Manohar Ratnam - Publications

Affiliations: 
College of Medicine The University of Toledo 
Area:
Molecular Biology, Biochemistry, Oncology
Website:
https://cancerbiologyprogram.med.wayne.edu/profile/ea3489

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Soave C, Ducker C, Kim S, Strahl T, Rosati R, Huang Y, Shaw P, Ratnam M. Identification of ELK1 interacting peptide segments in the androgen receptor. The Biochemical Journal. PMID 35781489 DOI: 10.1042/BCJ20220297  0.379
2020 Rosati R, Oppat K, Huang Y, Kim S, Ratnam M. Clinical association of progesterone receptor isoform A with breast cancer metastasis consistent with its unique mechanistic role in preclinical models. Bmc Cancer. 20: 512. PMID 32493230 DOI: 10.1186/s12885-020-07002-0  0.308
2019 Pardy L, Rosati R, Soave C, Huang Y, Kim S, Ratnam M. The ternary complex factor protein ELK1 is an independent prognosticator of disease recurrence in prostate cancer. The Prostate. PMID 31794091 DOI: 10.1002/pros.23932  0.385
2018 Patki M, McFall T, Rosati R, Huang Y, Malysa A, Polin L, Fielder A, Wilson MR, Lonardo F, Back J, Li J, Matherly LH, Bepler G, Ratnam M. Chronic p27 Induction by Dexamethasone Causes Senescence Phenotype and Permanent Cell Cycle Blockade in Lung Adenocarcinoma Cells Over-expressing Glucocorticoid Receptor. Scientific Reports. 8: 16006. PMID 30375484 DOI: 10.1038/S41598-018-34475-8  0.735
2018 Rosati R, Polin LA, Ducker C, Li J, Bao X, Selvakumar D, Kim S, Xhabija B, Larsen M, McFall T, Huang Y, Kidder BL, Fribley A, Saxton J, Kakuta H, ... ... Ratnam M, et al. Strategy for Tumor Selective Disruption of Androgen Receptor Function in the Spectrum of Prostate Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30185422 DOI: 10.1158/1078-0432.Ccr-18-0982  0.464
2018 Frontera ED, Khansa RM, Schalk DL, Leakan LE, Guerin-Edbauer TJ, Ratnam M, Gorski DH, Speyer CL. IgA Fc-folate conjugate activates and recruits neutrophils to directly target triple-negative breast cancer cells. Breast Cancer Research and Treatment. PMID 30155754 DOI: 10.1007/s10549-018-4941-5  0.314
2016 Rosati R, Patki M, Chari V, Dakshnamurthy S, McFall T, Saxton J, Kidder BL, Shaw PE, Ratnam M. The Amino-terminal Domain of the Androgen Receptor Co-opts ERK Docking Sites in ELK1 to Induce Sustained Gene Activation that Supports Prostate Cancer Cell Growth. The Journal of Biological Chemistry. PMID 27793987 DOI: 10.1074/Jbc.M116.745596  0.793
2016 Rosati R, Chen B, Patki M, McFall T, Ou S, Heath E, Ratnam M, Qin Z. Hybrid Enzalutamide Derivatives with Histone Deacetylase Inhibitor Activity Decrease HSP90 and the Androgen Receptor Levels and Inhibit Viability in Enzalutamide Resistant C4-2 Prostate Cancer Cells. Molecular Pharmacology. PMID 27382012 DOI: 10.1124/Mol.116.103416  0.77
2016 Patki M, Huang Y, Ratnam M. Restoration of the cellular secretory milieu overrides androgen dependence of in vivo generated castration resistant prostate cancer cells overexpressing the androgen receptor. Biochemical and Biophysical Research Communications. PMID 27179779 DOI: 10.1016/J.Bbrc.2016.05.058  0.807
2015 McFall T, Patki M, Rosati R, Ratnam M. Role of the short isoform of the progesterone receptor in breast cancer cell invasiveness at estrogen and progesterone levels in the pre- and post-menopausal ranges. Oncotarget. 6: 33146-64. PMID 26356672 DOI: 10.18632/Oncotarget.5082  0.752
