Year |
Citation |
Score |
2023 |
Masson HO, Samoudi M, Robinson CM, Kuo CC, Weiss L, Shams Ud Doha K, Campos A, Tejwani V, Dahodwala H, Menard P, Voldborg BG, Robasky B, Sharfstein ST, Lewis NE. Inferring secretory and metabolic pathway activity from omic data with secCellFie. Metabolic Engineering. PMID 38145748 DOI: 10.1016/j.ymben.2023.12.006 |
0.762 |
|
2023 |
Masson HO, Samoudi M, Robinson CM, Kuo CC, Weiss L, Ud Doha KS, Campos A, Tejwani V, Dahodwala H, Menard P, Voldborg BG, Sharfstein ST, Lewis NE. Inferring secretory and metabolic pathway activity from omic data with secCellFie. Biorxiv : the Preprint Server For Biology. PMID 37205389 DOI: 10.1101/2023.05.04.539316 |
0.763 |
|
2022 |
Dahodwala H, Amenyah SD, Nicoletti S, Henry MN, Lees-Murdock DJ, Sharfstein ST. Evaluation of site-specific methylation of the CMV promoter and its role in CHO cell productivity of a recombinant monoclonal antibody. Antibody Therapeutics. 5: 121-129. PMID 35719211 DOI: 10.1093/abt/tbac010 |
0.729 |
|
2022 |
Thacker BE, Thorne KJ, Cartwright C, Park J, Glass K, Chea A, Kellman BP, Lewis NE, Wang Z, Di Nardo A, Sharfstein ST, Jeske W, Walenga J, Hogwood J, Gray E, et al. Multiplex genome editing of mammalian cells for producing recombinant heparin. Metabolic Engineering. PMID 35038554 DOI: 10.1016/j.ymben.2022.01.002 |
0.314 |
|
2021 |
Tejwani V, Chaudhari M, Rai T, Sharfstein ST. High-throughput and automation advances for accelerating single-cell cloning, monoclonality and early phase clone screening steps in mammalian cell line development for biologics production. Biotechnology Progress. e3208. PMID 34478248 DOI: 10.1002/btpr.3208 |
0.344 |
|
2020 |
Muralidharan-Chari V, Wurz Z, Doyle F, Henry M, Diendorfer A, Tenenbaum SA, Borth N, Eveleth E, Sharfstein ST. PTSelect™: A post-transcriptional technology that enables rapid establishment of stable CHO cell lines and surveillance of clonal variation. Journal of Biotechnology. PMID 33115662 DOI: 10.1016/j.jbiotec.2020.09.025 |
0.372 |
|
2020 |
Amini N, Paluh JL, Xie Y, Saxena V, Sharfstein ST. Insulin production from hiPSC-derived pancreatic cells in a novel wicking matrix bioreactor. Biotechnology and Bioengineering. PMID 32314809 DOI: 10.1002/Bit.27359 |
0.404 |
|
2020 |
Sharfstein S. Review for "A Class of Low‐Cost Alternatives to Kifunensine for Increasing High Mannose N‐linked glycosylation for Monoclonal Antibody Production in CHO Cells" Biotechnology Progress. DOI: 10.1002/Btpr.3076/V2/Review1 |
0.374 |
|
2019 |
Dahodwala H, Kaushik P, Tejwani V, Kuo CC, Menard P, Henry M, Voldborg BG, Lewis NE, Meleady P, Sharfstein ST. Increased mAb production in amplified CHO cell lines is associated with increased interaction of CREB1 with transgene promoter. Current Research in Biotechnology. 1: 49-57. PMID 32577618 DOI: 10.1016/j.crbiot.2019.09.001 |
0.775 |
|
2019 |
Li S, Cha SW, Hefner K, Hizal DB, Bowen MA, Chaerkady R, Cole RN, Tejwani V, Kaushik P, Henry M, Meleady P, Sharfstein ST, Betenbaugh MJ, Bafna V, Lewis NE. Proteogenomic annotation of the Chinese hamster reveals extensive novel translation events and endogenous retroviral elements. Journal of Proteome Research. PMID 31020842 DOI: 10.1021/Acs.Jproteome.8B00935 |
