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Jacques H. van Boom, Ph.D. - Publications

Affiliations: 
Chemistry Leiden University, Leiden, Netherlands 
Area:
synthetic organic chemistry
Website:
http://www.dwc.knaw.nl/biografie/pmknaw/?pagetype=authorDetail&aId=PE00003746
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Year Citation  Score
2005 Voerman G, Cavalli S, van der Marel GA, Pfleiderer W, van Boom JH, Filippov DV. 1,3-Dimethyllumazine derivatives from Limnatis nilotica. Journal of Natural Products. 68: 938-41. PMID 15974624 DOI: 10.1021/np049617a  0.421
2005 Codée JD, Stubba B, Schiattarella M, Overkleeft HS, van Boeckel CA, van Boom JH, van der Marel GA. A modular strategy toward the synthesis of heparin-like oligosaccharides using monomeric building blocks in a sequential glycosylation strategy. Journal of the American Chemical Society. 127: 3767-73. PMID 15771511 DOI: 10.1021/ja045613g  0.641
2005 Timmer MSM, Chumillas MV, Donker-Koopman WE, Aerts JMFG, Van Der Marel GA, Overkleeft HS, Van Boom JH. Selective cross-metathesis of C-allyl-glycosides Journal of Carbohydrate Chemistry. 24: 335-351. DOI: 10.1080/07328300500174887  0.371
2004 Welters MJ, Filippov DV, van den Eeden SJ, Franken KL, Nouta J, Valentijn AR, van der Marel GA, Overkleeft HS, Lipford G, Offringa R, Melief CJ, van Boom JH, van der Burg SH, Drijfhout JW. Chemically synthesized protein as tumour-specific vaccine: immunogenicity and efficacy of synthetic HPV16 E7 in the TC-1 mouse tumour model. Vaccine. 23: 305-11. PMID 15530672 DOI: 10.1016/J.Vaccine.2004.06.008  0.336
2004 Grotenbreg GM, Kronemeijer M, Timmer MS, El Oualid F, van Well RM, Verdoes M, Spalburg E, van Hooft PA, de Neeling AJ, Noort D, van Boom JH, van der Marel GA, Overkleeft HS, Overhand M. A practical synthesis of gramicidin s and sugar amino Acid containing analogues. The Journal of Organic Chemistry. 69: 7851-9. PMID 15527261 DOI: 10.1021/Jo0487449  0.417
2004 van den Berg RJ, Korevaar CG, Overkleeft HS, van der Marel GA, van Boom JH. Effective, high-yielding, and stereospecific total synthesis of D-erythro-(2R,3S)-sphingosine from D-ribo-(2S,3S,4R)-phytosphingosine. The Journal of Organic Chemistry. 69: 5699-704. PMID 15307742 DOI: 10.1021/jo049277y  0.41
2004 El Oualid F, Burm BE, Leroy IM, Cohen LH, van Boom JH, van den Elst H, Overkleeft HS, van der Marel GA, Overhand M. Design, synthesis, and evaluation of sugar amino acid based inhibitors of protein prenyl transferases PFT and PGGT-1. Journal of Medicinal Chemistry. 47: 3920-3. PMID 15267228 DOI: 10.1021/Jm049927Q  0.382
2004 Tromp RA, van Boom SS, Marco Timmers C, van Zutphen S, van der Marel GA, Overkleeft HS, van Boom JH, Reedijk J. The beta-glucuronyl-based prodrug strategy allows for its application on beta-glucuronyl-platinum conjugates. Bioorganic & Medicinal Chemistry Letters. 14: 4273-6. PMID 15261285 DOI: 10.1016/J.Bmcl.2004.06.015  0.349
2004 van Roon AM, Pannu NS, de Vrind JP, van der Marel GA, van Boom JH, Hokke CH, Deelder AM, Abrahams JP. Structure of an anti-Lewis X Fab fragment in complex with its Lewis X antigen. Structure (London, England : 1993). 12: 1227-36. PMID 15242599 DOI: 10.1016/j.str.2004.05.008  0.401
2004 Verhelst SH, Michiels PJ, van der Marel GA, van Boeckel CA, van Boom JH. Surface plasmon resonance evaluation of various aminoglycoside-RNA hairpin interactions reveals low degree of selectivity. Chembiochem : a European Journal of Chemical Biology. 5: 937-42. PMID 15239050 DOI: 10.1002/cbic.200300819  0.394
2004 van den Bos LJ, Codée JD, van der Toorn JC, Boltje TJ, van Boom JH, Overkleeft HS, van der Marel GA. Thioglycuronides: synthesis and application in the assembly of acidic oligosaccharides. Organic Letters. 6: 2165-8. PMID 15200311 DOI: 10.1021/ol049380+  0.63
2004 Petersen L, de Koning MC, van Kuik-Romeijn P, Weterings J, Pol CJ, Platenburg G, Overhand M, van der Marel GA, van Boom JH. Synthesis and in vitro evaluation of PNA-peptide-DETA conjugates as potential cell penetrating artificial ribonucleases. Bioconjugate Chemistry. 15: 576-82. PMID 15149186 DOI: 10.1021/Bc034219P  0.415
2004 van Hooft PA, El Oualid F, Overkleeft HS, van der Marel GA, van Boom JH, Leeuwenburgh MA. Synthesis and elaboration of functionalised carbohydrate-derived spiroketals. Organic & Biomolecular Chemistry. 2: 1395-403. PMID 15105932 DOI: 10.1039/b401699h  0.41
2004 Gómez-Pinto I, Cubero E, Kalko SG, Monaco V, van der Marel G, van Boom JH, Orozco M, González C. Effect of bulky lesions on DNA: solution structure of a DNA duplex containing a cholesterol adduct. The Journal of Biological Chemistry. 279: 24552-60. PMID 15047709 DOI: 10.1074/jbc.M311751200  0.37
2003 van den Bos LJ, Codée JD, van Boom JH, Overkleeft HS, van der Marel GA. A novel strategy towards the synthesis of orthogonally functionalised 4-aminoglycosides. Organic & Biomolecular Chemistry. 1: 4160-5. PMID 14685319 DOI: 10.1039/b309823k  0.644
2003 Verhelst SH, Paez Martinez B, Timmer MS, Lodder G, van der Marel GA, Overkleeft HS, van Boom JH. A short route toward chiral, polyhydroxylated indolizidines and quinolizidines. The Journal of Organic Chemistry. 68: 9598-603. PMID 14656083 DOI: 10.1021/jo0350662  0.382
2003 Timmer MS, Verdoes M, Sliedregt LA, van der Marel GA, van Boom JH, Overkleeft HS. The use of a mannitol-derived fused oxacycle as a combinatorial scaffold. The Journal of Organic Chemistry. 68: 9406-11. PMID 14629165 DOI: 10.1021/jo0349429  0.442
2003 van Rossenberg SM, Sliedregt-Bol KM, Prince P, van Berkel TJ, van Boom JH, van der Marel GA, Biessen EA. A targeted peptide nucleic acid to down-regulate mouse microsomal triglyceride transfer protein expression in hepatocytes. Bioconjugate Chemistry. 14: 1077-82. PMID 14624620 DOI: 10.1021/bc0340417  0.37
2003 Robillard MS, Bacac M, van den Elst H, Flamigni A, van der Marel GA, van Boom JH, Reedijk J. Automated parallel solid-phase synthesis and anticancer screening of a library of peptide-tethered platinum(II) complexes. Journal of Combinatorial Chemistry. 5: 821-5. PMID 14606811 DOI: 10.1021/Cc030011Z  0.388
2003 van Well RM, Marinelli L, Altona C, Erkelens K, Siegal G, van Raaij M, Llamas-Saiz AL, Kessler H, Novellino E, Lavecchia A, van Boom JH, Overhand M. Conformational analysis of furanoid epsilon-sugar amino acid containing cyclic peptides by NMR spectroscopy, molecular dynamics simulation, and X-ray crystallography: evidence for a novel turn structure. Journal of the American Chemical Society. 125: 10822-9. PMID 12952461 DOI: 10.1021/JA035461+  0.575
2003 Aguilera B, Ghauharali-van der Vlugt K, Helmond MT, Out JM, Donker-Koopman WE, Groener JE, Boot RG, Renkema GH, van der Marel GA, van Boom JH, Overkleeft HS, Aerts JM. Transglycosidase activity of chitotriosidase: improved enzymatic assay for the human macrophage chitinase. The Journal of Biological Chemistry. 278: 40911-6. PMID 12890686 DOI: 10.1074/Jbc.M301804200  0.348
2003 Robillard MS, Davies NP, van der Marel GA, van Boom JH, Reedijk J, Murray V. The interaction of peptide-tethered platinum(II) complexes with DNA. Journal of Inorganic Biochemistry. 96: 331-8. PMID 12888268 DOI: 10.1016/S0162-0134(03)00180-6  0.451
2003 van Rossenberg SM, Sliedregt-Bol KM, Koning G, van den Elst H, van Berkel TJ, van Boom JH, van der Marel GA, Biessen EA. Improvement of hepatocyte-specific gene expression by a targeted colchicine prodrug. Chembiochem : a European Journal of Chemical Biology. 4: 633-9. PMID 12851933 DOI: 10.1002/cbic.200300582  0.382
2003 Grotenbreg GM, Spalburg E, de Neeling AJ, van der Marel GA, Overkleeft HS, van Boom JH, Overhand M. Synthesis and biological evaluation of novel turn-modified gramicidin S analogues. Bioorganic & Medicinal Chemistry. 11: 2835-41. PMID 12788356 DOI: 10.1016/S0968-0896(03)00219-0  0.402
2003 Codée JD, van den Bos LJ, Litjens RE, Overkleeft HS, van Boom JH, van der Marel GA. Sequential one-pot glycosylations using 1-hydroxyl and 1-thiodonors. Organic Letters. 5: 1947-50. PMID 12762693 DOI: 10.1021/ol034528v  0.635
2003 de Visser PC, Kriek NM, van Hooft PA, Van Schepdael A, Filippov DV, van der Marel GA, Overkleeft HS, van Boom JH, Noort D. Solid-phase synthesis of polymyxin B1 and analogues via a safety-catch approach. The Journal of Peptide Research : Official Journal of the American Peptide Society. 61: 298-306. PMID 12753377 DOI: 10.1034/j.1399-3011.2003.00061.x  0.42
2003 Codée JD, Litjens RE, den Heeten R, Overkleeft HS, van Boom JH, van der Marel GA. Ph2SO/Tf2O: a powerful promotor system in chemoselective glycosylations using thioglycosides. Organic Letters. 5: 1519-22. PMID 12713313 DOI: 10.1021/ol034312t  0.628
2003 Heetebrij RJ, de Kort M, Meeuwenoord NJ, den Dulk H, van der Marel GA, van Boom JH, Reedijk J. A versatile approach towards regioselective platinated DNA sequences. Chemistry (Weinheim An Der Bergstrasse, Germany). 9: 1823-7. PMID 12698440 DOI: 10.1002/Chem.200390209  0.44
2003 van Well RM, Overkleeft HS, van der Marel GA, Bruss D, Thibault G, de Groot PG, van Boom JH, Overhand M. Solid-phase synthesis of cyclic RGD-furanoid sugar amino acid peptides as integrin inhibitors. Bioorganic & Medicinal Chemistry Letters. 13: 331-4. PMID 12565923 DOI: 10.1016/S0960-894X(02)01022-3  0.37
2003 Leeuwenburgh MA, Van Der Marel GA, Overkleeft HS, Van Boom JH. From α-1,2-Anhydrosugars to C-Glycosides: The Influence of Lewis Acids and Nucleophiles on the Stereochemistry Journal of Carbohydrate Chemistry. 22: 549-564. DOI: 10.1081/CAR-120026458  0.373
2002 Schmidt KS, Boudvillain M, Schwartz A, van der Marel GA, van Boom JH, Reedijk J, Lippert B. Monofunctionally trans-diammine platinum(II)-modified peptide nucleic acid oligomers: a new generation of potential antisense drugs. Chemistry (Weinheim An Der Bergstrasse, Germany). 8: 5566-70. PMID 12458496 DOI: 10.1002/1521-3765(20021216)8:24<5566::Aid-Chem5566>3.0.Co;2-#  0.442
2002 Van Rossenberg SM, Sliedregt-Bol KM, Meeuwenoord NJ, Van Berkel TJ, Van Boom JH, Van Der Marel GA, Biessen EA. Targeted lysosome disruptive elements for improvement of parenchymal liver cell-specific gene delivery. The Journal of Biological Chemistry. 277: 45803-10. PMID 12237290 DOI: 10.1074/jbc.M203510200  0.358
2002 Rapozzi V, Burm BE, Cogoi S, van der Marel GA, van Boom JH, Quadrifoglio F, Xodo LE. Antiproliferative effect in chronic myeloid leukaemia cells by antisense peptide nucleic acids. Nucleic Acids Research. 30: 3712-21. PMID 12202756  0.409
2002 Verhoeven EE, van Kesteren M, Turner JJ, van der Marel GA, van Boom JH, Moolenaar GF, Goosen N. The C-terminal region of Escherichia coli UvrC contributes to the flexibility of the UvrABC nucleotide excision repair system. Nucleic Acids Research. 30: 2492-500. PMID 12034838 DOI: 10.1093/Nar/30.11.2492  0.497
2002 Sabatini R, Meeuwenoord N, van Boom JH, Borst P. Site-specific interactions of JBP with base and sugar moieties in duplex J-DNA. Evidence for both major and minor groove contacts. The Journal of Biological Chemistry. 277: 28150-6. PMID 12029082 DOI: 10.1074/Jbc.M201487200  0.321
2002 Ouwerkerk N, Steenweg M, de Ruijter M, Brouwer J, van Boom JH, Lugtenburg J, Raap J. One-pot two-step enzymatic coupling of pyrimidine bases to 2-deoxy-D-ribose-5-phosphate. A new strategy in the synthesis of stable isotope labeled deoxynucleosides. The Journal of Organic Chemistry. 67: 1480-9. PMID 11871876 DOI: 10.1021/Jo0107249  0.753
2002 Sabatini R, Meeuwenoord N, van Boom JH, Borst P. Recognition of base J in duplex DNA by J-binding protein. The Journal of Biological Chemistry. 277: 958-66. PMID 11700315 DOI: 10.1074/Jbc.M109000200  0.314
2001 Soliva R, Monaco V, Gómez-Pinto I, Meeuwenoord NJ, Van Der Marel GA, Van Boom JH, González C, Orozco M. Solution structure of a DNA duplex with a chiral alkyl phosphonate moiety Nucleic Acids Research. 29: 2973-2985. PMID 11452022 DOI: 10.1093/Nar/29.14.2973  0.371
2001 Aguilera B, Wolf LB, Nieczypor P, Rutjes FP, Overkleeft HS, van Hest JC, Schoemaker HE, Wang B, Mol JC, Fürstner A, Overhand M, van der Marel GA, van Boom JH. Synthesis of diaminosuberic acid derivatives via ring-closing alkyne metathesis. The Journal of Organic Chemistry. 66: 3584-9. PMID 11348148 DOI: 10.1021/Jo001734X  0.389
2001 Sliedregt LA, van Rossenberg SM, Autar R, Valentijn AR, van der Marel GA, van Boom JH, Piperi C, van der Merwe PA, Kuiper J, van Berkel TJ, Biessen EA. Design and synthesis of a multivalent homing device for targeting to murine CD22. Bioorganic & Medicinal Chemistry. 9: 85-97. PMID 11197350 DOI: 10.1016/S0968-0896(00)00224-8  0.363
2001 Cogoi S, Suraci C, Del Terra E, Diviacco S, van der Marel G, van Boom J, Quadrifoglio F, Xodo L. Downregulation of c-Ki-ras promoter activity by triplex-forming oligonucleotides endogenously generated in human 293 cells. Antisense & Nucleic Acid Drug Development. 10: 283-95. PMID 10984122 DOI: 10.1089/108729000421466  0.405
2001 De Kort M, De Visser PC, Kurzeck J, Meeuwenoord NJ, Van Der Marel GA, Rüger W, Van Boom JH. Chemical and enzymatic synthesis of DNA fragments containing 5-(β-D-glucopyranosyloxymethyl)-2′-deoxycytidine - A modified nucleoside in T4 phage DNA European Journal of Organic Chemistry. 2075-2082.  0.322
2000 Verheijen JC, Chen L, Bayly SF, Torrence PF, van der Marel GA, van Boom JH. Synthesis and RNAse L binding and activation of a 2-5A-(5')-DNA-(3')-PNA chimera, a novel potential antisense molecule. Nucleosides, Nucleotides & Nucleic Acids. 19: 1821-30. PMID 11200276 DOI: 10.1080/15257770008045463  0.457
2000 Verheijen JC, van Der Marel GA, van Boom JH, Metzler-Nolte N. Transition metal derivatives of peptide nucleic acid (PNA) oligomers-synthesis, characterization, and DNA binding. Bioconjugate Chemistry. 11: 741-3. PMID 11087319 DOI: 10.1021/bc0000740  0.49
2000 de Kort M, Regenbogen AD, Valentijn AR, Challiss RA, Iwata Y, Miyamoto S, van der Marel GA, van Boom JH. Spirophostins: conformationally restricted analogues of adenophostin A. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 2696-704. PMID 10985718 DOI: 10.1002/1521-3765(20000804)6:15<2696::AID-CHEM2696>3.0.CO;2-Y  0.41
2000 de Kort M, Correa V, Valentijn AR, van der Marel GA, Potter BV, Taylor CW, van Boom JH. Synthesis of potent agonists of the D-myo-inositol 1,4, 5-trisphosphate receptor based on clustered disaccharide polyphosphate analogues of adenophostin A. Journal of Medicinal Chemistry. 43: 3295-303. PMID 10966748 DOI: 10.1021/Jm000957C  0.415
2000 Verheijen JC, van Roon AM, Meeuwenoord NJ, Stuivenberg HR, Bayly SF, Chen L, van der Marel GA, Torrence PF, van Boom JH. Incorporation of a 4-hydroxy-N-acetylprolinol nucleotide analogue improves the 3'-exonuclease stability of 2'-5'-oligoadenylate-antisense conjugates. Bioorganic & Medicinal Chemistry Letters. 10: 801-4. PMID 10782690 DOI: 10.1016/S0960-894X(00)00100-1  0.481
2000 Moolenaar GF, Herron MF, Monaco V, van der Marel GA, van Boom JH, Visse R, Goosen N. The role of ATP binding and hydrolysis by UvrB during nucleotide excision repair. The Journal of Biological Chemistry. 275: 8044-50. PMID 10713125 DOI: 10.1074/Jbc.275.11.8044  0.488
2000 Moolenaar GF, Monaco V, van der Marel GA, van Boom JH, Visse R, Goosen N. The effect of the DNA flanking the lesion on formation of the UvrB-DNA preincision complex. Mechanism for the UvrA-mediated loading of UvrB onto a DNA damaged site. The Journal of Biological Chemistry. 275: 8038-43. PMID 10713124 DOI: 10.1074/Jbc.275.11.8038  0.477
2000 Ouwerkerk N, Van Boom JH, Lugtenburg J, Raap J. Chemo-enzymatic synthesis of thymidine 13C-labelled in the 2'- deoxyribose moiety European Journal of Organic Chemistry. 861-866. DOI: 10.1002/(Sici)1099-0690(200003)2000:5<861::Aid-Ejoc861>3.0.Co;2-E  0.744
1999 Cross M, Kieft R, Sabatini R, Wilm M, de Kort M, van der Marel GA, van Boom JH, van Leeuwen F, Borst P. The modified base J is the target for a novel DNA-binding protein in kinetoplastid protozoans. The Embo Journal. 18: 6573-81. PMID 10562569 DOI: 10.1093/Emboj/18.22.6573  0.484
