Bert L. Semler - Publications

Affiliations: 
University of California, Irvine, Irvine, CA 
Area:
Microbiology Biology

152 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Manjunath L, Oh S, Ortega P, Bouin A, Bournique E, Sanchez A, Martensen PM, Auerbach AA, Becker JT, Seldin M, Harris RS, Semler BL, Buisson R. APOBEC3B drives PKR-mediated translation shutdown and protects stress granules in response to viral infection. Nature Communications. 14: 820. PMID 36781883 DOI: 10.1038/s41467-023-36445-9  0.516
2022 Bouin A, Vu MN, Al-Hakeem A, Tran GP, Nguyen JHC, Semler BL. Enterovirus-Cardiomyocyte Interactions: Impact of Terminally Deleted Genomic RNAs on Viral and Host Functions. Journal of Virology. e0142622. PMID 36475766 DOI: 10.1128/jvi.01426-22  0.617
2020 Xu X, Holmes TC, Luo MH, Beier KT, Horwitz GD, Zhao F, Zeng W, Hui M, Semler BL, Sandri-Goldin RM. Viral Vectors for Neural Circuit Mapping and Recent Advances in Trans-synaptic Anterograde Tracers. Neuron. PMID 32755550 DOI: 10.1016/J.Neuron.2020.07.010  0.339
2020 Beckham SA, Matak MY, Belousoff MJ, Venugopal H, Shah N, Vankadari N, Elmlund H, Nguyen JHC, Semler BL, Wilce MCJ, Wilce JA. Structure of the PCBP2/stem-loop IV complex underlying translation initiation mediated by the poliovirus type I IRES. Nucleic Acids Research. PMID 32556302 DOI: 10.1093/Nar/Gkaa519  0.502
2020 Holmes AC, Zagnoli-Vieira G, Caldecott KW, Semler BL. Effects of TDP2/VPg Unlinkase Activity on Picornavirus Infections Downstream of Virus Translation. Viruses. 12. PMID 32023921 DOI: 10.3390/V12020166  0.701
2019 Holmes AC, Semler BL. Picornaviruses and RNA Metabolism: Local and Global Effects of Infection. Journal of Virology. PMID 31413128 DOI: 10.1128/Jvi.02088-17  0.683
2019 Bouin A, Gretteau PA, Wehbe M, Renois F, N'Guyen Y, Leveque N, Vu MN, Tracy S, Chapman NM, Bruneval P, Fornes P, Semler BL, Andreoletti L. Enterovirus Persistence in Cardiac Cells of Patients Suffering From Idiopathic Dilated Cardiomyopathy is Linked to 5' Terminal Genomic RNA-Deleted Viral Populations With Viral-Encoded Proteinase Activities. Circulation. PMID 30755025 DOI: 10.1161/Circulationaha.118.035966  0.49
2018 Ullmer W, Semler BL. Direct and Indirect Effects on Viral Translation and RNA Replication Are Required for AUF1 Restriction of Enterovirus Infections in Human Cells. Mbio. 9. PMID 30181254 DOI: 10.1128/Mbio.01669-18  0.628
2018 Flather D, Nguyen JHC, Semler BL, Gershon PD. Exploitation of nuclear functions by human rhinovirus, a cytoplasmic RNA virus. Plos Pathogens. 14: e1007277. PMID 30142213 DOI: 10.1371/Journal.Ppat.1007277  0.681
2018 Maciejewski S, Ullmer W, Semler BL. VPg unlinkase/TDP2 in cardiovirus infected cells: Re-localization and proteolytic cleavage. Virology. 516: 139-146. PMID 29353210 DOI: 10.1016/J.Virol.2018.01.010  0.549
2017 Lévêque N, Garcia M, Bouin A, Nguyen JHC, Tran GP, Andreoletti L, Semler BL. Functional consequences of RNA 5' terminal deletions on coxsackievirus B3 RNA replication and ribonucleoprotein complex formation. Journal of Virology. PMID 28539455 DOI: 10.1128/Jvi.00423-17  0.737
2016 Karginov TA, Pastor DP, Semler BL, Gomez CM. Mammalian Polycistronic mRNAs and Disease. Trends in Genetics : Tig. PMID 28012572 DOI: 10.1016/J.Tig.2016.11.007  0.316
2016 Ullmer W, Semler BL. Diverse Strategies Used by Picornaviruses to Escape Host RNA Decay Pathways. Viruses. 8. PMID 27999393 DOI: 10.3390/V8120335  0.686
2016 Flather D, Cathcart AL, Cruz C, Baggs E, Ngo T, Gershon PD, Semler BL. Generation of Recombinant Polioviruses Harboring RNA Affinity Tags in the 5' and 3' Noncoding Regions of Genomic RNAs. Viruses. 8. PMID 26861382 DOI: 10.3390/V8020039  0.888
2016 Wehbe M, Huguenin A, Leveque N, Semler BL, Hamze M, Andreoletti L, Bouin A. Construction of a subgenomic CV-B3 replicon expressing emerald green fluorescent protein to assess viral replication of a cardiotropic enterovirus strain in cultured human cells. Journal of Virological Methods. 230: 1-8. PMID 26800776 DOI: 10.1016/J.Jviromet.2016.01.005  0.489
2016 Flather D, Cathcart AL, Cruz C, Baggs E, Ngo T, Gershon PD, Semler BL. Generation of recombinant polioviruses harboring RNA affinity tags in the 5' and 3' noncoding regions of genomic RNAs Viruses. 8. DOI: 10.3390/v8020039  0.854
2015 Maciejewski S, Nguyen JH, Gómez-Herreros F, Cortés-Ledesma F, Caldecott KW, Semler BL. Divergent Requirement for a DNA Repair Enzyme during Enterovirus Infections. Mbio. 7. PMID 26715620 DOI: 10.1128/Mbio.01931-15  0.681
