Katherine L. Cook, Ph.D. - Publications

Affiliations: 
2010 Wake Forest University, Winston-Salem, NC, United States 
Area:
Molecular Biology

90 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Langsten KL, Shi L, Wilson AS, Lumia S, Westwood B, Skeen AM, Xie MT, Surratt VE, Turner J, Langefeld CD, Singh R, Cook KL, Kerr BA. A Novel Metastatic Estrogen Receptor-Expressing Breast Cancer Model with Antiestrogen Responsiveness. Cancers. 15. PMID 38136319 DOI: 10.3390/cancers15245773  0.311
2023 Newman TM, Wilson AS, Clear KYJ, Tallant EA, Gallagher PE, Cook KL. Probiotic and Muscadine Grape Extract Interventions Shift the Gut Microbiome and Improve Metabolic Parameters in Female C57BL/6 Mice. Cells. 12. PMID 37998334 DOI: 10.3390/cells12222599  0.547
2023 Mackert JD, Stirling ER, Wilson AS, Westwood B, Zhao D, Lo HW, Metheny-Barlow L, Cook KL, Lesser GJ, Soto-Pantoja DR. Anti-CD47 immunotherapy as a therapeutic strategy for the treatment of breast cancer brain metastasis. Biorxiv : the Preprint Server For Biology. PMID 37546807 DOI: 10.1101/2023.07.25.550566  0.68
2023 Seger ME, Cook KL, Hsu FC, Chiba A. Examining the Impact of Cholecystectomy on Tumor Recurrence in Breast Cancer Patients. The American Surgeon. 31348231173940. PMID 37246412 DOI: 10.1177/00031348231173940  0.319
2023 Klepin HD, Tooze JA, Bitting RL, Davis B, Pleasant K, Melo AC, Cook K, Soto-Pantoja DR, Tallant EA, Gallagher PE. Study design and methods for the pilot study of muscadine grape extract supplement to improve fatigue among older adult cancer survivors (FOCUS) trial. Journal of Geriatric Oncology. 101478. PMID 36990930 DOI: 10.1016/j.jgo.2023.101478  0.702
2022 Bronson SM, Westwood B, Cook KL, Emenaker NJ, Chappell MC, Roberts DD, Soto-Pantoja DR. Discrete Correlation Summation Clustering Reveals Differential Regulation of Liver Metabolism by Thrombospondin-1 in Low-Fat and High-Fat Diet-Fed Mice. Metabolites. 12. PMID 36355119 DOI: 10.3390/metabo12111036  0.598
2022 Arnone AA, Cook KL. Gut and breast microbiota as endocrine regulators of hormone receptor-positive breast cancer risk and therapy response. Endocrinology. PMID 36282876 DOI: 10.1210/endocr/bqac177  0.389
2022 Bawaneh A, Wilson AS, Levi N, Howard-McNatt MM, Chiba A, Soto-Pantoja DR, Cook KL. Intestinal Microbiota Influence Doxorubicin Responsiveness in Triple-Negative Breast Cancer. Cancers. 14. PMID 36230772 DOI: 10.3390/cancers14194849  0.68
2022 Newman TM, Clear KYJ, Wilson AS, Soto-Pantoja DR, Ochs-Balcom HM, Cook KL. Early life dietary exposures mediate persistent shifts in the gut microbiome and visceral fat metabolism. American Journal of Physiology. Cell Physiology. PMID 35848617 DOI: 10.1152/ajpcell.00380.2021  0.584
2022 Shelkey E, Oommen D, Stirling ER, Soto-Pantoja DR, Cook KL, Lu Y, Votanopoulos KI, Soker S. Immuno-reactive cancer organoid model to assess effects of the microbiome on cancer immunotherapy. Scientific Reports. 12: 9983. PMID 35705580 DOI: 10.1038/s41598-022-13930-7  0.701
2022 Ramirez MU, Clear KYJ, Cornelius Z, Bawaneh A, Feliz-Mosquea YR, Wilson AS, Ruggiero AD, Cruz-Diaz N, Shi L, Kerr BA, Soto-Pantoja DR, Cook KL. Diet impacts triple-negative breast cancer growth, metastatic potential, chemotherapy responsiveness, and doxorubicin-mediated cardiac dysfunction. Physiological Reports. 10: e15192. PMID 35439354 DOI: 10.14814/phy2.15192  0.645
2022 Triozzi PL, Stirling ER, Song Q, Westwood B, Kooshki M, Forbes ME, Holbrook BC, Cook KL, Alexander-Miller MA, Miller LD, Zhang W, Soto-Pantoja DR. Circulating Immune Bioenergetic, Metabolic, and Genetic Signatures Predict Melanoma Patients' Response to Anti-PD-1 Immune Checkpoint Blockade. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 28: 1192-1202. PMID 35284940 DOI: 10.1158/1078-0432.CCR-21-3114  0.622
