Year |
Citation |
Score |
2017 |
Lehmann J, Cheng TY, Aggarwal A, Park AS, Zeiler E, Raju RM, Akopian T, Kandror O, Bach NC, Sacchettini JC, Moody DB, Rubin EJ, Sieber SA. An antibacterial β-lactone kills Mycobacterium tuberculosis by infiltrating mycolic acid biosynthesis. Angewandte Chemie (International Ed. in English). PMID 29067779 DOI: 10.1002/Anie.201709365 |
0.446 |
|
2016 |
Marakalala MJ, Raju RM, Sharma K, Zhang YJ, Eugenin EA, Prideaux B, Daudelin IB, Chen PY, Booty MG, Kim JH, Eum SY, Via LE, Behar SM, Barry CE, Mann M, et al. Inflammatory signaling in human tuberculosis granulomas is spatially organized. Nature Medicine. PMID 27043495 DOI: 10.1038/Nm.4073 |
0.477 |
|
2016 |
Raju RM, Raju SM, Zhao Y, Rubin EJ. Leveraging Advances in Tuberculosis Diagnosis and Treatment to Address Nontuberculous Mycobacterial Disease. Emerging Infectious Diseases. 22: 365-9. PMID 26886068 DOI: 10.3201/Eid2203.151643 |
0.438 |
|
2015 |
Moreira W, Ngan GJ, Low JL, Poulsen A, Chia BC, Ang MJ, Yap A, Fulwood J, Lakshmanan U, Lim J, Khoo AY, Flotow H, Hill J, Raju RM, Rubin EJ, et al. Target mechanism-based whole-cell screening identifies bortezomib as an inhibitor of caseinolytic protease in mycobacteria. Mbio. 6: e00253-15. PMID 25944857 DOI: 10.1128/Mbio.00253-15 |
0.407 |
|
2014 |
Raju RM, Jedrychowski MP, Wei JR, Pinkham JT, Park AS, O'Brien K, Rehren G, Schnappinger D, Gygi SP, Rubin EJ. Post-translational regulation via Clp protease is critical for survival of Mycobacterium tuberculosis. Plos Pathogens. 10: e1003994. PMID 24603869 DOI: 10.1371/Journal.Ppat.1003994 |
0.43 |
|
2012 |
Raju RM, Goldberg AL, Rubin EJ. Bacterial proteolytic complexes as therapeutic targets. Nature Reviews. Drug Discovery. 11: 777-89. PMID 23023677 DOI: 10.1038/Nrd3846 |
0.411 |
|
2012 |
Raju RM, Unnikrishnan M, Rubin DH, Krishnamoorthy V, Kandror O, Akopian TN, Goldberg AL, Rubin EJ. Mycobacterium tuberculosis ClpP1 and ClpP2 function together in protein degradation and are required for viability in vitro and during infection. Plos Pathogens. 8: e1002511. PMID 22359499 DOI: 10.1371/Journal.Ppat.1002511 |
0.463 |
|
2012 |
Akopian T, Kandror O, Raju RM, Unnikrishnan M, Rubin EJ, Goldberg AL. The active ClpP protease from M. tuberculosis is a complex composed of a heptameric ClpP1 and a ClpP2 ring. The Embo Journal. 31: 1529-41. PMID 22286948 DOI: 10.1038/Emboj.2012.5 |
0.415 |
|
2012 |
La Rosa V, Poce G, Canseco JO, Buroni S, Pasca MR, Biava M, Raju RM, Porretta GC, Alfonso S, Battilocchio C, Javid B, Sorrentino F, Ioerger TR, Sacchettini JC, Manetti F, et al. MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212. Antimicrobial Agents and Chemotherapy. 56: 324-31. PMID 22024828 DOI: 10.1128/Aac.05270-11 |
0.443 |
|
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