Jerome A. Zack - Publications

Affiliations: 
Microbiology, Immunology, & Molecular Genetics 0440 University of California, Los Angeles, Los Angeles, CA 
Area:
Immunology, Human Development, Virology Biology

186 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kim JT, Bresson-Tan G, Zack JA. Current Advances in Humanized Mouse Models for Studying NK Cells and HIV Infection. Microorganisms. 11. PMID 37630544 DOI: 10.3390/microorganisms11081984  0.419
2023 Moran JA, Ranjan A, Hourani R, Kim JT, Wender PA, Zack JA, Marsden MD. Secreted factors induced by PKC modulators do not indirectly cause HIV latency reversal. Virology. 581: 8-14. PMID 36842270 DOI: 10.1016/j.virol.2023.02.009  0.516
2022 Kim JT, Zack JA. A humanized mouse model to study NK cell biology during HIV infection. The Journal of Clinical Investigation. 132. PMID 36519544 DOI: 10.1172/JCI165620  0.461
2022 Kim JT, Zhang TH, Carmona C, Lee B, Seet CS, Kostelny M, Shah N, Chen H, Farrell K, Soliman MSA, Dimapasoc M, Sinani M, Blanco KYR, Bojorquez D, Jiang H, ... ... Zack JA, et al. Latency reversal plus natural killer cells diminish HIV reservoir in vivo. Nature Communications. 13: 121. PMID 35013215 DOI: 10.1038/s41467-021-27647-0  0.538
2021 Zhen A, Carrillo MA, Mu W, Rezek V, Martin H, Hamid P, Chen ISY, Yang OO, Zack JA, Kitchen SG. Robust CAR-T memory formation and function via hematopoietic stem cell delivery. Plos Pathogens. 17: e1009404. PMID 33793675 DOI: 10.1371/journal.ppat.1009404  0.578
2021 Barber-Axthelm IM, Barber-Axthelm V, Sze KY, Zhen A, Suryawanshi GW, Chen IS, Zack JA, Kitchen SG, Kiem HP, Peterson CW. Stem cell-derived CAR T cells traffic to HIV reservoirs in macaques. Jci Insight. 6. PMID 33427210 DOI: 10.1172/jci.insight.141502  0.534
2020 Marsden MD, Zhang TH, Du Y, Dimapasoc M, Soliman MSA, Wu X, Kim JT, Shimizu A, Schrier A, Wender PA, Sun R, Zack JA. Tracking HIV Rebound following Latency Reversal Using Barcoded HIV. Cell Reports. Medicine. 1: 100162. PMID 33377133 DOI: 10.1016/j.xcrm.2020.100162  0.539
2020 Pache L, Marsden MD, Teriete P, Portillo AJ, Heimann D, Kim JT, Soliman MSA, Dimapasoc M, Carmona C, Celeridad M, Spivak AM, Planelles V, Cosford NDP, Zack JA, Chanda SK. Pharmacological Activation of Non-canonical NF-κB Signaling Activates Latent HIV-1 Reservoirs . Cell Reports. Medicine. 1: 100037. PMID 33205060 DOI: 10.1016/j.xcrm.2020.100037  0.484
2020 Sloane JL, Benner NL, Keenan KN, Zang X, Soliman MSA, Wu X, Dimapasoc M, Chun TW, Marsden MD, Zack JA, Wender PA. Prodrugs of PKC modulators show enhanced HIV latency reversal and an expanded therapeutic window. Proceedings of the National Academy of Sciences of the United States of America. PMID 32371485 DOI: 10.1073/Pnas.1919408117  0.462
2020 Hardman C, Ho S, Shimizu A, Luu-Nguyen Q, Sloane JL, Soliman MSA, Marsden MD, Zack JA, Wender PA. Synthesis and evaluation of designed PKC modulators for enhanced cancer immunotherapy. Nature Communications. 11: 1879. PMID 32312992 DOI: 10.1038/S41467-020-15742-7  0.416
2019 Zhu Y, Smith DJ, Zhou Y, Li YR, Yu J, Lee D, Wang YC, Di Biase S, Wang X, Hardoy C, Ku J, Tsao T, Lin LJ, Pham AT, Moon H, ... ... Zack JA, et al. Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. Cell Stem Cell. PMID 31495780 DOI: 10.1016/J.Stem.2019.08.004  0.436
2019 Galli V, Nixon CC, Strbo N, Artesi M, de Castro-Amarante MF, McKinnon K, Fujikawa D, Omsland M, Washington-Parks R, Romero L, Caruso B, Durkin K, Brown S, Karim B, Vaccari M, ... ... Zack JA, et al. Essential Role of HTLV-1 in Lethal Proliferation of CD4 Cells in Humanized Mice. Journal of Virology. PMID 31315992 DOI: 10.1128/Jvi.00565-19  0.523
2019 Llewellyn GN, Seclèn E, Wietgrefe S, Liu S, Chateau M, Pei H, Perkey K, Marsden MD, Hinkley SJ, Paschon DE, Holmes MC, Zack JA, Louie SG, Haase AT, Cannon PM. A humanized mouse model of HIV-1 latency with enrichment of latent virus in PD-1+ and TIGIT+ CD4 T cells. Journal of Virology. PMID 30842333 DOI: 10.1128/Jvi.02086-18  0.64
2019 Hazim RA, Karumbayaram S, Jiang M, Dimashkie A, Lopes VS, Li D, Burgess BL, Vijayaraj P, Alva-Ornelas JA, Zack JA, Kohn DB, Gomperts BN, Pyle AD, Lowry WE, Williams DS. Correction to: Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization. Stem Cell Research & Therapy. 10: 52. PMID 30755264 DOI: 10.1186/S13287-019-1147-7  0.331
2019 Marsden MD, Zack JA. HIV cure strategies: a complex approach for a complicated viral reservoir? Future Virology. 14: 5-8. DOI: 10.2217/Fvl-2018-0205  0.478
2018 Marsden MD, Wu X, Navab SM, Loy BA, Schrier AJ, DeChristopher BA, Shimizu AJ, Hardman CT, Ho S, Ramirez CM, Wender PA, Zack JA. Characterization of designed, synthetically accessible bryostatin analog HIV latency reversing agents. Virology. 520: 83-93. PMID 29800728 DOI: 10.1016/J.Virol.2018.05.006  0.621
2018 Zhen A, Peterson CW, Carrillo MA, Reddy SS, Youn CS, Lam BB, Chang NY, Martin HA, Rick JW, Kim J, Neel NC, Rezek VK, Kamata M, Chen ISY, Zack JA, et al. Correction: Long-term persistence and function of hematopoietic stem cell-derived chimeric antigen receptor T cells in a nonhuman primate model of HIV/AIDS. Plos Pathogens. 14: e1006891. PMID 29529058 DOI: 10.1371/journal.ppat.1006891  0.419
2017 Zhen A, Peterson CW, Carrillo MA, Reddy SS, Youn CS, Lam BB, Chang NY, Martin HA, Rick JW, Kim J, Neel NC, Rezek VK, Kamata M, Chen ISY, Zack JA, et al. Long-term persistence and function of hematopoietic stem cell-derived chimeric antigen receptor T cells in a nonhuman primate model of HIV/AIDS. Plos Pathogens. 13: e1006753. PMID 29284044 DOI: 10.1371/Journal.Ppat.1006753  0.581
2017 Hazim RA, Karumbayaram S, Jiang M, Dimashkie A, Lopes VS, Li D, Burgess BL, Vijayaraj P, Alva-Ornelas JA, Zack JA, Kohn DB, Gomperts BN, Pyle AD, Lowry WE, Williams DS. Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization. Stem Cell Research & Therapy. 8: 217. PMID 28969679 DOI: 10.1186/S13287-017-0652-9  0.367
2017 Marsden MD, Loy BA, Wu X, Ramirez CM, Schrier AJ, Murray D, Shimizu A, Ryckbosch SM, Near KE, Chun TW, Wender PA, Zack JA. In vivo activation of latent HIV with a synthetic bryostatin analog effects both latent cell "kick" and "kill" in strategy for virus eradication. Plos Pathogens. 13: e1006575. PMID 28934369 DOI: 10.1371/Journal.Ppat.1006575  0.653
