Sebastien Lemieux, Ph.D. - Publications

Affiliations: 
2002 Université de Montréal, Montréal, Canada 
Area:
Computer Science

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Larouche JD, Trofimov A, Hesnard L, Ehx G, Zhao Q, Vincent K, Durette C, Gendron P, Laverdure JP, Bonneil É, Côté C, Lemieux S, Thibault P, Perreault C. Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues. Genome Medicine. 12: 40. PMID 32345368 DOI: 10.1186/s13073-020-00740-7  0.68
2020 Zhao Q, Laverdure JP, Lanoix J, Durette C, Coté C, Bonneil E, Laumont CM, Gendron P, Vincent K, Courcelles M, Lemieux S, Millar DG, Ohashi PS, Thibault P, Perreault C. Proteogenomics uncovers a vast repertoire of shared tumor-specific antigens in ovarian cancer. Cancer Immunology Research. PMID 32047025 DOI: 10.1158/2326-6066.CIR-19-0541  0.68
2019 Audemard EO, Gendron P, Feghaly A, Lavallée VP, Hébert J, Sauvageau G, Lemieux S. Targeted variant detection using unaligned RNA-Seq reads. Life Science Alliance. 2. PMID 31427380 DOI: 10.26508/lsa.201900336  0.68
2019 Garg S, Reyes-Palomares A, He L, Bergeron A, Lavallée VP, Lemieux S, Gendron P, Rohde C, Xia J, Jagdhane P, Müller-Tidow C, Lipka DB, Imren S, Humphries RK, Waskow C, et al. Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML. Blood. PMID 31076446 DOI: 10.1182/blood.2018862383  0.68
2018 Laumont CM, Vincent K, Hesnard L, Audemard É, Bonneil É, Laverdure JP, Gendron P, Courcelles M, Hardy MP, Côté C, Durette C, St-Pierre C, Benhammadi M, Lanoix J, Vobecky S, ... ... Lemieux S, et al. Noncoding regions are the main source of targetable tumor-specific antigens. Science Translational Medicine. 10. PMID 30518613 DOI: 10.1126/scitranslmed.aau5516  0.68
2016 Lavallée VP, Krosl J, Lemieux S, Boucher G, Gendron P, Pabst C, Boivin I, Marinier A, Guidos CJ, Meloche S, Hébert J, Sauvageau G. Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors. Blood. PMID 27034432 DOI: 10.1182/blood-2016-03-705053  0.68
2016 Lavallée VP, Lemieux S, Boucher G, Gendron P, Boivin I, Armstrong RN, Sauvageau G, Hébert J. RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature. Blood. PMID 26968532 DOI: 10.1182/blood-2016-03-703868  0.68
2016 Pabst C, Bergeron A, Lavallée VP, Yeh J, Gendron P, Norddahl GL, Krosl J, Boivin I, Deneault E, Simard J, Imren S, Boucher G, Eppert K, Herold T, Bohlander SK, ... ... Lemieux S, et al. GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo. Blood. PMID 26834243 DOI: 10.1182/blood-2015-11-683649  0.68
2016 Laumont CM, Daouda T, Laverdure JP, Bonneil É, Caron-Lizotte O, Hardy MP, Granados DP, Durette C, Lemieux S, Thibault P, Perreault C. Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames. Nature Communications. 7: 10238. PMID 26728094 DOI: 10.1038/ncomms10238  1
2015 Lavallée VP, Baccelli I, Krosl J, Wilhelm B, Barabé F, Gendron P, Boucher G, Lemieux S, Marinier A, Meloche S, Hébert J, Sauvageau G. The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias. Nature Genetics. 47: 1030-7. PMID 26237430 DOI: 10.1038/ng.3371  1
2015 Bonneau E, Girard N, Lemieux S, Legault P. The NMR structure of the II-III-VI three-way junction from the Neurospora VS ribozyme reveals a critical tertiary interaction and provides new insights into the global ribozyme structure. Rna (New York, N.Y.). 21: 1621-32. PMID 26124200 DOI: 10.1261/rna.052076.115  1
2015 St-Pierre C, Trofimov A, Brochu S, Lemieux S, Perreault C. Differential Features of AIRE-Induced and AIRE-Independent Promiscuous Gene Expression in Thymic Epithelial Cells. Journal of Immunology (Baltimore, Md. : 1950). 195: 498-506. PMID 26034170 DOI: 10.4049/jimmunol.1500558  1
2015 Lavallée VP, Gendron P, Lemieux S, D'Angelo G, Hébert J, Sauvageau G. EVI1-rearranged acute myeloid leukemias are characterized by distinct molecular alterations. Blood. 125: 140-3. PMID 25331116 DOI: 10.1182/blood-2014-07-591529  1
2014 Gerby B, Tremblay CS, Tremblay M, Rojas-Sutterlin S, Herblot S, Hébert J, Sauvageau G, Lemieux S, Lécuyer E, Veiga DF, Hoang T. SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells. Plos Genetics. 10: e1004768. PMID 25522233 DOI: 10.1371/journal.pgen.1004768  1