1999 Buijsman RC, Basten JE, Dreef-Tromp CM, van der Marel GA, van Boeckel CA, van Boom JH. Synthesis of heparin-like antithrombotics having perphosphorylated thrombin binding domains. Bioorganic & Medicinal Chemistry. 7: 1881-90. PMID 10530936 DOI: 10.1016/S0968-0896(99)00139-X  0.381
1999 van Dongen MJ, Doreleijers JF, van der Marel GA, van Boom JH, Hilbers CW, Wijmenga SS. Structure and mechanism of formation of the H-y5 isomer of an intramolecular DNA triple helix. Nature Structural Biology. 6: 854-9. PMID 10467098 DOI: 10.1038/12313  0.575
1999 Buijsman RC, Basten JE, van Dinther TG, van der Marel GA, van Boeckel CA, van Boom JH. Design and synthesis of a novel synthetic NAPAP-penta-saccharide conjugate displaying a dual antithrombotic action. Bioorganic & Medicinal Chemistry Letters. 9: 2013-8. PMID 10450972 DOI: 10.1016/S0960-894X(99)00320-0  0.417
1999 Verheijen JC, van der Marel GA, van Boom JH, Bayly SF, Player MR, Torrence PF. 2,5-oligoadenylate-peptide nucleic acids (2-5A-PNAs) activate RNase L. Bioorganic & Medicinal Chemistry. 7: 449-55. PMID 10220031 DOI: 10.1016/S0968-0896(98)00258-2  0.393
1999 Beecroft MD, Marchant JS, Riley AM, Van Straten NC, Van der Marel GA, Van Boom JH, Potter BV, Taylor CW. Acyclophostin: a ribose-modified analog of adenophostin A with high affinity for inositol 1,4,5-trisphosphate receptors and pH-dependent efficacy. Molecular Pharmacology. 55: 109-17. PMID 9882704 DOI: 10.1124/Mol.55.1.109  0.372
1998 van der Laan AC, Havenaar P, Oosting RS, Kuyl-Yeheskiely E, Uhlmann E, van Boom JH. Optimization of the binding properties of PNA-(5')-DNA chimerae. Bioorganic & Medicinal Chemistry Letters. 8: 663-8. PMID 9871579 DOI: 10.1016/S0960-894X(98)00088-2  0.31
1998 Gao YG, Robinson H, Guan Y, Liaw YC, van Boom JH, van der Marel GA, Wang AH. Molecular structure of two crystal forms of cyclic triadenylic acid at 1A resolution. Journal of Biomolecular Structure & Dynamics. 16: 69-76. PMID 9745896 DOI: 10.1080/07391102.1998.10508228  0.502
1998 van Leeuwen F, de Kort M, van der Marel GA, van Boom JH, Borst P. The modified DNA base beta-D-glucosylhydroxymethyluracil confers resistance to micrococcal nuclease and is incompletely recovered by 32P-postlabeling. Analytical Biochemistry. 258: 223-9. PMID 9570833 DOI: 10.1006/Abio.1998.2587  0.308
1998 Ippel HH, Van Elst HD, Van Der Marel GA, Van Boom JH, Altona C. Structural similarities and differences between H1- and H2-family DNA minihairpin loops: NMR studies of octameric minihairpins Biopolymers. 46: 375-393. DOI: 10.1002/(SICI)1097-0282(199811)46:6<375::AID-BIP3>3.0.CO;2-6  0.572
1997 van Dongen MJ, Mooren MM, Willems EF, van der Marel GA, van Boom JH, Wijmenga SS, Hilbers CW. Structural features of the DNA hairpin d(ATCCTA-GTTA-TAGGAT): formation of a G-A base pair in the loop. Nucleic Acids Research. 25: 1537-47. PMID 9092659 DOI: 10.1093/nar/25.8.1537  0.682
1997 Slijper M, Boelens R, Davis AL, Konings RN, van der Marel GA, van Boom JH, Kaptein R. Backbone and side chain dynamics of lac repressor headpiece (1-56) and its complex with DNA. Biochemistry. 36: 249-54. PMID 8993340 DOI: 10.1021/Bi961670D  0.529
1996 van Delft FL, de Kort M, van Der Marel GA, van Boom JH. Use of a Novel alpha-Hydroxyethylating Reagent in the Stereoselective Synthesis of Lincosamine. The Journal of Organic Chemistry. 61: 1883-1885. PMID 11667071  0.349
1996 Zegelaar-Jaarsveld K, Smits SA, van der Marel GA, van Boom JH. Synthesis of a pentasaccharide corresponding to the repeating unit of the exopolysaccharide from Cryptococcus neoformans serovar D. Bioorganic & Medicinal Chemistry. 4: 1819-32. PMID 9007267 DOI: 10.1016/S0968-0896(96)00164-2  0.439
1996 Ohishi H, Terasoma N, Nakanishi I, van der Marel G, van Boom JH, Rich A, Wang AH, Hakoshima T, Tomita K. Interaction between left-handed Z-DNA and polyamine - 3. The crystal structure of the d(CG)3 and thermospermine complex. Febs Letters. 398: 291-6. PMID 8977125 DOI: 10.1016/S0014-5793(96)01225-2  0.616
1996 van Dongen MJ, Wijmenga SS, van der Marel GA, van Boom JH, Hilbers CW. The transition from a neutral-pH double helix to a low-pH triple helix induces a conformational switch in the CCCG tetraloop closing a Watson-Crick stem. Journal of Molecular Biology. 263: 715-29. PMID 8947571 DOI: 10.1006/jmbi.1996.0611  0.69
1996 Pikkemaat JA, Overmars FJ, Dreef-Tromp CM, van den Elst H, van Boom JH, Altona C. Conformational aspects of an uncharged phosphate analogon built in at the branch-point of a DNA four-way junction. Journal of Molecular Biology. 262: 349-57. PMID 8845000 DOI: 10.1006/jmbi.1996.0518  0.586
1996 Ohishi H, Nakanishi I, Inubushi K, van der Marel G, van Boom JH, Rich A, Wang AH, Hakoshima T, Tomita K. Interaction between the left-handed Z-DNA and polyamine-2. The crystal structure of the d(CG)3 and spermidine complex. Febs Letters. 391: 153-6. PMID 8706905 DOI: 10.1016/0014-5793(96)00723-5  0.604
1996 van Leeuwen F, Wijsman ER, Kuyl-Yeheskiely E, van der Marel GA, van Boom JH, Borst P. The telomeric GGGTTA repeats of Trypanosoma brucei contain the hypermodified base J in both strands. Nucleic Acids Research. 24: 2476-82. PMID 8692684 DOI: 10.1093/Nar/24.13.2476  0.306
1996 van Dongen MJ, Heus HA, Wymenga SS, van der Marel GA, van Boom JH, Hilbers CW. Unambiguous structure characterization of a DNA-RNA triple helix by 15N- and 13C-filtered NOESY spectroscopy. Biochemistry. 35: 1733-9. PMID 8639652 DOI: 10.1021/bi952002f  0.676
1996 Overmars FJ, Pikkemaat JA, van den Elst H, van Boom JH, Altona C. NMR studies of DNA three-way junctions containing two unpaired thymidine bases: the influence of the sequence at the junction on the stability of the stacking conformers. Journal of Molecular Biology. 255: 702-13. PMID 8636972 DOI: 10.1006/jmbi.1996.0057  0.636
1996 Ippel JH, Wijmenga SS, De Jong R, Heus HA, Hilbers CW, De Vroom E, Van Der Marel GA, Van Boom JH. Heteronuclear scalar couplings in the bases and sugar rings of nucleic acids: Their determination and application in assignment and conformational analysis Magnetic Resonance in Chemistry. 34: S156-S176. DOI: 10.1002/(Sici)1097-458X(199612)34:133.0.Co;2-U  0.536
1995 Gao YG, Robinson H, van Boom JH, Wang AH. Influence of counter-ions on the crystal structures of DNA decamers: binding of [Co(NH3)6]3+ and Ba2+ to A-DNA. Biophysical Journal. 69: 559-68. PMID 8527670 DOI: 10.1016/S0006-3495(95)79929-5  0.374
1995 Yang D, van Boom SS, Reedijk J, van Boom JH, Farrell N, Wang AH. A novel DNA structure induced by the anticancer bisplatinum compound crosslinked to a GpC site in DNA. Nature Structural Biology. 2: 577-8. PMID 7664126 DOI: 10.1038/Nsb0795-577  0.341
1995 Yang D, van Boom SS, Reedijk J, van Boom JH, Wang AH. Structure and isomerization of an intrastrand cisplatin-cross-linked octamer DNA duplex by NMR analysis. Biochemistry. 34: 12912-20. PMID 7548048 DOI: 10.1021/Bi00039A054  0.311
1995 Bloemberg GV, Lagas RM, van Leeuwen S, Van der Marel GA, Van Boom JH, Lugtenberg BJ, Spaink HP. Substrate specificity and kinetic studies of nodulation protein NodL of Rhizobium leguminosarum. Biochemistry. 34: 12712-20. PMID 7548024 DOI: 10.1021/Bi00039A030  0.408
1994 Mooren MM, Wijmenga SS, van der Marel GA, van Boom JH, Hilbers CW. The solution structure of the circular trinucleotide cr(GpGpGp) determined by NMR and molecular mechanics calculation. Nucleic Acids Research. 22: 2658-66. PMID 8041628  0.581
1994 Pikkemaat JA, van den Elst H, van Boom JH, Altona C. NMR studies and conformational analysis of a DNA four-way junction formed in a linear synthetic oligonucleotide. Biochemistry. 33: 14896-907. PMID 7993916  0.625
1994 Vega MC, García Sáez I, Aymamí J, Eritja R, Van der Marel GA, Van Boom JH, Rich A, Coll M. Three-dimensional crystal structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor-groove-binding drug Hoechst 33258. European Journal of Biochemistry / Febs. 222: 721-6. PMID 7517864 DOI: 10.1111/j.1432-1033.1994.tb18917.x  0.613
1994 Wijmenga SS, Heus HA, Werten B, van der Marel GA, van Boom JH, Hilbers CW. Assignment strategies and analysis of cross-peak patterns and intensities in the three-dimensional homonuclear TOCSY-NOESY of RNA. Journal of Magnetic Resonance. Series B. 103: 134-41. PMID 7511032 DOI: 10.1006/jmrb.1994.1021  0.657
1993 Zhang H, Gao YG, van der Marel GA, van Boom JH, Wang AH. Simultaneous incorporations of two anticancer drugs into DNA. The structures of formaldehyde-cross-linked adducts of daunorubicin-d(CG(araC)GCG) and doxorubicin-d(CA(araC)GTG) complexes at high resolution. The Journal of Biological Chemistry. 268: 10095-101. PMID 8486678  0.344
1993 Zuurmond HM, Veeneman GH, van der Marel GA, van Boom JH. Iodonium ion-assisted synthesis of a haptenic tetrasaccharide fragment corresponding to the inner cell-wall glycopeptidolipid of Mycobacterium avium serotype 4. Carbohydrate Research. 241: 153-64. PMID 8472251  0.349
1993 Folkers PJ, van Duynhoven JP, van Lieshout HT, Harmsen BJ, van Boom JH, Tesser GI, Konings RN, Hilbers CW. Exploring the DNA binding domain of gene V protein encoded by bacteriophage M13 with the aid of spin-labeled oligonucleotides in combination with 1H-NMR. Biochemistry. 32: 9407-16. PMID 8396429 DOI: 10.1021/Bi00087A020  0.581
1993 Tabernero L, Verdaguer N, Coll M, Fita I, van der Marel GA, van Boom JH, Rich A, Aymamí J. Molecular structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor groove binding drug netropsin. Biochemistry. 32: 8403-10. PMID 8395202 DOI: 10.1021/Bi00084A004  0.622
1993 Yang D, Gao Y, Robinson H, van der Marel GA, van Boom JH, Wang AH. Structural effects of the C2-methylhypoxanthine:cytosine base pair in B-DNA: A combined NMR and X-ray diffraction study of d(CGC[m2I]AATTCGCG). Biochemistry. 32: 8672-81. PMID 8357809  0.577
1993 Jaishree TN, van der Marel GA, van Boom JH, Wang AH. Structural influence of RNA incorporation in DNA: quantitative nuclear magnetic resonance refinement of d(CG)r(CG)d(CG) and d(CG)r(C)d(TAGCG). Biochemistry. 32: 4903-11. PMID 7683912  0.589
1992 Cognet JA, Gabarro-Arpa J, Le Bret M, van der Marel GA, van Boom JH, Fazakerley GV. Solution conformation of an oligonucleotide containing a G.G mismatch determined by nuclear magnetic resonance and molecular mechanics. Nucleic Acids Research. 19: 6771-9. PMID 1837078 DOI: 10.1093/NAR/19.24.6771  0.557
1992 Vink C, Yeheskiely E, van der Marel GA, van Boom JH, Plasterk RH. Site-specific hydrolysis and alcoholysis of human immunodeficiency virus DNA termini mediated by the viral integrase protein. Nucleic Acids Research. 19: 6691-8. PMID 1662361 DOI: 10.1093/NAR/19.24.6691  0.426
1992 Kellenbach ER, Remerowski ML, Eib D, Boelens R, van der Marel GA, van den Elst H, van Boom JH, Kaptein R. Synthesis of isotope labeled oligonucleotides and their use in an NMR study of a protein-DNA complex. Nucleic Acids Research. 20: 653-7. PMID 1542561 DOI: 10.1093/Nar/20.4.653  0.494
1992 Dreef-Tromp CM, van der Maarel JC, van den Elst H, van der Marel GA, van Boom JH. Solid-phase synthesis of the nucleopeptide fragment H-Asp-Ser[pAAAGTAAGCC]-Glu-OH from the nucleoprotein of Bacillus subtilis phage phi 29. Nucleic Acids Research. 20: 4015-20. PMID 1508685  0.474
1992 Dreef CE, Jansze JP, Elie CJ, van der Marel GA, van Boom JH. Synthesis of racemic 5-phosphonate analogues of myo-inositol 1,4,5-tris- and 1,3,4,5-tetrakis-phosphate. Carbohydrate Research. 234: 37-50. PMID 1468080  0.367
1992 Zhang H, van der Marel GA, van Boom JH, Wang AH. Conformational perturbation of the anticancer nucleotide arabinosylcytosine on Z-DNA: molecular structure of (araC-dG)3 at 1.3 A resolution. Biopolymers. 32: 1559-69. PMID 1457732 DOI: 10.1002/bip.360321113  0.564
1992 Robinson H, van der Marel GA, van Boom JH, Wang AH. Unusual DNA conformation at low pH revealed by NMR: parallel-stranded DNA duplex with homo base pairs. Biochemistry. 31: 10510-7. PMID 1420168  0.554
1992 Schmieder P, Ippel JH, van den Elst H, van der Marel GA, van Boom JH, Altona C, Kessler H. Heteronuclear NMR of DNA with the heteronucleus in natural abundance: facilitated assignment and extraction of coupling constants. Nucleic Acids Research. 20: 4747-51. PMID 1408787 DOI: 10.1093/Nar/20.18.4747  0.644
1992 Sriram M, van der Marel GA, Roelen HL, van Boom JH, Wang AH. Structural consequences of a carcinogenic alkylation lesion on DNA: effect of O6-ethylguanine on the molecular structure of the d(CGC[e6G]AATTCGCG)-netropsin complex. Biochemistry. 31: 11823-34. PMID 1332773  0.57
1992 Dreef-Tromp CM, van den Elst H, van den Boogaart JE, van der Marel GA, van Boom JH. Solid-phase synthesis of an RNA nucleopeptide fragment from the nucleoprotein of poliovirus. Nucleic Acids Research. 20: 2435-9. PMID 1317954  0.442
1991 Ohishi H, Kunisawa S, van der Marel G, van Boom JH, Rich A, Wang AH, Tomita K, Hakoshima T. Interaction between the left-handed Z-DNA and polyamine. The crystal structure of the d(CG)3 and N-(2-aminoethyl)-1,4-diamino-butane complex. Febs Letters. 284: 238-44. PMID 2060642 DOI: 10.1016/0014-5793(91)80694-X  0.629
1991 Gao YG, Liaw YC, Li YK, van der Marel GA, van Boom JH, Wang AH. Facile formation of a crosslinked adduct between DNA and the daunorubicin derivative MAR70 mediated by formaldehyde: molecular structure of the MAR70-d(CGTnACG) covalent adduct. Proceedings of the National Academy of Sciences of the United States of America. 88: 4845-9. PMID 2052564 DOI: 10.1073/PNAS.88.11.4845  0.58
1991 Xodo LE, Manzini G, Quadrifoglio F, van der Marel G, van Boom J. DNA hairpin loops in solution. Correlation between primary structure, thermostability and reactivity with single-strand-specific nuclease from mung bean. Nucleic Acids Research. 19: 1505-11. PMID 2027758 DOI: 10.1093/NAR/19.7.1505  0.553
1991 Roelen HC, Bijsterbosch MK, Bakkeren HF, van Berkel TJ, Kempen HJ, Buytenhek M, van der Marel GA, van Boom JH. Water-soluble cholesteryl-containing phosphorothioate monogalactosides: synthesis, properties, and use in lowering blood cholesterol by directing plasma lipoproteins to the liver. Journal of Medicinal Chemistry. 34: 1036-42. PMID 2002447 DOI: 10.1021/jm00107a024  0.35
1991 Xodo LE, Manzini G, Quadrifoglio F, van der Marel GA, van Boom JH. Effect of 5-methylcytosine on the stability of triple-stranded DNA--a thermodynamic study. Nucleic Acids Research. 19: 5625-31. PMID 1945840 DOI: 10.1093/NAR/19.20.5625  0.492
1991 Blommers MJ, van de Ven FJ, van der Marel GA, van Boom JH, Hilbers CW. The three-dimensional structure of a DNA hairpin in solution two-dimensional NMR studies and structural analysis of d(ATCCTATTTATAGGAT). European Journal of Biochemistry / Febs. 201: 33-51. PMID 1915376 DOI: 10.1111/J.1432-1033.1991.TB16253.X  0.7
1991 Gao YG, van der Marel GA, van Boom JH, Wang AH. Molecular structure of a DNA decamber containing an anticancer nucleoside arabinosylcytosine: conformational perturbation by arabinosylcytosine in B-DNA. Biochemistry. 30: 9922-31. PMID 1911784 DOI: 10.1021/BI00105A016  0.588
1991 Verheul AF, Boons GJ, Van der Marel GA, Van Boom JH, Jennings HJ, Snippe H, Verhoef J, Hoogerhout P, Poolman JT. Minimal oligosaccharide structures required for induction of immune responses against meningococcal immunotype L1, L2, and L3,7,9 lipopolysaccharides determined by using synthetic oligosaccharide-protein conjugates. Infection and Immunity. 59: 3566-73. PMID 1910006  0.385
1991 Roelen HC, Saris CP, Brugghe HF, van den Elst H, Westra JG, van der Marel GA, van Boom JH. Solid-phase synthesis of DNA fragments containing the modified base 7-hydro-8-oxo-2'-deoxyguanosine. Nucleic Acids Research. 19: 4361-9. PMID 1886763 DOI: 10.1093/nar/19.16.4361  0.465
1991 Koning TM, Boelens R, van der Marel GA, van Boom JH, Kaptein R. Structure determination of a DNA octamer in solution by NMR spectroscopy. Effect of fast local motions. Biochemistry. 30: 3787-97. PMID 1849738 DOI: 10.1021/Bi00229A028  0.522
1991 Remerowski ML, Kellenbach E, Boelens R, van der Marel GA, van Boom JH, Maler BA, Yamamoto KR, Kaptein R. 1H NMR studies of DNA recognition by the glucocorticoid receptor: complex of the DNA binding domain with a half-site response element. Biochemistry. 30: 11620-4. PMID 1751485 DOI: 10.1021/Bi00114A003  0.535
