Year |
Citation |
Score |
2024 |
Fluegel LL, Deng MR, Su P, Kalkreuter E, Yang D, Rudolf JD, Dong LB, Shen B. Development of platensimycin, platencin, and platensilin overproducers by biosynthetic pathway engineering and fermentation medium optimization. Journal of Industrial Microbiology & Biotechnology. PMID 38262768 DOI: 10.1093/jimb/kuae003 |
0.486 |
|
2023 |
Wang Z, Yang Q, He J, Li H, Pan X, Li Z, Xu HM, Rudolf J, Tantillo D, Dong LB. Cytochrome P450 Mediated Cyclization in Eunicellane Derived Diterpenoid Biosynthesis. Angewandte Chemie (International Ed. in English). e202312490. PMID 37735947 DOI: 10.1002/anie.202312490 |
0.305 |
|
2022 |
Zheng YZ, Cui J, Wang YL, Huang SJ, Lin EC, Huang SC, Rudolf JD, Yan X, Chang CY. The Structure-Function Relationship of Human Bleomycin Hydrolase: Mutation of a Cysteine Protease into a Serine Protease. Chembiochem : a European Journal of Chemical Biology. e202200186. PMID 35467071 DOI: 10.1002/cbic.202200186 |
0.325 |
|
2021 |
Zhu C, Xu B, Adpressa DA, Rudolf JD, Loesgen S. Discovery and biosynthesis of a structurally dynamic antibacterial diterpenoid. Angewandte Chemie (International Ed. in English). PMID 33780586 DOI: 10.1002/anie.202102453 |
0.304 |
|
2020 |
Rudolf JD, Alsup TA, Xu B, Li Z. Bacterial terpenome. Natural Product Reports. PMID 33169126 DOI: 10.1039/d0np00066c |
0.334 |
|
2020 |
Zhang X, King-Smith E, Dong LB, Yang LC, Rudolf JD, Shen B, Renata H. Divergent synthesis of complex diterpenes through a hybrid oxidative approach. Science (New York, N.Y.). 369: 799-806. PMID 32792393 DOI: 10.1126/Science.Abb8271 |
0.496 |
|
2019 |
Rudolf JD, Chang CY. Terpene synthases in disguise: enzymology, structure, and opportunities of non-canonical terpene synthases. Natural Product Reports. PMID 31650156 DOI: 10.1039/c9np00051h |
0.317 |
|
2019 |
Dong LB, Liu YC, Cepeda AJ, Kalkreuter E, Deng MR, Rudolf JD, Chang C, Joachimiak A, Phillips GN, Shen B. Characterization and Crystal Structure of a Nonheme Diiron Monooxygenase Involved in Platensimycin and Platencin Biosynthesis. Journal of the American Chemical Society. PMID 31291107 DOI: 10.1021/jacs.9b06183 |
0.603 |
|
2019 |
Su M, Qiu L, Deng Y, Ruiz CH, Rudolf JD, Dong LB, Feng X, Cameron MD, Shen B, Duan Y, Huang Y. Evaluation of Platensimycin and Platensimycin-Inspired Thioether Analogues against Methicillin-Resistant Staphylococcus aureus in Topical and Systemic Infection Mouse Models. Molecular Pharmaceutics. PMID 31244223 DOI: 10.1021/Acs.Molpharmaceut.9B00293 |
0.491 |
|
2019 |
Dong LB, Zhang X, Shen B, Rudolf JD, Deng MR, Kalkreuter E, Cepeda AJ, Renata H. Cryptic and Stereospecific Hydroxylation, Oxidation, and Reduction in Platensimycin and Platencin Biosynthesis. Journal of the American Chemical Society. PMID 30735041 DOI: 10.1021/Jacs.8B13452 |
0.559 |
|
2018 |
Rudolf JD, Dong LB, Zhang X, Renata H, Shen B. Cytochrome P450-Catalyzed Hydroxylation Initiating Ether Formation in Platensimycin Biosynthesis. Journal of the American Chemical Society. PMID 30216060 DOI: 10.1021/Jacs.8B08012 |
0.558 |
|
2018 |
