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Hank F. Kung - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Pharmacology, Organic Chemistry, Pharmaceutical Chemistry
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251 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Zha Z, Ploessl K, Choi SR, Alexoff D, Kung HF. Preclinical evaluation of [F]D3FSP, deuterated AV-45, for imaging of β-amyloid in the brain. Nuclear Medicine and Biology. PMID 32245565 DOI: 10.1016/J.Nucmedbio.2020.03.003  0.41
2020 Xu X, Zhu H, Liu F, Zhang Y, Yang J, Zhang L, Xie Q, Zhu L, Li N, Kung HF, Yang Z. Dynamic PET/CT imaging of F-(2S, 4R)4-fluoroglutamine in healthy volunteers and oncological patients. European Journal of Nuclear Medicine and Molecular Imaging. PMID 32166510 DOI: 10.1007/S00259-019-04543-W  0.357
2020 Liu S, Wu R, Sun Y, Ploessl K, Zhang Y, Liu Y, Wu Z, Zhu L, Kung HF. Design, synthesis and evaluation of a novel glutamine derivative (2S,4R)-2-amino-4-cyano-4-[18F]fluorobutanoic acid New Journal of Chemistry. 44: 9109-9117. DOI: 10.1039/D0Nj00410C  0.32
2019 Zhang L, Zhang A, Yao X, Zhang Y, Liu F, Hong H, Zha Z, Liu Y, Wu Z, Qiao J, Zhu L, Kung HF. An improved preparation of [ F]AV-45 by simplified solid-phase extraction purification. Journal of Labelled Compounds & Radiopharmaceuticals. PMID 31697847 DOI: 10.1002/Jlcr.3813  0.353
2019 Zhao R, Zha Z, Yao X, Ploessl K, Choi SR, Liu F, Zhu L, Kung HF. VMAT2 imaging agent, D6-[F]FP-(+)-DTBZ: Improved radiosynthesis, purification by solid-phase extraction and characterization. Nuclear Medicine and Biology. 72: 26-35. PMID 31330409 DOI: 10.1016/J.Nucmedbio.2019.07.002  0.372
2019 Yao X, Zha Z, Zhao R, Choi SR, Ploessl K, Liu F, Zhu L, Kung HF. Optimization of solid-phase extraction (SPE) in the preparation of [F]D3FSP: A new PET imaging agent for mapping Aβ plaques. Nuclear Medicine and Biology. 71: 54-64. PMID 31152974 DOI: 10.1016/J.Nucmedbio.2019.05.002  0.419
2019 Sun M, Xiao H, Hong H, Zhang A, Zhang Y, Liu Y, Zhu L, Kung HF, Qiao J. Rapid screening of nine unradiolabeled candidate compounds as PET brain imaging agents using cassette-wave microdosing and LC-MS/MS. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1121: 28-38. PMID 31100605 DOI: 10.1016/J.Jchromb.2019.05.006  0.335
2019 Huang Y, Liu S, Wu R, Zhang L, Zhang Y, Hong H, Zhang A, Xiao H, Liu Y, Wu Z, Zhu L, Kung HF. Synthesis and preliminary evaluation of a novel glutamine derivative: (2S,4S)4-[F]FEBGln. Bioorganic & Medicinal Chemistry Letters. PMID 30871772 DOI: 10.1016/J.Bmcl.2019.03.012  0.367
2019 Zhang Y, Zhang L, Yang J, Wu Z, Ploessl K, Zha Z, Liu F, Xu X, Zhu H, Yang Z, Zhu L, Kung HF. Initial experience in synthesis of (2S,4R)-4-[18F]fluoroglutamine for clinical application. Journal of Labelled Compounds & Radiopharmaceuticals. PMID 30861162 DOI: 10.1002/Jlcr.3719  0.358
2019 Zhu H, Liu F, Zhang Y, Yang J, Xu X, Guo X, Liu T, Li N, Zhu L, Kung HF, Yang Z. (2S,4R)-4-[F]Fluoroglutamine as a PET Indicator for Bone Marrow Metabolism Dysfunctional: from Animal Experiments to Clinical Application. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 30793240 DOI: 10.1007/S11307-019-01319-4  0.31
2019 Zhang L, Yao X, Cao J, Hong H, Zhang A, Zhao R, Zhang Y, Zha Z, Liu Y, Qiao J, Zhu L, Kung HF. In vivo ester hydrolysis as a new approach in development of PET tracers for imaging hypoxia. Molecular Pharmaceutics. PMID 30676751 DOI: 10.1021/Acs.Molpharmaceut.8B01131  0.372
2018 Xu X, Zhu H, Liu F, Zhang Y, Yang J, Zhang L, Zhu L, Li N, Kung HF, Yang Z. Imaging Brain Metastasis Patients With 18F-(2S,4R)-4-Fluoroglutamine. Clinical Nuclear Medicine. PMID 30179907 DOI: 10.1097/Rlu.0000000000002257  0.395
2018 Zhang Y, Liu F, Xiao H, Yao X, Li G, Choi SR, Ploessl K, Zha Z, Zhu L, Kung HF. [F]Diphenyl sulfide derivatives for imaging serotonin transporter (SERT) in the brain. Nuclear Medicine and Biology. 66: 1-9. PMID 30096380 DOI: 10.1016/J.Nucmedbio.2018.06.008  0.396
2018 Liu F, Xu X, Zhu H, Zhang Y, Yang J, Zhang L, Li N, Zhu L, Kung HF, Yang Z. PET Imaging of 18F-(2S,4R)4-fluoroglutamine Accumulation in Breast Cancer: from Xenografts to Patients. Molecular Pharmaceutics. PMID 29985631 DOI: 10.1021/Acs.Molpharmaceut.8B00430  0.378
2018 Liu F, Zhu L, Choi SR, Plössl K, Zha Z, Kung HF. Deuterium substituted 2-(2'-((Dimethylamino)methyl)-4'- [ F](fluoropropoxy)phenyl-thio)benzenamine as a serotonin transporter imaging agent. Journal of Labelled Compounds & Radiopharmaceuticals. PMID 29644713 DOI: 10.1002/Jlcr.3626  0.462
2018 Xiao H, Sun M, Zhao R, Hong H, Zhang A, Zhang S, Liu F, Zhang Y, Liu Y, Zhu L, Kung HF, Qiao J. Developing a cassette microdosing approach to enhance the throughput of PET imaging agent screening. Journal of Pharmaceutical and Biomedical Analysis. 154: 48-56. PMID 29533858 DOI: 10.1016/J.Jpba.2018.02.063  0.323
2018 Zha Z, Ploessl K, Lieberman BP, Wang L, Kung HF. Alanine and glycine conjugates of [F](2S,4R)4-fluoroglutamine for tumor imaging. Nuclear Medicine and Biology. 60: 19-28. PMID 29525446 DOI: 10.1016/J.Nucmedbio.2018.02.001  0.355
2018 Dunphy MPS, Harding JJ, Venneti S, Zhang H, Burnazi EM, Bromberg J, Omuro AM, Hsieh JJ, Mellinghoff IK, Staton K, Pressl C, Beattie BJ, Zanzonico PB, Gerecitano JF, Kelsen DP, ... Kung HF, et al. In Vivo PET Assay of Tumor Glutamine Flux and Metabolism: In-Human Trial of 18F-(2S,4R )-4-Fluoroglutamine. Radiology. 162610. PMID 29388903 DOI: 10.1148/Radiol.2017162610  0.344
2017 Zha Z, Ploessl K, Choi SR, Wu Z, Zhu L, Kung HF. Synthesis and evaluation of a novel urea-basedGa-complex for imaging PSMA binding in tumor. Nuclear Medicine and Biology. 59: 36-47. PMID 29459281 DOI: 10.1016/J.Nucmedbio.2017.12.007  0.352
2017 Liu F, Choi SR, Zha Z, Ploessl K, Zhu L, Kung HF. Deuterated 18F-9-O-hexadeutero-3-fluoropropoxyl-(+)-dihydrotetrabenazine (D6-FP-(+)-DTBZ): A vesicular monoamine transporter 2 (VMAT2) imaging agent. Nuclear Medicine and Biology. 57: 42-49. PMID 29306111 DOI: 10.1016/J.Nucmedbio.2017.11.009  0.428
2017 Kung HF, Ploessl K, Mankoff D, Zhu L, Zhou R. Metabolic Imaging of Glutamine in Cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 28232608 DOI: 10.2967/Jnumed.116.182345  0.368
2017 Zhou R, Pantel AR, Li S, Lieberman BP, Ploessl K, Choi H, Blankemeyer E, Lee H, Kung H, Mach RH, Mankoff D. [18F](2S,4R)4-Fluoroglutamine PET Detects Glutamine Pool Size Changes in Triple Negative Breast Cancer in Response to Glutaminase Inhibition. Cancer Research. PMID 28202527 DOI: 10.1158/0008-5472.Can-16-1945  0.339
2017 Cao J, Liu Y, Zhang L, Du F, Ci Y, Zhang Y, Xiao H, Yao X, Shi S, Zhu L, Kung HF, Qiao J. Synthesis of novel PEG-modified nitroimidazole derivatives via “hot-click” reaction and their biological evaluation as potential PET imaging agent for tumors Journal of Radioanalytical and Nuclear Chemistry. 312: 263-276. DOI: 10.1007/S10967-017-5210-5  0.368
2016 Jeitner TM, Kristoferson E, Azcona JA, Pinto JT, Stalnecker C, Erickson JW, Kung HF, Li J, Ploessl K, Cooper AJL. Fluorination at the 4 position alters the substrate behavior of L-glutamine and L-glutamate: Implications for positron emission tomography of neoplasias. Journal of Fluorine Chemistry. 192: 58-67. PMID 28546645 DOI: 10.1016/J.Jfluchem.2016.10.008  0.302
2016 Song J, Wu Z, Wangtrakuldee P, Choi SR, Zha Z, Ploessl K, Mach RH, Kung HF. 4-(((4-Iodophenyl)methyl)-4H-1,2,4-triazol-4-ylamino)-benzonitrile: A potential imaging agent for aromatase. Journal of Medicinal Chemistry. PMID 27690428 DOI: 10.1021/Acs.Jmedchem.6B00849  0.402
2016 Wu Z, Zha Z, Choi SR, Plössl K, Zhu L, Kung HF. New (68)Ga-PhenA bisphosphonates as potential bone imaging agents. Nuclear Medicine and Biology. 43: 360-71. PMID 27260777 DOI: 10.1016/J.Nucmedbio.2016.03.002  0.312
2016 Qiao H, Zhang Y, Wu Z, Zhu L, Choi SR, Ploessl K, Kung HF. One-step preparation of [(18)F]FPBM for PET imaging of serotonin transporter (SERT) in the brain. Nuclear Medicine and Biology. 43: 470-477. PMID 27236282 DOI: 10.1016/J.Nucmedbio.2016.04.003  0.463
2016 Zha Z, Song J, Choi SR, Wu Z, Ploessl K, Smith M, Kung HF. (68)Ga-Bivalent Polypegylated Styrylpyridine Conjugates for Imaging Aβ Plaques in Cerebral Amyloid Angiopathy (CAA). Bioconjugate Chemistry. PMID 27045547 DOI: 10.1021/Acs.Bioconjchem.6B00127  0.375
2015 Wu X, Zhou X, Zhang S, Zhang Y, Deng A, Han J, Zhu L, Kung HF, Qiao J. Brain uptake of a non-radioactive pseudo-carrier and its effect on the biodistribution of [(18)F]AV-133 in mouse brain. Nuclear Medicine and Biology. 42: 630-6. PMID 25910857 DOI: 10.1016/J.Nucmedbio.2015.03.009  0.397
