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Michael T. Spiotto, Ph.D. - Publications

Affiliations: 
2003 University of Chicago, Chicago, IL 
Area:
Pathology, Oncology, Cell Biology
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Year Citation  Score
2021 Das T, Zhong R, Spiotto MT. Notch Signaling and Human Papillomavirus-Associated Oral Tumorigenesis. Advances in Experimental Medicine and Biology. 1287: 105-122. PMID 33034029 DOI: 10.1007/978-3-030-55031-8_8  0.312
2020 Howard FM, Kochanny S, Koshy M, Spiotto M, Pearson AT. Machine Learning-Guided Adjuvant Treatment of Head and Neck Cancer. Jama Network Open. 3: e2025881. PMID 33211108 DOI: 10.1200/Jco.2020.38.15_Suppl.6567  0.351
2020 Foster CC, Seiwert TY, MacCracken E, Blair EA, Agrawal N, Melotek JM, Portugal L, Brisson RJ, Gooi Z, Spiotto MT, Vokes EE, Haraf DJ. Dose and Volume De-Escalation for Human Papillomavirus-Positive Oropharyngeal Cancer is Associated with Favorable Post-Treatment Functional Outcomes. International Journal of Radiation Oncology, Biology, Physics. PMID 32311416 DOI: 10.1016/J.Ijrobp.2020.04.014  0.371
2020 Böttinger P, Schreiber K, Hyjek E, Krausz T, Spiotto MT, Steiner M, Idel C, Booras H, Beck-Engeser G, Riederer J, Willimsky G, Wolf SP, Karrison T, Jensen E, Weichselbaum RR, et al. Cooperation of genes in HPV16 E6/E7-dependent cervico-vaginal carcinogenesis trackable by endoscopy and independent of exogenous estrogens or carcinogens. Carcinogenesis. PMID 32221533 DOI: 10.1093/Carcin/Bgaa027  0.571
2020 Hasan Y, Furtado L, Tergas A, Lee N, Brooks R, McCall A, Golden D, Jolly S, Fleming G, Morrow M, Kraynyak K, Sylvester A, Arif F, Levin M, Schwartz D, ... ... Spiotto M, et al. A Phase I trial assessing the safety and tolerability of a therapeutic DNA vaccination against HPV16 and HPV18 E6/E7 oncogenes after chemoradiation for cervical cancer. International Journal of Radiation Oncology, Biology, Physics. PMID 32151670 DOI: 10.1016/J.Ijrobp.2020.02.031  0.317
2020 Bao R, Cabay R, David O, Valyi-Nagy K, Macias V, Zhong R, Spiotto M. Spatial evolution of lymph node metastasis in Human Papillomavirus-negative head and neck cancers International Journal of Radiation Oncology*Biology*Physics. 106: 1115. DOI: 10.1016/J.Ijrobp.2019.11.390  0.327
2020 Rosenberg A, Agrawal N, Pearson A, Seiwert T, Gooi Z, Blair E, Spiotto M, Jones M, Haraf D, Vokes E. Low risk HPV associated oropharyngeal squamous cell carcinoma treated with induction chemoimmunotherapy followed by TORS or radiotherapy International Journal of Radiation Oncology*Biology*Physics. 106: 1123. DOI: 10.1016/J.Ijrobp.2019.11.342  0.32
2020 Rooney M, Turchan W, Korpics M, Koshy M, Spiotto M. Treatment patterns and survival outcomes for odontogenic cancers International Journal of Radiation Oncology*Biology*Physics. 106: 1191. DOI: 10.1016/J.Ijrobp.2019.11.098  0.332
2020 Turchan W, Korpics M, Rooney M, Koshy M, Spiotto M. Site of initial metastasis is associated with survival in salivary gland cancers International Journal of Radiation Oncology*Biology*Physics. 106: 1191. DOI: 10.1016/J.Ijrobp.2019.11.097  0.353
2019 Korpics MC, Turchan WT, Rooney MK, Koshy M, Spiotto MT. Patterns of Care and Outcomes of Intensity-Modulated Radiotherapy and 3D Conformal Radiotherapy for Early Stage Glottic Cancer: A National Cancer Database Analysis. Cancers. 11. PMID 31842271 DOI: 10.3390/Cancers11121996  0.367
