Valentino J. Stella - Publications

Affiliations: 
Pharmaceutical Chemistry University of Kansas, Lawrence, KS, United States 
Area:
Pharmaceutical Chemistry

151 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lopalco A, Lopedota AA, Laquintana V, Denora N, Stella VJ. Boric Acid, a Lewis Acid with Unique and Unusual Properties: Formulation Implications. Journal of Pharmaceutical Sciences. PMID 32353453 DOI: 10.1016/J.Xphs.2020.04.015  0.379
2019 Lopalco A, Deeken R, Douglas J, Denora N, Stella VJ. Some Preformulation Studies of Pyruvic Acid and Other α-Keto Carboxylic Acids in Aqueous Solution: Pharmaceutical Formulation Implications for These Peroxide Scavengers. Journal of Pharmaceutical Sciences. PMID 31163186 DOI: 10.1016/J.Xphs.2019.05.030  0.397
2018 Lopalco A, Stella VJ, Thompson WH. Origins, and formulation implications, of the pK difference between boronic acids and their esters: A density functional theory study. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 30118849 DOI: 10.1016/J.Ejps.2018.08.017  0.408
2016 Phizackerley KM, Jumaa M, Lopalco A, Wolfe BH, Ablan CD, Stella VJ. Mechanism of Degradation of an α-Keto-Epoxide, a Model for the Warhead for Various Proteasome Inhibitor Anticancer Agents. Journal of Pharmaceutical Sciences. PMID 28007565 DOI: 10.1016/J.Xphs.2016.12.006  0.318
2016 Lopalco A, Marinaro WA, Day VW, Stella VJ. Isolation, Solubility, and Characterization of D-Mannitol Esters of 4-Methoxybenzeneboronic Acid. Journal of Pharmaceutical Sciences. PMID 27938893 DOI: 10.1016/J.Xphs.2016.10.022  0.79
2016 Lopalco A, Stella VJ. Effect of Molecular Structure on the Relative Hydrogen Peroxide Scavenging Ability of Some α-Keto Carboxylic Acids. Journal of Pharmaceutical Sciences. PMID 27209460 DOI: 10.1016/J.Xphs.2016.03.041  0.399
2015 Lopalco A, Dalwadi G, Niu S, Schowen RL, Douglas J, Stella VJ. Mechanism of Decarboxylation of Pyruvic Acid in the Presence of Hydrogen Peroxide. Journal of Pharmaceutical Sciences. PMID 26422524 DOI: 10.1002/Jps.24653  0.364
2015 Lopalco A, Douglas J, Denora N, Stella VJ. Determination of pKa and Hydration Constants for a Series of α-Keto-Carboxylic Acids Using Nuclear Magnetic Resonance Spectrometry. Journal of Pharmaceutical Sciences. PMID 26149194 DOI: 10.1002/Jps.24539  0.372
2015 Marinaro WA, Prankerd R, Kinnari K, Stella VJ. Interaction of model aryl- and alkyl-boronic acids and 1,2-diols in aqueous solution. Journal of Pharmaceutical Sciences. 104: 1399-408. PMID 25600471 DOI: 10.1002/Jps.24346  0.785
2014 Han S, Quach T, Hu L, Wahab A, Charman WN, Stella VJ, Trevaskis NL, Simpson JS, Porter CJ. Targeted delivery of a model immunomodulator to the lymphatic system: comparison of alkyl ester versus triglyceride mimetic lipid prodrug strategies. Journal of Controlled Release : Official Journal of the Controlled Release Society. 177: 1-10. PMID 24398334 DOI: 10.1016/J.Jconrel.2013.12.031  0.375
2013 Willcockson MG, Toteva MM, Stella VJ. Hydrolysis of the quinone methide of butylated hydroxytoluene in aqueous solutions. Journal of Pharmaceutical Sciences. 102: 3579-85. PMID 23873381 DOI: 10.1002/Jps.23657  0.439
2013 Stella VJ. Chemical drug stability in lipids, modified lipids, and polyethylene oxide-containing formulations. Pharmaceutical Research. 30: 3018-28. PMID 23636838 DOI: 10.1007/S11095-013-1051-2  0.383
2012 Neervannan S, Southard MZ, Stella VJ. Dissolution of weak acids under laminar flow and rotating disk hydrodynamic conditions: application of a comprehensive convection-diffusion-migration-reaction transport model. Journal of Pharmaceutical Sciences. 101: 3180-9. PMID 22623113 DOI: 10.1002/Jps.23209  0.364
2012 Marinaro WA, Schieber LJ, Munson EJ, Day VW, Stella VJ. Properties of a model aryl boronic acid and its boroxine. Journal of Pharmaceutical Sciences. 101: 3190-8. PMID 22614918 DOI: 10.1002/Jps.23207  0.791
2012 Nti-Addae KW, Guarino VR, Dalwadi G, Stella VJ. Determination of the permeability characteristics of two sulfenamide prodrugs of linezolid across Caco-2 cells. Journal of Pharmaceutical Sciences. 101: 3134-41. PMID 22374830 DOI: 10.1002/Jps.23084  0.749
2012 Gangwar S, Pauletti GM, Siahaan TJ, Stella VJ, Borchardt RT. Synthesis of an esterase-sensitive cyclic prodrug of a model hexapeptide having enhanced membrane permeability and enzymatic stability using an acyloxyalkoxy promoiety. Methods in Molecular Medicine. 23: 37-51. PMID 21380890 DOI: 10.1385/0-89603-517-4:37  0.344
2011 Rao VM, Zannou EA, Stella VJ. Design of tablets for the delayed and complete release of poorly water-soluble weak base drugs using SBE7M-β-CD as a solubilizing agent. Journal of Pharmaceutical Sciences. 100: 1576-87. PMID 24081477 DOI: 10.1002/Jps.22375  0.797