0.37 |
|
2019 |
Sharfstein S. Review for "Effective temperature shift strategy development and scale confirmation for simultaneous optimization of protein productivity and quality in Chinese hamster ovary cells" Biotechnology Progress. DOI: 10.1002/Btpr.2959/V1/Review2 |
0.354 |
|
2018 |
Thacker BE, Sharfstein ST. Metabolic engineering of mammalian cells to produce heparan sulfates. Emerging Topics in Life Sciences. 2: 443-452. PMID 33525792 DOI: 10.1042/ETLS20180007 |
0.309 |
|
2018 |
Tejwani V, Andersen MR, Nam JH, Sharfstein ST. Glycoengineering in CHO cells: Advances in systems biology. Biotechnology Journal. PMID 29316325 DOI: 10.1002/Biot.201700234 |
0.453 |
|
2018 |
Sharfstein ST. Non-protein biologic therapeutics. Current Opinion in Biotechnology. 53: 65-75. PMID 29289799 DOI: 10.1016/J.Copbio.2017.12.014 |
0.332 |
|
2017 |
Dahodwala H, Sharfstein ST. Biosimilars: Imitation Games. Acs Medicinal Chemistry Letters. 8: 690-693. PMID 28740599 DOI: 10.1021/Acsmedchemlett.7B00199 |
0.728 |
|
2017 |
Dahodwala H, Sharfstein ST. The 'Omics Revolution in CHO Biology: Roadmap to Improved CHO Productivity. Methods in Molecular Biology (Clifton, N.J.). 1603: 153-168. PMID 28493129 DOI: 10.1007/978-1-4939-6972-2_10 |
0.765 |
|
2016 |
Torrejon KY, Papke EL, Halman JR, Bergkvist M, Danias J, Sharfstein ST, Xie Y. TGFβ2-induced outflow alterations in a bioengineered trabecular meshwork are offset by a rho-associated kinase inhibitor. Scientific Reports. 6: 38319. PMID 27924833 DOI: 10.1038/Srep38319 |
0.302 |
|
2016 |
Oduah EI, Linhardt RJ, Sharfstein ST. Heparin: Past, Present, and Future. Pharmaceuticals (Basel, Switzerland). 9. PMID 27384570 DOI: 10.3390/Ph9030038 |
0.374 |
|
2015 |
Torrejon KY, Papke EL, Halman JR, Stolwijk J, Dautriche CN, Bergkvist M, Danias J, Sharfstein ST, Xie Y. Bioengineered glaucomatous 3D human trabecular meshwork as an in vitro disease model. Biotechnology and Bioengineering. PMID 26615056 DOI: 10.1002/Bit.25899 |
0.314 |
|
2015 |
Dautriche CN, Tian Y, Xie Y, Sharfstein ST. A Closer Look at Schlemm's Canal Cell Physiology: Implications for Biomimetics. Journal of Functional Biomaterials. 6: 963-85. PMID 26402712 DOI: 10.3390/Jfb6030963 |
0.341 |
|
2015 |
Dautriche CN, Szymanski D, Kerr M, Torrejon KY, Bergkvist M, Xie Y, Danias J, Stamer WD, Sharfstein ST. A biomimetic Schlemm's canal inner wall: A model to study outflow physiology, glaucoma pathology and high-throughput drug screening. Biomaterials. 65: 86-92. PMID 26142779 DOI: 10.1016/J.Biomaterials.2015.06.034 |
0.39 |
|
2015 |
Baik JY, Dahodwala H, Oduah E, Talman L, Gemmill TR, Gasimli L, Datta P, Yang B, Li G, Zhang F, Li L, Linhardt RJ, Campbell AM, Gorfien SF, Sharfstein ST. Optimization of bioprocess conditions improves production of a CHO cell-derived, bioengineered heparin. Biotechnology Journal. 10: 1067-81. PMID 26037948 DOI: 10.1002/Biot.201400665 |
0.772 |
|