2019 Ricco N, Flor A, Wolfgeher D, Efimova EV, Ramamurthy A, Appelbe OK, Brinkman J, Truman AW, Spiotto MT, Kron SJ. Mevalonate pathway activity as a determinant of radiation sensitivity in head and neck cancer. Molecular Oncology. PMID 31225926 DOI: 10.1002/1878-0261.12535  0.349
2019 Foster CC, Rusthoven CG, Sher DJ, Feldman L, Pasquinelli M, Spiotto MT, Koshy M. Corrigendum to "Adjuvant chemotherapy following stereotactic body radiotherapy for early stage non-small-cell lung cancer is associated with lower overall survival: A National Cancer Database Analysis" [Lung Cancer, Volume 130 (April) (2019) 162-168]. Lung Cancer (Amsterdam, Netherlands). PMID 31031052 DOI: 10.1016/J.Lungcan.2019.04.011  0.382
2019 Foster CC, Rusthoven CG, Sher DJ, Feldman L, Pasquinelli M, Spiotto MT, Koshy M. Adjuvant chemotherapy following stereotactic body radiotherapy for early stage non-small-cell lung cancer is associated with lower overall: A National Cancer Database Analysis. Lung Cancer (Amsterdam, Netherlands). 130: 162-168. PMID 30885339 DOI: 10.1016/J.Lungcan.2019.02.023  0.392
2019 Foster CC, Sher DJ, Rusthoven CG, Verma V, Spiotto MT, Weichselbaum RR, Koshy M. Overall survival according to immunotherapy and radiation treatment for metastatic non-small-cell lung cancer: a National Cancer Database analysis. Radiation Oncology (London, England). 14: 18. PMID 30691492 DOI: 10.1186/S13014-019-1222-3  0.424
2019 Foster C, Seiwert T, MacCracken E, Blair E, Agrawal N, Melotek J, Portugal L, Brisson R, Gooi Z, Spiotto M, Haraf D, Vokes E. Dose and Volume De-Escalation for HPV-Positive Oropharyngeal Cancer is Associated with Favorable Post-Treatment Functional Outcomes International Journal of Radiation Oncology*Biology*Physics. 105: E419. DOI: 10.1016/J.Ijrobp.2019.06.1526  0.336
2019 Foster C, Sher D, Rusthoven C, Verma V, Spiotto M, Weichselbaum R, Koshy M. Overall Survival According to Systemic and Radiation Treatment Approaches in Metastatic Non-Small-Cell Lung Cancer: A National Cancer Database Analysis International Journal of Radiation Oncology*Biology*Physics. 104: 244. DOI: 10.1016/J.Ijrobp.2019.01.045  0.389
2018 Lu K, He C, Guo N, Chan C, Ni K, Lan G, Tang H, Pelizzari C, Fu YX, Spiotto MT, Weichselbaum RR, Lin W. Low-dose X-ray radiotherapy-radiodynamic therapy via nanoscale metal-organic frameworks enhances checkpoint blockade immunotherapy. Nature Biomedical Engineering. 2: 600-610. PMID 31015630 DOI: 10.1038/S41551-018-0203-4  0.355
2018 Huang L, David O, Cabay RJ, Valyi-Nagy K, Macias V, Zhong R, Wenig B, Feldman L, Weichselbaum RR, Spiotto MT. Molecular Classification of Lymph Node Metastases Subtypes Predict for Survival in Head and Neck Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30573692 DOI: 10.1158/1078-0432.Ccr-18-1884  0.374
2018 Foster C, Rusthoven C, Sher D, Feldman L, Pasquinelli M, Spiotto M, Koshy M. Adjuvant Chemotherapy Following Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung Cancer Is Associated with Decreased Overall Survival: A National Cancer Database Analysis International Journal of Radiation Oncology*Biology*Physics. 102: e682. DOI: 10.1016/J.Ijrobp.2018.07.1840  0.39