2011 Nti-Addae KW, Laurence JS, Skinner AL, Stella VJ. Reversion of sulfenamide prodrugs in the presence of free thiol-containing proteins Journal of Pharmaceutical Sciences. 100: 3023-3027. PMID 21547913 DOI: 10.1002/Jps.22505  0.79
2011 Guarino VR, Nti-Addae K, Stella VJ. Reprint of "MDCK cell permeability characteristics of a sulfenamide produg: strategic implications in considering sulfenamide prodrugs for oral delivery of NH acids" [Bioorg. Med. Chem. Lett. 21 (2011) 172-175]. Bioorganic & Medicinal Chemistry Letters. 21: 2780-3. PMID 21513867 DOI: 10.1016/S0960-894X(11)00473-2  0.79
2011 Guarino VR, Nti-Addae K, Stella VJ. MDCK cell permeability characteristics of a sulfenamide prodrug: strategic implications in considering sulfenamide prodrugs for oral delivery of NH-acids. Bioorganic & Medicinal Chemistry Letters. 21: 172-5. PMID 21126873 DOI: 10.1016/J.Bmcl.2010.11.043  0.79
2011 Nti-Addae KW, Stella VJ. In vitro conversion of model sulfenamide prodrugs in the presence of small molecule thiols. Journal of Pharmaceutical Sciences. 100: 1001-8. PMID 20957747 DOI: 10.1002/Jps.22347  0.804
2011 Stella VJ, Rao VM, Zannou EA, Zia V. Erratum to “Mechanisms of drug release from cyclodextrin complexes” [Advanced Drug Delivery Reviews 36 (1999) 3–16] Advanced Drug Delivery Reviews. 63: 1371. DOI: 10.1016/J.Addr.2011.06.006  0.784
2010 Hemenway JN, Stella VJ. In vitro and in vivo evaluation of a novel water-soluble N-glycyl prodrug (N-GLY-CBZ) of carbamazepine. Journal of Pharmaceutical Sciences. 99: 4565-75. PMID 20845455 DOI: 10.1002/Jps.22171  0.768
2010 Stella VJ. Prodrugs: Some thoughts and current issues. Journal of Pharmaceutical Sciences. 99: 4755-65. PMID 20821387 DOI: 10.1002/Jps.22205  0.361
2010 Dhareshwar SS, Stella VJ. A novel prodrug strategy for beta-dicarbonyl carbon acids: syntheses and evaluation of the physicochemical characteristics of C-phosphoryloxymethyl (POM) and phosphoryloxymethyloxymethyl (POMOM) prodrug derivatives. Journal of Pharmaceutical Sciences. 99: 2711-23. PMID 20020525 DOI: 10.1002/Jps.22021  0.784
2010 Hemenway JN, Jarho P, Henri JT, Nair SK, VanderVelde D, Georg GI, Stella VJ. Preparation and physicochemical characterization of a novel water-soluble prodrug of carbamazepine. Journal of Pharmaceutical Sciences. 99: 1810-25. PMID 19774656 DOI: 10.1002/Jps.21952  0.79
2010 Tian J, Stella VJ. Degradation of paclitaxel and related compounds in aqueous solutions III: Degradation under acidic pH conditions and overall kinetics. Journal of Pharmaceutical Sciences. 99: 1288-98. PMID 19743504 DOI: 10.1002/Jps.21910  0.617
2009 Tongiani S, Ozeki T, Stella VJ. Sulfobutyl ether-alkyl ether mixed cyclodextrin derivatives with enhanced inclusion ability. Journal of Pharmaceutical Sciences. 98: 4769-80. PMID 19408308 DOI: 10.1002/Jps.21791  0.305
2009 Sotthivirat S, Haslam JL, Lee PI, Rao VM, Stella VJ. Release mechanisms of a sparingly water-soluble drug from controlled porosity-osmotic pump pellets using sulfobutylether-beta-cyclodextrin as both a solubilizing and osmotic agent. Journal of Pharmaceutical Sciences. 98: 1992-2000. PMID 18823032 DOI: 10.1002/Jps.21567  0.805
2009 Dhareshwar SS, Stella VJ. Breakdown kinetics of C-hydroxymethyl beta-dicarbonyl derivatives of carbon acids: implications in the bioconversion rate of C-phosphoryloxymethyl prodrugs of carbon acids. Journal of Pharmaceutical Sciences. 98: 1804-12. PMID 18781645 DOI: 10.1002/Jps.21540  0.762
2008 Dhareshwar SS, Stella VJ. Your prodrug releases formaldehyde: should you be concerned? No! Journal of Pharmaceutical Sciences. 97: 4184-93. PMID 18288723 DOI: 10.1002/Jps.21319  0.766
2008 Tian J, Stella VJ. Degradation of paclitaxel and related compounds in aqueous solutions II: Nonepimerization degradation under neutral to basic pH conditions. Journal of Pharmaceutical Sciences. 97: 3100-8. PMID 17963215 DOI: 10.1002/Jps.21214  0.609
2008 Tian J, Stella VJ. Degradation of paclitaxel and related compounds in aqueous solutions I: epimerization. Journal of Pharmaceutical Sciences. 97: 1224-35. PMID 17680660 DOI: 10.1002/Jps.21112  0.62
2007 Hemenway JN, Nti-Addae K, Guarino VR, Stella VJ. Preparation, characterization and in vivo conversion of new water-soluble sulfenamide prodrugs of carbamazepine. Bioorganic & Medicinal Chemistry Letters. 17: 6629-32. PMID 17928225 DOI: 10.1016/J.Bmcl.2007.09.045  0.758
2007 Stella VJ, Nti-Addae KW. Prodrug strategies to overcome poor water solubility. Advanced Drug Delivery Reviews. 59: 677-94. PMID 17628203 DOI: 10.1016/J.Addr.2007.05.013  0.794
2007 Guarino VR, Karunaratne V, Stella VJ. Sulfenamides as prodrugs of NH-acidic compounds: a new prodrug option for the amide bond. Bioorganic & Medicinal Chemistry Letters. 17: 4910-3. PMID 17604170 DOI: 10.1016/J.Bmcl.2007.06.037  0.777
