphorylation of focal adhesion kinase (pp125(FAK)) and paxillin Blood. 89: 1574-1584. PMID 9057639 DOI: 10.1182/Blood.V89.5.1574  0.377
1997 Gotoh A, Broxmeyer HE. The function of BCR/ABL and related proto-oncogenes Current Opinion in Hematology. 4: 3-11. PMID 9050373 DOI: 10.1097/00062752-199704010-00002  0.334
1997 Broxmeyer HE, Cooper S. High-efficiency recovery of immature haematopoietic progenitor cells with extensive proliferative capacity from human cord blood cryopreserved for 10 years Clinical and Experimental Immunology, Supplement. 107: 45-53. PMID 9020936  0.392
1997 Ritchie A, Gotoh A, Gaddy J, Braun SE, Broxmeyer HE. Thrombopoietin Upregulates the Promoter Conformation of p53 in a Proliferation-Independent Manner Coincident With a Decreased Expression of Bax: Potential Mechanisms for Survival Enhancing Effects Blood. 90: 4394-4402. DOI: 10.1182/Blood.V90.11.4394.4394_4394_4402  0.383
1997 Hromas R, Gray PW, Chantry D, Godiska R, Krathwohl M, Fife K, Bell GI, Takeda J, Aronica S, Gordon M, Cooper S, Broxmeyer HE, Klemsz MJ. Cloning and Characterization of Exodus, a Novel β-Chemokine Blood. 89: 3315-3322. DOI: 10.1182/Blood.V89.9.3315  0.412
1996 Aronica SM, Broxmeyer HE. Advances in understanding the postreceptor mechanisms of action of GM- CSF, G-CSF, and steel factor Current Opinion in Hematology. 3: 185-190. PMID 9372074 DOI: 10.1097/00062752-199603030-00004  0.373
1996 Broxmeyer HE, Cooper S, Cacalano G, Hague NL, Bailish E, Moore MW. Involvement of interleukin (IL) 8 receptor in negative regulation of myeloid progenitor cells in vivo: Evidence from mice lacking the murine IL-8 receptor homologue Journal of Experimental Medicine. 184: 1825-1832. PMID 8920870 DOI: 10.1084/Jem.184.5.1825  0.427
1996 Takahira H, Lyman SD, Broxmeyer HE. Flt3 ligand prolongs survival of CD34+++ human umbilical cord blood myeloid progenitors in serum-depleted culture medium Annals of Hematology. 72: 131-135. PMID 8766254 DOI: 10.1007/S002770050150  0.471
1996 Horie M, Sakamoto KM, Broxmeyer HE. Regulation of egr-1 gene expression by retinoic acid in a human growth factor-dependent cell line International Journal of Hematology. 63: 303-309. PMID 8762813 DOI: 10.1016/0925-5710(96)00451-3  0.32
1996 Lu L, Li ZH, Broxmeyer HE. Recovery and characterization of CD34+ cord blood cells after cryopreservation In Vivo. 10: 229-232. PMID 8744805  0.37
1996 Ritchie A, Vadhan-Raj S, Broxmeyer HE. Thrombopoietin suppresses apoptosis and behaves as a survival factor for the human growth factor-dependent cell line, M07e Stem Cells. 14: 330-336. PMID 8724699 DOI: 10.1002/Stem.140330  0.457
1996 Broxmeyer HE. Primitive hematopoietic stem and progenitor cells in human umbilical cord blood: an alternative source of transplantable cells Cancer Treatment and Research. 84: 139-148. PMID 8724629 DOI: 10.1007/978-1-4613-1261-1_7  0.519
1996 Xiao M, Li ZH, McMahel J, Broxmeyer HE, Lu L. Inhibitory effects of interleukin 12 on retroviral gene transduction into CD34 cord blood myeloid progenitors mediated by induction of tumor necrosis factor-alpha. Journal of Hematotherapy. 5: 171-7. PMID 8723796 DOI: 10.1089/Scd.1.1996.5.171  0.389
1996 Broxmeyer HE, Cooper S, Li ZH, Lu L, Sarris A, Wang MH, Chang MS, Donner DB, Leonard EJ. Macrophage-stimulating protein, a ligand for the RON receptor protein tyrosine kinase, suppresses myeloid progenitor cell proliferation and synergizes with vascular endothelial cell growth factor and members of the chemokine family. Annals of Hematology. 73: 1-9. PMID 8695717 DOI: 10.1007/S002770050192  0.507
1996 Lu L, Shen RN, Broxmeyer HE. Stem cells from bone marrow, umbilical cord blood and peripheral blood for clinical application: Current status and future application Critical Reviews in Oncology/Hematology. 22: 61-78. PMID 8679101 DOI: 10.1016/1040-8428(96)88370-3  0.463
