Ling Qi, Ph.D. - Publications

Affiliations: 
2002 University of Maryland, Baltimore County, Baltimore, MD, United States 
 2016- University of Michigan Medical School, Ann Arbor, MI, United States 
Area:
Immunology, Protein degradation, Endoplasmic reticulum, beta-cells inflamation
Website:
https://sites.google.com/a/umich.edu/ling-qi-lab/

88 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Mao H, Kim GH, Qi L. SEL1L-HRD1 ER-associated degradation regulates leptin receptor maturation and signaling in POMC neurons in diet-induced obesity. Research Square. PMID 38260335 DOI: 10.21203/rs.3.rs-3768472/v1  0.307
2023 Abdon B, Liang Y, da Luz Scheffer D, Torres M, Shrestha N, Reinert RB, Lu Y, Pederson B, Bugarin-Lapuz A, Kersten S, Qi L. Muscle specific ER-associated degradation maintains postnatal muscle hypertrophy and systemic energy metabolism. Jci Insight. PMID 37535424 DOI: 10.1172/jci.insight.170387  0.724
2023 Zhang X, Young C, Liao XH, Refetoff S, Torres M, Tomer Y, Stefan-Lifshitz M, Zhang H, Larkin D, Fang D, Qi L, Arvan P. Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland. Jci Insight. 8. PMID 37345654 DOI: 10.1172/jci.insight.169937  0.704
2023 Lin LL, Wei X, Wang HH, Pederson B, Torres M, Lu Y, Li ZJ, Liu X, Mao H, Wang H, Zhao Z, Sun S, Qi L. SEL1L-HRD1 interaction is prerequisite for the formation of a functional HRD1 ERAD complex. Biorxiv : the Preprint Server For Biology. PMID 37333389 DOI: 10.1101/2023.04.13.536796  0.679
2023 Wu SA, Shen C, Wei X, Zhang X, Wang S, Chen X, Torres M, Lu Y, Lin LL, Wang HH, Hunter AH, Fang D, Sun S, Ivanova MI, Lin Y, ... Qi L, et al. The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes. Nature Communications. 14: 3132. PMID 37253728 DOI: 10.1038/s41467-023-38690-4  0.715
2023 Ji Y, Luo Y, Wu Y, Sun Y, Zhao L, Xue Z, Sun M, Wei X, He Z, Wu SA, Lin LL, Lu Y, Chang L, Chen F, Chen S, ... ... Qi L, et al. SEL1L-HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool. Nature Cell Biology. PMID 37142791 DOI: 10.1038/s41556-023-01138-4  0.556
2022 Shrestha N, Torres M, Zhang J, Lu Y, Haataja L, Reinert RB, Knupp J, Chen YJ, Parlakgul G, Arruda AP, Tsai B, Arvan P, Qi L. Integration of ER protein quality control mechanisms defines β-cell function and ER architecture. The Journal of Clinical Investigation. PMID 36346671 DOI: 10.1172/JCI163584  0.767
2021 Yoshida S, Wei X, Zhang G, O'Connor CL, Torres M, Zhou Z, Lin L, Menon R, Xu X, Zheng W, Xiong Y, Otto EA, Tang CA, Hua R, Verma R, ... ... Qi L, et al. Endoplasmic reticulum-associated degradation is required for nephrin maturation and kidney glomerular filtration function. The Journal of Clinical Investigation. PMID 33591954 DOI: 10.1172/JCI143988  0.758
2020 Liu L, Inoki A, Fan K, Mao F, Shi G, Jin X, Zhao M, Ney G, Jones MA, Sun S, Dou Y, Inoki K, Qi L, Li Q. ER associated degradation preserves hematopoietic stem cell quiescence and self-renewal by restricting mTOR activity. Blood. PMID 33150381 DOI: 10.1182/blood.2020007975  0.654
