| Year |
Citation |
Score |
| 2018 |
Liu X, Xie F, Doughty LB, Wang Q, Zhang L, Liu X, Cheng YQ. Genomics-guided discovery of a new and significantly better source of anticancer natural drug FK228. Synthetic and Systems Biotechnology. 3: 268-274. PMID 30417143 DOI: 10.1016/J.Synbio.2018.10.011 |
0.354 |
|
| 2018 |
Qiao Y, Tong T, Xue J, Lin W, Deng Z, Cheng YQ, Zhu D. Mechanistic studies of DepR in regulating FK228 biosynthesis in Chromobacterium violaceum no. 968. Plos One. 13: e0196173. PMID 29672625 DOI: 10.1371/Journal.Pone.0196173 |
0.33 |
|
| 2015 |
Shah GR, Wesener SR, Cheng YQ. Engineered Production of Tryprostatins in E. coli through Reconstitution of a Partial ftm Biosynthetic Gene Cluster from Aspergillus sp. Jacobs Journal of Biotechnology and Bioengineering. 2. PMID 26640821 |
0.767 |
|
| 2015 |
Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, ... ... Cheng YQ, et al. Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology. 11: 625-31. PMID 26284661 DOI: 10.1038/Nchembio.1890 |
0.466 |
|
| 2014 |
Potharla VY, Wang C, Cheng YQ. Identification and characterization of the spiruchostatin biosynthetic gene cluster enable yield improvement by overexpressing a transcriptional activator. Journal of Industrial Microbiology & Biotechnology. 41: 1457-65. PMID 24973954 DOI: 10.1007/S10295-014-1474-8 |
0.766 |
|
| 2014 |
Liu X, Cheng YQ. Genome-guided discovery of diverse natural products from Burkholderia sp. Journal of Industrial Microbiology & Biotechnology. 41: 275-84. PMID 24212473 DOI: 10.1007/s10295-013-1376-1 |
0.399 |
|
| 2013 |
Liu X, Biswas S, Berg MG, Antapli CM, Xie F, Wang Q, Tang MC, Tang GL, Zhang L, Dreyfuss G, Cheng YQ. Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43. Journal of Natural Products. 76: 685-93. PMID 23517093 DOI: 10.1021/Np300913H |
0.361 |
|
| 2012 |
Shah GR, Wesener S, Cheng Y. Abstract 4646: Toward engineering of novel anticancer bio-agents Cancer Research. 72: 4646-4646. DOI: 10.1158/1538-7445.Am2012-4646 |
0.681 |
|
| 2011 |
Wesener SR, Potharla VY, Cheng YQ. Reconstitution of the FK228 biosynthetic pathway reveals cross talk between modular polyketide synthases and fatty acid synthase. Applied and Environmental Microbiology. 77: 1501-7. PMID 21183648 DOI: 10.1128/Aem.01513-10 |
0.656 |
|
| 2011 |
Potharla VY, Wesener SR, Cheng YQ. New insights into the genetic organization of the FK228 biosynthetic gene cluster in Chromobacterium violaceum no. 968. Applied and Environmental Microbiology. 77: 1508-11. PMID 21183645 DOI: 10.1128/Aem.01512-10 |
0.647 |
|
| 2009 |
Matter AM, Hoot SB, Anderson PD, Neves SS, Cheng YQ. Valinomycin biosynthetic gene cluster in Streptomyces: conservation, ecology and evolution. Plos One. 4: e7194. PMID 19787052 DOI: 10.1371/Journal.Pone.0007194 |
0.62 |
|
| 2009 |
Wang C, Wesener SR, Zhang H, Cheng YQ. An FAD-dependent pyridine nucleotide-disulfide oxidoreductase is involved in disulfide bond formation in FK228 anticancer depsipeptide. Chemistry & Biology. 16: 585-93. PMID 19549597 DOI: 10.1016/J.Chembiol.2009.05.005 |
0.71 |
|
| 2007 |
Cheng YQ, Yang M, Matter AM. Characterization of a gene cluster responsible for the biosynthesis of anticancer agent FK228 in Chromobacterium violaceum No. 968. Applied and Environmental Microbiology. 73: 3460-9. PMID 17400765 DOI: 10.1128/Aem.01751-06 |
0.635 |
|
| 2006 |
Tang GL, Cheng YQ, Shen B. Polyketide chain skipping mechanism in the biosynthesis of the hybrid nonribosomal peptide-polyketide antitumor antibiotic leinamycin in Streptomyces atroolivaceus S-140. Journal of Natural Products. 69: 387-93. PMID 16562841 DOI: 10.1021/Np050467T |
0.303 |
|
| 2006 |
Cheng YQ. Deciphering the biosynthetic codes for the potent anti-SARS-CoV cyclodepsipeptide valinomycin in Streptomyces tsusimaensis ATCC 15141. Chembiochem : a European Journal of Chemical Biology. 7: 471-7. PMID 16511823 DOI: 10.1002/cbic.200500425 |
0.399 |
|
| 2004 |
Tang GL, Cheng YQ, Shen B. Leinamycin biosynthesis revealing unprecedented architectural complexity for a hybrid polyketide synthase and nonribosomal peptide synthetase. Chemistry & Biology. 11: 33-45. PMID 15112993 DOI: 10.1016/J.Chembiol.2003.12.014 |
0.39 |
|
| 2003 |
Cheng YQ, Tang GL, Shen B. Type I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 100: 3149-54. PMID 12598647 DOI: 10.1073/Pnas.0537286100 |
0.46 |
|
| 2002 |
Cheng YQ, Tang GL, Shen B. Identification and localization of the gene cluster encoding biosynthesis of the antitumor macrolactam leinamycin in Streptomyces atroolivaceus S-140. Journal of Bacteriology. 184: 7013-24. PMID 12446651 DOI: 10.1128/Jb.184.24.7013-7024.2002 |
0.493 |
|
| 2002 |
Ahn JH, Cheng YQ, Walton JD. An extended physical map of the TOX2 locus of Cochliobolus carbonum required for biosynthesis of HC-toxin. Fungal Genetics and Biology : Fg & B. 35: 31-8. PMID 11860263 DOI: 10.1006/fgbi.2001.1305 |
0.382 |
|
| 1999 |
Cheng YQ, Ahn JH, Walton JD. A putative branched-chain-amino-acid transaminase gene required for HC-toxin biosynthesis and pathogenicity in Cochliobolus carbonum. Microbiology (Reading, England). 145: 3539-46. PMID 10627051 DOI: 10.1099/00221287-145-12-3539 |
0.347 |
|
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