1996 Taylor GA, Carballo E, Lee DM, Lai WS, Thompson MJ, Patel DD, Schenkman DI, Gilkeson GS, Broxmeyer HE, Haynes BF, Blackshear PJ. A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency. Immunity. 4: 445-54. PMID 8630730 DOI: 10.1016/S1074-7613(00)80411-2  0.308
1996 Broxmeyer HE, Cooper S, Etienne-Julan M, Wang XS, Ponnazhagan S, Braun S, Lu L, Srivastava A. Cord blood transplantation and the potential for gene therapy. Gene transduction using a recombinant adeno-associated viral vector. Annals of the New York Academy of Sciences. 770: 105-15. PMID 8597353 DOI: 10.1111/J.1749-6632.1995.Tb31048.X  0.436
1996 Broxmeyer HE, Cooper S, Li ZH, Lu L, Song HY, Kwon BS, Warren RE, Donner DB. Myeloid progenitor cell regulatory effects of vascular endothelial cell growth factor. International Journal of Hematology. 62: 203-15. PMID 8589366 DOI: 10.1016/0925-5710(95)00412-2  0.456
1996 Lu L, Ge Y, Li ZH, Freie B, Clapp DW, Broxmeyer HE. CD34 stem/progenitor cells purified from cryopreserved normal cord blood can be transduced with high efficiency by a retroviral vector and expanded ex vivo with stable integration and expression of Fanconi anemia complementation C gene. Cell Transplantation. 4: 493-503. PMID 8520833 DOI: 10.1016/0963-6897(95)00041-U  0.49
1996 Broxmeyer HE, Cooper S, Hague N, Benninger L, Sarris A, Cornetta K, Vadhan-Raj S, Hendrie P, Mantel C. Human chemokines: enhancement of specific activity and effects in vitro on normal and leukemic progenitors and a factor-dependent cell line and in vivo in mice. Annals of Hematology. 71: 235-46. PMID 7492626 DOI: 10.1007/Bf01744373  0.498
1996 Mantel C, Luo Z, Canfield J, Braun S, Deng C, Broxmeyer H. Involvement of p21cip-1 and p27kip-1 in the molecular mechanisms of steel factor-induced proliferative synergy in vitro and of p21cip-1 in the maintenance of stem/progenitor cells in vivo Blood. 88: 3710-3719. DOI: 10.1182/Blood.V88.10.3710.Bloodjournal88103710  0.556
1996 Gotoh A, Takahira H, Mantel C, Litz-Jackson S, Boswell H, Broxmeyer H. Steel factor induces serine phosphorylation of Stat3 in human growth factor-dependent myeloid cell lines Blood. 88: 138-145. DOI: 10.1182/Blood.V88.1.138.Bloodjournal881138  0.411
1996 Lu L, Ge Y, Li Z, Keeble W, Kabat D, Bagby G, Broxmeyer H, Hoatlin M. Retroviral transfer of the recombinant human erythropoietin receptor gene into single hematopoietic stem/progenitor cells from human cord blood increases the number of erythropoietin-dependent erythroid colonies Blood. 87: 525-534. DOI: 10.1182/Blood.V87.2.525.Bloodjournal872525  0.5
1996 Cheng J, Baumhueter S, Cacalano G, Carver-Moore K, Thibodeaux H, Thomas R, Broxmeyer H, Cooper S, Hague N, Moore M, Lasky L. Hematopoietic defects in mice lacking the sialomucin CD34 Blood. 87: 479-490. DOI: 10.1182/blood.V87.2.479.bloodjournal872479  0.396
1996 Tauchi T, Damen J, Toyama K, Feng G, Broxmeyer H, Krystal G. Tyrosine 425 within the activated erythropoietin receptor binds Syp, reduces the erythropoietin required for Syp tyrosine phosphorylation, and promotes mitogenesis Blood. 87: 4495-4501. DOI: 10.1182/Blood.V87.11.4495.Bloodjournal87114495  0.363
1995 Risdon G, Gaddy J, Horie M, Broxmeyer HE. Alloantigen priming induces a state of unresponsiveness in human umbilical cord blood T cells Proceedings of the National Academy of Sciences of the United States of America. 92: 2413-2417. PMID 7892281 DOI: 10.1073/Pnas.92.6.2413  0.466