2020 Xu L, Liu X, Peng F, Zhang W, Zheng L, Ding Y, Gu T, Lv K, Wang J, Ortinau L, Hu T, Shi X, Shi G, Shang G, Sun S, ... ... Qi L, et al. Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions. Nature Cell Biology. PMID 32958856 DOI: 10.1038/S41556-020-00581-X  0.672
2020 Zhao XY, Zhou L, Chen Z, Ji Y, Peng X, Qi L, Li S, Lin JD. The obesity-induced adipokine sST2 exacerbates adipose T and ILC2 depletion and promotes insulin resistance. Science Advances. 6: eaay6191. PMID 32426492 DOI: 10.1126/Sciadv.Aay6191  0.334
2020 Shrestha N, Reinert RB, Qi L. Endoplasmic Reticulum Protein Quality Control in β Cells. Seminars in Cell & Developmental Biology. PMID 32402517 DOI: 10.1016/J.Semcdb.2020.04.006  0.614
2020 Zhou Z, Torres M, Sha H, Halbrook CJ, Van den Bergh F, Reinert RB, Yamada T, Wang S, Luo Y, Hunter AH, Wang C, Sanderson TH, Liu M, Taylor A, Sesaki H, ... ... Qi L, et al. Endoplasmic reticulum-associated degradation regulates mitochondrial dynamics in brown adipocytes. Science (New York, N.Y.). PMID 32193362 DOI: 10.1126/Science.Aay2494  0.767
2020 Shrestha N, Liu T, Ji Y, Reinert R, Torres M, Li X, Zhang M, Tang CA, Hu CA, Liu C, Naji A, Liu M, Lin JD, Kersten S, Arvan P, ... Qi L, et al. Sel1L-Hrd1 ER-associated degradation maintains β-cell identity via TGFβ signaling. The Journal of Clinical Investigation. PMID 32182217 DOI: 10.1172/Jci134874  0.752
2020 Bagchi P, Torres M, Qi L, Tsai B. Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry. Nature Communications. 11: 1127. PMID 32111841 DOI: 10.1038/S41467-020-14967-W  0.7
2020 Young KZ, Lee SJ, Zhang X, Cartee NMP, Torres M, Keep SG, Gabbireddy SR, Fontana JL, Qi L, Wang MM. NOTCH3 is non-enzymatically fragmented in inherited cerebral small-vessel disease. The Journal of Biological Chemistry. PMID 31901894 DOI: 10.1074/Jbc.Ra119.007724  0.676
2020 Shrestha N, Reinert RB, Arvan P, Qi L. 49-OR: Synergistic Effect of ERAD and Autophagy in Preventing Proinsulin Aggregation and Promoting Beta-Cell Survival Diabetes. 69. DOI: 10.2337/Db20-49-Or  0.525
2020 Reinert RB, Cui X, Shrestha N, Qi L. 323-OR: Synergism between Protein Quality Control Pathways to Maintain Alpha-Cell Mass and Function Diabetes. 69. DOI: 10.2337/Db20-323-Or  0.63
2020 Torres M, Zhou Z, Qi L, Wang S. 1959-P: Sel1l-Hrd1 ER-Associated Degradation (ERAD) Controls Mitochondrial Dynamics, ER-Mitochondrial Dynamics, and ER-Mitochondria Contacts in Brown Adipocytes Diabetes. 69. DOI: 10.2337/Db20-1959-P  0.753
2020 Wu S, Torres M, Qi L. 1931-P: New Insights Into Lipoprotein Lipase Maturation in the ER Diabetes. 69. DOI: 10.2337/Db20-1931-P  0.732
2020 Shi G, Pan X, Wang H, Arvan P, Qi L. 1893-P: The Integrative Role of ER Protein Quality Control Pathways (ERQC) in Prohormone Maturation Diabetes. 69. DOI: 10.2337/Db20-1893-P  0.718