Annaval T, Han L, Rudolf JD, Xie G, Yang D, Chang CY, Ma M, Crnovcic I, Miller MD, Soman J, Xu W, Phillips GN, Shen B. Biochemical and structural characterization of TtnD, a prenylated FMN-dependent decarboxylase from the tautomycetin biosynthetic pathway. Acs Chemical Biology. PMID 30152678 DOI: 10.1021/Acschembio.8B00673 |
0.604 |
|
2018 |
Kwong T, Ma M, Pan G, Hindra, Yang D, Yang C, Lohman JR, Rudolf JD, Cleveland JL, Shen B. P450-Catalyzed Tailoring Steps in Leinamycin Biosynthesis Featuring Regio- and Stereoselective Hydroxylations and Substrate Promiscuities. Biochemistry. PMID 30070831 DOI: 10.1021/Acs.Biochem.8B00623 |
0.777 |
|
2018 |
Chang CY, Yan X, Crnovcic I, Annaval T, Chang C, Nocek B, Rudolf JD, Yang D, Hindra, Babnigg G, Joachimiak A, Phillips GN, Shen B. Resistance to Enediyne Antitumor Antibiotics by Sequestration. Cell Chemical Biology. PMID 29937405 DOI: 10.1016/J.Chembiol.2018.05.012 |
0.53 |
|
2018 |
Dong LB, Rudolf JD, Kang D, Wang N, He CQ, Deng Y, Huang Y, Houk KN, Duan Y, Shen B. Biosynthesis of thiocarboxylic acid-containing natural products. Nature Communications. 9: 2362. PMID 29915173 DOI: 10.1038/S41467-018-04747-Y |
0.573 |
|
2018 |
Wang N, Rudolf JD, Dong LB, Osipiuk J, Hatzos-Skintges C, Endres M, Chang CY, Babnigg G, Joachimiak A, Phillips GN, Shen B. Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme. Nature Chemical Biology. PMID 29867143 DOI: 10.1038/S41589-018-0061-0 |
0.563 |
|
2018 |
Shen B, Dong LB, Rudolf JD, Deng MR, Yan X. Discovery of the Tiancilactone Antibiotics by Genome Mining of Atypical Bacterial Type II Diterpene Synthases. Chembiochem : a European Journal of Chemical Biology. PMID 29806086 DOI: 10.1002/Cbic.201800285 |
0.581 |
|
2018 |
Chang CY, Lohman JR, Huang T, Michalska K, Bigelow L, Rudolf JD, Jedrzejczak R, Yan X, Ma M, Babnigg G, Joachimiak A, Phillips GN, Shen B. Structural Insights into the Free-standing Condensation Enzyme SgcC5 Catalyzing Ester Bond Formation in the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027. Biochemistry. PMID 29533601 DOI: 10.1021/Acs.Biochem.8B00174 |
0.746 |
|
2017 |
Annaval T, Rudolf JD, Chang CY, Lohman JR, Kim Y, Bigelow L, Jedrzejczak R, Babnigg G, Joachimiak A, Phillips GN, Shen B. Crystal Structure of Thioesterase SgcE10 Supporting Common Polyene Intermediates in 9- and 10-Membered Enediyne Core Biosynthesis. Acs Omega. 2: 5159-5169. PMID 28884166 DOI: 10.1021/acsomega.7b00933 |
0.744 |
|
2017 |
Rudolf JD, Chang CY, Ma M, Shen B. Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function. Natural Product Reports. PMID 28758170 DOI: 10.1039/C7Np00034K |
0.542 |
|
2017 |
Falzone M, Crespo E, Jones K, Khan G, Korn VL, Patel A, Patel M, Patel K, Perkins C, Siddiqui S, Stenger D, Yu E, Gelber M, Scheffler R, Nayda V, ... ... Rudolf JD, et al. Nutritional control of antibiotic production by Streptomyces platensis MA7327: importance of l-aspartic acid. The Journal of Antibiotics. PMID 28465627 DOI: 10.1038/Ja.2017.49 |
0.547 |
|
2017 |
Dong LB, Rudolf JD, Lin L, Ruiz C, Cameron MD, Shen B. In vivo instability of platensimycin and platencin: Synthesis and biological evaluation of urea- and carbamate-platensimycin. Bioorganic & Medicinal Chemistry. PMID 28237556 DOI: 10.1016/J.Bmc.2017.02.028 |