2017 Carrillo MA, Zhen A, Zack JA, Kitchen SG. New approaches for the enhancement of chimeric antigen receptors for the treatment of HIV. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 28755872 DOI: 10.1016/J.Trsl.2017.07.002  0.595
2017 Marsden MD, Zack JA. Humanized Mouse Models for Human Immunodeficiency Virus Infection. Annual Review of Virology. PMID 28746819 DOI: 10.1146/Annurev-Virology-101416-041703  0.569
2016 Kitchen SG, Zack JA. Engineering HIV-Specific Immunity with Chimeric Antigen Receptors. Aids Patient Care and Stds. 30: 556-561. PMID 27905838 DOI: 10.1089/Apc.2016.0239  0.612
2016 Zhen A, Rezek V, Youn C, Rick J, Lam B, Chang N, Zack J, Kamata M, Kitchen S. Stem-cell Based Engineered Immunity Against HIV Infection in the Humanized Mouse Model. Journal of Visualized Experiments : Jove. PMID 27404517 DOI: 10.3791/54048  0.589
2016 Deeks SG, Lewin SR, Ross AL, Ananworanich J, Benkirane M, Cannon P, Chomont N, Douek D, Lifson JD, Lo YR, Kuritzkes D, Margolis D, Mellors J, Persaud D, Tucker JD, ... ... Zack J, et al. International AIDS Society global scientific strategy: towards an HIV cure 2016. Nature Medicine. PMID 27400264 DOI: 10.1038/Nm.4108  0.502
2016 Ali A, Kitchen SG, Chen IS, Ng HL, Zack JA, Yang OO. HIV-1-Specific Chimeric Antigen Receptors Based on Broadly-Neutralizing Antibodies. Journal of Virology. PMID 27226366 DOI: 10.1128/Jvi.00805-16  0.579
2016 Dou DR, Calvanese V, Sierra MI, Nguyen AT, Minasian A, Saarikoski P, Sasidharan R, Ramirez CM, Zack JA, Crooks GM, Galic Z, Mikkola HK. Medial HOXA genes demarcate haematopoietic stem cell fate during human development. Nature Cell Biology. PMID 27183470 DOI: 10.1038/Ncb3354  0.397
2015 Marsden MD, Zack JA. Experimental Approaches for Eliminating Latent HIV. Forum On Immunopathological Diseases and Therapeutics. 6: 91-99. PMID 28191361 DOI: 10.1615/Forumimmundisther.2016015242  0.622
2015 Akkina RK, Allam A, Balazs AB, Blankson J, Burnett JC, Casares S, Garcia JV, Hasenkrug K, Kashanchi F, Kitchen S, Klein F, Kumar P, Luster AD, Poluektova LY, Rao M, ... ... Zack JA, et al. Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary. Aids Research and Human Retroviruses. PMID 26670361 DOI: 10.1089/Aid.2015.0258  0.513
2015 Sanchez DJ, Miranda D, Marsden MD, Dizon TM, Bontemps JR, Davila SJ, Del Mundo LE, Ha T, Senaati A, Zack JA, Cheng G. Disruption of Type I Interferon Induction by HIV Infection of T Cells. Plos One. 10: e0137951. PMID 26375588 DOI: 10.1371/Journal.Pone.0137951  0.586
2015 Kim SG, Lowe EL, Dixit D, Seyeon Youn C, Kim IJ, Jung JB, Rovner R, Zack JA, Vatakis DN. Cocaine-mediated impact on HIV infection in humanized BLT mice. Scientific Reports. 5: 10010. PMID 26084721 DOI: 10.1038/Srep10010  0.501
2015 Zhen A, Kamata M, Rezek V, Rick J, Levin B, Kasparian S, Chen IS, Yang OO, Zack JA, Kitchen SG. HIV-specific Immunity Derived From Chimeric Antigen Receptor-engineered Stem Cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 1358-67. PMID 26050990 DOI: 10.1038/Mt.2015.102  0.63
2015 McCracken MN, Vatakis DN, Dixit D, McLaughlin J, Zack JA, Witte ON. Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging. The Journal of Clinical Investigation. 125: 1815-26. PMID 25822024 DOI: 10.1172/Jci77326  0.41
2015 Menon T, Firth AL, Scripture-Adams DD, Galic Z, Qualls SJ, Gilmore WB, Ke E, Singer O, Anderson LS, Bornzin AR, Alexander IE, Zack JA, Verma IM. Lymphoid regeneration from gene-corrected SCID-X1 subject-derived iPSCs. Cell Stem Cell. 16: 367-72. PMID 25772073 DOI: 10.1016/J.Stem.2015.02.005  0.789
2015 Shimizu S, Ringpis GE, Marsden MD, Cortado RV, Wilhalme HM, Elashoff D, Zack JA, Chen IS, An DS. RNAi-Mediated CCR5 Knockdown Provides HIV-1 Resistance to Memory T Cells in Humanized BLT Mice. Molecular Therapy. Nucleic Acids. 4: e227. PMID 25689223 DOI: 10.1038/Mtna.2015.3  0.602
2015 Marsden MD, Zack JA. Studies of retroviral infection in humanized mice. Virology. 479: 297-309. PMID 25680625 DOI: 10.1016/J.Virol.2015.01.017  0.493
2015 Marsden MD, Zack JA. Double trouble: HIV latency and CTL escape. Cell Host & Microbe. 17: 141-2. PMID 25674977 DOI: 10.1016/J.Chom.2015.01.008  0.51
2015 Pise-Masison CA, Nixon CC, de Castro Amarante MF, Parks RW, McKinnon K, Caruso B, Galli V, Jacobson S, Zack J, Franchini G. Detection of HTLV-1 replication and CD4+ proliferation in the humanized BLT mouse model Retrovirology. 12. DOI: 10.1186/1742-4690-12-S1-O39  0.462
2015 Zhen A, Kamata M, Rezek V, Rick J, Levin B, Kasparian S, Chen ISY, Yang OO, Zack JA, Kitchen SG. HIV-specific Immunity Derived From Chimeric Antigen Receptor-engineered Stem Cells Molecular Therapy. DOI: 10.1038/mt.2015.102  0.379
2015 Dou DR, Calvanese V, Sierra MI, Sasidharan R, Zack JA, Crooks GM, Galic Z, Mikkola H. Medial HOXA gene expression is required for establishing “stemness” in human HSCs Experimental Hematology. 43: S48. DOI: 10.1016/J.Exphem.2015.06.064  0.301
2014 Marsden MD, Zack JA. Neutralizing the HIV reservoir. Cell. 158: 971-2. PMID 25171398 DOI: 10.1016/J.Cell.2014.08.010  0.509
2014 Buehler DC, Marsden MD, Shen S, Toso DB, Wu X, Loo JA, Zhou ZH, Kickhoefer VA, Wender PA, Zack JA, Rome LH. Bioengineered vaults: self-assembling protein shell-lipophilic core nanoparticles for drug delivery. Acs Nano. 8: 7723-32. PMID 25061969 DOI: 10.1021/Nn5002694  0.379
2014 Zhen A, Krutzik SR, Levin BR, Kasparian S, Zack JA, Kitchen SG. CD4 ligation on human blood monocytes triggers macrophage differentiation and enhances HIV infection. Journal of Virology. 88: 9934-46. PMID 24942581 DOI: 10.1128/Jvi.00616-14  0.438
2014 Chodon T, Comin-Anduix B, Chmielowski B, Koya RC, Wu Z, Auerbach M, Ng C, Avramis E, Seja E, Villanueva A, McCannel TA, Ishiyama A, Czernin J, Radu CG, Wang X, ... ... Zack JA, et al. Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 2457-65. PMID 24634374 DOI: 10.1158/1078-0432.Ccr-13-3017  0.383
2013 Awe JP, Lee PC, Ramathal C, Vega-Crespo A, Durruthy-Durruthy J, Cooper A, Karumbayaram S, Lowry WE, Clark AT, Zack JA, Sebastiano V, Kohn DB, Pyle AD, Martin MG, Lipshutz GS, et al. Generation and characterization of transgene-free human induced pluripotent stem cells and conversion to putative clinical-grade status. Stem Cell Research & Therapy. 4: 87. PMID 23890092 DOI: 10.1186/Scrt246  0.399