2007 Denora N, Potts BC, Stella VJ. A mechanistic and kinetic study of the beta-lactone hydrolysis of Salinosporamide A (NPI-0052), a novel proteasome inhibitor. Journal of Pharmaceutical Sciences. 96: 2037-47. PMID 17554770 DOI: 10.1002/Jps.20835  0.403
2007 Sotthivirat S, Haslam JL, Stella VJ. Controlled porosity-osmotic pump pellets of a poorly water-soluble drug using sulfobutylether-beta-cyclodextrin, (SBE) 7M-beta-CD, as a solubilizing and osmotic agent. Journal of Pharmaceutical Sciences. 96: 2364-74. PMID 17497739 DOI: 10.1002/Jps.20891  0.745
2007 Sotthivirat S, Lubach JW, Haslam JL, Munson EJ, Stella VJ. Characterization of prednisolone in controlled porosity osmotic pump pellets using solid-state NMR spectroscopy. Journal of Pharmaceutical Sciences. 96: 1008-17. PMID 17455361 DOI: 10.1002/Jps.20798  0.74
2007 Sotthivirat S, Haslam JL, Stella VJ. Evaluation of various properties of alternative salt forms of sulfobutylether-beta-cyclodextrin, (SBE)7M-beta-CD. International Journal of Pharmaceutics. 330: 73-81. PMID 17045435 DOI: 10.1016/J.Ijpharm.2006.08.046  0.742
2005 Tongiani S, Velde DV, Ozeki T, Stella VJ. Sulfoalkyl ether-alkyl ether cyclodextrin derivatives, their synthesis, NMR characterization, and binding of 6alpha-methylprednisolone. Journal of Pharmaceutical Sciences. 94: 2380-92. PMID 16200617 DOI: 10.1002/Jps.20367  0.359
2004 Okimoto K, Tokunaga Y, Ibuki R, Irie T, Uekama K, Rajewski RA, Stella VJ. Applicability of (SBE)7m-beta-CD in controlled-porosity osmotic pump tablets (OPTs). International Journal of Pharmaceutics. 286: 81-8. PMID 15501004 DOI: 10.1016/J.Ijpharm.2004.08.002  0.426
2004 Jumaa M, Carlson B, Chimilio L, Silchenko S, Stella VJ. Kinetics and mechanism of degradation of epothilone-D: An experimental anticancer agent Journal of Pharmaceutical Sciences. 93: 2953-2961. PMID 15459947 DOI: 10.1002/Jps.20196  0.354
2004 Jumaa M, Chimilio L, Chinnaswamy S, Silchenko S, Stella VJ. Degradation of NSC-281612 (4-[bis[2-[(Methylsulfonyl)-oxy]ethyl]amino]-2-methyl-benzaldehyde), an Experimental Antineoplastic Agent: Effects of pH, Solvent Composition, (SBE)7m-β-CD, and HP-β-CD on Stability Journal of Pharmaceutical Sciences. 93: 532-539. PMID 14762892 DOI: 10.1002/Jps.10571  0.359
2004 Stella VJ. Prodrugs as therapeutics Expert Opinion On Therapeutic Patents. 14: 277-280. DOI: 10.1517/13543776.14.3.277  0.384
2003 Silchenko S, Schöneich C, Carlson BJ, Stella VJ. Photostability of 2-hydroxymethyl-4,8-dibenzo[1,2-b:5,4-b′] dithiophene-4,8-dione (NSC 656240), a potential anticancer drug International Journal of Pharmaceutics. 264: 97-105. PMID 12972339 DOI: 10.1016/S0378-5173(03)00393-4  0.399
2003 Hanson BA, Schowen RL, Stella VJ. A mechanistic and kinetic study of the E-ring hydrolysis and lactonization of a novel phosphoryloxymethyl prodrug of camptothecin. Pharmaceutical Research. 20: 1031-8. PMID 12880289 DOI: 10.1023/A:1024410322870  0.351
2003 Rao VM, Stella VJ. When can cyclodextrins be considered for solubilization purposes? Journal of Pharmaceutical Sciences. 92: 927-32. PMID 12712411 DOI: 10.1002/Jps.10341  0.591
2002 Stella VJ, Rao VM, Zannou EA. The pharmaceutical use of Captisol®: Some surprising observations Journal of Inclusion Phenomena. 44: 29-33. DOI: 10.1023/A:1023068414272  0.794
2001 Zannou EA, Streng WH, Stella VJ. Osmotic properties of sulfobutylether and hydroxypropyl cyclodextrins. Pharmaceutical Research. 18: 1226-31. PMID 11587496 DOI: 10.1023/A:1010947631380  0.791
2001 Rao VM, Haslam JL, Stella VJ. Controlled and complete release of a model poorly water-soluble drug, prednisolone, from hydroxypropyl methylcellulose matrix tablets using (SBE)(7m)-beta-cyclodextrin as a solubilizing agent. Journal of Pharmaceutical Sciences. 90: 807-16. PMID 11458330 DOI: 10.1002/Jps.1034  0.619
2000 Wu S, Waugh W, Stella VJ. Degradation pathways of a peptide boronic acid derivative, 2-Pyz-(CO)-Phe-Leu-B(OH)2 Journal of Pharmaceutical Sciences. 89: 758-765. PMID 10824134 DOI: 10.1002/(Sici)1520-6017(200006)89:6<758::Aid-Jps7>3.0.Co;2-L  0.345
2000 Antipas AS, Vander Velde DG, Jois SD, Siahaan T, Stella VJ. Effect of conformation on the rate of deamidation of vancomycin in aqueous solutions. Journal of Pharmaceutical Sciences. 89: 742-50. PMID 10824132 DOI: 10.1002/(Sici)1520-6017(200006)89:6<742::Aid-Jps5>3.0.Co;2-9  0.348
2000 Ma DQ, Rajewski RA, Velde DV, Stella VJ. Comparative effects of (SBE)(7m)-β-CD and hp-β-cd on the stability of two anti-neoplastic agents, melphalan and carmustine Journal of Pharmaceutical Sciences. 89: 275-287. PMID 10688757 DOI: 10.1002/(Sici)1520-6017(200002)89:2<275::Aid-Jps15>3.0.Co;2-C  0.314