1995 Bellido T, Jilka RL, Boyce BF, Girasole G, Broxmeyer H, Dalrymple SA, Murray R, Manolagas SC. Regulation of interleukin-6, osteoclastogenesis, and bone mass by androgens. The role of the androgen receptor. The Journal of Clinical Investigation. 95: 2886-95. PMID 7769130 DOI: 10.1172/Jci117995  0.363
1995 Broxmeyer HE. Cord blood as an alternative source for stem and progenitor cell transplantation Current Opinion in Pediatrics. 7: 47-55. PMID 7728203 DOI: 10.1097/00008480-199502000-00010  0.443
1995 Broxmeyer HE. Growth factors and cord blood stem and progenitor cells Immunological Investigations. 24: 391-402. PMID 7713598 DOI: 10.3109/08820139509062787  0.441
1995 Broxmeyer HE. Questions to be answered regarding umbilical cord blood hematopoietic stem and progenitor cells and their use in transplantation Transfusion. 35: 694-702. PMID 7631412 DOI: 10.1046/J.1537-2995.1995.35895357903.X  0.424
1995 Hiett AK, Britton KA, Hague NL, Brown HL, Stehman FB, Broxmeyer HE. Comparison of hematopoietic progenitor cells in human umbilical cord blood collected from neonatal infants who are small and appropriate for gestational age. Transfusion. 35: 587-91. PMID 7631392 DOI: 10.1046/J.1537-2995.1995.35795357882.X  0.326
1995 Broxmeyer H. The cell cycle as therapeutic target. Cancer Investigation. 13: 617-24. PMID 7583713 DOI: 10.3109/07357909509024932  0.467
1995 Daly TJ, LaRosa GJ, Dolich S, Maione TE, Cooper S, Broxmeyer HE. High activity suppression of myeloid progenitor proliferation by chimeric mutants of interleukin 8 and platelet factor 4 Journal of Biological Chemistry. 270: 23282-23292. PMID 7559482 DOI: 10.1074/Jbc.270.40.23282  0.396
1995 Gaddy J, Risdon G, Broxmeyer HE. Cord blood natural killer cells are functionally and phenotypically immature but readily respond to interleukin-2 and interleukin-12 Journal of Interferon and Cytokine Research. 15: 527-536. PMID 7553222 DOI: 10.1089/Jir.1995.15.527  0.465
1995 Aronica SM, Mantel C, Gonin R, Marshall MS, Sarris A, Cooper S, Hague N, Zhang XF, Broxmeyer HE. Interferon-inducible protein 10 and macrophage inflammatory protein-1 alpha inhibit growth factor stimulation of Raf-1 kinase activity and protein synthesis in a human growth factor-dependent hematopoietic cell line. The Journal of Biological Chemistry. 270: 21998-2007. PMID 7545174 DOI: 10.1074/Jbc.270.37.21998  0.417
1995 Yip-Schneider MT, Horie M, Broxmeyer HE. Transcriptional induction of pim-1 protein kinase gene expression by interferon γ and posttranscriptional effects on costimulation with steel factor Blood. 85: 3494-3502. PMID 7540064 DOI: 10.1182/Blood.V85.12.3494.Bloodjournal85123494  0.396
1995 Tauchi T, Feng GS, Shen R, Hoatlin M, Bagby GC, Kabat D, Lu L, Broxmeyer HE. Involvement of SH2-containing phosphotyrosine phosphatase Syp in erythropoietin receptor signal transduction pathways. The Journal of Biological Chemistry. 270: 5631-5. PMID 7534299 DOI: 10.1074/Jbc.270.10.5631  0.39
1995 Bock TA, Orlic D, Dunbar CE, Broxmeyer HE, Bodine DM. Improved engraftment of human hematopoietic cells in severe combined immunodeficient (SCID) mice carrying human cytokine transgenes. The Journal of Experimental Medicine. 182: 2037-43. PMID 7500049 DOI: 10.1084/Jem.182.6.2037  0.458
1995 Li ZH, Broxmeyer HE, Lu L. Cryopreserved cord blood myeloid progenitor cells can serve as targets for retroviral-mediated gene transduction and gene-transduced progenitors can be cryopreserved and recovered Leukemia. 9. PMID 7475303  0.32
1995 Vadhan-Raj S, Broxmeyer H, Andreeff M, Bandres J, Buescher E, Benjamin R, Papadopoulos N, Burgess A, Patel S, Plager C. In vivo biologic effects of PIXY321, a synthetic hybrid protein of recombinant human granulocyte-macrophage colony-stimulating factor and interleukin-3 in cancer patients with normal hematopoiesis: a phase I study Blood. 86: 2098-2105. DOI: 10.1182/Blood.V86.6.2098.Bloodjournal8662098  0.341