2019 Li X, Itani OA, Haataja L, Dumas KJ, Yang J, Cha J, Flibotte S, Shih HJ, Delaney CE, Xu J, Qi L, Arvan P, Liu M, Hu PJ. Requirement for translocon-associated protein (TRAP) α in insulin biogenesis. Science Advances. 5: eaax0292. PMID 31840061 DOI: 10.1126/Sciadv.Aax0292  0.378
2019 Bhattacharya A, Qi L. ER-associated degradation in health and disease - from substrate to organism. Journal of Cell Science. 132. PMID 31792042 DOI: 10.1242/Jcs.232850  0.392
2019 Shen H, Ji Y, Xiong Y, Kim H, Zhong X, Jin MG, Shah YM, Omary MB, Liu Y, Qi L, Rui L. Medullary thymic epithelial NF-kB-inducing kinase (NIK)/IKKα pathway shapes autoimmunity and liver and lung homeostasis in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 31481626 DOI: 10.1073/Pnas.1901056116  0.545
2019 Xiong X, Kuang H, Ansari S, Liu T, Gong J, Wang S, Zhao XY, Ji Y, Li C, Guo L, Zhou L, Chen Z, Leon-Mimila P, Chung MT, Kurabayashi K, ... ... Qi L, et al. Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis. Molecular Cell. 75: 644-660.e5. PMID 31398325 DOI: 10.1016/J.Molcel.2019.07.028  0.314
2019 Ji Y, Sun S, Shrestha N, Darragh LB, Shirakawa J, Xing Y, He Y, Carboneau BA, Kim H, An D, Ma M, Oberholzer J, Soleimanpour SA, Gannon M, Liu C, ... ... Qi L, et al. Toll-like receptors TLR2 and TLR4 block the replication of pancreatic β cells in diet-induced obesity. Nature Immunology. PMID 31110312 DOI: 10.1038/S41590-019-0396-Z  0.676
2019 Cho H, Stanzione F, Oak A, Kim GH, Yerneni S, Qi L, Sum AK, Chan C. Intrinsic Structural Features of the Human IRE1α Transmembrane Domain Sense Membrane Lipid Saturation. Cell Reports. 27: 307-320.e5. PMID 30943411 DOI: 10.1016/J.Celrep.2019.03.017  0.57
2019 Reinert RB, Shrestha N, Ji Y, Qi L. 2197-P: SEL1L-HRD1 Endoplasmic Reticulum-Associated Degradation Is Required for Maintaining Glucagon Production in Pancreatic Alpha Cells Diabetes. 68. DOI: 10.2337/Db19-2197-P  0.645
2019 SHRESTHA N, LI X, JI Y, REINERT RB, ARVAN P, QI L. 2166-P: Sel1L-Hrd1 ERAD Is a Key Regulator of Beta-Cell Function and Identity Diabetes. 68: 2166-P. DOI: 10.2337/Db19-2166-P  0.64
2019 Ji Y, Sun S, Qi L. 2142-P: Toll-Like Receptors 2 and 4 Act as Brakes to Regulate Adaptive ß-Cell Mass Expansion in Diet-Induced Obesity Diabetes. 68. DOI: 10.2337/Db19-2142-P  0.363
2019 Zhou Z, Torres M, Qi L. 141-OR: Regulation of Mitochondrial Dynamics in Brown Adipocytes by the Endoplasmic Reticulum-Associated Degradation Diabetes. 68. DOI: 10.2337/Db19-141-Or  0.772
2018 Bhattacharya A, Sun S, Wang H, Liu M, Long Q, Yin L, Kersten S, Zhang K, Qi L. Hepatic Sel1L-Hrd1 ER-associated degradation (ERAD) manages FGF21 levels and systemic metabolism via CREBH. The Embo Journal. PMID 30389665 DOI: 10.15252/Embj.201899277  0.376
2018 Schultz ML, Krus KL, Kaushik S, Dang D, Chopra R, Qi L, Shakkottai VG, Cuervo AM, Lieberman AP. Coordinate regulation of mutant NPC1 degradation by selective ER autophagy and MARCH6-dependent ERAD. Nature Communications. 9: 3671. PMID 30202070 DOI: 10.1038/S41467-018-06115-2  0.318
