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Sidney W. Whiteheart - Publications

Affiliations: 
1994- Molecular and Cellular Biochemistry University of Kentucky, Lexington, KY 
Area:
Cell Biology, Biochemistry
Website:
https://biochemistry.med.uky.edu/users/whitehe

140 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Sim MMS, Mollica MY, Alfar HR, Hollifield M, Chung DW, Fu X, Gandhapudi S, Coenen DM, Prakhya KS, Mahmood DFD, Banerjee M, Peng C, Li X, Thornton AC, Porterfield JZ, ... ... Whiteheart SW, et al. Unfolded Von Willebrand Factor Binds Protein S and Reduces Anticoagulant Activity. Biorxiv : the Preprint Server For Biology. PMID 38370737 DOI: 10.1101/2024.02.08.579463  0.312
2023 Alfar HR, Nthenge-Ngumbau DN, Saatman KE, Whiteheart SW. EcoHIV-Infected Mice Show No Signs of Platelet Activation. Viruses. 16. PMID 38257755 DOI: 10.3390/v16010055  0.435
2023 Matharu SS, Nordmann CS, Ottman KR, Akkem R, Palumbo D, Cruz DRD, Campbell K, Sievert G, Sturgill J, Porterfield JZ, Joshi S, Alfar HR, Peng C, Pokrovskaya ID, Kamykowski JA, ... ... Whiteheart SW, et al. Deep learning, 3D ultrastructural analysis reveals quantitative differences in platelet and organelle packing in COVID-19/SARSCoV2 patient-derived platelets. Platelets. 34: 2264978. PMID 37933490 DOI: 10.1080/09537104.2023.2264978  0.468
2023 Smith AN, Joshi S, Chanzu H, Alfar HR, Shravani Prakhya K, Whiteheart SW. α-Synuclein is the major platelet isoform but is dispensable for activation, secretion, and thrombosis. Platelets. 34: 2267147. PMID 37927048 DOI: 10.1080/09537104.2023.2267147  0.502
2023 Joshi S, Prakhya KS, Smith AN, Chanzu H, Zhang M, Whiteheart SW. The complementary roles of VAMP-2, -3, and -7 in platelet secretion and function. Platelets. 34: 2237114. PMID 37545110 DOI: 10.1080/09537104.2023.2237114  0.375
2023 Glendenning LM, Zhou JY, Kukan EN, Gao C, Cummings RD, Joshi S, Whiteheart SW, Cobb BA. Platelet-localized ST6Gal1 does not impact IgG sialylation. Glycobiology. PMID 37379323 DOI: 10.1093/glycob/cwad052  0.409
2023 Prakhya KS, Vekaria H, Coenen DM, Omali L, Lykins J, Joshi S, Alfar HR, Wang QJ, Sullivan P, Whiteheart SW. Platelet glycogenolysis is important for energy production and function. Platelets. 34: 2222184. PMID 37292023 DOI: 10.1080/09537104.2023.2222184  0.468
2022 Prakhya KS, Luo Y, Adkins J, Hu X, Wang QJ, Whiteheart SW. A sensitive and adaptable method to measure platelet-fibrin clot contraction kinetics. Research and Practice in Thrombosis and Haemostasis. 6: e12755. PMID 35873218 DOI: 10.1002/rth2.12755  0.4
2022 Lykins JT, Whiteheart SW. COMManding platelet α-granule cargo. Blood. 139: 809-811. PMID 35142851 DOI: 10.1182/blood.2021015053  0.404
2022 Whiteheart SW. Platelet-HIV: interactions and their implications. Platelets. 33: 208-211. PMID 35086429 DOI: 10.1080/09537104.2021.2019695  0.347
2021 Hubbard WB, Banerjee M, Vekaria H, Prakhya KS, Joshi S, Wang QJ, Saatman KE, Whiteheart SW, Sullivan PG. Differential Leukocyte and Platelet Profiles in Distinct Models of Traumatic Brain Injury. Cells. 10. PMID 33652745 DOI: 10.3390/cells10030500  0.305
2021 Hoover CM, Kondo Y, Shao B, McDaniel M, Lee R, McGee S, Whiteheart SW, Bergmeier W, McEver RP, Xia L. Heightened activation of embryonic megakaryocytes causes aneurysms in the developing brain of mice lacking podoplanin. Blood. PMID 33619517 DOI: 10.1182/blood.2020010310  0.343
2021 Chanzu H, Lykins J, Wigna-Kumar S, Joshi S, Pokrovskaya I, Storrie B, Pejler G, Wood JP, Whiteheart SW. Platelet α-Granule Cargo Packaging and Release are Affected by the Luminal Proteoglycan, Serglycin. Journal of Thrombosis and Haemostasis : Jth. PMID 33448622 DOI: 10.1111/jth.15243  0.387
2021 Huang P, Zhao C, Chen C, Whiteheart SW, Liu-Chen LY. Does GEC1 Enhance Expression and Forward Trafficking of the Kappa Opioid Receptor (KOR) via Its Ability to Interact with NSF Directly? Handbook of Experimental Pharmacology. PMID 33404775 DOI: 10.1007/164_2020_398  0.478
2020 Xiang B, Zhang G, Zhang Y, Wu C, Joshi S, Morris AJ, Ware J, Smyth SS, Whiteheart SW, Li Z. Calcium Ion Chelation Preserves Platelet Function During Cold Storage. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314879. PMID 33176450 DOI: 10.1161/ATVBAHA.120.314879  0.518