1999 Stella VJ, Rao VM, Zannou EA, Zia V. Mechanisms of drug release from cyclodextrin complexes. Advanced Drug Delivery Reviews. 36: 3-16. PMID 10837705 DOI: 10.1016/S0169-409X(98)00052-0  0.795
1999 Haslam JL, Egodage KL, Chen Y, Rajewski RA, Stella V. Stability of rifabutin in two extemporaneously compounded oral liquids. American Journal of Health-System Pharmacy : Ajhp : Official Journal of the American Society of Health-System Pharmacists. 56: 333-6. PMID 10690216 DOI: 10.1093/Ajhp/56.4.333  0.302
1999 Ma DQ, Rajewski RA, Stella VJ. New injectable melphalan formulations utilizing (SBE)(7m)-β-CD or HP-β-CD International Journal of Pharmaceutics. 189: 227-234. PMID 10536251 DOI: 10.1016/S0378-5173(99)00255-0  0.313
1999 Stella VJ, Martodihardjo S, Terada K, Rao VM. Some relationships between the physical properties of various 3-acyloxymethyl prodrugs of phenytoin to structure: potential in vivo performance implications Journal of Pharmaceutical Sciences. 88: 1100. PMID 10514361  0.492
1999 Krise JP, Charman WN, Charman SA, Stella VJ. A novel prodrug approach for tertiary amines. 3. In vivo evaluation of two N-phosphonooxymethyl prodrugs in rats and dogs Journal of Pharmaceutical Sciences. 88: 928-932. PMID 10479356 DOI: 10.1021/Js980382V  0.364
1999 Krise JP, Narisawa S, Stella VJ. A novel prodrug approach for tertiary amines. 2. Physicochemical and in vitro enzymatic evaluation of selected N-phosphonooxymethyl prodrugs Journal of Pharmaceutical Sciences. 88: 922-927. PMID 10479355 DOI: 10.1021/Js9803813  0.428
1999 Simon LD, Stella VJ, Charman WN, Charman SA. Variation in the diffusion and release of ribonuclease through and from esterified hyaluronic acid membranes: Effect of changes in matrix characteristics Journal of Controlled Release. 61: 159-164. PMID 10469912 DOI: 10.1016/S0168-3659(99)00115-7  0.337
1999 Krise JP, Zygmunt J, Georg GI, Stella VJ. Novel prodrug approach for tertiary amines: synthesis and preliminary evaluation of N-phosphonooxymethyl prodrugs. Journal of Medicinal Chemistry. 42: 3094-100. PMID 10447953 DOI: 10.1021/Jm980539W  0.445
1999 Stella VJ, Martodihardjo S, Rao VM. Aqueous solubility and dissolution rate does not adequately predict in vivo performance: a probe utilizing some N-acyloxymethyl phenytoin prodrugs. Journal of Pharmaceutical Sciences. 88: 775-9. PMID 10430541 DOI: 10.1021/Js980489I  0.604
1999 Okimoto K, Ohike A, Ibuki R, Aoki O, Ohnishi N, Rajewski RA, Stella VJ, Irie T, Uekama K. Factors affecting membrane-controlled drug release for an osmotic pump tablet (OPT) utilizing (SBE)(7m)-beta-CD as both a solubilizer and osmotic agent. Journal of Controlled Release : Official Journal of the Controlled Release Society. 60: 311-9. PMID 10425336 DOI: 10.1016/S0168-3659(99)00077-2  0.338
1999 Okimoto K, Ohike A, Ibuki R, Aoki O, Ohnishi N, Irie T, Uekama K, Rajewski RA, Stella VJ. Design and Evaluation of an Osmotic Pump Tablet (OPT) for Chlorpromazine Using (SBE)7m-β-CD Pharmaceutical Research. 16: 549-554. PMID 10227711 DOI: 10.1023/A:1018827214223  0.341
1999 Okimoto K, Rajewski RA, Stella VJ. Release of testosterone from an osmotic pump tablet utilizing (SBE)(7m)-β-cyclodextrin as both a solubilizing and an osmotic pump agent Journal of Controlled Release. 58: 29-38. PMID 10021487 DOI: 10.1016/S0168-3659(98)00142-4  0.324
1999 Yoshikawa T, Sakaeda T, Sugawara T, Hirano K, Stella VJ. A novel chemical delivery system for brain targeting Advanced Drug Delivery Reviews. 36: 255-275. DOI: 10.1016/S0169-409X(98)00091-X  0.347
1998 Stella VJ, Martodihardjo S, Terada K, Rao VM. Some relationships between the physical properties of various 3-acyloxymethyl prodrugs of phenytoin to structure: potential in vivo performance implications. Journal of Pharmaceutical Sciences. 87: 1235-41. PMID 9758683 DOI: 10.1021/Js980008V  0.622
1998 Medlicott NJ, Foster KA, Audus KL, Gupta S, Stella VJ. Comparison of the effects of potential parenteral vehicles for poorly water soluble anticancer drugs (organic cosolvents and cyclodextrin solutions) on cultured endothelial cells (HUV-EC). Journal of Pharmaceutical Sciences. 87: 1138-43. PMID 9724567 DOI: 10.1021/Js9704442  0.334
1998 Narisawa S, Stella VJ. Increased shelf-life of fosphenytoin: Solubilization of a degradant, phenytoin, through complexation with (SBE)(7m)-β-CD Journal of Pharmaceutical Sciences. 87: 926-930. PMID 9687335 DOI: 10.1021/Js980041H  0.333
1997 Gangwar S, Pauletti GM, Siahaan TJ, Stella VJ, Borchardt RT. Synthesis of a novel esterase-sensitive cyclic prodrug of a hexapeptide using an (acyloxy)alkoxy promoiety Journal of Organic Chemistry. 62: 1356-1362. DOI: 10.1021/Jo961696A  0.343