2013 Nixon CC, Vatakis DN, Reichelderfer SN, Dixit D, Kim SG, Uittenbogaart CH, Zack JA. HIV-1 infection of hematopoietic progenitor cells in vivo in humanized mice. Blood. 122: 2195-204. PMID 23886835 DOI: 10.1182/Blood-2013-04-496950  0.588
2013 Kim SG, Jung JB, Dixit D, Rovner R, Zack JA, Baldwin GC, Vatakis DN. Cocaine exposure enhances permissiveness of quiescent T cells to HIV infection. Journal of Leukocyte Biology. 94: 835-43. PMID 23817564 DOI: 10.1189/Jlb.1112566  0.564
2013 Beans EJ, Fournogerakis D, Gauntlett C, Heumann LV, Kramer R, Marsden MD, Murray D, Chun TW, Zack JA, Wender PA. Highly potent, synthetically accessible prostratin analogs induce latent HIV expression in vitro and ex vivo. Proceedings of the National Academy of Sciences of the United States of America. 110: 11698-703. PMID 23812750 DOI: 10.1073/Pnas.1302634110  0.659
2013 Marsden MD, Zack JA. HIV/AIDS eradication. Bioorganic & Medicinal Chemistry Letters. 23: 4003-10. PMID 23735743 DOI: 10.1016/J.Bmcl.2013.05.032  0.597
2013 Zack JA, Kim SG, Vatakis DN. HIV restriction in quiescent CD4⁺ T cells. Retrovirology. 10: 37. PMID 23557201 DOI: 10.1186/1742-4690-10-37  0.654
2013 Vatakis DN, Arumugam B, Kim SG, Bristol G, Yang O, Zack JA. Introduction of exogenous T-cell receptors into human hematopoietic progenitors results in exclusion of endogenous T-cell receptor expression. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1055-63. PMID 23481324 DOI: 10.1038/Mt.2013.28  0.445
2013 Liu SY, Aliyari R, Chikere K, Li G, Marsden MD, Smith JK, Pernet O, Guo H, Nusbaum R, Zack JA, Freiberg AN, Su L, Lee B, Cheng G. Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol. Immunity. 38: 92-105. PMID 23273844 DOI: 10.1016/J.Immuni.2012.11.005  0.524
2012 Vatakis DN, Bristol GC, Kim SG, Levin B, Liu W, Radu CG, Kitchen SG, Zack JA. Using the BLT humanized mouse as a stem cell based gene therapy tumor model. Journal of Visualized Experiments : Jove. e4181. PMID 23271478 DOI: 10.3791/4181  0.507
2012 Karumbayaram S, Lee P, Azghadi SF, Cooper AR, Patterson M, Kohn DB, Pyle A, Clark A, Byrne J, Zack JA, Plath K, Lowry WE. From skin biopsy to neurons through a pluripotent intermediate under Good Manufacturing Practice protocols. Stem Cells Translational Medicine. 1: 36-43. PMID 23197638 DOI: 10.5966/Sctm.2011-0001  0.35
2012 DeChristopher BA, Loy BA, Marsden MD, Schrier AJ, Zack JA, Wender PA. Designed, synthetically accessible bryostatin analogues potently induce activation of latent HIV reservoirs in vitro. Nature Chemistry. 4: 705-10. PMID 22914190 DOI: 10.1038/Nchem.1395  0.522
2012 Marsden MD, Krogstad PA, Zack JA. Virological evidence supporting the use of raltegravir in HIV post-exposure prophylaxis regimens. Antiviral Therapy. 17: 1375-9. PMID 22820096 DOI: 10.3851/Imp2255  0.493
2012 Kitchen SG, Levin BR, Bristol G, Rezek V, Kim S, Aguilera-Sandoval C, Balamurugan A, Yang OO, Zack JA. In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells. Plos Pathogens. 8: e1002649. PMID 22511873 DOI: 10.1371/Journal.Ppat.1002649  0.649
2012 Marsden MD, Kovochich M, Suree N, Shimizu S, Mehta R, Cortado R, Bristol G, An DS, Zack JA. HIV latency in the humanized BLT mouse. Journal of Virology. 86: 339-47. PMID 22072769 DOI: 10.1128/Jvi.06366-11  0.828
2012 Dou DR, Minasian A, Sierra MI, Saarikoski P, Xu J, Orkin SH, Prashad SL, Magnusson M, Zack JA, Crooks GM, Galic Z, Mikkola HKA. Inability to Express HOXA Cluster and BCL11A Genes Compromises Self-Renewal and Multipotency of hESC-Derived Hematopoietic Cells Blood. 120: 1190-1190. DOI: 10.1182/Blood.V120.21.1190.1190  0.414
2011 Vatakis DN, Koya RC, Nixon CC, Wei L, Kim SG, Avancena P, Bristol G, Baltimore D, Kohn DB, Ribas A, Radu CG, Galic Z, Zack JA. Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 108: E1408-16. PMID 22123951 DOI: 10.1073/Pnas.1115050108  0.456
2011 Marban C, Su T, Ferrari R, Li B, Vatakis D, Pellegrini M, Zack JA, Rohr O, Kurdistani SK. Genome-wide binding map of the HIV-1 Tat protein to the human genome. Plos One. 6: e26894. PMID 22073215 DOI: 10.1371/Journal.Pone.0026894  0.428
2011 Marsden MD, Burke BP, Zack JA. HIV latency is influenced by regions of the viral genome outside of the long terminal repeats and regulatory genes. Virology. 417: 394-9. PMID 21777932 DOI: 10.1016/J.Virol.2011.06.024  0.787
2011 Mitsuyasu RT, Zack JA, Macpherson JL, Symonds GP. Phase I/II Clinical Trials Using Gene-Modified Adult Hematopoietic Stem Cells for HIV: Lessons Learnt. Stem Cells International. 2011: 393698. PMID 21716651 DOI: 10.4061/2011/393698  0.508
2011 Marsden MD, Avancena P, Kitchen CM, Hubbard T, Zack JA. Single mutations in HIV integrase confer high-level resistance to raltegravir in primary human macrophages. Antimicrobial Agents and Chemotherapy. 55: 3696-702. PMID 21628534 DOI: 10.1128/Aac.00566-11  0.522
2011 Kovochich M, Marsden MD, Zack JA. Activation of latent HIV using drug-loaded nanoparticles. Plos One. 6: e18270. PMID 21483687 DOI: 10.1371/Journal.Pone.0018270  0.816
2011 Kitchen SG, Zack JA. Stem cell-based approaches to treating HIV infection. Current Opinion in Hiv and Aids. 6: 68-73. PMID 21242896 DOI: 10.1097/Coh.0B013E3283412370  0.569
2010 Marsden MD, Zack JA. Establishment and maintenance of HIV latency: model systems and opportunities for intervention. Future Virology. 5: 97-109. PMID 21318097 DOI: 10.2217/Fvl.09.70  0.603
2010 Tchieu J, Kuoy E, Chin MH, Trinh H, Patterson M, Sherman SP, Aimiuwu O, Lindgren A, Hakimian S, Zack JA, Clark AT, Pyle AD, Lowry WE, Plath K. Female human iPSCs retain an inactive X chromosome. Cell Stem Cell. 7: 329-42. PMID 20727844 DOI: 10.1016/J.Stem.2010.06.024  0.325
2010 Vatakis DN, Nixon CC, Zack JA. Quiescent T cells and HIV: an unresolved relationship. Immunologic Research. 48: 110-21. PMID 20725862 DOI: 10.1007/S12026-010-8171-0  0.648
2010 Epeldegui M, Thapa DR, De la Cruz J, Kitchen S, Zack JA, Martínez-Maza O. CD40 ligand (CD154) incorporated into HIV virions induces activation-induced cytidine deaminase (AID) expression in human B lymphocytes. Plos One. 5: e11448. PMID 20625427 DOI: 10.1371/Journal.Pone.0011448  0.562