2020 Gupta S, Konradt C, Corken A, Ware J, Nieswandt B, Di Paola J, Yu M, Wang D, Nieman MT, Whiteheart SW, Brass LF. Hemostasis vs. homeostasis: Platelets are essential for preserving vascular barrier function in the absence of injury or inflammation. Proceedings of the National Academy of Sciences of the United States of America. PMID 32929010 DOI: 10.1073/Pnas.2007642117  0.525
2020 Pokrovskaya I, Tobin M, Desai R, Aronova MA, Kamykowski JA, Zhang G, Joshi S, Whiteheart SW, Leapman RD, Storrie B. Structural analysis of resting mouse platelets by 3D-EM Reveals an unexpected variation in α-granule shape. Platelets. 1-10. PMID 32815431 DOI: 10.1080/09537104.2020.1799970  0.504
2020 Banerjee M, Huang Y, Joshi S, Popa GJ, Mendenhall MD, Wang QJ, Garvy BA, Myint T, Whiteheart SW. Platelets Endocytose Viral Particles and Are Activated via TLR (Toll-Like Receptor) Signaling. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314180. PMID 32434410 DOI: 10.1161/Atvbaha.120.314180  0.599
2020 Pokrovskaya ID, Tobin M, Desai R, Joshi S, Kamykowski JA, Zhang G, Aronova MA, Whiteheart SW, Leapman RD, Storrie B. Canalicular system reorganization during mouse platelet activation as revealed by 3D ultrastructural analysis. Platelets. 1-8. PMID 32000578 DOI: 10.1080/09537104.2020.1719993  0.591
2020 Smith AN, Joshi S, Whiteheart SW. α‐Synuclein’s Role in Platelet Exocytosis The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06219  0.603
2020 Sim MM, Li X, Bidarian SJ, Song X, Banerjee M, Myint T, Whiteheart SW, Wood JP. A Refined Plasma Thrombin Generation Assay Identifies Functional Importance of the First Two EGF‐like Domains of the Anticoagulant Protein S The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06196  0.376
2019 Banerjee M, Huang Y, Ouseph MM, Joshi S, Pokrovskaya I, Storrie B, Zhang J, Whiteheart SW, Wang QJ. Autophagy in Platelets. Methods in Molecular Biology (Clifton, N.J.). 1880: 511-528. PMID 30610718 DOI: 10.1007/978-1-4939-8873-0_32  0.597
2019 Banerjee M, Sim M, Myint T, Whiteheart SW, Wood JP. Antiretroviral Therapy Does Not Correct the Increased Thrombin Generation and Platelet Hyperactivity Associated with HIV Blood. 134: 3659-3659. DOI: 10.1182/Blood-2019-130070  0.464
2018 Pokrovskaya ID, Joshi S, Tobin M, Desai R, Aronova MA, Kamykowski JA, Zhang G, Whiteheart SW, Leapman RD, Storrie B. SNARE-dependent membrane fusion initiates α-granule matrix decondensation in mouse platelets. Blood Advances. 2: 2947-2958. PMID 30401752 DOI: 10.1182/Bloodadvances.2018019158  0.546
2018 Joshi S, Banerjee M, Zhang J, Kesaraju A, Pokrovskaya ID, Storrie B, Whiteheart SW. Alterations in platelet secretion differentially affect thrombosis and hemostasis. Blood Advances. 2: 2187-2198. PMID 30185436 DOI: 10.1182/Bloodadvances.2018019166  0.623
2018 Zhang J, Huang Y, Chen J, Zhu H, Whiteheart SW. Dynamic cycling of t-SNARE acylation regulates platelet exocytosis. The Journal of Biological Chemistry. 293: 3593-3606. PMID 29352103 DOI: 10.1074/Jbc.Ra117.000140  0.589
2017 Adili R, Voigt EM, Bormann JL, Foss KN, Hurley LJ, Meyer ES, Veldman AJ, Mast KA, West JL, Whiteheart SW, Holinstat M, Larson MK. In vivo modeling of docosahexaenoic acid and eicosapentaenoic acid-mediated inhibition of both platelet function and accumulation in arterial thrombi. Platelets. 1-9. PMID 29286871 DOI: 10.1080/09537104.2017.1420154  0.507
2017 Banerjee M, Joshi S, Zhang J, Moncman CL, Yadav S, Bouchard BA, Storrie B, Whiteheart SW. Cellubrevin/vesicle-associated membrane protein-3-mediated endocytosis and trafficking regulate platelet functions. Blood. 130: 2872-2883. PMID 28931526 DOI: 10.1182/Blood-2017-02-768176  0.659
2017 Whiteheart SW. Fueling Platelets: Where Does the Glucose Come From? Arteriosclerosis, Thrombosis, and Vascular Biology. 37: 1592-1594. PMID 28835484 DOI: 10.1161/Atvbaha.117.309841  0.488
2017 Banerjee M, Whiteheart SW. The ins and outs of endocytic trafficking in platelet functions. Current Opinion in Hematology. 24: 467-474. PMID 28650849 DOI: 10.1097/Moh.0000000000000366  0.59
2017 Storrie B, Whiteheart SW. Editorial: Platelet Secretion. Platelets. 28: 107. PMID 28281920 DOI: 10.1080/09537104.2016.1277676  0.614
2017 Joshi S, Whiteheart SW. The nuts and bolts of the platelet release reaction. Platelets. 28: 129-137. PMID 27848265 DOI: 10.1080/09537104.2016.1240768  0.647