2015 Venneti S, Dunphy MP, Zhang H, Pitter KL, Zanzonico P, Campos C, Carlin SD, La Rocca G, Lyashchenko S, Ploessl K, Rohle D, Omuro AM, Cross JR, Brennan CW, Weber WA, ... ... Kung HF, et al. Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo. Science Translational Medicine. 7: 274ra17. PMID 25673762 DOI: 10.1126/Scitranslmed.Aaa1009  0.403
2014 Wu Z, Zha Z, Li G, Lieberman BP, Choi SR, Ploessl K, Kung HF. [(18)F](2S,4S)-4-(3-Fluoropropyl)glutamine as a tumor imaging agent. Molecular Pharmaceutics. 11: 3852-66. PMID 25095908 DOI: 10.1021/Mp500236Y  0.366
2014 Zhu L, Ploessl K, Kung HF. PET/SPECT imaging agents for neurodegenerative diseases. Chemical Society Reviews. 43: 6683-91. PMID 24676152 DOI: 10.1039/C3Cs60430F  0.395
2014 Graham TJ, Lambert RF, Ploessl K, Kung HF, Doyle AG. Enantioselective radiosynthesis of positron emission tomography (PET) tracers containing [¹⁸F]fluorohydrins. Journal of the American Chemical Society. 136: 5291-4. PMID 24628021 DOI: 10.1021/Ja5025645  0.334
2014 Wang L, Lieberman BP, Ploessl K, Kung HF. Synthesis and evaluation of ¹⁸F labeled FET prodrugs for tumor imaging. Nuclear Medicine and Biology. 41: 58-67. PMID 24183614 DOI: 10.1016/J.Nucmedbio.2013.09.011  0.362
2014 Liu Y, Yue F, Tang R, Tao G, Pan X, Zhu L, Kung HF, Chan P. Progressive loss of striatal dopamine terminals in MPTP-induced acute parkinsonism in cynomolgus monkeys using vesicular monoamine transporter type 2 PET imaging ([(18)F]AV-133). Neuroscience Bulletin. 30: 409-16. PMID 24061965 DOI: 10.1007/S12264-013-1374-3  0.382
2014 Venneti S, Dunphy M, Zhang H, Pitter K, Campos C, Carlin S, Lyashchenko S, Ploessl C, Rohle D, Omuro A, Cross J, Brennan C, Weber W, Holland E, Mellinghoff I, ... Kung H, et al. TM-15 * GLUTAMINE BASED PET IMAGING FACILITATES ENHANCED METABOLIC DETECTION OF GLIOMAS IN VIVO Neuro-Oncology. 16: v216-v216. DOI: 10.1093/Neuonc/Nou278.14  0.391
2013 Zhu L, Ploessl K, Kung HF. Chemistry. Expanding the scope of fluorine tags for PET imaging. Science (New York, N.Y.). 342: 429-30. PMID 24159034 DOI: 10.1126/Science.1245011  0.394
2013 Zhu L, Li G, Choi SR, Plössl K, Chan P, Qiao H, Zha Z, Kung HF. An improved preparation of [18F]FPBM: a potential serotonin transporter (SERT) imaging agent. Nuclear Medicine and Biology. 40: 974-9. PMID 24035549 DOI: 10.1016/J.Nucmedbio.2013.08.002  0.452
2013 Lemoine L, Lieberman BP, Ploessl K, Zheng P, Kung HF. Characterization of FlipIDAM as a SERT-selective SPECT imaging agent. Nuclear Medicine and Biology. 40: 879-86. PMID 23856117 DOI: 10.1016/J.Nucmedbio.2013.06.001  0.403
2013 Zheng P, Lieberman BP, Ploessl K, Lemoine L, Miller S, Kung HF. A new single-photon emission computed tomography (SPECT) imaging agent for serotonin transporters: [(125)I]Flip-IDAM, (2-((2-((dimethylamino)methyl)-4-iodophenyl)thio)phenyl)methanol. Bioorganic & Medicinal Chemistry Letters. 23: 869-72. PMID 23265880 DOI: 10.1016/J.Bmcl.2012.11.043  0.439
2012 Kung HF. The β-Amyloid Hypothesis in Alzheimer's Disease: Seeing Is Believing. Acs Medicinal Chemistry Letters. 3: 265-7. PMID 24936237 DOI: 10.1021/Ml300058M  0.368
2012 Ploessl K, Wang L, Lieberman BP, Qu W, Kung HF. Comparative evaluation of 18F-labeled glutamic acid and glutamine as tumor metabolic imaging agents. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 1616-24. PMID 22935578 DOI: 10.2967/Jnumed.111.101279  0.367
2012 Zhu L, Qiao H, Lieberman BP, Wu J, Liu Y, Pan Z, Ploessl K, Choi SR, Chan P, Kung HF. Imaging of VMAT2 binding sites in the brain by (18)F-AV-133: the effect of a pseudo-carrier. Nuclear Medicine and Biology. 39: 897-904. PMID 22749185 DOI: 10.1016/J.Nucmedbio.2012.05.002  0.404
2012 Qiao H, Zhu L, Lieberman BP, Zha Z, Plössl K, Kung HF. Synthesis and evaluation of novel tropane derivatives as potential PET imaging agents for the dopamine transporter. Bioorganic & Medicinal Chemistry Letters. 22: 4303-6. PMID 22658558 DOI: 10.1016/J.Bmcl.2012.05.030  0.45
2012 Wang L, Zha Z, Qu W, Qiao H, Lieberman BP, Plössl K, Kung HF. Synthesis and evaluation of 18F labeled alanine derivatives as potential tumor imaging agents. Nuclear Medicine and Biology. 39: 933-43. PMID 22542392 DOI: 10.1016/J.Nucmedbio.2012.03.007  0.391
2012 Choi SR, Schneider JA, Bennett DA, Beach TG, Bedell BJ, Zehntner SP, Krautkramer MJ, Kung HF, Skovronsky DM, Hefti F, Clark CM. Correlation of amyloid PET ligand florbetapir F 18 binding with Aβ aggregation and neuritic plaque deposition in postmortem brain tissue. Alzheimer Disease and Associated Disorders. 26: 8-16. PMID 22354138 DOI: 10.1097/Wad.0B013E31821300Bc  0.429
2012 Villemagne VL, Okamura N, Pejoska S, Drago J, Mulligan RS, Chételat G, O'Keefe G, Jones G, Kung HF, Pontecorvo M, Masters CL, Skovronsky DM, Rowe CC. Differential diagnosis in Alzheimer's disease and dementia with Lewy bodies via VMAT2 and amyloid imaging. Neuro-Degenerative Diseases. 10: 161-5. PMID 22261520 DOI: 10.1159/000334535  0.392
2011 Virostko J, Henske J, Vinet L, Lamprianou S, Dai C, Radhika A, Baldwin RM, Ansari MS, Hefti F, Skovronsky D, Kung HF, Herrera PL, Peterson TE, Meda P, Powers AC. Multimodal image coregistration and inducible selective cell ablation to evaluate imaging ligands. Proceedings of the National Academy of Sciences of the United States of America. 108: 20719-24. PMID 22143775 DOI: 10.1073/Pnas.1109480108  0.413
2011 Lieberman BP, Ploessl K, Wang L, Qu W, Zha Z, Wise DR, Chodosh LA, Belka G, Thompson CB, Kung HF. PET imaging of glutaminolysis in tumors by 18F-(2S,4R)4-fluoroglutamine. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 52: 1947-55. PMID 22095958 DOI: 10.2967/Jnumed.111.093815  0.345
2011 Carberry P, Carpenter AP, Kung HF. Fluoride-18 radiolabeling of peptides bearing an aminooxy functional group to a prosthetic ligand via an oxime bond. Bioorganic & Medicinal Chemistry Letters. 21: 6992-5. PMID 22024031 DOI: 10.1016/J.Bmcl.2011.09.124  0.328
2011 Zha Z, Choi SR, Ploessl K, Lieberman BP, Qu W, Hefti F, Mintun M, Skovronsky D, Kung HF. Multidentate (18)F-polypegylated styrylpyridines as imaging agents for Aβ plaques in cerebral amyloid angiopathy (CAA). Journal of Medicinal Chemistry. 54: 8085-98. PMID 22011144 DOI: 10.1021/Jm2009106  0.418
2011 Villemagne VL, Okamura N, Pejoska S, Drago J, Mulligan RS, Chételat G, Ackermann U, O'Keefe G, Jones G, Gong S, Tochon-Danguy H, Kung HF, Masters CL, Skovronsky DM, Rowe CC. In vivo assessment of vesicular monoamine transporter type 2 in dementia with lewy bodies and Alzheimer disease. Archives of Neurology. 68: 905-12. PMID 21747030 DOI: 10.1001/Archneurol.2011.142  0.357
2011 Lister-James J, Pontecorvo MJ, Clark C, Joshi AD, Mintun MA, Zhang W, Lim N, Zhuang Z, Golding G, Choi SR, Benedum TE, Kennedy P, Hefti F, Carpenter AP, Kung HF, et al. Florbetapir f-18: a histopathologically validated Beta-amyloid positron emission tomography imaging agent. Seminars in Nuclear Medicine. 41: 300-4. PMID 21624563 DOI: 10.1053/J.Semnuclmed.2011.03.001  0.455
2011 Zheng P, Lieberman BP, Choi SR, Plöessl K, Kung HF. Synthesis and biological evaluation of 3-alkyl-dihydrotetrabenazine derivatives as vesicular monoamine transporter-2 (VMAT2) ligands. Bioorganic & Medicinal Chemistry Letters. 21: 3435-8. PMID 21531556 DOI: 10.1016/J.Bmcl.2011.03.113  0.411
2011 Zha Z, Zhu L, Liu Y, Du F, Gan H, Qiao J, Kung HF. Synthesis and evaluation of two novel 2-nitroimidazole derivatives as potential PET radioligands for tumor imaging. Nuclear Medicine and Biology. 38: 501-8. PMID 21531287 DOI: 10.1016/J.Nucmedbio.2010.11.001  0.364
2011 Wang L, Lieberman BP, Plössl K, Qu W, Kung HF. Synthesis and comparative biological evaluation of L- and D-isomers of 18F-labeled fluoroalkyl phenylalanine derivatives as tumor imaging agents. Nuclear Medicine and Biology. 38: 301-12. PMID 21492778 DOI: 10.1016/J.Nucmedbio.2010.10.004  0.37
2011 Liu J, Zhu L, Plössl K, Lieberman BP, Kung HF. Synthesis and evaluation of novel N-fluoropyridyl derivatives of tropane as potential PET imaging agents for the dopamine transporter. Bioorganic & Medicinal Chemistry Letters. 21: 2962-5. PMID 21458259 DOI: 10.1016/J.Bmcl.2011.03.051  0.444
2011 Carberry P, Lieberman BP, Ploessl K, Choi SR, Haase DN, Kung HF. New F-18 prosthetic group via oxime coupling. Bioconjugate Chemistry. 22: 642-53. PMID 21452846 DOI: 10.1021/Bc1004262  0.393
2011 Clark CM, Schneider JA, Bedell BJ, Beach TG, Bilker WB, Mintun MA, Pontecorvo MJ, Hefti F, Carpenter AP, Flitter ML, Krautkramer MJ, Kung HF, Coleman RE, Doraiswamy PM, Fleisher AS, et al. Use of florbetapir-PET for imaging beta-amyloid pathology. Jama. 305: 275-83. PMID 21245183 DOI: 10.1001/Jama.2010.2008  0.398
2011 Wang L, Qu W, Lieberman BP, Plössl K, Kung HF. Synthesis, uptake mechanism characterization and biological evaluation of (18)F labeled fluoroalkyl phenylalanine analogs as potential PET imaging agents. Nuclear Medicine and Biology. 38: 53-62. PMID 21220129 DOI: 10.1016/J.Nucmedbio.2010.07.005  0.376