2015 |
Datta P, Yang B, Linhardt RJ, Sharfstein ST. Modulation of heparan sulfate biosynthesis by sodium butyrate in recombinant CHO cells. Cytotechnology. 67: 223-35. PMID 24468831 DOI: 10.1007/S10616-013-9677-9 |
0.405 |
|
2014 |
Dautriche CN, Xie Y, Sharfstein ST. Walking through trabecular meshwork biology: Toward engineering design of outflow physiology. Biotechnology Advances. 32: 971-83. PMID 24806891 DOI: 10.1016/J.Biotechadv.2014.04.012 |
0.32 |
|
2014 |
Gasimli L, Glass CA, Datta P, Yang B, Li G, Gemmill TR, Baik JY, Sharfstein ST, Esko JD, Linhardt RJ. Bioengineering murine mastocytoma cells to produce anticoagulant heparin. Glycobiology. 24: 272-80. PMID 24326668 DOI: 10.1093/Glycob/Cwt108 |
0.387 |
|
2014 |
Datta P, Meli L, Li L, Migliore N, Schaefer E, Sharfstein ST, Dordick JS, Linhardt RJ. Microarray platform affords improved product analysis in mammalian cell growth studies. Biotechnology Journal. 9: 386-95. PMID 24227746 DOI: 10.1002/Biot.201300288 |
0.461 |
|
2014 |
Dahodwala H, Sharfstein ST. Role of epigenetics in expression of recombinant proteins from mammalian cells Pharmaceutical Bioprocessing. 2: 403-419. DOI: 10.4155/Pbp.14.47 |
0.762 |
|
2014 |
Mason M, Sweeney B, Cain K, Stephens P, Sharfstein S. Reduced Culture Temperature Differentially Affects Expression and Biophysical Properties of Monoclonal Antibody Variants Antibodies. 3: 253-271. DOI: 10.3390/Antib3030253 |
0.384 |
|
2013 |
Datta P, Li G, Yang B, Zhao X, Baik JY, Gemmill TR, Sharfstein ST, Linhardt RJ. Bioengineered Chinese hamster ovary cells with Golgi-targeted 3-O-sulfotransferase-1 biosynthesize heparan sulfate with an antithrombin-binding site. The Journal of Biological Chemistry. 288: 37308-18. PMID 24247246 DOI: 10.1074/Jbc.M113.519033 |
0.347 |
|
2013 |
Torrejon KY, Pu D, Bergkvist M, Danias J, Sharfstein ST, Xie Y. Recreating a human trabecular meshwork outflow system on microfabricated porous structures. Biotechnology and Bioengineering. 110: 3205-18. PMID 23775275 DOI: 10.1002/Bit.24977 |
0.362 |
|
2013 |
Datta P, Linhardt RJ, Sharfstein ST. An 'omics approach towards CHO cell engineering. Biotechnology and Bioengineering. 110: 1255-71. PMID 23322664 DOI: 10.1002/Bit.24841 |
0.488 |
|
2012 |
Baik JY, Wang CL, Yang B, Linhardt RJ, Sharfstein S. Toward a bioengineered heparin: challenges and strategies for metabolic engineering of mammalian cells. Bioengineered. 3: 227-31. PMID 22714556 DOI: 10.4161/Bioe.20902 |
0.432 |
|
2012 |
Zhang H, Lee MY, Hogg MG, Dordick JS, Sharfstein ST. High-throughput transfection of interfering RNA into a 3D cell-culture chip. Small (Weinheim An Der Bergstrasse, Germany). 8: 2091-8. PMID 22511323 DOI: 10.1002/Smll.201102205 |
0.58 |
|
2012 |
Mason M, Sweeney B, Cain K, Stephens P, Sharfstein ST. Identifying bottlenecks in transient and stable production of recombinant monoclonal-antibody sequence variants in Chinese hamster ovary cells. Biotechnology Progress. 28: 846-55. PMID 22467228 DOI: 10.1002/Btpr.1542 |
0.369 |
|
2012 |