1990 Haasnoot CA, Westerink HP, van der Marel GA, van Boom JH. Discrimination between A-type and B-type conformations of double helical nucleic acid fragments in solution by means of two-dimensional nuclear Overhauser experiments. Journal of Biomolecular Structure & Dynamics. 2: 345-60. PMID 6400940 DOI: 10.1080/07391102.1984.10507572  0.828
1990 Haasnoot CA, Westerink HP, van der Marel GA, van Boom JH. Conformational analysis of a hybrid DNA-RNA double helical oligonucleotide in aqueous solution: d(CG)r(CG)d(CG) studied by 1D- and 2D-1H NMR spectroscopy. Journal of Biomolecular Structure & Dynamics. 1: 131-49. PMID 6086057 DOI: 10.1080/07391102.1983.10507430  0.846
1990 Manzini G, Xodo LE, Quadrifoglio F, van Boom JH, van der Marel GA. dC-dG alternating oligonucleotides: thermodynamic and kinetic aspects of the B-Z transformation. Journal of Biomolecular Structure & Dynamics. 4: 651-62. PMID 3271458 DOI: 10.1080/07391102.1987.10507666  0.475
1990 Liaw YC, Gao YG, Robinson H, van der Marel GA, van Boom JH, Wang AH. Antitumor drug nogalamycin binds DNA in both grooves simultaneously: molecular structure of nogalamycin-DNA complex. Biochemistry. 28: 9913-8. PMID 2620066 DOI: 10.1021/BI00452A006  0.539
1990 Robinson H, Liaw YC, van der Marel GA, van Boom JH, Wang AH. NMR studies on the binding of antitumor drug nogalamycin to DNA hexamer d(CGTACG). Nucleic Acids Research. 18: 4851-8. PMID 2395646 DOI: 10.1093/NAR/18.16.4851  0.563
1990 van Belkum A, Blommers MJ, van den Elst H, van Boom JH, Hilbers CW. Biochemical and biophysical studies on the folding of the core region of the origin of replication of bacteriophage M13. Nucleic Acids Research. 18: 4703-10. PMID 2395637 DOI: 10.1093/Nar/18.16.4703  0.587
1990 Manzini G, Xodo LE, Gasparotto D, Quadrifoglio F, van der Marel GA, van Boom JH. Triple helix formation by oligopurine-oligopyrimidine DNA fragments. Electrophoretic and thermodynamic behavior. Journal of Molecular Biology. 213: 833-43. PMID 2359124 DOI: 10.1016/S0022-2836(05)80267-0  0.529
1990 Frederick CA, Williams LD, Ughetto G, van der Marel GA, van Boom JH, Rich A, Wang AH. Structural comparison of anticancer drug-DNA complexes: adriamycin and daunomycin. Biochemistry. 29: 2538-49. PMID 2334681 DOI: 10.1021/Bi00462A016  0.633
1990 Aymami J, Coll M, van der Marel GA, van Boom JH, Wang AH, Rich A. Molecular structure of nicked DNA: a substrate for DNA repair enzymes. Proceedings of the National Academy of Sciences of the United States of America. 87: 2526-30. PMID 2320572 DOI: 10.1073/Pnas.87.7.2526  0.648
1990 Williams LD, Egli M, Qi G, Bash P, van der Marel GA, van Boom JH, Rich A, Frederick CA. Structure of nogalamycin bound to a DNA hexamer. Proceedings of the National Academy of Sciences of the United States of America. 87: 2225-9. PMID 2315315 DOI: 10.1073/Pnas.87.6.2225  0.633
1990 Lamerichs RM, Boelens R, Van der Marel GA, Van Boom JH, Kaptein R. Assignment of the 1H-NMR spectrum of a lac repressor headpiece-operator complex in H2O and identification of NOEs. Consequences for protein-DNA interaction. European Journal of Biochemistry / Febs. 194: 629-37. PMID 2269288 DOI: 10.1111/J.1432-1033.1990.Tb15662.X  0.508
1990 Blommers MJ, Slot HJ, van der Marel GA, van Boom JH, Hilbers CW. Conformational analysis of the 3'-5'-cyclic dinucleotide d less than pApA greater than by means of molecular mechanics. Journal of Biomolecular Structure & Dynamics. 8: 233-51. PMID 2176505 DOI: 10.1080/07391102.1990.10507804  0.681
1990 Liaw YC, Gao YG, Robinson H, Sheldrick GM, Sliedregt LA, van der Marel GA, van Boom JH, Wang AH. Cyclic diguanylic acid behaves as a host molecule for planar intercalators. Febs Letters. 264: 223-7. PMID 2162785 DOI: 10.1016/0014-5793(90)80253-F  0.489
1990 Pieters JM, de Vroom E, van der Marel GA, van Boom JH, Koning TM, Kaptein R, Altona C. Hairpin structures in DNA containing arabinofuranosylcytosine. A combination of nuclear magnetic resonance and molecular dynamics. Biochemistry. 29: 788-99. PMID 2159791 DOI: 10.1021/Bi00455A029  0.69
1990 Egli M, Gessner RV, Williams LD, Quigley GJ, van der Marel GA, van Boom JH, Rich A, Frederick CA. Atomic-resolution structure of the cellulose synthase regulator cyclic diguanylic acid. Proceedings of the National Academy of Sciences of the United States of America. 87: 3235-9. PMID 2158107 DOI: 10.1073/Pnas.87.8.3235  0.566
1990 Williams LD, Egli M, Ughetto G, van der Marel GA, van Boom JH, Quigley GJ, Wang AH, Rich A, Frederick CA. Structure of 11-deoxydaunomycin bound to DNA containing a phosphorothioate. Journal of Molecular Biology. 215: 313-20. PMID 2152325 DOI: 10.1016/S0022-2836(05)80349-3  0.616
1990 Dreef-Tromp CM, van Dam EM, van den Elst H, van der Marel GA, van Boom JH. Solid-phase synthesis of H-Phe-Tyr-(pATAT)-NH2: a nucleopeptide fragment from the nucleoprotein of bacteriophage phi X174. Nucleic Acids Research. 18: 6491-5. PMID 2147473 DOI: 10.1093/nar/18.22.6491  0.402
1990 Noort D, Coughtrie MW, Burchell B, van der Marel GA, van Boom JH, van der Gen A, Mulder GJ. Inhibition of UDP-glucuronosyltransferase activity by possible transition-state analogues in rat-liver microsomes. European Journal of Biochemistry / Febs. 188: 309-12. PMID 2108023 DOI: 10.1111/J.1432-1033.1990.Tb15404.X  0.36
1990 Carter BJ, De Vroom E, Long EC, Van Der Marel GA, Van Boom JH, Hecht SM. Site-specific cleavage of RNA by Fe(II)·bleomycin Proceedings of the National Academy of Sciences of the United States of America. 87: 9373-9377. PMID 1701259 DOI: 10.1073/Pnas.87.23.9373  0.415
1989 Xodo LE, Manzini G, Quadrifoglio F, van der Marel GA, van Boom JH. The B-Z conformational transition in folded oligodeoxynucleotides: loop size and stability of Z-hairpins. Biochemistry. 27: 6327-31. PMID 3219338 DOI: 10.1021/BI00417A019  0.531
1989 Xodo LE, Manzini G, Quadrifoglio F, van der Marel GA, van Boom JH. Oligodeoxynucleotide folding in solution: loop size and stability of B-hairpins. Biochemistry. 27: 6321-6. PMID 3219337 DOI: 10.1021/BI00417A018  0.548
1989 Xodo LE, Manzini G, Quadrifoglio F, Yathindra N, van der Marel GA, van Boom JH. A facile duplex-hairpin interconversion through a cruciform intermediate in a linear DNA fragment. Journal of Molecular Biology. 205: 777-81. PMID 2926824 DOI: 10.1016/0022-2836(89)90322-7  0.553
1989 Blommers MJ, Walters JA, Haasnoot CA, Aelen JM, van der Marel GA, van Boom JH, Hilbers CW. Effects of base sequence on the loop folding in DNA hairpins. Biochemistry. 28: 7491-8. PMID 2819083 DOI: 10.1021/BI00444A049  0.819
1989 Wang AH, Cottens S, Dervan PB, Yesinowski JP, van der Marel GA, van Boom JH. Interactions between a symmetrical minor groove binding compound and DNA oligonucleotides: 1H and 19F NMR studies. Journal of Biomolecular Structure & Dynamics. 7: 101-17. PMID 2818866 DOI: 10.1080/07391102.1989.10507754  0.485
1989 Xodo LE, Manzini G, Quadrifoglio F, Yathindra N, van der Marel GA, van Boom JH. The left-handed Z-DNA conformation in oligodeoxynucleotides containing different amounts of AT base pairs: a far UV circular dichroism study. Journal of Biomolecular Structure & Dynamics. 6: 1217-31. PMID 2818863 DOI: 10.1080/07391102.1989.10506546  0.493
1989 Hua N, van der Marel GA, van Boom JH, Feigon J. Non-contiguous regions of Z-DNA in a DNA dodecamer. Nucleic Acids Research. 17: 7923-44. PMID 2798135 DOI: 10.1093/Nar/17.19.7923  0.55
1989 Pieters JM, de Vroom E, van der Marel GA, van Boom JH, Altona C. Conformational consequences of the incorporation of arabinofuranosylcytidine in DNA. An NMR study of the DNA fragments d(CGCTAGCG) and d(CGaCTAGCG) in solution. European Journal of Biochemistry / Febs. 184: 415-25. PMID 2792106 DOI: 10.1111/J.1432-1033.1989.Tb15033.X  0.706
1989 Pieters JM, Mans RM, van den Elst H, van der Marel GA, van Boom JH, Altona C. Conformational and thermodynamic consequences of the introduction of a nick in duplexed DNA fragments: an NMR study augmented by biochemical experiments. Nucleic Acids Research. 17: 4551-65. PMID 2748334 DOI: 10.1093/nar/17.12.4551  0.652
1989 Lamerichs RM, Boelens R, van der Marel GA, van Boom JH, Kaptein R, Buck F, Fera B, Rüterjans H. H NMR study of a complex between the lac repressor headpiece and a 22 base pair symmetric lac operator. Biochemistry. 28: 2985-91. PMID 2742823 DOI: 10.1021/Bi00433A037  0.496
1989 Kuyl-Yeheskiely E, Dreef-Tromp CM, Geluk A, van der Marel GA, van Boom JH. Synthesis of the nucleopeptides H-Phe-Tyr(pGC)-NH2 and H-Phe-Ser(pGC)-Ala-OH via a phosphotriester approach. Nucleic Acids Research. 17: 2897-905. PMID 2726447 DOI: 10.1093/nar/17.8.2897  0.42
1989 Gilbert DE, van der Marel GA, van Boom JH, Feigon J. Unstable Hoogsteen base pairs adjacent to echinomycin binding sites within a DNA duplex. Proceedings of the National Academy of Sciences of the United States of America. 86: 3006-10. PMID 2717609 DOI: 10.1073/Pnas.86.9.3006  0.573
1989 Frederick CA, Quigley GJ, Teng MK, Coll M, Van der Marel GA, Van Boom JH, Rich A, Wang AH. Molecular structure of an A-DNA decamer d(ACCGGCCGGT). European Journal of Biochemistry / Febs. 181: 295-307. PMID 2714286 DOI: 10.1111/J.1432-1033.1989.Tb14724.X  0.65
1989 Pieters JM, Mellema JR, van den Elst H, van der Marel GA, van Boom JH, Altona C. Thermodynamics of the various forms of the dodecamer d(ATTACCGGTAAT) and of its constituent hexamers from proton nmr chemical shifts and UV melting curves: three-state and four-state thermodynamic models. Biopolymers. 28: 717-40. PMID 2706311 DOI: 10.1002/bip.360280304  0.685
1989 Benevides JM, Wang AH, van der Marel GA, van Boom JH, Thomas GJ. Effect of the G.T mismatch on backbone and sugar conformations of Z-DNA and B-DNA: analysis by Raman spectroscopy of crystal and solution structures of d(CGCGTG) and d(CGCGCG). Biochemistry. 28: 304-10. PMID 2706254 DOI: 10.1021/BI00427A041  0.562
1989 Boons GJ, Overhand M, van der Marel GA, van Boom JH. Synthesis of a trisaccharide of the inner core region of Citrobacter PCM 187 lipopolysaccharide that contains L-glycero-alpha-D-manno-heptopyranosyl units. Carbohydrate Research. 192: C1-4. PMID 2611773 DOI: 10.1016/0008-6215(89)85198-5  0.553
1989 Coll M, Aymami J, van der Marel GA, van Boom JH, Rich A, Wang AH. Molecular structure of the netropsin-d(CGCGATATCGCG) complex: DNA conformation in an alternating AT segment. Biochemistry. 28: 310-20. PMID 2539859 DOI: 10.1021/Bi00427A042  0.646
1989 Xodo LE, Manzini G, Quadrifoglio F, van der Marel G, van Boom JH. Hairpin structures in synthetic oligodeoxynucleotides: sequence effects on the duplex-to-hairpin transition. Biochimie. 71: 793-803. PMID 2505860 DOI: 10.1016/0300-9084(89)90042-4  0.551
1989 Tomita K, Hakoshima T, Inubushi K, Kunisawa S, Ohishi H, van der Marel GA, van Boom JH, Wang AH, Rich A. Polyamine interaction with Z-DNA. Journal of Molecular Graphics. 7: 71-5. PMID 2488266 DOI: 10.1016/S0263-7855(89)80002-5  0.597
1989 Carrondo MA, Coll M, Aymami J, Wang AH, van der Marel GA, van Boom JH, Rich A. Binding of a Hoechst dye to d(CGCGATATCGCG) and its influence on the conformation of the DNA fragment. Biochemistry. 28: 7849-59. PMID 2482071 DOI: 10.1021/Bi00445A047  0.645
1989 Teng MK, Liaw YC, van der Marel GA, van Boom JH, Wang AH. Effects of the O2' hydroxyl group on Z-DNA conformation: structure of Z-RNA and (araC)-[Z-DNA]. Biochemistry. 28: 4923-8. PMID 2475172 DOI: 10.1021/BI00438A001  0.575
1988 Roelen HC, de Vroom E, van der Marel GA, van Boom JH. Synthesis of nucleic acid methylphosphonothioates. Nucleic Acids Research. 16: 7633-45. PMID 3412896 DOI: 10.1093/nar/16.15.7633  0.45
1988 van den Hoogen YT, van Beuzekom AA, de Vroom E, van der Marel GA, van Boom JH, Altona C. Bulge-out structures in the single-stranded trimer AUA and in the duplex (CUGGUGCGG).(CCGCCCAG). A model-building and NMR study. Nucleic Acids Research. 16: 5013-30. PMID 3387215 DOI: 10.1093/nar/16.11.5013  0.668
1988 de Vroom E, Broxterman HJ, Sliedregt LA, van der Marel GA, van Boom JH. Synthesis of cyclic oligonucleotides by a modified phosphotriester approach. Nucleic Acids Research. 16: 4607-20. PMID 3380690 DOI: 10.1093/nar/16.10.4607  0.445
1988 van den Hoogen YT, van Beuzekom AA, van den Elst H, van der Marel GA, van Boom JH, Altona C. Extra thymidine stacks into the d(CTGGTGCGG).d(CCGCCCAG) duplex. An NMR and model-building study. Nucleic Acids Research. 16: 2971-86. PMID 3368313 DOI: 10.1093/nar/16.7.2971  0.698
1988 Benevides JM, Wang AH, van der Marel GA, van Boom JH, Thomas GJ. Crystal and solution structures of the B-DNA dodecamer d(CGCAAATTTGCG) probed by Raman spectroscopy: heterogeneity in the crystal structure does not persist in the solution structure. Biochemistry. 27: 931-8. PMID 3365372 DOI: 10.1021/BI00403A014  0.533
1988 Kemmink J, Eker APM, van der Marel GA, van Boom JH, Kaptein R. Photoreactivation of the thymine dimer containing DNA octamer d(GCGT TGCG)·d(CGCAACGC) by the photoreactivating enzyme from Anacystis nidulans Journal of Photochemistry and Photobiology, B: Biology. 1: 323-328. PMID 3149667 DOI: 10.1016/1011-1344(88)85020-6  0.532
1988 van den Hoogen YT, Treurniet SJ, Roelen HC, de Vroom E, van der Marel GA, van Boom JH, Altona C. Conformational analysis of the tetranucleotides m6(2)A-m6(2)A-U-m6(2)A(m6(2)A = N6-dimethyladenosine) and U-m6(2)A-U-m6(2)A and of the hybrid dA-r(U-A). A one- and two-dimensional NMR study. European Journal of Biochemistry / Febs. 171: 155-62. PMID 3123229 DOI: 10.1111/J.1432-1033.1988.TB13771.X  0.595
1988 van den Hoogen YT, Lankhorst PP, Gijsman P, Hartel AJ, van Boom JH, Altona C. Conformational analysis of the dinucleotides 5'-methylphospho-N6-dimethyladenylyl-uridine (mpm62A-U) and 5'methylphospho-uridylyl-N6-dimethyladenosine (mpU-m62A) and of the trinucleotide U-m62A-U. A nuclear magnetic resonance and circular dichroic study. European Journal of Biochemistry / Febs. 171: 143-53. PMID 3123228 DOI: 10.1111/J.1432-1033.1988.Tb13770.X  0.535
1988 Blommers MJ, Haasnoot CA, Walters JA, van der Marel GA, van Boom JH, Hilbers CW. Solution structure of the 3'-5' cyclic dinucleotide d(pApA). A combined NMR, UV melting, and molecular mechanics study. Biochemistry. 27: 8361-9. PMID 2853963 DOI: 10.1021/BI00422A011  0.827
1988 Frederick CA, Coll M, van der Marel GA, van Boom JH, Wang AH. Molecular structure of cyclic deoxydiadenylic acid at atomic resolution. Biochemistry. 27: 8350-61. PMID 2853962 DOI: 10.1021/BI00422A010  0.527
1988 Frederick CA, Quigley GJ, van der Marel GA, van Boom JH, Wang AH, Rich A. Methylation of the EcoRI recognition site does not alter DNA conformation: the crystal structure of d(CGCGAm6ATTCGCG) at 2.0-A resolution. The Journal of Biological Chemistry. 263: 17872-9. PMID 2846582 DOI: 10.2210/Pdb4Dnb/Pdb  0.624
1988 Baumann U, Lehmann U, Schwellnus K, van Boom JH, Kuhn H. Complexes of DNA hairpins and a single-stranded oligonucleotide detected by affinity chromatography and mung bean nuclease cleavage. European Journal of Biochemistry. 170: 267-72. PMID 2826156 DOI: 10.1111/J.1432-1033.1987.TB13695.X  0.304
1988 de Vroom E, Roelen HC, Saris CP, Budding TN, van der Marel GA, van Boom JH. Preparation of covalently linked DNA-RNA hybrids and arabinocytidine containing DNA fragments. Nucleic Acids Research. 16: 2987-3003. PMID 2453027 DOI: 10.1093/nar/16.7.2987  0.494
1988 van den Hoogen YT, Erkelens C, de Vroom E, van der Marel GA, van Boom JH, Altona C. Influence of uracil on the conformational behaviour of RNA oligonucleotides in solution. European Journal of Biochemistry / Febs. 173: 295-303. PMID 2452087 DOI: 10.1111/J.1432-1033.1988.Tb13998.X  0.713
1988 Sugiyama H, Xu C, Murugesan N, Hecht SM, van der Marel GA, van Boom JH. Chemistry of the alkali-labile lesion formed from iron(II) bleomycin and d(CGCTTTAAAGCG). Biochemistry. 27: 58-67. PMID 2450572 DOI: 10.1021/Bi00401A011  0.467
1987 de Vroom E, Fidder A, Saris CP, van der Marel GA, van Boom JH. Preparation of the individual diastereomers of adenylyl-(2'-5')-P-thioadenylyl-(2'-5')-adenosine and their 5'-phosphorylated derivatives. Nucleic Acids Research. 15: 9933-43. PMID 3697086 DOI: 10.1093/nar/15.23.9933  0.36