2010 Brown HJ, Peng L, Harada JN, Walker JR, Cole S, Lin SF, Zack JA, Chanda SK, Sun R. Gene expression and transcription factor profiling reveal inhibition of transcription factor cAMP-response element-binding protein by gamma-herpesvirus replication and transcription activator. The Journal of Biological Chemistry. 285: 25139-53. PMID 20516076 DOI: 10.1074/Jbc.M110.137737  0.368
2010 Sundaravaradan V, Mehta R, Harris DT, Zack JA, Ahmad N. Differential expression and interaction of host factors augment HIV-1 gene expression in neonatal mononuclear cells Virology. 400: 32-43. PMID 20138641 DOI: 10.1016/J.Virol.2010.01.018  0.528
2010 Shimizu S, Hong P, Arumugam B, Pokomo L, Boyer J, Koizumi N, Kittipongdaja P, Chen A, Bristol G, Galic Z, Zack JA, Yang O, Chen IS, Lee B, An DS. A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model. Blood. 115: 1534-44. PMID 20018916 DOI: 10.1182/Blood-2009-04-215855  0.581
2010 Kitchen SG, Zack JA. Genetic vaccination: Engineering antiviral T-cell immunity through stem cells Hiv Therapy. 4: 123-126. DOI: 10.2217/Hiv.10.9  0.549
2009 Kitchen SG, Bennett M, Gali? Z, Kim J, Xu Q, Young A, Lieberman A, Joseph A, Goldstein H, Ng H, Yang O, Zack JA. Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice. Plos One. 4: e8208. PMID 19997617 DOI: 10.1371/Journal.Pone.0008208  0.633
2009 Vatakis DN, Kim S, Kim N, Chow SA, Zack JA. Human immunodeficiency virus integration efficiency and site selection in quiescent CD4+ T cells. Journal of Virology. 83: 6222-33. PMID 19369341 DOI: 10.1128/Jvi.00356-09  0.587
2009 Bernstein HB, Wang G, Plasterer MC, Zack JA, Ramasastry P, Mumenthaler SM, Kitchen CM. CD4+ NK cells can be productively infected with HIV, leading to downregulation of CD4 expression and changes in function. Virology. 387: 59-66. PMID 19251297 DOI: 10.1016/J.Virol.2009.01.044  0.61
2009 Conway AE, Lindgren A, Galic Z, Pyle AD, Wu H, Zack JA, Pelligrini M, Teitell MA, Clark AT. A self-renewal program controls the expansion of genetically unstable cancer stem cells in pluripotent stem cell-derived tumors. Stem Cells (Dayton, Ohio). 27: 18-28. PMID 19224508 DOI: 10.1634/Stemcells.2008-0529  0.36
2009 Mitsuyasu RT, Merigan TC, Carr A, Zack JA, Winters MA, Workman C, Bloch M, Lalezari J, Becker S, Thornton L, Akil B, Khanlou H, Finlayson R, McFarlane R, Smith DE, et al. Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells. Nature Medicine. 15: 285-92. PMID 19219022 DOI: 10.1038/Nm.1932  0.542
2009 Vatakis DN, Nixon CC, Bristol G, Zack JA. Differentially stimulated CD4+ T cells display altered human immunodeficiency virus infection kinetics: implications for the efficacy of antiviral agents. Journal of Virology. 83: 3374-8. PMID 19129455 DOI: 10.1128/Jvi.02161-08  0.552
2009 Marsden MD, Zack JA. Eradication of HIV: current challenges and new directions. The Journal of Antimicrobial Chemotherapy. 63: 7-10. PMID 18984648 DOI: 10.1093/Jac/Dkn455  0.609
2009 Galić Z, Kitchen SG, Subramanian A, Bristol G, Marsden MD, Balamurugan A, Kacena A, Yang O, Zack JA. Generation of T lineage cells from human embryonic stem cells in a feeder free system. Stem Cells (Dayton, Ohio). 27: 100-7. PMID 18974209 DOI: 10.1634/Stemcells.2008-0813  0.463
2009 Epeldegui M, Kitchen S, De La Cruz J, Zack J, Martinez-Maza O. HIV induces the expression of activation-induced cytidine deaminase (AICDA) in B cells through a direct interaction between virion-associated CD40L and CD40 Infectious Agents and Cancer. 4. DOI: 10.1186/1750-9378-4-S2-O11  0.549
2008 Miranda-Carboni GA, Krum SA, Yee K, Nava M, Deng QE, Pervin S, Collado-Hidalgo A, Galic Z, Zack JA, Nakayama K, Nakayama KI, Lane TF. A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors. Genes & Development. 22: 3121-34. PMID 19056892 DOI: 10.1101/Gad.1692808  0.385
2008 Marsden MD, Xu J, Hamer D, Zack JA. Short communication: Activating stimuli enhance immunotoxin-mediated killing of HIV-infected macrophages. Aids Research and Human Retroviruses. 24: 1399-404. PMID 19000022 DOI: 10.1089/Aid.2008.0082  0.605
2008 Marsden MD, Xu J, Hamer D, Zack JA. Activating stimuli enhance immunotoxin-mediated killing of HIV-infected macrophages Aids Research and Human Retroviruses. 24: 1399-1404. DOI: 10.1089/aid.2008.0082  0.439
2007 Burke B, Brown HJ, Marsden MD, Bristol G, Vatakis DN, Zack JA. Primary cell model for activation-inducible human immunodeficiency virus. Journal of Virology. 81: 7424-34. PMID 17475639 DOI: 10.1128/Jvi.02838-06  0.829
2007 Marsden MD, Zack JA. Human immunodeficiency virus bearing a disrupted central DNA flap is pathogenic in vivo. Journal of Virology. 81: 6146-50. PMID 17392373 DOI: 10.1128/Jvi.00203-07  0.547
2007 Hryniewicz A, Price DA, Moniuszko M, Boasso A, Edghill-Spano Y, West SM, Venzon D, Vaccari M, Tsai WP, Tryniszewska E, Nacsa J, Villinger F, Ansari AA, Trindade CJ, Morre M, ... ... Zack JA, et al. Interleukin-15 but not interleukin-7 abrogates vaccine-induced decrease in virus level in simian immunodeficiency virus mac251-infected macaques. Journal of Immunology (Baltimore, Md. : 1950). 178: 3492-504. PMID 17339444 DOI: 10.4049/Jimmunol.178.6.3492  0.804
2007 Vatakis DN, Bristol G, Wilkinson TA, Chow SA, Zack JA. Immediate activation fails to rescue efficient human immunodeficiency virus replication in quiescent CD4+ T cells. Journal of Virology. 81: 3574-82. PMID 17229711 DOI: 10.1128/Jvi.02569-06  0.626
2006 Brown HJ, Zack JA. Animal models of HIV-1 latency and persistence. Current Opinion in Hiv and Aids. 1: 103-7. PMID 19372792 DOI: 10.1097/01.Coh.0000203833.16597.E3  0.582
2006 Bernstein HB, Plasterer MC, Schiff SE, Kitchen CM, Kitchen S, Zack JA. CD4 expression on activated NK cells: ligation of CD4 induces cytokine expression and cell migration. Journal of Immunology (Baltimore, Md. : 1950). 177: 3669-76. PMID 16951326 DOI: 10.4049/Jimmunol.177.6.3669  0.395
2006 Galic Z, Kitchen SG, Kacena A, Subramanian A, Burke B, Cortado R, Zack JA. T lineage differentiation from human embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 11742-7. PMID 16844782 DOI: 10.1073/Pnas.0604244103  0.738
