| Year |
Citation |
Score |
| 2024 |
Miniere HJM, Lima EABF, Lorenzo G, Hormuth DA, Ty S, Brock A, Yankeelov TE. A mathematical model for predicting the spatiotemporal response of breast cancer cells treated with doxorubicin. Cancer Biology & Therapy. 25: 2321769. PMID 38411436 DOI: 10.1080/15384047.2024.2321769 |
0.412 |
|
| 2023 |
Howland KK, Brock A. Cellular barcoding tracks heterogeneous clones through selective pressures and phenotypic transitions. Trends in Cancer. PMID 37105856 DOI: 10.1016/j.trecan.2023.03.008 |
0.398 |
|
| 2022 |
Cotner M, Meng S, Jost T, Gardner A, De Santiago C, Brock A. Integration of Quantitative Methods and Mathematical Approaches for the Modeling of Cancer Cell Proliferation Dynamics. American Journal of Physiology. Cell Physiology. PMID 36503241 DOI: 10.1152/ajpcell.00185.2022 |
0.389 |
|
| 2022 |
Yang EY, Howard GR, Brock A, Yankeelov TE, Lorenzo G. Mathematical characterization of population dynamics in breast cancer cells treated with doxorubicin. Frontiers in Molecular Biosciences. 9: 972146. PMID 36172049 DOI: 10.3389/fmolb.2022.972146 |
0.771 |
|
| 2022 |
Howard GR, Jost TA, Yankeelov TE, Brock A. Quantification of long-term doxorubicin response dynamics in breast cancer cell lines to direct treatment schedules. Plos Computational Biology. 18: e1009104. PMID 35358172 DOI: 10.1371/journal.pcbi.1009104 |
0.758 |
|
| 2022 |
Gardner A, Morgan D, Al'Khafaji A, Brock A. Functionalized Lineage Tracing for the Study and Manipulation of Heterogeneous Cell Populations. Methods in Molecular Biology (Clifton, N.J.). 2394: 109-131. PMID 35094325 DOI: 10.1007/978-1-0716-1811-0_8 |
0.778 |
|
| 2021 |
Gutierrez C, Al'Khafaji AM, Brenner E, Johnson KE, Gohil SH, Lin Z, Knisbacher BA, Durrett RE, Li S, Parvin S, Biran A, Zhang W, Rassenti L, Kipps TJ, Livak KJ, ... ... Brock A, et al. Multifunctional barcoding with ClonMapper enables high-resolution study of clonal dynamics during tumor evolution and treatment. Nature Cancer. 2: 758-772. PMID 34939038 DOI: 10.1038/s43018-021-00222-8 |
0.763 |
|
| 2021 |
Morgan D, Jost TA, De Santiago C, Brock A. Applications of high-resolution clone tracking technologies in cancer. Current Opinion in Biomedical Engineering. 19. PMID 34901584 DOI: 10.1016/j.cobme.2021.100317 |
0.343 |
|
| 2021 |
Yang J, Virostko J, Hormuth DA, Liu J, Brock A, Kowalski J, Yankeelov TE. An experimental-mathematical approach to predict tumor cell growth as a function of glucose availability in breast cancer cell lines. Plos One. 16: e0240765. PMID 34255770 DOI: 10.1371/journal.pone.0240765 |
0.31 |
|
| 2020 |
Kazerouni AS, Gadde M, Gardner A, Hormuth DA, Jarrett AM, Johnson KE, Lima EABF, Lorenzo G, Phillips C, Brock A, Yankeelov TE. Integrating Quantitative Assays with Biologically Based Mathematical Modeling for Predictive Oncology. Iscience. 23: 101807. PMID 33299976 DOI: 10.1016/j.isci.2020.101807 |
0.751 |
|
| 2020 |
Johnson KE, Howard GR, Morgan D, Brenner EA, Gardner AL, Durrett RE, Mo W, Al'Khafaji A, Sontag ED, Jarrett AM, Yankeelov TE, Brock A. Integrating transcriptomics and bulk time course data into a mathematical framework to describe and predict therapeutic resistance in cancer. Physical Biology. 18: 016001. PMID 33215611 DOI: 10.1088/1478-3975/Abb09C |
0.737 |
|
| 2020 |
Phillips CM, Lima EABF, Woodall RT, Brock A, Yankeelov TE. A hybrid model of tumor growth and angiogenesis: In silico experiments. Plos One. 15: e0231137. PMID 32275674 DOI: 10.1371/Journal.Pone.0231137 |
0.388 |
|
| 2020 |
Brenner E, Tiwari GR, Kapoor M, Liu Y, Brock A, Mayfield RD. Single cell transcriptome profiling of the human alcohol-dependent brain. Human Molecular Genetics. PMID 32142123 DOI: 10.1093/Hmg/Ddaa038 |
0.682 |
|
| 2019 |
Lele TP, Brock A, Peyton SR. Emerging Concepts and Tools in Cell Mechanomemory. Annals of Biomedical Engineering. PMID 31745676 DOI: 10.1007/S10439-019-02412-Z |
0.362 |
|
| 2019 |
