| Year |
Citation |
Score |
| 2003 |
Rao BM, Girvin AT, Ciardelli T, Lauffenburger DA, Wittrup KD. Interleukin-2 mutants with enhanced alpha-receptor subunit binding affinity. Protein Engineering. 16: 1081-7. PMID 14983090 DOI: 10.1093/Protein/Gzg111 |
0.71 |
|
| 2002 |
Liparoto SF, Myszka DG, Wu Z, Goldstein B, Laue TM, Ciardelli TL. Analysis of the role of the interleukin-2 receptor gamma chain in ligand binding. Biochemistry. 41: 2543-51. PMID 11851401 DOI: 10.1021/Bi011692M |
0.759 |
|
| 2000 |
Fallon EM, Liparoto SF, Lee KJ, Ciardelli TL, Lauffenburger DA. Increased endosomal sorting of ligand to recycling enhances potency of an interleukin-2 analog. The Journal of Biological Chemistry. 275: 6790-7. PMID 10702236 DOI: 10.1074/jbc.275.10.6790 |
0.761 |
|
| 1999 |
Liparoto SF, Ciardelli TL. Biosensor analysis of the interleukin-2 receptor complex. Journal of Molecular Recognition : Jmr. 12: 316-21. PMID 10556880 DOI: 10.1002/(Sici)1099-1352(199909/10)12:5<316::Aid-Jmr468>3.0.Co;2-1 |
0.75 |
|
| 1999 |
Wu Z, Goldstein B, Laue TM, Liparoto SF, Nemeth MJ, Ciardelli TL. Solution assembly of the pseudo-high affinity and intermediate affinity interleukin-2 receptor complexes. Protein Science : a Publication of the Protein Society. 8: 482-9. PMID 10091650 DOI: 10.1110/Ps.8.3.482 |
0.758 |
|
| 1998 |
Nielsen OH, Kirman I, Johnson K, Giedlin M, Ciardelli T. The circulating common gamma chain (CD132) in inflammatory bowel disease. The American Journal of Gastroenterology. 93: 323-8. PMID 9517632 DOI: 10.1111/j.1572-0241.1998.00323.x |
0.422 |
|
| 1997 |
Wang R, Ciardelli TL, Russell JH. Partial signaling by cytokines: cytokine regulation of cell cycle and Fas-dependent, activation-induced death in CD4+ subsets. Cellular Immunology. 182: 152-60. PMID 9514696 DOI: 10.1006/Cimm.1997.1220 |
0.62 |
|
| 1997 |
Lee BL, Ciardelli TL. Structural modifications of interleukin-2 at positions 47 and 65. Biochemical and Biophysical Research Communications. 233: 309-15. PMID 9144530 DOI: 10.1006/Bbrc.1997.6453 |
0.55 |
|
| 1997 |
Buchli PJ, Wu Z, Ciardelli TL. The functional display of interleukin-2 on filamentous phage. Archives of Biochemistry and Biophysics. 339: 79-84. PMID 9056236 DOI: 10.1006/Abbi.1996.9853 |
0.738 |
|
| 1996 |
Myszka DG, Arulanantham PR, Sana T, Wu Z, Morton TA, Ciardelli TL. Kinetic analysis of ligand binding to interleukin-2 receptor complexes created on an optical biosensor surface. Protein Science : a Publication of the Protein Society. 5: 2468-78. PMID 8976555 DOI: 10.1002/Pro.5560051209 |
0.683 |
|
| 1996 |
Cardi G, Ciardelli TL, Ernstoff MS. Therapeutic applications of cytokines for immunostimulation and immunosuppression: an update. Progress in Drug Research. Fortschritte Der Arzneimittelforschung. ProgrèS Des Recherches Pharmaceutiques. 47: 211-50. PMID 8961768 DOI: 10.1007/978-3-0348-8998-8_6 |
0.559 |
|
| 1996 |
Chang DZ, Wu Z, Ciardelli TL. A point mutation in interleukin-2 that alters ligand internalization. The Journal of Biological Chemistry. 271: 13349-55. PMID 8662876 DOI: 10.1074/Jbc.271.23.13349 |
0.693 |
|
| 1996 |
vanderSpek JC, Sutherland JA, Ratnarathorn M, Howland K, Ciardelli TL, Murphy JR. DAB389 interleukin-2 receptor binding domain mutations. Cytotoxic probes for studies of ligand-receptor interactions. The Journal of Biological Chemistry. 271: 12145-9. PMID 8647806 DOI: 10.1074/jbc.271.21.12145 |
0.683 |
|
| 1996 |
Wu Z, Johnson KW, Goldstein B, Laue TM, Ciardelli TL. Solution assembly of cytokine receptor ectodomain complexes Techniques in Protein Chemistry. 7: 45-56. DOI: 10.1016/S1080-8914(96)80008-1 |
0.621 |
|
| 1995 |
Chang DZ, Tasayco ML, Ciardelli TL. Structural analogs of interleukin-2: a point mutation that facilitates biological response. Molecular Pharmacology. 47: 206-11. PMID 7838130 |
0.669 |
|
| 1995 |