0.544 |
|
2016 |
Yan X, Ge H, Huang T, Hindra, Yang D, Teng Q, Crnovčić I, Li X, Rudolf JD, Lohman JR, Gansemans Y, Zhu X, Huang Y, Zhao LX, Jiang Y, et al. Strain Prioritization and Genome Mining for Enediyne Natural Products. Mbio. 7. PMID 27999165 DOI: 10.1128/Mbio.02104-16 |
0.741 |
|
2016 |
Rudolf JD, Dong LB, Manoogian K, Shen B. Biosynthetic Origin of the Ether Ring in Platensimycin. Journal of the American Chemical Society. PMID 27966343 DOI: 10.1021/Jacs.6B09818 |
0.597 |
|
2016 |
Rudolf JD, Dong LB, Shen B. Platensimycin and Platencin: Inspirations for Chemistry, Biology, Enzymology, and Medicine. Biochemical Pharmacology. PMID 27865713 DOI: 10.1016/J.Bcp.2016.11.013 |
0.578 |
|
2016 |
Dong LB, Rudolf JD, Shen B. A Mutasynthetic Library of Platensimycin and Platencin Analogues. Organic Letters. PMID 27599271 DOI: 10.1021/Acs.Orglett.6B02248 |
0.496 |
|
2016 |
Chang CY, Lohman JR, Cao H, Tan K, Rudolf JD, Ma M, Xu W, Bingman CA, Yennamalli RM, Bigelow L, Babnigg G, Yan X, Joachimiak A, Phillips GN, Shen B. Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase that Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate in Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus. Biochemistry. PMID 27560143 DOI: 10.1021/Acs.Biochem.6B00713 |
0.749 |
|
2016 |
Ma M, Rateb ME, Yang D, Rudolf JD, Zhu X, Huang Y, Zhao LX, Jiang Y, Duan Y, Shen B. Germicidins H-J from Streptomyces sp. CB00361. The Journal of Antibiotics. PMID 27507632 DOI: 10.1038/Ja.2016.100 |
0.421 |
|
2016 |
Rudolf JD, Dong LB, Cao H, Hatzos-Skintges C, Osipiuk J, Endres M, Chang CY, Ma M, Babnigg G, Joachimiak A, Phillips GN, Shen B. Structure of the ent-Copalyl Diphosphate Synthase PtmT2 from Streptomyces platensis CB00739, a Bacterial Type II Diterpene Synthase. Journal of the American Chemical Society. PMID 27490479 DOI: 10.1021/Jacs.6B04317 |
0.55 |
|
2016 |
Huang T, Chang CY, Lohman JR, Rudolf JD, Kim Y, Chang C, Yang D, Ma M, Yan X, Crnovcic I, Bigelow L, Clancy S, Bingman CA, Yennamalli RM, Babnigg G, et al. Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027. The Journal of Antibiotics. PMID 27406907 DOI: 10.1038/Ja.2016.88 |
0.75 |
|
2016 |
Dong LB, Rudolf JD, Shen B. Antibacterial sulfur-containing platensimycin and platencin congeners from Streptomyces platensis SB12029. Bioorganic & Medicinal Chemistry. PMID 27134119 DOI: 10.1016/J.Bmc.2016.04.026 |
0.578 |
|
2015 |
Rudolf JD, Bigelow L, Chang C, Cuff ME, Lohman JR, Chang CY, Ma M, Yang D, Clancy S, Babnigg G, Joachimiak A, Phillips GN, Shen B. Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892. Biochemistry. PMID 26512730 DOI: 10.1021/Acs.Biochem.5B01008 |
0.724 |
|
2015 |
Ma M, Rateb ME, Teng Q, Yang D, Rudolf JD, Zhu X, Huang Y, Zhao LX, Jiang Y, Li X, Rader C, Duan Y, Shen B. Angucyclines and Angucyclinones from Streptomyces sp. CB01913 Featuring C-Ring Cleavage and Expansion. Journal of Natural Products. PMID 26335269 DOI: 10.1021/Acs.Jnatprod.5B00601 |
0.561 |
|
2015 |