1997 Jarho P, Järvinen K, Urtti A, Stella VJ, Järvinen T. The use of cyclodextrins in ophthalmic formulations of dipivefrin International Journal of Pharmaceutics. 153: 225-233. DOI: 10.1016/S0378-5173(97)00111-7  0.314
1997 Simon LD, Charman WN, Charman SA, Stella VJ. Protein transport across hydrated hyaluronic acid ester membranes: Evaluation of ribonuclease A as a potentially useful model protein Journal of Controlled Release. 45: 273-285. DOI: 10.1016/S0168-3659(96)01593-3  0.34
1997 Gangwar S, Pauletti GM, Wang B, Siahaan TJ, Stella VJ, Borchardt RT. Novel esterase-sensitive cyclic prodrugs of a model hexapeptide having enhanced membrane permeability and enzymatic stability Pharmacochemistry Library. 28: 27-34. DOI: 10.1016/S0165-7208(97)80050-5  0.355
1996 Okimoto K, Rajewski RA, Uekama K, Jona JA, Stella VJ. The interaction of charged and uncharged drugs with neutral (HP-β-CD) and anionically charged (SBE7-β-CD) β-cyclodextrins Pharmaceutical Research. 13: 256-264. PMID 8932446 DOI: 10.1023/A:1016047215907  0.315
1996 Rajewski RA, Stella VJ. Pharmaceutical applications of cyclodextrins. 2. In vivo drug delivery Journal of Pharmaceutical Sciences. 85: 1142-1169. PMID 8923319 DOI: 10.1021/Js960075U  0.334
1996 Luna EA, Bornancini ER, Tait RJ, Thompson DO, Stobaugh JF, Rajewski RA, Stella VJ. Evaluation of the utility of capillary electrophoresis for the analysis of sulfobutyl ether beta-cyclodextrin mixtures. Journal of Pharmaceutical and Biomedical Analysis. 15: 63-71. PMID 8895077 DOI: 10.1016/0731-7085(96)01826-2  0.333
1996 Stella VJ. A case for prodrugs: Fosphenytoin Advanced Drug Delivery Reviews. 19: 311-330. DOI: 10.1016/0169-409X(95)00112-K  0.426
1996 Krise JP, Stella VJ. Prodrugs of phosphates, phosphonates, and phosphinates Advanced Drug Delivery Reviews. 19: 287-310. DOI: 10.1016/0169-409X(95)00111-J  0.38
1995 Gorecka BA, Sanzgiri YD, Bindra DS, Stella VJ. Effect of SBE4-β-CD, a sulfobutyl ether β-cyclodextrin, on the stability and solubility of O6-benzylguanine (NSC-637037) in aqueous solutions International Journal of Pharmaceutics. 125: 55-61. DOI: 10.1016/0378-5173(95)00112-V  0.341
1995 Pochopin NL, Charman WN, Stella VJ. Amino acid derivatives of dapsone as water-soluble prodrugs International Journal of Pharmaceutics. 121: 157-167. DOI: 10.1016/0378-5173(95)00005-4  0.433
1995 Stella VJ, Lee HK, Thompson DO. The effect of SBE4-β-CD on i.m. prednisolone pharmacokinetics and tissue damage in rabbits: Comparison to a co-solvent solution and a water-soluble prodrug International Journal of Pharmaceutics. 120: 197-204. DOI: 10.1016/0378-5173(94)00405-T  0.344
1995 Stella VJ, Lee HK, Thompson DO. The effect of SBE4-β-CD on i.v. methylprednisolone pharmacokinetics in rats: Comparison to a co-solvent solution and two water-soluble prodrugs International Journal of Pharmaceutics. 120: 189-195. DOI: 10.1016/0378-5173(94)00404-S  0.36
1994 Oliyai R, Safadi M, Meier PG, Hu MK, Rich DH, Stella VJ. Kinetics of acid-catalyzed degradation of cyclosporin A and its analogs in aqueous solution. International Journal of Peptide and Protein Research. 43: 239-47. PMID 8005746 DOI: 10.1111/J.1399-3011.1994.Tb00386.X  0.409
1994 Bindra DS, Williams TD, Stella VJ. Degradation of O6-benzylguanine in aqueous polyethylene glycol 400 (PEG 400) solutions: concerns with formaldehyde in PEG 400. Pharmaceutical Research. 11: 1060-4. PMID 7937549 DOI: 10.1023/A:1018903908385  0.383
1994 Järvinen K, Järvinen T, Thompson DO, Stella VJ. The effect of a modified βcyclodextrin, SBE4-βCD, on the aqueous stability and ocular absorption of pilocarpine Current Eye Research. 13: 897-905. PMID 7720398 DOI: 10.3109/02713689409015093  0.333
1994 Simon LD, Ruiz-Cardona L, Topp EM, Stella VJ. Effect of ph on theophylline release from partially esterifted alginic acid matrices Drug Development and Industrial Pharmacy. 20: 2341-2351. DOI: 10.3109/03639049409042641  0.399
1994 Pochopin NL, Charman WN, Stella VJ. Kinetics of rearrangement and hydrolysis of amino acid derivatives of prazosin International Journal of Pharmaceutics. 105: 169-176. DOI: 10.1016/0378-5173(94)90462-6  0.409
1994 Sanzgiri YD, Topp EM, Benedetti L, Stella VJ. Evaluation of mucoadhesive properties of hyaluronic acid benzyl esters International Journal of Pharmaceutics. 107: 91-97. DOI: 10.1016/0378-5173(94)90446-4  0.304
1994 Antipas AS, Velde DV, Stella VJ. Factors affecting the deamidation of vancomycin in aqueous solutions International Journal of Pharmaceutics. 109: 261-269. DOI: 10.1016/0378-5173(94)90388-3  0.341
1994 Hume LR, Lee HK, Benedetti L, Sanzgiri YD, Topp EM, Stella VJ. Ocular sustained delivery of prednisolone using hyaluronic acid benzyl ester films International Journal of Pharmaceutics. 111: 295-298. DOI: 10.1016/0378-5173(94)90352-2  0.312