2017 Pokrovskaya ID, Joshi S, Whiteheart SW, Kamykowski J, Storrie B. The Alpha-Granule Release Reaction Is Mediated By SNARE-Dependent Solubilization of the Granule Matrix Blood. 130: 3600-3600. DOI: 10.1182/Blood.V130.Suppl_1.3600.3600  0.326
2016 Eckly A, Rinckel JY, Proamer F, Ulas N, Joshi S, Whiteheart SW, Gachet C. Respective contributions of single and compound granule fusion to secretion by activated platelets. Blood. 128: 2538-2549. PMID 27625359 DOI: 10.1182/Blood-2016-03-705681  0.534
2016 Jones MB, Oswald DM, Joshi S, Whiteheart SW, Orlando R, Cobb BA. B-cell-independent sialylation of IgG. Proceedings of the National Academy of Sciences of the United States of America. 113: 7207-12. PMID 27303031 DOI: 10.1073/Pnas.1523968113  0.391
2016 Banerjee M, Whiteheart SW. How Does Protein Disulfide Isomerase Get Into a Thrombus? Arteriosclerosis, Thrombosis, and Vascular Biology. 36: 1056-7. PMID 27225788 DOI: 10.1161/Atvbaha.116.307625  0.554
2016 Huang Y, Joshi S, Xiang B, Kanaho Y, Li Z, Bouchard BA, Moncman CL, Whiteheart SW. Arf6 controls platelet spreading and clot retraction via integrin αIIbβ3 trafficking. Blood. 127: 1459-67. PMID 26738539 DOI: 10.1182/Blood-2015-05-648550  0.626
2016 Chicka MC, Ren Q, Richards D, Hellman LM, Zhang J, Fried MG, Whiteheart SW. Role of Munc13-4 as a Ca2+-dependent tether during platelet secretion. The Biochemical Journal. 473: 627-39. PMID 26637270 DOI: 10.1042/Bj20151150  0.705
2016 Whiteheart SW. 0190 SNAREs in exocytosis and membrane trafficking Journal of Animal Science. 94: 91-92. DOI: 10.2527/Jam2016-0190  0.316
2015 Xiang B, Zhang G, Ye S, Zhang R, Huang C, Liu J, Tao M, Ruan C, Smyth SS, Whiteheart SW, Li Z. Characterization of a Novel Integrin Binding Protein, VPS33B, Which Is Important for Platelet Activation and In Vivo Thrombosis and Hemostasis. Circulation. 132: 2334-44. PMID 26399659 DOI: 10.1161/Circulationaha.115.018361  0.814
2015 Ouseph MM, Huang Y, Banerjee M, Joshi S, MacDonald L, Zhong Y, Liu H, Li X, Xiang B, Zhang G, Komatsu M, Komatsu M, Yue Z, Li Z, Storrie B, ... Whiteheart SW, et al. Autophagy is induced upon platelet activation and is essential for hemostasis and thrombosis. Blood. 126: 1224-33. PMID 26209658 DOI: 10.1182/Blood-2014-09-598722  0.617
2015 Huang Y, Whiteheart SW. Platelet secretion paves the way. Blood. 126: 433-4. PMID 26206945 DOI: 10.1182/Blood-2015-05-646687  0.535
2014 Ye S, Huang Y, Joshi S, Zhang J, Yang F, Zhang G, Smyth SS, Li Z, Takai Y, Whiteheart SW. Platelet secretion and hemostasis require syntaxin-binding protein STXBP5. The Journal of Clinical Investigation. 124: 4517-28. PMID 25244094 DOI: 10.1172/Jci75572  0.842
2014 Jonnalagadda D, Sunkara M, Morris AJ, Whiteheart SW. Granule-mediated release of sphingosine-1-phosphate by activated platelets. Biochimica Et Biophysica Acta. 1841: 1581-9. PMID 25158625 DOI: 10.1016/J.Bbalip.2014.08.013  0.561
2014 Xiang B, Zhang G, Ye S, Huang C, Liu J, Ruan C, Smyth SS, Whiteheart SW, Li Z. VPS33B, a Member of the Sec1/Munc18 Protein Family, Binds to Integrin Beta Subunits and Is Required for αIIbβ3 Outside-in Signaling Blood. 124: 340-340. DOI: 10.1182/Blood.V124.21.340.340  0.813
2013 Whiteheart SW. α-Granules at the BEACH. Blood. 122: 3247-8. PMID 24203928 DOI: 10.1182/Blood-2013-07-516880  0.403
2013 Xiang B, Zhang G, Guo L, Li XA, Morris AJ, Daugherty A, Whiteheart SW, Smyth SS, Li Z. Platelets protect from septic shock by inhibiting macrophage-dependent inflammation via the cyclooxygenase 1 signalling pathway. Nature Communications. 4: 2657. PMID 24150174 DOI: 10.1038/Ncomms3657  0.536
2013 Karim ZA, Zhang J, Banerjee M, Chicka MC, Al Hawas R, Hamilton TR, Roche PA, Whiteheart SW. IκB kinase phosphorylation of SNAP-23 controls platelet secretion. Blood. 121: 4567-74. PMID 23613522 DOI: 10.1182/Blood-2012-11-470468  0.833
2012 Jonnalagadda D, Izu LT, Whiteheart SW. Platelet secretion is kinetically heterogeneous in an agonist-responsive manner. Blood. 120: 5209-16. PMID 23086755 DOI: 10.1182/Blood-2012-07-445080  0.527
2012 Xiang B, Zhang G, Stefanini L, Bergmeier W, Gartner TK, Whiteheart SW, Li Z. The Src family kinases and protein kinase C synergize to mediate Gq-dependent platelet activation. The Journal of Biological Chemistry. 287: 41277-87. PMID 23066026 DOI: 10.1074/Jbc.M112.393124  0.558
2012 Al Hawas R, Ren Q, Ye S, Karim ZA, Filipovich AH, Whiteheart SW. Munc18b/STXBP2 is required for platelet secretion. Blood. 120: 2493-500. PMID 22791290 DOI: 10.1182/Blood-2012-05-430629  0.843