2006 Arlen PA, Brooks DG, Gao LY, Vatakis D, Brown HJ, Zack JA. Rapid expression of human immunodeficiency virus following activation of latently infected cells. Journal of Virology. 80: 1599-603. PMID 16415036 DOI: 10.1128/Jvi.80.3.1599-1603.2006  0.802
2006 Groszer M, Erickson R, Scripture-Adams DD, Dougherty JD, Le Belle J, Zack JA, Geschwind DH, Liu X, Kornblum HI, Wu H. PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry. Proceedings of the National Academy of Sciences of the United States of America. 103: 111-6. PMID 16373498 DOI: 10.1073/Pnas.0509939103  0.778
2005 Widney DP, Breen EC, Boscardin WJ, Kitchen SG, Alcantar JM, Smith JB, Zack JA, Detels R, Martínez-Maza O. Serum levels of the homeostatic B cell chemokine, CXCL13, are elevated during HIV infection. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 25: 702-6. PMID 16318584 DOI: 10.1089/Jir.2005.25.702  0.564
2005 Brooks DG, Cohen MD, Jamieson BD, Poon B, Kitchen SG, Chow SA, Chen IS, Zack JA, Koka PS. Rapid size dependent deletion of foreign gene sequences inserted into attenuated HIV-1 upon infection in vivo: implications for vaccine development. Current Hiv Research. 3: 377-92. PMID 16250884 DOI: 10.2174/157016205774370410  0.526
2005 Chang M, Brown HJ, Collado-Hidalgo A, Arevalo JM, Galic Z, Symensma TL, Tanaka L, Deng H, Zack JA, Sun R, Cole SW. beta-Adrenoreceptors reactivate Kaposi's sarcoma-associated herpesvirus lytic replication via PKA-dependent control of viral RTA. Journal of Virology. 79: 13538-47. PMID 16227274 DOI: 10.1128/Jvi.79.21.13538-13547.2005  0.363
2005 Brown HJ, McBride WH, Zack JA, Sun R. Prostratin and bortezomib are novel inducers of latent Kaposi's sarcoma-associated herpesvirus. Antiviral Therapy. 10: 745-51. PMID 16218174  0.305
2005 Kitchen SG, Whitmire JK, Jones NR, Galic Z, Kitchen CM, Ahmed R, Zack JA. The CD4 molecule on CD8+ T lymphocytes directly enhances the immune response to viral and cellular antigens. Proceedings of the National Academy of Sciences of the United States of America. 102: 3794-9. PMID 15731353 DOI: 10.1073/Pnas.0406603102  0.4
2004 Chen H, Zha J, Gowans RE, Camargo P, Nishitani J, McQuirter JL, Cole SW, Zack JA, Liu X. Alcohol enhances HIV type 1 infection in normal human oral keratinocytes by up-regulating cell-surface CXCR4 coreceptor. Aids Research and Human Retroviruses. 20: 513-9. PMID 15186526 DOI: 10.1089/088922204323087769  0.693
2004 Kitchen SG, Jones NR, LaForge S, Whitmire JK, Vu BA, Galic Z, Brooks DG, Brown SJ, Kitchen CM, Zack JA. CD4 on CD8(+) T cells directly enhances effector function and is a target for HIV infection. Proceedings of the National Academy of Sciences of the United States of America. 101: 8727-32. PMID 15173593 DOI: 10.1073/Pnas.0401500101  0.485
2004 Richlin VA, Arevalo JM, Zack JA, Cole SW. Stress-induced enhancement of NF-kappaB DNA-binding in the peripheral blood leukocyte pool: effects of lymphocyte redistribution. Brain, Behavior, and Immunity. 18: 231-7. PMID 15050650 DOI: 10.1016/J.Bbi.2003.08.001  0.35
2004 Amado RG, Mitsuyasu RT, Rosenblatt JD, Ngok FK, Bakker A, Cole S, Chorn N, Lin LS, Bristol G, Boyd MP, MacPherson JL, Fanning GC, Todd AV, Ely JA, Zack JA, et al. Anti-human immunodeficiency virus hematopoietic progenitor cell-delivered ribozyme in a phase I study: myeloid and lymphoid reconstitution in human immunodeficiency virus type-1-infected patients. Human Gene Therapy. 15: 251-62. PMID 15018734 DOI: 10.1089/104303404322886101  0.64
2004 Moore JP, Kitchen SG, Pugach P, Zack JA. The CCR5 and CXCR4 coreceptors--central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection. Aids Research and Human Retroviruses. 20: 111-26. PMID 15000703 DOI: 10.1089/088922204322749567  0.583
2004 Burton DR, Desrosiers RC, Doms RW, Feinberg MB, Gallo RC, Hahn B, Hoxie JA, Hunter E, Korber B, Landay A, Lederman MM, Lieberman J, McCune JM, Moore JP, Nathanson N, ... ... Zack JA, et al. Public health. A sound rationale needed for phase III HIV-1 vaccine trials. Science (New York, N.Y.). 303: 316. PMID 14726576 DOI: 10.1126/Science.1094620  0.311
2004 Ali A, Lubong R, Ng H, Brooks DG, Zack JA, Yang OO. Impacts of epitope expression kinetics and class I downregulation on the antiviral activity of human immunodeficiency virus type 1-specific cytotoxic T lymphocytes. Journal of Virology. 78: 561-7. PMID 14694087 DOI: 10.1128/Jvi.78.2.561-567.2004  0.611
2003 Cole SW, Kemeny ME, Fahey JL, Zack JA, Naliboff BD. Psychological risk factors for HIV pathogenesis: mediation by the autonomic nervous system. Biological Psychiatry. 54: 1444-56. PMID 14675810 DOI: 10.1016/S0006-3223(02)01888-7  0.513
2003 Brooks DG, Arlen PA, Gao L, Kitchen CM, Zack JA. Identification of T cell-signaling pathways that stimulate latent HIV in primary cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 12955-60. PMID 14569007 DOI: 10.1073/Pnas.2233345100  0.832
2003 Brooks DG, Hamer DH, Arlen PA, Gao L, Bristol G, Kitchen CM, Berger EA, Zack JA. Molecular characterization, reactivation, and depletion of latent HIV. Immunity. 19: 413-23. PMID 14499116 DOI: 10.1016/S1074-7613(03)00236-X  0.845
2003 Liu X, Zha J, Nishitani J, Chen H, Zack JA. HIV-1 infection in peripheral blood lymphocytes (PBLs) exposed to alcohol. Virology. 307: 37-44. PMID 12667812 DOI: 10.1016/S0042-6822(02)00031-4  0.664
2003 Liu X, Zha J, Chen H, Nishitani J, Camargo P, Cole SW, Zack JA. Human immunodeficiency virus type 1 infection and replication in normal human oral keratinocytes. Journal of Virology. 77: 3470-6. PMID 12610122 DOI: 10.1128/Jvi.77.6.3470-3476.2003  0.733
2003 Koka PS, Brooks DG, Razai A, Kitchen CM, Zack JA. HIV type 1 infection alters cytokine mRNA expression in thymus. Aids Research and Human Retroviruses. 19: 1-12. PMID 12581511 DOI: 10.1089/08892220360473916  0.555
2002 Scripture-Adams DD, Brooks DG, Korin YD, Zack JA. Interleukin-7 induces expression of latent human immunodeficiency virus type 1 with minimal effects on T-cell phenotype. Journal of Virology. 76: 13077-82. PMID 12438635 DOI: 10.1128/Jvi.76.24.13077-13082.2002  0.845