Baik JY, Gasimli L, Yang B, Datta P, Zhang F, Glass CA, Esko JD, Linhardt RJ, Sharfstein ST. Metabolic engineering of Chinese hamster ovary cells: towards a bioengineered heparin. Metabolic Engineering. 14: 81-90. PMID 22326251 DOI: 10.1016/J.Ymben.2012.01.008 |
0.463 |
|
2012 |
Dahodwala H, Nowey M, Mitina T, Sharfstein ST. Effects of clonal variation on growth, metabolism, and productivity in response to trophic factor stimulation: a study of Chinese hamster ovary cells producing a recombinant monoclonal antibody. Cytotechnology. 64: 27-41. PMID 21822681 DOI: 10.1007/S10616-011-9388-Z |
0.758 |
|
2011 |
Kiehl TR, Shen D, Khattak SF, Jian Li Z, Sharfstein ST. Observations of cell size dynamics under osmotic stress. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 79: 560-9. PMID 21656664 DOI: 10.1002/Cyto.A.21076 |
0.428 |
|
2011 |
Baughman AC, Sharfstein ST, Martin LL. A flexible state-space approach for the modeling of metabolic networks II: advanced interrogation of hybridoma metabolism. Metabolic Engineering. 13: 138-49. PMID 21163360 DOI: 10.1016/J.Ymben.2010.12.003 |
0.317 |
|
2010 |
Zhang H, Lee MY, Hogg MG, Dordick JS, Sharfstein ST. Gene delivery in three-dimensional cell cultures by superparamagnetic nanoparticles. Acs Nano. 4: 4733-43. PMID 20731451 DOI: 10.1021/Nn9018812 |
0.59 |
|
2010 |
Shen D, Kiehl TR, Khattak SF, Li ZJ, He A, Kayne PS, Patel V, Neuhaus IM, Sharfstein ST. Transcriptomic responses to sodium chloride-induced osmotic stress: a study of industrial fed-batch CHO cell cultures. Biotechnology Progress. 26: 1104-15. PMID 20306541 DOI: 10.1002/Btpr.398 |
0.489 |
|
2010 |
Baughman AC, Huang X, Sharfstein ST, Martin LL. On the dynamic modeling of mammalian cell metabolism and mAb production Computers and Chemical Engineering. 34: 210-222. DOI: 10.1016/J.Compchemeng.2009.06.019 |
0.304 |
|
2009 |
Nam JH, Ermonval M, Sharfstein ST. The effects of microcarrier culture on recombinant CHO cells under biphasic hypothermic culture conditions. Cytotechnology. 59: 81-91. PMID 19412658 DOI: 10.1007/S10616-009-9196-X |
0.393 |
|
2009 |
Jiang Z, Sharfstein ST. Characterization of gene localization and accessibility in DHFR-amplified CHO cells. Biotechnology Progress. 25: 296-300. PMID 19224609 DOI: 10.1002/Btpr.82 |
0.375 |
|
2008 |
Nam JH, Zhang F, Ermonval M, Linhardt RJ, Sharfstein ST. The effects of culture conditions on the glycosylation of secreted human placental alkaline phosphatase produced in Chinese hamster ovary cells Biotechnology and Bioengineering. 100: 1178-1192. PMID 18553404 DOI: 10.1002/Bit.21853 |
0.37 |
|
2008 |
Sharfstein ST. Advances in cell culture process development: Tools and techniques for improving cell line development and process optimization Biotechnology Progress. 24: 727-734. PMID 18426245 DOI: 10.1021/Bp070471Q |
0.445 |
|
2008 |
Jiang Z, Sharfstein ST. Sodium butyrate stimulates monoclonal antibody over-expression in CHO cells by improving gene accessibility. Biotechnology and Bioengineering. 100: 189-94. PMID 18023047 DOI: 10.1002/Bit.21726 |
0.421 |
|
2007 |