2012 Ye S, Karim ZA, Al Hawas R, Pessin JE, Filipovich AH, Whiteheart SW. Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion. Blood. 120: 2484-92. PMID 22767500 DOI: 10.1182/Blood-2012-05-430603  0.849
2012 Moeller A, Zhao C, Fried MG, Wilson-Kubalek EM, Carragher B, Whiteheart SW. Nucleotide-dependent conformational changes in the N-Ethylmaleimide Sensitive Factor (NSF) and their potential role in SNARE complex disassembly. Journal of Structural Biology. 177: 335-43. PMID 22245547 DOI: 10.1016/J.Jsb.2011.12.018  0.523
2012 Matveeva EA, Price DA, Whiteheart SW, Vanaman TC, Gerhardt GA, Slevin JT. Reduction of vesicle-associated membrane protein 2 expression leads to a kindling-resistant phenotype in a murine model of epilepsy. Neuroscience. 202: 77-86. PMID 22183055 DOI: 10.1016/J.Neuroscience.2011.11.055  0.368
2012 Zhao C, Smith EC, Whiteheart SW. Requirements for the catalytic cycle of the N-ethylmaleimide-Sensitive Factor (NSF). Biochimica Et Biophysica Acta. 1823: 159-71. PMID 21689688 DOI: 10.1016/J.Bbamcr.2011.06.003  0.542
2012 Whiteheart SW. Temporal Secretion of α-Granular Products: Insights into the Mechanisms of Release Reaction Blood. 120: SCI-36-SCI-36. DOI: 10.1182/Blood.V120.21.Sci-36.Sci-36  0.661
2012 Xiang B, Zhang G, Li X, Morris AJ, Daugherty A, Whiteheart SW, Smyth SS, Li Z. Platelets Protect From Lipopolysaccharide-Induced Lethal Endotoxemia by Inhibiting Macrophage-Dependent Inflammation Via the Cyclooxygenase 1 (COX1) Signaling Pathway Blood. 120: 93-93. DOI: 10.1182/Blood.V120.21.93.93  0.528
2012 Elverson HE, Hellman LM, Melikishvili M, Zhao C, Whiteheart SW, Fried MG. Histidine-Tag-Specific Optical Probes for Analytical Ultracentrifugation Analysis Biophysical Journal. 102: 483a-484a. DOI: 10.1016/J.Bpj.2011.11.2650  0.534
2011 Zhang G, Xiang B, Ye S, Chrzanowska-Wodnicka M, Morris AJ, Gartner TK, Whiteheart SW, White GC, Smyth SS, Li Z. Distinct roles for Rap1b protein in platelet secretion and integrin αIIbβ3 outside-in signaling. The Journal of Biological Chemistry. 286: 39466-77. PMID 21940635 DOI: 10.1074/Jbc.M111.239608  0.824
2011 Whiteheart SW. Platelet granules: surprise packages. Blood. 118: 1190-1. PMID 21816838 DOI: 10.1182/Blood-2011-06-359836  0.548
2011 Feng W, Madajka M, Kerr BA, Mahabeleshwar GH, Whiteheart SW, Byzova TV. A novel role for platelet secretion in angiogenesis: mediating bone marrow-derived cell mobilization and homing. Blood. 117: 3893-902. PMID 21224474 DOI: 10.1182/Blood-2010-08-304808  0.521
2011 Hellman LM, Zhao C, Melikishvili M, Tao X, Hopper JE, Whiteheart SW, Fried MG. Histidine-tag-directed chromophores for tracer analyses in the analytical ultracentrifuge. Methods (San Diego, Calif.). 54: 31-8. PMID 21187151 DOI: 10.1016/J.Ymeth.2010.12.033  0.486
2011 Zhang G, Xiang B, Shaojing Y, Chrzanowska-Wodnicka M, Morris AJ, Gartner TK, Whiteheart SW, White GC, Smyth SS, Li Z. DISTINCT ROLES for Rap1b In PLATELET SECRETION and INTEGRIN aIIBb3 OUTSIDE-In SIGNALING Blood. 118: 2200-2200. DOI: 10.1182/Blood.V118.21.2200.2200  0.628
2011 Feng W, Madajka M, Kerr BA, Mahabeleshwar GH, Whiteheart SW, Byzova TV. A novel role for platelet secretion in angiogenesis: Mediating bone marrow-derived cell mobilization and homing (Blood (2011) 117, 14, (3893-3902)) Blood. 117: 7187. DOI: 10.1182/Blood-2011-04-348094  0.434
2010 Ren Q, Wimmer C, Chicka MC, Ye S, Ren Y, Hughson FM, Whiteheart SW. Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis. Blood. 116: 869-77. PMID 20435885 DOI: 10.1182/Blood-2010-02-270934  0.88
2010 Choi W, Karim ZA, Whiteheart SW. Protein expression in platelets from six species that differ in their open canalicular system. Platelets. 21: 167-75. PMID 20196629 DOI: 10.3109/09537101003611385  0.854
2010 Zhao C, Hellman LM, Zhan X, Bowman WS, Whiteheart SW, Fried MG. Hexahistidine-tag-specific optical probes for analyses of proteins and their interactions. Analytical Biochemistry. 399: 237-45. PMID 20036207 DOI: 10.1016/J.Ab.2009.12.028  0.532
2010 Kondkar AA, Bray MS, Leal SM, Nagalla S, Liu DJ, Jin Y, Dong JF, Ren Q, Whiteheart SW, Shaw C, Bray PF. VAMP8/endobrevin is overexpressed in hyperreactive human platelets: suggested role for platelet microRNA. Journal of Thrombosis and Haemostasis : Jth. 8: 369-78. PMID 19943878 DOI: 10.1111/J.1538-7836.2009.03700.X  0.733