2015 Flather D, Semler BL. Picornaviruses and nuclear functions: targeting a cellular compartment distinct from the replication site of a positive-strand RNA virus. Frontiers in Microbiology. 6: 594. PMID 26150805 DOI: 10.3389/Fmicb.2015.00594  0.67
2015 Lévêque N, Semler BL. A 21st century perspective of poliovirus replication. Plos Pathogens. 11: e1004825. PMID 26042673 DOI: 10.1371/Journal.Ppat.1004825  0.484
2014 Tsai BP, Jimenez J, Lim S, Fitzgerald KD, Zhang M, Chuah CT, Axelrod H, Wilson L, Ong ST, Semler BL, Waterman ML. A novel Bcr-Abl-mTOR-eIF4A axis regulates IRES-mediated translation of LEF-1. Open Biology. 4: 140180. PMID 25392452 DOI: 10.1098/Rsob.140180  0.721
2014 Cathcart AL, Semler BL. Differential restriction patterns of mRNA decay factor AUF1 during picornavirus infections. The Journal of General Virology. 95: 1488-92. PMID 24722678 DOI: 10.1099/Vir.0.064501-0  0.809
2014 Spindler KR, Semler BL. In memoriam John J. Holland (1929-2013): a pioneer in molecular virology. Journal of Virology. 88: 5903-5. PMID 24623431 DOI: 10.1128/Jvi.00653-14  0.541
2014 Du X, Semler BL, Gomez CM. Revelations from a bicistronic calcium channel gene. Cell Cycle (Georgetown, Tex.). 13: 875-6. PMID 24552819 DOI: 10.4161/Cc.28199  0.494
2014 Chase AJ, Semler BL. Differential cleavage of IRES trans-acting factors (ITAFs) in cells infected by human rhinovirus. Virology. 449: 35-44. PMID 24418535 DOI: 10.1016/J.Virol.2013.10.030  0.863
2014 Chase AJ, Daijogo S, Semler BL. Inhibition of poliovirus-induced cleavage of cellular protein PCBP2 reduces the levels of viral RNA replication. Journal of Virology. 88: 3192-201. PMID 24371074 DOI: 10.1128/Jvi.02503-13  0.896
2014 Langereis MA, Feng Q, Nelissen FH, Virgen-Slane R, van der Heden van Noort GJ, Maciejewski S, Filippov DV, Semler BL, van Delft FL, van Kuppeveld FJ. Modification of picornavirus genomic RNA using 'click' chemistry shows that unlinking of the VPg peptide is dispensable for translation and replication of the incoming viral RNA. Nucleic Acids Research. 42: 2473-82. PMID 24243841 DOI: 10.1093/Nar/Gkt1162  0.892
2014 Cathcart AL, Baggs EL, Semler BL. Picornaviruses: Pathogenesis and Molecular Biology Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.00272-5  0.801
2013 Cathcart AL, Rozovics JM, Semler BL. Cellular mRNA decay protein AUF1 negatively regulates enterovirus and human rhinovirus infections. Journal of Virology. 87: 10423-34. PMID 23903828 DOI: 10.1128/Jvi.01049-13  0.839
2013 Fitzgerald KD, Semler BL. Poliovirus infection induces the co-localization of cellular protein SRp20 with TIA-1, a cytoplasmic stress granule protein. Virus Research. 176: 223-31. PMID 23830997 DOI: 10.1016/J.Virusres.2013.06.012  0.715
2013 Semler BL, Whelan SPJ. Methods to study RNA virus molecular biology Methods. 59: 165-166. PMID 23465704 DOI: 10.1016/J.Ymeth.2013.02.013  0.61
2013 Fitzgerald KD, Chase AJ, Cathcart AL, Tran GP, Semler BL. Viral proteinase requirements for the nucleocytoplasmic relocalization of cellular splicing factor SRp20 during picornavirus infections. Journal of Virology. 87: 2390-400. PMID 23255796 DOI: 10.1128/Jvi.02396-12  0.806
2012 Chase AJ, Semler BL. Viral subversion of host functions for picornavirus translation and RNA replication. Future Virology. 7: 179-191. PMID 23293659 DOI: 10.2217/Fvl.12.2  0.823
2012 Feng Q, Hato SV, Langereis MA, Zoll J, Virgen-Slane R, Peisley A, Hur S, Semler BL, van Rij RP, van Kuppeveld FJ. MDA5 detects the double-stranded RNA replicative form in picornavirus-infected cells. Cell Reports. 2: 1187-96. PMID 23142662 DOI: 10.1016/J.Celrep.2012.10.005  0.882
2012 Rozovics JM, Chase AJ, Cathcart AL, Chou W, Gershon PD, Palusa S, Wilusz J, Semler BL. Picornavirus modification of a host mRNA decay protein. Mbio. 3: e00431-12. PMID 23131833 DOI: 10.1128/Mbio.00431-12  0.88
2012 Virgen-Slane R, Rozovics JM, Fitzgerald KD, Ngo T, Chou W, van der Heden van Noort GJ, Filippov DV, Gershon PD, Semler BL. An RNA virus hijacks an incognito function of a DNA repair enzyme. Proceedings of the National Academy of Sciences of the United States of America. 109: 14634-9. PMID 22908287 DOI: 10.1073/Pnas.1208096109  0.861
2012 Chase AJ, Semler BL. Viral subversion of host functions for picornavirus translation and RNA replication Future Virology. 7: 179-191. DOI: 10.2217/fvl.12.2  0.81
2011 Huang C, Lokugamage KG, Rozovics JM, Narayanan K, Semler BL, Makino S. SARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavage. Plos Pathogens. 7: e1002433. PMID 22174690 DOI: 10.1371/Journal.Ppat.1002433  0.885