2014 Granados DP, Sriranganadane D, Daouda T, Zieger A, Laumont CM, Caron-Lizotte O, Boucher G, Hardy MP, Gendron P, Côté C, Lemieux S, Thibault P, Perreault C. Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides. Nature Communications. 5: 3600. PMID 24714562 DOI: 10.1038/ncomms4600  1
2014 Ashton-Beaucage D, Udell CM, Gendron P, Sahmi M, Lefrançois M, Baril C, Guenier AS, Duchaine J, Lamarre D, Lemieux S, Therrien M. A functional screen reveals an extensive layer of transcriptional and splicing control underlying RAS/MAPK signaling in Drosophila. Plos Biology. 12: e1001809. PMID 24643257 DOI: 10.1371/journal.pbio.1001809  1
2014 Pabst C, Krosl J, Fares I, Boucher G, Ruel R, Marinier A, Lemieux S, Hébert J, Sauvageau G. Identification of small molecules that support human leukemia stem cell activity ex vivo. Nature Methods. 11: 436-42. PMID 24562423 DOI: 10.1038/nmeth.2847  1
2013 Macrae T, Sargeant T, Lemieux S, Hébert J, Deneault E, Sauvageau G. RNA-Seq reveals spliceosome and proteasome genes as most consistent transcripts in human cancer cells. Plos One. 8: e72884. PMID 24069164 DOI: 10.1371/journal.pone.0072884  1
2013 Nocq J, Celton M, Gendron P, Lemieux S, Wilhelm BT. Harnessing virtual machines to simplify next-generation DNA sequencing analysis. Bioinformatics (Oxford, England). 29: 2075-83. PMID 23786767 DOI: 10.1093/bioinformatics/btt352  1
2013 Courcelles M, Frémin C, Voisin L, Lemieux S, Meloche S, Thibault P. Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions. Molecular Systems Biology. 9: 669. PMID 23712012 DOI: 10.1038/msb.2013.25  1
2013 St-Pierre C, Brochu S, Vanegas JR, Dumont-Lagacé M, Lemieux S, Perreault C. Transcriptome sequencing of neonatal thymic epithelial cells. Scientific Reports. 3: 1860. PMID 23681267 DOI: 10.1038/srep01860  1
2013 Serhal P, Lemieux S. Correction of spatial bias in oligonucleotide array data. Advances in Bioinformatics. 2013: 167915. PMID 23573083 DOI: 10.1155/2013/167915  1
2012 Courcelles M, Bridon G, Lemieux S, Thibault P. Occurrence and detection of phosphopeptide isomers in large-scale phosphoproteomics experiments. Journal of Proteome Research. 11: 3753-65. PMID 22668510 DOI: 10.1021/pr300229m  1
2012 Granados DP, Yahyaoui W, Laumont CM, Daouda T, Muratore-Schroeder TL, Côté C, Laverdure JP, Lemieux S, Thibault P, Perreault C. MHC I-associated peptides preferentially derive from transcripts bearing miRNA response elements. Blood. 119: e181-91. PMID 22438248 DOI: 10.1182/blood-2012-02-412593  1
2012 Simon C, Chagraoui J, Krosl J, Gendron P, Wilhelm B, Lemieux S, Boucher G, Chagnon P, Drouin S, Lambert R, Rondeau C, Bilodeau A, Lavallée S, Sauvageau M, Hébert J, et al. A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia. Genes & Development. 26: 651-6. PMID 22431509 DOI: 10.1101/gad.186411.111  1
2012 Lacroix-Labonté J, Girard N, Lemieux S, Legault P. Helix-length compensation studies reveal the adaptability of the VS ribozyme architecture. Nucleic Acids Research. 40: 2284-93. PMID 22086962 DOI: 10.1093/nar/gkr1018  1
2011 Caron E, Vincent K, Fortier MH, Laverdure JP, Bramoullé A, Hardy MP, Voisin G, Roux PP, Lemieux S, Thibault P, Perreault C. The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation. Molecular Systems Biology. 7: 533. PMID 21952136 DOI: 10.1038/msb.2011.68  1
2011 Courcelles M, Lemieux S, Voisin L, Meloche S, Thibault P. ProteoConnections: a bioinformatics platform to facilitate proteome and phosphoproteome analyses. Proteomics. 11: 2654-71. PMID 21630457 DOI: 10.1002/pmic.201000776  1
2010 Caron E, Ghosh S, Matsuoka Y, Ashton-Beaucage D, Therrien M, Lemieux S, Perreault C, Roux PP, Kitano H. A comprehensive map of the mTOR signaling network. Molecular Systems Biology. 6: 453. PMID 21179025 DOI: 10.1038/msb.2010.108  1
2010 de Verteuil D, Muratore-Schroeder TL, Granados DP, Fortier MH, Hardy MP, Bramoullé A, Caron E, Vincent K, Mader S, Lemieux S, Thibault P, Perreault C. Deletion of immunoproteasome subunits imprints on the transcriptome and has a broad impact on peptides presented by major histocompatibility complex I molecules. Molecular & Cellular Proteomics : McP. 9: 2034-47. PMID 20484733 DOI: 10.1074/mcp.M900566-MCP200  1