2002 Korin YD, Brooks DG, Brown S, Korotzer A, Zack JA. Effects of prostratin on T-cell activation and human immunodeficiency virus latency. Journal of Virology. 76: 8118-23. PMID 12134017 DOI: 10.1128/Jvi.76.16.8118-8123.2002  0.678
2002 Roth MD, Tashkin DP, Choi R, Jamieson BD, Zack JA, Baldwin GC. Cocaine enhances human immunodeficiency virus replication in a model of severe combined immunodeficient mice implanted with human peripheral blood leukocytes. The Journal of Infectious Diseases. 185: 701-5. PMID 11865430 DOI: 10.1086/339012  0.47
2002 Cole AM, Hong T, Boo LM, Nguyen T, Zhao C, Bristol G, Zack JA, Waring AJ, Yang OO, Lehrer RI. Retrocyclin: a primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1. Proceedings of the National Academy of Sciences of the United States of America. 99: 1813-8. PMID 11854483 DOI: 10.1073/Pnas.052706399  0.553
2002 Brooks DG, Zack JA. Effect of latent human immunodeficiency virus infection on cell surface phenotype. Journal of Virology. 76: 1673-81. PMID 11799162 DOI: 10.1128/Jvi.76.4.1673-1681.2002  0.671
2002 Kitchen SG, LaForge S, Patel VP, Kitchen CM, Miceli MC, Zack JA. Activation of CD8 T cells induces expression of CD4, which functions as a chemotactic receptor. Blood. 99: 207-12. PMID 11756173 DOI: 10.1182/Blood.V99.1.207  0.356
2001 Groszer M, Erickson R, Scripture-Adams DD, Lesche R, Trumpp A, Zack JA, Kornblum HI, Liu X, Wu H. Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo. Science (New York, N.Y.). 294: 2186-9. PMID 11691952 DOI: 10.1126/Science.1065518  0.781
2001 Cole SW, Naliboff BD, Kemeny ME, Griswold MP, Fahey JL, Zack JA. Impaired response to HAART in HIV-infected individuals with high autonomic nervous system activity. Proceedings of the National Academy of Sciences of the United States of America. 98: 12695-700. PMID 11675501 DOI: 10.1073/Pnas.221134198  0.575
2001 Eckstein DA, Penn ML, Korin YD, Scripture-Adams DD, Zack JA, Kreisberg JF, Roederer M, Sherman MP, Chin PS, Goldsmith MA. HIV-1 actively replicates in naive CD4(+) T cells residing within human lymphoid tissues. Immunity. 15: 671-82. PMID 11672548 DOI: 10.1016/S1074-7613(01)00217-5  0.856
2001 Gorry PR, Bristol G, Zack JA, Ritola K, Swanstrom R, Birch CJ, Bell JE, Bannert N, Crawford K, Wang H, Schols D, De Clercq E, Kunstman K, Wolinsky SM, Gabuzda D. Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity. Journal of Virology. 75: 10073-89. PMID 11581376 DOI: 10.1128/Jvi.75.21.10073-10089.2001  0.494
2001 Sullivan YB, Landay AL, Zack JA, Kitchen SG, Al-Harthi L. Upregulation of CD4 on CD8+ T cells: CD4dimCD8bright T cells constitute an activated phenotype of CD8+ T cells. Immunology. 103: 270-80. PMID 11454056 DOI: 10.1046/J.1365-2567.2001.01243.X  0.378
2001 Brooks DG, Kitchen SG, Kitchen CM, Scripture-Adams DD, Zack JA. Generation of HIV latency during thymopoiesis. Nature Medicine. 7: 459-64. PMID 11283673 DOI: 10.1038/86531  0.864
2000 Uittenbogaart CH, Boscardin WJ, Anisman-Posner DJ, Koka PS, Bristol G, Zack JA. Effect of cytokines on HIV-induced depletion of thymocytes in vivo Aids. 14: 1317-1325. PMID 10930145 DOI: 10.1097/00002030-200007070-00003  0.397
2000 Camerini D, Hua-Poo S, Gamez-Torre G, Johnson ML, Zack JA, Chen ISY. Human immunodeficiency virus type 1 pathogenesis in SCID-hu mice correlates with syncytium-inducing phenotype and viral replication Journal of Virology. 74: 3196-3204. PMID 10708436 DOI: 10.1128/Jvi.74.7.3196-3204.2000  0.593
2000 Kitchen SG, Killian S, Giorgi JV, Zack JA. Functional reconstitution of thymopoiesis after human immunodeficiency virus infection Journal of Virology. 74: 2943-2948. PMID 10684316 DOI: 10.1128/Jvi.74.6.2943-2948.2000  0.519
2000 Schmid I, Cole SW, Zack JA, Giorgi JV. Measurement of lymphocyte subset proliferation by three-color immunofluorescence and DNA flow cytometry Journal of Immunological Methods. 235: 121-131. PMID 10675764 DOI: 10.1016/S0022-1759(99)00225-2  0.313
1999 Koka PS, Jamieson BD, Brooks DG, Zack JA. Human immunodeficiency virus type 1-induced hematopoietic inhibition is independent of productive infection of progenitor cells in vivo. Journal of Virology. 73: 9089-97. PMID 10516015 DOI: 10.1128/Jvi.73.11.9089-9097.1999  0.639
1999 Amado RG, Mitsuyasu RT, Symonds G, Rosenblatt JD, Zack J, Sun LQ, Miller M, Ely J, Gerlach W. A phase I trial of autologous CD34+ hematopoietic progenitor cells transduced with an anti-HIV ribozyme. Human Gene Therapy. 10: 2255-70. PMID 10498256 DOI: 10.1089/10430349950017239  0.493
1999 Korin YD, Zack JA. Nonproductive human immunodeficiency virus type 1 infection in nucleoside-treated G0 lymphocytes. Journal of Virology. 73: 6526-32. PMID 10400748 DOI: 10.1128/Jvi.73.8.6526-6532.1999  0.627
1999 Amado RG, Jamieson BD, Cortado R, Cole SW, Zack JA. Reconstitution of human thymic implants is limited by human immunodeficiency virus breakthrough during antiretroviral therapy. Journal of Virology. 73: 6361-9. PMID 10400728 DOI: 10.1128/Jvi.73.8.6361-6369.1999  0.631
1999 Jamieson BD, Douek DC, Killian S, Hultin LE, Scripture-Adams DD, Giorgi JV, Marelli D, Koup RA, Zack JA. Generation of functional thymocytes in the human adult. Immunity. 10: 569-75. PMID 10367902 DOI: 10.1016/S1074-7613(00)80056-4  0.805
1999 Amado RG, Mitsuyasu RT, Zack JA. Gene therapy for the treatment of AIDS: animal models and human clinical experience. Frontiers in Bioscience : a Journal and Virtual Library. 4: D468-75. PMID 10331991 DOI: 10.2741/Amado  0.513
1999 Kitchen SG, Zack JA. Distribution of the human immunodeficiency virus coreceptors CXCR4 and CCR5 in fetal lymphoid organs: Implications for pathogenesis in utero Aids Research and Human Retroviruses. 15: 143-148. PMID 10029246 DOI: 10.1089/088922299311565  0.562
1998 Douek DC, McFarland RD, Keiser PH, Gage EA, Massey JM, Haynes BF, Polis MA, Haase AT, Feinberg MB, Sullivan JL, Jamieson BD, Zack JA, Picker LJ, Koup RA. Changes in thymic function with age and during the treatment of HIV infection Nature. 396: 690-695. PMID 9872319 DOI: 10.1038/25374  0.603
1998 Kitchen SG, Korin YD, Roth MD, Landay A, Zack JA. Costimulation of naive CD8+ lymphocytes induces CD4 expression and allows human immunodeficiency virus type 1 infection Journal of Virology. 72: 9054-9060. PMID 9765450 DOI: 10.1128/Jvi.72.11.9054-9060.1998  0.491