1994 Müller DG, Stella VJ, Lötter AP. Determination of the position of the ester bond in a micellar prodrug of phenytoin International Journal of Pharmaceutics. 102: 109-116. DOI: 10.1016/0378-5173(94)90045-0  0.357
1993 Kearney AS, Stella VJ. Hydrolysis of pharmaceutically relevant phosphate monoester monoanions: Correlation to an established structure-reactivity relationship Journal of Pharmaceutical Sciences. 82: 69-72. PMID 8429495 DOI: 10.1002/Jps.2600820115  0.352
1993 Safadi M, Oliyai R, Stella VJ. Phosphoryloxymethyl Carbamates and Carbonates—Novel Water-Soluble Prodrugs for Amines and Hindered Alcohols Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 10: 1350-1355. PMID 8234176 DOI: 10.1023/A:1018934200343  0.325
1993 Kagel JR, Stella VJ, Riley CM. A liquid chromatographic method for the determination of the enantiomeric purity of the anticancer drug, 9-amino-20(S)-camptothecin Journal of Pharmaceutical and Biomedical Analysis. 11: 793-802. PMID 8218523 DOI: 10.1016/0731-7085(93)80071-8  0.321
1993 Safadi M, Bindra DS, Williams T, Moschel RC, Stella VJ. Kinetics and mechanism of the acid-catalyzed hydrolysis of O6-benzylguanine International Journal of Pharmaceutics. 90: 239-246. DOI: 10.1016/0378-5173(93)90196-M  0.342
1993 Sanzgiri YD, Maschi S, Crescenzi V, Callegaro L, Topp EM, Stella VJ. Gellan-based systems for ophthalmic sustained delivery of methylprednisolone Journal of Controlled Release. 26: 195-201. DOI: 10.1016/0168-3659(93)90186-9  0.343
1993 Papini D, Stella VJ, Topp EM. Diffusion of macromolecules in membranes of hyalyronic acid esters Journal of Controlled Release. 27: 47-57. DOI: 10.1016/0168-3659(93)90056-B  0.306
1992 Kearney AS, Stella VJ. The Anomalous Hydrolytic Behavior of 1-Phenylvinyl Phosphate Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 9: 378-384. PMID 1614971 DOI: 10.1023/A:1015899120700  0.352
1992 Oliyai R, Stella VJ. Kinetics and Mechanism of Isomerization of Cyclosporin A Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 9: 617-622. PMID 1608891 DOI: 10.1023/A:1015841824760  0.383
1992 Southard MZ, Green DW, Stella VJ, Himmelstein KJ. Dissolution of lonizable Drugs into Unbuffered Solution: A Comprehensive Model for Mass Transport and Reaction in the Rotating Disk Geometry Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 9: 58-69. PMID 1589411 DOI: 10.1023/A:1018979727118  0.37
1992 Sisco JM, Stella VJ. An Unexpected Hydrolysis pH-Rate Profile, at pH Values Less than 7, of the Labile Imide, ICRF-187: (+)-1,2-Bis-(3,5 -dioxopiperazin-1-yl)propane Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 9: 1209-1214. PMID 1409406 DOI: 10.1023/A:1015868209198  0.373
1992 Sisco JM, Stella VJ. Is ICRF-187 [(+)-1,2-Bis(3,5-dioxopiperazinyl-1-yl)propane] Unusually Reactive for an Imide? Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 9: 1076-1082. PMID 1409381 DOI: 10.1023/A:1015818931062  0.343
1992 Fassberg J, Stella VJ. A kinetic and mechanistic study of the hydrolysis of camptothecin and some analogues Journal of Pharmaceutical Sciences. 81: 676-684. PMID 1403703 DOI: 10.1002/Jps.2600810718  0.358
1992 Mathew AE, Mejillano MR, Nath JP, Himes RH, Stella VJ. Synthesis and evaluation of some water-soluble prodrugs and derivatives of taxol with antitumor activity. Journal of Medicinal Chemistry. 35: 145-51. PMID 1346275 DOI: 10.1021/Jm00079A019  0.361
1992 Kyyrönen K, Hume L, Benedetti L, Urtti A, Topp E, Stella V. Methylprednisolone esters of hyaluronic acid in ophthalmic drug delivery: in vitro and in vivo release studies International Journal of Pharmaceutics. 80: 161-169. DOI: 10.1016/0378-5173(92)90274-6  0.4
1992 Müller DG, Stella VJ, Lötter AP. The determination of the amphiphilic properties of a prodrug (DDMS) of phenytoin in aqueous media International Journal of Pharmaceutics. 86: 175-186. DOI: 10.1016/0378-5173(92)90195-8  0.317
1992 Rajewski LG, Stinnett AA, Stella VJ, Topp EM. Enzymic and non-enzymic hydrolysis of a polymeric prodrug: Hydrocortisone esters of hyaluronic acid International Journal of Pharmaceutics. 82: 205-213. DOI: 10.1016/0378-5173(92)90176-3  0.371
1992 Joshi HN, Stella VJ, Topp EM. Drug release from membranes of hyaluronic acid and its esters Journal of Controlled Release. 20: 109-121. DOI: 10.1016/0168-3659(92)90157-M  0.396
1991 Stella VJ, Anderson WK, Benedetti A, Waugh WA, Killion RB. Stability of carmethizole hydrochloride (NSC-602668), an experimental cytotoxic agent International Journal of Pharmaceutics. 71: 157-165. DOI: 10.1016/0378-5173(91)90386-3  0.788
1991 Muller DG, Stella VJ, Lotter AP. Factors influencing the precipitation time of phenytoin in the presence of DDMS, one of its prodrugs International Journal of Pharmaceutics. 75: 201-209. DOI: 10.1016/0378-5173(91)90194-S  0.353