2011 Fitzgerald KD, Semler BL. Re-localization of cellular protein SRp20 during poliovirus infection: bridging a viral IRES to the host cell translation apparatus. Plos Pathogens. 7: e1002127. PMID 21779168 DOI: 10.1371/Journal.Ppat.1002127  0.844
2011 Daijogo S, Semler BL. Mechanistic intersections between picornavirus translation and RNA replication. Advances in Virus Research. 80: 1-24. PMID 21762819 DOI: 10.1016/B978-0-12-385987-7.00001-4  0.896
2011 Rozovics JM, Virgen-Slane R, Semler BL. Engineered picornavirus VPg-RNA substrates: analysis of a tyrosyl-RNA phosphodiesterase activity. Plos One. 6: e16559. PMID 21408223 DOI: 10.1371/Journal.Pone.0016559  0.877
2011 Huang C, Lokugamage KG, Rozovics JM, Narayanan K, Semler BL, Makino S. Alphacoronavirus transmissible gastroenteritis virus nsp1 protein suppresses protein translation in mammalian cells and in cell-free HeLa cell extracts but not in rabbit reticulocyte lysate. Journal of Virology. 85: 638-43. PMID 21047955 DOI: 10.1128/Jvi.01806-10  0.817
2010 Grainger L, Cicchini L, Rak M, Petrucelli A, Fitzgerald KD, Semler BL, Goodrum F. Stress-inducible alternative translation initiation of human cytomegalovirus latency protein pUL138. Journal of Virology. 84: 9472-86. PMID 20592073 DOI: 10.1128/Jvi.00855-10  0.752
2010 Brunner JE, Ertel KJ, Rozovics JM, Semler BL. Delayed kinetics of poliovirus RNA synthesis in a human cell line with reduced levels of hnRNP C proteins. Virology. 400: 240-7. PMID 20189623 DOI: 10.1016/J.Virol.2010.01.031  0.836
2010 Ertel KJ, Brunner JE, Semler BL. Mechanistic consequences of hnRNP C binding to both RNA termini of poliovirus negative-strand RNA intermediates. Journal of Virology. 84: 4229-42. PMID 20164237 DOI: 10.1128/Jvi.02198-09  0.877
2010 Brunner JE, Semler BL. Positive‐Strand RNA Virus Replication in Vertebrate Hosts Topley and Wilson's Microbiology and Microbial Infections. DOI: 10.1002/9780470688618.Taw0215  0.879
2009 Fitzgerald KD, Semler BL. Bridging IRES elements in mRNAs to the eukaryotic translation apparatus. Biochimica Et Biophysica Acta. 1789: 518-28. PMID 19631772 DOI: 10.1016/J.Bbagrm.2009.07.004  0.825
2009 Sean P, Nguyen JH, Semler BL. Altered interactions between stem-loop IV within the 5' noncoding region of coxsackievirus RNA and poly(rC) binding protein 2: effects on IRES-mediated translation and viral infectivity. Virology. 389: 45-58. PMID 19446305 DOI: 10.1016/J.Virol.2009.03.012  0.878
2008 Sean P, Nguyen JH, Semler BL. The linker domain of poly(rC) binding protein 2 is a major determinant in poliovirus cap-independent translation. Virology. 378: 243-53. PMID 18656221 DOI: 10.1016/J.Virol.2008.05.007  0.86
2008 Sean P, Semler BL. Coxsackievirus B RNA replication: lessons from poliovirus. Current Topics in Microbiology and Immunology. 323: 89-121. PMID 18357767 DOI: 10.1007/978-3-540-75546-3_5  0.901
2008 Semler BL, Waterman ML. IRES-mediated pathways to polysomes: nuclear versus cytoplasmic routes. Trends in Microbiology. 16: 1-5. PMID 18083033 DOI: 10.1016/J.Tim.2007.11.001  0.601
2008 Jang GM, Tanaka BS, Gutman GA, Goldin AL, Semler BL. Alternative polyadenylation signals in the 3' non-coding region of a voltage-gated potassium channel gene are major determinants of mRNA isoform expression. Gene. 408: 133-45. PMID 18077107 DOI: 10.1016/J.Gene.2007.10.029  0.734
2007 Perera R, Daijogo S, Walter BL, Nguyen JH, Semler BL. Cellular protein modification by poliovirus: the two faces of poly(rC)-binding protein. Journal of Virology. 81: 8919-32. PMID 17581994 DOI: 10.1128/Jvi.01013-07  0.892
2007 Bedard KM, Daijogo S, Semler BL. A nucleo-cytoplasmic SR protein functions in viral IRES-mediated translation initiation. The Embo Journal. 26: 459-67. PMID 17183366 DOI: 10.1038/Sj.Emboj.7601494  0.875
2006 Cornell CT, Semler BL. Gene Expression and Replication of Picornaviruses Reviews in Cell Biology and Molecular Medicine. DOI: 10.1002/3527600906.Mcb.200300167  0.809
2005 Brown DM, Cornell CT, Tran GP, Nguyen JH, Semler BL. An authentic 3' noncoding region is necessary for efficient poliovirus replication. Journal of Virology. 79: 11962-73. PMID 16140772 DOI: 10.1128/Jvi.79.18.11962-11973.2005  0.86
2005 Jimenez J, Jang GM, Semler BL, Waterman ML. An internal ribosome entry site mediates translation of lymphoid enhancer factor-1. Rna (New York, N.Y.). 11: 1385-99. PMID 16120831 DOI: 10.1261/Rna.7226105  0.737
2005 Semler BL. Resistance is futile. Nature Genetics. 37: 665-6. PMID 15990885 DOI: 10.1038/Ng0705-665  0.559