1987 Orbons LP, van der Marel GA, van Boom JH, Altona C. An NMR study of polymorphous behaviour of the mismatched DNA octamer d(m5C-G-m5C-G-A-G-m5C-G) in solution. The B-duplex and hairpin forms. European Journal of Biochemistry / Febs. 170: 225-39. PMID 3691520 DOI: 10.1111/J.1432-1033.1987.Tb13690.X  0.7
1987 Frederick CA, Saal D, van der Marel GA, van Boom JH, Wang AH, Rich A. The crystal structure of d(GGm5CCGGCC): the effect of methylation on A-DNA structure and stability. Biopolymers. 26: S145-60. PMID 3580495 DOI: 10.1002/bip.360260014  0.641
1987 Orbons LP, van der Marel GA, van Boom JH, Altona C. An NMR study of the polymorphous behavior of the mismatched DNA octamer d(m5C-G-m5C-G-T-G-m5C-G) in solution. The B, Z, and hairpin forms. Journal of Biomolecular Structure & Dynamics. 4: 939-63. PMID 3270540 DOI: 10.1080/07391102.1987.10507691  0.698
1987 Kuyl-Yeheskiely E, Tromp CM, Schaeffer AH, van der Marel GA, van Boom JH. A model study directed towards the preparation of nucleopeptides via H-phosphonate intermediates. Nucleic Acids Research. 15: 1807-18. PMID 3103103 DOI: 10.1093/NAR/15.4.1807  0.445
1987 Rinkel LJ, van der Marel GA, van Boom JH, Altona C. Influence of the base sequence on the conformational behaviour of DNA polynucleotides in solution. European Journal of Biochemistry / Febs. 166: 87-101. PMID 3036527 DOI: 10.1111/J.1432-1033.1987.Tb13487.X  0.712
1987 Kemmink J, Boelens R, Koning T, van der Marel GA, van Boom JH, Kaptein R. 1H NMR study of the exchangeable protons of the duplex d(GCGTTGCG).d(CGCAACGC) containing a thymine photodimer. Nucleic Acids Research. 15: 4645-53. PMID 3035498 DOI: 10.1093/Nar/15.11.4645  0.548
1987 Quignard E, Fazakerley GV, van der Marel G, van Boom JH, Guschlbauer W. Comparison of the conformation of an oligonucleotide containing a central G-T base pair with the non-mismatch sequence by proton NMR. Nucleic Acids Research. 15: 3397-409. PMID 3033602 DOI: 10.1093/NAR/15.8.3397  0.522
1987 Rinkel LJ, van der Marel GA, van Boom JH, Altona C. Influence of N6-methylation of residue A(5) on the conformational behaviour of d(C-C-G-A-A-T-T-C-G-G) in solution studied by 1H-NMR spectroscopy. 2. The hairpin form. European Journal of Biochemistry / Febs. 163: 287-96. PMID 3028801  0.677
1987 Rinkel LJ, van der Marel GA, van Boom JH, Altona C. Influence of N6-methylation of residue A(5) on the conformational behaviour of d(C-C-G-A-A-T-T-C-G-G) in solution studied by 1H-NMR spectroscopy. 1. The duplex form. European Journal of Biochemistry / Febs. 163: 275-86. PMID 3028800 DOI: 10.1111/J.1432-1033.1987.Tb10798.X  0.714
1987 Kemmink J, Boelens R, Koning TM, Kaptein R, van der Marel GA, van Boom JH. Conformational changes in the oligonucleotide duplex d(GCGTTGCG) x d(CGCAACGC) induced by formation of a cis-syn thymine dimer. A two-dimensional NMR study. European Journal of Biochemistry / Febs. 162: 37-43. PMID 3028790 DOI: 10.1111/J.1432-1033.1987.Tb10538.X  0.591
1987 Raap J, Dreef CE, van der Marel GA, van Boom JH, Hilbers CW. Synthesis and proton-NMR studies of oligonucleotides containing an apurinic (AP) site. Journal of Biomolecular Structure & Dynamics. 5: 219-47. PMID 2856028 DOI: 10.1080/07391102.1987.10506391  0.837
1987 Ehrenfeld GM, Shipley JB, Heimbrook DC, Sugiyama H, Long EC, Van Boom JH, Van Der Marel GA, Oppenheimer NJ, Hecht SM. Copper-dependent cleavage of DNA by bleomycin Biochemistry. 26: 931-942. PMID 2436656 DOI: 10.1021/Bi00377A038  0.395
1986 Benevides JM, Wang AH, Rich A, Kyogoku Y, van der Marel GA, van Boom JH, Thomas GJ. Raman spectra of single crystals of r(GCG)d(CGC) and d(CCCCGGGG) as models for A DNA, their structure transitions in aqueous solution, and comparison with double-helical poly(dG).poly(dC). Biochemistry. 25: 41-50. PMID 3954991 DOI: 10.1021/Bi00349A007  0.666
1986 Orbons LP, van der Marel GA, van Boom JH, Altona C. Hairpin and duplex formation of the DNA octamer d(m5C-G-m5C-G-T-G-m5C-G) in solution. An NMR study. Nucleic Acids Research. 14: 4187-96. PMID 3714474 DOI: 10.1093/nar/14.10.4187  0.683
1986 Quigley GJ, Ughetto G, van der Marel GA, van Boom JH, Wang AH, Rich A. Non-Watson-Crick G.C and A.T base pairs in a DNA-antibiotic complex. Science (New York, N.Y.). 232: 1255-8. PMID 3704650 DOI: 10.1126/Science.3704650  0.65
1986 Marugg JE, de Vroom E, Dreef CE, Tromp M, van der Marel GA, van Boom JH. Synthesis of nucleic acid methylphosphonates via the 1-hydroxybenzotriazole phosphotriester approach. Nucleic Acids Research. 14: 2171-85. PMID 3457366 DOI: 10.1093/NAR/14.5.2171  0.449
1986 Coll M, Wang AH, van der Marel GA, van Boom JH, Rich A. Crystal structure of a Z-DNA fragment containing thymine/2-aminoadenine base pairs. Journal of Biomolecular Structure & Dynamics. 4: 157-72. PMID 3271437 DOI: 10.1080/07391102.1986.10506337  0.663
1986 Orbons LP, van der Marel GA, van Boom JH, Altona C. The B and Z forms of the d(m5C-G)3 and d(br5C-G)3 hexamers in solution. A 300-MHz and 500-MHz two-dimensional NMR study. European Journal of Biochemistry / Febs. 160: 131-9. PMID 3021446 DOI: 10.1111/J.1432-1033.1986.Tb09949.X  0.665
1986 Rinkel LJ, Sanderson MR, van der Marel GA, van Boom JH, Altona C. Conformational analysis of the octamer d(G-G-C-C-G-G-C-C) in aqueous solution. A one-dimensional and two-dimensional proton NMR study at 300 MHz and 500 MHz. European Journal of Biochemistry / Febs. 159: 85-93. PMID 3017719 DOI: 10.1111/J.1432-1033.1986.Tb09836.X  0.683
1986 Rinkel LJ, Mellema JR, van der Marel GA, van Boom JH, Altona C. Influence of 2-aminoadenosine, A', on the conformational behaviour of d(T-A'-T-A'). A one-dimensional proton NMR study at 300 MHz and 500 MHz. European Journal of Biochemistry / Febs. 154: 259-65. PMID 3002796 DOI: 10.1111/J.1432-1033.1986.Tb09391.X  0.699
1986 Haasnoot CA, Hilbers CW, van der Marel GA, van Boom JH, Singh UC, Pattabiraman N, Kollman PA. On loop folding in nucleic acid hairpin-type structures. Journal of Biomolecular Structure & Dynamics. 3: 843-57. PMID 2482747 DOI: 10.1080/07391102.1986.10508468  0.822
1986 de Vroom E, Fidder A, Marugg JE, van der Marel GA, van Boom JH. Use of a 1-hydroxybenzotriazole activated phosphorylating reagent towards the synthesis of short RNA fragments in solution. Nucleic Acids Research. 14: 5885-900. PMID 2426660 DOI: 10.1093/NAR/14.14.5885  0.427
1985 Fazakerley GV, van der Marel GA, van Boom JH, Guschlbauer W. Helix opening in deoxyribonucleic acid from a proton nuclear magnetic resonance study of imino and amino protons in d(CG)3. Nucleic Acids Research. 12: 8269-79. PMID 6504700 DOI: 10.1093/NAR/12.21.8269  0.497
1985 Ho PS, Frederick CA, Quigley GJ, van der Marel GA, van Boom JH, Wang AH, Rich A. G.T wobble base-pairing in Z-DNA at 1.0 A atomic resolution: the crystal structure of d(CGCGTG). The Embo Journal. 4: 3617-23. PMID 4092690 DOI: 10.1002/J.1460-2075.1985.Tb04125.X  0.535
1985 Hilbers CW, Haasnoot CAG, de Bruin SH, Joordens JJM, Van Der Marel GA, Van Boom JH. Hairpin formation in synthetic oligonucleotides Biochimie. 67: 685-695. PMID 4084598 DOI: 10.1016/S0300-9084(85)80156-5  0.705
1985 Feigon J, Wang AH, van der Marel GA, van Boom JH, Rich A. Z-DNA forms without an alternating purine-pyrimidine sequence in solution. Science (New York, N.Y.). 230: 82-4. PMID 4035359 DOI: 10.1126/Science.4035359  0.564
1985 Schattenkerk C, Wreesmann CT, van der Marel GA, van Boom JH. Synthesis of riboguanosine pentaphosphate ppprGpp (Magic Spot II) via a phosphotriester approach. Nucleic Acids Research. 13: 3635-49. PMID 4011437 DOI: 10.1093/NAR/13.10.3635  0.357
1985 Ughetto G, Wang AH, Quigley GJ, van der Marel GA, van Boom JH, Rich A. A comparison of the structure of echinomycin and triostin A complexed to a DNA fragment. Nucleic Acids Research. 13: 2305-23. PMID 4000957 DOI: 10.1093/Nar/13.7.2305  0.626
1985 Lankhorst PP, Haasnoot CA, Erkelens C, Westerink HP, van der Marel GA, van Boom JH, Altona C. Carbon-13 NMR in conformational analysis of nucleic acid fragments. 4. The torsion angle distribution about the C3'-O3' bond in DNA constituents. Nucleic Acids Research. 13: 927-42. PMID 4000932 DOI: 10.1093/nar/13.3.927  0.822
1985 Fujii S, Wang AH, Quigley GJ, Westerink H, Van der Marel G, Van Boom JH, Rich A. The octamers d(CGCGCGCG) and d(CGCATGCG) both crystallize as Z-DNA in the same hexagonal lattice. Biopolymers. 24: 243-50. PMID 3986289 DOI: 10.1002/bip.360240118  0.617
1985 Gessner RV, Quigley GJ, Wang AH, van der Marel GA, van Boom JH, Rich A. Structural basis for stabilization of Z-DNA by cobalt hexaammine and magnesium cations. Biochemistry. 24: 237-40. PMID 3978072 DOI: 10.1021/Bi00323A001  0.608
1985 den Hartog JH, Altona C, van Boom JH, van der Marel GA, Haasnoot CA, Reedijk J. cis-diamminedichloroplatinum(II) induced distortion of a single and double stranded deoxydecanucleosidenonaphosphate studied by nuclear magnetic resonance. Journal of Biomolecular Structure & Dynamics. 2: 1137-55. PMID 3916945 DOI: 10.1080/07391102.1985.10507629  0.823
1985 Wang AH, Gessner RV, van der Marel GA, van Boom JH, Rich A. Crystal structure of Z-DNA without an alternating purine-pyrimidine sequence. Proceedings of the National Academy of Sciences of the United States of America. 82: 3611-5. PMID 3858839 DOI: 10.1073/Pnas.82.11.3611  0.65
1985 Lankhorst PP, van der Marel GA, Wille G, van Boom JH, Altona C. Conformational characteristics of the hexanucleoside pentaphosphate AUAUAU: a 2D NMR study at 500 MHz. Nucleic Acids Research. 13: 3317-33. PMID 2987882 DOI: 10.1093/nar/13.9.3317  0.685
1984 Mellema JR, van der Woerd R, van der Marel GA, van Boom JH, Altona C. Proton NMR study and conformational analysis of d(CGT), d(TCG) and d(CGTCG) in aqueous solution. The effect of a dangling thymidine and of a thymidine mismatch on DNA mini-duplexes. Nucleic Acids Research. 12: 5061-78. PMID 6739297 DOI: 10.1093/nar/12.12.5061  0.718
1984 Westerink HP, van der Marel GA, van Boom JH, Haasnoot CA. Conformational analysis of r(CGCGCG) in aqueous solution: an A-type double helical conformation studied by two-dimensional nuclear Overhauser effect spectroscopy. Nucleic Acids Research. 12: 4323-38. PMID 6728679 DOI: 10.1093/NAR/12.10.4323  0.824
1984 Wang AH, Hakoshima T, van der Marel G, van Boom JH, Rich A. AT base pairs are less stable than GC base pairs in Z-DNA: the crystal structure of d(m5CGTAm5CG). Cell. 37: 321-31. PMID 6722876 DOI: 10.1016/0092-8674(84)90328-3  0.52
1984 Tibanyenda N, De Bruin SH, Haasnoot CA, van der Marel GA, van Boom JH, Hilbers CW. The effect of single base-pair mismatches on the duplex stability of d(T-A-T-T-A-A-T-A-T-C-A-A-G-T-T-G) . d(C-A-A-C-T-T-G-A-T-A-T-T-A-A-T-A) European Journal of Biochemistry. 139: 19-27. PMID 6698006 DOI: 10.1111/J.1432-1033.1984.TB07970.X  0.794
1984 Feigon J, Wang AH, van der Marel GA, Van Boom JH, Rich A. A one- and two-dimensional NMR study of the B to Z transition of (m5dC-dG)3 in methanolic solution. Nucleic Acids Research. 12: 1243-63. PMID 6694910 DOI: 10.1093/Nar/12.2.1243  0.661
1984 Uesugi S, Ohkubo M, Ohtsuka E, Ikehara M, Kobayashi Y, Kyogoku Y, Westerink HP, van der Marel GA, van Boom JH, Haasnoot CA. Conformation of ribooligonucleotide duplexes containing an alternating C-G sequence which show an unusual circular dichroism spectrum. The Journal of Biological Chemistry. 259: 1390-3. PMID 6693410  0.801
1984 Schattenkerk C, Visser GM, van der Marel GA, van Boom JH. Synthesis of ppTppp via phosphotriester intermediates. Nucleic Acids Research. 11: 7545-54. PMID 6647028 DOI: 10.1093/NAR/11.21.7545  0.377
1984 Mellema JR, Pieters JM, van der Marel GA, van Boom JH, Haasnoot CA, Altona C. Sequence-dependent structural variation in single-helical DNA. Proton NMR studies of d(T-A-T-A) and d(A-T-A-T) in aqueous solution. European Journal of Biochemistry / Febs. 143: 285-301. PMID 6547907 DOI: 10.1111/J.1432-1033.1984.Tb08371.X  0.825
1984 den Hartog JH, Altona C, van Boom JH, Reedijk J. A phosphorus NMR study of the reaction products of cis-diamminedichloroplatinum (II) with a double-helical oligonucleotide and with DNA. Febs Letters. 176: 393-7. PMID 6541594 DOI: 10.1016/0014-5793(84)81204-1  0.61
1984 Wang AH, Ughetto G, Quigley GJ, Hakoshima T, van der Marel GA, van Boom JH, Rich A. The molecular structure of a DNA-triostin A complex. Science (New York, N.Y.). 225: 1115-21. PMID 6474168 DOI: 10.1126/Science.6474168  0.662
1984 Benevides JM, Wang AH, van der Marel GA, van Boom JH, Rich A, Thomas GJ. The Raman spectra of left-handed DNA oligomers incorporating adenine-thymine base pairs+. Nucleic Acids Research. 12: 5913-25. PMID 6462921 DOI: 10.1093/Nar/12.14.5913  0.63
1984 Mellema JR, Jellema AK, Haasnoot CA, Van Boom JH, Altona C. Conformational analysis of the single-helical DNA fragment d(T-A-A-T) in aqueous solution. The combined use of NMR proton chemical shifts and coupling constants obtained at 300 MHz and 500 MHz. European Journal of Biochemistry / Febs. 141: 165-75. PMID 6327305 DOI: 10.1111/J.1432-1033.1984.Tb08171.X  0.833
1984 Wreesmann CT, Fidder A, van der Marel GA, van Boom JH. Synthesis of short RNA fragments by the benzotriazolyl phosphotriester approach. Nucleic Acids Research. 11: 8389-405. PMID 6200828 DOI: 10.1093/NAR/11.23.8389  0.416
1984 Clore GM, Gronenborn AM, Piper EA, McLaughlin LW, Graeser E, van Boom JH. The solution structure of a RNA pentadecamer comprising the anticodon loop and stem of yeast tRNAPhe. A 500 MHz 1H-n.m.r. study. The Biochemical Journal. 221: 737-51. PMID 6089745 DOI: 10.1042/Bj2210737  0.325
1983 Fujii S, Wang AH, van der Marel G, van Boom JH, Rich A. Molecular structure of (m5 dC-dG)3: the role of the methyl group on 5-methyl cytosine in stabilizing Z-DNA. Nucleic Acids Research. 10: 7879-92. PMID 7155900 DOI: 10.1093/NAR/10.23.7879  0.627
1983 Lankhorst PP, Wille G, van Boom JH, Altona C, Haasnoot CA. Conformational analysis of a ribopentanucleoside tetraphosphate in aqueous solution. A two-dimensional NMR study at 500 MHz. Nucleic Acids Research. 11: 2839-56. PMID 6856477 DOI: 10.1093/nar/11.9.2839  0.794
1983 Sanderson MR, Mellema JR, van der Marel GA, Wille G, van Boom JH, Altona C. Assignment of non-exchangeable base proton and H1' resonances of a deoxyoctanucleoside heptaphosphate d(G-G-C*-C*-G-G-C-C) by using the nuclear Overhauser effect. Nucleic Acids Research. 11: 3333-46. PMID 6856458 DOI: 10.1093/nar/11.10.3333  0.667
1983 den Hartog JH, Altona C, van Boom JH, Marcelis AT, van der Marel GA, Rinkel LJ, Wille-Hazeleger G, Reedijk J. cis-Platinum induced distortions in DNA. Conformational analysis of d(GpCpG) and cis-pt(NH3)2[d(GpCpG)], studied by 500-MHz NMR. European Journal of Biochemistry / Febs. 134: 485-95. PMID 6684039 DOI: 10.1111/J.1432-1033.1983.Tb07593.X  0.672
1983 Hakoshima T, Wang AH, van Boom JH, Rich A. Molecular structure of d(m5CGTAm5CG): TA pairs in Z-DNA and the consequences. Nucleic Acids Symposium Series. 213-6. PMID 6664864  0.55
1983 Alma NCM, Harmsen BJM, Van Boom JH, Van Der Marel G, Hilbers CW. A 500-MHz proton nuclear magnetic resonance study of the structure and structural alterations of gene-5 protein-oligo(deoxyadenylic acid) complexes Biochemistry. 22: 2104-2115. PMID 6602628 DOI: 10.1021/BI00278A010  0.653
1983 van Boom JH, van der Marel GA, Westerink H, van Boeckel CA, Mellema JR, Altona C, Hilbers CW, Haasnoot CA, de Bruin SH, Berendsen RG. Synthesis and conformational analysis of synthetic DNA fragments. Cold Spring Harbor Symposia On Quantitative Biology. 47: 403-9. PMID 6574853  0.807
1983 Wang AH, Fujii S, van Boom JH, Rich A. Right-handed and left-handed double-helical DNA: structural studies. Cold Spring Harbor Symposia On Quantitative Biology. 33-44. PMID 6574849 DOI: 10.1101/SQB.1983.047.01.006  0.437
1983 Haasnoot CA, de Bruin SH, Berendsen RG, Janssen HG, Binnendijk TJ, Hilbers CW, van der Marel GA, van Boom JH. Structure, kinetics and thermodynamics of DNA hairpin fragments in solution. Journal of Biomolecular Structure & Dynamics. 1: 115-29. PMID 6401107 DOI: 10.1080/07391102.1983.10507429  0.824