1991 Charman WN, Stella VJ. Transport of lipophilic molecules by the intestinal lymphatic system Advanced Drug Delivery Reviews. 7: 1-14. DOI: 10.1016/0169-409X(91)90046-F  0.327
1990 Naringrekar VH, Stella VJ. Mechanism of hydrolysis and structure-stability relationship of enaminones as potential prodrugs of model primary amines Journal of Pharmaceutical Sciences. 79: 138-146. PMID 2324962 DOI: 10.1002/Jps.2600790213  0.343
1990 Umprayn K, Waugh W, Stella VJ. Mechanism of degradation of the investigational cytotoxic agent, cyclodisone (NSC-348948) International Journal of Pharmaceutics. 66: 253-262. DOI: 10.1016/0378-5173(90)90406-T  0.356
1990 Killion RB, Stella VJ. The nucleophilicity of dextrose, sucrose, sorbitol, and mannitol with p-nitrophenyl esters in aqueous solution International Journal of Pharmaceutics. 66: 149-155. DOI: 10.1016/0378-5173(90)90394-J  0.763
1990 Al-Razzak LA, Stella VJ. Stability and solubility of 2-chloro-2′,3′-dideoxyadenosine International Journal of Pharmaceutics. 60: 53-60. DOI: 10.1016/0378-5173(90)90189-B  0.396
1990 Hunt JA, Joshi HN, Stella VJ, Topp EM. Diffusion and drug release in polymer films prepared from ester derivatives of hyaluronic acid Journal of Controlled Release. 12: 159-169. DOI: 10.1016/0168-3659(90)90092-8  0.317
1990 Benedetti LM, Topp EM, Stella VJ. Microspheres of hyaluronic acid esters-Fabrication methods and in vitro hydrocortisone release Journal of Controlled Release. 13: 33-41. DOI: 10.1016/0168-3659(90)90072-2  0.418
1989 Prankerd RJ, Stella VJ. Equilibria and kinetics of hydrolysis of ebifuramin (NSC-201047), an azomethine-containing structure exhibiting a reversible degradation step in acidic solutions International Journal of Pharmaceutics. 52: 71-78. DOI: 10.1016/0378-5173(89)90090-2  0.407
1988 Sendo F, Riley CM, Stella VJ. Kinetics of hydrolysis of fetindomide (NSC-373965), bis-N,N′-phenylalanyloxymethyl prodrug of mitindomide (NSC-284356); an unexpected catalytic effect of generated formaldehyde International Journal of Pharmaceutics. 45: 207-216. DOI: 10.1016/0378-5173(88)90290-6  0.36
1988 Stella VJ, Umprayn K, Waugh WN. Development of parenteral formulations of experimental cytotoxic agents. I. Rhizoxin (NSC-332598) International Journal of Pharmaceutics. 43: 191-199. DOI: 10.1016/0378-5173(88)90273-6  0.348
1988 Kennedy PE, Riley CM, Stella VJ. Degradation of the antineoplastic drug, clomesone (2-chloroethyl(methylsulfonyl) methanesulfonate, NSC-338947). A kinetic and mechanistic study International Journal of Pharmaceutics. 48: 179-188. DOI: 10.1016/0378-5173(88)90262-1  0.38
1988 Paborji M, Riley CM, Stella VJ. A novel use of Intralipid for the patenterai delivery of perilla ketone (NSC-348407), an investigational cytotoxic drug with a high affinity for plastic International Journal of Pharmaceutics. 42: 243-249. DOI: 10.1016/0378-5173(88)90181-0  0.343
1988 Anderson BD, Wygant MB, Tian-Xiang X, Waugh WA, Stella VJ. Preformulation solubility and kinetic studies of 2',3'-dideoxypurine nucleosides: potential anti-AIDS agents International Journal of Pharmaceutics. 45: 27-37. DOI: 10.1016/0378-5173(88)90031-2  0.643
1987 Paborji M, Waugh WN, Stella VJ. Mechanistic investigation of the degradation of sulfamic acid 17,heptanediyl ester, an experimental cytotoxic agent, in water and 18Oxygen-enriched water Journal of Pharmaceutical Sciences. 76: 161-165. PMID 3572756 DOI: 10.1002/Jps.2600760216  0.387
1987 Umprayn K, Stella VJ, Riley CM. Stability indicating assay for fetindomide (NSC 373965), a potential prodrug of mitindomide (NSC 284356), employing high-performance liquid chromatography Journal of Pharmaceutical and Biomedical Analysis. 5: 675-685. DOI: 10.1016/0731-7085(87)80080-8  0.321
1987 Umprayn K, Kennedy PE, Lee JC, Waugh W, Riley CM, Stella VJ. Development of reversed-phase HPLC assays for cyclodisone and clomesone Journal of Pharmaceutical and Biomedical Analysis. 5: 625-633. DOI: 10.1016/0731-7085(87)80075-4  0.347
1986 Charman WNA, Noguchi T, Stella VJ. Testing potential dosage form strategies for intestinal lymphatic drug transport: studies in the rat International Journal of Pharmaceutics. 33: 173-179. DOI: 10.1016/0378-5173(86)90051-7  0.34
1986 Charman WNA, Stella VJ. Estimating the maximal potential for intestinal lymphatic transport of lipophilic drug molecules International Journal of Pharmaceutics. 34: 175-178. DOI: 10.1016/0378-5173(86)90027-X  0.334
1985 Aunins JG, Southard MZ, Myers RA, Himmelstein KJ, Stella VJ. Dissolution of carboxylic acids. III: The effect of polyionizable buffers. Journal of Pharmaceutical Sciences. 74: 1305-16. PMID 4087198 DOI: 10.1002/Jps.2600741212  0.39