1995 Miyazawa K, Williams D, Gotoh A, Nishimaki J, Broxmeyer H, Toyama K. Membrane-bound Steel factor induces more persistent tyrosine kinase activation and longer life span of c-kit gene-encoded protein than its soluble form Blood. 85: 641-649. DOI: 10.1182/Blood.V85.3.641.Bloodjournal853641  0.339
1995 Lu L, Ge Y, Li Z, Freie B, Clapp DW, Broxmeyer HE. CD34+++ Stem/Progenitor Cells Purified from Cryopreserved Normal Cord Blood can be Transduced with High Efficiency by a Retroviral Vector and Expanded Ex Vivo with Stable Integration and Expression of Fanconi Anemia Complementation C Gene Cell Transplantation. 4: 493-503. DOI: 10.1177/096368979500400510  0.32
1994 Risdon G, Gaddy J, Stehman FB, Broxmeyer HE. Proliferative and cytotoxic responses of human cord blood T lymphocytes following allogeneic stimulation. Cellular Immunology. 154: 14-24. PMID 8118883 DOI: 10.1006/Cimm.1994.1053  0.454
1994 Shen RN, Lu L, Young P, Shidnia H, Hornback NB, Broxmeyer HE. Influence of elevated temperature on natural killer cell activity, lymphokine-activated killer cell activity and lectin-dependent cytotoxicity of human umbilical cord blood and adult blood cells. International Journal of Radiation Oncology, Biology, Physics. 29: 821-6. PMID 8040029 DOI: 10.1016/0360-3016(94)90571-1  0.396
1994 Broxmeyer HE. Consequences of human stem cells taking up residence in sheep Journal of Clinical Investigation. 93: 919. PMID 7907605  0.331
1994 Mantel C, Miyazawa K, Broxmeyer HE. Physical characteristics and polymerization during iron saturation of lactoferrin, a myelopoietic regulatory molecule with suppressor activity Advances in Experimental Medicine and Biology. 357: 121-132. PMID 7762423 DOI: 10.1007/978-1-4615-2548-6_12  0.312
1994 Risdon G, Gaddy J, Broxmeyer HE. Allogeneic responses of human umbilical cord blood Blood Cells. 20: 566-572. PMID 7749122  0.335
1994 Orazi A, Braun SE, Broxmeyer HE. Commentary: Immunohistochemistry represents a useful tool to study human cell engraftment in SCID mice transplantation models Blood Cells. 20: 323-330. PMID 7749113  0.376
1994 Hendrie PC, Broxmeyer HE. Myeloid cell proliferation stimulated by steel factor is pertussis toxin sensitive and enhanced by cholera toxin International Journal of Immunopharmacology. 16: 547-560. PMID 7523318 DOI: 10.1016/0192-0561(94)90106-6  0.393
1994 Zhou SZ, Cooper S, Kang LY, Ruggieri L, Heimfeld S, Srivastava A, Broxmeyer HE. Adeno-associated virus 2-mediated high efficiency gene transfer into immature and mature subsets of hematopoietic progenitor cells in human umbilical cord blood. The Journal of Experimental Medicine. 179: 1867-75. PMID 7515101 DOI: 10.1084/Jem.179.6.1867  0.434
1994 Tauchi T, Boswell HS, Leibowitz D, Broxmeyer HE. Coupling between p210bcr-abl and Shc and Grb2 adaptor proteins in hematopoietic cells permits growth factor receptor-independent link to ras activation pathway Journal of Experimental Medicine. 179: 167-175. PMID 7505797 DOI: 10.1084/Jem.179.1.167  0.415
1994 Mantel C, Luo Z, Hendrie P, Broxmeyer HE. Steel factor and granulocyte-macrophage colony stimulating factor act together to enhance choline-lipid turnover during synergistically stimulated proliferation of the human factor dependent cell line, M07E. Biochemical and Biophysical Research Communications. 197: 978-84. PMID 7505579 DOI: 10.1006/Bbrc.1993.2575  0.353
1994 Vormoor J, Lapidot T, Pflumio F, Risdon G, Patterson B, Broxmeyer H, Dick J. Immature human cord blood progenitors engraft and proliferate to high levels in severe combined immunodeficient mice Blood. 83: 2489-2497. DOI: 10.1182/Blood.V83.9.2489.Bloodjournal8392489  0.499