1998 Aldrovandi GM, Gao L, Bristol G, Zack JA. Regions of human immunodeficiency virus type 1 nef required for function in vivo. Journal of Virology. 72: 7032-9. PMID 9696795 DOI: 10.1128/Jvi.72.9.7032-7039.1998  0.44
1998 Jamieson BD, Zack JA. In vivo pathogenesis of a human immunodeficiency virus type 1 reporter virus. Journal of Virology. 72: 6520-6. PMID 9658095 DOI: 10.1128/Jvi.72.8.6520-6526.1998  0.622
1998 Koka PS, Fraser JK, Bryson Y, Bristol GC, Aldrovandi GM, Daar ES, Zack JA. Human immunodeficiency virus inhibits multilineage hematopoiesis in vivo. Journal of Virology. 72: 5121-7. PMID 9573283 DOI: 10.1128/Jvi.72.6.5121-5127.1998  0.64
1998 Korin YD, Zack JA. Progression to the G1b phase of the cell cycle is required for completion of human immunodeficiency virus type 1 reverse transcription in T cells. Journal of Virology. 72: 3161-8. PMID 9525642 DOI: 10.1128/Jvi.72.4.3161-3168.1998  0.639
1998 Gong J, Stenger S, Zack JA, Jones BE, Bristol GC, Modlin RL, Morrissey PJ, Barnes PF. Isolation of mycobacterium-reactive CD1-restricted T cells from patients with human immunodeficiency virus infection. The Journal of Clinical Investigation. 101: 383-9. PMID 9435310 DOI: 10.1172/Jci318  0.456
1997 Valentin A, Aldrovandi G, Zolotukhin AS, Cole SW, Zack JA, Pavlakis GN, Felber BK. Reduced viral load and lack of CD4 depletion in SCID-hu mice infected with Rev-independent clones of human immunodeficiency virus type Journal of Virology. 71: 9817-9822. PMID 9371653 DOI: 10.1128/Jvi.71.12.9817-9822.1997  0.585
1997 Jamieson BD, Uittenbogaart CH, Schmid I, Zack JA. High viral burden and rapid CD4+ cell depletion in human immunodeficiency virus type 1-infected SCID-hu mice suggest direct viral killing of thymocytes in vivo Journal of Virology. 71: 8245-8253. PMID 9343176 DOI: 10.1128/Jvi.71.11.8245-8253.1997  0.486
1997 Withers-Ward ES, Amado RG, Koka PS, Jamieson BD, Kaplan AH, Chen IS, Zack JA. Transient renewal of thymopoiesis in HIV-infected human thymic implants following antiviral therapy. Nature Medicine. 3: 1102-9. PMID 9334721 DOI: 10.1038/Nm1097-1102  0.61
1997 Kitchen SG, Zack JA. CXCR4 expression during lymphopoiesis: Implications for human immunodeficiency virus type 1 infection of the thymus Journal of Virology. 71: 6928-6934. PMID 9261420 DOI: 10.1128/Jvi.71.9.6928-6934.1997  0.611
1997 Bristol GC, Gao LY, Zack JA. Preparation and maintenance of SCID-hu mice for HIV research. Methods (San Diego, Calif.). 12: 343-7. PMID 9245615 DOI: 10.1006/Meth.1997.0488  0.565
1997 Kitchen SG, Uittenbogaart CH, Zack JA. Mechanism of human immunodeficiency virus type 1 localization in CD4- negative thymocytes: Differentiation from a CD4-positive precursor allows productive infection Journal of Virology. 71: 5713-5722. PMID 9223457 DOI: 10.1128/Jvi.71.8.5713-5722.1997  0.53
1997 Boldt-Houle DM, Jamieson BD, Aldrovandi GM, Rinaldo CR, Ehrlich GD, Zack JA. Loss of T cell receptor Vbeta repertoires in HIV type 1-infected SCID-hu mice. Aids Research and Human Retroviruses. 13: 125-34. PMID 9007198 DOI: 10.1089/Aid.1997.13.125  0.614
1997 An DS, Koyanagi Y, Zhao J-, Akkina R, Bristol G, Yamamoto N, Zack JA, Chen ISY. High-efficiency transduction of human lymphoid progenitor cells and expression in differentiated T cells. Journal of Virology. 71: 1397-1404. PMID 8995665 DOI: 10.1128/Jvi.71.2.1397-1404.1997  0.471
1997 Jamieson BD, Aldrovandi GM, Zack JA. The SCID-hu mouse: an in-vivo model for HIV-1 pathogenesis and stem cell gene therapy for AIDS. Seminars in Immunology. 8: 215-21. PMID 8883144 DOI: 10.1006/Smim.1996.0027  0.578
1996 Goncalves J, Korin Y, Zack J, Gabuzda D. Role of Vif in human immunodeficiency virus type 1 reverse transcription Journal of Virology. 70: 8701-8709. PMID 8970997 DOI: 10.1128/Jvi.70.12.8701-8709.1996  0.46
1996 Uittenbogaart CH, Anisman DJ, Jamieson BD, Kitchen S, Schmid I, Zack JA, Hays EF. Differential tropism of HIV-1 isolates for distinct thymocyte subsets in vitro Aids. 10. PMID 8805858 DOI: 10.1097/00002030-199606001-00001  0.565
1996 Feuer G, Fraser JK, Zack JA, Lee F, Feuer R, Chen ISY. Human T-cell leukemia virus infection of human hematopoietic progenitor cells: Maintenance of virus infection during differentiation in vitro and in vivo Journal of Virology. 70: 4038-4044. PMID 8648741 DOI: 10.1128/Jvi.70.6.4038-4044.1996  0.549
1996 Aldrovandi GM, Zack JA. Replication and pathogenicity of human immunodeficiency virus type 1 accessory gene mutants in SCID-hu mice. Journal of Virology. 70: 1505-11. PMID 8627668 DOI: 10.1128/Jvi.70.3.1505-1511.1996  0.549
1995 Daar ES, Chernyavskiy T, Zhao JQ, Krogstad P, Chen IS, Zack JA. Sequential determination of viral load and phenotype in human immunodeficiency virus type 1 infection. Aids Research and Human Retroviruses. 11: 3-9. PMID 7734193 DOI: 10.1089/Aid.1995.11.3  0.481
1995 Jamieson BD, Pang S, Aldrovandi GM, Zha J, Zack JA. In vivo pathogenic properties of two clonal human immunodeficiency virus type 1 isolates. Journal of Virology. 69: 6259-64. PMID 7666526 DOI: 10.1128/Jvi.69.10.6259-6264.1995  0.723
1995 Zack JA. The role of the cell cycle in HIV-1 infection. Advances in Experimental Medicine and Biology. 374: 27-31. PMID 7572398 DOI: 10.1007/978-1-4615-1995-9_3  0.64
1995 Koka P, He K, Zack JA, Kitchen S, Peacock W, Fried I, Tran T, Yashar SS, Merrill JE. Human immunodeficiency virus 1 envelope proteins induce interleukin 1, tumor necrosis factor alpha, and nitric oxide in glial cultures derived from fetal, neonatal, and adult human brain. The Journal of Experimental Medicine. 182: 941-51. PMID 7561697 DOI: 10.1084/Jem.182.4.941  0.528
1995 O'Brien W, Grovit-Ferbas K, Namazi A, Ovcak-Derzic S, Wang H, Park J, Yeramian C, Mao S, Zack J. Human immunodeficiency virus-type 1 replication can be increased in peripheral blood of seropositive patients after influenza vaccination Blood. 86: 1082-1089. DOI: 10.1182/blood.v86.3.1082.bloodjournal8631082  0.325
1995 O'Brien W, Grovit-Ferbas K, Namazi A, Ovcak-Derzic S, Wang H, Park J, Yeramian C, Mao S, Zack J. Human immunodeficiency virus-type 1 replication can be increased in peripheral blood of seropositive patients after influenza vaccination Blood. 86: 1082-1089. DOI: 10.1182/blood.V86.3.1082.1082  0.325