2011 Qu W, Zha Z, Ploessl K, Lieberman BP, Zhu L, Wise DR, Thompson CB, Kung HF. Synthesis of optically pure 4-fluoro-glutamines as potential metabolic imaging agents for tumors. Journal of the American Chemical Society. 133: 1122-33. PMID 21190335 DOI: 10.1021/Ja109203D  0.319
2010 Hefti FF, Kung HF, Kilbourn MR, Carpenter AP, Clark CM, Skovronsky DM. (18)F-AV-133: A Selective VMAT2-binding Radiopharmaceutical for PET Imaging of Dopaminergic Neurons. Pet Clinics. 5: 75-82. PMID 27157484 DOI: 10.1016/J.Cpet.2010.02.001  0.334
2010 Liu Y, Zhu L, Plössl K, Choi SR, Qiao H, Sun X, Li S, Zha Z, Kung HF. Optimization of automated radiosynthesis of [18F]AV-45: a new PET imaging agent for Alzheimer's disease. Nuclear Medicine and Biology. 37: 917-25. PMID 21055622 DOI: 10.1016/J.Nucmedbio.2010.05.001  0.402
2010 Wang JL, Deutsch EC, Oya S, Kung HF. FlipADAM: a potential new SPECT imaging agent for the serotonin transporter. Nuclear Medicine and Biology. 37: 577-86. PMID 20610162 DOI: 10.1016/J.Nucmedbio.2010.02.010  0.553
2010 Tu Z, Xu J, Jones LA, Li S, Zeng D, Kung MP, Kung HF, Mach RH. Radiosynthesis and biological evaluation of a promising sigma(2)-receptor ligand radiolabeled with fluorine-18 or iodine-125 as a PET/SPECT probe for imaging breast cancer. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 68: 2268-73. PMID 20594864 DOI: 10.1016/J.Apradiso.2010.06.004  0.38
2010 Wang L, Qu W, Lieberman B, Ploessl K, Kung HF. Synthesis and in vitro evaluation of 18F labeled tyrosine derivatives as potential positron emission tomography (PET) imaging agents. Bioorganic & Medicinal Chemistry Letters. 20: 3482-5. PMID 20529679 DOI: 10.1016/J.Bmcl.2010.05.007  0.357
2010 Zhu X, Li DP, Fan WG, Lin MC, Wang JL, Lin SQ, Huang JQ, Kung HF. Lack of association between the GRP78 polymorphisms in the promoter and 3' UTR and susceptibility to chronic HBV infection in a Chinese Han population. Bmc Medical Genetics. 11: 83. PMID 20525207 DOI: 10.1186/1471-2350-11-83  0.327
2010 Wong DF, Rosenberg PB, Zhou Y, Kumar A, Raymont V, Ravert HT, Dannals RF, Nandi A, Brasić JR, Ye W, Hilton J, Lyketsos C, Kung HF, Joshi AD, Skovronsky DM, et al. In vivo imaging of amyloid deposition in Alzheimer disease using the radioligand 18F-AV-45 (florbetapir [corrected] F 18). Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 913-20. PMID 20501908 DOI: 10.2967/Jnumed.109.069088  0.39
2010 Wang JL, Oya S, Parhi AK, Lieberman BP, Ploessl K, Hou C, Kung HF. In vivo studies of the SERT-selective [18F]FPBM and VMAT2-selective [18F]AV-133 radiotracers in a rat model of Parkinson's disease. Nuclear Medicine and Biology. 37: 479-86. PMID 20447560 DOI: 10.1016/J.Nucmedbio.2010.01.006  0.529
2010 Song PJ, Barc C, Arlicot N, Guilloteau D, Bernard S, Sarradin P, Chalon S, Garreau L, Kung HF, Lantier F, Vergote J. Evaluation of prion deposits and microglial activation in scrapie-infected mice using molecular imaging probes. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 12: 576-82. PMID 20376566 DOI: 10.1007/S11307-010-0321-1  0.308
2010 Zhu L, Liu Y, Plössl K, Lieberman B, Liu J, Kung HF. An improved radiosynthesis of [18F]AV-133: a PET imaging agent for vesicular monoamine transporter 2. Nuclear Medicine and Biology. 37: 133-41. PMID 20152712 DOI: 10.1016/J.Nucmedbio.2009.10.005  0.393
2010 Okamura N, Villemagne VL, Drago J, Pejoska S, Dhamija RK, Mulligan RS, Ellis JR, Ackermann U, O'Keefe G, Jones G, Kung HF, Pontecorvo MJ, Skovronsky D, Rowe CC. In vivo measurement of vesicular monoamine transporter type 2 density in Parkinson disease with (18)F-AV-133. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 223-8. PMID 20080893 DOI: 10.2967/Jnumed.109.070094  0.361
2010 Pejoska S, Rowe CC, Drago J, Okamura N, Mulligan R, Kung HF, Pontecorvo M, Masters CL, Skovronsky D, Villemagne VL. 18F-AV-133 VMAT2 imaging in the differential diagnosis of dementia with Lewy Bodies from Alzheimer's disease Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.08.006  0.342
2010 Zhuang Z, Kung M, Ono M, Hou C, Kung HF. Syntheses of Two Potential Ligands for Tc-99m Labeling as Diagnosis Agents of Alzheimer's Disease Chinese Journal of Chemistry. 21: 824-832. DOI: 10.1002/Cjoc.20030210722  0.317
2009 Serdons K, Van Laere K, Janssen P, Kung HF, Bormans G, Verbruggen A. Synthesis and evaluation of three 18F-labeled aminophenylbenzothiazoles as amyloid imaging agents. Journal of Medicinal Chemistry. 52: 7090-102. PMID 19877643 DOI: 10.1021/Jm900871V  0.438
2009 Choi SR, Golding G, Zhuang Z, Zhang W, Lim N, Hefti F, Benedum TE, Kilbourn MR, Skovronsky D, Kung HF. Preclinical properties of 18F-AV-45: a PET agent for Abeta plaques in the brain. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 50: 1887-94. PMID 19837759 DOI: 10.2967/Jnumed.109.065284  0.415
2009 Wang JL, Parhi AK, Oya S, Lieberman B, Kung HF. In vivo characterization of a series of 18F-diaryl sulfides (18F-2-(2'-((dimethylamino)methyl)-4'-(fluoroalkoxy)phenylthio)benzenamine) for PET imaging of the serotonin transporter. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 50: 1509-17. PMID 19690040 DOI: 10.2967/Jnumed.108.060723  0.556
2009 Zhu L, Liu J, Kung HF. Synthesis and evaluation of 2-amino-dihydrotetrabenzine derivatives as probes for imaging vesicular monoamine transporter-2. Bioorganic & Medicinal Chemistry Letters. 19: 5026-8. PMID 19632829 DOI: 10.1016/J.Bmcl.2009.07.048  0.357
2009 Wey SP, Weng CC, Lin KJ, Yao CH, Yen TC, Kung HF, Skovronsky D, Kung MP. Validation of an (18)F-labeled biphenylalkyne as a positron emission tomography imaging agent for beta-amyloid plaques. Nuclear Medicine and Biology. 36: 411-7. PMID 19423009 DOI: 10.1016/J.Nucmedbio.2009.01.013  0.439
2009 Qiao H, Zhang H, Zheng Y, Ponde DE, Shen D, Gao F, Bakken AB, Schmitz A, Kung HF, Ferrari VA, Zhou R. Embryonic stem cell grafting in normal and infarcted myocardium: serial assessment with MR imaging and PET dual detection. Radiology. 250: 821-9. PMID 19244049 DOI: 10.1148/Radiol.2503080205  0.323
2009 Serdons K, Terwinghe C, Vermaelen P, Van Laere K, Kung H, Mortelmans L, Bormans G, Verbruggen A. Synthesis and evaluation of 18F-labeled 2-phenylbenzothiazoles as positron emission tomography imaging agents for amyloid plaques in Alzheimer's disease. Journal of Medicinal Chemistry. 52: 1428-37. PMID 19216563 DOI: 10.1021/Jm8013376  0.455
2009 Chacko AM, Blankemeyer E, Lieberman BP, Qu W, Kung HF. 5-[18F]Fluoroalkyl pyrimidine nucleosides: probes for positron emission tomography imaging of herpes simplex virus type 1 thymidine kinase gene expression. Nuclear Medicine and Biology. 36: 29-38. PMID 19181266 DOI: 10.1016/J.Nucmedbio.2008.10.009  0.355
2009 Serdons K, Verduyckt T, Vanderghinste D, Cleynhens J, Borghgraef P, Vermaelen P, Terwinghe C, Van Leuven F, Van Laere K, Kung H, Bormans G, Verbruggen A. Synthesis of 18F-labelled 2-(4'-fluorophenyl)-1,3-benzothiazole and evaluation as amyloid imaging agent in comparison with [11C]PIB. Bioorganic & Medicinal Chemistry Letters. 19: 602-5. PMID 19147351 DOI: 10.1016/J.Bmcl.2008.12.069  0.438
2009 Serdons K, Verduyckt T, Vanderghinste D, Borghgraef P, Cleynhens J, Van Leuven F, Kung H, Bormans G, Verbruggen A. 11C-labelled PIB analogues as potential tracer agents for in vivo imaging of amyloid beta in Alzheimer's disease. European Journal of Medicinal Chemistry. 44: 1415-26. PMID 18992967 DOI: 10.1016/J.Ejmech.2008.09.038  0.367
2009 Scott PJ, Hockley BG, Kung HF, Manchanda R, Zhang W, Kilbourn MR. Studies into radiolytic decomposition of fluorine-18 labeled radiopharmaceuticals for positron emission tomography. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 67: 88-94. PMID 18951032 DOI: 10.1016/J.Apradiso.2008.08.015  0.321
2009 Serdons K, Vanderghinste D, Van Eeckhoudt M, Borghgraef P, Kung H, Van Leuven F, De Groot T, Bormans G, Verbruggen A. Synthesis and evaluation of two fluorine-18 labelled phenylbenzothiazoles as potential in vivo tracers for amyloid plaque imaging Journal of Labelled Compounds and Radiopharmaceuticals. 52: 473-481. DOI: 10.1002/Jlcr.1662  0.422
2008 Parhi AK, Kung MP, Ploessl K, Kung HF. Synthesis of Fluorescent Probes based on Stilbenes and Diphenylacetylenes targeting β-Amyloid Plaques. Tetrahedron Letters. 49: 3395-3399. PMID 19122762 DOI: 10.1016/J.Tetlet.2008.03.130  0.306
2008 Kung HF, Lieberman BP, Zhuang ZP, Oya S, Kung MP, Choi SR, Poessl K, Blankemeyer E, Hou C, Skovronsky D, Kilbourn M. In vivo imaging of vesicular monoamine transporter 2 in pancreas using an (18)F epoxide derivative of tetrabenazine. Nuclear Medicine and Biology. 35: 825-37. PMID 19026944 DOI: 10.1016/J.Nucmedbio.2008.08.004  0.425