2010 Zhao C, Matveeva EA, Ren Q, Whiteheart SW. Dissecting the N-ethylmaleimide-sensitive factor: required elements of the N and D1 domains. The Journal of Biological Chemistry. 285: 761-72. PMID 19887446 DOI: 10.1074/Jbc.M109.056739  0.667
2010 Min SH, Suzuki A, Zhao L, Lian L, Whiteheart SW, Marks MS, Choi JK, Abrams CS. Loss of PIKFyve In Murine Platelets Leads to Aberrant Platelet Granule Biogenesis and a Pleomorphic Phenotype with Multiorgan Failure Blood. 116: 159-159. DOI: 10.1182/Blood.V116.21.159.159  0.549
2010 Zhao C, Hellman LM, Zhan X, Whiteheart SW, Fried MG. (his)6-Tag-Specific Optical Probes For Analyses of Proteins and Their Interactions Biophysical Journal. 98: 60a. DOI: 10.1016/J.Bpj.2009.12.345  0.53
2009 Graham GJ, Ren Q, Dilks JR, Blair P, Whiteheart SW, Flaumenhaft R. Endobrevin/VAMP-8-dependent dense granule release mediates thrombus formation in vivo. Blood. 114: 1083-90. PMID 19395672 DOI: 10.1182/Blood-2009-03-210211  0.761
2009 Konopatskaya O, Gilio K, Harper MT, Zhao Y, Cosemans JM, Karim ZA, Whiteheart SW, Molkentin JD, Verkade P, Watson SP, Heemskerk JW, Poole AW. PKCalpha regulates platelet granule secretion and thrombus formation in mice. The Journal of Clinical Investigation. 119: 399-407. PMID 19147982 DOI: 10.1172/Jci34665  0.602
2008 Ren Q, Ye S, Whiteheart SW. The platelet release reaction: just when you thought platelet secretion was simple. Current Opinion in Hematology. 15: 537-41. PMID 18695380 DOI: 10.1097/Moh.0B013E328309Ec74  0.855
2008 Matveeva EA, Vanaman TC, Whiteheart SW, Slevin JT. Levetiracetam prevents kindling-induced asymmetric accumulation of hippocampal 7S SNARE complexes. Epilepsia. 49: 1749-58. PMID 18513349 DOI: 10.1111/J.1528-1167.2008.01687.X  0.404
2008 Crawford GL, Hart GW, Whiteheart SW. Murine platelets are not regulated by O-linked beta-N-acetylglucosamine. Archives of Biochemistry and Biophysics. 474: 220-4. PMID 18387355 DOI: 10.1016/J.Abb.2008.03.014  0.828
2008 Karim ZA, Choi W, Whiteheart SW. Primary platelet signaling cascades and integrin-mediated signaling control ADP-ribosylation factor (Arf) 6-GTP levels during platelet activation and aggregation. The Journal of Biological Chemistry. 283: 11995-2003. PMID 18326492 DOI: 10.1074/Jbc.M800146200  0.839
2008 Smyth SS, Monroe DM, Wysokinski WE, McBane RD, Whiteheart SW, Becker RC, Steinhubl SR. Platelet activation and its patient-specific consequences. Thrombosis Research. 122: 435-41. PMID 17949794 DOI: 10.1016/J.Thromres.2007.08.023  0.533
2008 Blair PS, Ren Q, Graham GJ, Dilks JR, Whiteheart SW, Flaumenhaft RC. Endobrevin/VAMP-8-Mediated Dense Granule Release Is Required for Efficient Thrombus Formation in Vivo. Blood. 112: 1836-1836. DOI: 10.1182/blood.v112.11.1836.1836  0.668
2007 Badol P, David-Dufilho M, Auger J, Whiteheart SW, Rendu F. Thiosulfinates modulate platelet activation by reaction with surface free sulfhydryls and internal thiol-containing proteins. Platelets. 18: 481-90. PMID 17852771 DOI: 10.1080/09537100701271828  0.576
2007 Zhao C, Slevin JT, Whiteheart SW. Cellular functions of NSF: not just SNAPs and SNAREs. Febs Letters. 581: 2140-9. PMID 17397838 DOI: 10.1016/J.Febslet.2007.03.032  0.58
2007 Matveeva EA, Vanaman TC, Whiteheart SW, Slevin JT. Asymmetric accumulation of hippocampal 7S SNARE complexes occurs regardless of kindling paradigm. Epilepsy Research. 73: 266-74. PMID 17174072 DOI: 10.1016/J.Eplepsyres.2006.11.003  0.301
2007 Ren Q, Barber HK, Crawford GL, Karim ZA, Zhao C, Choi W, Wang CC, Hong W, Whiteheart SW. Endobrevin/VAMP-8 is the primary v-SNARE for the platelet release reaction. Molecular Biology of the Cell. 18: 24-33. PMID 17065550 DOI: 10.1091/Mbc.E06-09-0785  0.855
2007 Ye S, Ren Q, Whiteheart SW. The role of Sec1/Munc18 proteins in platelet secretion The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A245-E  0.856
2006 Choi W, Karim ZA, Whiteheart SW. Arf6 plays an early role in platelet activation by collagen and convulxin. Blood. 107: 3145-52. PMID 16352809 DOI: 10.1182/Blood-2005-09-3563  0.84
2005 Schraw T, Whiteheart S. The development of a quantitative enzyme-linked immunosorbent assay to detect human platelet factor 4. Transfusion. 45: 717-24. PMID 15847660 DOI: 10.1111/J.1537-2995.2005.04243.X  0.827