2005 Boerner JE, Lyle JM, Daijogo S, Semler BL, Schultz SC, Kirkegaard K, Richards OC. Allosteric effects of ligands and mutations on poliovirus RNA-dependent RNA polymerase. Journal of Virology. 79: 7803-11. PMID 15919933 DOI: 10.1128/Jvi.79.12.7803-7811.2005  0.878
2005 Kuznetsov YG, Daijogo S, Zhou J, Semler BL, McPherson A. Atomic force microscopy analysis of icosahedral virus RNA. Journal of Molecular Biology. 347: 41-52. PMID 15733916 DOI: 10.1016/J.Jmb.2005.01.006  0.881
2005 Brunner JE, Nguyen JH, Roehl HH, Ho TV, Swiderek KM, Semler BL. Functional interaction of heterogeneous nuclear ribonucleoprotein C with poliovirus RNA synthesis initiation complexes. Journal of Virology. 79: 3254-66. PMID 15731220 DOI: 10.1128/Jvi.79.6.3254-3266.2005  0.873
2004 Cornell CT, Brunner JE, Semler BL. Differential rescue of poliovirus RNA replication functions by genetically modified RNA polymerase precursors. Journal of Virology. 78: 13007-18. PMID 15542652 DOI: 10.1128/Jvi.78.23.13007-13018.2004  0.889
2004 Jang GM, Leong LE, Hoang LT, Wang PH, Gutman GA, Semler BL. Structurally distinct elements mediate internal ribosome entry within the 5'-noncoding region of a voltage-gated potassium channel mRNA. The Journal of Biological Chemistry. 279: 47419-30. PMID 15339906 DOI: 10.1074/Jbc.M405885200  0.755
2004 Bedard KM, Walter BL, Semler BL. Multimerization of poly(rC) binding protein 2 is required for translation initiation mediated by a viral IRES. Rna (New York, N.Y.). 10: 1266-76. PMID 15247434 DOI: 10.1261/Rna.7070304  0.873
2004 Semler BL. Poliovirus proves IRES-istible in vivo. The Journal of Clinical Investigation. 113: 1678-81. PMID 15199401 DOI: 10.1172/Jci22139  0.499
2004 Bedard KM, Semler BL. Regulation of picornavirus gene expression. Microbes and Infection / Institut Pasteur. 6: 702-13. PMID 15158778 DOI: 10.1016/J.Micinf.2004.03.001  0.838
2004 Cornell CT, Perera R, Brunner JE, Semler BL. Strand-specific RNA synthesis determinants in the RNA-dependent RNA polymerase of poliovirus. Journal of Virology. 78: 4397-407. PMID 15078921 DOI: 10.1128/Jvi.78.9.4397-4407.2004  0.887
2004 Brown DM, Kauder SE, Cornell CT, Jang GM, Racaniello VR, Semler BL. Cell-dependent role for the poliovirus 3' noncoding region in positive-strand RNA synthesis. Journal of Virology. 78: 1344-51. PMID 14722289 DOI: 10.1128/Jvi.78.3.1344-1351.2004  0.882
2003 Towner JS, Brown DM, Nguyen JH, Semler BL. Functional conservation of the hydrophobic domain of polypeptide 3AB between human rhinovirus and poliovirus. Virology. 314: 432-42. PMID 14517095 DOI: 10.1016/S0042-6822(03)00448-3  0.551
2002 Walter BL, Parsley TB, Ehrenfeld E, Semler BL. Distinct poly(rC) binding protein KH domain determinants for poliovirus translation initiation and viral RNA replication. Journal of Virology. 76: 12008-22. PMID 12414943 DOI: 10.1128/Jvi.76.23.12008-12022.2002  0.863
2002 Cornell CT, Semler BL. Subdomain specific functions of the RNA polymerase region of poliovirus 3CD polypeptide. Virology. 298: 200-13. PMID 12127783 DOI: 10.1006/Viro.2002.1481  0.829
2001 Teterina NL, Egger D, Bienz K, Brown DM, Semler BL, Ehrenfeld E. Requirements for assembly of poliovirus replication complexes and negative-strand RNA synthesis Journal of Virology. 75: 3841-3850. PMID 11264373 DOI: 10.1128/Jvi.75.8.3841-3850.2001  0.724
2000 Chapman NM, Ragland A, Leser JS, Höfling K, Willian S, Semler BL, Tracy S. A group B coxsackievirus/poliovirus 5' nontranslated region chimera can act as an attenuated vaccine strain in mice Journal of Virology. 74: 4047-4056. PMID 10756016 DOI: 10.1128/Jvi.74.9.4047-4056.2000  0.361
1999 Walter BL, Nguyen JH, Ehrenfeld E, Semler BL. Differential utilization of poly(rC) binding protein 2 in translation directed by picornavirus IRES elements. Rna (New York, N.Y.). 5: 1570-85. PMID 10606268 DOI: 10.1017/S1355838299991483  0.825
1999 Stewart SR, Semler BL. Pyrimidine-rich region mutations compensate for a stem-loop V lesion in the 5' noncoding region of poliovirus genomic RNA Virology. 264: 385-397. PMID 10562500 DOI: 10.1006/Viro.1999.9981  0.573
1999 Bell YC, Semler BL, Ehrenfeld E. Requirements for RNA replication of a poliovirus replicon by coxsackievirus B3 RNA polymerase Journal of Virology. 73: 9413-9421. PMID 10516050 DOI: 10.1128/Jvi.73.11.9413-9421.1999  0.648
1999 Parsley TB, Cornell CT, Semler BL. Modulation of the RNA binding and protein processing activities of poliovirus polypeptide 3CD by the viral RNA polymerase domain. The Journal of Biological Chemistry. 274: 12867-76. PMID 10212275 DOI: 10.1074/Jbc.274.18.12867  0.778