2022 Stirling ER, Bronson SM, Mackert JD, Cook KL, Triozzi PL, Soto-Pantoja DR. Metabolic Implications of Immune Checkpoint Proteins in Cancer. Cells. 11. PMID 35011741 DOI: 10.3390/cells11010179  0.654
2021 Arnone AA, Cline JM, Soto-Pantoja DR, Cook KL. Investigating the role of endogenous estrogens, hormone replacement therapy, and blockade of estrogen receptor-α activity on breast metabolic signaling. Breast Cancer Research and Treatment. PMID 34448090 DOI: 10.1007/s10549-021-06354-w  0.655
2021 Soto-Pantoja DR, Gaber M, Arnone AA, Bronson SM, Cruz-Diaz N, Wilson AS, Clear KYJ, Ramirez MU, Kucera GL, Levine EA, Lelievre SA, Chaboub L, Chiba A, Yadav H, Vidi PA, ... Cook KL, et al. Diet alters entero-mammary signaling to regulate the breast microbiome and tumorigenesis. Cancer Research. PMID 34083249 DOI: 10.1158/0008-5472.CAN-20-2983  0.693
2021 Li Y, Cook KL, Yu W, Jin L, Bouker KB, Clarke R, Hilakivi-Clarke L. Inhibition of Antiestrogen-Promoted Pro-Survival Autophagy and Tamoxifen Resistance in Breast Cancer through Vitamin D Receptor. Nutrients. 13. PMID 34069442 DOI: 10.3390/nu13051715  0.396
2020 Soto-Pantoja D, Clear K, Cook KL. Abstract P5-14-19: Targeting the unfolded protein response components differentially sensitizes breast tumors to doxorubicin while modulating chemotherapy-induced cardiotoxicities Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P5-14-19  0.728
2020 Clear K, Wilson A, Chiba A, Cook KL, Bawaneh A. Abstract B15: Gut microbiome populations modulate neoadjuvant chemotherapy responsiveness in preclinical triple-negative breast cancer murine model Cancer Research. 80. DOI: 10.1158/1538-7445.Mvc2020-B15  0.482
2020 Newman T, Wilson A, Tallant E, Gallagher P, Cook K. Intervention with Probiotics and Muscadine Grape Extract Shifts Western Diet-Associated Metabolic, Microbial, and Inflammatory Parameters to Reduce Breast Tumor Growth Current Developments in Nutrition. 4: 344-344. DOI: 10.1093/cdn/nzaa044_043  0.625
2019 Swanner J, Fahrenholtz CD, Tenvooren I, Bernish BW, Sears JJ, Hooker A, Furdui CM, Alli E, Li W, Donati GL, Cook KL, Vidi PA, Singh R. Silver nanoparticles selectively treat triple-negative breast cancer cells without affecting non-malignant breast epithelial cells in vitro and in vivo. Faseb Bioadvances. 1: 639-660. PMID 32123812 DOI: 10.1096/fba.2019-00021  0.335
2019 Ramirez MU, Hernandez SR, Soto-Pantoja DR, Cook KL. Endoplasmic Reticulum Stress Pathway, the Unfolded Protein Response, Modulates Immune Function in the Tumor Microenvironment to Impact Tumor Progression and Therapeutic Response. International Journal of Molecular Sciences. 21. PMID 31881743 DOI: 10.3390/Ijms21010169  0.701
2019 Newman TM, Vitolins MZ, Cook KL. From the Table to the Tumor: The Role of Mediterranean and Western Dietary Patterns in Shifting Microbial-Mediated Signaling to Impact Breast Cancer Risk. Nutrients. 11. PMID 31652909 DOI: 10.3390/Nu11112565  0.409
2019 Chiba A, Bawaneh A, Velazquez C, Clear KY, Wilson AS, Howard-McNatt M, Levine E, Levi-Polyachenko N, Yates-Alston SA, Diggle S, Soto-Pantoja DR, Cook KL. Neoadjuvant chemotherapy shifts breast tumor microbiota populations to regulate drug responsiveness and the development of metastasis. Molecular Cancer Research : McR. PMID 31628201 DOI: 10.1158/1541-7786.Mcr-19-0451  0.716
2019 Stirling ER, Cook KL, Roberts DD, Soto-Pantoja DR. Metabolomic Analysis Reveals Unique Biochemical Signatures Associated with Protection from Radiation Induced Lung Injury by Lack of Receptor Gene Expression. Metabolites. 9. PMID 31597291 DOI: 10.3390/Metabo9100218  0.645