2005 Hepp R, Puri N, Hohenstein AC, Crawford GL, Whiteheart SW, Roche PA. Phosphorylation of SNAP-23 regulates exocytosis from mast cells. The Journal of Biological Chemistry. 280: 6610-20. PMID 15611044 DOI: 10.1074/Jbc.M412126200  0.796
2005 Gage RM, Matveeva EA, Whiteheart SW, von Zastrow M. Type I PDZ ligands are sufficient to promote rapid recycling of G Protein-coupled receptors independent of binding to N-ethylmaleimide-sensitive factor. The Journal of Biological Chemistry. 280: 3305-13. PMID 15548537 DOI: 10.1074/Jbc.M406934200  0.347
2004 Schraw TD, Crawford GL, Ren Q, Choi W, Thurmond DC, Pessin J, Whiteheart SW. Platelets from Munc18c heterozygous mice exhibit normal stimulus-induced release. Thrombosis and Haemostasis. 92: 829-37. PMID 15467915 DOI: 10.1160/Th04-04-0263  0.836
2004 Rutledge TW, Whiteheart SW. Studies of secretion using permeabilized platelets. Methods in Molecular Biology (Clifton, N.J.). 272: 109-20. PMID 15226539 DOI: 10.1385/1-59259-782-3:109  0.864
2004 Ogura T, Whiteheart SW, Wilkinson AJ. Conserved arginine residues implicated in ATP hydrolysis, nucleotide-sensing, and inter-subunit interactions in AAA and AAA+ ATPases. Journal of Structural Biology. 146: 106-12. PMID 15095758 DOI: 10.1016/J.Jsb.2003.11.008  0.304
2004 Whiteheart SW, Matveeva EA. Multiple binding proteins suggest diverse functions for the N-ethylmaleimide sensitive factor. Journal of Structural Biology. 146: 32-43. PMID 15037235 DOI: 10.1016/J.Jsb.2003.09.015  0.378
2004 Dean WL, Whiteheart SW. Plasma membrane Ca(2+)-ATPase (PMCA) translocates to filopodia during platelet activation. Thrombosis and Haemostasis. 91: 325-33. PMID 14961161 DOI: 10.1160/Th03-07-0425  0.538
2004 Whiteheart SW, Kubalek EW. SNAPs and NSF: general members of the fusion apparatus. Trends in Cell Biology. 5: 64-8. PMID 14731414 DOI: 10.1016/S0962-8924(00)88948-5  0.375
2003 Puri N, Kruhlak MJ, Whiteheart SW, Roche PA. Mast cell degranulation requires N-ethylmaleimide-sensitive factor-mediated SNARE disassembly. Journal of Immunology (Baltimore, Md. : 1950). 171: 5345-52. PMID 14607937 DOI: 10.4049/Jimmunol.171.10.5345  0.424
2003 Schraw TD, Lemons PP, Dean WL, Whiteheart SW. A role for Sec1/Munc18 proteins in platelet exocytosis. The Biochemical Journal. 374: 207-17. PMID 12773094 DOI: 10.1042/Bj20030610  0.86
2003 Schraw TD, Rutledge TW, Crawford GL, Bernstein AM, Kalen AL, Pessin JE, Whiteheart SW. Granule stores from cellubrevin/VAMP-3 null mouse platelets exhibit normal stimulus-induced release. Blood. 102: 1716-22. PMID 12738662 DOI: 10.1182/Blood-2003-01-0331  0.836
2003 Matveeva EA, Whiteheart SW, Slevin JT. Accumulation of 7S SNARE complexes in hippocampal synaptosomes from chronically kindled rats. Journal of Neurochemistry. 84: 621-4. PMID 12558983 DOI: 10.1046/J.1471-4159.2003.01589.X  0.307
2003 Skrzypek E, Myers-Morales T, Whiteheart SW, Straley SC. Application of a Saccharomyces cerevisiae model to study requirements for trafficking of Yersinia pestis YopM in eucaryotic cells. Infection and Immunity. 71: 937-47. PMID 12540576 DOI: 10.1128/Iai.71.2.937-947.2003  0.302
2002 Rutledge TW, Whiteheart SW. SNAP-23 is a target for calpain cleavage in activated platelets. The Journal of Biological Chemistry. 277: 37009-15. PMID 12121992 DOI: 10.1074/Jbc.M204526200  0.861
2002 Matveeva EA, May AP, He P, Whiteheart SW. Uncoupling the ATPase activity of the N-ethylmaleimide sensitive factor (NSF) from 20S complex disassembly. Biochemistry. 41: 530-6. PMID 11781091 DOI: 10.1021/Bi015632S  0.329
2001 Whiteheart SW, Schraw T, Matveeva EA. N-ethylmaleimide sensitive factor (NSF) structure and function. International Review of Cytology. 207: 71-112. PMID 11352269 DOI: 10.1016/S0074-7696(01)07003-6  0.786
2001 Chen D, Xu W, He P, Medrano EE, Whiteheart SW. Gaf-1, a gamma -SNAP-binding protein associated with the mitochondria. The Journal of Biological Chemistry. 276: 13127-35. PMID 11278501 DOI: 10.1074/Jbc.M009424200  0.324
2001 Matveeva EA, Whiteheart SW, Vanaman TC, Slevin JT. Phosphorylation of the N-Ethylmaleimide-sensitive Factor Is Associated with Depolarization-dependent Neurotransmitter Release from Synaptosomes Journal of Biological Chemistry. 276: 12174-12181. PMID 11278345 DOI: 10.1074/Jbc.M007394200  0.361
2000 Southard RC, Haggard J, Crider ME, Whiteheart SW, Cooper RL. Influence of serotonin on the kinetics of vesicular release. Brain Research. 871: 16-28. PMID 10882778 DOI: 10.1016/S0006-8993(00)02347-7  0.341
