Ryszard Kole - Publications

Affiliations: 
Pharmacology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Molecular Biology, Biochemistry, Oncology

81 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Nualkaew T, Jearawiriyapaisarn N, Hongeng S, Fucharoen S, Kole R, Svasti S. Restoration of correct β-globin mRNA splicing and HbA production by engineered U7 snRNA in β-thalassaemia/HbE erythroid cells. Scientific Reports. 9: 7672. PMID 31113996 DOI: 10.1038/S41598-019-43964-3  0.361
2018 Preedagasamzin S, Nualkaew T, Pongrujikorn T, Jinawath N, Kole R, Fucharoen S, Jearawiriyapaisarn N, Svasti S. Engineered U7 snRNA mediates sustained splicing correction in erythroid cells from β-thalassemia/HbE patients. Biochemical and Biophysical Research Communications. PMID 29550480 DOI: 10.1016/J.Bbrc.2018.03.102  0.401
2017 Echigoya Y, Nakamura A, Nagata T, Urasawa N, Lim KR, Trieu N, Panesar D, Kuraoka M, Moulton HM, Saito T, Aoki Y, Iversen P, Sazani P, Kole R, Maruyama R, et al. Effects of systemic multiexon skipping with peptide-conjugated morpholinos in the heart of a dog model of Duchenne muscular dystrophy. Proceedings of the National Academy of Sciences of the United States of America. PMID 28373570 DOI: 10.1073/Pnas.1613203114  0.672
2016 Chiper M, Tounsi N, Kole R, Kichler A, Zuber G. Self-aggregating 1.8 kDa polyethylenimines with dissolution switch at endosomal acidic pH are delivery carriers for plasmid DNA, mRNA, siRNA and exon-skipping oligonucleotides. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27956144 DOI: 10.1016/J.Jconrel.2016.12.005  0.334
2013 Wan J, Bauman JA, Graziewicz MA, Sazani P, Kole R. Oligonucleotide therapeutics in cancer. Cancer Treatment and Research. 158: 213-33. PMID 24222360 DOI: 10.1007/978-3-642-31659-3_9  0.744
2013 Kole R. Splicing: hear and now! Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 920-1. PMID 23636290 DOI: 10.1038/Mt.2013.75  0.471
2013 Wan J, Bauman JA, Graziewicz MA, Sazani P, Kole R. Oligonucleotide therapeutics in cancer Cancer Treatment and Research. 158: 213-233. DOI: 10.1007/978-3-642-31659-3_9  0.657
2012 Fletcher S, Adkin CF, Meloni P, Wong B, Muntoni F, Kole R, Fragall C, Greer K, Johnsen R, Wilton SD. Targeted exon skipping to address "leaky" mutations in the dystrophin gene. Molecular Therapy. Nucleic Acids. 1: e48. PMID 23344648 DOI: 10.1038/mtna.2012.40  0.318
2012 Kole R, Leppert BJ. Targeting mRNA splicing as a potential treatment for Duchenne muscular dystrophy. Discovery Medicine. 14: 59-69. PMID 22846203  0.332
2012 Kole R, Krainer AR, Altman S. RNA therapeutics: beyond RNA interference and antisense oligonucleotides. Nature Reviews. Drug Discovery. 11: 125-40. PMID 22262036 DOI: 10.1038/Nrd3625  0.345
2011 Bauman JA, Kole R. Modulation of RNA splicing as a potential treatment for cancer. Bioengineered Bugs. 2: 125-8. PMID 21637003 DOI: 10.4161/Bbug.2.3.15165  0.528
2010 Bauman JA, Li SD, Yang A, Huang L, Kole R. Anti-tumor activity of splice-switching oligonucleotides. Nucleic Acids Research. 38: 8348-56. PMID 20719743 DOI: 10.1093/Nar/Gkq731  0.401
2010 Jearawiriyapaisarn N, Moulton HM, Sazani P, Kole R, Willis MS. Long-term improvement in mdx cardiomyopathy after therapy with peptide-conjugated morpholino oligomers. Cardiovascular Research. 85: 444-53. PMID 19815563 DOI: 10.1093/Cvr/Cvp335  0.667
2009 Moulton HM, Wu B, Jearawiriyapaisarn N, Sazani P, Lu QL, Kole R. Peptide-morpholino conjugate: a promising therapeutic for Duchenne muscular dystrophy. Annals of the New York Academy of Sciences. 1175: 55-60. PMID 19796077 DOI: 10.1111/J.1749-6632.2009.04976.X  0.643
2009 Kinali M, Arechavala-Gomeza V, Feng L, Cirak S, Hunt D, Adkin C, Guglieri M, Ashton E, Abbs S, Nihoyannopoulos P, Garralda ME, Rutherford M, McCulley C, Popplewell L, Graham IR, ... Kole R, et al. Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept study. The Lancet. Neurology. 8: 918-28. PMID 19713152 DOI: 10.1016/S1474-4422(09)70211-X  0.333
2009 Lonkar P, Kim KH, Kuan JY, Chin JY, Rogers FA, Knauert MP, Kole R, Nielsen PE, Glazer PM. Targeted correction of a thalassemia-associated beta-globin mutation induced by pseudo-complementary peptide nucleic acids. Nucleic Acids Research. 37: 3635-44. PMID 19364810 DOI: 10.1093/Nar/Gkp217  0.413
2009 Svasti S, Suwanmanee T, Fucharoen S, Moulton HM, Nelson MH, Maeda N, Smithies O, Kole R. RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 1205-10. PMID 19164558 DOI: 10.1073/Pnas.0812436106  0.457
2009 Bauman J, Jearawiriyapaisarn N, Kole R. Therapeutic potential of splice-switching oligonucleotides. Oligonucleotides. 19: 1-13. PMID 19125639 DOI: 10.1089/Oli.2008.0161  0.481
2009 Wan J, Sazani P, Kole R. Modification of HER2 pre-mRNA alternative splicing and its effects on breast cancer cells. International Journal of Cancer. Journal International Du Cancer. 124: 772-7. PMID 19035464 DOI: 10.1002/Ijc.24052  0.739
2008 Graziewicz MA, Tarrant TK, Buckley B, Roberts J, Fulton L, Hansen H, Ørum H, Kole R, Sazani P. An Endogenous TNF-α Antagonist Induced by Splice-switching Oligonucleotides Reduces Inflammation in Hepatitis and Arthritis Mouse Models. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1316-1322. PMID 28178484 DOI: 10.1038/Mt.2008.85  0.679
2008 Chin JY, Kuan JY, Lonkar PS, Krause DS, Seidman MM, Peterson KR, Nielsen PE, Kole R, Glazer PM. Correction of a splice-site mutation in the beta-globin gene stimulated by triplex-forming peptide nucleic acids. Proceedings of the National Academy of Sciences of the United States of America. 105: 13514-9. PMID 18757759 DOI: 10.1073/Pnas.0711793105  0.404
2008 Jearawiriyapaisarn N, Moulton HM, Buckley B, Roberts J, Sazani P, Fucharoen S, Iversen PL, Kole R. Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1624-9. PMID 18545222 DOI: 10.1038/Mt.2008.120  0.709
2008 Graziewicz MA, Tarrant TK, Buckley B, Roberts J, Fulton L, Hansen H, Ørum H, Kole R, Sazani P. An endogenous TNF-alpha antagonist induced by splice-switching oligonucleotides reduces inflammation in hepatitis and arthritis mouse models. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1316-22. PMID 18461057 DOI: 10.1038/mt.2008.85  0.652
2007 Resina S, Kole R, Travo A, Lebleu B, Thierry AR. Switching on transgene expression by correcting aberrant splicing using multi-targeting steric-blocking oligonucleotides. The Journal of Gene Medicine. 9: 498-510. PMID 17471591 DOI: 10.1002/Jgm.1044  0.439
2006 Roberts J, Palma E, Sazani P, Ørum H, Cho M, Kole R. Efficient and persistent splice switching by systemically delivered LNA oligonucleotides in mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 471-5. PMID 16854630 DOI: 10.1016/J.Ymthe.2006.05.017  0.717
2006 Williams T, Kole R. Analysis of prostate-specific membrane antigen splice variants in LNCap cells. Oligonucleotides. 16: 186-95. PMID 16764542 DOI: 10.1089/Oli.2006.16.186  0.568
2006 Kuan JY, Kole R, Nielsen PE, Glazer PM. 89. Gene Targeting of β_Globin IVS2 Using Sequence_Specific Peptide Nucleic Acids Molecular Therapy. 13: S37. DOI: 10.1016/J.Ymthe.2006.08.107  0.419
2005 Suwanmanee T, Choi VW, Samulski RJ, Kafri T, Kole R. 343. Repair of Thalassemic |[beta]|-Globin pre-mRNA by Antisense AAV and Lentiviral Vectors in Cell Culture Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.346  0.46
2005 Williams TL, Kole R. 321. Splice-Switching of the Prostate Specific Membrane Antigen (PSMA) in LnCap Prostate Cancer Cells Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.324  0.596
2004 Kole R, Williams T, Cohen L. RNA modulation, repair and remodeling by splice switching oligonucleotides. Acta Biochimica Polonica. 51: 373-8. PMID 15218534 DOI: 10.18388/Abp.2004_3576  0.664
2004 Kole R, Vacek M, Williams T. Modification of alternative splicing by antisense therapeutics. Oligonucleotides. 14: 65-74. PMID 15104897 DOI: 10.1089/154545704322988067  0.796
2004 Asparuhova M, Kole R, Schumperli D. Antisense derivatives of U7 and other small nuclear RNAs as tools to modify pre-mRNA splicing patterns Gene Therapy and Regulation. 2: 321-349. DOI: 10.1163/1568558043967472  0.456
2003 Sazani P, Astriab-Fischer A, Kole R. Effects of base modifications on antisense properties of 2'-O-methoxyethyl and PNA oligonucleotides. Antisense & Nucleic Acid Drug Development. 13: 119-28. PMID 12954112 DOI: 10.1089/108729003768247583  0.702
2003 Bristow CL, Mercatante DR, Kole R. HIV-1 preferentially binds receptors copatched with cell-surface elastase. Blood. 102: 4479-86. PMID 12933574 DOI: 10.1182/Blood-2003-05-1635  0.737
2003 Sazani P, Kole R. Therapeutic potential of antisense oligonucleotides as modulators of alternative splicing. The Journal of Clinical Investigation. 112: 481-6. PMID 12925686 DOI: 10.1172/Jci19547  0.743
2003 Vacek M, Sazani P, Kole R. Antisense-mediated redirection of mRNA splicing Cellular and Molecular Life Sciences. 60: 825-833. PMID 12827272 DOI: 10.1007/S00018-003-3042-7  0.784
2003 Ghio AJ, Nozik-Grayck E, Turi J, Jaspers I, Mercatante DR, Kole R, Piantadosi CA. Superoxide-dependent iron uptake: a new role for anion exchange protein 2. American Journal of Respiratory Cell and Molecular Biology. 29: 653-60. PMID 12791678 DOI: 10.1165/Rcmb.2003-0070Oc  0.742
2003 Vacek MM, Ma H, Gemignani F, Lacerra G, Kafri T, Kole R. High-level expression of hemoglobin A in human thalassemic erythroid progenitor cells following lentiviral vector delivery of an antisense snRNA. Blood. 101: 104-11. PMID 12393543 DOI: 10.1182/Blood-2002-06-1869  0.791
2002 Suwanmanee T, Sierakowska H, Fucharoen S, Kole R. Repair of a splicing defect in erythroid cells from patients with beta-thalassemia/HbE disorder. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 718-26. PMID 12498768 DOI: 10.1006/Mthe.2002.0805  0.371
2002 Sazani P, Vacek MM, Kole R. Short-term and long-term modulation of gene expression by antisense therapeutics. Current Opinion in Biotechnology. 13: 468-72. PMID 12459339 DOI: 10.1016/S0958-1669(02)00366-X  0.763
2002 Sazani P, Gemignani F, Kang SH, Maier MA, Manoharan M, Persmark M, Bortner D, Kole R. Systemically delivered antisense oligomers upregulate gene expression in mouse tissues. Nature Biotechnology. 20: 1228-33. PMID 12426578 DOI: 10.1038/Nbt759  0.729
2002 Gemignani F, Sazani P, Morcos P, Kole R. Temperature-dependent splicing of beta-globin pre-mRNA. Nucleic Acids Research. 30: 4592-8. PMID 12409448 DOI: 10.1093/Nar/Gkf607  0.721
2002 Mercatante DR, Mohler JL, Kole R. Cellular response to an antisense-mediated shift of Bcl-x pre-mRNA splicing and antineoplastic agents. The Journal of Biological Chemistry. 277: 49374-82. PMID 12381725 DOI: 10.1074/Jbc.M209236200  0.78
2002 Suwanmanee T, Sierakowska H, Lacerra G, Svasti S, Kirby S, Walsh CE, Fucharoen S, Kole R. Restoration of human beta-globin gene expression in murine and human IVS2-654 thalassemic erythroid cells by free uptake of antisense oligonucleotides. Molecular Pharmacology. 62: 545-53. PMID 12181431 DOI: 10.1124/Mol.62.3.545  0.428
2002 Mercatante DR, Kole R. Control of alternative splicing by antisense oligonucleotides as a potential chemotherapy: effects on gene expression. Biochimica Et Biophysica Acta. 1587: 126-32. PMID 12084454 DOI: 10.1016/S0925-4439(02)00075-3  0.808
2001 Mercatante DR, Sazani P, Kole R. Modification of alternative splicing by antisense oligonucleotides as a potential chemotherapy for cancer and other diseases. Current Cancer Drug Targets. 1: 211-30. PMID 12188880  0.798
2001 Gemignani F, Landi S, De David M, Kole R. Spontaneous and MNNG-induced reversion of an EGFP construct in HeLa cells: An assay for observing mutations in living cells by fluorescent microscopy Human Mutation. 18: 526-534. PMID 11748845 DOI: 10.1002/Humu.1229  0.334
2001 Sazani P, Kang SH, Maier MA, Wei C, Dillman J, Summerton J, Manoharan M, Kole R. Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs Nucleic Acids Research. 29: 3965-3974. PMID 11574678 DOI: 10.1093/Nar/29.19.3965  0.699
2001 Tian H, Kole R. Strong RNA Splicing Enhancers Identified by a Modified Method of Cycled Selection Interact with SR Protein Journal of Biological Chemistry. 276: 33833-33839. PMID 11454855 DOI: 10.1074/Jbc.M102957200  0.405
2001 Mercatante DR, Bortner CD, Cidlowski JA, Kole R. Modification of alternative splicing of Bcl-x pre-mRNA in prostate and breast cancer cells. analysis of apoptosis and cell death. The Journal of Biological Chemistry. 276: 16411-7. PMID 11278482 DOI: 10.1074/Jbc.M009256200  0.789
2000 Gorman L, Mercatante DR, Kole R. Restoration of correct splicing of thalassemic beta-globin pre-mRNA by modified U1 snRNAs. The Journal of Biological Chemistry. 275: 35914-9. PMID 10969081 DOI: 10.1074/Jbc.M006259200  0.798
2000 Lacerra G, Sierakowska H, Carestia C, Fucharoen S, Summerton J, Weller D, Kole R. Restoration of hemoglobin A synthesis in erythroid cells from peripheral blood of thalassemic patients Proceedings of the National Academy of Sciences of the United States of America. 97: 9591-9596. PMID 10944225 DOI: 10.1073/Pnas.97.17.9591  0.383
2000 Mercatante D, Kole R. Modification of alternative splicing pathways as a potential approach to chemotherapy Pharmacology and Therapeutics. 85: 237-243. PMID 10739878 DOI: 10.1016/S0163-7258(99)00067-4  0.804
2000 Sierakowska H, Gorman L, Kang SH, Kole R. Antisense oligonucleotides and RNAs as modulators of pre-mRNA splicing Methods in Enzymology. 313: 506-521. PMID 10595376 DOI: 10.1016/S0076-6879(00)13032-0  0.515
2000 Sierakowska H, Agrawal S, Kole R. Antisense oligonucleotides as modulators of pre-mRNA splicing Methods in Molecular Biology (Clifton, N.J.). 133: 223-233. PMID 10561842 DOI: 10.1385/1-59259-215-5:223  0.398
1999 Kang SH, Zirbes EL, Kole R. Delivery of antisense oligonucleotides and plasmid DNA with various carrier agents Antisense and Nucleic Acid Drug Development. 9: 497-505. PMID 10645775 DOI: 10.1089/Oli.1.1999.9.497  0.301
1999 Friedman KJ, Kole J, Cohn JA, Knowles MR, Silverman LM, Kole R. Correction of aberrant splicing of the cystic fibrosis transmembrane conductance regulator (CFTR) gene by antisense oligonucleotides Journal of Biological Chemistry. 274: 36193-36199. PMID 10593905 DOI: 10.1074/Jbc.274.51.36193  0.442
1999 Suter D, Tomasini R, Reber U, Gorman L, Kole R, Schümperli D. Double-target antisense U7 snRNAs promote efficient skipping of an aberrant exon in three human β-thalassemic mutations Human Molecular Genetics. 8: 2415-2423. PMID 10556289 DOI: 10.1093/Hmg/8.13.2415  0.432
1999 DeLong RK, Yoo H, Alahari SK, Fisher M, Short SM, Kang SH, Kole R, Janout V, Regan SL, Juliano RL. Novel cationic amphiphiles as delivery agents for antisense oligonucleotides. Nucleic Acids Research. 27: 3334-41. PMID 10454641 DOI: 10.1093/Nar/27.16.3334  0.328
1999 Schmajuk G, Sierakowska H, Kole R. Antisense oligonucleotides with different backbones. Modification of splicing pathways and efficacy of uptake Journal of Biological Chemistry. 274: 21783-21789. PMID 10419493 DOI: 10.1074/Jbc.274.31.21783  0.372
1999 Wilton SD, Lloyd F, Carville K, Fletcher S, Honeyman K, Agrawal S, Kole R. Specific removal of the nonsense mutation from the mdx dystrophin mRNA using antisense oligonucleotides Neuromuscular Disorders. 9: 330-338. PMID 10407856 DOI: 10.1016/S0960-8966(99)00010-3  0.466
1999 Sierakowska H, Sambade MJ, Schümperli D, Kole R. Sensitivity of splice sites to antisense oligonucleotides in vivo Rna. 5: 369-377. PMID 10094306 DOI: 10.1017/S135583829998130X  0.427
1998 Westphal EM, Sierakowska H, Livanos E, Kole R, Vos JM. A system for shuttling 200-kb BAC/PAC clones into human cells: Stable extrachromosomal persistence and long-term ectopic gene activation Human Gene Therapy. 9: 1863-1873. PMID 9741425 DOI: 10.1089/Hum.1998.9.13-1863  0.349
1998 Kang SH, Cho MJ, Kole R. Up-regulation of luciferase gene expression with antisense oligonucleotides: Implications and applications in functional assay development Biochemistry. 37: 6235-6239. PMID 9572837 DOI: 10.1021/Bi980300H  0.474
1998 Gorman L, Suter D, Emerick V, Schümperli D, Kole R. Stable alteration of pre-mRNA splicing patterns by modified U7 small nuclear RNAs Proceedings of the National Academy of Sciences of the United States of America. 95: 4929-4934. PMID 9560205 DOI: 10.1073/Pnas.95.9.4929  0.45
1998 Lewis J, Yang B, Kim R, Sierakowska H, Kole R, Smithies O, Maeda N. A common human beta globin splicing mutation modeled in mice. Blood. 91: 2152-6. PMID 9490703 DOI: 10.1182/Blood.V91.6.2152.2152_2152_2156  0.383
1997 Kole R. Modification of pre-mRNA splicing by antisense oligonucleotides. Acta Biochimica Polonica. 44: 231-237. DOI: 10.18388/Abp.1997_4418  0.46
1997 Sierakowska H, Montague M, Agrawal S, Kole R. Restoration of ß-Globin Gene Expression in Mammalian Cells by Antisense Oligonucleotides That Modify the Aberrant Splicing Patierns of Thalassemic Pre-mRNAs Nucleosides, Nucleotides & Nucleic Acids. 16: 1173-1182. DOI: 10.1080/07328319708006154  0.483
1996 Sierakowska H, Sambade MJ, Agrawal S, Kole R. Repair of thalassemic human β-globin mRNA in mammalian cells by antisense oligonucleotides Proceedings of the National Academy of Sciences of the United States of America. 93: 12840-12844. PMID 8917506 DOI: 10.1073/Pnas.93.23.12840  0.411
1996 Dominski Z, Kole R. Effects of exon sequences on splicing of model pre-mRNA substrates in vitro Acta Biochimica Polonica. 43: 161-174. PMID 8790721 DOI: 10.18388/Abp.1996_4574  0.389
1996 Dominski Z, Ferree P, Kole R. Antisense 2′-O-methyloligoribonucleotides hybridized to RNA block a nuclear, ATP-dependent 3′-5′ exonuclease Antisense and Nucleic Acid Drug Development. 6: 37-45. PMID 8783794 DOI: 10.1089/Oli.1.1996.6.37  0.368
1995 Tian H, Kole R. Selection of novel exon recognition elements from a pool of random sequences Molecular and Cellular Biology. 15: 6291-6298. PMID 7565782 DOI: 10.1128/Mcb.15.11.6291  0.378
1994 Dominski Z, Kole R. Identification and characterization by antisense oligonucleotides of exon and intron sequences required for splicing Molecular and Cellular Biology. 14: 7445-7454. PMID 7935459 DOI: 10.1128/Mcb.14.11.7445  0.381
1993 Dominski Z, Kole R. Restoration of correct splicing in thalassemic pre-mRNA by antisense oligonucleotides Proceedings of the National Academy of Sciences of the United States of America. 90: 8673-8677. PMID 8378346 DOI: 10.1073/Pnas.90.18.8673  0.444
1992 Dominski Z, Kole R. Cooperation of pre-mRNA sequence elements in splice site selection Molecular and Cellular Biology. 12: 2108-2114. PMID 1569943 DOI: 10.1128/Mcb.12.5.2108  0.423
1991 Dominski Z, Kole R. Selection of Splice Sites in Pre-mRNAs with Short Internal Exons Molecular and Cellular Biology. 11: 6075-6083. PMID 1944277 DOI: 10.1128/Mcb.11.12.6075  0.455
1989 Furdon PJ, Dominski Z, Kole R. RNase H cleavage of RNA hybridized to oligonucleotides containing methylphosphonate, phosphorothioate and phosphodiester bonds Nucleic Acids Research. 17: 9193-9204. PMID 2555787 DOI: 10.1093/Nar/17.22.9193  0.342
1988 Furdon PJ, Kole R. The length of the downstream exon and the substitution of specific sequences affect pre-mRNA splicing in vitro Molecular and Cellular Biology. 8: 860-866. PMID 3352607 DOI: 10.1128/Mcb.8.2.860  0.415
1987 Furdon PJ, Kole R. RNA fingerprinting using a small horizontal agarose gel electrophoresis apparatus Analytical Biochemistry. 162: 74-79. PMID 2440342 DOI: 10.1016/0003-2697(87)90011-X  0.346
1986 Sierakowska H, Szer W, Furdon PJ, Kole R. Antibodies to hnRNP core proteins inhibit in vitro splicing of human β-globin pre-mRNA Nucleic Acids Research. 14: 5241-5254. PMID 3737400 DOI: 10.1093/Nar/14.13.5241  0.377
1986 Furdon PJ, Kole R. Inhibition of splicing but not cleavage at the 5' splice site by truncating human β-globin pre-mRNA Proceedings of the National Academy of Sciences of the United States of America. 83: 927-931. PMID 2937057 DOI: 10.1073/Pnas.83.4.927  0.402
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