1985 Jivani SG, Stella VJ. Mechanism of decarboxylation of p-aminosalicylic acid Journal of Pharmaceutical Sciences. 74: 1274-1282. PMID 4087194 DOI: 10.1002/Jps.2600741207  0.394
1985 Stella VJ, Charman WNA, Naringrekar VH. Prodrugs: Do They Have Advantages in Clinical Practice? Drugs. 29: 455-473. PMID 3891303 DOI: 10.2165/00003495-198529050-00002  0.362
1985 Noguchi T, Charman WNA, Stella VJ. The effect of drug lipophilicity and lipid vehicles on the lymphatic absorption of various testosterone esters International Journal of Pharmaceutics. 24: 173-184. DOI: 10.1016/0378-5173(85)90018-3  0.338
1984 Varia SA, Stella VJ. Phenytoin prodrugs V: In vivo evaluation of some water-soluble phenytoin prodrugs in dogs Journal of Pharmaceutical Sciences. 73: 1080-1087. PMID 6548519 DOI: 10.1002/Jps.2600730814  0.38
1984 Varia SA, Schuller S, Sloan KB, Stella VJ. Phenytoin prodrugs III: Water-soluble prodrugs for oral and/or parenteral use Journal of Pharmaceutical Sciences. 73: 1068-1073. PMID 6491911 DOI: 10.1002/Chin.198504196  0.4
1984 Stella VJ, Mooney KG, Pipkin JD. Dissolution of ionization of warfarin Journal of Pharmaceutical Sciences. 73: 946-948. PMID 6470958 DOI: 10.1002/Jps.2600730721  0.387
1983 Yamaoka Y, Roberts RD, Stella VJ. Low-melting phenytoin prodrugs as alternative oral delivery modes for phenytoin: a model for other high-melting sparingly water-soluble drugs. Journal of Pharmaceutical Sciences. 72: 400-5. PMID 6864479 DOI: 10.1002/Jps.2600720420  0.436
1983 Williams DB, Varia SA, Stella VJ, Pitman IH. Evaluation of the prodrug potential of the sulfate esters of acetaminophen and 3-hydroxymethyl-phenytoin International Journal of Pharmaceutics. 14: 113-120. DOI: 10.1016/0378-5173(83)90119-9  0.323
1982 Bundgaard H, Johansen M, Stella V, Cortese M. Pro-drugs as drug delivery systems XXI. Preparation, physicochemical properties and bioavailability of a novel water-soluble pro-drug type for carbamazepine☆ International Journal of Pharmaceutics. 10: 181-192. DOI: 10.1016/0378-5173(82)90068-0  0.445
1981 Mooney KG, Rodriguez-Gaxiola M, Mintun M, Himmelstein KJ, Stella VJ. Dissolution kinetics of phenylbutazone Journal of Pharmaceutical Sciences. 70: 1358-1365. PMID 7320853 DOI: 10.1002/Jps.2600701218  0.386
1981 Mooney KG, Mintun MA, Himmelstein KJ, Stella VJ. Dissolution kinetics of carboxylic acids II: Effect of buffers Journal of Pharmaceutical Sciences. 70: 22-32. PMID 7229926 DOI: 10.1002/Jps.2600700104  0.351
1981 Mooney KG, Mintun MA, Himmelstein KJ, Stella VJ. Dissolution kinetics of carboxylic acids I: Effect of pH under unbuffered conditions Journal of Pharmaceutical Sciences. 70: 13-22. PMID 7229925 DOI: 10.1002/Jps.2600700103  0.366
1980 Stella VJ, Himmelstein KJ. Prodrugs and site-specific drug delivery Journal of Medicinal Chemistry. 23: 1276-1282. PMID 7005447 DOI: 10.1002/Chin.198115351  0.332
1979 Stella VJ, Gish R. Kinetics and mechanism of ionization of the carbon acids 4'-substituted 2-phenyl-1,3-indandiones Journal of Pharmaceutical Sciences. 68: 1047-1049. PMID 39157 DOI: 10.1002/Jps.2600680833  0.399
1979 Stella VJ, Gish R. Ionization kinetics of the carbon acid phenindione Journal of Pharmaceutical Sciences. 68: 1042-1047. PMID 39156 DOI: 10.1002/Jps.2600680832  0.38
1979 Lee HK, Lambert H, Stella VJ, Wang D, Higuchi T. Hydrolysis and dissolution behavior of a prolonged release prodrug of theophylline: 7,7'-succinylditheophylline Journal of Pharmaceutical Sciences. 68: 288-295. PMID 34020 DOI: 10.1002/Jps.2600680309  0.548
1978 Stella V, Haslam J, Yata N, Okada H, Lindenbaum S, Higuchi T. Enhancement of bioavailability of a hydrophobic amine antimalarial by formulation with oleic acid in a soft gelatin capsule. Journal of Pharmaceutical Sciences. 67: 1375-7. PMID 702283 DOI: 10.1002/Jps.2600671011  0.574
1977 Kimura T, Sternson LA, Stella VJ, Higuchi T. A preliminary pharmacokinetic study of dianhydrogalactitol (NSC-132313) disposition in the dog Journal of the National Cancer Institute. 58: 1311-1314. PMID 857026 DOI: 10.1093/jnci/58.5.1311  0.451
1976 Stella VJ, Pipkin JD. Phenylbutazone ionization kinetics Journal of Pharmaceutical Sciences. 65: 1161-1165. PMID 10411 DOI: 10.1002/Jps.2600650808  0.386
1975 Haddadin MJ, Higuchi T, Stella V. Solvolytic reactions of cyclic anhydrides in anhydrous acetic acid. Journal of Pharmaceutical Sciences. 64: 1759-65. PMID 1195105 DOI: 10.1002/Jps.2600641105  0.549
1975 Haddadin MJ, Higuchi T, Stella V. Acylation of phenol by cyclic and acyclic anhydrides in anhydrous acetic acid. Journal of Pharmaceutical Sciences. 64: 1766-70. PMID 172623 DOI: 10.1002/Jps.2600641106  0.539
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