1998 Stewart SR, Semler BL. RNA structure adjacent to the attenuation determinant in the 5'-non-coding region influences poliovirus viability Nucleic Acids Research. 26: 5318-5326. PMID 9826754 DOI: 10.1093/Nar/26.23.5318  0.475
1998 Towner JS, Mazanet MM, Semler BL. Rescue of defective poliovirus RNA replication by 3AB-containing precursor polyproteins Journal of Virology. 72: 7191-7200. PMID 9696813 DOI: 10.1128/Jvi.72.9.7191-7200.1998  0.667
1998 Negulescu D, Leong LE, Chandy KG, Semler BL, Gutman GA. Translation initiation of a cardiac voltage-gated potassium channel by internal ribosome entry. The Journal of Biological Chemistry. 273: 20109-13. PMID 9685353 DOI: 10.1074/Jbc.273.32.20109  0.455
1998 Blair WS, Parsley TB, Bogerd HP, Towner JS, Semler BL, Cullen BR. Utilization of a mammalian cell-based RNA binding assay to characterize the RNA binding properties of picornavirus 3C proteinases Rna. 4: 215-225. PMID 9570321  0.604
1997 Todd S, Towner JS, Brown DM, Semler BL. Replication-competent picornaviruses with complete genomic RNA 3' noncoding region deletions Journal of Virology. 71: 8868-8874. PMID 9343250 DOI: 10.1128/Jvi.71.11.8868-8874.1997  0.697
1997 Parsley TB, Towner JS, Blyn LB, Ehrenfeld E, Semler BL. Poly (rC) binding protein 2 forms a ternary complex with the 5'-terminal sequences of poliovirus RNA and the viral 3CD proteinase Rna. 3: 1124-1134. PMID 9326487  0.621
1997 Blyn LB, Towner JS, Semler BL, Ehrenfeld E. Requirement of Poly(rC) binding protein 2 for translation of poliovirus RNA Journal of Virology. 71: 6243-6246. PMID 9223526 DOI: 10.1128/Jvi.71.8.6243-6246.1997  0.672
1997 Todd S, Towner JS, Semler BL. Translation and replication properties of the human rhinovirus genome in vivo and in vitro Virology. 229: 90-97. PMID 9123881 DOI: 10.1006/Viro.1996.8416  0.621
1997 Roehl HH, Parsley TB, Ho TV, Semler BL. Processing of a cellular polypeptide by 3CD proteinase is required for poliovirus ribonucleoprotein complex formation. Journal of Virology. 71: 578-85. PMID 8985386 DOI: 10.1128/Jvi.71.1.578-585.1997  0.702
1997 Stewart SR, Semler BL. RNA determinants of picornavirus cap-independent translation initiation Seminars in Virology. 8: 242-255. DOI: 10.1006/Smvy.1997.0127  0.718
1996 Towner JS, Ho TV, Semler BL. Determinants of membrane association for poliovirus protein 3AB. The Journal of Biological Chemistry. 271: 26810-8. PMID 8900162 DOI: 10.1074/Jbc.271.43.26810  0.402
1996 Blyn LB, Swiderek KM, Richards O, Stahl DC, Semler BL, Ehrenfeld E. Poly(rC) binding protein 2 binds to stem-loop IV of the poliovirus RNA 5′ noncoding region: Identification by automated liquid chromatography-tandem mass spectrometry Proceedings of the National Academy of Sciences of the United States of America. 93: 11115-11120. PMID 8855318 DOI: 10.1073/Pnas.93.20.11115  0.652
1996 Todd S, Semler BL. Structure-infectivity analysis of the human rhinovirus genomic RNA 3' non-coding region Nucleic Acids Research. 24: 2133-2142. PMID 8668546 DOI: 10.1093/Nar/24.11.2133  0.645
1996 Haller AA, Stewart SR, Semler BL. Attenuation stem-loop lesions in the 5′ noncoding region of poliovirus RNA: Neuronal cell-specific translation defects Journal of Virology. 70: 1467-1474. PMID 8627664 DOI: 10.1128/Jvi.70.3.1467-1474.1996  0.64
1996 Blair WS, Nguyen JHC, Parsley TB, Semler BL. Mutations in the poliovirus 3CD proteinase S1-specificity pocket affect substrate recognition and RNA binding Virology. 218: 1-13. PMID 8615011 DOI: 10.1006/Viro.1996.0160  0.546
1995 Haller AA, Semler BL. Stem-Loop Structure Synergy in Binding Cellular Proteins to the 5′| Noncoding Region of Poliovirus RNA Virology. 206: 923-934. PMID 7856105 DOI: 10.1006/Viro.1995.1015  0.645
1995 Blyn LB, Chen R, Semler BL, Ehrenfeld E. Host cell proteins binding to domain IV of the 5′ noncoding region of poliovirus RNA Journal of Virology. 69: 4381-4389. PMID 7769700 DOI: 10.1128/Jvi.69.7.4381-4389.1995  0.65
1995 Todd S, Nguyen JHC, Semler BL. RNA-protein interactions directed by the 3' end of human rhinovirus genomic RNA Journal of Virology. 69: 3605-3614. PMID 7745708 DOI: 10.1128/Jvi.69.6.3605-3614.1995  0.743
1995 Roehl HH, Semler BL. Poliovirus infection enhances the formation of two ribonucleoprotein complexes at the 3' end of viral negative-strand RNA Journal of Virology. 69: 2954-2961. PMID 7707521 DOI: 10.1128/Jvi.69.5.2954-2961.1995  0.703