Johnson KE, Howard G, Mo W, Strasser MK, Lima EABF, Huang S, Brock A. Cancer cell population growth kinetics at low densities deviate from the exponential growth model and suggest an Allee effect. Plos Biology. 17: e3000399. PMID 31381560 DOI: 10.1371/Journal.Pbio.3000399 |
0.772 |
|
| 2019 |
Ma KY, Schonnesen AA, Brock A, Van Den Berg C, Eckhardt SG, Liu Z, Jiang N. Single-cell RNA sequencing of lung adenocarcinoma reveals heterogeneity of immune response-related genes. Jci Insight. 4. PMID 30821712 DOI: 10.1172/Jci.Insight.121387 |
0.447 |
|
| 2019 |
Gutierrez C, Al'Khafaji A, Brenner E, Durrett R, Johnson K, Zhang W, Li S, Livak KJ, Neuberg DS, Brock A, Wu CJ. Lineage Tracing in Chronic Lymphocytic Leukemia Reveals Clones with Stable Gene Expression States That Differentially Respond to Therapy Blood. 134: 1229-1229. DOI: 10.1182/Blood-2019-129303 |
0.771 |
|
| 2018 |
Jarrett AM, Lima EABF, Hormuth DA, McKenna IMT, Feng X, Ekrut DA, Resende ACM, Brock A, Yankeelov TE. Mathematical models of tumor cell proliferation: a review of the literature. Expert Review of Anticancer Therapy. PMID 30252552 DOI: 10.1080/14737140.2018.1527689 |
0.47 |
|
| 2018 |
Joyce MH, Lu C, James ER, Hegab R, Allen SC, Suggs LJ, Brock A. Phenotypic Basis for Matrix Stiffness-Dependent Chemoresistance of Breast Cancer Cells to Doxorubicin. Frontiers in Oncology. 8: 337. PMID 30234012 DOI: 10.3389/Fonc.2018.00337 |
0.455 |
|
| 2018 |
Al'Khafaji AM, Deatherage D, Brock A. Control of Lineage-Specific Gene Expression by Functionalized gRNA Barcodes. Acs Synthetic Biology. PMID 30169961 DOI: 10.1021/Acssynbio.8B00105 |
0.781 |
|
| 2018 |
Howard GR, Johnson KE, Rodriguez Ayala A, Yankeelov TE, Brock A. A multi-state model of chemoresistance to characterize phenotypic dynamics in breast cancer. Scientific Reports. 8: 12058. PMID 30104569 DOI: 10.1038/S41598-018-30467-W |
0.777 |
|
| 2018 |
McKenna MT, Weis JA, Brock A, Quaranta V, Yankeelov TE. Precision Medicine with Imprecise Therapy: Computational Modeling for Chemotherapy in Breast Cancer. Translational Oncology. 11: 732-742. PMID 29674173 DOI: 10.1016/J.Tranon.2018.03.009 |
0.416 |
|
| 2017 |
Brock A, Huang S. Precision Oncology: Between Vaguely Right and Precisely Wrong. Cancer Research. PMID 29162615 DOI: 10.1158/0008-5472.Can-17-0448 |
0.613 |
|
| 2017 |
Clark A, Bird NK, Brock A. Intraductal Delivery to the Rabbit Mammary Gland. Journal of Visualized Experiments : Jove. PMID 28362409 DOI: 10.3791/55209 |
0.371 |
|
| 2017 |
Johnson KE, Howard G, Brock A, Yankeelov T. Abstract LB-011: Experimentally derived multi-state model of chemoresistance to characterize phenotypic dynamics in breast cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Lb-011 |
0.757 |
|
| 2017 |
Joyce MH, Allen S, Suggs L, Brock A. Novel Nanomaterials Enable Biomimetic Models of the Tumor Microenvironment Journal of Nanotechnology. 2017: 1-8. DOI: 10.1155/2017/5204163 |
0.75 |
|
| 2015 |
Brock A, Krause S, Ingber DE. Control of cancer formation by intrinsic genetic noise and microenvironmental cues. Nature Reviews. Cancer. 15: 499-509. PMID 26156637 DOI: 10.1038/Nrc3959 |
0.544 |
|
| 2015 |
Davis JD, Ross C, Li H, Brock A. Abstract P2-03-16: Examining 3-dimensional genome architecture and transcriptional profiles using an optimized HiC-seq protocol in breast cancer cells Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P2-03-16 |
0.403 |
|
| 2014 |
Kanapathipillai M, Brock A, Ingber DE. Nanoparticle targeting of anti-cancer drugs that alter intracellular signaling or influence the tumor microenvironment. Advanced Drug Delivery Reviews. 79: 107-18. PMID 24819216 DOI: 10.1016/J.Addr.2014.05.005 |
0.525 |
|
| 2014 |
Brock A, Krause S, Li H, Kowalski M, Goldberg MS, Collins JJ, Ingber DE. Silencing HoxA1 by intraductal injection of siRNA lipidoid nanoparticles prevents mammary tumor progression in mice. Science Translational Medicine. 6: 217ra2. PMID 24382894 DOI: 10.1126/Scitranslmed.3007048 |