1994 Miyazawa K, Toyama K, Gotoh A, Hendrie P, Mantel C, Broxmeyer H. Ligand-dependent polyubiquitination of c-kit gene product: a possible mechanism of receptor down modulation in M07e cells Blood. 83: 137-145. DOI: 10.1182/Blood.V83.1.137.137  0.33
1993 Mantel C, Kim YJ, Cooper S, Kwon B, Broxmeyer HE. Polymerization of murine macrophage inflammatory protein 1 alpha inactivates its myelosuppressive effects in vitro: the active form is a monomer. Proceedings of the National Academy of Sciences of the United States of America. 90: 2232-6. PMID 8460127 DOI: 10.1073/Pnas.90.6.2232  0.303
1993 Sarris AH, Broxmeyer HE, Wirthmueller U, Karasavvas N, Cooper S, Lu L, Krueger J, Ravetch JV. Human interferon-inducible protein 10: expression and purification of recombinant protein demonstrate inhibition of early human hematopoietic progenitors. The Journal of Experimental Medicine. 178: 1127-32. PMID 8350051 DOI: 10.1084/jem.178.3.1127  0.348
1993 Wu B, Shen RN, Wang WX, Broxmeyer HE, Lu L. Antitumor effect of interleukin 7 in combination with local hyperthermia in mice bearing B16a melanoma cells. Stem Cells (Dayton, Ohio). 11: 412-21. PMID 8241952 DOI: 10.1002/Stem.5530110508  0.355
1993 Vormoor J, Lapidot T, Pflumio F, Risdon G, Patterson B, Broxmeyer HE, Dick JE. High-level multilineage engraftment of human cord blood cells in SCID mice Journal of Hematotherapy. 2: 215-216. PMID 7921977 DOI: 10.1089/Scd.1.1993.2.215  0.394
1993 Broxmeyer HE, Carow CE. Characterization of cord blood stem/progenitor cells Journal of Hematotherapy. 2: 197-199. PMID 7921973 DOI: 10.1089/Scd.1.1993.2.197  0.422
1993 Kohli-Kumar M, Shahidi NT, Broxmeyer HE, Masterson M, Delaat C, Sambrano J, Morris C, Auerbach AD, Harris RE. Haemopoietic stem/progenitor cell transplant in Fanconi anaemia using HLA-matched sibling umbilical cord blood cells. British Journal of Haematology. 85: 419-22. PMID 7904176 DOI: 10.1111/J.1365-2141.1993.Tb03192.X  0.427
1993 Carow CE, Hangoc G, Broxmeyer HE. Human multipotential progenitor cells (CFU-GEMM) have extensive replating capacity for secondary CFU-GEMM: An effect enhanced by cord blood plasma Blood. 81: 942-949. PMID 7679010 DOI: 10.1182/Blood.V81.4.942.942  0.448
1993 Carow CE, Harrington MA, Broxmeyer HE. Detection of human myeloid progenitor cells in a murine background Experimental Hematology. 21: 66-69. PMID 7678088  0.309
1993 Lu L, Xiao M, Clapp DW, Li ZH, Broxmeyer HE. High efficiency retroviral mediated gene transduction into single isolated immature and replatable CD34(3+) hematopoietic stem/progenitor cells from human umbilical cord blood. The Journal of Experimental Medicine. 178: 2089-96. PMID 7504056 DOI: 10.1084/Jem.178.6.2089  0.533
1993 Hangoc G, Yin T, Cooper S, Schendel P, Yang Y, Broxmeyer H. In vivo effects of recombinant interleukin-11 on myelopoiesis in mice Blood. 81: 965-972. DOI: 10.1182/Blood.V81.4.965.Bloodjournal814965  0.467
1993 Lu L, Xiao M, Shen R, Grigsby S, Broxmeyer H. Enrichment, characterization, and responsiveness of single primitive CD34 human umbilical cord blood hematopoietic progenitors with high proliferative and replating potential Blood. 81: 41-48. DOI: 10.1182/Blood.V81.1.41.41  0.511
1992 Vadhan-Raj S, Broxmeyer HE, Hittelman WN, Papadopoulos NE, Chawla SP, Fenoglio C, Cooper S, Stephen Buescher E, Frenck RW, Hollan A, Perkins RC, Scheule RK, Gutterman JU, Salem P, Benjamin RS. Abrogating chemotherapy-induced myelosuppression by recombinant granulocyte-macrophage colony-stimulating factor in patients with sarcoma: Protection at the progenitor cell level Journal of Clinical Oncology. 10: 1266-1277. PMID 1634916 DOI: 10.1200/Jco.1992.10.8.1266  0.359
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