2000 Lemons PP, Chen D, Whiteheart SW. Molecular mechanisms of platelet exocytosis: requirements for alpha-granule release. Biochemical and Biophysical Research Communications. 267: 875-80. PMID 10673384 DOI: 10.1006/Bbrc.1999.2039  0.595
2000 Chen D, Lemons PP, Schraw T, Whiteheart SW. Molecular mechanisms of platelet exocytosis: role of SNAP-23 and syntaxin 2 and 4 in lysosome release Blood. 96: 1782-1788. DOI: 10.1182/Blood.V96.5.1782  0.828
2000 Chen D, Bernstein AM, Lemons PP, Whiteheart SW. Molecular mechanisms of platelet exocytosis: role of SNAP-23 and syntaxin 2 in dense core granule release Blood. 95: 921-929. DOI: 10.1182/Blood.V95.3.921.003K17_921_929  0.549
1999 He P, Southard RC, Chen D, Whiteheart SW, Cooper RL. Role of alpha-SNAP in promoting efficient neurotransmission at the crayfish neuromuscular junction. Journal of Neurophysiology. 82: 3406-16. PMID 10601471 DOI: 10.1152/Jn.1999.82.6.3406  0.318
1999 May AP, Misura KM, Whiteheart SW, Weis WI. Crystal structure of the amino-terminal domain of N-ethylmaleimide-sensitive fusion protein. Nature Cell Biology. 1: 175-82. PMID 10559905 DOI: 10.1038/11097  0.332
1999 Richards-Smith B, Novak EK, Jang EK, He P, Haslam RJ, Castle D, Whiteheart SW, Swank RT. Analyses of proteins involved in vesicular trafficking in platelets of mouse models of Hermansky Pudlak syndrome. Molecular Genetics and Metabolism. 68: 14-23. PMID 10479478 DOI: 10.1006/Mgme.1999.2891  0.519
1999 Chen D, Minger SL, Honer WG, Whiteheart SW. Organization of the secretory machinery in the rodent brain: distribution of the t-SNAREs, SNAP-25 and SNAP-23. Brain Research. 831: 11-24. PMID 10411979 DOI: 10.1016/S0006-8993(99)01371-2  0.337
1999 Chen D, Whiteheart SW. Intracellular localization of SNAP-23 to endosomal compartments. Biochemical and Biophysical Research Communications. 255: 340-6. PMID 10049710 DOI: 10.1006/Bbrc.1999.0173  0.362
1999 Bernstein AM, Whiteheart SW. Identification of a Cellubrevin/Vesicle Associated Membrane Protein 3 Homologue in Human Platelets Blood. 93: 571-579. DOI: 10.1182/Blood.V93.2.571  0.571
1998 Matveeva E, Whiteheart SW. The effects of SNAP/SNARE complexes on the ATPase of NSF. Febs Letters. 435: 211-4. PMID 9762911 DOI: 10.1016/S0014-5793(98)01071-0  0.332
1998 Lenzen CU, Steinmann D, Whiteheart SW, Weis WI. Crystal structure of the hexamerization domain of N-ethylmaleimide-sensitive fusion protein. Cell. 94: 525-36. PMID 9727495 DOI: 10.1016/S0092-8674(00)81593-7  0.302
1998 Leung SM, Chen D, DasGupta BR, Whiteheart SW, Apodaca G. SNAP-23 requirement for transferrin recycling in Streptolysin-O-permeabilized Madin-Darby canine kidney cells. The Journal of Biological Chemistry. 273: 17732-41. PMID 9651373 DOI: 10.1074/Jbc.273.28.17732  0.363
1998 Low SH, Chapin SJ, Wimmer C, Whiteheart SW, Kömüves LG, Mostov KE, Weimbs T. The SNARE machinery is involved in apical plasma membrane trafficking in MDCK cells. The Journal of Cell Biology. 141: 1503-13. PMID 9647644 DOI: 10.1083/Jcb.141.7.1503  0.376
1998 Colombo MI, Gelberman SC, Whiteheart SW, Stahl PD. N-ethylmaleimide-sensitive factor-dependent α-SNAP release, an early event in the docking/fusion process, is not regulated by Rab GTPases Journal of Biological Chemistry. 273: 1334-1338. PMID 9430666 DOI: 10.1074/Jbc.273.3.1334  0.318
1997 Matveeva EA, He P, Whiteheart SW. N-Ethylmaleimide-sensitive fusion protein contains high and low affinity ATP-binding sites that are functionally distinct. The Journal of Biological Chemistry. 272: 26413-8. PMID 9334216 DOI: 10.1074/Jbc.272.42.26413  0.319
1997 Lemons PP, Chen D, Bernstein AM, Bennett MK, Whiteheart S. Regulated Secretion in Platelets: Identification of Elements of the Platelet Exocytosis Machinery Blood. 90: 1490-1500. DOI: 10.1182/Blood.V90.4.1490.1490_1490_1500  0.632
1996 Timmers KI, Clark AE, Omatsu-Kanbe M, Whiteheart SW, Bennett MK, Holman GD, Cushman SW. Identification of SNAP receptors in rat adipose cell membrane fractions and in SNARE complexes co-immunoprecipitated with epitope-tagged N-ethylmaleimide-sensitive fusion protein. The Biochemical Journal. 320: 429-36. PMID 8973549 DOI: 10.1042/Bj3200429  0.357