1983 Mellema JR, Haasnoot CA, van der Marel GA, Wille G, van Boeckel CA, van Boom JH, Altona C. Proton NMR studies on the covalently linked RNA-DNA hybrid r(GCG)d(TATACGC). Assignment of proton resonances by application of the nuclear Overhauser effect. Nucleic Acids Research. 11: 5717-38. PMID 6193486 DOI: 10.1093/nar/11.16.5717  0.834
1983 Doornbos J, Wreesmann CT, Van Boom JH, Altona C. Conformational analysis of the single-stranded ribonucleic acid A-A-C-C. A one-dimensional and two-dimensional proton NMR study at 500 MHz. European Journal of Biochemistry / Febs. 131: 571-9. PMID 6188609 DOI: 10.1111/J.1432-1033.1983.Tb07301.X  0.585
1983 Marugg J, McLaughlin L, Piel N, Tromp M, van der Marel G, van Boom J. Polymer supported dna synthesis using hydroxybenzotriazole activated phosphotriester intermediates Tetrahedron Letters. 24: 3989-3992. DOI: 10.1016/S0040-4039(00)88244-1  0.421
1982 van der Marel GA, van Boeckel CA, Wille G, van Boom JH. A general method for the synthesis of 5'-monophosphates of DNA fragments via phosphotriester intermediates. Nucleic Acids Research. 10: 2337-51. PMID 7088712 DOI: 10.1093/NAR/10.7.2337  0.452
1982 Alma NC, Harmsen BJ, van Boom JH, van der Marel G, Hilbers CW. 1H NMR studies of the binding of bacteriophage-M13-encoded gene-5 protein to oligo(deoxyadenylic acid)s of varying length. European Journal of Biochemistry. 122: 319-26. PMID 6977447 DOI: 10.1111/J.1432-1033.1982.TB05883.X  0.63
1982 Wang AH, Fujii S, van Boom JH, Rich A. Molecular structure of the octamer d(G-G-C-C-G-G-C-C): modified A-DNA Proceedings of the National Academy of Sciences of the United States of America. 79: 3968-3972. PMID 6955784 DOI: 10.1073/PNAS.79.13.3968  0.569
1982 Wang AH, Fujii S, van Boom JH, van der Marel GA, van Boeckel SA, Rich A. Molecular structure of r(GCG)d(TATACGC): a DNA--RNA hybrid helix joined to double helical DNA. Nature. 299: 601-4. PMID 6181416 DOI: 10.1038/299601a0  0.819
1981 Wang AJ, Quigley GJ, Kolpak FJ, van der Marel G, van Boom JH, Rich A. Left-handed double helical DNA: variations in the backbone conformation. Science (New York, N.Y.). 211: 171-6. PMID 7444458 DOI: 10.1126/SCIENCE.7444458  0.629
1981 Zuiderweg ER, Scheek RM, Veeneman G, van Boom JH, Kaptein R, Rüterjans H, Beyreuther K. 1H NMR studies of lac-operator DNA fragments. Nucleic Acids Research. 9: 6553-69. PMID 7322923 DOI: 10.1093/Nar/9.23.6553  0.303
1981 Mellema JR, Haasnoot CA, Van Boom JH, Altona C. Complete assignment and conformational analysis of a deoxyribotetranucleotide. d(TAAT). A 360 and 500 Mhz NMR study. Biochimica Et Biophysica Acta. 655: 256-64. PMID 7284386 DOI: 10.1016/0005-2787(81)90016-2  0.814
1981 Doornbos J, den Hartog JA, van Boom JH, Altona C. Conformational analysis of the nucleotides A2'-5'A, A2'-5'A2'-5'A and A2'-5'U from nuclear magnetic resonance and circular dichroism studies. European Journal of Biochemistry / Febs. 116: 403-12. PMID 7250133 DOI: 10.1111/J.1432-1033.1981.Tb05349.X  0.487
1981 Olsthoorn CS, Bostelaar LJ, De Rooij JF, Van Boom JH, Altona C. Circular dichroism study of stacking properties of oligodeoxyadenylates and polydeoxyadenylate. A three-state conformational model. European Journal of Biochemistry / Febs. 115: 309-21. PMID 7238508 DOI: 10.1111/j.1432-1033.1981.tb05240.x  0.584
1981 Alma NCM, Harmsen BJM, Hull WE, Van Der Marel G, Van Boom JH, Hilbers CW. Double-resonance experiments at 500 MHz on gene-5 protein and its complex with octadeoxyriboadenylic acid Biochemistry. 20: 4419-4428. PMID 6974567 DOI: 10.1021/BI00518A029  0.67
1981 Quigley GJ, Wang AH, Ughetto G, van der Marel G, van Boom JH, Rich A. Molecular structure of an anticancer drug-DNA complex: daunomycin plus d(CpGpTpApCpG). Proceedings of the National Academy of Sciences of the United States of America. 77: 7204-8. PMID 6938965 DOI: 10.1073/PNAS.77.12.7204  0.654
1981 Alma NCM, Harmsen BJM, Hilbers CW, Van der Marel G, Van Boom JH. 500 MHz 1H NMR study of the role of lysines and arginines in the binding of gene-5 protein to oligoadenylic acids Febs Letters. 135: 15-20. PMID 6797840 DOI: 10.1016/0014-5793(81)80934-9  0.588
1981 Hartel AJ, Wille-Hazeleger G, van Boom JH, Altona C. Conformational analysis of a modified ribotetranucleoside triphosphate: m6(2)A-U-m6(2)A-U studied in aqueous solution by nuclear magnetic resonance at 500 MHz. Nucleic Acids Research. 9: 1405-23. PMID 6785726 DOI: 10.1093/nar/9.6.1405  0.548
1981 Baas PD, Teertstra WR, van Mansfeld AD, Jansz HS, van der Marel GA, Veeneman GH, van Boom JH. Construction of viable and lethal mutations in the origin of bacteriophage 'phi' X174 using synthetic oligodeoxyribonucleotides. Journal of Molecular Biology. 152: 615-39. PMID 6460870 DOI: 10.1016/0022-2836(81)90120-0  0.499
1980 Haasnoot CA, den Hartog JH, de Rooij JF, van Boom JH, Altona C. Loopstructures in synthetic oligodeoxynucleotides. Nucleic Acids Research. 8: 169-81. PMID 7355127 DOI: 10.1093/nar/8.1.169  0.81
1980 Geerdes HA, Van Boom JH, Hilbers CW. Codon-anticodon interaction in tRNAPhe. II. A nuclear magnetic resonance study of the binding of the codon UUC Journal of Molecular Biology. 142: 219-230. PMID 7003160 DOI: 10.1016/0022-2836(80)90046-7  0.461
1980 Backendorf C, Overbeek GP, Van Boom JH, Van Der Marel G, Veeneman G, Van Duin J. Role of 16-S RNA in ribosome messenger recognition European Journal of Biochemistry. 110: 599-604. PMID 7002555  0.428
1980 Olsthoorn CS, Bostelaar LJ, Van Boom JH, Altona C. Conformational characteristics of the trinucleoside diphosphate dApdApdA and its constituents from nuclear magnetic resonance and circular dichroism studies. Extrapolation to the stacked conformers. European Journal of Biochemistry / Febs. 112: 95-110. PMID 6935052 DOI: 10.1111/J.1432-1033.1980.Tb04991.X  0.609
1980 Crawford JL, Kolpak FJ, Wang AH, Quigley GJ, van Boom JH, van der Marel G, Rich A. The tetramer d(CpGpCpG) crystallizes as a left-handed double helix. Proceedings of the National Academy of Sciences of the United States of America. 77: 4016-20. PMID 6933447 DOI: 10.1073/PNAS.77.7.4016  0.595
1980 Geerdes HA, Van Boom JH, Hilbers CW. Nuclear magnetic resonance studies of codon-anticodon interaction in tRNAPhe. I. Effect of binding complementary tetra and pentanucleotides to the anticodon Journal of Molecular Biology. 142: 195-217. PMID 6160254 DOI: 10.1016/0022-2836(80)90045-5  0.465
1980 Baas PD, van Teeffelen HA, Teertstra WR, Jansz HS, Veeneman GH, van der Marel GA, van Boom JH. Restoration of the biological activity of in vitro synthesized phi X DNA by transfection of ung- spheroplasts or dUTPase treatment. Febs Letters. 110: 15-20. PMID 6101560 DOI: 10.1016/0014-5793(80)80012-3  0.432
1978 Geerdes HAM, Van Boom JH, Hilbers CW. Codon-anticodon interaction in Yeast tRNAPhe an 1H NMR study Febs Letters. 88: 27-32. PMID 346374 DOI: 10.1016/0014-5793(78)80599-7  0.495
1977 van Boom JH, Burgers PM, Haasnoot CA. Synthesis of 3'-phosphates of diribonucleoside monophosphates via phosphotriester intermediates. Nucleic Acids Research. 3: 2731-47. PMID 995650 DOI: 10.1093/nar/3.10.2731  0.766
1977 De Leeuw HP, De Jager JR, Koeners HJ, Van Boom JH, Altona C. Puromycin and some of its analogues: conformational properties in solution. A 360-MHz nuclear-magnetic-resonance investigation. European Journal of Biochemistry / Febs. 76: 209-17. PMID 880948 DOI: 10.1111/J.1432-1033.1977.Tb11586.X  0.582
1977 van Boom JH, Burgers PM, van der Marel G, Verdegaal CH, Wille G. Synthesis of oligonucleotides with sequences identical with or analogous to the 3'-end of 16S ribosomal RNA of Escherichia coli: preparation of A-C-C-U-C-C via the modified phosphotriester method. Nucleic Acids Research. 4: 1047-63. PMID 325524 DOI: 10.1093/NAR/4.4.1047  0.428
1976 Altona C, Van Boom JH, Haasnoot CA. Conformational analysis of a DNA triplet in aqueous solution. Thymidylyl-(3'-5')-thymidylyl-(3'-5')-2'-deoxyadenosine, d(T-T-A), studied by 1H nuclear magnetic resonance at 360 MHz. European Journal of Biochemistry / Febs. 71: 557-62. PMID 1009965 DOI: 10.1111/J.1432-1033.1976.Tb11145.X  0.824
Low-probability matches (unlikely to be authored by this person)
1987 Boelens R, Scheek RM, van Boom JH, Kaptein R. Complex of lac repressor headpiece with a 14 base-pair lac operator fragment studied by two-dimensional nuclear magnetic resonance. Journal of Molecular Biology. 193: 213-6. PMID 3586020 DOI: 10.1016/0022-2836(87)90638-3  0.289
1983 Osinga KA, Van der Bliek AM, Van der Horst G, Groot Koerkamp MJ, Tabak HF, Veeneman GH, Van Boom JH. In vitro site-directed mutagenesis with synthetic DNA oligonucleotides yields unexpected deletions and insertions at high frequency. Nucleic Acids Research. 11: 8595-608. PMID 6324090 DOI: 10.1093/NAR/11.24.8595  0.277
1993 Chuprina VP, Rullmann JA, Lamerichs RM, van Boom JH, Boelens R, Kaptein R. Structure of the complex of lac repressor headpiece and an 11 base-pair half-operator determined by nuclear magnetic resonance spectroscopy and restrained molecular dynamics. Journal of Molecular Biology. 234: 446-62. PMID 8230225 DOI: 10.1006/Jmbi.1993.1598  0.273
1991 Struik AF, Zuiderwijk CT, van Boom JH, Elding LI, Reedijk J. Guanine-06 methylation reduces the reactivity of d(GpG) towards platinum complexes. Journal of Inorganic Biochemistry. 44: 249-60. PMID 1765785 DOI: 10.1016/0162-0134(91)84030-D  0.272
1999 De Kort M, Ebrahimi E, Wijsman ER, Van Der Marel GA, Van Boom JH. Synthesis of oligodeoxynucleotides containing 5-(β-D- glucopyranosyloxymethyl)-2'-deoxyuridine, a modified nucleoside in the DNA of Trypanosoma brucei European Journal of Organic Chemistry. 2337-2344.  0.271
1984 van Mansfeld AD, van Teeffelen HA, Baas PD, Veeneman GH, van Boom JH, Jansz HS. The bond in the bacteriophage phi X174 gene A protein--DNA complex is a tyrosyl-5'-phosphate ester. Febs Letters. 173: 351-6. PMID 6235129 DOI: 10.1016/0014-5793(84)80804-2  0.268
1999 Verheijen JC, Van Roon AMM, Van Der Laan AC, Van Der Marel GA, Van Boom JH. Synthesis of DNA-(3')-PNA chimeras with conformationally restricted linkers based on 4-hydroxyproline Nucleosides and Nucleotides. 18: 493-508.  0.267
2000 Paul AV, Mugavero J, Yin J, Hobson S, Schultz S, van Boom JH, Wimmer E. Studies on the attenuation phenotype of polio vaccines: poliovirus RNA polymerase derived from Sabin type 1 sequence is temperature sensitive in the uridylylation of VPg. Virology. 272: 72-84. PMID 10873750 DOI: 10.1006/Viro.2000.0354  0.262
1981 Heidekamp F, Baas PD, van Boom JH, Veeneman GH, Zipursky SL, Jansz HS. Construction and characterization of recombinant plasmid DNAs containing sequences of the origin of bacteriophage phi X174 DNA replication. Nucleic Acids Research. 9: 3335-54. PMID 6269080 DOI: 10.1093/nar/9.14.3335  0.25
1984 Fluit AC, Baas PD, Jansz HS, Veeneman GH, van Boom JH. Gene A protein interacting with recombinant plasmid DNAs containing 25-30 b.p. of the phi X174 replication origin. Advances in Experimental Medicine and Biology. 179: 231-40. PMID 6240924  0.25
2001 Malchère C, Verheijen J, van der Laan S, Bastide L, van Boom J, Lebleu B, Robbins I. A short phosphodiester window is sufficient to direct RNase H-dependent RNA cleavage by antisense peptide nucleic acid. Antisense & Nucleic Acid Drug Development. 10: 463-8. PMID 11198930 DOI: 10.1089/OLI.1.2000.10.463  0.249
1984 Holak TA, Borer PN, Levy GC, van Boom JH, Wang AH. 31P-NMR analysis of the B to Z transition in double-stranded (dC-dG)3 and (dC-dG)4 in high salt solution. Nucleic Acids Research. 12: 4625-35. PMID 6547530 DOI: 10.1093/Nar/12.11.4625  0.244
1980 van Mansfeld AD, Langeveld SA, Baas PD, Jansz HS, van der Marel GA, Veeneman GH, van Boom JH. Recognition sequence of bacteriophage phi X174 gene A protein--an initiator of DNA replication. Nature. 288: 561-6. PMID 6255338 DOI: 10.1038/288561A0  0.242
1997 Vinayak R, Van der Laan AC, Brill R, Otteson K, Andrus A, Kuyl-Yeheskiely E, Van Boom JH. Automated chemical synthesis of PNA and PNA-DNA chimera on a nucleic acid synthesizer Nucleosides and Nucleotides. 16: 1653-1656.  0.241
1990 Klein JC, Bleeker MJ, Lutgerink JT, van Dijk WJ, Brugghe HF, van den Elst H, van der Marel GA, van Boom JH, Westra JG, Berns AJ. Use of shuttle vectors to study the molecular processing of defined carcinogen-induced DNA damage: mutagenicity of single O4-ethylthymine adducts in HeLa cells. Nucleic Acids Research. 18: 4131-7. PMID 2377457 DOI: 10.1093/nar/18.14.4131  0.24
1984 Scheek RM, Boelens R, Russo N, van Boom JH, Kaptein R. Sequential resonance assignments in 1H NMR spectra of oligonucleotides by two-dimensional NMR spectroscopy. Biochemistry. 23: 1371-6. PMID 6722097 DOI: 10.1021/Bi00302A006  0.239
2000 Rieder E, Paul AV, Kim DW, van Boom JH, Wimmer E. Genetic and biochemical studies of poliovirus cis-acting replication element cre in relation to VPg uridylylation. Journal of Virology. 74: 10371-80. PMID 11044081 DOI: 10.1128/Jvi.74.22.10371-10380.2000  0.237
1984 Borer PN, Zanatta N, Holak TA, Levy GC, van Boom JH, Wang AH. Conformation and dynamics of short DNA duplexes: (dC-dG)3 and (dC-dG)4. Journal of Biomolecular Structure & Dynamics. 1: 1373-86. PMID 6400826 DOI: 10.1080/07391102.1984.10507526  0.232
1983 van Wezenbeek P, Vos P, van Boom J, van Kammen A. Molecular cloning and characterization of a complete DNA copy of potato spindle tuber viroid RNA. Nucleic Acids Research. 10: 7947-57. PMID 6897677 DOI: 10.1093/NAR/10.24.7947  0.231
2001 Iwata Y, de Kort M, Challiss RA, van der Marel GA, van Boom JH, Miyamoto S. Conformational analysis of cyclophostin and designed analogs in comparison with the potent IP3 receptor agonist adenophostin A. Drug Design and Discovery. 17: 253-63. PMID 11469755  0.227
1991 Winkler FK, D'Arcy A, Blöcker H, Frank R, van Boom JH. Crystallization of complexes of EcoRV endonuclease with cognate and non-cognate DNA fragments. Journal of Molecular Biology. 217: 235-8. PMID 1992160 DOI: 10.1016/0022-2836(91)90536-F  0.224
1984 Fluit AC, Baas PD, Van Boom JH, Veeneman GH, Jansz HS. Gene A protein cleavage of recombinant plasmids containing the phi X174 replication origin. Nucleic Acids Research. 12: 6443-54. PMID 6236428  0.223
1988 Boelens R, Lamerichs RM, Rullmann JA, van Boom JH, Kaptein R. The interaction of lac repressor headpiece with its operator: an NMR view. Protein Sequences & Data Analysis. 1: 487-98. PMID 3064080  0.223
2002 Jones C, Aguilera B, van Boom JH, Buchanan JG. Confirmation of the D configuration of the 2-substituted arabinitol 1-phosphate residue in the capsular polysaccharide from Streptococcus pneumoniae Type 17F. Carbohydrate Research. 337: 2353-8. PMID 12433501  0.222
1982 Tabak HF, van der Laan J, Osinga KA, Schouten JP, van Boom JH, Veeneman GH. Use of a synthetic DNA oligonucleotide to probe the precision of RNA splicing in a yeast mitochondrial petite mutant. Nucleic Acids Research. 9: 4475-83. PMID 7029466 DOI: 10.1093/NAR/9.18.4475  0.22
1983 Scheek RM, Zuiderweg ER, Klappe KJ, van Boom JH, Kaptein R, Rüterjans H, Beyreuther K. lac Repressor headpiece binds specifically to half of the lac operator: a proton nuclear magnetic resonance study. Biochemistry. 22: 228-35. PMID 6338916 DOI: 10.1021/Bi00270A033  0.22
1997 Gao Y, Robinson H, Wijsman ER, Van Der Marel GA, Van Boom JH, Wang AHJ. Binding of daunorubicin to β-D-glucosylated DNA found in protozoa Tryponosoma brucei studied by X-ray crystallography Journal of the American Chemical Society. 119: 1496-1497. DOI: 10.1021/ja963793r  0.217
1994 De Ruiter GA, Van Bruggen-Van der Lugt AW, Mischnick P, Smid P, Van Boom JH, Notermans SH, Rombouts FM. 2-O-methyl-D-mannose residues are immunodominant in extracellular polysaccharides of Mucor racemosus and related molds. The Journal of Biological Chemistry. 269: 4299-306. PMID 8307996  0.213
1991 Kellenbach E, Härd T, Boelens R, Dahlman K, Carlstedt-Duke J, Gustafsson JA, van der Marel GA, van Boom JH, Maler B, Yamamoto KR. Photo-CIDNP study of the interaction between the glucocorticoid receptor DNA-binding domain and glucocorticoid response elements. Journal of Biomolecular Nmr. 1: 105-10. PMID 1841686 DOI: 10.1007/Bf01874574  0.213