2008 Chacko AM, Qu W, Kung HF. Synthesis and in vitro evaluation of 5-[(18)f]fluoroalkyl pyrimidine nucleosides for molecular imaging of herpes simplex virus type 1 thymidine kinase reporter gene expression. Journal of Medicinal Chemistry. 51: 5690-701. PMID 18800764 DOI: 10.1021/Jm800501D  0.358
2008 Qu W, Choi SR, Hou C, Zhuang Z, Oya S, Zhang W, Kung MP, Manchandra R, Skovronsky DM, Kung HF. Synthesis and evaluation of indolinyl- and indolylphenylacetylenes as PET imaging agents for beta-amyloid plaques. Bioorganic & Medicinal Chemistry Letters. 18: 4823-7. PMID 18707879 DOI: 10.1016/J.Bmcl.2008.07.077  0.447
2008 Kung MP, Hou C, Lieberman BP, Oya S, Ponde DE, Blankemeyer E, Skovronsky D, Kilbourn MR, Kung HF. In vivo imaging of β-cell mass in rats using 18F-FP-(+)- DTBZ: A potential PET ligand for studying diabetes mellitus Journal of Nuclear Medicine. 49: 1171-1176. PMID 18552132 DOI: 10.2967/Jnumed.108.051680  0.405
2008 Wang JL, Parhi AK, Oya S, Lieberman B, Kung MP, Kung HF. 2-(2'-((Dimethylamino)methyl)-4'-(3-[(18)F]fluoropropoxy)-phenylthio)benzenamine for positron emission tomography imaging of serotonin transporters. Nuclear Medicine and Biology. 35: 447-58. PMID 18482682 DOI: 10.1016/J.Nucmedbio.2008.02.009  0.562
2008 Song PJ, Bernard S, Sarradin P, Vergote J, Barc C, Chalon S, Kung MP, Kung HF, Guilloteau D. IMPY, a potential beta-amyloid imaging probe for detection of prion deposits in scrapie-infected mice. Nuclear Medicine and Biology. 35: 197-201. PMID 18312829 DOI: 10.1016/J.Nucmedbio.2007.10.005  0.332
2008 Plössl K, Chandra R, Qu W, Lieberman BP, Kung MP, Zhou R, Huang B, Kung HF. A novel gallium bisaminothiolate complex as a myocardial perfusion imaging agent. Nuclear Medicine and Biology. 35: 83-90. PMID 18158947 DOI: 10.1016/J.Nucmedbio.2007.08.002  0.348
2008 Lakshmi B, Kung MP, Lieberman B, Zhao J, Waterhouse R, Kung HF. (R)-N-Methyl-3-(3-(125)I-pyridin-2-yloxy)-3-phenylpropan-1-amine: a novel probe for norepinephrine transporters. Nuclear Medicine and Biology. 35: 43-52. PMID 18158942 DOI: 10.1016/J.Nucmedbio.2007.08.007  0.417
2008 Maezawa I, Hong HS, Liu R, Wu CY, Cheng RH, Kung MP, Kung HF, Lam KS, Oddo S, Laferla FM, Jin LW. Congo red and thioflavin-T analogs detect Abeta oligomers. Journal of Neurochemistry. 104: 457-68. PMID 17953662 DOI: 10.1111/J.1471-4159.2007.04972.X  0.385
2007 Parhi AK, Wang JL, Oya S, Choi SR, Kung MP, Kung HF. 2-(2'-((dimethylamino)methyl)-4'-(fluoroalkoxy)-phenylthio)benzenamine derivatives as serotonin transporter imaging agents. Journal of Medicinal Chemistry. 50: 6673-84. PMID 18052090 DOI: 10.1021/Jm070685E  0.612
2007 Kung HF, Kung MP, Wey SP, Lin KJ, Yen TC. Clinical acceptance of a molecular imaging agent: a long march with [99mTc]TRODAT. Nuclear Medicine and Biology. 34: 787-9. PMID 17921030 DOI: 10.1016/J.Nucmedbio.2007.03.010  0.331
2007 Qu W, Kung MP, Hou C, Oya S, Kung HF. Quick assembly of 1,4-diphenyltriazoles as probes targeting beta-amyloid aggregates in Alzheimer's disease. Journal of Medicinal Chemistry. 50: 3380-7. PMID 17569520 DOI: 10.1021/Jm070467L  0.387
2007 Qu W, Kung MP, Hou C, Jin LW, Kung HF. Radioiodinated aza-diphenylacetylenes as potential SPECT imaging agents for beta-amyloid plaque detection. Bioorganic & Medicinal Chemistry Letters. 17: 3581-4. PMID 17502139 DOI: 10.1016/J.Bmcl.2007.04.062  0.407
2007 Chandra R, Oya S, Kung MP, Hou C, Jin LW, Kung HF. New diphenylacetylenes as probes for positron emission tomographic imaging of amyloid plaques. Journal of Medicinal Chemistry. 50: 2415-23. PMID 17447752 DOI: 10.1021/Jm070090J  0.396
2007 Qu W, Kung MP, Hou C, Benedum TE, Kung HF. Novel styrylpyridines as probes for SPECT imaging of amyloid plaques. Journal of Medicinal Chemistry. 50: 2157-65. PMID 17411026 DOI: 10.1021/Jm070025+  0.385
2007 Kung MP, Hou C, Goswami R, Ponde DE, Kilbourn MR, Kung HF. Characterization of optically resolved 9-fluoropropyl-dihydrotetrabenazine as a potential PET imaging agent targeting vesicular monoamine transporters Nuclear Medicine and Biology. 34: 239-246. PMID 17383573 DOI: 10.1016/J.Nucmedbio.2006.12.005  0.442
2007 Kilbourn MR, Hockley B, Lee L, Hou C, Goswami R, Ponde DE, Kung MP, Kung HF. Pharmacokinetics of [18F]fluoroalkyl derivatives of dihydrotetrabenazine in rat and monkey brain Nuclear Medicine and Biology. 34: 233-237. PMID 17383572 DOI: 10.1016/J.Nucmedbio.2007.01.007  0.406
2007 Oya S, Choi SR, Kung MP, Kung HF. 5-Chloro-2-(2'-((dimethylamino)methyl)-4'-iodophenylthio)benzenamine: a new serotonin transporter ligand. Nuclear Medicine and Biology. 34: 129-39. PMID 17307121 DOI: 10.1016/J.Nucmedbio.2006.12.002  0.439
2007 Stephenson KA, Chandra R, Zhuang ZP, Hou C, Oya S, Kung MP, Kung HF. Fluoro-pegylated (FPEG) imaging agents targeting Abeta aggregates. Bioconjugate Chemistry. 18: 238-46. PMID 17226978 DOI: 10.1021/Bc060239Q  0.416
2007 Zhang W, Kung MP, Oya S, Hou C, Kung HF. 18F-labeled styrylpyridines as PET agents for amyloid plaque imaging. Nuclear Medicine and Biology. 34: 89-97. PMID 17210465 DOI: 10.1016/J.Nucmedbio.2006.10.003  0.464
2006 Goswami R, Ponde DE, Kung MP, Hou C, Kilbourn MR, Kung HF. Fluoroalkyl derivatives of dihydrotetrabenazine as positron emission tomography imaging agents targeting vesicular monoamine transporters Nuclear Medicine and Biology. 33: 685-694. PMID 16934687 DOI: 10.1016/J.Nucmedbio.2006.05.006  0.441
2006 Zhuang ZP, Kung MP, Kung HF. Synthesis of biphenyltrienes as probes for beta-amyloid plaques. Journal of Medicinal Chemistry. 49: 2841-4. PMID 16640346 DOI: 10.1021/Jm051020K  0.376
2006 Ono M, Kawashima H, Nonaka A, Kawai T, Haratake M, Mori H, Kung MP, Kung HF, Saji H, Nakayama M. Novel benzofuran derivatives for PET imaging of beta-amyloid plaques in Alzheimer's disease brains. Journal of Medicinal Chemistry. 49: 2725-30. PMID 16640332 DOI: 10.1021/Jm051176K  0.406
2006 Hou C, Tu Z, Mach R, Kung HF, Kung MP. Characterization of a novel iodinated sigma-2 receptor ligand as a cell proliferation marker. Nuclear Medicine and Biology. 33: 203-9. PMID 16546674 DOI: 10.1016/J.Nucmedbio.2005.10.001  0.362
2006 Chandra R, Kung MP, Kung HF. Design, synthesis, and structure-activity relationship of novel thiophene derivatives for beta-amyloid plaque imaging. Bioorganic & Medicinal Chemistry Letters. 16: 1350-2. PMID 16325402 DOI: 10.1016/J.Bmcl.2005.11.055  0.389
2006 Clark CM, Newberg AB, Watson M, Wintering NA, Skovronsky DM, Kung HF. P2-343: Imaging amyloid with I123 IMPY SPECT Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1183  0.336
2005 Zhang W, Oya S, Kung MP, Hou C, Maier DL, Kung HF. F-18 Polyethyleneglycol stilbenes as PET imaging agents targeting Abeta aggregates in the brain. Nuclear Medicine and Biology. 32: 799-809. PMID 16253804 DOI: 10.1016/J.Nucmedbio.2005.06.001  0.457
2005 Kung MP, Kung HF. Mass effect of injected dose in small rodent imaging by SPECT and PET. Nuclear Medicine and Biology. 32: 673-8. PMID 16243641 DOI: 10.1016/J.Nucmedbio.2005.04.002  0.382
2005 Zhang W, Oya S, Kung MP, Hou C, Maier DL, Kung HF. F-18 stilbenes as PET imaging agents for detecting beta-amyloid plaques in the brain. Journal of Medicinal Chemistry. 48: 5980-8. PMID 16162001 DOI: 10.1021/Jm050166G  0.416
2005 Choi SR, Zhuang ZP, Chacko AM, Acton PD, Tjuvajev-Gelovani J, Doubrovin M, Chu DC, Kung HF. SPECT imaging of herpes simplex virus type1 thymidine kinase gene expression by [(123)I]FIAU(1). Academic Radiology. 12: 798-805. PMID 16039533 DOI: 10.1016/J.Acra.2005.04.010  0.308
2005 Ono M, Haratake M, Nakayama M, Kaneko Y, Kawabata K, Mori H, Kung MP, Kung HF. Synthesis and biological evaluation of (E)-3-styrylpyridine derivatives as amyloid imaging agents for Alzheimer's disease. Nuclear Medicine and Biology. 32: 329-35. PMID 15878502 DOI: 10.1016/J.Nucmedbio.2005.01.006  0.4
2005 Zhuang ZP, Kung MP, Hou C, Ploessl K, Kung HF. Biphenyls labeled with technetium 99m for imaging beta-amyloid plaques in the brain. Nuclear Medicine and Biology. 32: 171-84. PMID 15721763 DOI: 10.1016/J.Nucmedbio.2004.10.002  0.393
2005 Kung M, Hou C, Zhuang Z, Skovronsky D, Kung HF. Erratum to “Binding of two potential imaging agents targeting amyloid plaques in postmortem brain tissues of patients with Alzheimer's disease” [Brain Research 1025 (2004) 98–105] Brain Research. 1031: 302. DOI: 10.1016/J.Brainres.2004.10.002  0.361
2004 Verhoeff NP, Wilson AA, Takeshita S, Trop L, Hussey D, Singh K, Kung HF, Kung MP, Houle S. In-vivo imaging of Alzheimer disease beta-amyloid with [11C]SB-13 PET. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 12: 584-95. PMID 15545326 DOI: 10.1176/Appi.Ajgp.12.6.584  0.351
