| Year |
Citation |
Score |
| 2023 |
Theusch E, Ting FY, Qin Y, Stevens K, Naidoo D, King SM, Yang N, Orr J, Han BY, Cyster JG, Chen YI, Rotter JI, Krauss RM, Medina MW. Participant-derived cell line transcriptomic analyses and mouse studies reveal a role for ZNF335 in plasma cholesterol statin response. Biorxiv : the Preprint Server For Biology. PMID 37397985 DOI: 10.1101/2023.06.14.544860 |
0.318 |
|
| 2022 |
Kanoni S, Graham SE, Wang Y, Surakka I, Ramdas S, Zhu X, Clarke SL, Bhatti KF, Vedantam S, Winkler TW, Locke AE, Marouli E, Zajac GJM, Wu KH, Ntalla I, ... ... Theusch E, et al. Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis. Genome Biology. 23: 268. PMID 36575460 DOI: 10.1186/s13059-022-02837-1 |
0.301 |
|
| 2022 |
Ramdas S, Judd J, Graham SE, Kanoni S, Wang Y, Surakka I, Wenz B, Clarke SL, Chesi A, Wells A, Bhatti KF, Vedantam S, Winkler TW, Locke AE, Marouli E, ... ... Theusch E, et al. A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids. American Journal of Human Genetics. 109: 1366-1387. PMID 35931049 DOI: 10.1016/j.ajhg.2022.06.012 |
0.351 |
|
| 2022 |
Trompet S, Postmus I, Warren HR, Noordam R, Smit RAJ, Theusch E, Li X, Arsenault B, Chasman DI, Hitman GA, Munroe PB, Rotter JI, Psaty BM, Caulfield MJ, Krauss RM, et al. The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction. Frontiers in Pharmacology. 12: 679857. PMID 35069183 DOI: 10.3389/fphar.2021.679857 |
0.334 |
|
| 2021 |
Graham SE, Clarke SL, Wu KH, Kanoni S, Zajac GJM, Ramdas S, Surakka I, Ntalla I, Vedantam S, Winkler TW, Locke AE, Marouli E, Hwang MY, Han S, Narita A, ... ... Theusch E, et al. The power of genetic diversity in genome-wide association studies of lipids. Nature. PMID 34887591 DOI: 10.1038/s41586-021-04064-3 |
0.399 |
|
| 2021 |
Pott J, Gadin J, Theusch E, Kleber ME, Delgado GE, Kirsten H, Hauck SM, Burkhardt R, Scharnagl H, Krauss RM, Loeffler M, März W, Thiery J, Silveira A, Vant Hooft FM, et al. Meta-GWAS of PCSK9 levels detects two novel loci at APOB and TM6SF2. Human Molecular Genetics. PMID 34590679 DOI: 10.1093/hmg/ddab279 |
0.336 |
|
| 2021 |
Veturi Y, Lucas A, Bradford Y, Hui D, Dudek S, Theusch E, Verma A, Miller JE, Kullo I, Hakonarson H, Sleiman P, Schaid D, Stein CM, Edwards DRV, Feng Q, et al. A unified framework identifies new links between plasma lipids and diseases from electronic medical records across large-scale cohorts. Nature Genetics. PMID 34140684 DOI: 10.1038/s41588-021-00879-y |
0.334 |
|
| 2021 |
Kuang YL, Theusch E, M Krauss R, W Medina M. Identifying genetic modulators of statin response using subject-derived lymphoblastoid cell lines. Pharmacogenomics. 22: 413-421. PMID 33858191 DOI: 10.2217/pgs-2020-0197 |
0.329 |
|
| 2020 |
Theusch E, Chen YI, Rotter JI, Krauss RM, Medina MW. Genetic variants modulate gene expression statin response in human lymphoblastoid cell lines. Bmc Genomics. 21: 555. PMID 32787775 DOI: 10.1186/S12864-020-06966-4 |
0.497 |
|
| 2019 |
Smit RAJ, Trompet S, Leong A, Goodarzi MO, Postmus I, Warren H, Theusch E, Barnes MR, Arsenault BJ, Li X, Feng Q, Chasman DI, Cupples LA, Hitman GA, Krauss RM, et al. Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study. The Pharmacogenomics Journal. PMID 31801993 DOI: 10.1038/S41397-019-0125-X |
0.377 |
|
| 2019 |
Liu K, Theusch E, Zhou Y, Ashuach T, Dose AC, Bickel PJ, Medina MW, Huang H. GeneFishing to reconstruct context specific portraits of biological processes. Proceedings of the National Academy of Sciences of the United States of America. PMID 31484776 DOI: 10.1073/Pnas.1820340116 |
0.374 |
|
| 2018 |
Kim K, Theusch E, Kuang YL, Dose A, Mitchel K, Cubitt C, Chen YI, Krauss RM, Medina MW. ZNF542P is a pseudogene associated with LDL response to simvastatin treatment. Scientific Reports. 8: 12443. PMID 30127457 DOI: 10.1038/S41598-018-30859-Y |
0.456 |
|
| 2018 |