2019 Tenvooren I, Jenks MZ, Rashid H, Cook KL, Muhlemann JK, Sistrunk C, Holmes J, Wang K, Bonin K, Hodges K, Lo HW, Shaikh A, Camarillo IG, Lelièvre SA, Seewaldt V, et al. Elevated leptin disrupts epithelial polarity and promotes premalignant alterations in the mammary gland. Oncogene. PMID 30670780 DOI: 10.1038/S41388-019-0687-8  0.396
2019 Bawaneh A, Wilson AS, Clear KY, Chiba A, Cook KL. Abstract 650: Gut microbiota population may be used to predict chemotherapeutic responsiveness in triple negative breast cancer Cancer Research. 79: 650-650. DOI: 10.1158/1538-7445.Am2019-650  0.502
2019 Chiba A, Bawaneh A, Velazquez C, Levine E, Cook KL. Abstract 2835: Breast tumor microbiota populations are modulated by chemotherapy and may be indicative of outcome Cancer Research. 79: 2835-2835. DOI: 10.1158/1538-7445.Am2019-2835  0.444
2018 Wärri A, Cook KL, Hu R, Jin L, Zwart A, Soto-Pantoja DR, Liu J, Finkel T, Clarke R. Autophagy and unfolded protein response (UPR) regulate mammary gland involution by restraining apoptosis-driven irreversible changes. Cell Death Discovery. 5: 40. PMID 30345078 DOI: 10.1038/S41420-018-0105-Y  0.688
2018 Shively CA, Register TC, Appt SE, Clarkson TB, Uberseder B, Clear KYJ, Wilson AS, Chiba A, Tooze JA, Cook KL. Consumption of Mediterranean versus Western Diet Leads to Distinct Mammary Gland Microbiome Populations. Cell Reports. 25: 47-56.e3. PMID 30282037 DOI: 10.1016/J.Celrep.2018.08.078  0.409
2018 Feliz-Mosquea YR, Christensen AA, Wilson AS, Westwood B, Varagic J, Meléndez GC, Schwartz AL, Chen QR, Mathews Griner L, Guha R, Thomas CJ, Ferrer M, Merino MJ, Cook KL, Roberts DD, et al. Combination of anthracyclines and anti-CD47 therapy inhibit invasive breast cancer growth while preventing cardiac toxicity by regulation of autophagy. Breast Cancer Research and Treatment. PMID 30056566 DOI: 10.1007/S10549-018-4884-X  0.709
2018 Abunimer AN, Mohammed H, Cook KL, Soto-Pantoja DR, Campos MM, Abu-Asab MS. Mitochondrial autophagosomes as a mechanism of drug resistance in breast carcinoma. Ultrastructural Pathology. 1-11. PMID 29419344 DOI: 10.1080/01913123.2017.1419328  0.677
2018 Soto-Pantoja DR, Feliz-Mosquea YR, Clear KY, Wilson AS, Cook KL. Abstract 449: Targeting PKR-like endoplasmic reticulum kinase modulates metabolism to promote T-cell effector function and PD1 immunotherapy responsiveness Cancer Research. 78: 449-449. DOI: 10.1158/1538-7445.Am2018-449  0.686
2018 Feliz-Mosquea YR, Stirling E, Cook KL, Wilson A, Bharadwaj M, Molina AJ, Yamaleyeva L, Triozzi PL, Soto-Pantoja DR. Abstract 3528: Anti-CD47 immunotherapy regulates T cell metabolism and hypoxia in the tumor microenvironment Cancer Research. 78: 3528-3528. DOI: 10.1158/1538-7445.Am2018-3528  0.677
2018 Fahrenholtz CD, Swanner J, Sears J, Cook K, Vidi P, Singh R. Abstract B123: A mesenchymal subset of cancers with elevated ZEB1 expression is sensitive to low doses of silver nanoparticles Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-B123  0.469
2017 Soto-Pantoja DR, Wilson AS, Clear KY, Westwood B, Triozzi PL, Cook KL. Unfolded protein response signaling impacts macrophage polarity to modulate breast cancer cell clearance and melanoma immune checkpoint therapy responsiveness. Oncotarget. 8: 80545-80559. PMID 29113324 DOI: 10.18632/Oncotarget.19849  0.716
2017 Cook KL, Soto-Pantoja DR. "UPRegulation" of CD47 by the endoplasmic reticulum stress pathway controls anti-tumor immune responses. Biomarker Research. 5: 26. PMID 28815041 DOI: 10.1186/S40364-017-0105-8  0.72
2017 Zhang X, Cook KL, Warri A, Cruz IM, Rosim M, Riskin J, Helferich W, Doerge D, Clarke R, Hilakivi-Clarke L. Lifetime Genistein Intake Increases the Response of Mammary Tumors to Tamoxifen in Rats. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 23: 814-824. PMID 28148690 DOI: 10.1158/1078-0432.Ccr-16-1735  0.417