Jong HN, Ermonval M, Sharfstein ST. Cell attachment to microcarriers affects growth, metabolic activity, and culture productivity in bioreactor culture Biotechnology Progress. 23: 652-660. PMID 17500530 DOI: 10.1021/Bp070007L |
0.406 |
|
2007 |
Venkiteshwaran A, Heider P, Matosevic S, Bogsnes A, Staby A, Sharfstein S, Belfort G. Optimized removal of soluble host cell proteins for the recovery of met-human growth hormone inclusion bodies from Escherichia coli cell lysate using crossflow microfiltration Biotechnology Progress. 23: 667-672. PMID 17480055 DOI: 10.1021/Bp0700253 |
0.337 |
|
2006 |
Jiang Z, Huang Y, Sharfstein ST. Regulation of recombinant monoclonal antibody production in Chinese hamster ovary cells: A comparative study of gene copy number, mRNA level, and protein expression Biotechnology Progress. 22: 313-318. PMID 16454525 DOI: 10.1021/Bp0501524 |
0.426 |
|
2006 |
Shen D, Sharfstein ST. Genome-wide analysis of the transcriptional response of murine hybridomas to osmotic shock Biotechnology and Bioengineering. 93: 132-145. PMID 16196057 DOI: 10.1002/Bit.20691 |
0.348 |
|
2005 |
McNeeley KM, Sun Z, Sharfstein ST. Techniques for dual staining of DNA and intracellular immunoglobulins in murine hybridoma cells: applications to cell-cycle analysis of hyperosmotic cultures. Cytotechnology. 48: 15-26. PMID 19003029 DOI: 10.1007/S10616-005-2926-9 |
0.373 |
|
2004 |
Sun Z, Zhou R, Liang S, McNeeley KM, Sharfstein ST. Hyperosmotic stress in murine hybridoma cells: effects on antibody transcription, translation, posttranslational processing, and the cell cycle. Biotechnology Progress. 20: 576-89. PMID 15059005 DOI: 10.1021/Bp0342203 |
0.382 |
|
1998 |
Mancuso A, Sharfstein ST, Fernandez EJ, Clark DS, Blanch HW. Effect of extracellular glutamine concentration on primary and secondary metabolism of a murine hybridoma: an in vivo 13C nuclear magnetic resonance study. Biotechnology and Bioengineering. 57: 172-86. PMID 10099192 DOI: 10.1002/(Sici)1097-0290(19980120)57:2<172::Aid-Bit6>3.0.Co;2-K |
0.676 |
|
1994 |
Mancuso A, Sharfstein ST, Tucker SN, Clark DS, Blanch HW. Examination of primary metabolic pathways in a murine hybridoma with carbon-13 nuclear magnetic resonance spectroscopy. Biotechnology and Bioengineering. 44: 563-85. PMID 18618793 DOI: 10.1002/Bit.260440504 |
0.523 |
|
1994 |
Sharfstein ST, Tucker SN, Mancuso A, Blanch HW, Clark DS. Quantitative in vivo nuclear magnetic resonance studies of hybridoma metabolism. Biotechnology and Bioengineering. 43: 1059-74. PMID 18615517 DOI: 10.1002/Bit.260431109 |
0.545 |
|
1994 |
Sharfstein ST, Keasling JD. Polyphosphate metabolism in escherichia coli Annals of the New York Academy of Sciences. 745: 77-91. PMID 7832534 DOI: 10.1111/J.1749-6632.1994.Tb44365.X |
0.307 |
|
1992 |
Sharfstein ST, Gaillard B, Blanch HW, Clark DS. Functional differentiation and primary metabolism of mouse mammary epithelial cells in extended-batch and hollow-fiber culture. Biotechnology and Bioengineering. 40: 672-80. PMID 18601166 DOI: 10.1002/Bit.260400605 |
0.563 |
|
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