2018 Huang L, David O, Cabay R, Valyi-Nagy K, Macias V, Weichselbaum R, Spiotto M. Molecular Classification of Lymph Node Metastases in HPV-Negative Head and Neck Cancers Identify Distinct Phenotypes That Predict for Survival International Journal of Radiation Oncology*Biology*Physics. 102: S201-S202. DOI: 10.1016/J.Ijrobp.2018.07.102  0.353
2018 Seiwert T, Melotek J, Foster C, Blair E, Karrison T, Agrawal N, Portugal L, Gooi Z, Stenson K, Brisson R, Arshad S, Dekker A, Kochanny S, Saloura V, Spiotto M, et al. OPTIMA—A Phase 2 Trial of Induction Chemotherapy Response-Stratified Radiation Therapy Dose and Volume De-escalation for HPV+ Oropharyngeal Cancer: Efficacy, Toxicity, and HPV Subtype Analysis International Journal of Radiation Oncology*Biology*Physics. 100: 1309. DOI: 10.1016/J.Ijrobp.2017.12.025  0.334
2017 Koshy M, Malik R, Spiotto M, Mahmood U, Rusthoven CG, Sher DJ. Association between intensity modulated radiotherapy and survival in patients with stage III non-small cell lung cancer treated with chemoradiotherapy. Lung Cancer (Amsterdam, Netherlands). 108: 222-227. PMID 28625640 DOI: 10.1016/J.Lungcan.2017.04.006  0.354
2017 Spiotto MT, Koshy M. Impact of fraction size on locally advanced oropharyngeal and nasopharyngeal cancers treated with chemoradiation. Oral Oncology. 68: 27-35. PMID 28438289 DOI: 10.1016/J.Oraloncology.2017.03.002  0.308
2017 Spiotto MT, Jefferson G, Wenig B, Markiewicz M, Weichselbaum RR, Koshy M. Differences in Survival With Surgery and Postoperative Radiotherapy Compared With Definitive Chemoradiotherapy for Oral Cavity Cancer: A National Cancer Database Analysis. Jama Otolaryngology-- Head & Neck Surgery. PMID 28426848 DOI: 10.1001/Jamaoto.2017.0012  0.362
2017 Melotek J, Seiwert TY, Blair EA, Karrison TG, Agrawal N, Portugal L, Gooi Z, Stenson K, Brisson RJ, Arshad S, Dekker A, Kochanny S, Saloura V, Spiotto MT, Villaflor VM, et al. Optima: A phase II dose and volume de-escalation trial for high- and low-risk HPV+ oropharynx cancers. Journal of Clinical Oncology. 35: 6066-6066. DOI: 10.1200/Jco.2017.35.15_Suppl.6066  0.307
2017 Melotek J, Seiwert T, Blair E, Foster C, Karrison T, Agrawal N, Portugal L, Gooi Z, Stenson K, Brisson R, Arshad S, Dekker A, Spiotto M, Villaflor V, Vokes E, et al. A Phase 2 Dose and Volume De-escalation Trial for High- and Low-Risk HPV+ Oropharynx Cancer: Efficacy, Toxicity, and Dosimetric Analyses International Journal of Radiation Oncology*Biology*Physics. 99: S135. DOI: 10.1016/J.Ijrobp.2017.06.314  0.321
2016 Spiotto M, Fu YX, Weichselbaum RR. The intersection of radiotherapy and immunotherapy: mechanisms and clinical implications. Science Immunology. 1. PMID 28018989 DOI: 10.1126/Sciimmunol.Aag1266  0.425
2016 Melotek JM, Cooper BT, Koshy M, Silverman JS, Spiotto MT. Weekly versus every-three-weeks platinum-based chemoradiation regimens for head and neck cancer. Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'Oto-Rhino-Laryngologie Et De Chirurgie Cervico-Faciale. 45: 62. PMID 27881143 DOI: 10.1186/S40463-016-0175-X  0.371
2016 Spiotto MT. Return of induction chemotherapy in head and neck squamous cell cancers: is this time different? The Lancet. Oncology. PMID 27686944 DOI: 10.1016/S1470-2045(16)30444-2  0.415
2016 Zheng W, Skowron KB, Namm JP, Burnette B, Fernandez C, Arina A, Liang H, Spiotto MT, Posner MC, Fu YX, Weichselbaum RR. Combination of radiotherapy and vaccination overcome checkpoint blockade resistance. Oncotarget. PMID 27343548 DOI: 10.18632/Oncotarget.9915  0.412
2016 Villaflor VM, Melotek JM, Karrison TG, Brisson RJ, Blair EA, Portugal L, De Souza JA, Ginat DT, Stenson KM, Langerman A, Kocherginsky M, Spiotto MT, Hannigan N, Seiwert TY, Cohen EE, et al. Response-adapted volume de-escalation (RAVD) in locally advanced head and neck cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 27: 908-13. PMID 26884588 DOI: 10.1093/Annonc/Mdw051  0.376
2016 Spiotto MT, Connell PP. Strategies to Overcome Late Complications from Radiotherapy for Childhood Head and Neck Cancers. Oral and Maxillofacial Surgery Clinics of North America. 28: 115-26. PMID 26614704 DOI: 10.1016/J.Coms.2015.07.009  0.391
2016 Jefferson GD, Wenig BL, Spiotto MT. Predictors and outcomes for chronic tracheostomy after chemoradiation for advanced laryngohypopharyngeal cancer. The Laryngoscope. 126: 385-91. PMID 26344401 DOI: 10.1002/Lary.25585  0.39
2016 Zheng W, Skowron KB, Namm JP, Burnette B, Fernandez C, Arina A, Liang H, Spiotto MT, Posner MC, Fu Y, Weichselbaum RR. Abstract LB-251: Radiotherapy sensitizes pancreatic cancer to immunotherapy by promoting T cell infiltration Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-251  0.443
2016 Spiotto M, Koshy M. Impact of Fraction Size in Nasopharyngeal and Oropharyngeal Squamous Cell Cancers Treated With Chemoradiation: An Analysis of the National Cancer Data Base International Journal of Radiation Oncology*Biology*Physics. 96: E358-E359. DOI: 10.1016/J.Ijrobp.2016.06.1532  0.411
2016 Spiotto M, Koshy M. Comparison of Surgery and Postoperative Radiation to Definitive Chemoradiation for Locally Advanced Squamous Cell Carcinoma of the Oral Cavity: An Analysis of the National Cancer Data Base International Journal of Radiation Oncology*Biology*Physics. 96: E345. DOI: 10.1016/J.Ijrobp.2016.06.1493  0.361
2016 Spiotto M, Koshy M. Postoperative Chemoradiation Improves Survival for Tongue Cancers Having Multiple Metastatic Lymph Nodes or Advanced T Stage: An Analysis of the National Cancer Data Base International Journal of Radiation Oncology*Biology*Physics. 96: E326. DOI: 10.1016/J.Ijrobp.2016.06.1449  0.377
2016 Spiotto M, Bechill J, Zhong R. miR-203 Inhibits Human Papillomavirus Oral Tumor Growth by Suppressing Proliferation in Differentiated Tumor Cells International Journal of Radiation Oncology*Biology*Physics. 94: 936. DOI: 10.1016/J.Ijrobp.2015.12.257  0.313
2016 Adeniran O, Kim H, Spiotto M, Feldman L, Hu P, Chen L, Nallari A, Qu J, Haverkos B, Rastogi S, Chilkulwar A. No Difference in Outcome Comparing 5-Fluorouracil, Hydroxyurea, and Twice Daily Radiation Therapy (FHX) to High-Dose Cisplatin and Radiation Therapy (CRT) in Advanced T-Stage Head and Neck Squamous Cell Carcinoma (ATSHNSCC): A Retrospective Study International Journal of Radiation Oncology*Biology*Physics. 94: 891. DOI: 10.1016/J.Ijrobp.2015.12.086  0.336
2016 Melotek J, Villaflor V, Karrison T, Brisson R, Blair E, Portugal L, Stenson K, de Souza J, Cohen E, Langerman A, Spiotto M, Seiwert T, Vokes E, Haraf D. Response-Adapted Volume De-escalation (RAVD) in Locally Advanced Head and Neck Cancer: Toxicity and Quality of Life Analyses International Journal of Radiation Oncology*Biology*Physics. 94: 877-878. DOI: 10.1016/J.Ijrobp.2015.12.051  0.342
2016 Melotek J, Villaflor V, Karrison T, Brisson R, Blair E, Portugal L, Stenson K, De Souza J, Cohen E, Langerman A, Spiotto M, Seiwert T, Vokes E, Haraf D. Response-Adapted Volume De-escalation (RAVD) in Locally Advanced Head and Neck Cancer: Efficacy and Human Papillomavirus–Positive Subgroup Analysis International Journal of Radiation Oncology*Biology*Physics. 94: 865. DOI: 10.1016/J.Ijrobp.2015.12.024  0.308
2015 Spiotto MT, Koshy M. Hospitalizations of more than 5 days predict for worse outcomes after radiotherapy for head and neck cancer. The Journal of Community and Supportive Oncology. 13: 367-73. PMID 26862912 DOI: 10.12788/Jcso.0175  0.346
2015 Zhong R, Bechill J, Spiotto MT. Loss of E2F1 Extends Survival and Accelerates Oral Tumor Growth in HPV-Positive Mice. Cancers. 7: 2372-85. PMID 26670255 DOI: 10.3390/Cancers7040895  0.356
2015 Zhong R, Bao R, Faber PW, Bindokas VP, Bechill J, Lingen MW, Spiotto MT. Notch1 Activation or Loss Promotes HPV-Induced Oral Tumorigenesis. Cancer Research. 75: 3958-69. PMID 26294213 DOI: 10.1158/0008-5472.Can-15-0199  0.394
2015 Koshy M, Malik R, Spiotto M, Mahmood U, Weichselbaum R, Sher D. Disparities in treatment of patients with inoperable stage I non-small cell lung cancer: a population-based analysis. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 10: 264-71. PMID 25371079 DOI: 10.1097/Jto.0000000000000418  0.385
2015 Bechill J, Zhong R, Spiotto M. Compounds Containing 2-[(E)-2-Phenylvinyl]-8-Quinolinol Core Structure Activate p53 and Act as Potential Radiation Sensitizers for Cancer Cells International Journal of Radiation Oncology*Biology*Physics. 93: S183-S184. DOI: 10.1016/J.Ijrobp.2015.07.439  0.34
2015 Melotek J, Villaflor V, Brisson R, Karrison T, Blair E, Portugal L, Stenson K, De Souza J, Cohen E, Langerman A, Spiotto M, Seiwert T, Vokes E, Haraf D. Response-Adapted Volume De-escalation (RAVD) in Human Papillomavirus-Positive Oropharyngeal Squamous Cell Cancer (OPX SCC) International Journal of Radiation Oncology*Biology*Physics. 93: S130-S131. DOI: 10.1016/J.Ijrobp.2015.07.312  0.397
2015 Spiotto M, Zhong R, Bao R, Faber P, Bechill J, Lingen M. Insertional Mutagenesis in HPV Cancers Identifies That Paradoxical Notch1 Activity Promotes Tumorigenesis International Journal of Radiation Oncology*Biology*Physics. 93: S72-S73. DOI: 10.1016/J.Ijrobp.2015.07.174  0.338
2015 Melotek J, Villaflor V, Brisson R, Karrison T, Blair E, Portugal L, Stenson K, De Souza J, Cohen E, Langerman A, Spiotto M, Seiwert T, Vokes E, Haraf D. Response-Adapted Volume Deescalation (RAVD) in Locally Advanced Head and Neck Squamous Cell Cancer (LA-HNSCC): Toxicity and Quality of Life (QOL) Analyses International Journal of Radiation Oncology*Biology*Physics. 93: E335. DOI: 10.1016/J.Ijrobp.2015.07.1400  0.356
2014 Koshy M, Malik R, Sher DJ, Spiotto M, Mahmood U, Aydogan B, Weichselbaum RR. The effect of radiotherapy dose on survival in stage III non-small-cell lung cancer patients undergoing definitive chemoradiotherapy. Clinical Lung Cancer. 15: 365-71. PMID 24984565 DOI: 10.1016/J.Cllc.2014.05.004  0.348
2014 Spiotto MT, Weichselbaum RR. Comparison of 3D confromal radiotherapy and intensity modulated radiotherapy with or without simultaneous integrated boost during concurrent chemoradiation for locally advanced head and neck cancers. Plos One. 9: e94456. PMID 24714187 DOI: 10.1371/Journal.Pone.0094456  0.325
2014 Zhong R, Pytynia M, Pelizzari C, Spiotto M. Bioluminescent imaging of HPV-positive oral tumor growth and its response to image-guided radiotherapy. Cancer Research. 74: 2073-81. PMID 24525739 DOI: 10.1158/0008-5472.Can-13-2993  0.387
2014 Zakeri K, MacEwan I, Vazirnia A, Cohen EE, Spiotto MT, Haraf DJ, Vokes EE, Weichselbaum RR, Mell LK. Race and competing mortality in advanced head and neck cancer. Oral Oncology. 50: 40-4. PMID 24134948 DOI: 10.1016/J.Oraloncology.2013.09.012  0.355
2014 Liu GF, Ranck MC, Solanki AA, Cao H, Kolokythas A, Wenig BL, Chen L, Ard S, Weichselbaum RR, Halpern H, Spiotto MT. Racial parities in outcomes after radiotherapy for head and neck cancer. Cancer. 120: 244-52. PMID 24122486 DOI: 10.1002/Cncr.28417  0.327
2014 Herman LC, Chen L, Garnett A, Feldman LE, Smith B, Weichselbaum RR, Spiotto MT. Comparison of carboplatin-paclitaxel to docetaxel-cisplatin-5-flurouracil induction chemotherapy followed by concurrent chemoradiation for locally advanced head and neck cancer. Oral Oncology. 50: 52-8. PMID 24055193 DOI: 10.1016/J.Oraloncology.2013.08.007  0.303
2014 Rudra S, Spiotto MT, Witt ME, Blair EA, Stenson K, Haraf DJ. Lymph node density--prognostic value in head and neck cancer. Head & Neck. 36: 266-72. PMID 23765406 DOI: 10.1002/Hed.23299  0.304
2014 Spiotto M, Koshy M. Unplanned Hospitalizations Greater Than 5 Days Predict for Worse Outcomes After Radiation Therapy for Head and Neck Cancer International Journal of Radiation Oncology*Biology*Physics. 90: S563-S564. DOI: 10.1016/J.Ijrobp.2014.05.1703  0.34
2014 Spiotto M, Cao H, Toback F. ACE Inhibitors Predict for Acute Kidney Injury During Chemoradiation for Head and Neck Cancer International Journal of Radiation Oncology*Biology*Physics. 90: S563. DOI: 10.1016/J.Ijrobp.2014.05.1702  0.301
2014 Feldman L, Rastogi S, Hu P, Kim H, Nallari A, Chilkulwar A, Haverkos B, Qu J, Chen L, Spiotto M. A Retrospective, Single Institution Study Comparing 5-Fluorouracil, Hydroxyurea, and Twice-Daily Radiation Therapy (FHX) to High-Dose Cisplatin + Radiation Therapy (CRT) in Advanced T Stage Head-and-Neck Squamous Cell Carcinoma (ATSHNSCC) International Journal of Radiation Oncology*Biology*Physics. 88: 481. DOI: 10.1016/J.Ijrobp.2013.11.064  0.332
2013 Spiotto MT, Pytynia M, Liu GF, Ranck MC, Widau R. Animal models to study the mutational landscape for oral cavity and oropharyngeal cancers. Journal of Oral & Maxillofacial Research. 4: e1. PMID 24422024 DOI: 10.5037/Jomr.2013.4101  0.34
2013 Spiotto M, Pelizzari C. Image Guided Radiation Therapy for Mice Developing Autochthonous Human Papillomavirus Head-and-Neck Tumors International Journal of Radiation Oncology*Biology*Physics. 87: S170-S171. DOI: 10.1016/J.Ijrobp.2013.06.441  0.335
2013 Liu G, Ranck M, Solanki A, Cao H, Kolokythas A, Wenig B, Chen L, Weichselbaum R, Halpern H, Spiotto M. Racial Parities in Outcomes After Radiation Therapy for Head-and-Neck Cancer International Journal of Radiation Oncology*Biology*Physics. 87: S80-S81. DOI: 10.1016/J.Ijrobp.2013.06.209  0.36
2013 Herman L, Garnett A, Spiotto M. Improved Outcomes With Carboplatin-Paclitaxel Compared to Docetaxel-Cisplatin-5-Fluorouracil Induction Chemotherapy in Locally-Advanced Squamous Cell Cancer of the Head and Neck International Journal of Radiation Oncology*Biology*Physics. 87: S474-S475. DOI: 10.1016/J.Ijrobp.2013.06.1254  0.41
2013 Ranck M, Liu G, Solanki A, Wenig B, Kolokythas A, Spiotto M. Improved Local Control in Head-and-Neck Cancer With Post-Radiation Therapy Neck Dissection International Journal of Radiation Oncology*Biology*Physics. 87: S470. DOI: 10.1016/J.Ijrobp.2013.06.1243  0.309
2013 Solanki A, Liu G, Ranck M, Kolokythas A, Feldman L, Howard A, Spiotto M. Similar Outcomes in Hispanics and Non-Hispanics After Radiation Therapy for Head and Neck Squamous Cell Carcinoma International Journal of Radiation Oncology*Biology*Physics. 87: S464. DOI: 10.1016/J.Ijrobp.2013.06.1228  0.322
2012 Schreiber K, Arina A, Engels B, Spiotto MT, Sidney J, Sette A, Karrison TG, Weichselbaum RR, Rowley DA, Schreiber H. Spleen cells from young but not old immunized mice eradicate large established cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 2526-33. PMID 22415314 DOI: 10.1158/1078-0432.Ccr-12-0127  0.624
2012 Spiotto M, Widau R, Zhang C, Chmura S, Connell P, Weichselbaum R. A High Throughput Cell-based Screen Identifies Compounds That Inhibit the Viral Oncoprotein E6 in Human Papillomavirus-positive Cancers International Journal of Radiation Oncology*Biology*Physics. 84: S166. DOI: 10.1016/J.Ijrobp.2012.07.429  0.404
2011 Rudra S, Spiotto M, Witt M, Blair E, Stenson K, Haraf D. Percentage of Lymph Nodes Involved Rather than Absolute Number Predicts Outcomes in Head and Neck Cancer International Journal of Radiation Oncology*Biology*Physics. 81: S547-S548. DOI: 10.1016/J.Ijrobp.2011.06.859  0.331
2010 Spiotto MT, Banh A, Papandreou I, Cao H, Galvez MG, Gurtner GC, Denko NC, Le QT, Koong AC. Imaging the unfolded protein response in primary tumors reveals microenvironments with metabolic variations that predict tumor growth. Cancer Research. 70: 78-88. PMID 20028872 DOI: 10.1158/0008-5472.Can-09-2747  0.362
2009 Spiotto M, Bahn A, Cao H, Le Q, Koong A. The Unique Microenvironments of Spontaneous Tumors Differentially Sensitize Them to Radiation International Journal of Radiation Oncology*Biology*Physics. 75: S171. DOI: 10.1016/J.Ijrobp.2009.07.400  0.319
2008 Fels DR, Ye J, Segan AT, Kridel SJ, Spiotto M, Olson M, Koong AC, Koumenis C. Preferential cytotoxicity of bortezomib toward hypoxic tumor cells via overactivation of endoplasmic reticulum stress pathways. Cancer Research. 68: 9323-30. PMID 19010906 DOI: 10.1158/0008-5472.Can-08-2873  0.401
2008 King CR, Spiotto MT. Improved outcomes with higher doses for salvage radiotherapy after prostatectomy. International Journal of Radiation Oncology, Biology, Physics. 71: 23-7. PMID 18207668 DOI: 10.1016/J.Ijrobp.2007.09.047  0.301
2007 Zhang B, Bowerman NA, Salama JK, Schmidt H, Spiotto MT, Schietinger A, Yu P, Fu YX, Weichselbaum RR, Rowley DA, Kranz DM, Schreiber H. Induced sensitization of tumor stroma leads to eradication of established cancer by T cells. The Journal of Experimental Medicine. 204: 49-55. PMID 17210731 DOI: 10.1084/Jem.20062056  0.625
