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Ulf Schmitz - Publications

Affiliations: 
Systems Biology and Bioinformatics Group University of Rostock, Rostock, Mecklenburg-Vorpommern, Germany 
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Lai X, Schmitz U, Vera J. The Role of MicroRNAs in Cancer Biology and Therapy from a Systems Biology Perspective. Advances in Experimental Medicine and Biology. 1385: 1-22. PMID 36352209 DOI: 10.1007/978-3-031-08356-3_1  0.304
2020 Alharbi AB, Schmitz U, Marshall AD, Vanichkina D, Nagarajah R, Vellozzi M, Wong JJ, Bailey CG, Rasko JE. haploinsufficiency mediates intron retention in a tissue-specific manner. Rna Biology. 1-11. PMID 32816606 DOI: 10.1080/15476286.2020.1796052  0.322
2020 Emran AA, Nsengimana J, Punnia-Moorthy G, Schmitz U, Gallagher SJ, Newton-Bishop J, Tiffen JC, Hersey P. Study of the Female Sex Survival Advantage in Melanoma-A Focus on X-Linked Epigenetic Regulators and Immune Responses in Two Cohorts. Cancers. 12: 2082. PMID 32731355 DOI: 10.3390/Cancers12082082  0.314
2020 Green ID, Pinello N, Song R, Lee Q, Halstead JM, Kwok CT, Wong ACH, Nair SS, Clark SJ, Roediger B, Schmitz U, Larance M, Hayashi R, Rasko JEJ, Wong JJ. Macrophage development and activation involve coordinated intron retention in key inflammatory regulators. Nucleic Acids Research. PMID 32449925 DOI: 10.1093/Nar/Gkaa435  0.308
2019 Monteuuis G, Wong JJL, Bailey CG, Schmitz U, Rasko JEJ. The changing paradigm of intron retention: regulation, ramifications and recipes. Nucleic Acids Research. PMID 31724706 DOI: 10.1093/Nar/Gkz1068  0.345
2019 Amirkhah R, Naderi-Meshkin H, Shah JS, Dunne PD, Schmitz U. The Intricate Interplay between Epigenetic Events, Alternative Splicing and Noncoding RNA Deregulation in Colorectal Cancer. Cells. 8. PMID 31430887 DOI: 10.3390/Cells8080929  0.336
2019 Lai X, Eberhardt M, Schmitz U, Vera J. Systems biology-based investigation of cooperating microRNAs as monotherapy or adjuvant therapy in cancer. Nucleic Acids Research. PMID 31340025 DOI: 10.1093/Nar/Gkz638  0.403
2019 Naderi-Meshkin H, Lai X, Amirkhah R, Vera J, Rasko JEJ, Schmitz U. Exosomal lncRNAs and cancer: connecting the missing links. Bioinformatics (Oxford, England). 35: 352-360. PMID 30649349 DOI: 10.1093/Bioinformatics/Bty527  0.322
2019 Lai X, Eberhardt M, Gupta SK, Schmitz U, Marquardt S, Knoll S, Spitschak A, Wolkenhauer O, Pützer BM, Vera J. MiR-205-5p and miR-342-3p cooperate in the repression of the E2F1 transcription factor in the context of anticancer chemotherapy resistance F1000research. 8. DOI: 10.7490/F1000Research.1117216.1  0.318
2018 Rajasekhar M, Schmitz U, Flamant S, Wong JJ, Bailey CG, Ritchie W, Holst J, Rasko JEJ. Identifying microRNA determinants of human myelopoiesis. Scientific Reports. 8: 7264. PMID 29739970 DOI: 10.1038/S41598-018-24203-7  0.414
2018 Lai X, Gupta SK, Schmitz U, Marquardt S, Knoll S, Spitschak A, Wolkenhauer O, Pützer BM, Vera J. MiR-205-5p and miR-342-3p cooperate in the repression of the E2F1 transcription factor in the context of anticancer chemotherapy resistance. Theranostics. 8: 1106-1120. PMID 29464002 DOI: 10.7150/Thno.19904  0.428
2017 Schmitz U, Pinello N, Jia F, Alasmari S, Ritchie W, Keightley MC, Shini S, Lieschke GJ, Wong JJ, Rasko JEJ. Intron retention enhances gene regulatory complexity in vertebrates. Genome Biology. 18: 216. PMID 29141666 DOI: 10.1186/S13059-017-1339-3  0.324
2017 Khan FM, Marquardt S, Gupta SK, Knoll S, Schmitz U, Spitschak A, Engelmann D, Vera J, Wolkenhauer O, Pützer BM. Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures. Nature Communications. 8: 198. PMID 28775339 DOI: 10.1038/S41467-017-00268-2  0.337
2017 Vanichkina DP, Schmitz U, Wong JJ, Rasko JEJ. Challenges in defining the role of intron retention in normal biology and disease. Seminars in Cell & Developmental Biology. PMID 28739339 DOI: 10.1016/J.Semcdb.2017.07.030  0.34
2017 Amirkhah R, Meshkin HN, Farazmand A, Rasko JEJ, Schmitz U. Computational and Experimental Identification of Tissue-Specific MicroRNA Targets. Methods in Molecular Biology (Clifton, N.J.). 1580: 127-147. PMID 28439832 DOI: 10.1007/978-1-4939-6866-4_11  0.378
2017 Marshall AD, Bailey CG, Champ K, Vellozzi M, O'Young P, Metierre C, Feng Y, Thoeng A, Richards AM, Schmitz U, Biro M, Jayasinghe R, Ding L, Anderson L, Mardis ER, et al. CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic. Oncogene. PMID 28319062 DOI: 10.1038/Onc.2017.25  0.314
2016 Sadeghi M, Ranjbar B, Ganjalikhany MR, M Khan F, Schmitz U, Wolkenhauer O, Gupta SK. MicroRNA and Transcription Factor Gene Regulatory Network Analysis Reveals Key Regulatory Elements Associated with Prostate Cancer Progression. Plos One. 11: e0168760. PMID 28005952 DOI: 10.1371/Journal.Pone.0168760  0.416
2016 Edwards CR, Ritchie W, Wong JJ, Schmitz U, Middleton R, An X, Mohandas N, Rasko JE, Blobel GA. A dynamic intron retention program in the mammalian megakaryocyte and erythrocyte lineages. Blood. PMID 26962124 DOI: 10.1182/Blood-2016-01-692764  0.325
2016 Wong JJ, Au AY, Gao D, Pinello N, Kwok CT, Thoeng A, Lau KA, Gordon JE, Schmitz U, Feng Y, Nguyen TV, Middleton R, Bailey CG, Holst J, Rasko JE, et al. RBM3 regulates temperature sensitive miR-142-5p and miR-143 (thermomiRs), which target immune genes and control fever. Nucleic Acids Research. PMID 26825461 DOI: 10.1093/Nar/Gkw041  0.374
2016 Amirkhah R, Farazmand A, Wolkenhauer O, Schmitz U. RNA Systems Biology for Cancer: From Diagnosis to Therapy. Methods in Molecular Biology (Clifton, N.J.). 1386: 305-30. PMID 26677189 DOI: 10.1007/978-1-4939-3283-2_14  0.319
2015 Schmitz U, Naderi-Meshkin H, Gupta SK, Wolkenhauer O, Vera J. The RNA world in the 21st century-a systems approach to finding non-coding keys to clinical questions. Briefings in Bioinformatics. PMID 26330575 DOI: 10.1093/Bib/Bbv061  0.338
2015 Amirkhah R, Farazmand A, Gupta SK, Ahmadi H, Wolkenhauer O, Schmitz U. Naïve Bayes classifier predicts functional microRNA target interactions in colorectal cancer. Molecular Biosystems. 11: 2126-34. PMID 26086375 DOI: 10.1039/C5Mb00245A  0.388
2015 Bhattacharya A, Schmitz U, Raatz Y, Schönherr M, Kottek T, Schauer M, Franz S, Saalbach A, Anderegg U, Wolkenhauer O, Schadendorf D, Simon JC, Magin T, Vera J, Kunz M. miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy. Oncotarget. 6: 2966-80. PMID 25650662 DOI: 10.18632/Oncotarget.3070  0.368
2015 Amirkhah R, Schmitz U, Linnebacher M, Wolkenhauer O, Farazmand A. MicroRNA-mRNA interactions in colorectal cancer and their role in tumor progression. Genes, Chromosomes & Cancer. 54: 129-41. PMID 25620079 DOI: 10.1002/Gcc.22231  0.428
2014 Knoll S, Fürst K, Kowtharapu B, Schmitz U, Marquardt S, Wolkenhauer O, Martin H, Pützer BM. E2F1 induces miR-224/452 expression to drive EMT through TXNIP downregulation. Embo Reports. 15: 1315-29. PMID 25341426 DOI: 10.15252/Embr.201439392  0.344
2014 Schmitz U, Lai X, Winter F, Wolkenhauer O, Vera J, Gupta SK. Cooperative gene regulation by microRNA pairs and their identification using a computational workflow. Nucleic Acids Research. 42: 7539-52. PMID 24875477 DOI: 10.1093/Nar/Gku465  0.413
2014 Khan FM, Schmitz U, Nikolov S, Engelmann D, Pützer BM, Wolkenhauer O, Vera J. Hybrid modeling of the crosstalk between signaling and transcriptional networks using ordinary differential equations and multi-valued logic. Biochimica Et Biophysica Acta. 1844: 289-98. PMID 23692959 DOI: 10.1016/J.Bbapap.2013.05.007  0.312
2013 Lai X, Bhattacharya A, Schmitz U, Kunz M, Vera J, Wolkenhauer O. A systems' biology approach to study microRNA-mediated gene regulatory networks. Biomed Research International. 2013: 703849. PMID 24350286 DOI: 10.1155/2013/703849  0.424
2013 Vera J, Schmitz U, Lai X, Engelmann D, Khan FM, Wolkenhauer O, Pützer BM. Kinetic modeling-based detection of genetic signatures that provide chemoresistance via the E2F1-p73/DNp73-miR-205 network. Cancer Research. 73: 3511-24. PMID 23447575 DOI: 10.1158/0008-5472.Can-12-4095  0.372
2013 Schmitz U, Wolkenhauer O. Web resources for microRNA research. Advances in Experimental Medicine and Biology. 774: 225-50. PMID 23377976 DOI: 10.1007/978-94-007-5590-1_12  0.353
2013 Vera J, Lai X, Schmitz U, Wolkenhauer O. MicroRNA-regulated networks: the perfect storm for classical molecular biology, the ideal scenario for systems biology. Advances in Experimental Medicine and Biology. 774: 55-76. PMID 23377968 DOI: 10.1007/978-94-007-5590-1_4  0.394
2013 Bhattacharya A, Schmitz U, Wolkenhauer O, Schönherr M, Raatz Y, Kunz M. Regulation of cell cycle checkpoint kinase WEE1 by miR-195 in malignant melanoma. Oncogene. 32: 3175-83. PMID 22847610 DOI: 10.1038/Onc.2012.324  0.354
2012 Alla V, Kowtharapu BS, Engelmann D, Emmrich S, Schmitz U, Steder M, Pützer BM. E2F1 confers anticancer drug resistance by targeting ABC transporter family members and Bcl-2 via the p73/DNp73-miR-205 circuitry. Cell Cycle (Georgetown, Tex.). 11: 3067-78. PMID 22871739 DOI: 10.4161/Cc.21476  0.346
2012 Lai X, Schmitz U, Gupta SK, Bhattacharya A, Kunz M, Wolkenhauer O, Vera J. Computational analysis of target hub gene repression regulated by multiple and cooperative miRNAs. Nucleic Acids Research. 40: 8818-34. PMID 22798498 DOI: 10.1093/Nar/Gks657  0.411
2011 Nikolov S, Vera J, Schmitz U, Wolkenhauer O. A model-based strategy to investigate the role of microRNA regulation in cancer signalling networks. Theory in Biosciences = Theorie in Den Biowissenschaften. 130: 55-69. PMID 20809366 DOI: 10.1007/S12064-010-0109-5  0.417
2010 Schultz J, Koczan D, Schmitz U, Ibrahim SM, Pilch D, Landsberg J, Kunz M. Tumor-promoting role of signal transducer and activator of transcription (Stat)1 in late-stage melanoma growth. Clinical & Experimental Metastasis. 27: 133-40. PMID 20180146 DOI: 10.1007/S10585-010-9310-7  0.308
2007 Hoffrogge R, Beyer S, Hübner R, Mikkat S, Mix E, Scharf C, Schmitz U, Pauleweit S, Berth M, Zubrzycki IZ, Christoph H, Pahnke J, Wolkenhauer O, Uhrmacher A, Völker U, et al. 2-DE profiling of GDNF overexpression-related proteome changes in differentiating ST14A rat progenitor cells. Proteomics. 7: 33-46. PMID 17146836 DOI: 10.1002/Pmic.200600614  0.308
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