2017 Hilakivi-Clarke L, Wärri A, Bouker KB, Zhang X, Cook KL, Jin L, Zwart A, Nguyen N, Hu R, Cruz MI, de Assis S, Wang X, Xuan J, Wang Y, Wehrenberg B, et al. Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model. Journal of the National Cancer Institute. 109. PMID 27609189 DOI: 10.1093/Jnci/Djw188  0.427
2017 Cook K, Wilson A, Westwood B, Soto-Pantoja. Abstract P2-04-06: Targeting of the unfolded protein response signaling arms differentially regulates macrophage proliferation, plasticity, and breast cancer cell clearance Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P2-04-06  0.537
2017 Swanner JL, Tenvooren I, Bernish BW, Fahrenholtz CD, Vidi PA, Cook KL, Singh RN. Abstract B47: Silver nanoparticles exhibit subtype specific cytotoxic and therapeutic effects in claudin low breast cancer in vitro and in vivo Cancer Research. 77. DOI: 10.1158/1538-7445.Epso16-B47  0.497
2017 Mosquea YRF, Pantoja DRS, Wilson A, Triozzi PL, Cook KL. Abstract 1704: UPR signaling promotes T-cell dysfunction to prevent immune-mediated cancer cell killing and immune checkpoint therapy resistance Cancer Research. 77: 1704-1704. DOI: 10.1158/1538-7445.Am2017-1704  0.427
2016 Cook KL, Soto-Pantoja DR, Clarke PA, Cruz MI, Zwart A, Wärri A, Hilakivi-Clarke L, Roberts DD, Clarke R. Endoplasmic Reticulum Stress Protein GRP78 Modulates Lipid Metabolism to Control Drug Sensitivity and Antitumor Immunity in Breast Cancer. Cancer Research. 76: 5657-5670. PMID 27698188 DOI: 10.1158/0008-5472.Can-15-2616  0.704
2016 Sumis A, Cook K, Andrade FO, Hu R, Kidney E, Zhang X, Kim D, Carney E, Nguyen N, Yu W, Bouker KB, Cruz I, Clarke R, Hilakivi-Clarke L. Social isolation induces autophagy in the mouse mammary gland: link to increased mammary cancer risk. Endocrine-Related Cancer. PMID 27550962 DOI: 10.1530/Erc-16-0359  0.342
2016 Cook KL, Schwartz-Roberts JL, Baumann WT, Clarke R. Linking autophagy with inflammation through IRF1 signaling in ER+ breast cancer. Molecular & Cellular Oncology. 3: e1023928. PMID 27308537 DOI: 10.1080/23723556.2015.1023928  0.453
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Cook KL, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886  0.59
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Cook KL, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.632
2016 Brentville VA, Metheringham RL, Gunn B, Symonds P, Daniels I, Gijon M, Cook K, Xue W, Durrant LG. Citrullinated Vimentin Presented on MHC-II in Tumor Cells Is a Target for CD4+ T-Cell-Mediated Antitumor Immunity. Cancer Research. 76: 548-60. PMID 26719533 DOI: 10.1158/0008-5472.CAN-15-1085  0.303
2016 Clarke R, Clarke PAG, Wärri A, Cook KL. Abstract 904: Heterozygous ATG7 inhibition enhances endocrine therapy responsiveness through regulation of damage associated molecular patterns and priming the immune system in ER+ breast tumors Cancer Research. 76: 904-904. DOI: 10.1158/1538-7445.Am2016-904  0.529
2016 Hilakivi-Clarke LA, Andrade FO, Sumis A, Bouker KB, Hu R, Clarke R, Cook KL. Abstract 1027: Autophagy as a mediator of increased mammary cancer risk in socially isolated mice Cancer Research. 76: 1027-1027. DOI: 10.1158/1538-7445.Am2016-1027  0.384
2015 Cook KL, Clarke R. Overcoming cancer resistance. Future Medicinal Chemistry. 7: 1471. PMID 26334204 DOI: 10.4155/Fmc.15.113  0.358
2015 Cook KL, Clarke R. Role of GRP78 in promoting therapeutic-resistant breast cancer. Future Medicinal Chemistry. 7: 1529-34. PMID 26302335 DOI: 10.4155/Fmc.15.80  0.448
2015 Clarke R, Cook KL. Unfolding the Role of Stress Response Signaling in Endocrine Resistant Breast Cancers. Frontiers in Oncology. 5: 140. PMID 26157705 DOI: 10.3389/Fonc.2015.00140  0.461
2015 Schwartz-Roberts JL, Cook KL, Chen C, Shajahan-Haq AN, Axelrod M, Wärri A, Riggins RB, Jin L, Haddad BR, