James R. Faeder - Publications

Affiliations: 
1998-1999 Department of Computational Biology University of Pittsburgh School of Medicine, Pittsburgh, PA, United States 

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Keating SM, Waltemath D, König M, Zhang F, Dräger A, Chaouiya C, Bergmann FT, Finney A, Gillespie CS, Helikar T, Hoops S, Malik-Sheriff RS, Moodie SL, Moraru II, Myers CJ, ... ... Faeder JR, et al. SBML Level 3: an extensible format for the exchange and reuse of biological models. Molecular Systems Biology. 16: e9110. PMID 32845085 DOI: 10.15252/Msb.20199110  0.396
2020 Zhang F, Smith LP, Blinov ML, Faeder J, Hlavacek WS, Juan Tapia J, Keating SM, Rodriguez N, Dräger A, Harris LA, Finney A, Hu B, Hucka M, Meier-Schellersheim M. Systems biology markup language (SBML) level 3 package: multistate, multicomponent and multicompartment species, version 1, release 2. Journal of Integrative Bioinformatics. PMID 32628633 DOI: 10.1515/Jib-2020-0015  0.352
2020 Gupta S, Lee REC, Faeder JR. Parallel Tempering with Lasso for model reduction in systems biology. Plos Computational Biology. 16: e1007669. PMID 32150537 DOI: 10.1371/Journal.Pcbi.1007669  0.392
2019 Tapia JJ, Saglam AS, Czech J, Kuczewski R, Bartol TM, Sejnowski TJ, Faeder JR. MCell-R: A Particle-Resolution Network-Free Spatial Modeling Framework. Methods in Molecular Biology (Clifton, N.J.). 1945: 203-229. PMID 30945248 DOI: 10.1007/978-1-4939-9102-0_9  0.391
2017 Sekar JAP, Tapia JJ, Faeder JR. Automated visualization of rule-based models. Plos Computational Biology. 13: e1005857. PMID 29131816 DOI: 10.1371/Journal.Pcbi.1005857  0.355
2017 Kaya C, Cheng MH, Block ER, Sorkin A, Faeder JR, Bahar I. Effect of Spatial Complexity on Dopaminergic Signaling Revealed from Multiscale Simulations Biophysical Journal. 112: 135a. DOI: 10.1016/J.Bpj.2016.11.751  0.323
2016 Morel PA, Lee RE, Faeder JR. Demystifying the cytokine network: Mathematical models point the way. Cytokine. PMID 27919524 DOI: 10.1016/J.Cyto.2016.11.013  0.371
2016 Harris LA, Hogg JS, Tapia JJ, Sekar JA, Gupta S, Korsunsky I, Arora A, Barua D, Sheehan RP, Faeder JR. BioNetGen 2.2: Advances in Rule-Based Modeling. Bioinformatics (Oxford, England). PMID 27402907 DOI: 10.1093/Bioinformatics/Btw469  0.371
2016 Faeder JR, Morel PA. Reductionism Is Dead: Long Live Reductionism! Systems Modeling Needs Reductionist Experiments. Biophysical Journal. 110: 1681-3. PMID 27119628 DOI: 10.1016/J.Bpj.2016.03.025  0.367
2016 Donovan RM, Tapia JJ, Sullivan DP, Faeder JR, Murphy RF, Dittrich M, Zuckerman DM. Unbiased Rare Event Sampling in Spatial Stochastic Systems Biology Models Using a Weighted Ensemble of Trajectories. Plos Computational Biology. 12: e1004611. PMID 26845334 DOI: 10.1371/Journal.Pcbi.1004611  0.333
2015 Chylek LA, Harris LA, Faeder JR, Hlavacek WS. Modeling for (physical) biologists: an introduction to the rule-based approach. Physical Biology. 12: 045007. PMID 26178138 DOI: 10.1088/1478-3975/12/4/045007  0.359
2014 Wenskovitch JE, Harris LA, Tapia JJ, Faeder JR, Marai GE. MOSBIE: a tool for comparison and analysis of rule-based biochemical models. Bmc Bioinformatics. 15: 316. PMID 25253680 DOI: 10.1186/1471-2105-15-316  0.374
2014 Hogg JS, Harris LA, Stover LJ, Nair NS, Faeder JR. Exact hybrid particle/population simulation of rule-based models of biochemical systems. Plos Computational Biology. 10: e1003544. PMID 24699269 DOI: 10.1371/Journal.Pcbi.1003544  0.364
2014 Chylek LA, Harris LA, Tung CS, Faeder JR, Lopez CF, Hlavacek WS. Rule-based modeling: a computational approach for studying biomolecular site dynamics in cell signaling systems. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 6: 13-36. PMID 24123887 DOI: 10.1002/Wsbm.1245  0.407
2013 Donovan RM, Sedgewick AJ, Faeder JR, Zuckerman DM. Efficient stochastic simulation of chemical kinetics networks using a weighted ensemble of trajectories. The Journal of Chemical Physics. 139: 115105. PMID 24070313 DOI: 10.1063/1.4821167  0.345
2013 Sheehan RP, Garg A, Gaffen SL, Faeder JR. 236 Cytokine. 63: 299. DOI: 10.1016/J.Cyto.2013.06.239  0.369
2012 Sekar JA, Faeder JR. Rule-based modeling of signal transduction: a primer. Methods in Molecular Biology (Clifton, N.J.). 880: 139-218. PMID 23361986 DOI: 10.1007/978-1-61779-833-7_9  0.4
2012 Smith AM, Xu W, Sun Y, Faeder JR, Marai GE. RuleBender: integrated modeling, simulation and visualization for rule-based intracellular biochemistry. Bmc Bioinformatics. 13: S3. PMID 22607382 DOI: 10.1186/1471-2105-13-S8-S3  0.351
2011 Horton AA, Wang B, Camp L, Price MS, Arshi A, Nagy M, Nadler SA, Faeder JR, Luckhart S. The mitogen-activated protein kinome from Anopheles gambiae: identification, phylogeny and functional characterization of the ERK, JNK and p38 MAP kinases. Bmc Genomics. 12: 574. PMID 22111877 DOI: 10.1186/1471-2164-12-574  0.307
2011 Faeder JR. Toward a comprehensive language for biological systems. Bmc Biology. 9: 68. PMID 22005092 DOI: 10.1186/1741-7007-9-68  0.356
2011 Chylek LA, Hu B, Blinov ML, Emonet T, Faeder JR, Goldstein B, Gutenkunst RN, Haugh JM, Lipniacki T, Posner RG, Yang J, Hlavacek WS. Guidelines for visualizing and annotating rule-based models. Molecular Biosystems. 7: 2779-95. PMID 21647530 DOI: 10.1039/C1Mb05077J  0.379
2011 Xu W, Smith AM, Faeder JR, Marai GE. RuleBender: a visual interface for rule-based modeling. Bioinformatics (Oxford, England). 27: 1721-2. PMID 21493655 DOI: 10.1093/Bioinformatics/Btr197  0.313
2011 Sneddon MW, Faeder JR, Emonet T. Efficient modeling, simulation and coarse-graining of biological complexity with NFsim. Nature Methods. 8: 177-83. PMID 21186362 DOI: 10.1038/Nmeth.1546  0.412
2010 Gong H, Zuliani P, Komuravelli A, Faeder JR, Clarke EM. Analysis and verification of the HMGB1 signaling pathway. Bmc Bioinformatics. 11: S10. PMID 21106117 DOI: 10.1186/1471-2105-11-S7-S10  0.359
2010 Nag A, Faeder JR, Goldstein B. Shaping the response: the role of FcεRI and Syk expression levels in mast cell signaling. Iet Systems Biology. 4: 334-47. PMID 21073233 DOI: 10.1049/Iet-Syb.2010.0006  0.316
2010 Monine MI, Posner RG, Savage PB, Faeder JR, Hlavacek WS. Modeling multivalent ligand-receptor interactions with steric constraints on configurations of cell-surface receptor aggregates. Biophysical Journal. 98: 48-56. PMID 20085718 DOI: 10.1016/J.Bpj.2009.09.043  0.325
2009 Indest KJ, Buchholz WG, Faeder JR, Setlow P. Workshop report: modeling the molecular mechanism of bacterial spore germination and elucidating reasons for germination heterogeneity. Journal of Food Science. 74: R73-8. PMID 19723224 DOI: 10.1111/J.1750-3841.2009.01245.X  0.325
2009 Hlavacek WS, Faeder JR. The complexity of cell signaling and the need for a new mechanics. Science Signaling. 2: pe46. PMID 19638613 DOI: 10.1126/Scisignal.281Pe46  0.347
2009 Faeder JR, Blinov ML, Hlavacek WS. Rule-based modeling of biochemical systems with BioNetGen. Methods in Molecular Biology (Clifton, N.J.). 500: 113-67. PMID 19399430 DOI: 10.1007/978-1-59745-525-1_5  0.405
2009 Barua D, Faeder JR, Haugh JM. A bipolar clamp mechanism for activation of Jak-family protein tyrosine kinases. Plos Computational Biology. 5: e1000364. PMID 19381268 DOI: 10.1371/Journal.Pcbi.1000364  0.32
2009 Nag A, Monine MI, Faeder JR, Goldstein B. Aggregation of membrane proteins by cytosolic cross-linkers: theory and simulation of the LAT-Grb2-SOS1 system. Biophysical Journal. 96: 2604-23. PMID 19348745 DOI: 10.1016/J.Bpj.2009.01.019  0.367
2009 Hu B, Matthew Fricke G, Faeder JR, Posner RG, Hlavacek WS. GetBonNie for building, analyzing and sharing rule-based models. Bioinformatics (Oxford, England). 25: 1457-60. PMID 19321734 DOI: 10.1093/Bioinformatics/Btp173  0.34
2009 Colvin J, Monine MI, Faeder JR, Hlavacek WS, Von Hoff DD, Posner RG. Simulation of large-scale rule-based models. Bioinformatics (Oxford, England). 25: 910-7. PMID 19213740 DOI: 10.1093/Bioinformatics/Btp066  0.389
2009 An GC, Faeder JR. Detailed qualitative dynamic knowledge representation using a BioNetGen model of TLR-4 signaling and preconditioning. Mathematical Biosciences. 217: 53-63. PMID 18835283 DOI: 10.1016/J.Mbs.2008.08.013  0.366
2008 Goldstein B, Coombs D, Faeder JR, Hlavacek WS. Kinetic proofreading model. Advances in Experimental Medicine and Biology. 640: 82-94. PMID 19065786 DOI: 10.1007/978-0-387-09789-3_8  0.322
2008 Borisov NM, Chistopolsky AS, Faeder JR, Kholodenko BN. Domain-oriented reduction of rule-based network models Iet Systems Biology. 2: 342-351. PMID 19045829 DOI: 10.1049/Iet-Syb:20070081  0.367
2008 Yang J, Monine MI, Faeder JR, Hlavacek WS. Kinetic Monte Carlo method for rule-based modeling of biochemical networks. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 78: 031910. PMID 18851068 DOI: 10.1103/Physreve.78.031910  0.351
2008 Lipniacki T, Hat B, Faeder JR, Hlavacek WS. Stochastic effects and bistability in T cell receptor signaling. Journal of Theoretical Biology. 254: 110-22. PMID 18556025 DOI: 10.1016/J.Jtbi.2008.05.001  0.385
2008 Barua D, Faeder JR, Haugh JM. Computational models of tandem SRC homology 2 domain interactions and application to phosphoinositide 3-kinase. The Journal of Biological Chemistry. 283: 7338-45. PMID 18204097 DOI: 10.1074/Jbc.M708359200  0.304
2007 Torigoe C, Faeder JR, Oliver JM, Goldstein B. Kinetic proofreading of ligand-FcepsilonRI interactions may persist beyond LAT phosphorylation. Journal of Immunology (Baltimore, Md. : 1950). 178: 3530-5. PMID 17339448 DOI: 10.4049/Jimmunol.178.6.3530  0.337
2007 Barua D, Faeder JR, Haugh JM. Structure-based kinetic models of modular signaling protein function: focus on Shp2. Biophysical Journal. 92: 2290-300. PMID 17208977 DOI: 10.1529/Biophysj.106.093484  0.387
2007 Faeder J, Monine M, Nag A, Goldstein B, Hlavacek W. Rule-based modeling of signal transduction Journal of Critical Care. 22: 349-350. DOI: 10.1016/J.Jcrc.2007.10.033  0.346
2006 Hlavacek WS, Faeder JR, Blinov ML, Posner RG, Hucka M, Fontana W. Rules for modeling signal-transduction systems. Science's Stke : Signal Transduction Knowledge Environment. 2006: re6. PMID 16849649 DOI: 10.1126/Stke.3442006Re6  0.377
2006 Blinov ML, Faeder JR, Goldstein B, Hlavacek WS. A network model of early events in epidermal growth factor receptor signaling that accounts for combinatorial complexity. Bio Systems. 83: 136-51. PMID 16233948 DOI: 10.1016/J.Biosystems.2005.06.014  0.389
2005 Faeder J, Ladanyi BM. Solvation dynamics in reverse micelles: the role of headgroup-solute interactions. The Journal of Physical Chemistry. B. 109: 6732-40. PMID 16851757 DOI: 10.1021/Jp045202M  0.586
2005 Blinov ML, Faeder JR, Yang J, Goldstein B, Hlavacek WS. 'On-the-fly' or 'generate-first' modeling? Nature Biotechnology. 23: 1344-5; author reply. PMID 16273053 DOI: 10.1038/Nbt1105-1344  0.312
2004 Blinov ML, Faeder JR, Goldstein B, Hlavacek WS. BioNetGen: software for rule-based modeling of signal transduction based on the interactions of molecular domains. Bioinformatics (Oxford, England). 20: 3289-91. PMID 15217809 DOI: 10.1093/Bioinformatics/Bth378  0.404
2004 Goldstein B, Faeder JR, Hlavacek WS. Mathematical and computational models of immune-receptor signalling. Nature Reviews. Immunology. 4: 445-56. PMID 15173833 DOI: 10.1038/Nri1374  0.387
2003 Hlavacek WS, Faeder JR, Blinov ML, Perelson AS, Goldstein B. The complexity of complexes in signal transduction. Biotechnology and Bioengineering. 84: 783-94. PMID 14708119 DOI: 10.1002/Bit.10842  0.353
2003 Faeder JR, Hlavacek WS, Reischl I, Blinov ML, Metzger H, Redondo A, Wofsy C, Goldstein B. Investigation of early events in Fc epsilon RI-mediated signaling using a detailed mathematical model. Journal of Immunology (Baltimore, Md. : 1950). 170: 3769-81. PMID 12646643 DOI: 10.4049/Jimmunol.170.7.3769  0.357
2003 Faeder J, Albert MV, Ladanyi BM. Molecular dynamics simulations of the interior of aqueous reverse micelles: A comparison between sodium and potassium counterions Langmuir. 19: 2514-2520. DOI: 10.1021/La026755W  0.568
2002 Goldstein B, Faeder JR, Hlavacek WS, Blinov ML, Redondo A, Wofsy C. Modeling the early signaling events mediated by FcepsilonRI. Molecular Immunology. 38: 1213-9. PMID 12217386 DOI: 10.1016/S0161-5890(02)00066-4  0.359
2001 Faeder J, Ladanyi BM. Solvation dynamics in aqueous reverse micelles: A computer simulation study Journal of Physical Chemistry B. 105: 11148-11158. DOI: 10.1021/Jp010632N  0.588
2000 Faeder J, Ladanyi BM. Molecular Dynamics Simulations of the Interior of Aqueous Reverse Micelles The Journal of Physical Chemistry B. 104: 1033-1046. DOI: 10.1021/Jp993076U  0.593
2000 Parson R, Faeder J, Delaney N. Charge flow and solvent dynamics in the photodissociation of solvated molecular ions Journal of Physical Chemistry A. 104: 9663-9665. DOI: 10.1021/Jp0019916  0.317
1998 Maslen PE, Faeder J, Parson R. An effective Hamiltonian for an electronically excited solute in a polarizable molecular solvent Molecular Physics. 94: 693-706. DOI: 10.1080/002689798167854  0.314
1998 Faeder J, Parson R. Ultrafast reaction dynamics in cluster ions: Simulation of the transient photoelectron spectrum of I- 2 Arn photodissociation Journal of Chemical Physics. 108: 3909-3914. DOI: 10.1063/1.475793  0.334
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