2018 Hwang J, Qi L. Quality Control in the Endoplasmic Reticulum: Crosstalk between ERAD and UPR pathways. Trends in Biochemical Sciences. 43: 593-605. PMID 30056836 DOI: 10.1016/J.Tibs.2018.06.005  0.418
2018 Urra H, Henriquez DR, Cánovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, Molina E, Hazari YM, Limia CM, Alvarez-Rojas S, Figueroa R, Vidal RL, Rodriguez DA, Rivera CA, Court FA, ... ... Qi L, et al. IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A. Nature Cell Biology. PMID 30013108 DOI: 10.1038/S41556-018-0141-0  0.4
2018 Kim GH, Shi G, Somlo DR, Haataja L, Song S, Long Q, Nillni EA, Low MJ, Arvan P, Myers MG, Qi L. Hypothalamic ER-associated degradation regulates POMC maturation, feeding, and age-associated obesity. The Journal of Clinical Investigation. PMID 29457782 DOI: 10.1172/Jci96420  0.763
2018 Arunagiri A, Haataja L, Cunningham CN, Shrestha N, Tsai B, Qi L, Liu M, Arvan P. Misfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes. Annals of the New York Academy of Sciences. PMID 29377149 DOI: 10.1111/Nyas.13531  0.592
2017 Shi G, Somlo D, Kim GH, Prescianotto-Baschong C, Sun S, Beuret N, Long Q, Rutishauser J, Arvan P, Spiess M, Qi L. ER-associated degradation is required for vasopressin prohormone processing and systemic water homeostasis. The Journal of Clinical Investigation. PMID 28920920 DOI: 10.1172/Jci94771  0.767
2017 Oteng AB, Bhattacharya A, Brodesser S, Qi L, Tan NS, Kersten S. Feeding Angptl4-/- mice trans fat promotes foam cell formation in mesenteric lymph nodes without leading to ascites. Journal of Lipid Research. PMID 28412693 DOI: 10.1194/Jlr.M074278  0.304
2017 Dijk W, Mattijssen F, de la Rosa Rodriguez M, Loza Valdes A, Loft A, Mandrup S, Kalkhoven E, Qi L, Borst JW, Kersten S. Hypoxia-inducible lipid droplet-associated (HILPDA) is not a direct physiological regulator of lipolysis in adipose tissue. Endocrinology. PMID 28323980 DOI: 10.1210/En.2016-1809  0.357
2017 Qi L, Tsai B, Arvan P. New Insights into the Physiological Role of Endoplasmic Reticulum-Associated Degradation. Trends in Cell Biology. PMID 28131647 DOI: 10.1016/J.Tcb.2016.12.002  0.474
2017 Zhu S, Liu H, Sha H, Qi L, Gao DS, Zhang W. PERK and XBP1 differentially regulate CXCL10 and CCL2 production. Experimental Eye Research. PMID 28065589 DOI: 10.1016/J.Exer.2017.01.002  0.375
2016 Ji Y, Kim H, Yang L, Sha H, Roman CA, Long Q, Qi L. The Sel1L-Hrd1 Endoplasmic Reticulum-Associated Degradation Complex Manages a Key Checkpoint in B Cell Development. Cell Reports. PMID 27568564 DOI: 10.1016/J.Celrep.2016.08.003  0.582
2015 Sun S, Lourie R, Cohen SB, Ji Y, Goodrich JK, Poole AC, Ley RE, Denkers EY, McGuckin MA, Long Q, Duhamel GE, Simpson KW, Qi L. Epithelial Sel1L is required for the maintenance of intestinal homeostasis. Molecular Biology of the Cell. PMID 26631554 DOI: 10.1091/Mbc.E15-10-0724  0.378