1982 Rietveld K, van Poelgeest R, Pleij CWA, van Boom JH, Bosch L. The tRNA-Uke structure at the 3′ terminus of turnip yellow mosaic virus RNA. Differences and similarities with canonical tRNA Nucleic Acids Research. 10: 1929-1946. DOI: 10.1093/Nar/10.6.1929  0.212
1983 Kallenbach NR, Ma RI, Wand AJ, Veeneman GH, van Boom JH, Seeman NC. Fourth rank immobile nucleic acid junctions. Journal of Biomolecular Structure & Dynamics. 1: 159-68. PMID 6401109 DOI: 10.1080/07391102.1983.10507432  0.212
2004 Ijsselstijn M, Aguilera B, Van Der Marel GA, Van Boom JH, Van Delft FL, Schoemaker HE, Overkleeft HS, Rutjes FPJT, Overhand M. Ring-closing alkyne metathesis mediated synthesis of cyclic β-turn mimetics Tetrahedron Letters. 45: 4379-4382. DOI: 10.1016/J.Tetlet.2004.03.181  0.211
1997 Buijsman RC, Schipperijn JWJ, Kuyl-Yeheskiely E, Van Der Marel GA, Van Boeckel CAA, Van Boom JH. Design and synthesis of a possible mimic of a thrombin-binding DNA aptamer Bioorganic and Medicinal Chemistry Letters. 7: 2027-2032. DOI: 10.1016/S0960-894X(97)00351-X  0.211
2003 Paul AV, Peters J, Mugavero J, Yin J, van Boom JH, Wimmer E. Biochemical and genetic studies of the VPg uridylylation reaction catalyzed by the RNA polymerase of poliovirus. Journal of Virology. 77: 891-904. PMID 12502805 DOI: 10.1128/Jvi.77.2.891-904.2003  0.21
1997 Van Der Laan AC, Brill R, Kuimelis RG, Kuyl-Yeheskiely E, Van Boom JH, Andrus A, Vinayak R. A convenient automated solid-phase synthesis of PNA-(5')-DNA-(3')-PNA chimera Tetrahedron Letters. 38: 2249-2252. DOI: 10.1016/S0040-4039(97)00344-4  0.206
2003 Luca S, White JF, Sohal AK, Filippov DV, van Boom JH, Grisshammer R, Baldus M. The conformation of neurotensin bound to its G protein-coupled receptor. Proceedings of the National Academy of Sciences of the United States of America. 100: 10706-11. PMID 12960362 DOI: 10.1073/Pnas.1834523100  0.202
1980 De Rooij JF, Bloemhoff W, Van Boom JH. Automated sequence analysis of a synthetic DNA fragment by anion-exchange high-performance liquid chromatography. Journal of Chromatography. 177: 380-4. PMID 528647 DOI: 10.1016/S0021-9673(01)96339-3  0.202
1999 Monaco V, van de Wetering KI, Meeuwenoord NJ, van den Elst HA, Stuivenberg HR, Visse R, van der Kaaden JC, Moolenaar GF, Verhoeven EE, Goosen N, van der Marel GA, van Boom JH. Synthesis and biological evaluation of modified DNA fragments for the study of nucleotide excision repair in E. coli. Nucleosides & Nucleotides. 18: 1339-41. PMID 10474222 DOI: 10.1080/07328319908044710  0.201
2001 Ovaa H, Van der Marel GA, Van Boom JH. A convenient approach towards 2′-analogs of zoapatanol from D-glucose Tetrahedron Letters. 42: 5749-5752. DOI: 10.1016/S0040-4039(01)00932-7  0.2
1977 van Boom JH, de Rooy JF. Sequence analysis of synthetic oligonucleotides by high-performance liquid anion-exchange chromatography. Journal of Chromatography. 131: 169-77. PMID 192745 DOI: 10.1016/s0021-9673(00)80930-9  0.193
1992 Klein JC, Bleeker MJ, Saris CP, Roelen HC, Brugghe HF, van den Elst H, van der Marel GA, van Boom JH, Westra JG, Kriek E. Repair and replication of plasmids with site-specific 8-oxodG and 8-AAFdG residues in normal and repair-deficient human cells. Nucleic Acids Research. 20: 4437-43. PMID 1408745  0.191
2002 Van Den Berg RJBHN, Korevaar CGN, Van Der Marel GA, Overkleeft HS, Van Boom JH. A simple and low cost synthesis of D-erythro-sphingosine and D-erythro-azidosphingosine from D-ribo-phytosphingosine: Glycosphingolipid precursors Tetrahedron Letters. 43: 8409-8412. DOI: 10.1016/S0040-4039(02)01807-5  0.191
2001 van Hooft PA, Litjens RE, van der Marel GA, van Boeckel CA, van Boom JH. Stereoselective transformations on D-glucose-derived eight-membered ring carbocycles. Organic Letters. 3: 731-3. PMID 11259048 DOI: 10.1021/ol007047+  0.19
2000 Paul AV, Rieder E, Kim DW, van Boom JH, Wimmer E. Identification of an RNA hairpin in poliovirus RNA that serves as the primary template in the in vitro uridylylation of VPg. Journal of Virology. 74: 10359-70. PMID 11044080 DOI: 10.1128/Jvi.74.22.10359-10370.2000  0.19
2004 Grotenbreg GM, Tuin AW, Witte MD, Leeuwenburgh MA, Van Boom JH, Van Der Marel GA, Overkleeft HS, Overhand M. An expeditious route towards pyranopyran sugar amino acids Synlett. 904-906. DOI: 10.1055/S-2004-820021  0.187
1984 Hensgens LA, Brakenhoff J, De Vries BF, Sloof P, Tromp MC, Van Boom JH, Benne R. The sequence of the gene for cytochrome c oxidase subunit I, a frameshift containing gene for cytochrome c oxidase subunit II and seven unassigned reading frames in Trypanosoma brucei mitochondrial maxi-circle DNA. Nucleic Acids Research. 12: 7327-44. PMID 6093040 DOI: 10.1093/NAR/12.19.7327  0.185
1989 De Bont HBA, Liskamp RMJ, O'Brian CA, Erkelens C, Veeneman GH, Van Boom JH. Synthesis of a substrate of protein kinase C and its corresponding phosphopeptide International Journal of Peptide and Protein Research. 33: 115-123. PMID 2707968 DOI: 10.1111/J.1399-3011.1989.Tb00196.X  0.185
1982 van Mansfeld AD, van Teeffelen HA, Zandberg J, Baas PD, Jansz HS, Veeneman GH, van Boom JH. A protein of bacteriophage phi X174 carries an oligonucleotide which it can transfer to the 3' -OH of a DNA chain. Febs Letters. 150: 103-8. PMID 6218997 DOI: 10.1016/0014-5793(82)81313-6  0.184
1981 Backendorf C, Ravensbergen CJ, Van der Plas J, van Boom JH, Veeneman G, Van Duin J. Basepairing potential of the 3' terminus of 16S RNA: dependence on the functional state of the 30S subunit and the presence of protein S21. Nucleic Acids Research. 9: 1425-44. PMID 7232220 DOI: 10.1093/NAR/9.6.1425  0.183
1992 van der Klein-de Gunst FJ, van Boom JH, Liskamp RM. Computer-aided molecular modeling and design of DNA-inserting molecules. Journal of Computer-Aided Molecular Design. 6: 33-46. PMID 1583538 DOI: 10.1007/Bf00124385  0.182
1993 Kuijpers WH, Kuyl-Yeheskiely E, van Boom JH, van Boeckel CA. The application of the AMB protective group in the solid-phase synthesis of methylphosphonate DNA analogues. Nucleic Acids Research. 21: 3493-500. PMID 8346028  0.18
1996 Zegelaar-Jaarsveld K, Van Der Plas SC, Van Der Marel GA, Van Boom JH. Preparation of disaccharide haptens corresponding to Salmonella serogroups B and D Journal of Carbohydrate Chemistry. 15: 665-689.  0.179
1999 Ovaa H, Codée JDC, Lastdrager B, Overkleeft HS, Van Der Marel GA, Van Boom JH. A versatile approach to the synthesis of highly functionalised carbocycles Tetrahedron Letters. 40: 5063-5066. DOI: 10.1016/S0040-4039(99)00911-9  0.178
1992 van der Klein PA, van Boom JH. Application of cyclic sulfates in the synthesis of 6-deoxy-D-manno-heptopyranose derivatives. Carbohydrate Research. 224: 193-200. PMID 1591761  0.175
1983 Cornelissen BJ, Brederode FT, Veeneman GH, van Boom JH, Bol JF. Complete nucleotide sequence of alfalfa mosaic virus RNA 2. Nucleic Acids Research. 11: 3019-25. PMID 6304618 DOI: 10.1093/Nar/11.10.3019  0.171
2003 Turner JJ, Meeuwenoord NJ, Rood A, Borst P, Van der Marel GA, Van Boom JH. Reinvestigation into the synthesis of oligonucleotides containing 5-(β-D-glucopyranosyloxymethyl)-2′-deoxyuridine European Journal of Organic Chemistry. 3832-3839.  0.17
2002 De Koning MC, Filippov DV, Meeuwenoord N, Overhand M, Van Der Marel GA, Van Boom JH. An approach to the synthesis of peptide-PNA-peptide conjugates via native ligation Tetrahedron Letters. 43: 8173-8176. DOI: 10.1016/S0040-4039(02)01856-7  0.167
2003 Kriek NMAJ, Van der Hout E, Kelly P, Van Meijgaarden KE, Geluk A, Ottenhoff THM, Van der Marel GA, Overhand M, Van Boom JH, Valentijn ARPM, Overkleeft HS. Synthesis of novel tetrahydropyran-based dipeptide isosters by overman rearrangement of 2,3-didehydroglycosides European Journal of Organic Chemistry. 2418-2427. DOI: 10.1002/Ejoc.200200710  0.166
2001 Luca S, Filippov DV, van Boom JH, Oschkinat H, de Groot HJ, Baldus M. Secondary chemical shifts in immobilized peptides and proteins: a qualitative basis for structure refinement under magic angle spinning. Journal of Biomolecular Nmr. 20: 325-31. PMID 11563556 DOI: 10.1023/A:1011278317489  0.165
1999 Kamst E, Zegelaar-Jaarsveld K, Van Der Marel GA, Van Boom JH, Lugtenberg BJJ, Spaink HP. Chemical synthesis of N-acetylglucosamine derivatives and their use as glycosyl acceptors by the Mesorhizobium loti chitin oligosaccharide synthase NodC Carbohydrate Research. 321: 176-189. DOI: 10.1016/S0008-6215(99)00190-1  0.159
1996 Van Der Laan AC, Strömberg R, Van Boom JH, Kuyl-Yeheskiely E, Efimov VA, Chakhmakhcheva OG. An approach towards the synthesis of oligomers containing a N-2-hydroxyethyl-aminomethylphosphonate backbone: A novel PNA analogues Tetrahedron Letters. 37: 7857-7860. DOI: 10.1016/0040-4039(96)01750-9  0.159
1986 Nielsen J, Taagaard M, Marugg JE, van Boom JH, Dahl O. Application of 2-cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite for in situ preparation of deoxyribonucleoside phosphoramidites and their use in polymer-supported synthesis of oligodeoxyribonucleotides. Nucleic Acids Research. 14: 7391-403. PMID 3763407 DOI: 10.1093/Nar/14.18.7391  0.155
1999 McCormick J, Li Y, McCormick K, Duynstee HI, Van Engen AK, Van Der Marel GA, Ganem B, Van Boom JH, Meinwald J. Structure and total synthesis of HF-7, a neuroactive glyconucleoside disulfate from the funnel-web spider Hololena curta Journal of the American Chemical Society. 121: 5661-5665. DOI: 10.1021/Ja990274Q  0.154
2004 Turner JJ, Sikkema FD, Erkelens K, Van Der Marel GA, Overkleeft HS, Van Boom JH, Overhand M. Novel reversed chain modified oligopeptides via sequential α-N-mitsunobu condensation of a functionalized C-glycoside Chemistry Letters. 33: 468-469. DOI: 10.1246/Cl.2004.468  0.153
1982 den Hartog JA, Wille G, Scheublin RA, van Boom JH. Chemical synthesis of a messenger ribonucleic acid fragment: AUGUUCUUCUUCUUCUUC. Biochemistry. 21: 1009-18. PMID 7074044 DOI: 10.1021/BI00534A028  0.151
1998 Gee JE, Robbins I, van der Laan AC, van Boom JH, Colombier C, Leng M, Raible AM, Nelson JS, Lebleu B. Assessment of high-affinity hybridization, RNase H cleavage, and covalent linkage in translation arrest by antisense oligonucleotides. Antisense & Nucleic Acid Drug Development. 8: 103-11. PMID 9593048  0.147
2000 Van Well RM, Overkleeft HS, Overhand M, Carstenen EV, Van der Marel GA, Van Boom JH. Parallel synthesis of cyclic sugar amino acid/amino acid hybrid molecules Tetrahedron Letters. 41: 9331-9335. DOI: 10.1016/S0040-4039(00)01693-2  0.147
1992 Van Bruggen-Van Der Lugt AW, Kamphuis HJ, De Ruiter GA, Mischnick P, Van Boom JH, Rombouts FM. New structural features of the antigenic extracellular polysaccharides of Penicillium and Aspergillus species revealed with exo-beta-D-galactofuranosidase. Journal of Bacteriology. 174: 6096-102. PMID 1383191  0.146
1981 Koper-Zwarthoff EC, Brederode FT, Veeneman G, van Boom JH, Bol JF. Nucleotide sequences at the 5'-termini of the alfalfa mosaic virus RNAs and the intercistronic junction in RNA 3. Nucleic Acids Research. 8: 5635-47. PMID 6927843 DOI: 10.1093/Nar/8.23.5635  0.145
2001 Litjens REJN, Leeuwenburgh MA, Van Der Marel GA, Van Boom JH. A novel approach towards the stereoselective synthesis of 2-azido-2-deoxy-β-D-mannosides Tetrahedron Letters. 42: 8693-8696. DOI: 10.1016/S0040-4039(01)01880-9  0.144
1998 Duynstee HI, De Koning MC, Van Der Marel GA, Van Boom JH. Synthesis of 3,4,5-trimethoxyphenyl 5-O-caffeoyl-β-D-erythro- apiofuranosyl-(1→6)-β D-glucopyranoside: Kelampayoside B Tetrahedron Letters. 39: 4129-4132. DOI: 10.1016/S0040-4039(98)00673-X  0.141
2002 Ovaa H, Lastdrager B, Codée JDC, Van der Marel GA, Overkleeft HS, Van Boom JH. Aflexible synthesis of cyclopentitol derivatives based on ring-closing metathesis of carbohydrate-derived 1,6-dienes Journal of the Chemical Society. Perkin Transactions 1. 2370-2377.  0.141
1999 Overkleeft HS, Verhelst SHL, Pieterman E, Meeuwenoord NJ, Overhand M, Cohen LH, Van Der Marel GA, Van Boom JH. Design and synthesis of a protein:farnesyltransferase inhibitor based on sugar amino acids Tetrahedron Letters. 40: 4103-4106. DOI: 10.1016/S0040-4039(99)00697-8  0.14
1989 Notermans S, Veeneman GH, van Zuylen CW, Hoogerhout P, van Boom JH. (1----5)-linked beta-D-galactofuranosides are immunodominant in extracellular polysaccharides of Penicillium and Aspergillus species. Molecular Immunology. 25: 975-9. PMID 3216871 DOI: 10.1016/0161-5890(88)90003-X  0.14
1997 Holmes CE, Duff RJ, van der Marel GA, van Boom J, Hecht SM. On the chemistry of RNA degradation by Fe.bleomycin. Bioorganic & Medicinal Chemistry. 5: 1235-48. PMID 9222517 DOI: 10.1016/S0968-0896(97)00038-2  0.138
2001 Timmer MSM, Ovaa H, Filippov DV, Van Der Marel GA, Van Boom JH. Synthesis of phosphorus mono- and bicycles by catalytic ring-closing metathesis Tetrahedron Letters. 42: 8231-8233. DOI: 10.1016/S0040-4039(01)01740-3  0.138
1979 de Rooij JF, Wille-Hazeleger G, Burgers PM, van Boom JH. Neighbouring group participation in the unblocking of phosphotriesters of nucleic acids. Nucleic Acids Research. 6: 2237-59. PMID 461188 DOI: 10.1093/NAR/6.6.2237  0.137
2003 De Koning MC, Filippov DV, Van Der Marel GA, Van Boom JH, Overhand M. Synthesis of macrocyclic peptide nucleic acid derivatives via intramolecular chemical ligation Tetrahedron Letters. 44: 7597-7600. DOI: 10.1016/J.Tetlet.2003.08.061  0.136
1995 Biessen EA, Broxterman H, van Boom JH, van Berkel TJ. The cholesterol derivative of a triantennary galactoside with high affinity for hepatic asialoglycoprotein receptor: a potent cholesterol lowering agent. Journal of Medicinal Chemistry. 38: 1846-52. PMID 7783116  0.136
1997 van Leeuwen F, Wijsman ER, Kieft R, van der Marel GA, van Boom JH, Borst P. Localization of the modified base J in telomeric VSG gene expression sites of Trypanosoma brucei. Genes & Development. 11: 3232-41. PMID 9389654 DOI: 10.1101/Gad.11.23.3232  0.136
1995 Jalink K, Hengeveld T, Mulder S, Postma FR, Simon MF, Chap H, van der Marel GA, van Boom JH, van Blitterswijk WJ, Moolenaar WH. Lysophosphatidic acid-induced Ca2+ mobilization in human A431 cells: structure-activity analysis. The Biochemical Journal. 307: 609-16. PMID 7733903 DOI: 10.1042/Bj3070609  0.136
2003 Van Well RM, Meijer MEA, Overkleeft HS, Van Boom JH, Van Der Marel GA, Overhand M. Synthesis of bridged sugar amino acids: A new entry into conformationally locked δ- and ε-amino acids Tetrahedron. 59: 2423-2434. DOI: 10.1016/S0040-4020(03)00288-6  0.132
2000 Timmer MSM, Ovaa H, Filippov DV, Van der Marel GA, Van Boom JH. An expeditious route to phosphorus heterocycles based on ring-closing metathesis Tetrahedron Letters. 41: 8635-8638.  0.132
1982 Simons GFM, Veeneman GH, Konings RNH, van Boom JH, Schoenmakers JGG. Oligonucleotide-directed mutagenesis of gene IX of bacteriophage M13 Nucleic Acids Research. 10: 821-832. DOI: 10.1093/Nar/10.3.821  0.132
1998 Ovaa H, Codée JDC, Lastdrager B, Overkleeft HS, Van Der Marel GA, Van Boom JH. A stereoselective and efficient route to (3S, 4R, 5S)-(+)-4,5- dihydroxycyclopent-1-en-3-ylamine: The side chain of the hypermodified nucleoside Q Tetrahedron Letters. 39: 7987-7990. DOI: 10.1016/S0040-4039(98)01738-9  0.131
2003 Van Well RM, Overkleeft HS, Van Boom JH, Coop A, Wang JB, Wang H, Van der Marel GA, Overhand M. Synthesis of novel sugar amino acids by Curtius rearrangement European Journal of Organic Chemistry. 1704-1710. DOI: 10.1002/Ejoc.200210682  0.13
1988 Neefjes JJ, Verkerk JM, Broxterman HJ, van der Marel GA, van Boom JH, Ploegh HL. Recycling glycoproteins do not return to the cis-Golgi. The Journal of Cell Biology. 107: 79-87. PMID 2839522 DOI: 10.1083/Jcb.107.1.79  0.13
1995 Biessen EA, Beuting DM, Roelen HC, van de Marel GA, van Boom JH, van Berkel TJ. Synthesis of cluster galactosides with high affinity for the hepatic asialoglycoprotein receptor. Journal of Medicinal Chemistry. 38: 1538-46. PMID 7739012  0.13
1999 Verheijen JC, Bayly SF, Player MR, Torrence PF, van der Marel GA, van Boom JH. 2-5A-PNA complexes: a novel class of antisense compounds. Nucleosides & Nucleotides. 18: 1485-6. PMID 10474229  0.128