2006 Spiotto MT, Schreiber H. Floxed reporter genes: Flow-cytometric selection of clonable cells expressing high levels of a target gene after tamoxifen-regulated Cre-loxP recombination. Journal of Immunological Methods. 312: 201-8. PMID 16674971 DOI: 10.1016/J.Jim.2006.02.016  0.523
2005 Spiotto MT, Schreiber H. Rapid destruction of the tumor microenvironment by CTLs recognizing cancer-specific antigens cross-presented by stromal cells. Cancer Immunity. 5: 8. PMID 15934727  0.594
2004 Spiotto MT, Rowley DA, Schreiber H. Bystander elimination of antigen loss variants in established tumors. Nature Medicine. 10: 294-8. PMID 14981514 DOI: 10.1038/Nm999  0.64
2004 Blank C, Brown I, Peterson AC, Spiotto M, Iwai Y, Honjo T, Gajewski TF. PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells. Cancer Research. 64: 1140-5. PMID 14871849 DOI: 10.1158/0008-5472.Can-03-3259  0.352
2003 Spiotto MT, Fu YX, Schreiber H. Tumor immunity meets autoimmunity: antigen levels and dendritic cell maturation. Current Opinion in Immunology. 15: 725-30. PMID 14630209 DOI: 10.1016/J.Coi.2003.09.018  0.609
2003 Spiotto MT, Reth MA, Schreiber H. Genetic changes occurring in established tumors rapidly stimulate new antibody responses. Proceedings of the National Academy of Sciences of the United States of America. 100: 5425-30. PMID 12702750 DOI: 10.1073/Pnas.0930140100  0.611
2003 Yu P, Spiotto MT, Lee Y, Schreiber H, Fu YX. Complementary role of CD4+ T cells and secondary lymphoid tissues for cross-presentation of tumor antigen to CD8+ T cells. The Journal of Experimental Medicine. 197: 985-95. PMID 12695490 DOI: 10.1084/Jem.20021804  0.582
2002 Spiotto MT, Yu P, Rowley DA, Nishimura MI, Meredith SC, Gajewski TF, Fu YX, Schreiber H. Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells. Immunity. 17: 737-47. PMID 12479820 DOI: 10.1016/S1074-7613(02)00480-6  0.603
2000 Spiotto MT, Chung TD. STAT3 mediates IL-6-induced neuroendocrine differentiation in prostate cancer cells . The Prostate. 42: 186-95. PMID 10639189 DOI: 10.1002/(Sici)1097-0045(20000215)42:3<186::Aid-Pros4>3.0.Co;2-E  0.322
2000 Spiotto MT, Chung TD. STAT3 mediates IL-6-induced growth inhibition in the human prostate cancer cell line LNCaP. The Prostate. 42: 88-98. PMID 10617865 DOI: 10.1002/(Sici)1097-0045(20000201)42:2<88::Aid-Pros2>3.0.Co;2-P  0.303
2000 Chung TD, Yu JJ, Kong TA, Spiotto MT, Lin JM. Interleukin-6 activates phosphatidylinositol-3 kinase, which inhibits apoptosis in human prostate cancer cell lines. The Prostate. 42: 1-7. PMID 10579793 DOI: 10.1002/(Sici)1097-0045(20000101)42:1<1::Aid-Pros1>3.0.Co;2-Y  0.328
2000 Chung T, Yu J, Spiotto M, Kong T. Phosphatidylinositol-3 kinase is activated by interleukin-6 and inhibits apoptosis in human prostate cancer cells International Journal of Radiation Oncology*Biology*Physics. 48: 247. DOI: 10.1016/S0360-3016(00)80291-6  0.333
2000 Chung TDK, Yu JJ, Kong TA, Spiotto MT, Lin JM. Interleukin-6 activates phosphatidylinositol-3 kinase, which inhibits apoptosis in human prostate cancer cell linesPresented at the American Association for Cancer Research Special Conference “New Research Approaches in the Prevention and Cure of Prostate Cancer,” December 2–6, 1998, Indian Wells, CA. The Prostate. 42: 1. DOI: 10.1002/(Sici)1097-0045(20000101)42:1<1::Aid-Pros1>3.3.Co;2-P  0.349
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