2015 Sun S, Shi G, Sha H, Ji Y, Han X, Shu X, Ma H, Inoue T, Gao B, Kim H, Bu P, Guber RD, Shen X, Lee AH, Iwawaki T, ... ... Qi L, et al. IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation. Nature Cell Biology. PMID 26551274 DOI: 10.1038/Ncb3266  0.77
2015 Ma H, Dang Y, Wu Y, Jia G, Anaya E, Zhang J, Abraham S, Choi JG, Shi G, Qi L, Manjunath N, Wu H. A CRISPR-Based Screen Identifies Genes Essential for West-Nile-Virus-Induced Cell Death. Cell Reports. PMID 26190106 DOI: 10.1016/J.Celrep.2015.06.049  0.653
2015 Kim H, Bhattacharya A, Qi L. Endoplasmic reticulum quality control in cancer: Friend or foe. Seminars in Cancer Biology. PMID 25794824 DOI: 10.1016/J.Semcancer.2015.02.003  0.58
2014 Sha H, Sun S, Francisco AB, Ehrhardt N, Xue Z, Liu L, Lawrence P, Mattijssen F, Guber RD, Panhwar MS, Brenna JT, Shi H, Xue B, Kersten S, Bensadoun A, ... ... Qi L, et al. The ER-associated degradation adaptor protein Sel1L regulates LPL secretion and lipid metabolism. Cell Metabolism. 20: 458-70. PMID 25066055 DOI: 10.1016/J.Cmet.2014.06.015  0.486
2014 Ji Y, Sun S, Goodrich JK, Kim H, Poole AC, Duhamel GE, Ley RE, Qi L. Diet-induced alterations in gut microflora contribute to lethal pulmonary damage in TLR2/TLR4-deficient mice. Cell Reports. 8: 137-49. PMID 24953658 DOI: 10.1016/J.Celrep.2014.05.040  0.532
2014 Mattijssen F, Georgiadi A, Andasarie T, Szalowska E, Zota A, Krones-Herzig A, Heier C, Ratman D, De Bosscher K, Qi L, Zechner R, Herzig S, Kersten S. Hypoxia-inducible lipid droplet-associated (HILPDA) is a novel peroxisome proliferator-activated receptor (PPAR) target involved in hepatic triglyceride secretion. The Journal of Biological Chemistry. 289: 19279-93. PMID 24876382 DOI: 10.1074/Jbc.M114.570044  0.338
2014 Qi L. Tipping the balance in metabolic regulation: regulating regulatory T cells by costimulation. Diabetes. 63: 1179-81. PMID 24651799 DOI: 10.2337/Db13-1915  0.316
2014 Sun S, Shi G, Han X, Francisco AB, Ji Y, Mendonça N, Liu X, Locasale JW, Simpson KW, Duhamel GE, Kersten S, Yates JR, Long Q, Qi L. Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival. Proceedings of the National Academy of Sciences of the United States of America. 111: E582-91. PMID 24453213 DOI: 10.1073/Pnas.1318114111  0.731
2014 Sha H, Yang L, Liu M, Xia S, Liu Y, Liu F, Kersten S, Qi L. Adipocyte spliced form of X-box-binding protein 1 promotes adiponectin multimerization and systemic glucose homeostasis. Diabetes. 63: 867-79. PMID 24241534 DOI: 10.2337/Db13-1067  0.409
2014 Sun S, Shi G, Han X, Francisco AB, Ji Y, Mendonça N, Liu X, Locasale JW, Simpson KW, Duhamel GE, Kersten S, Yates JR, Long Q, Qi L. Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival (Proceedings of the National Academy of Sciences of the United States of America (2014) 111, 5, (E582-E591) doi:10.1073/pnas.1318114111) Proceedings of the National Academy of Sciences of the United States of America. 111: 6115. DOI: 10.1073/Pnas.1405563111  0.639
2013 Iwata TN, Cowley TJ, Sloma M, Ji Y, Kim H, Qi L, Lee SS. The transcriptional co-regulator HCF-1 is required for INS-1 β-cell glucose-stimulated insulin secretion. Plos One. 8: e78841. PMID 24250814 DOI: 10.1371/Journal.Pone.0078841  0.576
2013 Yang L, Sha H, Davisson RL, Qi L. Phenformin activates the unfolded protein response in an AMP-activated protein kinase (AMPK)-dependent manner. The Journal of Biological Chemistry. 288: 13631-8. PMID 23548904 DOI: 10.1074/Jbc.M113.462762  0.329
2013 Duplan E, Giaime E, Viotti J, Sévalle J, Corti O, Brice A, Ariga H, Qi L, Checler F, Alves da Costa C. ER-stress-associated functional link between Parkin and DJ-1 via a transcriptional cascade involving the tumor suppressor p53 and the spliced X-box binding protein XBP-1. Journal of Cell Science. 126: 2124-33. PMID 23447676 DOI: 10.1242/Jcs.127340  0.38
2012 He Y, Beatty A, Han X, Ji Y, Ma X, Adelstein RS, Yates JR, Kemphues K, Qi L. Nonmuscle myosin IIB links cytoskeleton to IRE1α signaling during ER stress. Developmental Cell. 23: 1141-52. PMID 23237951 DOI: 10.1016/J.Devcel.2012.11.006  0.381
2012 Yang Z, Wang X, He Y, Qi L, Yu L, Xue B, Shi H. The full capacity of AICAR to reduce obesity-induced inflammation and insulin resistance requires myeloid SIRT1. Plos One. 7: e49935. PMID 23183898 DOI: 10.1371/Journal.Pone.0049935  0.322
2012 Ji Y, Sun S, Xia S, Yang L, Li X, Qi L. Short term high fat diet challenge promotes alternative macrophage polarization in adipose tissue via natural killer T cells and interleukin-4. The Journal of Biological Chemistry. 287: 24378-86. PMID 22645141 DOI: 10.1074/Jbc.M112.371807  0.334
2012 Sun S, Xia S, Ji Y, Kersten S, Qi L. The ATP-P2X7 signaling axis is dispensable for obesity-associated inflammasome activation in adipose tissue. Diabetes. 61: 1471-8. PMID 22415881 DOI: 10.2337/Db11-1389  0.32
2012 Sun S, Ji Y, Kersten S, Qi L. Mechanisms of inflammatory responses in obese adipose tissue. Annual Review of Nutrition. 32: 261-86. PMID 22404118 DOI: 10.1146/Annurev-Nutr-071811-150623  0.317
2012 Ji Y, Sun S, Xu A, Bhargava P, Yang L, Lam KS, Gao B, Lee CH, Kersten S, Qi L. Activation of natural killer T cells promotes M2 Macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesity. The Journal of Biological Chemistry. 287: 13561-71. PMID 22396530 DOI: 10.1074/Jbc.M112.350066  0.364
2011 Mao T, Shao M, Qiu Y, Huang J, Zhang Y, Song B, Wang Q, Jiang L, Liu Y, Han JD, Cao P, Li J, Gao X, Rui L, Qi L, et al. PKA phosphorylation couples hepatic inositol-requiring enzyme 1alpha to glucagon signaling in glucose metabolism. Proceedings of the National Academy of Sciences of the United States of America. 108: 15852-7. PMID 21911379 DOI: 10.1073/Pnas.1107394108  0.364
2011 Xue Z, He Y, Ye K, Gu Z, Mao Y, Qi L. A conserved structural determinant located at the interdomain region of mammalian inositol-requiring enzyme 1alpha. The Journal of Biological Chemistry. 286: 30859-66. PMID 21757700 DOI: 10.1074/Jbc.M111.273714  0.319
2011 Sha H, He Y, Yang L, Qi L. Stressed out about obesity: IRE1α-XBP1 in metabolic disorders. Trends in Endocrinology and Metabolism: Tem. 22: 374-81. PMID 21703863 DOI: 10.1016/J.Tem.2011.05.002  0.365
2011 Xia S, Sha H, Yang L, Ji Y, Ostrand-Rosenberg S, Qi L. Gr-1+ CD11b+ myeloid-derived suppressor cells suppress inflammation and promote insulin sensitivity in obesity. The Journal of Biological Chemistry. 286: 23591-9. PMID 21592961 DOI: 10.1074/Jbc.M111.237123  0.589
2011 Francisco AB, Singh R, Sha H, Yan X, Qi L, Lei X, Long Q. Haploid insufficiency of suppressor enhancer Lin12 1-like (SEL1L) protein predisposes mice to high fat diet-induced hyperglycemia. The Journal of Biological Chemistry. 286: 22275-82. PMID 21536682 DOI: 10.1074/Jbc.M111.239418  0.439
2011 Qi L, Yang L, Chen H. Detecting and quantitating physiological endoplasmic reticulum stress. Methods in Enzymology. 490: 137-46. PMID 21266248 DOI: 10.1016/B978-0-12-385114-7.00008-8  0.368
2010 Lichtenstein L, Mattijssen F, de Wit NJ, Georgiadi A, Hooiveld GJ, van der Meer R, He Y, Qi L, Köster A, Tamsma JT, Tan NS, Müller M, Kersten S. Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophages. Cell Metabolism. 12: 580-92. PMID 21109191 DOI: 10.1016/J.Cmet.2010.11.002  0.325
2010 He Y, Sun S, Sha H, Liu Z, Yang L, Xue Z, Chen H, Qi L. Emerging roles for XBP1, a sUPeR transcription factor. Gene Expression. 15: 13-25. PMID 21061914 DOI: 10.3727/105221610X12819686555051  0.382
2010 Yang L, Xue Z, He Y, Sun S, Chen H, Qi L. A Phos-tag-based approach reveals the extent of physiological endoplasmic reticulum stress. Plos One. 5: e11621. PMID 20661282 DOI: 10.1371/Journal.Pone.0011621  0.377
2010 Zeng L, Liu YP, Sha H, Chen H, Qi L, Smith JA. XBP-1 couples endoplasmic reticulum stress to augmented IFN-beta induction via a cis-acting enhancer in macrophages. Journal of Immunology (Baltimore, Md. : 1950). 185: 2324-30. PMID 20660350 DOI: 10.4049/Jimmunol.0903052  0.346
2010 Liew CW, Bochenski J, Kawamori D, Hu J, Leech CA, Wanic K, Malecki M, Warram JH, Qi L, Krolewski AS, Kulkarni RN. The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells. The Journal of Clinical Investigation. 120: 2876-88. PMID 20592469 DOI: 10.1172/Jci36849  0.359
2010 Zmuda EJ, Qi L, Zhu MX, Mirmira RG, Montminy MR, Hai T. The roles of ATF3, an adaptive-response gene, in high-fat-diet-induced diabetes and pancreatic beta-cell dysfunction. Molecular Endocrinology (Baltimore, Md.). 24: 1423-33. PMID 20519332 DOI: 10.1210/Me.2009-0463  0.62
2010 Chen H, Qi L. SUMO modification regulates the transcriptional activity of XBP1. The Biochemical Journal. 429: 95-102. PMID 20408817 DOI: 10.1042/Bj20100193  0.395
2010 Francisco AB, Singh R, Li S, Vani AK, Yang L, Munroe RJ, Diaferia G, Cardano M, Biunno I, Qi L, Schimenti JC, Long Q. Deficiency of suppressor enhancer Lin12 1 like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic lethality. The Journal of Biological Chemistry. 285: 13694-703. PMID 20197277 DOI: 10.1074/Jbc.M109.085340  0.462