Hoffmann TJ, Theusch E, Haldar T, Ranatunga DK, Jorgenson E, Medina MW, Kvale MN, Kwok PY, Schaefer C, Krauss RM, Iribarren C, Risch N. A large electronic-health-record-based genome-wide study of serum lipids. Nature Genetics. PMID 29507422 DOI: 10.1038/S41588-018-0064-5 |
0.477 |
|
| 2017 |
Alvarez MI, Glover LC, Luo P, Wang L, Theusch E, Oehlers SH, Walton EM, Tram TTB, Kuang YL, Rotter JI, McClean CM, Chinh NT, Medina MW, Tobin DM, Dunstan SJ, et al. Human genetic variation in VAC14 regulates Salmonella invasion and typhoid fever through modulation of cholesterol. Proceedings of the National Academy of Sciences of the United States of America. PMID 28827342 DOI: 10.1073/Pnas.1706070114 |
0.443 |
|
| 2016 |
Kim MJ, Yu CY, Theusch E, Naidoo D, Stevens K, Kuang YL, Schuetz E, Chaudhry AS, Medina MW. SUGP1 is a novel regulator of cholesterol metabolism. Human Molecular Genetics. PMID 27206982 DOI: 10.1093/Hmg/Ddw151 |
0.427 |
|
| 2016 |
Mitchel K, Theusch E, Cubitt C, Dosé AC, Stevens K, Naidoo D, Medina MW. RP1-13D10.2 Is a Novel Modulator of Statin-Induced Changes in Cholesterol. Circulation. Cardiovascular Genetics. PMID 27071970 DOI: 10.1161/Circgenetics.115.001274 |
0.425 |
|
| 2016 |
Theusch E, Kim K, Stevens K, Smith JD, Chen YI, Rotter JI, Nickerson DA, Medina MW. Statin-induced expression change of INSIG1 in lymphoblastoid cell lines correlates with plasma triglyceride statin response in a sex-specific manner. The Pharmacogenomics Journal. PMID 26927283 DOI: 10.1038/Tpj.2016.12 |
0.408 |
|
| 2016 |
Chhibber A, French CE, Yee SW, Gamazon ER, Theusch E, Qin X, Webb A, Papp AC, Wang A, Simmons CQ, Konkashbaev A, Chaudhry AS, Mitchel K, Stryke D, Ferrin TE, et al. Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines. The Pharmacogenomics Journal. PMID 26856248 DOI: 10.1038/Tpj.2015.93 |
0.302 |
|
| 2015 |
Luzum JA, Theusch E, Taylor KD, Wang A, Sadee W, Binkley PF, Krauss RM, Medina MW, Kitzmiller JP. Individual and Combined Associations of Genetic Variants in CYP3A4, CYP3A5, and SLCO1B1 With Simvastatin and Simvastatin Acid Plasma Concentrations. Journal of Cardiovascular Pharmacology. 66: 80-5. PMID 26164721 DOI: 10.1097/Fjc.0000000000000246 |
0.387 |
|
| 2014 |
Kim K, Bolotin E, Theusch E, Huang H, Medina MW, Krauss RM. Prediction of LDL cholesterol response to statin using transcriptomic and genetic variation. Genome Biology. 15: 460. PMID 25316374 DOI: 10.1186/S13059-014-0460-9 |
0.466 |
|
| 2014 |
Theusch E, Medina MW, Rotter JI, Krauss RM. Ancestry and other genetic associations with plasma PCSK9 response to simvastatin. Pharmacogenetics and Genomics. 24: 492-500. PMID 25089948 DOI: 10.1097/Fpc.0000000000000081 |
0.461 |
|
| 2014 |
Medina MW, Bauzon F, Naidoo D, Theusch E, Stevens K, Schilde J, Schubert C, Mangravite LM, Rudel LL, Temel RE, Runz H, Krauss RM. Transmembrane protein 55B is a novel regulator of cellular cholesterol metabolism. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1917-23. PMID 25035345 DOI: 10.1161/Atvbaha.113.302806 |
0.409 |
|
| 2014 |
Yu CY, Theusch E, Lo K, Mangravite LM, Naidoo D, Kutilova M, Medina MW. HNRNPA1 regulates HMGCR alternative splicing and modulates cellular cholesterol metabolism. Human Molecular Genetics. 23: 319-32. PMID 24001602 DOI: 10.1093/Hmg/Ddt422 |
0.434 |
|
| 2012 |
Medina MW, Theusch E, Naidoo D, Bauzon F, Stevens K, Mangravite LM, Kuang YL, Krauss RM. RHOA is a modulator of the cholesterol-lowering effects of statin. Plos Genetics. 8: e1003058. PMID 23166513 DOI: 10.1371/Journal.Pgen.1003058 |
0.465 |
|
| 2011 |
Theusch E, Gitschier J. Absolute pitch twin study and segregation analysis. Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 14: 173-8. PMID 21425900 DOI: 10.1375/Twin.14.2.173 |
0.539 |
|
| 2009 |
Theusch E, Basu A, Gitschier J. Genome-wide study of families with absolute pitch reveals linkage to 8q24.21 and locus heterogeneity. American Journal of Human Genetics. 85: 112-9. PMID 19576568 DOI: 10.1016/J.Ajhg.2009.06.010 |
0.524 |
|
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