2004 Kung MP, Hou C, Zhuang ZP, Skovronsky D, Kung HF. Binding of two potential imaging agents targeting amyloid plaques in postmortem brain tissues of patients with Alzheimer's disease Brain Research. 1025: 98-105. PMID 15464749 DOI: 10.1016/J.Brainres.2004.08.004  0.412
2004 Kung HF, Newman S, Choi SR, Oya S, Hou C, Zhuang ZP, Acton PD, Plössl K, Winkler J, Kung MP. 2-(2-(dimethylaminomethyl)phenoxy)-5-iodophenylamine: An improved serotonin transporter imaging agent Journal of Medicinal Chemistry. 47: 5258-5264. PMID 15456270 DOI: 10.1021/Jm049917P  0.414
2004 Choi H, Choi SR, Zhou R, Kung HF, Chen IW. Iron oxide nanoparticles as magnetic resonance contrast agent for tumor imaging via folate receptor-targeted delivery. Academic Radiology. 11: 996-1004. PMID 15350580 DOI: 10.1016/J.Acra.2004.04.018  0.3
2004 Kung MP, Zhuang ZP, Hou C, Kung HF. Development and evaluation of iodinated tracers targeting amyloid plaques for SPECT imaging. Journal of Molecular Neuroscience : Mn. 24: 49-53. PMID 15314249 DOI: 10.1385/Jmn:24:1:049  0.395
2004 Kung MP, Choi SR, Hou C, Zhuang ZP, Foulon C, Kung HF. Selective binding of 2-[125I]iodo-nisoxetine to norepinephrine transporters in the brain. Nuclear Medicine and Biology. 31: 533-41. PMID 15219270 DOI: 10.1016/J.Nucmedbio.2004.03.001  0.398
2004 Kung MP, Hou C, Zhuang ZP, Cross AJ, Maier DL, Kung HF. Characterization of IMPY as a potential imaging agent for beta-amyloid plaques in double transgenic PSAPP mice. European Journal of Nuclear Medicine and Molecular Imaging. 31: 1136-45. PMID 15007564 DOI: 10.1007/S00259-004-1487-Z  0.398
2004 Acton PD, Kung HF. Small animal imaging with high resolution single photon emission tomography. Nuclear Medicine and Biology. 30: 889-95. PMID 14698793 DOI: 10.1016/S0969-8051(03)00112-4  0.359
2004 Lee CW, Kung MP, Hou C, Kung HF. Dimethylamino-fluorenes: ligands for detecting beta-amyloid plaques in the brain. Nuclear Medicine and Biology. 30: 573-80. PMID 12900283 DOI: 10.1016/S0969-8051(03)00050-7  0.414
2004 Ono M, Wilson A, Nobrega J, Westaway D, Verhoeff P, Zhuang ZP, Kung MP, Kung HF. 11C-labeled stilbene derivatives as Abeta-aggregate-specific PET imaging agents for Alzheimer's disease. Nuclear Medicine and Biology. 30: 565-71. PMID 12900282 DOI: 10.1016/S0969-8051(03)00049-0  0.413
2004 Hou C, Kung M, Xiu Y, Skovronsky DM, Mach R, Kung HF. P2-188 Labeling amyloid plaque-like structures by radioiodinated ligands in rhesus monkey brain Neurobiology of Aging. 25: S281. DOI: 10.1016/S0197-4580(04)80934-5  0.328
2004 Kung HF, Kung M, Zhuang Z, Lee C, Hou C. P2-151 Biphenyl derivatives as specific binding agents for Aβ aggregates Neurobiology of Aging. 25: S268. DOI: 10.1016/S0197-4580(04)80898-4  0.301
2004 Verhoeff NP, Wilson AA, Nobrega J, Westaway D, George-Hyslop PS, Hussey D, Takeshita S, Trop L, Singh K, Kung HF, Kung M, Houle S. O3-03-07 [11C]SB-13 PET: a valid alternative for β-amyloid imaging in vivo? Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80197-0  0.323
2004 Kung M, Hou C, Zhuang Z, Skovronsky DM, Kung HF. O3-03-02 Binding of two potential imaging agents targeting amyloid plaques in Alzheimer's disease brains Neurobiology of Aging. 25: S57. DOI: 10.1016/S0197-4580(04)80192-1  0.374
2004 Wilson AA, Garcia A, Chestakova A, Kung H, Houle S. A rapid one-step radiosynthesis of theβ-amyloid imaging radiotracerN-methyl-[11C]2-(4′-methylaminophenyl)-6-hydroxybenzothiazole([11C]-6-OH-BTA-1) Journal of Labelled Compounds and Radiopharmaceuticals. 47: 679-682. DOI: 10.1002/Jlcr.854  0.316
2004 Stoll T, Ermert J, Oya S, Kung HF, Coenen HH. Application of n.c.a. 4-[18F]fluorophenol in diaryl ether syntheses of 2-(4-[18F]fluorophenoxy)-benzylamines Journal of Labelled Compounds and Radiopharmaceuticals. 47: 443-455. DOI: 10.1002/Jlcr.828  0.369
2003 Kung MP, Zhuang ZP, Hou C, Jin LW, Kung HF. Characterization of radioiodinated ligand binding to amyloid beta plaques. Journal of Molecular Neuroscience : Mn. 20: 249-54. PMID 14501004 DOI: 10.1385/Jmn:20:3:249  0.384
2003 Kung MP, Skovronsky DM, Hou C, Zhuang ZP, Gur TL, Zhang B, Trojanowski JQ, Lee VM, Kung HF. Detection of amyloid plaques by radioligands for Abeta40 and Abeta42: potential imaging agents in Alzheimer's patients. Journal of Molecular Neuroscience : Mn. 20: 15-24. PMID 12663930 DOI: 10.1385/Jmn:20:1:15  0.339
2003 Auricchio A, Acton PD, Hildinger M, Louboutin JP, Plössl K, O'Connor E, Kung HF, Wilson JM. In vivo quantitative noninvasive imaging of gene transfer by single-photon emission computerized tomography. Human Gene Therapy. 14: 255-61. PMID 12639305 DOI: 10.1089/10430340360535805  0.346
2003 Kung HF, Kung MP, Choi SR. Radiopharmaceuticals for single-photon emission computed tomography brain imaging Seminars in Nuclear Medicine. 33: 2-13. PMID 12605353 DOI: 10.1053/Snuc.2003.127296  0.426
2003 Zhuang ZP, Kung MP, Wilson A, Lee CW, Plössl K, Hou C, Holtzman DM, Kung HF. Structure-activity relationship of imidazo[1,2-a]pyridines as ligands for detecting beta-amyloid plaques in the brain. Journal of Medicinal Chemistry. 46: 237-43. PMID 12519062 DOI: 10.1021/Jm020351J  0.386
2002 Acton PD, Hou C, Kung M, Plössl K, Keeney CL, Kung HF. Occupancy of dopamine D2 receptors in the mouse brain measured using ultra-high-resolution single-photon emission tomography and [123I]IBF European Journal of Nuclear Medicine and Molecular Imaging. 29: 1507-1515. PMID 12537007 DOI: 10.1007/S00259-002-0903-5  0.361
2002 Kung MP, Hou C, Zhuang ZP, Zhang B, Skovronsky D, Trojanowski JQ, Lee VMY, Kung HF. IMPY: An improved thioflavin-T derivative for in vivo labeling of β-amyloid plaques Brain Research. 956: 202-210. PMID 12445687 DOI: 10.1016/S0006-8993(02)03436-4  0.38
2002 Oya S, Choi SR, Coenen H, Kung HF. New PET imaging agent for the serotonin transporter: [(18)F]ACF (2-[(2-amino-4-chloro-5-fluorophenyl)thio]-N,N-dimethyl-benzenmethanamine). Journal of Medicinal Chemistry. 45: 4716-23. PMID 12361398 DOI: 10.1021/Jm020167Y  0.456
2002 Ono M, Kung MP, Hou C, Kung HF. Benzofuran derivatives as Aβ-aggregate-specific imaging agents for Alzheimer's disease Nuclear Medicine and Biology. 29: 633-642. PMID 12234587 DOI: 10.1016/S0969-8051(02)00326-8  0.414
2002 Kung MP, Hou C, Zhuang ZP, Skovronsky DM, Zhang B, Gur TL, Trojanowski JQ, Lee VM, Kung HF. Radioiodinated styrylbenzene derivatives as potential SPECT imaging agents for amyloid plaque detection in Alzheimer's disease. Journal of Molecular Neuroscience : Mn. 19: 7-10. PMID 12212796 DOI: 10.1007/S12031-002-0003-9  0.348
2002 Acton PD, Kung M, Hou C, Plössl K, Keeney C, Kung HF. Ultra-high resolution single photon emission tomography imaging of the mouse striatum European Journal of Nuclear Medicine and Molecular Imaging. 29: 446-446. PMID 12002724 DOI: 10.1007/S00259-002-0770-0  0.363
2002 Acton PD, Choi S, Plössl K, Kung HF. Quantification of dopamine transporters in the mouse brain using ultra-high resolution single-photon emission tomography European Journal of Nuclear Medicine and Molecular Imaging. 29: 691-698. PMID 11976810 DOI: 10.1007/S00259-002-0776-7  0.372
2001 Zhuang ZP, Kung MP, Hou C, Plössl K, Skovronsky D, Gur TL, Trojanowski JQ, Lee VM, Kung HF. IBOX(2-(4'-dimethylaminophenyl)-6-iodobenzoxazole): a ligand for imaging amyloid plaques in the brain. Nuclear Medicine and Biology. 28: 887-94. PMID 11711307 DOI: 10.1016/S0969-8051(01)00264-5  0.41
2001 Schmidt ML, Schuck T, Sheridan S, Kung MP, Kung H, Zhuang ZP, Bergeron C, Lamarche JS, Skovronsky D, Giasson BI, Lee VM, Trojanowski JQ. The fluorescent Congo red derivative, (trans, trans)-1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene (BSB), labels diverse beta-pleated sheet structures in postmortem human neurodegenerative disease brains. The American Journal of Pathology. 159: 937-43. PMID 11549586 DOI: 10.1016/S0002-9440(10)61769-5  0.37
2001 Choi SR, Yang B, Plössl K, Chumpradit S, Wey SP, Acton PD, Wheeler K, Mach RH, Kung HF. Development of a Tc-99m labeled sigma-2 receptor-specific ligand as a potential breast tumor imaging agent Nuclear Medicine and Biology. 28: 657-666. PMID 11518647 DOI: 10.1016/S0969-8051(01)00234-7  0.365
2001 Kung HF. Development of Tc-99m labeled tropanes: TRODAT-1, as a dopamine transporter imaging agent Nuclear Medicine and Biology. 28: 505-508. PMID 11516695 DOI: 10.1016/S0969-8051(01)00220-7  0.359
2001 Lee CW, Zhuang ZP, Kung MP, Plössl K, Skovronsky D, Gur T, Hou C, Trojanowski JQ, Lee VMY, Kung HF. Isomerization of (Z,Z) to (E,E)1-bromo-2,5-bis-(3- hydroxycarbonyl-4-hydroxy)-styrylbenzene in strong base: Probes for amyloid plaques in the brain Journal of Medicinal Chemistry. 44: 2270-2275. PMID 11428920 DOI: 10.1021/Jm010161T  0.305