2015 Patki M, Salazar Md, Trumbly R, Ratnam M. Differential effects of estrogen-dependent transactivation vs. transrepression by the estrogen receptor on invasiveness of HER2 overexpressing breast cancer cells. Biochemical and Biophysical Research Communications. 457: 404-11. PMID 25582774 DOI: 10.1016/J.Bbrc.2015.01.004  0.746
2015 McFall T, Patki M, Rosati R, Ratnam M. Role of the short isoform of the progesterone receptor in breast cancer cell invasiveness at estrogen and progesterone levels in the pre- and post-menopausal ranges Oncotarget. 6: 33146-33164. DOI: 10.18632/oncotarget.5082  0.756
2015 Patki M, D'Alincourt Salazar M, Trumbly R, Ratnam M. Differential effects of estrogen-dependent transactivation vs. transrepression by the estrogen receptor on invasiveness of HER2 overexpressing breast cancer cells Biochemical and Biophysical Research Communications. 457: 404-411. DOI: 10.1016/j.bbrc.2015.01.004  0.761
2014 Patki M, Gadgeel S, Huang Y, McFall T, Shields AF, Matherly LH, Bepler G, Ratnam M. Glucocorticoid receptor status is a principal determinant of variability in the sensitivity of non-small-cell lung cancer cells to pemetrexed Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 519-526. PMID 24736075 DOI: 10.1097/Jto.0000000000000111  0.743
2014 Shen M, Zhang Z, Ratnam M, Dou QP. The interplay of AMP-activated protein kinase and androgen receptor in prostate cancer cells. Journal of Cellular Physiology. 229: 688-95. PMID 24129850 DOI: 10.1002/jcp.24494  0.47
2013 Patki M, Chari V, Sivakumaran S, Gonit M, Trumbly R, Ratnam M. The ETS domain transcription factor ELK1 directs a critical component of growth signaling by the androgen receptor in prostate cancer cells Journal of Biological Chemistry. 288: 11047-11065. PMID 23426362 DOI: 10.1074/Jbc.M112.438473  0.719
2013 Ratnam M, Patki M, Gonit M, Trumbly R. Mechanisms of ARE-independent gene activation by the androgen receptor in prostate cancer cells: Potential targets for better intervention strategies Androgen-Responsive Genes in Prostate Cancer: Regulation, Function and Clinical Applications. 2147483647: 85-100. DOI: 10.1007/978-1-4614-6182-1_6  0.79
2011 Gonit M, Zhang J, d'Alincourt Salazar M, Cui H, Shatnawi A, Trumbly R, Ratnam M. Hormone depletion-insensitivity of prostate cancer cells is supported by the AR without binding to classical response elements Molecular Endocrinology. 25: 621-634. PMID 21330406 DOI: 10.1210/Me.2010-0409  0.836
2011 Salazar MD, Ratnam M, Patki M, Kisovic I, Trumbly R, Iman M. During hormone depletion or tamoxifen treatment of breast cancer cells the estrogen receptor apoprotein supports cell cycling through the retinoic acid receptor α1 apoprotein Breast Cancer Research. 13. PMID 21299862 DOI: 10.1186/Bcr2827  0.76
2010 Sivakumaran S, Zhang J, Kelley KM, Gonit M, Hao H, Ratnam M. Androgen activation of the folate receptor α gene through partial tethering of the androgen receptor by C/EBPα. The Journal of Steroid Biochemistry and Molecular Biology. 122: 333-40. PMID 20817090 DOI: 10.1016/j.jsbmb.2010.08.008  0.741
2010 Zhang J, Gonit M, Salazar MD, Shatnawi A, Shemshedini L, Trumbly R, Ratnam M. C/EBPα redirects androgen receptor signaling through a unique bimodal interaction Oncogene. 29: 723-738. PMID 19901962 DOI: 10.1038/Onc.2009.373  0.826
2009 Elnakat H, Gonit M, Salazar MDA, Zhang J, Basrur V, Gunning W, Kamen B, Ratnam M. Regulation of folate receptor internalization by protein kinase C Biochemistry. 48: 8249-8260. PMID 19639961 DOI: 10.1021/Bi900565T  0.792
2008 Zhang J, Wilkinson JE, Gonit M, Keck R, Selman S, Ratnam M. Expression and sub-cellular localization of the CCAAT/enhancer binding protein α in relation to postnatal development and malignancy of the prostate Prostate. 68: 1206-1214. PMID 18481268 DOI: 10.1002/Pros.20779  0.812
2007 Lu Y, Wu J, Wu J, Gonit M, Yang X, Lee A, Xiang G, Li H, Liu S, Marcucci G, Ratnam M, Lee RJ. Role of formulation composition in folate receptor-targeted liposomal doxorubicin delivery to acute myelogenous leukemia cells. Molecular Pharmaceutics. 4: 707-12. PMID 17708654 DOI: 10.1021/mp070058l  0.765
2007 Blaser BW, Gonit M, Qi H, Shatnawi A, Guimond M, Lee RJ, Ratnam M. Induction of folate receptor type β in a bone marrow engraftment model of acute myelogenous leukemia [22] Leukemia. 21: 2233-2235. PMID 17554378 DOI: 10.1038/Sj.Leu.2404786  0.749
2006 Elnakat H, Ratnam M. Role of folate receptor genes in reproduction and related cancers Frontiers in Bioscience. 11: 506-519. PMID 16146749 DOI: 10.2741/1815  0.37
2005 Tran T, Shatnawi A, Zheng X, Kelley KM, Ratnam M. Enhancement of folate receptor alpha expression in tumor cells through the glucocorticoid receptor: a promising means to improved tumor detection and targeting. Cancer Research. 65: 4431-41. PMID 15899836 DOI: 10.1158/0008-5472.CAN-04-2890  0.315
2004 Elnakat H, Ratnam M. Distribution, functionality and gene regulation of folate receptor isoforms: implications in targeted therapy. Advanced Drug Delivery Reviews. 56: 1067-84. PMID 15094207 DOI: 10.1016/j.addr.2004.01.001  0.305
1987 Lindstrom J, Criado M, Ratnam M, Whiting P, Ralston S, Rivier J, Sarin V, Sargent P. Using monoclonal antibodies to determine the structures of acetylcholine receptors from electric organs, muscles, and neurons Annals of the New York Academy of Sciences. 505: 208-225. PMID 2446548 DOI: 10.1111/J.1749-6632.1987.Tb51293.X  0.407
1986 Ratnam M, Gullick W, Spiess J, Wan K, Criado M, Lindstrom J. Structural heterogeneity of the alpha subunits of the nicotinic acetylcholine receptor in relation to agonist affinity alkylation and antagonist binding. Biochemistry. 25: 4268-75. PMID 3756139 DOI: 10.1021/Bi00363A014  0.43
1986 Ratnam M, Sargent PB, Sarin V, Fox JL, Nguyen DL, Rivier J, Criado M, Lindstrom J. Location of antigenic determinants on primary sequences of subunits of nicotinic acetylcholine receptor by peptide mapping. Biochemistry. 25: 2621-32. PMID 2424498 DOI: 10.1021/Bi00357A051  0.438
1985 Lindstrom J, Hochschwender S, Wan K, Ratnam M, Criado M. Use of monoclonal antibodies in exploring the structure of the acetylcholine receptor Biochemical Society Transactions. 13: 14-16. PMID 3996735 DOI: 10.1042/Bst0130014  0.437
1984 Ratnam M, Lindstrom J. Structural features of the nicotinic acetylcholine receptor revealed by antibodies to synthetic peptides. Biochemical and Biophysical Research Communications. 122: 1225-1233. PMID 6206851 DOI: 10.1016/0006-291X(84)91223-3  0.481
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