2009 Sha H, He Y, Chen H, Wang C, Zenno A, Shi H, Yang X, Zhang X, Qi L. The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis. Cell Metabolism. 9: 556-64. PMID 19490910 DOI: 10.1016/J.Cmet.2009.04.009  0.391
2009 Qi L, Saberi M, Zmuda E, Wang Y, Altarejos J, Zhang X, Dentin R, Hedrick S, Bandyopadhyay G, Hai T, Olefsky J, Montminy M. Adipocyte CREB promotes insulin resistance in obesity. Cell Metabolism. 9: 277-86. PMID 19254572 DOI: 10.1016/J.Cmet.2009.01.006  0.612
2006 Qi L, Heredia JE, Altarejos JY, Screaton R, Goebel N, Niessen S, Macleod IX, Liew CW, Kulkarni RN, Bain J, Newgard C, Nelson M, Evans RM, Yates J, Montminy M. TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism. Science (New York, N.Y.). 312: 1763-6. PMID 16794074 DOI: 10.1126/Science.1123374  0.776
2005 Koo SH, Flechner L, Qi L, Zhang X, Screaton RA, Jeffries S, Hedrick S, Xu W, Boussouar F, Brindle P, Takemori H, Montminy M. The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. Nature. 437: 1109-11. PMID 16148943 DOI: 10.1038/Nature03967  0.761
2005 Qi L, Strong MA, Karim BO, Huso DL, Greider CW. Telomere fusion to chromosome breaks reduces oncogenic translocations and tumour formation. Nature Cell Biology. 7: 706-11. PMID 15965466 DOI: 10.1038/Ncb1276  0.584
2004 Dolan BP, Phelan TP, Ilkovitch D, Qi L, Wade WF, Laufer TM, Ostrand-Rosenberg S. Invariant chain and the MHC class II cytoplasmic domains regulate localization of MHC class II molecules to lipid rafts in tumor cell-based vaccines. Journal of Immunology (Baltimore, Md. : 1950). 172: 907-14. PMID 14707062 DOI: 10.4049/Jimmunol.172.2.907  0.531
2003 Qi L, Strong MA, Karim BO, Armanios M, Huso DL, Greider CW. Short telomeres and ataxia-telangiectasia mutated deficiency cooperatively increase telomere dysfunction and suppress tumorigenesis. Cancer Research. 63: 8188-96. PMID 14678974  0.71
2001 Qi L, Ostrand-Rosenberg S. H2-O inhibits presentation of bacterial superantigens, but not endogenous self antigens. Journal of Immunology (Baltimore, Md. : 1950). 167: 1371-8. PMID 11466355 DOI: 10.4049/Jimmunol.167.3.1371  0.525
2000 Qi L, Ostrand-Rosenberg S. MHC class II presentation of endogenous tumor antigen by cellular vaccines depends on the endocytic pathway but not H2-M. Traffic (Copenhagen, Denmark). 1: 152-60. PMID 11208095 DOI: 10.1034/J.1600-0854.2000.010207.X  0.533
2000 Qi L, Rojas JM, Ostrand-Rosenberg S. Tumor cells present MHC class II-restricted nuclear and mitochondrial antigens and are the predominant antigen presenting cells in vivo. Journal of Immunology (Baltimore, Md. : 1950). 165: 5451-61. PMID 11067897 DOI: 10.4049/Jimmunol.165.10.5451  0.549
1999 Ostrand-Rosenberg S, Pulaski BA, Clements VK, Qi L, Pipeling MR, Hanyok LA. Cell-based vaccines for the stimulation of immunity to metastatic cancers. Immunological Reviews. 170: 101-14. PMID 10566145 DOI: 10.1111/J.1600-065X.1999.Tb01332.X  0.531
Show low-probability matches.