1994 Jamieson BD, Aldrovandi GM, Planelles V, Jowett JB, Gao L, Bloch LM, Chen IS, Zack JA. Requirement of human immunodeficiency virus type 1 nef for in vivo replication and pathogenicity. Journal of Virology. 68: 3478-85. PMID 8189487 DOI: 10.1128/Jvi.68.6.3478-3485.1994  0.573
1994 Akkina RK, Rosenblatt JD, Campbell AG, Chen ISY, Zack JA. Modeling human lymphoid precursor cell gene therapy in the SCID-hu mouse Blood. 84: 1393-1398. PMID 7520766 DOI: 10.1182/Blood.V84.5.1393.Bloodjournal8451393  0.483
1994 Krogstad PA, Zack JA, Chen IS. HIV-1 reverse transcription in cord blood lymphocytes: implications for infection of newborns. Aids Research and Human Retroviruses. 10: 143-7. PMID 7515257 DOI: 10.1089/Aid.1994.10.143  0.533
1994 O'Brien WA, Namazi A, Kalhor H, Mao SH, Zack JA, Chen ISY. Kinetics of human immunodeficiency virus type 1 reverse transcription in blood mononuclear phagocytes are slowed by limitations of nucleotide precursors Journal of Virology. 68: 1258-1263. PMID 7507180 DOI: 10.1128/jvi.68.2.1258-1263.1994  0.399
1994 Akkina R, Rosenblatt J, Campbell A, Chen I, Zack J. Modeling human lymphoid precursor cell gene therapy in the SCID-hu mouse Blood. 84: 1393-1398. DOI: 10.1182/blood.V84.5.1393.bloodjournal8451393  0.388
1994 Akkina R, Rosenblatt J, Campbell A, Chen I, Zack J. Modeling human lymphoid precursor cell gene therapy in the SCID-hu mouse Blood. 84: 1393-1398. DOI: 10.1182/blood.v84.5.1393.1393  0.388
1993 Aldrovandi GM, Feuer G, Gao L, Jamieson B, Kristeva M, Chen ISY, Zack JA. The SCID-hu mouse as a model for HIV-1 infection Nature. 363: 732-736. PMID 8515816 DOI: 10.1038/363732A0  0.603
1993 Kaplan AH, Zack JA, Knigge M, Paul DA, Kempf DJ, Norbeck DW, Swanstrom R. Partial inhibition of the human immunodeficiency virus type 1 protease results in aberrant virus assembly and the formation of noninfectious particles Journal of Virology. 67: 4050-4055. PMID 8510215 DOI: 10.1128/Jvi.67.7.4050-4055.1993  0.392
1993 Feuer G, Zack J, Harrington WJ, Valderama R, Rosenblatt J, Wachsman W, Baird S, Chen I. Establishment of human T-cell leukemia virus type I T-cell lymphomas in severe combined immunodeficient mice Blood. 82: 722-731. DOI: 10.1182/Blood.V82.3.722.Bloodjournal823722  0.505
1993 Sevall JS, Prince H, Garratty G, O'Brien WA, Zack JA. Rapid enzymatic analysis for human immunodeficiency virus type 1 DNA in clinical specimens Clinical Chemistry. 39: 433-439. DOI: 10.1093/clinchem/39.3.433  0.307
1992 Cann AJ, Churcher MJ, Boyd M, O'brien W, Zhao J, Zack J, Chen ISY. The region of the envelope gene of human immunodeficiency virus type 1 responsible for determination of cell tropism. Journal of Virology. 66: 305-309. PMID 1727490 DOI: 10.1128/Jvi.66.1.305-309.1992  0.553
1992 Hays EF, Uittenbogaart CH, Brewer JC, Vollger LW, Zack JA. In vitro studies of HIV-1 expression in thymocytes from infants and children Aids. 6: 265-272. PMID 1567573 DOI: 10.1097/00002030-199203000-00003  0.511
1992 Merrill JE, Koyanagi Y, Zack J, Thomas L, Martin F, Chen ISY. Induction of interleukin-1 and tumor necrosis factor alpha in brain cultures by human immunodeficiency virus type 1 Journal of Virology. 66: 2217-2225. PMID 1548758 DOI: 10.1128/Jvi.66.4.2217-2225.1992  0.399
1992 Clerici M, Giorgi JV, Chou CC, Gudeman VK, Zack JA, Gupta P, Ho HN, Nishanian PG, Berzofsky JA, Shearer GM. Cell-mediated immune response to human immunodeficiency virus (HIV) type 1 in seronegative homosexual men with recent sexual exposure to HIV-1. The Journal of Infectious Diseases. 165: 1012-9. PMID 1533867 DOI: 10.1093/Infdis/165.6.1012  0.559
1992 Zack JA, Haislip AM, Krogstad P, Chen IS. Incompletely reverse-transcribed human immunodeficiency virus type 1 genomes in quiescent cells can function as intermediates in the retroviral life cycle. Journal of Virology. 66: 1717-25. PMID 1371173 DOI: 10.1128/Jvi.66.3.1717-1725.1992  0.61
1992 Rich EA, Chen IS, Zack JA, Leonard ML, O'Brien WA. Increased susceptibility of differentiated mononuclear phagocytes to productive infection with human immunodeficiency virus-1 (HIV-1). The Journal of Clinical Investigation. 89: 176-83. PMID 1370293 DOI: 10.1172/JCI115559  0.47
1990 Cann AJ, Zack JA, Go AS, Arrigo SJ, Koyanagi Y, Green PL, Koyanagi Y, Pang S, Chen IS. Human immunodeficiency virus type 1 T-cell tropism is determined by events prior to provirus formation. Journal of Virology. 64: 4735-42. PMID 2398528 DOI: 10.1128/Jvi.64.10.4735-4742.1990  0.645
1990 Arrigo SJ, Weitsman S, Zack JA, Chen IS. Characterization and expression of novel singly spliced RNA species of human immunodeficiency virus type 1. Journal of Virology. 64: 4585-8. PMID 2384924 DOI: 10.1128/Jvi.64.9.4585-4588.1990  0.437
1990 Zack JA, Arrigo SJ, Weitsman SR, Go AS, Haislip A, Chen IS. HIV-1 entry into quiescent primary lymphocytes: molecular analysis reveals a labile, latent viral structure. Cell. 61: 213-22. PMID 2331748 DOI: 10.1016/0092-8674(90)90802-L  0.636
1990 O'Brien WA, Koyanagi Y, Namazie A, Zhao JQ, Diagne A, Idler K, Zack JA, Chen IS. HIV-1 tropism for mononuclear phagocytes can be determined by regions of gp120 outside the CD4-binding domain. Nature. 348: 69-73. PMID 2172833 DOI: 10.1038/348069A0  0.556
1990 Zack JA, Arrigo SJ, Chen IS. Control of expression and cell tropism of human immunodeficiency virus type 1. Advances in Virus Research. 38: 125-46. PMID 1977292 DOI: 10.1016/S0065-3527(08)60861-1  0.605
1990 O??Brien WA, Zack JA, Chen ISY. Molecular pathogenesis of HIV-1 Aids. 4: S49. DOI: 10.1097/00002030-199001001-00009  0.386
1989 Lee H, Swanson P, Shorty VS, Zack JA, Rosenblatt JD, Chen IS. High rate of HTLV-II infection in seropositive i.v. drug abusers in New Orleans. Science (New York, N.Y.). 244: 471-5. PMID 2655084 DOI: 10.1126/Science.2655084  0.397
1988 Zack JA, Cann AJ, Lugo JP, Chen IS. HIV-1 production from infected peripheral blood T cells after HTLV-I induced mitogenic stimulation. Science (New York, N.Y.). 240: 1026-9. PMID 2835813 DOI: 10.1126/Science.2835813  0.639
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