2001 Zhuang ZP, Kung MP, Hou C, Skovronsky DM, Gur TL, Plössl K, Trojanowski JQ, Lee VM, Kung HF. Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates. Journal of Medicinal Chemistry. 44: 1905-14. PMID 11384236 DOI: 10.1021/Jm010045Q  0.353
2001 Mach RH, Wheeler KT, Blair S, Yang B, Day CS, Blair JB, Choi SR, Kung HF. Preparation of a technetium-99m SPECT agent for imaging the sigma-2 receptor status of solid tumors Journal of Labelled Compounds and Radiopharmaceuticals. 44: 899-908. DOI: 10.1002/Jlcr.516  0.392
2001 Zhuang Z, Kung M, Hou C, Lee C, Trojanowski JQ, Lee VM, Kung HF. Radioiodinated styrylbenzene derivatives as probes for imaging amyloid Journal of Labelled Compounds and Radiopharmaceuticals. 44: S236-S238. DOI: 10.1002/Jlcr.2580440182  0.338
2001 Chumpradit S, Choi SR, Zhuang Z, Kung HF. A novel iodinated benzamide derivative for imaging endogenous dopamine Journal of Labelled Compounds and Radiopharmaceuticals. 44: S225-S227. DOI: 10.1002/Jlcr.2580440178  0.337
2001 Chumpradit S, Choi SR, Hou C, Acton PD, Kung HF. Novel TC-99M N2S2 derivatives for imaging 5HT2A receptors Journal of Labelled Compounds and Radiopharmaceuticals. 44: S524-S526. DOI: 10.1002/Jlcr.25804401186  0.317
2001 Zhuang Z, Kung M, Hou C, Lee C, Trojanowski JQ, Lee VM, Kung HF. Novel probes for imaging amyloid: Iodinated benzothiazole derivatives Journal of Labelled Compounds and Radiopharmaceuticals. 44: S29-S32. DOI: 10.1002/Jlcr.2580440111  0.347
2001 Oya S, Choi S, Hou C, Kung M, Acton PD, Shiue C, Kung HF. Synthesis and characterization of 18F-IDAM as a pet imaging agent for serotonin transporters Journal of Labelled Compounds and Radiopharmaceuticals. 44: S15-S17. DOI: 10.1002/Jlcr.2580440106  0.414
2000 Dresel S, Krause J, Krause K-, LaFougere C, Brinkbäumer K, Kung HF, Hahn K, Tatsch K. Attention deficit hyperactivity disorder: binding of [99mTc]TRODAT-1 to the dopamine transporter before and after methylphenidate treatment European Journal of Nuclear Medicine and Molecular Imaging. 27: 1518-1524. PMID 11083541 DOI: 10.1007/S002590000330  0.301
2000 Choi SR, Hou C, Oya S, Mu M, Kung MP, Siciliano M, Acton PD, Kung HF. Selective in vitro and in vivo binding of [(125)I]ADAM to serotonin transporters in rat brain. Synapse (New York, N.Y.). 38: 403-12. PMID 11044887 DOI: 10.1002/1098-2396(20001215)38:4<403::Aid-Syn5>3.0.Co;2-Z  0.402
2000 Skovronsky DM, Zhang B, Kung MP, Kung HF, Trojanowski JQ, Lee VM. In vivo detection of amyloid plaques in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 97: 7609-14. PMID 10861023 DOI: 10.1073/Pnas.97.13.7609  0.333
2000 Oya S, Choi SR, Hou C, Mu M, Kung MP, Acton PD, Siciliano M, Kung HF. 2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine (ADAM): an improved serotonin transporter ligand. Nuclear Medicine and Biology. 27: 249-54. PMID 10832081 DOI: 10.1016/S0969-8051(00)00084-6  0.434
2000 Krause KH, Dresel SH, Krause J, Kung HF, Tatsch K. Increased striatal dopamine transporter in adult patients with attention deficit hyperactivity disorder: effects of methylphenidate as measured by single photon emission computed tomography. Neuroscience Letters. 285: 107-10. PMID 10793238 DOI: 10.1016/S0304-3940(00)01040-5  0.306
2000 Zhuang Z, Choi S, Hou C, Mu M, Kung M, Acton PD, Kung HF. A novel serotonin transporter ligand: (5-iodo-2-(2-dimethylaminomethylphenoxy)-benzyl alcohol. Nuclear Medicine and Biology. 27: 169-75. PMID 10773546 DOI: 10.1016/S0969-8051(99)00093-1  0.426
2000 Xu Y, Choi SR, Kung MP, Kung HF. Synthesis of radioiodinated 1-deoxy-nojirimycin derivatives: novel glucose analogs. Nuclear Medicine and Biology. 26: 833-9. PMID 10628565 DOI: 10.1016/S0969-8051(99)00063-3  0.382
2000 Mu M, Kung MP, Plössl K, Acton PD, Mozley PD, Kung HF. A simplified method to determine [99mTc]TRODAT-1 in human plasma. Nuclear Medicine and Biology. 26: 821-5. PMID 10628563 DOI: 10.1016/S0969-8051(99)00065-7  0.325
1999 Acton PD, Mu M, Plössl K, Hou C, Siciliano M, Zhuang Z, Oya S, Choi S, Kung HF. Single-photon emission tomography imaging of serotonin transporters in the nonhuman primate brain with [(123)I]ODAM. European Journal of Nuclear Medicine and Molecular Imaging. 26: 1359-1362. PMID 10541838 DOI: 10.1007/S002590050596  0.418
1999 Acton PD, Kung M, Mu M, Plössl K, Hou C, Siciliano M, Oya S, Kung HF. Single-photon emission tomography imaging of serotonin transporters in the non-human primate brain with the selective radioligand [(123)I]IDAM. European Journal of Nuclear Medicine and Molecular Imaging. 26: 854-861. PMID 10436198 DOI: 10.1007/S002590050459  0.424
1999 Kung MP, Hou C, Oya S, Mu M, Acton PD, Kung HF. Characterization of [(123)I]IDAM as a novel single-photon emission tomography tracer for serotonin transporters. European Journal of Nuclear Medicine. 26: 844-53. PMID 10436197 DOI: 10.1007/S002590050458  0.411
1999 Choi SR, Kung MP, Plössl K, Meegalla S, Kung HF. An improved kit formulation of a dopamine transporter imaging agent: [Tc-99m]TRODAT-1. Nuclear Medicine and Biology. 26: 461-6. PMID 10382851 DOI: 10.1016/S0969-8051(99)00010-4  0.372
1999 Acton PD, Pilowsky LS, Kung HF, Ell PJ. Automatic segmentation of dynamic neuroreceptor single-photon emission tomography images using fuzzy clustering. European Journal of Nuclear Medicine. 26: 581-90. PMID 10369943 DOI: 10.1007/S002590050425  0.347
1999 Dresel SHJ, Kung MT, Huang X, Plössl K, Hou C, Shiue CY, Karp J, Kung HF. In vivo imaging of serotonin transporters with [99mTc]TRODAT-1 in nonhuman primates. European Journal of Nuclear Medicine and Molecular Imaging. 26: 342-347. PMID 10199939 DOI: 10.1007/S002590050396  0.416
1999 Oya S, Kung MP, Acton PD, Mu M, Hou C, Kung HF. A new single-photon emission computed tomography imaging agent for serotonin transporters: [123I]IDAM, 5-iodo-2-((2-((dimethylamino)methyl)phenyl)thio)benzyl alcohol. Journal of Medicinal Chemistry. 42: 333-5. PMID 9986702 DOI: 10.1021/Jm9806751  0.326
1998 Meegalla SK, Plössl K, Kung MP, Stevenson DA, Mu M, Kushner S, Liable-Sands LM, Rheingold AL, Kung HF. Specificity of diastereomers of [99mTc]TRODAT-1 as dopamine transporter imaging agents. Journal of Medicinal Chemistry. 41: 428-36. PMID 9484494 DOI: 10.1021/Jm970742B  0.334
1998 Oya S, Plössl K, Kung MP, Stevenson DA, Kung HF. Small and neutral Tc(v)O BAT, bisaminoethanethiol (N2S2) complexes for developing new brain imaging agents. Nuclear Medicine and Biology. 25: 135-40. PMID 9468028 DOI: 10.1016/S0969-8051(97)00153-4  0.372
1998 Zhuang ZP, Kung MP, Mu M, Kung HF. Isoindol-1-one analogues of 4-(2'-methoxyphenyl)-1-[2'-[N-(2'-pyridyl)- p-iodobenzamido]ethyl]piperazine (p-MPPI) as 5-HT1(A) receptor ligands Journal of Medicinal Chemistry. 41: 157-166. PMID 9457239 DOI: 10.1021/Jm970296S  0.375
1998 Kung HF, Meegalla S, Kung M, Plössl K. Transition Metal Chemistry. 23: 531-536. DOI: 10.1023/A:1006921811871  0.379
1997 Vessotskie JM, Kung MP, Chumpradit S, Kung HF. Quantitative autoradiographic studies of dopamine D3 receptors in rat cerebellum using [125I]S(-)5-OH-PIPAT Brain Research. 778: 89-98. PMID 9462880 DOI: 10.1016/S0006-8993(97)01014-7  0.339
1997 Dresel SHJ, Kung M, Plössl K, Meegalla SK, Kung HF. Pharmacological effects of dopaminergic drugs on in vivo binding of [99mTc]TRODAT-1 to the central dopamine transporters in rats. European Journal of Nuclear Medicine and Molecular Imaging. 25: 31-39. PMID 9396872 DOI: 10.1007/S002590050191  0.352
1997 Vessotskie JM, Kung MP, Chumpradit S, Kung HF. Characterization of [125I]S(-)5-OH-PIPAT binding to dopamine d2-like receptors expressed in cell lines Neuropharmacology. 36: 999-1007. PMID 9257944 DOI: 10.1016/S0028-3908(97)00076-2  0.333
1997 al-Tikriti MS, Baldwin RM, Zea-Ponce Y, Sybirska E, Zoghbi SS, Laruelle M, Malison RT, Kung HF, Kessler RM, Charney DS. Comparison of three high affinity SPECT radiotracers for the dopamine D2 receptor. Nuclear Medicine and Biology. 21: 179-88. PMID 9234281 DOI: 10.1016/0969-8051(94)90007-8  0.367
1997 Tatsch K, Schwarz J, Mozley PD, Linke R, Pogarell O, Oertel WH, Fieber RS, Hahn K, Kung HF. Relationship between clinical features of Parkinson's disease and presynaptic dopamine transporter binding assessed with [123I]IPT and single-photon emission tomography. European Journal of Nuclear Medicine. 24: 415-21. PMID 9096093 DOI: 10.1007/Bf00881814  0.326
1997 Kung MP, Stevenson DA, Plössl K, Meegalla SK, Beckwith A, Essman WD, Mu M, Lucki I, Kung HF. [99mTc]TRODAT-1: a novel technetium-99m complex as a dopamine transporter imaging agent. European Journal of Nuclear Medicine. 24: 372-80. PMID 9096087 DOI: 10.1007/Bf00881808  0.413
1997 Shiue CY, Shiue GG, Mozley PD, Kung MP, Zhuang ZP, Kim HJ, Kung HF. P-[18F]-MPPF: a potential radioligand for PET studies of 5-HT1A receptors in humans. Synapse (New York, N.Y.). 25: 147-54. PMID 9021895 DOI: 10.1002/(Sici)1098-2396(199702)25:2<147::Aid-Syn5>3.0.Co;2-C  0.417
1997 Meegalla SK, Plössl K, Kung MP, Chumpradit S, Stevenson DA, Kushner SA, McElgin WT, Mozley PD, Kung HF. Synthesis and characterization of technetium-99m-labeled tropanes as dopamine transporter-imaging agents. Journal of Medicinal Chemistry. 40: 9-17. PMID 9016323 DOI: 10.1021/jm960532j  0.327
1997 Pellevoisin C, Chalon S, Kung HF, Besnard JC, Guilloteau D. Is TISCH a suitable tracer for in vivo study of modifications of the dopamine D-1 receptor? Nuclear Medicine and Biology. 23: 75-8. PMID 9004918 DOI: 10.1016/0969-8051(95)02070-5  0.356
1997 Kung MP, Stevenson DA, Zhuang ZP, Vessotskie JM, Chumpradit S, Sun XM, Kung HF. Characterization of a novel iodinated ligand, IPMPP, for human dopamine D4 receptors expressed in CHO cells. Life Sciences. 60: 91-100. PMID 9000114 DOI: 10.1016/S0024-3205(96)00598-X  0.353
1997 Laruelle M, Iyer RN, al-Tikriti MS, Zea-Ponce Y, Malison R, Zoghbi SS, Baldwin RM, Kung HF, Charney DS, Hoffer PB, Innis RB, Bradberry CW. Microdialysis and SPECT measurements of amphetamine-induced dopamine release in nonhuman primates. Synapse (New York, N.Y.). 25: 1-14. PMID 8987142 DOI: 10.1002/(Sici)1098-2396(199701)25:1<1::Aid-Syn1>3.0.Co;2-H  0.345
1997 Kung HF, Kim HJ, Kung MP, Meegalla SK, Plössl K, Lee HK. Imaging of dopamine transporters in humans with technetium-99m TRODAT-1. European Journal of Nuclear Medicine. 23: 1527-30. PMID 8854853 DOI: 10.1007/Bf01254479  0.346
1996 Mach RH, Nader MA, Ehrenkaufer RL, Line SW, Smith CR, Luedtke RR, Kung MP, Kung HF, Lyons D, Morton TE. Comparison of two fluorine-18 labeled benzamide derivatives that bind reversibly to dopamine D2 receptors: in vitro binding studies and positron emission tomography. Synapse (New York, N.Y.). 24: 322-33. PMID 10638823 DOI: 10.1002/(Sici)1098-2396(199612)24:4<322::Aid-Syn2>3.0.Co;2-F  0.403
1996 Kung HF, Frederick D, Kim HJ, McElgin W, Kung MP, Mu M, Mozley PD, Vessotskie JM, Stevenson DA, Kushner SA, Zhuang ZP. In vivo SPECT imaging of 5-HT1A receptors with [123I]p-MPPI in nonhuman primates. Synapse (New York, N.Y.). 24: 273-81. PMID 8923668 DOI: 10.1002/(Sici)1098-2396(199611)24:3<273::Aid-Syn10>3.0.Co;2-Y  0.372
1996 Kung HF, Stevenson DA, Zhuang ZP, Kung MP, Frederick D, Hurt SD. New 5-HT1A receptor antagonist: [3H]p-MPPF. Synapse (New York, N.Y.). 23: 344-6. PMID 8855520 DOI: 10.1002/(Sici)1098-2396(199608)23:4<344::Aid-Syn13>3.0.Co;2-X  0.328
1996 Meegalla S, Plössl K, Kung MP, Chumpradit S, Stevenson DA, Frederick D, Kung HF. Tc-99m-labeled tropanes as dopamine transporter imaging agents. Bioconjugate Chemistry. 7: 421-9. PMID 8853455 DOI: 10.1021/Bc960029L  0.406
1996 Kim HJ, Karp JS, Mozley PD, Yang SO, Moon DH, Kung HF, Lee HK, Alavi A. Stimulating technetium-99m cerebral perfusion studies with a three-dimensional Hoffmann brain phantom: collimator and filter selection in SPECT neuroimaging. Annals of Nuclear Medicine. 10: 153-60. PMID 8814722 DOI: 10.1007/Bf03165071  0.31
1995 Kung MP, Mu M, Zhuang ZP, Kung HF. NCS-MPP (4-(2′-METHOXY-PHENYL)-1-[2′-(N-2″-PYRIDYL)-P-Isothiocyanobenzamido]-Ethyl-Piperazine): A high affinity and irreversible 5-HT1A receptor ligand Life Sciences. 58: 177-186. PMID 9499158 DOI: 10.1016/0024-3205(95)02275-9  0.339
1995 Oya S, Kung MP, Frederick D, Kung HF. New bisaminoethanethiol (BAT) ligands which form two interconvertible Tc-99m complexes. Nuclear Medicine and Biology. 22: 749-57. PMID 8535335 DOI: 10.1016/0969-8051(95)00021-O  0.309
1995 Laruelle M, al-Tikriti MS, Zea-Ponce Y, Zoghbi SS, Baldwin RM, Charney DS, Hoffer PB, Kung HF, Innis RB. In vivo quantification of dopamine D2 receptor parameters in nonhuman primates with [123I]iodobenzofuran and single photon emission computerized tomography. European Journal of Pharmacology. 263: 39-51. PMID 7821360 DOI: 10.1016/0014-2999(94)90521-5  0.361
1995 Zhuang ZP, Kung MP, Chumpradit S, Mu M, Kung HF. Derivatives of 4-(2'-methoxyphenyl)-1-[2'-(N-2"-pyridinyl-p-iodobenzamido)ethyl]pipera zine (p-MPPI) as 5-HT1A ligands. Journal of Medicinal Chemistry. 37: 4572-5. PMID 7799409 DOI: 10.1021/Jm00052A018  0.324
1995 Zhuang ZP, Kung MP, Clarke W, Maayani S, Mu M, Kung HF. Synthesis of (+)-(R)- and (-)-(S)-trans-8-hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-propenyl)] aminotetralin: new 5-HT1A receptor ligands. Chirality. 7: 452-8. PMID 7577352 DOI: 10.1002/Chir.530070611  0.301
1995 Canney DJ, Kung MP, Kung HF. Amino- and amido-tetrabenazine derivatives: Synthesis and evaluation as potential ligands for the vesicular monoamine transporter Nuclear Medicine and Biology. 22: 527-535. PMID 7550031 DOI: 10.1016/0969-8051(94)00118-4  0.341
1995 Kung MP, Essman WD, Frederick D, Meegalla S, Goodman M, Mu M, Lucki I, Kung HF. IPT: a novel iodinated ligand for the CNS dopamine transporter. Synapse (New York, N.Y.). 20: 316-24. PMID 7482291 DOI: 10.1002/Syn.890200405  0.355
1995 Meegalla S, Plössl K, Kung MP, Stevenson DA, Liable-Sands LM, Rheingold AL, Kung HF. First example of a 99mTc complex as a dopamine transporter imaging agent Journal of the American Chemical Society. 117: 11037-11038. DOI: 10.1021/Ja00149A039  0.341
1995 Chumpradit S, Kung M‐, Vessotskie J, Kung HF. Synthesis, resolution and radioiodination of S(−)trans‐5‐hydroxy‐2‐[N‐n‐propyl‐N‐(3′‐iodo‐2′‐propenyl)amino]tetralin‐S(−)trans‐5‐OH‐PIPAT: A new dopamine D2‐like receptor ligand Journal of Labelled Compounds and Radiopharmaceuticals. 36: 1051-1062. DOI: 10.1002/Jlcr.2580361105  0.338
1994 Goodman MM, Kung MP, Kabalka GW, Kung HF, Switzer R. Synthesis and characterization of radioiodinated N-(3-iodopropen-1-yl)-2 beta-carbomethoxy-3 beta-(4-chlorophenyl)tropanes: potential dopamine reuptake site imaging agents. Journal of Medicinal Chemistry. 37: 1535-42. PMID 8182712 DOI: 10.1021/Jm00036A020  0.324
1994 Garner SE, Kung MP, Foulon C, Chumpradit S, Kung HF. [125I](S)-trans-7-OH-PIPAT: a potential spect imaging agent for sigma binding sites. Life Sciences. 54: 593-603. PMID 8114613 DOI: 10.1016/0024-3205(94)00865-5  0.409
1994 Chumpradit S, Kung MP, Vessotskie J, Foulon C, Mu M, Kung HF. Iodinated 2-aminotetralins and 3-amino-1-benzopyrans: ligands for dopamine D2 and D3 receptors. Journal of Medicinal Chemistry. 37: 4245-50. PMID 7990123 DOI: 10.1021/Jm00050A021  0.331
1994 Shao L, Billings J, Pfeiffer N, Kung HF. Concentration recovery for SPECT CNS dopamine-receptor studies for monkeys. Medical Physics. 21: 675-81. PMID 7935203 DOI: 10.1118/1.597321  0.36
1994 Kung MP, Zhuang ZP, Frederick D, Kung HF. In vivo binding of [123I]4-(2'-methoxyphenyl)-1-[2'-(N-2"-pyridinyl)- p-iodobenzamido-]ethyl-piperazine, p-MPPI, to 5-HT1A receptors in rat brain. Synapse (New York, N.Y.). 18: 359-66. PMID 7886629 DOI: 10.1002/Syn.890180412  0.399
1994 Kung MP, Canney DJ, Frederick D, Zhuang Z, Billings JJ, Kung HF. Binding of 125I-iodovinyltetrabenazine to CNS vesicular monoamine transport sites. Synapse (New York, N.Y.). 18: 225-32. PMID 7855735 DOI: 10.1002/Syn.890180308  0.349
1994 Kung MP, Chumpradit S, Frederick D, Garner S, Burris KD, Molinoff PB, Kung HF. Characterization of binding sites for [125I]R(+)trans-7-OH-PIPAT in rat brain. Naunyn-Schmiedeberg's Archives of Pharmacology. 350: 611-7. PMID 7708118 DOI: 10.1007/Bf00169365  0.351
1993 Kung MP, Kung HF, Chumpradit S, Foulon C. In vitro binding of a novel dopamine D3 receptor ligand: [125I]trans-7-OH-PIPAT-A European Journal of Pharmacology. 235: 165-166. PMID 8519278 DOI: 10.1016/0014-2999(93)90839-A  0.337
1993 Guo YZ, Kung MP, Cheng H, Pfeiffer N, Mozley D, Kung HF. A simplified method for quantitation of iodine-123 iodobenzamide in human plasma: a technical note. European Journal of Nuclear Medicine. 20: 373-8. PMID 8519255 DOI: 10.1007/Bf00208994  0.3
1993 Billings JJ, Guo YZ, Kung MP, Kung HF. Localization of IBF as a D-2 dopamine receptor imaging agent in nonhuman primates European Journal of Nuclear Medicine. 20: 1146-1153. PMID 8299649 DOI: 10.1007/Bf00171012  0.405
1993 Chumpradit S, Kung MP, Kung HF. Synthesis and optical resolution of (R)- And (S)-trans-7-hydroxy-2-[N-propyl-N-(3′-iodo-2′-propenyl)amino] tetralin: A new D3 dopamine receptor ligand Journal of Medicinal Chemistry®. 36: 4308-4312. PMID 8277513 DOI: 10.1021/Jm00078A021  0.33
1993 Zhuang ZP, Kung MP, Kung HF. Synthesis of (R,S)-trans-8-hydroxy-2-[N-n-propyl-N-(3′-iodo-2′-propenyl)amino] tetralin (trans-8-OH-PIPAT): A new 5-HT1A receptor ligand Journal of Medicinal Chemistry. 36: 3161-3165. PMID 8230102 DOI: 10.1021/Jm00073A016  0.34
1993 Foulon C, Kung MP, Kung HF. Synthesis of (R,S)-2′-trans-7-hydroxy-2-[N-n-propyl-N-(3′-iodo-2′-propenyl) -amino]tetralin (trans-7-OH-PIPAT): A new D3 dopamine receptor ligand Journal of Medicinal Chemistry. 36: 1499-1500. PMID 8098771 DOI: 10.1021/Jm00062A025  0.303
1993 Chumpradit S, Kung MP, Billings J, Mach R, Kung HF. Fluorinated and iodinated dopamine agents: D2 imaging agents for PET and SPECT. Journal of Medicinal Chemistry. 36: 221-8. PMID 8093734 DOI: 10.1021/Jm00054A005  0.349
1993 Canney DJ, Guo Y‐, Kung M‐, Kung HF. Synthesis and preliminary evaluation of an iodovinyl‐tetrabenazine analog as a marker for the vesicular monoamine transporter Journal of Labelled Compounds and Radiopharmaceuticals. 33: 355-368. DOI: 10.1002/Jlcr.2580330413  0.355
1992 Ohmomo Y, Francesconi L, Kung MP, Kung HF. New conformationally restricted 99mTc N2S2 complexes as myocardial perfusion imaging agents Journal of Medicinal Chemistry. 35: 157-162. PMID 1732524 DOI: 10.1021/Jm00079A021  0.325
1992 Kung M, Chumpradit S, Billings J, Kung H. 4-Iodotomoxetine: A novel ligand for serotonin uptake sites Life Sciences. 51: 95-106. PMID 1614281 DOI: 10.1016/0024-3205(92)90002-7  0.324
1992 Billings JJ, Kung MP, Chumpradit S, Mozley D, Alavi A, Kung HF. Characterization of radioiodinated TISCH: a high-affinity and selective ligand for mapping CNS D1 dopamine receptor. Journal of Neurochemistry. 58: 227-36. PMID 1530770 DOI: 10.1111/J.1471-4159.1992.Tb09300.X  0.43
1992 Chumpradit S, Kung MP, Panyachotipun C, Prapansiri V, Foulon C, Brooks BP, Szabo SA, Tejani-Butt S, Frazer A, Kung HF. Iodinated tomoxetine derivatives as selective ligands for serotonin and norepinephrine uptake sites. Journal of Medicinal Chemistry. 35: 4492-7. PMID 1447750 DOI: 10.1021/Jm00101A029  0.319
1992 Broich K, Billings J, Shao L, Alavi A, Kung H. In vivo displacement of CNS D1 and D2 receptor binding measured by spect imaging International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology. 19: 138. DOI: 10.1016/0883-2897(92)90253-U  0.337
1991 Mach RH, Kung HF, Jungwiwattanaporn P, Guo YZ. Synthesis and biodistribution of a new class of 99mTc-labeled fatty acid analogs for myocardial imaging. International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology. 18: 215-26. PMID 2026498 DOI: 10.1016/0883-2897(91)90082-V  0.301
1991 Kung HF. Overview of radiopharmaceuticals for diagnosis of central nervous disorders Critical Reviews in Clinical Laboratory Sciences. 28: 269-286. PMID 1930679 DOI: 10.3109/10408369109106866  0.391
1991 John CS, Kung MP, Billings J, Kung HF. Preparation, radiolabeling and biodistribution of a new class of bisaminothiol (BAT) ligands as possible imaging agents. International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology. 18: 551-6. PMID 1917525 DOI: 10.1016/0883-2897(91)90117-4  0.41
1991 Chumpradit S, Kung MP, Billings JJ, Kung HF. Synthesis and resolution of (±)-7-chloro-8-hydroxy-1-(3′-iodophenyl)-3-methyl-2,3,4,5- tetrahydro-1H-3-benzazepine (TISCH): A high affinity and selective iodinated ligand for CNS D1 dopamine receptor Journal of Medicinal Chemistry. 34: 877-883. PMID 1825848 DOI: 10.1021/Jm00107A002  0.373
1991 Chumpradit S, Kung MP, Billings JJ, Kung HF. Synthesis and resolution of (.+-.)-7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine (TISCH): a high affinity and selective iodinated ligand for CNS D1 dopamine receptor [Erratum to document cited in CA114(13):122017d] Journal of Medicinal Chemistry. 34: 3405-3405. DOI: 10.1021/Jm00116A013  0.308
1990 Shih WJ, Coupal JJ, Magoun S, Pulmano C, Kung HF, Ryo YY. I-123 HIPDM planar brain images demonstrating crossed cerebellar diaschisis. Clinical Nuclear Medicine. 15: 34-7. PMID 2306896 DOI: 10.1097/00003072-199001000-00011  0.329
1990 Kung HF, Ohmomo Y, Kung MP. Current and future radiopharmaceuticals for brain imaging with single photon emission computed tomography Seminars in Nuclear Medicine. 20: 290-302. PMID 2237449 DOI: 10.1016/S0001-2998(05)80235-1  0.381
1990 Kung HF. New technetium 99m-labeled brain perfusion imaging agents Seminars in Nuclear Medicine. 20: 150-158. PMID 2184522 DOI: 10.1016/S0001-2998(05)80167-9  0.377
1990 Kung HF. Radiopharmaceuticals for CNS receptor imaging with SPECT Nuclear Medicine and Biology. 17: 85-92. PMID 2155190 DOI: 10.1016/0883-2897(90)90012-P  0.331
1990 Filtz TM, Chumpradit S, Kung HF, Molinoff PB. Synthesis and applications of an aldehyde-containing analogue of SCH-23390. Bioconjugate Chemistry. 1: 394-9. PMID 2151561 DOI: 10.1021/Bc00006A005  0.347
1990 Murphy RA, Kung HF, Kung MP, Billings J. Synthesis and characterization of iodobenzamide analogues: potential D-2 dopamine receptor imaging agents. Journal of Medicinal Chemistry. 33: 171-8. PMID 2136916 DOI: 10.1021/Jm00163A029  0.398
1990 Efange SM, Kung HF, Mash DC, Jabir M, Billings J, Pablo J, Dutta A, Freshler A. Pargyline-sensitive selective accumulation of a radiolabeled MPTP analog in the primate cerebral cortex and basal ganglia. Synapse (New York, N.Y.). 5: 207-12. PMID 2111588 DOI: 10.1002/Syn.890050306  0.321
1989 Chumpradit S, Kung HF, Billings J, Guo YZ, Wu Y, Shih J. Preparation and biodistribution of 1-[2-(3-[125I]iodo-4-aminophenyl)ethyl]-4-[3-(trifluoromethyl) phenyl]piperazine and 1-[2-(3-[125I]iodo-4-azidophenyl)ethyl]-4-[3-(trifluoromethyl)phenyl] piperazine. Journal of Medicinal Chemistry. 32: 543-7. PMID 2918500 DOI: 10.1021/Jm00123A006  0.4
1989 Billings J, Kung MP, Chumpradit S, Pan S, Kung HF. [125I](+/-)FISCH: a new CNS D-1 dopamine receptor imaging ligand. Life Sciences. 45: 711-8. PMID 2779358 DOI: 10.1016/0024-3205(89)90090-8  0.403
1989 Chumpradit S, Kung HF, Billings J, Kung MP, Pan S. (+/-)-7-chloro-8-hydroxy-1-(4'-[125I]iodophenyl)-3-methyl-2,3,4,5- tetrahydro-1H-3-benzazepine: a potential CNS D-1 dopamine receptor imaging agent. Journal of Medicinal Chemistry. 32: 1431-5. PMID 2525621 DOI: 10.1021/Jm00127A005  0.417
1989 Velchik MG, Kung HF, Alavi A, Kung MP, Chang W, Noto R, Pan S, Billings J, Sorgentoni K, Rauch A, Reilley J. l-123-IBZM: A CNS D2 RECEPTOR AGENT BIODISTRIBUTION & IMAGING IN HUMANS Clinical Nuclear Medicine. 14: 232. DOI: 10.1097/00003072-198903000-00030  0.327
1989 Kung M, Kung HF. Peracetic acid as a superior oxidant for preparation of [123I]IBZM: A potential dopamine D-2 receptor imaging agent Journal of Labelled Compounds and Radiopharmaceuticals. 27: 691-700. DOI: 10.1002/Jlcr.2580270612  0.321
1988 Brücke T, Tsai YF, McLellan C, Singhanyom W, Kung HF, Cohen RM, Chiueh CC. In vitro binding properties and autoradiographic imaging of 3-iodobenzamide ([125I]-IBZM): a potential imaging ligand for D-2 dopamine receptors in SPECT. Life Sciences. 42: 2097-104. PMID 3260318 DOI: 10.1016/0024-3205(88)90123-3  0.412
1988 Efange SM, Kung HF, Billings JJ, Blau M. Synthesis and biodistribution of 99mTc-labeled piperidinyl bis(aminoethanethiol) complexes: potential brain perfusion imaging agents for single photon emission computed tomography. Journal of Medicinal Chemistry. 31: 1043-7. PMID 3258924 DOI: 10.1021/Jm00400A028  0.38
1988 Singhaniyom W, Tsai YF, Brücke T, McLellan CA, Cohen RM, Kung HF, Chiueh CC. Blockade of in vivo binding of 125I-labeled 3-iodobenzamide (IBZM) to dopamine receptors by D2 antagonist and agonist. Brain Research. 453: 393-396. PMID 2969766 DOI: 10.1016/0006-8993(88)90186-2  0.359
1988 Kung HF, Kasliwal R, Pan S, Kung MP, Mach RH, Guo YZ. Dopamine D-2 receptor imaging radiopharmaceuticals: Synthesis, radiolabeling, and in vitro binding of (R)-(+)- and (S)-(-)-3-iodo-2-hydroxy-6-methoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]benzamide Journal of Medicinal Chemistry. 31: 1039-1043. PMID 2966245 DOI: 10.1021/Jm00400A027  0.387
1985 Kung HF, Yu CC, Billings J, Molnar M, Blau M. Synthesis of new bis(aminoethanethiol) (BAT) derivatives: possible ligands for 99mTc brain imaging agents. Journal of Medicinal Chemistry. 28: 1280-4. PMID 2993617 DOI: 10.1002/Chin.198552171  0.403
1983 Tramposch KM, Kung HF, Blau M. Radioiodine-labeled N,N-dimethyl-N'-(2-hydroxy-3-alkyl-5-iodobenzyl)-1,3-propanediamines for brain perfusion imaging. Journal of Medicinal Chemistry. 26: 121-5. PMID 6402595 DOI: 10.1002/Chin.198328134  0.306
1983 Blau M, Kung H, Wicks R, Steinbach J. Radiation dose to humans from 75Se MOSE ph shift brain imaging agent International Journal of Nuclear Medicine and Biology. 10: 55-56. DOI: 10.1016/0047-0740(83)90066-9  0.305
1982 Tramposch KM, Kung HF, Blau M. Synthesis and tissue distribution study of iodine-labeled benzyl- and xylylamines. Journal of Medicinal Chemistry. 25: 870-3. PMID 7108905 DOI: 10.1021/Jm00349A022  0.369
1980 Kung H, Blau M. Synthesis of selenium-75 labeled tertiary diamines: New brain imaging agents Journal of Medicinal Chemistry. 23: 1127-1130. PMID 7420357 DOI: 10.1002/Chin.198110304  0.307
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