1995 Ehrenfeld E, Semler BL. Anatomy of the poliovirus internal ribosome entry site Current Topics in Microbiology and Immunology. 203: 65-83. PMID 7555091 DOI: 10.1007/978-3-642-79663-0_3  0.59
1995 Blyn LB, Chen R, Semler BL, Ehrenfeld E. Host cell proteins binding to domain IV of the 5' noncoding region of poliovirus RNA. Journal of Virology. 69: 4381-4389. DOI: 10.1128/jvi.69.7.4381-4389.1995  0.525
1994 Charini WA, Todd S, Gutman GA, Semler BL. Transduction of a human RNA sequence by poliovirus Journal of Virology. 68: 6547-6552. PMID 8083991 DOI: 10.1128/Jvi.68.10.6547-6552.1994  0.666
1993 Blair WS, Li X, Semler BL. A cellular cofactor facilitates efficient 3CD cleavage of the poliovirus P1 precursor Journal of Virology. 67: 2336-2343. PMID 8383245 DOI: 10.1128/Jvi.67.4.2336-2343.1993  0.38
1993 Dougherty WG, Semler BL. Expression of virus-encoded proteinases: functional and structural similarities with cellular enzymes. Microbiological Reviews. 57: 781-822. PMID 8302216 DOI: 10.1128/Mmbr.57.4.781-822.1993  0.429
1993 Haller AA, Nguyen JHC, Semler BL. Minimum internal ribosome entry site required for poliovirus infectivity Journal of Virology. 67: 7461-7471. PMID 8230467 DOI: 10.1128/Jvi.67.12.7461-7471.1993  0.699
1992 Dildine SL, Semler BL. Conservation of RNA-protein interactions among picornaviruses Journal of Virology. 66: 4364-4376. PMID 1602550 DOI: 10.1128/Jvi.66.7.4364-4376.1992  0.653
1992 Lawson MA, Semler BL. Alternate poliovirus nonstructural protein processing cascades generated by primary sites of 3C proteinase cleavage Virology. 191: 309-320. PMID 1329322 DOI: 10.1016/0042-6822(92)90193-S  0.524
1992 Giachetti C, Hwang SS, Semler BL. cis-Acting lesions targeted to the hydrophobic domain of a poliovirus membrane protein involved in RNA replication Journal of Virology. 66: 6045-6057. PMID 1326655 DOI: 10.1128/Jvi.66.10.6045-6057.1992  0.503
1992 Haller AA, Semler BL. Linker scanning mutagenesis of the internal ribosome entry site of poliovirus RNA Journal of Virology. 66: 5075-5086. PMID 1321289 DOI: 10.1128/Jvi.66.8.5075-5086.1992  0.639
1992 De la Torre JC, Giachetti C, Semler BL, Holland JJ. High frequency of single-base transitions and extreme frequency of precise multiple-base reversion mutations in poliovirus Proceedings of the National Academy of Sciences of the United States of America. 89: 2531-2535. PMID 1313561 DOI: 10.1073/Pnas.89.7.2531  0.432
1991 Dildine SL, Stark KR, Haller AA, Semler BL. Poliovirus translation initiation: Differential effects of directed and selected mutations in the 5′ noncoding region of viral RNAs Virology. 182: 742-752. PMID 1850926 DOI: 10.1016/0042-6822(91)90615-I  0.627
1991 Charini WA, Burns CC, Ehrenfeld E, Semler BL. trans Rescue of a Mutant Poliovirus RNA Polymerase Function Journal of Virology. 65: 2655-2665. PMID 1850039 DOI: 10.1128/Jvi.65.5.2655-2665.1991  0.641
1991 Giachetti C, Semler BL. Role of a viral membrane polypeptide in strand-specific initiation of poliovirus RNA synthesis Journal of Virology. 65: 2647-2654. PMID 1850038 DOI: 10.1128/Jvi.65.5.2647-2654.1991  0.704
1991 Blair WS, Semler BL. Self-cleaving proteases Current Opinion in Cell Biology. 3: 1039-1045. PMID 1814362 DOI: 10.1016/0955-0674(91)90126-J  0.357
1990 Lawson MA, Semler BL. Picornavirus protein processing - Enzymes, substrates, and genetic regulation Current Topics in Microbiology and Immunology. 161: 49-87. PMID 2169385  0.353
1990 Lawson MA, Dasmahapatra B, Semler BL. Species-specific substrate interaction of picornavirus 3C proteinase suballelic exchange mutants Journal of Biological Chemistry. 265: 15920-15931. PMID 2168426  0.323
1990 Fu JL, Stein S, Rosenstein L, Bodwell T, Routbort M, Semler BL, Roos RP. Neurovirulence determinants of genetically engineered Theiler viruses. Proceedings of the National Academy of Sciences of the United States of America. 87: 4125-9. PMID 2161533 DOI: 10.1073/Pnas.87.11.4125  0.453
1990 Blair WS, Hwang SS, Ypma-Wong MF, Semler BL. A mutant poliovirus containing a novel proteolytic in VP3 is altered in viral maturation Journal of Virology. 64: 1784-1793. PMID 2157059 DOI: 10.1128/Jvi.64.4.1784-1793.1990  0.39
1990 Dewalt PG, Blair WS, Semler BL. A genetic locus in mutant poliovirus genomes involved in overproduction of RNA polymerase and 3C proteinase Virology. 174: 504-514. PMID 2154885 DOI: 10.1016/0042-6822(90)90104-Y  0.455
1990 Lawson MA, Semler BL. Picornavirus protein processing--enzymes, substrates, and genetic regulation. Current Topics in Microbiology and Immunology. 161: 49-87. DOI: 10.1007/978-3-642-75602-3_3  0.421