0.573 |
|
| 2013 |
Krause S, Brock A, Ingber DE. Intraductal injection for localized drug delivery to the mouse mammary gland. Journal of Visualized Experiments : Jove. PMID 24121742 DOI: 10.3791/50692 |
0.456 |
|
| 2013 |
Pisco AO, Brock A, Zhou J, Moor A, Mojtahedi M, Jackson D, Huang S. Non-Darwinian dynamics in therapy-induced cancer drug resistance. Nature Communications. 4: 2467. PMID 24045430 DOI: 10.1038/Ncomms3467 |
0.607 |
|
| 2013 |
Krause S, Brock A, Goldberg M, Ingber DE. Abstract 2025: Prevention of mammary tumor progression via intraductal injection of nanoparticle-formulated siRNA. Cancer Research. 73: 2025-2025. DOI: 10.1158/1538-7445.Am2013-2025 |
0.537 |
|
| 2012 |
Brock A, Goh HT, Yang B, Lu Y, Li H, Loh YH. Cellular reprogramming: a new technology frontier in pharmaceutical research. Pharmaceutical Research. 29: 35-52. PMID 22068279 DOI: 10.1007/S11095-011-0618-Z |
0.338 |
|
| 2012 |
Brock A. Abstract SY08-02: Gene regulatory network models identify targets for mammary tumor normalization Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Sy08-02 |
0.484 |
|
| 2012 |
Brock A, Li H, Krause S, Kowalski M, Collins JJ, Ingber DE. Abstract 4920: Gene network models identify targets for mammary tumor normalization Cancer Research. 72: 4920-4920. DOI: 10.1158/1538-7445.Am2012-4920 |
0.618 |
|
| 2012 |
Brock A, Krause S, Li H, Kowalski M, Collins J, Ingber D. Abstract P5-05-04: Intraductal delivery of RNAi-based therapeutics to gene targets identified through computational systems modeling Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P5-05-04 |
0.477 |
|
| 2011 |
Krause S, Tobin H, Brock A, Ingber DE. Abstract 520: Local changes in tissue microenvironment regulate mammary tumor progression Cancer Research. 71: 520-520. DOI: 10.1158/1538-7445.Am2011-520 |
0.586 |
|
| 2011 |
Brock A, Li H, Krause S, Collins JJ, Ingber DE. Abstract 4924: Gene network inference models reveal novel key mediators of mammary tumorigenesis Cancer Research. 71: 4924-4924. DOI: 10.1158/1538-7445.Am2011-4924 |
0.556 |
|
| 2009 |
Brock A, Chang H, Huang S. Non-genetic heterogeneity--a mutation-independent driving force for the somatic evolution of tumours. Nature Reviews. Genetics. 10: 336-42. PMID 19337290 DOI: 10.1038/Nrg2556 |
0.68 |
|
| 2005 |
Joy MP, Brock A, Ingber DE, Huang S. High-betweenness proteins in the yeast protein interaction network. Journal of Biomedicine & Biotechnology. 2005: 96-103. PMID 16046814 DOI: 10.1155/Jbb.2005.96 |
0.559 |
|
| 2003 |
Brock A, Chang E, Ho CC, LeDuc P, Jiang X, Whitesides GM, Ingber DE. Geometric determinants of directional cell motility revealed using microcontact printing. Langmuir : the Acs Journal of Surfaces and Colloids. 19: 1611-7. PMID 14674434 DOI: 10.1021/La026394K |
0.655 |
|
| 2003 |
Brock A, Huang S, Ingber DE. Identification of a distinct class of cytoskeleton-associated mRNAs using microarray technology. Bmc Cell Biology. 4: 6. PMID 12848903 DOI: 10.1186/1471-2121-4-6 |
0.625 |
|
| 2002 |
Parker KK, Brock AL, Brangwynne C, Mannix RJ, Wang N, Ostuni E, Geisse NA, Adams JC, Whitesides GM, Ingber DE. Directional control of lamellipodia extension by constraining cell shape and orienting cell tractional forces. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1195-204. PMID 12153987 DOI: 10.1096/Fj.02-0038Com |
0.627 |
|
| 2002 |
Brock A, Huang S. A novel trap for dynamic protein interactions in cytokine signaling. Trends in Biotechnology. 20: 145. PMID 11906744 DOI: 10.1016/S0167-7799(02)01959-5 |
0.462 |
|
| 2002 |
Brock A, Huang S. A bright new tool lights up promoters Trends in Biotechnology. 20: 490. DOI: 10.1016/S0167-7799(02)02099-1 |
0.479 |
|
| 2001 |
Brock A, Huang S. Proteomics in context Trends in Biotechnology. 19: 435. DOI: 10.1016/S0167-7799(01)01863-7 |
0.504 |
|
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