Wu Z, Johnson KW, Choi Y, Ciardelli TL. Ligand binding analysis of soluble interleukin-2 receptor complexes by surface plasmon resonance. The Journal of Biological Chemistry. 270: 16045-51. PMID 7608166 DOI: 10.1074/Jbc.270.27.16045 |
0.507 |
|
| 1995 |
Wu Z, Johnson KW, Goldstein B, Choi Y, Eaton SF, Laue TM, Ciardelli TL. Solution assembly of a soluble, heteromeric, high affinity interleukin-2 receptor complex. The Journal of Biological Chemistry. 270: 16039-44. PMID 7608165 DOI: 10.1074/Jbc.270.27.16039 |
0.533 |
|
| 1995 |
Wu Z, Johnson KW, Ciardelli TL. Ligand binding analysis of interleukin-2 receptor complexes using surface plasmon resonance. Journal of Immunological Methods. 183: 127-30. PMID 7602130 DOI: 10.1016/0022-1759(95)00040-H |
0.498 |
|
| 1994 |
Buchli P, Ciardelli T. Structural and biologic properties of a human aspartic acid-126 interleukin-2 analog. Archives of Biochemistry and Biophysics. 307: 411-5. PMID 8274030 DOI: 10.1006/Abbi.1993.1608 |
0.683 |
|
| 1994 |
Berndt WG, Chang DZ, Smith KA, Ciardelli TL. Mutagenic analysis of a receptor contact site on interleukin-2: preparation of an IL-2 analog with increased potency. Biochemistry. 33: 6571-7. PMID 8204593 DOI: 10.1021/Bi00187A026 |
0.701 |
|
| 1994 |
Sana TR, Wu Z, Smith KA, Ciardelli TL. Expression and ligand binding characterization of the beta-subunit (p75) ectodomain of the interleukin-2 receptor. Biochemistry. 33: 5838-45. PMID 8180212 DOI: 10.1021/Bi00185A023 |
0.602 |
|
| 1994 |
Nakarai T, Robertson MJ, Streuli M, Wu Z, Ciardelli TL, Smith KA, Ritz J. Interleukin 2 receptor gamma chain expression on resting and activated lymphoid cells. The Journal of Experimental Medicine. 180: 241-51. PMID 8006584 DOI: 10.1084/jem.180.1.241 |
0.541 |
|
| 1994 |
Wu Z, Eaton SF, Laue TM, Johnson KW, Sana TR, Ciardelli TL. Coiled-coil molecular recognition: directed solution assembly of receptor ectodomains. Protein Engineering. 7: 1137-44. PMID 7831285 DOI: 10.1093/Protein/7.9.1137 |
0.702 |
|
| 1994 |
Johnson K, Granzow R, Creasey A, Ciardelli T. Ligand Binding Analyses and Functional Activity of Interleukin-2 Receptor Ectodomains Methods. 6: 199-205. DOI: 10.1006/Meth.1994.1022 |
0.635 |
|
| 1993 |
Lee BL, Ciardelli TL. Conformation studies of interleukin-2 mutants: Generation of partial agonists Protein Engineering, Design and Selection. 6: 115. DOI: 10.1093/Protein/6.Supplement.115-B |
0.36 |
|
| 1992 |
Landgraf BE, Goldstein B, Williams DP, Murphy JR, Sana TR, Smith KA, Ciardelli TL. Recombinant interleukin-2 analogs. Dynamic probes for receptor structure. The Journal of Biological Chemistry. 267: 18511-9. PMID 1526987 |
0.693 |
|
| 1991 |
Landgraf BE, Williams DP, Murphy JR, Smith KA, Ciardelli TL. Conformational perturbation of interleukin-2: a strategy for the design of cytokine analogs. Proteins. 9: 207-16. PMID 2006138 DOI: 10.1002/Prot.340090306 |
0.663 |
|
| 1989 |
Ciardelli T, Smith KA. Interleukin 2: prototype for a new generation of immunoactive pharmaceuticals. Trends in Pharmacological Sciences. 10: 239-43. PMID 2672465 DOI: 10.1016/0165-6147(89)90269-1 |
0.588 |
|
| 1988 |
Smith LI, Bodwell JE, Mendel DB, Ciardelli T, North WG, Munck A. Identification of cysteine-644 as the covalent site of attachment of dexamethasone 21-mesylate to murine glucocorticoid receptors in WEHI-7 cells. Biochemistry. 27: 3747-53. PMID 3408724 DOI: 10.1021/Bi00410A034 |
0.354 |
|
| 1988 |
Ciardelli TL, Landgraf B, Gadski R, Strnad J, Cohen FE, Smith KA. A design approach to the structural analysis of interleukin-2. Journal of Molecular Recognition : Jmr. 1: 42-7. PMID 3273651 DOI: 10.1002/Jmr.300010108 |
0.347 |
|
| 1986 |
Cohen FE, Kosen PA, Kuntz ID, Epstein LB, Ciardelli TL, Smith KA. Structure-activity studies of interleukin-2 Science. 234: 349-352. PMID 3489989 DOI: 10.1126/Science.3489989 |
0.592 |
|
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