1989 Roos RP, Stein S, Ohara Y, Fu J, Semler BL. Infectious cDNA clones of the DA strain of Theiler's murine encephalomyelitis virus Journal of Virology. 63: 5492-5496. PMID 2555569 DOI: 10.1128/Jvi.63.12.5492-5496.1989  0.327
1989 Roos RP, Kong WP, Semler BL. Polyprotein processing of Theiler's murine encephalomyelitis virus Journal of Virology. 63: 5344-5353. PMID 2555559 DOI: 10.1128/Jvi.63.12.5344-5353.1989  0.441
1989 Burns CC, Lawson MA, Semler BL, Ehrenfeld E. Effects of mutations in poliovirus 3D(pol) on RNA polymerase activity and on polyprotein cleavage Journal of Virology. 63: 4866-4874. PMID 2552159 DOI: 10.1128/Jvi.63.11.4866-4874.1989  0.536
1989 Dewalt PG, Lawson MA, Colonno RJ, Semler BL. Chimeric picornavirus polyproteins demonstrate a common 3C proteinase substrate specificity Journal of Virology. 63: 3444-3452. PMID 2545915 DOI: 10.1128/Jvi.63.8.3444-3452.1989  0.387
1989 Dildine SL, Semler BL. The deletion of 41 proximal nucleotides reverts a poliovirus mutant containing a temperature-sensitive lesion in the 5' noncoding region of genomic RNA Journal of Virology. 63: 847-862. PMID 2536107 DOI: 10.1128/Jvi.63.2.847-862.1989  0.65
1988 Kuhn RJ, Tada H, Ypma-Wong MF, Semler BL, Wimmer E. Mutational analysis of the genome-linked protein VPg of poliovirus. Journal of Virology. 62: 4207-15. PMID 2845132 DOI: 10.1128/Jvi.62.11.4207-4215.1988  0.409
1988 Ypma-Wong MF, Dewalt PG, Johnson VH, Lamb JG, Semler BL. Protein 3CD is the major poliovirus proteinase responsible for cleavage of the p1 capsid precursor Virology. 166: 265-270. PMID 2842953 DOI: 10.1016/0042-6822(88)90172-9  0.36
1988 Kuhn RJ, Tada H, Ypma-Wong MF, Dunn JJ, Semler BL, Wimmer E. Construction of a "mutagenesis cartridge" for poliovirus genome-linked viral protein: isolation and characterization of viable and nonviable mutants Proceedings of the National Academy of Sciences of the United States of America. 85: 519-523. PMID 2829191 DOI: 10.1073/Pnas.85.2.519  0.484
1988 Johnson VH, Semler BL. Defined recombinants of poliovirus and coxsackievirus: Sequence-specific deletions and functional substitutions in the 5′-noncoding regions of viral RNAs Virology. 162: 47-57. PMID 2827387 DOI: 10.1016/0042-6822(88)90393-5  0.526
1987 Ypma-Wong MF, Semler BL. Processing determinants required for in vitro cleavage of the poliovirus P1 precursor to capsid proteins Journal of Virology. 61: 3181-3189. PMID 3041039 DOI: 10.1128/Jvi.61.10.3181-3189.1987  0.409
1987 Dewalt PG, Semler BL. Site-directed mutagenesis of proteinase 3C results in a poliovirus deficient in synthesis of viral RNA polymerase Journal of Virology. 61: 2162-2170. PMID 3035216 DOI: 10.1128/Jvi.61.7.2162-2170.1987  0.62
1987 Ypma-Wong MF, Semler BL. In vitro molecular genetics as a tool for determining the differential cleavage specificities of the polivirus 3C proteinase Nucleic Acids Research. 15: 2069-2088. PMID 3031587 DOI: 10.1093/Nar/15.5.2069  0.426
1987 Kuhn RJ, Wimmer E, Semler BL. Expression of the poliovirus genome from infectious cDNA is dependent upon arrangements of eukaryotic and prokaryotic sequences in recombinant plasmids Virology. 157: 560-564. PMID 3029989 DOI: 10.1016/0042-6822(87)90302-3  0.456
1987 Semler BL, Johnson VH, Dewalt PG, Ypma-Wong MF. Site-specific mutagenesis of cDNA clones expressing a poliovirus proteinase Journal of Cellular Biochemistry. 33: 39-51. PMID 3029150 DOI: 10.1002/Jcb.240330105  0.349
1986 Omata T, Kohara M, Kuge S, Komatsu T, Abe S, Semler BL, Kameda A, Itoh H, Arita M, Wimmer E. Genetic analysis of the attenuation phenotype of poliovirus type 1 Journal of Virology. 58: 348-358. PMID 3009852 DOI: 10.1128/Jvi.58.2.348-358.1986  0.393
1986 Kohara M, Abe S, Kuge S, Semler BL, Komatsu T, Arita M, Itoh H, Nomoto A. An Infectious cDNA clone of the poliovirus sabin strain could be used as a stable repository and inoculum for the oral polio live vaccine Virology. 151: 21-30. PMID 3008430 DOI: 10.1016/0042-6822(86)90100-5  0.338
1986 Semler BL, Johnson VH, Tracy S. A chimeric plasmid from cDNA clones of poliovirus and coxsackievirus produces a recombinant virus that is temperature-sensitive Proceedings of the National Academy of Sciences of the United States of America. 83: 1777-1781. PMID 3006071 DOI: 10.1073/Pnas.83.6.1777  0.557
1985 Kohara M, Omata T, Kameda A, Semler BL, Itoh H, Wimmer E, Nomoto A. In vitro phenotypic markers of a poliovirus recombinant constructed from infectious cDNA clones of the neurovirulent Mahoney strain and the attenuated Sabin 1 strain Journal of Virology. 53: 786-792. PMID 2983090 DOI: 10.1128/Jvi.53.3.786-792.1985  0.421