1986 Bovenberg RA, Burbach JP, Wiegant VM, Veeneman GH, van Boom JH, Baas PD, Jansz HS, de Wied D. gamma-Endorphin and schizophrenia: amino acid composition of gamma-endorphin and nucleotide sequence of gamma-endorphin cDNA from pituitary glands of schizophrenic patients. Brain Research. 376: 29-37. PMID 2424570 DOI: 10.1016/0006-8993(86)90896-6  0.126
1982 Van der Ploeg LH, Liu AY, Michels PA, De Lange T, Borst P, Majumder HK, Weber H, Veeneman GH, Van Boom J. RNA splicing is required to make the messenger RNA for a variant surface antigen in trypanosomes. Nucleic Acids Research. 10: 3591-604. PMID 6287414 DOI: 10.1093/Nar/10.12.3591  0.126
1990 Cosio EG, Frey T, Verduyn R, van Boom J, Ebel J. High-affinity binding of a synthetic heptaglucoside and fungal glucan phytoalexin elicitors to soybean membranes. Febs Letters. 271: 223-6. PMID 2226806 DOI: 10.1016/0014-5793(90)80411-B  0.126
2001 Aguilera B, Siegal G, Overkleeft HS, Meeuwenoord NJ, Rutjes FPJT, Van Hest JCM, Schoemaker HE, Van Der Marel GA, Van Boom JH, Overhand M. Synthesis and structural analysis of a β-hairpin peptide containing a sugar amino acid European Journal of Organic Chemistry. 1541-1547. DOI: 10.1002/1099-0690(200104)2001:8<1541::Aid-Ejoc1541>3.0.Co;2-7  0.125
1998 Paul AV, van Boom JH, Filippov D, Wimmer E. Protein-primed RNA synthesis by purified poliovirus RNA polymerase. Nature. 393: 280-4. PMID 9607767 DOI: 10.1038/30529  0.125
1973 van Boom JH, de Rooy JF, Reese CB. The synthesis of oligoribonucleotides. X. Preparation of 2',3'-cyclic phosphates of ribonucleosides and diribonucleoside phosphates via phosphotriester intermediates. Journal of the Chemical Society. Perkin Transactions 1. 21: 2513-7. PMID 4797713 DOI: 10.1039/P19730002513  0.124
1994 Klein JC, Bleeker MJ, Roelen HC, Rafferty JA, Margison GP, Brugghe HF, van den Elst H, van der Marel GA, van Boom JH, Kriek E. Role of nucleotide excision repair in processing of O4-alkylthymines in human cells. The Journal of Biological Chemistry. 269: 25521-8. PMID 7929253  0.124
1998 Van der Laan AC, Van Amsterdam I, Tesser GI, Van Boom JH, Kuyl-Yeheskiely E. Synthesis of chirally pure ornithine based PNA analogues Nucleosides and Nucleotides. 17: 219-231.  0.123
1985 Osinga K, Swinkels B, Gibson W, Borst P, Veeneman G, Van Boom J, Michels P, Opperdoes F. Topogenesis of microbody enzymes: a sequence comparison of the genes for the glycosomal (microbody) and cytosolic phosphoglycerate kinases of Trypanosoma brucei. The Embo Journal. 4: 3811-3817. DOI: 10.1002/J.1460-2075.1985.Tb04152.X  0.123
2000 Ovaa H, Stragies R, Van Der Marel GA, Van Boom JH, Blechert S. Asymmetric synthesis of indolizidine alkaloids by ring-closing-ring-opening metathesis Chemical Communications. 1501-1502.  0.123
1999 Cohen LH, Pieterman E, van Leeuwen RE, Du J, Negre-Aminou P, Valentijn AR, Overhand M, van der Marel GA, van Boom JH. Inhibition of human smooth muscle cell proliferation in culture by farnesyl pyrophosphate analogues, inhibitors of in vitro protein: farnesyl transferase. Biochemical Pharmacology. 57: 365-73. PMID 9933024 DOI: 10.1016/S0006-2952(98)00322-0  0.122
2002 Burg D, Filippov DV, Hermanns R, van der Marel GA, van Boom JH, Mulder GJ. Peptidomimetic glutathione analogues as novel gammaGT stable GST inhibitors. Bioorganic & Medicinal Chemistry. 10: 195-205. PMID 11738622 DOI: 10.1016/S0968-0896(01)00269-3  0.122
1998 Ovaa H, Leeuwenburgh MA, Overkleeft HS, Van Der Marel GA, Van Boom JH. An expeditious route to the synthesis of highly functionalized chiral oxepines from monosaccharides Tetrahedron Letters. 39: 3025-3028. DOI: 10.1016/S0040-4039(98)00324-4  0.12
2002 Verhelst SHL, Wiedenhof W, Ovaa H, Van Der Marel GA, Overkleeft HS, Van Boeckel CAA, Van Boom JH. A stereoselective route towards highly functionalized 4,6-diaminocyclohexene derivatives Tetrahedron Letters. 43: 6451-6455. DOI: 10.1016/S0040-4039(02)01364-3  0.119
2001 Turner JJ, Filippov DV, Overhand M, Van der Marel GA, Van Boom JH. Synthesis of novel amino acid carbohydrate hybrids via Mitsunobu glycosylation of nitrobenzenesulfonamides Tetrahedron Letters. 42: 5763-5767. DOI: 10.1016/S0040-4039(01)01062-0  0.119
1997 Van Straten NCR, Kriek NMAJ, Cziria ZAC, Van der Marel GA, Van Boom JH. Synthesis of 3',4'-bisphosphate-containing analogs of adenophostin A Tetrahedron. 53: 6539-6554. DOI: 10.1016/S0040-4020(97)00309-8  0.118
1997 Ouwerkerk-Mahadevan S, Tirona RG, Ripping RA, Ploemen JH, van Bladeren PJ, Pang KS, van Boom JH, Mulder GJ. Inhibition of glutathione conjugation by glutathione analogues in the perfused rat liver. Effect of esterification on the potency of gamma-L-glutamyl-alpha-(D-2-aminoadipyl)-N-2-heptylamine. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 25: 1137-43. PMID 9321516  0.118
1997 Leeuwenburgh MA, Timmers CM, Van Der Marel GA, Van Boom JH, Mallet JM, Sinaÿ PG. Stereoselective synthesis of α-C-(alkynyl)-glycosides via ring-opening of α-1,2-anhydrosugars Tetrahedron Letters. 38: 6251-6254. DOI: 10.1016/S0040-4039(97)01381-6  0.117
1998 Timmers CM, Wigchert SCM, Leeuwenburgh MA, Van Der Marel GA, Van Boom JH. Synthesis of tetrameric arabinogalactans based on 1,2-anhydrosugars European Journal of Organic Chemistry. 91-97.  0.115
2002 Ovaa H, Stapper C, Van Der Marel GA, Overkleeft HS, Van Boom JH, Blechert S. Ruthenium catalyzed ring rearrangement: A rapid entry to substituted aza- and oxacycles Tetrahedron. 58: 7503-7518. DOI: 10.1016/S0040-4020(02)00832-3  0.115
1997 Van Straten NCR, Van der Marel GA, Van Boom JH. Synthesis of 2',3',4'-trisphosphate-containing analogs of adenophostin A Tetrahedron. 53: 6523-6538. DOI: 10.1016/S0040-4020(97)00308-6  0.115
1975 Reese CB, Stewart JC, van Boom JH, de Leeuw HP, Nagel J, de Rooy JF. The synthesis of oligoribonucleotides. Part XI. Preparation of ribonucleoside 2'-acetal 3'-esters by selective deacylation. Journal of the Chemical Society. Perkin Transactions 1. 934-42. PMID 1170189 DOI: 10.1039/P19750000934  0.114
1992 Evenberg D, Hoogerhout P, van Boeckel CA, Rijkers GT, Beuvery EC, van Boom JH, Poolman JT. Preparation, antigenicity, and immunogenicity of synthetic ribosylribitol phosphate oligomer-protein conjugates and their potential use for vaccination against Haemophilus influenzae type b disease. The Journal of Infectious Diseases. 165: S152-5. PMID 1588151  0.114
1998 Van Hooft PAV, Leeuwenburgh MA, Overkleeft HS, Van Der Marel GA, Van Boeckel CAA, Van Boom JH. A novel and flexible synthesis of pyranose spiroacetal derivatives Tetrahedron Letters. 39: 6061-6064. DOI: 10.1016/S0040-4039(98)01247-7  0.113
2004 Timmer MSM, Codée JDC, Overkleeft HS, Van Boom JH, Van Der Marel GA. A tandem ring-closing metathesis cleavable linker system for solid-phase oligosaccharide synthesis Synlett. 2155-2158. DOI: 10.1055/s-2004-831301  0.113
1997 Van Strafen NCR, Kriek NMAJ, Timmers CM, Wigchert SCM, Van Der Marel GA, Van Boom JH. Synthesis of a trisaccharide fragment corresponding to the lipopolysaccharide region of vibrio parahaemolyticus Journal of Carbohydrate Chemistry. 16: 947-966.  0.111
2004 van den Berg RJ, Donker-Koopman W, van Boom JH, Aerts HM, Noort D. Design and synthesis of 2-acetamidomethyl derivatives of isofagomine as potential inhibitors of human lysosomal beta-hexosaminidases. Bioorganic & Medicinal Chemistry. 12: 891-902. PMID 14980601 DOI: 10.1016/j.bmc.2003.12.040  0.111
1987 Notermans S, Wieten G, Engel HW, Rombouts FM, Hoogerhout P, van Boom JH. Purification and properties of extracellular polysaccharide (EPS) antigens produced by different mould species. The Journal of Applied Bacteriology. 62: 157-66. PMID 3571038 DOI: 10.1111/J.1365-2672.1987.TB02394.X  0.11
1997 Leeuwenburgh MA, Overkleeft HS, Van Der Marel GA, Van Boom JH. A Novel Approach Towards cis- and trans-Fused Pyranopyrans Based on Ring-Closing Metathesis Reaction of Carbohydrate Derivatives Synlett. 1997: 1263-1264.  0.11
1999 Leeuwenburgh MA, Kulker C, Duynstee HI, Overkleeft HS, Van der Marel GA, Van Boom JH. A convenient route to cis- and trans-fused bicyclic ethers by ruthenium mediated ring-closing metathesis of diene and enyne carbohydrate derivatives Tetrahedron. 55: 8253-8262. DOI: 10.1016/S0040-4020(99)00296-3  0.11
1998 Overhand M, Stuivenberg HR, Pieterman E, Cohen LH, Van Leeuwen REW, Valentijn ARPM, Overkleeft HS, Van Der Marel GA, Van Boom JH. Inhibitors of protein:farnesyl transferase and protein:geranylgeranyl transferase I: Synthesis of homologous diphosphonate analogs of isoprenylated pyrophosphate Bioorganic Chemistry. 26: 269-282. DOI: 10.1006/Bioo.1998.1101  0.11
1992 Peeters CC, Evenberg D, Hoogerhout P, Käyhty H, Saarinen L, van Boeckel CA, van der Marel GA, van Boom JH, Poolman JT. Synthetic trimer and tetramer of 3-beta-D-ribose-(1-1)-D-ribitol-5-phosphate conjugated to protein induce antibody responses to Haemophilus influenzae type b capsular polysaccharide in mice and monkeys. Infection and Immunity. 60: 1826-33. PMID 1563770  0.109
1996 Filippov D, Meeuwenoord NJ, Van Der Marel GA, Efimov VA, Kuyl-Yeheskiely E, Van Boom JH. An Approach to the Solid Phase Synthesis of Oligonucleotides Containing N-Acylphosphoramidate Internucleosidic Linkages Synlett. 1996: 769-771.  0.109
1998 Timmers CM, Van Straten NCR, Van Der Marel GA, Van Boom JH. An expeditious route to Streptococci and Enterococci glycolipids via ring-opening of 1,2-anhydrosugars with protic acids Journal of Carbohydrate Chemistry. 17: 471-487.  0.108
2003 Robillard MS, Leith JS, Van der Marel GA, Van Boom JH, Reedijk J. Application of gel-phase 195Pt NMR spectroscopy in a novel solid-phase synthesis of a primary amine dichloroplatinum(II) complex European Journal of Inorganic Chemistry. 1529-1532.  0.107
2000 Leeuwenburgh MA, Appeldoorn CCM, Van Hooft PAV, Overkleeft HS, Van Der Marel GA, Van Boom JH. Synthesis of highly functionalised carbohydrate-derived spiroacetals by ring-closing metathesis and Pauson-Khand reaction of ketoglycosidic enynes European Journal of Organic Chemistry. 873-877.  0.107
1997 Van Delft FL, Timmers CM, Van Der Marel GA, Van Boom JH. Preparation of 2-oxazolidinones by intramolecular nucleophilic substitution Synthesis. 450-454.  0.107
1987 Baas PD, Liewerink H, van Teeffelen HA, van Mansfeld AD, van Boom JH, Jansz HS. Alteration of the ATG start codon of the A protein of bacteriophage phi X174 into an ATT codon yields a viable phage indicating that A protein is not essential for phi X174 reproduction. Febs Letters. 218: 119-25. PMID 2954853 DOI: 10.1016/0014-5793(87)81030-X  0.104
2000 Cohen LH, Pieterman E, van Leeuwen RE, Overhand M, Burm BE, van der Marel GA, van Boom JH. Inhibitors of prenylation of Ras and other G-proteins and their application as therapeutics. Biochemical Pharmacology. 60: 1061-8. PMID 11007942 DOI: 10.1016/S0006-2952(00)00386-5  0.101
2005 Robillard MS, Van Alphen S, Meeuwenoord NJ, Jansen BAJ, Van Der Marel GA, Van Boom JH, Reedijk J. Solid-phase synthesis of peptide-platinum complexes using platinum-chelating building blocks derived from amino acids New Journal of Chemistry. 29: 220-225. DOI: 10.1039/B411219A  0.1
1987 Voskuilen M, Vermond A, Veeneman GH, van Boom JH, Klasen EA, Zegers ND, Nieuwenhuizen W. Fibrinogen lysine residue A alpha 157 plays a crucial role in the fibrin-induced acceleration of plasminogen activation, catalyzed by tissue-type plasminogen activator Journal of Biological Chemistry. 262: 5944-5946. PMID 3106345  0.099
2002 El Oualid F, Bruining L, Leroy IM, Cohen LH, Van Boom JH, Van Der Marel GA, Overkleeft HS, Overhand M. Synthesis and biological evaluation of protein:geranylgeranyltransferase I inhibitors based on the CaaX box: Incorporation of sugar amino acids as dipeptide isosters Helvetica Chimica Acta. 85: 3455-3472. DOI: 10.1002/1522-2675(200210)85:10<3455::Aid-Hlca3455>3.0.Co;2-#  0.099
1991 Noort D, Meijer EA, Visser TJ, Meerman JH, Van der Marel GA, Van Boom JH, Mulder GJ. Selective inhibition of glucuronidation by 2,2,2-triphenylethyl-UDP in isolated rat hepatocytes: conjugation of harmol, 3,3',5-triiodothyronine, and N-hydroxy-2-acetylaminofluorene. Molecular Pharmacology. 40: 316-20. PMID 1908549  0.099
1996 Sakairi N, Basten JEM, Van Der Marel GA, Van Boeckel CAA, Van Boom JH. Synthesis of a conformationally constrained heparin-like pentasaccharide Chemistry - a European Journal. 2: 1007-1013. DOI: 10.1002/chem.19960020817  0.097
1997 Timmers CM, Turner JJ, Ward CM, Van Der Marel GA, Kouwijzer MLCE, Grootenhuis PDJ, Van Boom JH. Synthesis and biological evaluation of a backbone-modified phytoalexin elicitor Chemistry - a European Journal. 3: 920-929.  0.097
1992 Said M, Noort D, Magdalou J, Ziegler JC, van der Marel GA, van Boom JH, Mulder GJ, Siest G. Selective and potent inhibition of different hepatic UDP-glucuronosyltransferase activities by omega,omega,omega-triphenylalcohols and UDP derivatives. Biochemical and Biophysical Research Communications. 187: 140-5. PMID 1520294 DOI: 10.1016/S0006-291X(05)81470-6  0.097
1999 Leeuwenburgh MA, Kulker C, Overkleeft HS, Van Der Marel GA, Van Boom JH. Synthesis of a trans-fused tricyclic ether using a novel differentially protected glucal Synlett. 1945-1947.  0.096
1996 Wijsman ER, Filippov D, Valentijn ARPM, Van Der Marel GA, Van Boom JH. Solid-support synthesis of di- and tetramannosylated tetrathymidylic acid Recueil Des Travaux Chimiques Des Pays-Bas-Journal of the Royal Netherlands. 115: 397-401.  0.094
2001 Turner JJ, Sikkema FD, Filippov DV, Van der Marel GA, Van Boom JH. Synthesis of β-lactams via ring opening of a serine derived aziridine Synlett. 1727-1730.  0.094
1997 Van Straten NCR, Duynstee HI, De Vroom E, Van Der Marel GA, Van Boom JH. Enzymatic cleavage of N-phenylacetyl-protected ethanolamine phosphates Liebigs Annales. 1215-1220.  0.094
2003 Sakharov DV, Jie AF, Filippov DV, Bekkers ME, van Boom JH, Rijken DC. Binding and retention of polycationic peptides and dendrimers in the vascular wall. Febs Letters. 537: 6-10. PMID 12606022 DOI: 10.1016/S0014-5793(03)00063-2  0.094
1987 Berkhout B, Schmidt BF, van Strien A, van Boom J, van Westrenen J, van Duin J. Lysis gene of bacteriophage MS2 is activated by translation termination at the overlapping coat gene. Journal of Molecular Biology. 195: 517-24. PMID 3656424 DOI: 10.1016/0022-2836(87)90180-X  0.093
2000 De Kort M, Luijendijk J, Van Der Marel GA, Van Boom JH. Synthesis of photoaffinity derivatives of adenophostin A European Journal of Organic Chemistry. 3085-3092.  0.091
1995 Ouwerkerk-Mahadevan S, van Boom JH, Dreef-Tromp MC, Ploemen JH, Meyer DJ, Mulder GJ. Glutathione analogues as novel inhibitors of rat and human glutathione S-transferase isoenzymes, as well as of glutathione conjugation in isolated rat hepatocytes and in the rat in vivo. The Biochemical Journal. 308: 283-90. PMID 7755575 DOI: 10.1042/bj3080283  0.088
2001 Van Hooft PAV, Van Der Marel GA, Van Boeckel CAA, Van Boom JH. Triisobutylaluminium mediated carbocyclisation of sugar derived spiroketals and ketosides Tetrahedron Letters. 42: 1769-1772. DOI: 10.1016/S0040-4039(00)02318-2  0.088
1996 Spronk CA, Slijper M, van Boom JH, Kaptein R, Boelens R. Formation of the hinge helix in the lac repressor is induced upon binding to the lac operator. Nature Structural Biology. 3: 916-9. PMID 8901866 DOI: 10.1038/Nsb1196-916  0.088
2003 De Visser PC, Van Helden M, Filippov DV, Van Der Marel GA, Drijfhout JW, Van Boom JH, Noort D, Overkleeft HS. A novel, base-labile fluorous amine protecting group: Synthesis and use as a tag in the purification of synthetic peptides Tetrahedron Letters. 44: 9013-9016. DOI: 10.1016/j.tetlet.2003.09.220  0.088
2001 De Koning MC, Filippov DV, Meeuwenoord N, Overhand M, Van der Marel GA, Van Boom JH. Synthesis of a PNA-peptide conjugate by chemical ligation Synlett. 1516-1518. DOI: 10.1055/S-2001-17455  0.087
1999 Van Delft FL, Valentijn ARPM, Van Der Marel GA, Van Boom JH. Preparation of 2,5-anhydrohexitols (part II). Intramolecular nucleophilic substitution of cyclic sulfates Journal of Carbohydrate Chemistry. 18: 191-207.  0.087