2009 Trunk K, Gendron P, Nantel A, Lemieux S, Roemer T, Raymond M. Depletion of the cullin Cdc53p induces morphogenetic changes in Candida albicans. Eukaryotic Cell. 8: 756-67. PMID 19270112 DOI: 10.1128/EC.00332-08  1
2009 Devkota B, Petrov AS, Lemieux S, Boz MB, Tang L, Schneemann A, Johnson JE, Harvey SC. Structural and electrostatic characterization of pariacoto virus: implications for viral assembly. Biopolymers. 91: 530-8. PMID 19226622 DOI: 10.1002/bip.21168  1
2009 Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P. The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 30: 143-54. PMID 19144319 DOI: 10.1016/j.immuni.2008.11.006  1
2008 Fedorova ND, Khaldi N, Joardar VS, Maiti R, Amedeo P, Anderson MJ, Crabtree J, Silva JC, Badger JH, Albarraq A, Angiuoli S, Bussey H, Bowyer P, Cotty PJ, Dyer PS, ... ... Lemieux S, et al. Genomic islands in the pathogenic filamentous fungus Aspergillus fumigatus. Plos Genetics. 4: e1000046. PMID 18404212 DOI: 10.1371/journal.pgen.1000046  1
2008 Bouchard P, Lacroix-Labonté J, Desjardins G, Lampron P, Lisi V, Lemieux S, Major F, Legault P. Role of SLV in SLI substrate recognition by the Neurospora VS ribozyme. Rna (New York, N.Y.). 14: 736-48. PMID 18314503 DOI: 10.1261/rna.824308  1
2008 Fortier MH, Caron E, Hardy MP, Voisin G, Lemieux S, Perreault C, Thibault P. The MHC class I peptide repertoire is molded by the transcriptome. The Journal of Experimental Medicine. 205: 595-610. PMID 18299400 DOI: 10.1084/jem.20071985  1
2008 Sauvageau M, Miller M, Lemieux S, Lessard J, Hébert J, Sauvageau G. Quantitative expression profiling guided by common retroviral insertion sites reveals novel and cell type specific cancer genes in leukemia. Blood. 111: 790-9. PMID 17906077 DOI: 10.1182/blood-2007-07-098236  1
2007 Héroux M, Hogue M, Lemieux S, Bouvier M. Functional calcitonin gene-related peptide receptors are formed by the asymmetric assembly of a calcitonin receptor-like receptor homo-oligomer and a monomer of receptor activity-modifying protein-1. The Journal of Biological Chemistry. 282: 31610-20. PMID 17785463 DOI: 10.1074/jbc.M701790200  1
2007 Xu D, Jiang B, Ketela T, Lemieux S, Veillette K, Martel N, Davison J, Sillaots S, Trosok S, Bachewich C, Bussey H, Youngman P, Roemer T. Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans. Plos Pathogens. 3: e92. PMID 17604452 DOI: 10.1371/journal.ppat.0030092  1
2006 Lemieux S. Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression. Bmc Bioinformatics. 7: 391. PMID 16934150 DOI: 10.1186/1471-2105-7-391  1
2006 Lemieux S, Major F. Automated extraction and classification of RNA tertiary structure cyclic motifs. Nucleic Acids Research. 34: 2340-6. PMID 16679452 DOI: 10.1093/nar/gkl120  1
2003 Roemer T, Jiang B, Davison J, Ketela T, Veillette K, Breton A, Tandia F, Linteau A, Sillaots S, Marta C, Martel N, Veronneau S, Lemieux S, Kauffman S, Becker J, et al. Large-scale essential gene identification in Candida albicans and applications to antifungal drug discovery. Molecular Microbiology. 50: 167-81. PMID 14507372 DOI: 10.1046/j.1365-2958.2003.03697.x  1
2002 Lemieux S, Major F. RNA canonical and non-canonical base pairing types: a recognition method and complete repertoire. Nucleic Acids Research. 30: 4250-63. PMID 12364604  1
2001 Gendron P, Lemieux S, Major F. Quantitative analysis of nucleic acid three-dimensional structures. Journal of Molecular Biology. 308: 919-36. PMID 11352582 DOI: 10.1006/jmbi.2001.4626  1
1998 Zhang F, Lemieux S, Wu X, St-Arnaud D, McMurray CT, Major F, Anderson D. Function of hexameric RNA in packaging of bacteriophage phi 29 DNA in vitro. Molecular Cell. 2: 141-7. PMID 9702201  1
1998 Lemieux S, Chartrand P, Cedergren R, Major F. Modeling active RNA structures using the intersection of conformational space: application to the lead-activated ribozyme. Rna (New York, N.Y.). 4: 739-49. PMID 9671048 DOI: 10.1017/S1355838298971266  1
1998 Major F, Lemieux S, Ftouhi A. Computer RNA Three-Dimensional Modeling from Low-Resolution Data and Multiple-Sequence Information Acs Symposium Series. 682: 394-404.  1
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