1984 Hanecak R, Semler BL, Ariga H, Anderson CW, Wimmer E. Expression of a cloned gene segment of poliovirus in E. coli: Evidence for autocatalytic production of the viral proteinase Cell. 37: 1063-1073. PMID 6331675 DOI: 10.1016/0092-8674(84)90441-0  0.334
1984 Semler BL, Dorner AJ, Wimmer E. Production of infectious poliovirus from cloned cDNA is dramatically increased by SV40 transcription and replication signals Nucleic Acids Research. 12: 5123-5141. PMID 6330698 DOI: 10.1093/Nar/12.12.5123  0.438
1984 Dorner AJ, Semler BL, Jackson RJ, Hanecak R, Duprey E, Wimmer E. In vitro translation of poliovirus RNA: Utilization of internal initiation sites in reticulocyte lysate Journal of Virology. 50: 507-514. PMID 6323749 DOI: 10.1128/Jvi.50.2.507-514.1984  0.641
1983 Takegami T, Semler BL, Anderson CW, Wimmer E. Membrane fractions active in poliovirus RNA replication contain VPg precursor polypeptides Virology. 128: 33-47. PMID 6308897 DOI: 10.1016/0042-6822(83)90316-1  0.453
1983 Semler BL, Haneck R, Dorner LF, Anderson CW, Wimmer E. Poliovirus RNA synthesis in Vitro: Structuralelements and antibody inhibition Virology. 126: 624-635. PMID 6305005 DOI: 10.1016/S0042-6822(83)80018-X  0.646
1982 Larsen GR, Anderson CW, Dorner AJ, Semler BL, Wimmer E. Cleavage sites within the poliovirus capsid protein precursors Journal of Virology. 41: 340-344. PMID 6283126 DOI: 10.1128/Jvi.41.1.340-344.1982  0.37
1982 Semler BL, Anderson CW, Hanecak R, Dorner LF, Wimmer E. A membrane-associated precursor to poliovirus VPg identified by immunoprecipitation with antibodies directed against a synthetic heptapeptide Cell. 28: 405-412. PMID 6277514 DOI: 10.1016/0092-8674(82)90358-0  0.549
1981 Semler BL, Hanecak R, Anderson CW, Wimmer E. Cleavage sites in the polypeptide precursors of poliovirus protein P2-X Virology. 114: 589-594. PMID 6270891 DOI: 10.1016/0042-6822(81)90242-7  0.327
1981 Semler BL, Anderson CW, Kitamura N, Rothberg PG, Wishart WL, Wimmer E. Poliovirus replication proteins: RNA sequence encoding P3-1b and the sites of proteolytic processing Proceedings of the National Academy of Sciences of the United States of America. 78: 3464-3468. PMID 6267593 DOI: 10.1073/Pnas.78.6.3464  0.424
1981 Kitamura N, Semler BL, Rothberg PG, Larsen GR, Adler CJ, Dorner AJ, Emini EA, Hanecak R, Lee JJ, Van Der Werf S, Anderson CW, Wimmer E. Primary structure, gene organization and polypeptide expression of poliovirus RNA Nature. 291: 547-553. PMID 6264310 DOI: 10.1038/291547A0  0.571
1981 Larsen GR, Semler BL, Wimmer E. Stable hairpin structure within the 5'-terminal 85 nucleotides of poliovirus RNA Journal of Virology. 37: 328-335. PMID 6260985 DOI: 10.1128/Jvi.37.1.328-335.1981  0.639
1980 Golini F, Semler BL, Dorner AJ, Wimmer E. Protein-linked RNA of poliovirus is competent to form an initiation complex of translation in vitro Nature. 287: 600-603. PMID 6253803 DOI: 10.1038/287600A0  0.688
1980 Rowlands D, Grabau E, Spindler K, Jones C, Semler B, Holland J. Virus protein changes and RNA termini alterations evolving during persistent infection Cell. 19: 871-880. PMID 6247073 DOI: 10.1016/0092-8674(80)90078-1  0.471
1979 Perrault J, Semler BL. Internal genome deletions in two distinct classes of defective interfering particles of vesicular stomatitis virus Proceedings of the National Academy of Sciences of the United States of America. 76: 6191-6195. PMID 230501 DOI: 10.1073/Pnas.76.12.6191  0.543
1979 Semler BL, Holland JJ. Persistent vesicular stomatitis virus infection mediates base substitutions in viral RNA termini Journal of Virology. 32: 420-428. PMID 228067 DOI: 10.1128/Jvi.32.2.420-428.1979  0.66
1979 Semler BL, Perrault J, Holland JJ. The nucleotide sequence of the 5′ terminus of vesicular stomatitis virus RNA Nucleic Acids Research. 6: 3923-3934. PMID 226942 DOI: 10.1093/Nar/6.12.3923  0.61
1979 Holland JJ, Grabau EA, Jones CL, Semler BL. Evolution of multiple genome mutations during long-term persistent infection by vesicular stomatitis virus Cell. 16: 495-504. PMID 222463 DOI: 10.1016/0092-8674(79)90024-2  0.427
1978 Semler BL, Perrault J, Abelson J, Holland JJ. Sequence of a RNA templated by the 3'-OH RNA terminus of defective interfering particles of vesicular stomatitis virus Proceedings of the National Academy of Sciences of the United States of America. 75: 4704-4708. PMID 216996 DOI: 10.1073/Pnas.75.10.4704  0.594
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