Rudolf JD, Yan X, Shen B. Genome neighborhood network reveals insights into enediyne biosynthesis and facilitates prediction and prioritization for discovery. Journal of Industrial Microbiology & Biotechnology. PMID 26318027 DOI: 10.1007/S10295-015-1671-0 |
0.53 |
|
2015 |
Rudolf JD, Dong LB, Huang T, Shen B. A genetically amenable platensimycin- and platencin-overproducer as a platform for biosynthetic explorations: a showcase of PtmO4, a long-chain acyl-CoA dehydrogenase. Molecular Biosystems. PMID 26055255 DOI: 10.1039/C5Mb00303B |
0.574 |
|
2015 |
Shen B, Hindra, Yan X, Huang T, Ge H, Yang D, Teng Q, Rudolf JD, Lohman JR. Enediynes: Exploration of microbial genomics to discover new anticancer drug leads. Bioorganic & Medicinal Chemistry Letters. 25: 9-15. PMID 25434000 DOI: 10.1016/J.Bmcl.2014.11.019 |
0.704 |
|
2014 |
Coughlin JM, Rudolf JD, Wendt-Pienkowski E, Wang L, Unsin C, Galm U, Yang D, Tao M, Shen B. BlmB and TlmB provide resistance to the bleomycin family of antitumor antibiotics by N-acetylating metal-free bleomycin, tallysomycin, phleomycin, and zorbamycin. Biochemistry. 53: 6901-9. PMID 25299801 DOI: 10.1021/Bi501121E |
0.746 |
|
2014 |
Hindra, Huang T, Yang D, Rudolf JD, Xie P, Xie G, Teng Q, Lohman JR, Zhu X, Huang Y, Zhao LX, Jiang Y, Duan Y, Shen B. Strain prioritization for natural product discovery by a high-throughput real-time PCR method. Journal of Natural Products. 77: 2296-303. PMID 25238028 DOI: 10.1021/Np5006168 |
0.708 |
|
2014 |
Ge HM, Huang T, Rudolf JD, Lohman JR, Huang SX, Guo X, Shen B. Enediyne polyketide synthases stereoselectively reduce the β-ketoacyl intermediates to β-D-hydroxyacyl intermediates in enediyne core biosynthesis. Organic Letters. 16: 3958-61. PMID 25019332 DOI: 10.1021/Ol501767V |
0.688 |
|
2014 |
Peterson RM, Huang T, Rudolf JD, Smanski MJ, Shen B. Mechanisms of self-resistance in the platensimycin- and platencin-producing Streptomyces platensis MA7327 and MA7339 strains. Chemistry & Biology. 21: 389-97. PMID 24560608 DOI: 10.1016/J.Chembiol.2014.01.005 |
0.727 |
|
2014 |
Xie P, Ma M, Rateb ME, Shaaban KA, Yu Z, Huang SX, Zhao LX, Zhu X, Yan Y, Peterson RM, Lohman JR, Yang D, Yin M, Rudolf JD, Jiang Y, et al. Biosynthetic potential-based strain prioritization for natural product discovery: a showcase for diterpenoid-producing actinomycetes. Journal of Natural Products. 77: 377-87. PMID 24484381 DOI: 10.1021/Np401063S |
0.73 |
|
2013 |
Rudolf JD, Poulter CD. Tyrosine O-prenyltransferase SirD catalyzes S-, C-, and N-prenylations on tyrosine and tryptophan derivatives. Acs Chemical Biology. 8: 2707-14. PMID 24083562 DOI: 10.1021/Cb400691Z |
0.549 |
|
2013 |
Rudolf JD, Wang H, Poulter CD. Correction to multisite prenylation of 4-substituted tryptophans by dimethylallyltryptophan synthase. Journal of the American Chemical Society. 135: 10879. PMID 23848360 DOI: 10.1021/Ja405989J |
0.483 |
|
2013 |
Rudolf JD, Wang H, Poulter CD. Multisite prenylation of 4-substituted tryptophans by dimethylallyltryptophan synthase. Journal of the American Chemical Society. 135: 1895-902. PMID 23301871 DOI: 10.1021/Ja310734N |
0.602 |
|
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