1984 Kempen HJ, Hoes C, van Boom JH, Spanjer HH, de Lange J, Langendoen A, van Berkel TJ. A water-soluble cholesteryl-containing trisgalactoside: synthesis, properties, and use in directing lipid-containing particles to the liver. Journal of Medicinal Chemistry. 27: 1306-12. PMID 6481766 DOI: 10.1021/JM00376A014  0.085
2000 De Kort M, Regenbogen AD, Overkleeft HS, John Challiss RA, Iwata Y, Miyamoto S, Van der Marel GA, Van Boom JH. Synthesis and biological evaluation of cyclophostin: A 5',6-tethered analog of adenophostin A Tetrahedron. 56: 5915-5928.  0.083
1993 Nijenhuis AA, Fokkens RH, Nibbering NM, van Oijen AH, de Bont HB, Liskamp RM, van Boom JH. Verification of the position of the phosphate group in some synthetic phosphopeptides by fast-atom bombardment and tandem mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 7: 774-9. PMID 8374165 DOI: 10.1002/Rcm.1290070818  0.083
2003 Kriek NMAJ, Filippov DV, Van Den Elst H, Meeuwenoord NJ, Tesser GI, Van Boom JH, Van Der Marel GA. Stepwise solid phase synthesis of uridylylated viral genome-linked peptides using uridylylated amino acid building blocks Tetrahedron. 59: 1589-1597. DOI: 10.1016/S0040-4020(03)00042-5  0.082
1990 O'Brian CA, Ward NE, Liskamp RM, de Bont DB, van Boom JH. N-myristyl-Lys-Arg-Thr-Leu-Arg: A novel protein kinase C inhibitor Biochemical Pharmacology. 39: 49-57. PMID 2153382 DOI: 10.1016/0006-2952(90)90647-4  0.082
1996 Ouwerkerk-Mahadevan S, van Boom JH, Mulder GJ. Isoenzyme-selective inhibition of glutathione conjugation in vivo: selective inhibition of the conjugation of S-2-Bromoisovalerylurea in the rat. The Journal of Pharmacology and Experimental Therapeutics. 276: 923-8. PMID 8786571  0.082
1999 Leeuwenburgh MA, Picasso S, Overkleeft HS, Van Der Marel GA, Vogel P, Van Boom JH. A short and flexible route to aza-β-(1→6)-C-disaccharides: Selective α-glycosidase inhibitors European Journal of Organic Chemistry. 1185-1189.  0.081
1984 Fluit AC, Baas PD, van Boom JH, Veeneman GH, Jansz HS. Gene a protein cleavage of recombinant plasmids containing the φX174 replication origin Nucleic Acids Research. 12: 6443-6454. DOI: 10.1093/nar/12.16.6443  0.081
1986 Verlaan-de Vries M, Bogaard ME, van den Elst H, van Boom JH, van der Eb AJ, Bos JL. A dot-blot screening procedure for mutated ras oncogenes using synthetic oligodeoxynucleotides Gene. 50: 313-320. PMID 3582981 DOI: 10.1016/0378-1119(86)90335-5  0.081
2004 De Koning MC, Filippov DV, Van Der Marel GA, Van Boom JH, Overhand M. Synthesis of peptide-PNA-peptide conjugates by semi-solid-phase chemical ligation combined with deactivation/capture of excess reactants European Journal of Organic Chemistry. 850-857. DOI: 10.1002/Ejoc.200300605  0.08
2001 Jansen WT, Verheul AF, Veeneman GH, van Boom JH, Snippe H. Revised interpretation of the immunological results obtained with pneumococcal polysaccharide 17F derived synthetic di-, tri- and tetrasaccharide conjugates in mice and rabbits. Vaccine. 20: 19-21. PMID 11567741 DOI: 10.1016/S0264-410X(01)00263-8  0.08
1999 Van Den Berg RJBHN, Noort D, Milder-Enacache ES, Van Der Marel GA, Van Boom JH, Benschop HP. Approach toward a generic treatment of gram-negative infections: Synthesis of haptens for catalytic antibody mediated cleavage of the interglycosidic bond in lipid A European Journal of Organic Chemistry. 2593-2600.  0.079
1996 Buijsman RC, Kuijpers WHA, Basten JEM, Kuyl-Yeheskiely E, Van Der Marel GA, Van Boeckel CAA, Van Boom JH. Synthesis of a pentasaccharide-oligonucleotide conjugate: A novel antithrombotic agent Chemistry - a European Journal. 2: 1572-1577. DOI: 10.1002/chem.19960021216  0.079
1983 Michels PA, Liu AY, Bernards A, Sloof P, Van der Bijl MM, Schinkel AH, Menke HH, Borst P, Veeneman GH, Tromp MC, Van Boom JH. Activation of the genes for variant surface glycoproteins 117 and 118 in Trypanosoma brucei. Journal of Molecular Biology. 166: 537-56. PMID 6306248 DOI: 10.1016/S0022-2836(83)80283-6  0.078
1992 De Ruiter GA, Smid P, Schols HA, Van Boom JH, Rombouts FM. Detection of fungal carbohydrate antigens by high-performance immunoaffinity chromatography using a protein A column with covalently linked immunoglobulin G. Journal of Chromatography. 584: 69-75. PMID 1487517 DOI: 10.1016/0378-4347(92)80010-N  0.078
1999 Duynstee HI, De Koning MC, Ovaa H, Van Der Marel GA, Van Boom JH. Synthesis of verbascoside: A dihydroxyphenylethyl glycoside with diverse bioactivity European Journal of Organic Chemistry. 2623-2632.  0.077
2004 Verhelst SHL, Magnée L, Wennekes T, Wiedenhof W, Van Der Marel GA, Overkleeft HS, Van Boeckel CAA, Van Boom JH. Glycosylation of cyclitols: Synthesis of neamine-type aminoglycosides European Journal of Organic Chemistry. 2404-2410. DOI: 10.1002/ejoc.200400020  0.077
2000 Leeuwenburgh MA, Litjens REJN, Codée JDC, Overkleeft HS, Van Der Marel GA, Van Boom JH. Radical cyclization of sugar-derived β-(alkynyloxy)acrylates: Synthesis of novel fused ethers Organic Letters. 2: 1275-1277.  0.077
1989 Kamphuis HJ, Notermans S, Veeneman GH, VAN Boom JH, Rombouts FM. A Rapid and Reliable Method for the Detection of Molds in Foods: Using the Latex Agglutination Assay. Journal of Food Protection. 52: 244-247. PMID 30991524 DOI: 10.4315/0362-028X-52.4.244  0.076
1999 Duynstee HI, De Koning MC, Van der Marel GA, Van Boom JH. An expeditious route to the synthesis of kelampayosides A and B Tetrahedron. 55: 9881-9898. DOI: 10.1016/S0040-4020(99)00527-X  0.075
2002 Filippov DV, Van Zoelen DJ, Oldfield SP, Van Der Marel GA, Overkleeft HS, Drijfhout JW, Van Boom JH. Use of benzyloxycarbonyl (Z)-based fluorophilic tagging reagents in the purification of synthetic peptides Tetrahedron Letters. 43: 7809-7812. DOI: 10.1016/S0040-4039(02)01723-9  0.074
2002 Biessen EA, Sliedregt-Bol K, 'T Hoen PA, Prince P, Van der Bilt E, Valentijn AR, Meeuwenoord NJ, Princen H, Bijsterbosch MK, Van der Marel GA, Van Boom JH, Van Berkel TJ. Design of a targeted peptide nucleic acid prodrug to inhibit hepatic human microsomal triglyceride transfer protein expression in hepatocytes. Bioconjugate Chemistry. 13: 295-302. PMID 11906267  0.074
1997 Overhand M, Pieterman E, Cohen LH, Valentijn ARPM, Van Der Marel GA, Van Boom JH. Synthesis of triphosphonated analogues of farnesyl pyrophosphate. Inhibitors of squalene synthase and protein:farnesyl transferase Bioorganic and Medicinal Chemistry Letters. 7: 2435-2440. DOI: 10.1016/S0960-894X(97)00448-4  0.073
1983 Sharma OK, Engels J, Jager A, Crea R, van Boom J, Goswami BB. 3'-O-methylated analogs of 2-5A as inhibitors of virus replication. Febs Letters. 158: 298-300. PMID 6873284 DOI: 10.1016/0014-5793(83)80599-7  0.072
1997 Van Straten NCR, Van der Marel GA, Van Boom JH. An expeditious route to the synthesis of adenophostin A Tetrahedron. 53: 6509-6522. DOI: 10.1016/S0040-4020(97)00307-4  0.072
2002 Codée JDC, Van der Marel GA, Van Boeckel CAA, Van Boom JH. Probing the heparin - Antithrombin III interaction using synthetic pentasaccharides bearing positively charged groups European Journal of Organic Chemistry. 3954-3965.  0.071
1999 Heetebrij RJ, Tromp RA, Van Der Marel GA, Van Boom JH, Reedijk J. A novel approach to site-specifically platinated oligonucleotides applying combinations of nucleobase protecting groups Chemical Communications. 1693-1694.  0.07
2000 Verheijen JC, Grotenbreg GM, Hart De Ruyter L, Van Der Klein PAM, Van Der Marel GA, Van Boom JH. An expeditious liquid-phase synthesis of cyclic peptide nucleic acids Tetrahedron Letters. 41: 3991-3995. DOI: 10.1016/S0040-4039(00)00536-0  0.07
2001 Turner JJ, Leeuwenburgh MA, Van Der Marel GA, Van Boom JH. A convenient route to α-amino acids with β-alkyne substituents from a serine derived aziridine Tetrahedron Letters. 42: 8713-8716. DOI: 10.1016/S0040-4039(01)01886-X  0.069
2004 Filippov DV, Van Den Elst H, Tromp CM, Van Der Marel GA, Van Boeckel CAA, Overkleeft HS, Van Boom JH. Parallel solid phase synthesis of tricomponent bisubstrate analogues as potential fucosyltransferase inhibitors Synlett. 773-778.  0.068
1997 Timmers CM, Dekker M, Buijsman RC, Van Der Marel GA, Ethell B, Anderson G, Burchell B, Mulder GJ, Van Boom JH. Synthesis and inhibitory effect of a trisubstrate transition state analogue for UDP glucuronosyltransferases Bioorganic and Medicinal Chemistry Letters. 7: 1501-1506. DOI: 10.1016/S0960-894X(97)00251-5  0.068
1998 Duynstee HI, Van Vliet MJ, Van Der Marel GA, Van Boom JH. An efficient synthesis of (R)-3-{(R)-3-[2-O-(α-L-rhamnopyranosyl)-α-L-rhamnopyranosyl] oxydecanoyl}oxydecanoic acid, a rhamnolipid from Pseudomonas aeruginosa European Journal of Organic Chemistry. 303-307.  0.068
2004 Verhelst SHL, Wennekes T, Van Der Marel GA, Overkleeft HS, Van Boeckel CAA, Van Boom JH. Synthesis of orthogonally protected 2-deoxystreptamine stereoisomers Tetrahedron. 60: 2813-2822. DOI: 10.1016/j.tet.2004.01.063  0.067
1996 Zegelaar-Jaarsveld K, Van Der Plas SC, Van Der Marel GA, Van Boom JH. Synthesis of haptenic trimers corresponding to the cell wall glycopeptidolipids of Mycobacterium avium serovar 12 Journal of Carbohydrate Chemistry. 15: 591-610.  0.066
1986 Turner DR, Mondragon A, Fairall L, Bloomer AC, Finch JT, Van Boom JH, Butler PJ. Oligonucleotide binding to the coat protein disk of tobacco mosaic virus. Possible steps in the mechanism of assembly. European Journal of Biochemistry / Febs. 157: 269-74. PMID 3709537 DOI: 10.1111/J.1432-1033.1986.TB09665.X  0.066
2000 Biessen EA, Valentijn AR, De Vrueh RL, Van De Bilt E, Sliedregt LA, Prince P, Bijsterbosch MK, Van Boom JH, Van Der Marel GA, Abrahams PJ, Van Berkel TJ. Novel hepatotrophic prodrugs of the antiviral nucleoside 9-(2-phosphonylmethoxyethyl)adenine with improved pharmacokinetics and antiviral activity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 14: 1784-92. PMID 10973928  0.066
2003 Carstensen EV, Duynstee HI, Van Der Marel GA, Van Boom JH, Nielsen J, Overkleeft HS, Overhand M. Synthesis of highly functionalized piperidines via a tandem retro-Michael-[2+3]-cycloaddition Journal of Carbohydrate Chemistry. 22: 241-252. DOI: 10.1002/CHIN.200340197  0.065
1986 Bos JL, Verlaan-de Vries M, Marshall CJ, Veeneman GH, van Boom JH, van der Eb AJ. A human gastric carcinoma contains a single mutated and an amplified normal allele of the Ki-ras oncogene Nucleic Acids Research. 14: 1209-1217. PMID 3951985 DOI: 10.1093/NAR/14.3.1209  0.065
1997 Valentijn ARPM, Van Der Marel GA, Sliedregt LAJM, Van Berkel TJC, Biessen EAL, Van Boom JH. Solid-phase synthesis of lysine-based cluster galactosides with high affinity for the asialoglycoprotein receptor Tetrahedron. 53: 759-770. DOI: 10.1016/S0040-4020(96)01018-6  0.065
1999 Van Delft FL, Valentijn ARPM, Van Der Marel GA, Van Boom JH. Preparation of 2,5-anhydrohexitols (part I). Silicon-directed stereocontrolled cyclization Journal of Carbohydrate Chemistry. 18: 165-190.  0.064
1997 Timmers CM, Verheijen JC, Van Der Marel GA, Van Boom JH. Use of Furanoid Glycals in Oligosaccharide Synthesis Synlett. 1997: 851-853.  0.063
1996 Duynstee HI, Wijsman ER, Van Der Marel GA, Van Boom JH. Synthesis of 2′-O-[(4″-O-sorboyl)-α-L-fucopyranosyl]inosine: A Shimofuridin analogue Synlett. 1996: 313-314.  0.062
1998 Filippov D, Kuyl-Yeheskiely E, Van Der Marel GA, Tesser GI, Van Boom JH. Synthesis of a nucleopeptide fragment from poliovirus genome Tetrahedron Letters. 39: 3597-3600. DOI: 10.1016/S0040-4039(98)00558-9  0.062
1993 Alonso de Velasco E, Verheul AF, Veeneman GH, Gomes LJ, van Boom JH, Verhoef J, Snippe H. Protein-conjugated synthetic di- and trisaccharides of pneumococcal type 17F exhibit a different immunogenicity and antigenicity than tetrasaccharide. Vaccine. 11: 1429-36. PMID 8310762 DOI: 10.1016/0264-410X(93)90172-T  0.06
2000 Van Den Nieuwendijk AMCH, Kriek NMAJ, Brussee J, Van Boom JH, Van Der Gen A. Stereoselective synthesis of (2R,5R)- and (2S,5R)-5-hydroxylysine European Journal of Organic Chemistry. 3683-3691.  0.058
2002 Berg RJBHNVD, Noort D, Van Der Marel GA, Van Boom JH, Benschop HP. Synthesis of pseudo-disaccharide analogues of lipid A: Haptens for the generation of antibodies with glycosidase activity towards lipid A Journal of Carbohydrate Chemistry. 21: 167-188. DOI: 10.1081/CAR-120004331  0.056
1995 Cohen LH, Valentijn AR, Roodenburg L, Van Leeuwen RE, Huisman RH, Lutz RJ, Van der Marel GA, Van Boom JH. Different analogues of farnesyl pyrophosphate inhibit squalene synthase and protein:farnesyltransferase to different extents. Biochemical Pharmacology. 49: 839-45. PMID 7702642 DOI: 10.1016/0006-2952(94)00454-T  0.054
1997 Filippov D, Timmers CM, Van der Marel GA, Van Boom JH. A study towards total synthesis of antibiotic agrocin 84 Nucleosides and Nucleotides. 16: 1403-1406.  0.052
1999 Sliedregt LA, Rensen PC, Rump ET, van Santbrink PJ, Bijsterbosch MK, Valentijn AR, van der Marel GA, van Boom JH, van Berkel TJ, Biessen EA. Design and synthesis of novel amphiphilic dendritic galactosides for selective targeting of liposomes to the hepatic asialoglycoprotein receptor. Journal of Medicinal Chemistry. 42: 609-18. PMID 10052968 DOI: 10.1021/jm981078h  0.052
1990 Veeneman GH, Brugghe HF, van den Elst H, van Boom JH. Solid-phase synthesis of a cell-wall component of Haemophilus (Actinobacillus) pleuropneumoniae serotype 2. Carbohydrate Research. 195: C1-4. PMID 2331698  0.05
1996 Heskamp BM, Broxterman HJG, Van Der Marel GA, Van Boom JH. Synthesis of guanosine 5′-(β-L-fucopyranosyl)-diphosphate revisited Journal of Carbohydrate Chemistry. 15: 611-622.  0.05
2005 Timmer MSM, Risseeuw MDP, Verdoes M, Filippov DV, Plaisier JR, Van Der Marel GA, Overkleeft HS, Van Boom JH. Synthesis of functionalized heterocycles via a tandem Staudinger/aza- Wittig/Ugi multicomponent reaction Tetrahedron Asymmetry. 16: 177-185. DOI: 10.1016/j.tetasy.2004.11.079  0.049
1984 Bos JL, Veriaan-de Vries M, Jansen AM, Veeneman GH, van Boom JH, van der Eb AJ. Three different mutations in codon 61 of the human N-ras gene detected by synthetic oligonucleotide hybridization Nucleic Acids Research. 12: 9155-9163. PMID 6595642 DOI: 10.1093/nar/12.23.9155  0.047
1998 Filippov D, Timmers CM, Roerdink AR, Van Der Marel GA, Van Boom JH. Synthesis of the antibiotically active part of agrocin 84 Tetrahedron Letters. 39: 4891-4894. DOI: 10.1016/S0040-4039(98)00888-0  0.047
1997 De Kort M, Valentijn ARPM, Van Der Marel GA, Van Boom JH. Synthesis of clustered disaccharide polyphosphate analogues of adenophostin A Tetrahedron Letters. 38: 7629-7632. DOI: 10.1016/S0040-4039(97)01811-X  0.043
1999 Turner JJ, Wilschut N, Overkleeft HS, Klaffke W, Van der Marel GA, Van Boom JH. Mitsunobu glycosylation of nitrobenzenesulfonamides: Novel route to Amadori rearrangement products Tetrahedron Letters. 40: 7039-7042. DOI: 10.1016/S0040-4039(99)01452-5  0.042
1992 Bijsterbosch MK, Bakkeren HF, Kempen HJ, Roelen HC, van Boom JH, van Berkel TJ. A monogalactosylated cholesterol derivative that specifically induces uptake of LDL by the liver. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology / American Heart Association. 12: 1153-60. PMID 1327096  0.035
2001 Van Hooft PAV, Van Swieten PF, Van der Marel GA, Van Boeckel CAA, Van Boom JH. Montmorillonite K-10 clay assisted transformation of vinylketoses into spirochromans and arylketoses Synlett. 269-271.  0.035
1999 Gregory RB, Wilcox RA, Berven LA, van Straten NC, van der Marel GA, van Boom JH, Barritt GJ. Evidence for the involvement of a small subregion of the endoplasmic reticulum in the inositol trisphosphate receptor-induced activation of Ca2+ inflow in rat hepatocytes. The Biochemical Journal. 341: 401-8. PMID 10393099 DOI: 10.1042/0264-6021:3410401  0.034
2004 Codée JDC, Van Den Bos LJ, Litjens REJN, Overkleeft HS, Van Boeckel CAA, Van Boom JH, Van Der Marel GA. Chemoselective glycosylations using sulfonium triflate activator systems Tetrahedron. 60: 1057-1064. DOI: 10.1016/j.tet.2003.11.084  0.018
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