1996 Colombo MI, Taddese M, Whiteheart SW, Stahl PD. A possible predocking attachment site for N-ethylmaleimide-sensitive fusion protein. Insights from in vitro endosome fusion Journal of Biological Chemistry. 271: 18810-18816. PMID 8702539 DOI: 10.1074/Jbc.271.31.18810  0.375
1996 Apodaca G, Cardone MH, Whiteheart SW, DasGupta BR, Mostov KE. Reconstitution of transcytosis in SLO-permeabilized MDCK cells: existence of an NSF-dependent fusion mechanism with the apical surface of MDCK cells. The Embo Journal. 15: 1471-81. PMID 8612570 DOI: 10.1002/J.1460-2075.1996.Tb00491.X  0.387
1996 Nagiec EE, Bernstein A, Whiteheart SW. Each domain of the N-ethylmaleimide-sensitive fusion protein contributes to its transport activity. The Journal of Biological Chemistry. 270: 29182-8. PMID 7493945 DOI: 10.1074/Jbc.270.49.29182  0.327
1995 DeBello WM, O'Connor V, Dresbach T, Whiteheart SW, Wang SS, Schweizer FE, Betz H, Rothman JE, Augustine GJ. SNAP-mediated protein-protein interactions essential for neurotransmitter release. Nature. 373: 626-30. PMID 7854421 DOI: 10.1038/373626A0  0.584
1994 Whiteheart SW, Hart GW. Incorporation of [3H]ethanolamine into a single cytosolic protein in a cell free system: ethanolaminylation of EF-1 alpha in vitro. Archives of Biochemistry and Biophysics. 309: 387-91. PMID 8135552 DOI: 10.1006/Abbi.1994.1128  0.559
1994 Whiteheart SW, Rossnagel K, Buhrow SA, Brunner M, Jaenicke R, Rothman JE. N-ethylmaleimide-sensitive fusion protein: a trimeric ATPase whose hydrolysis of ATP is required for membrane fusion. The Journal of Cell Biology. 126: 945-54. PMID 8051214 DOI: 10.1083/Jcb.126.4.945  0.67
1993 Whiteheart SW, Griff IC, Brunner M, Clary DO, Mayer T, Buhrow SA, Rothman JE. SNAP family of NSF attachment proteins includes a brain-specific isoform. Nature. 362: 353-5. PMID 8455721 DOI: 10.1038/362353A0  0.677
1993 Söllner T, Whiteheart SW, Brunner M, Erdjument-Bromage H, Geromanos S, Tempst P, Rothman JE. SNAP receptors implicated in vesicle targeting and fusion Nature. 362: 318-324. PMID 8455717 DOI: 10.1038/362318A0  0.692
1993 Söllner T, Bennett MK, Whiteheart SW, Scheller RH, Rothman JE. A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion. Cell. 75: 409-18. PMID 8221884 DOI: 10.1016/0092-8674(93)90376-2  0.582
1992 Whiteheart SW, Brunner M, Wilson DW, Wiedmann M, Rothman JE. Soluble N-ethylmaleimide-sensitive fusion attachment proteins (SNAPs) bind to a multi-SNAP receptor complex in Golgi membranes Journal of Biological Chemistry. 267: 12239-12243. PMID 1601890  0.521
1992 Wilson DW, Whiteheart SW, Wiedmann M, Brunner M, Rothman JE. A multisubunit particle implicated in membrane fusion Journal of Cell Biology. 117: 531-538. PMID 1315316 DOI: 10.1083/Jcb.117.3.531  0.685
1991 Wilson DW, Whiteheart SW, Orci L, Rothman JE. Intracellular membrane fusion. Trends in Biochemical Sciences. 16: 334-7. PMID 1949154 DOI: 10.1016/0968-0004(91)90138-L  0.547
1990 Whiteheart SW, McLenithan JC, Hart GW. Surfaces of murine lymphocyte subsets differ in sialylation states and antigen distribution of a major N-linked penultimate saccharide structure. Cellular Immunology. 125: 337-53. PMID 2137033 DOI: 10.1016/0008-8749(90)90089-A  0.5
1989 Whiteheart SW, Shenbagamurthi P, Chen L, Cotter RJ, Hart GW. Murine elongation factor 1 alpha (EF-1 alpha) is posttranslationally modified by novel amide-linked ethanolamine-phosphoglycerol moieties. Addition of ethanolamine-phosphoglycerol to specific glutamic acid residues on EF-1 alpha. The Journal of Biological Chemistry. 264: 14334-41. PMID 2569467  0.44
1989 Whiteheart SW, Passaniti A, Reichner JS, Holt GD, Haltiwanger RS, Hart GW. Glycosyltransferase probes Methods in Enzymology. 179: 82-95. PMID 2516227 DOI: 10.1016/0076-6879(89)79116-3  0.657
1988 Reichner JS, Whiteheart SW, Hart GW. Intracellular trafficking of cell surface sialoglycoconjugates. The Journal of Biological Chemistry. 263: 16316-26. PMID 3182795  0.456
1987 Whiteheart SW, Hart GW. Sialyltransferases as specific cell surface probes of terminal and penultimate saccharide structures on living cells. Analytical Biochemistry. 163: 123-35. PMID 3304006 DOI: 10.1016/0003-2697(87)90102-3  0.498
1987 Powell LD, Whiteheart SW, Hart GW. Cell surface sialic acid influences tumor cell recognition in the mixed lymphocyte reaction. Journal of Immunology (Baltimore, Md. : 1950). 139: 262-70. PMID 2953814  0.472
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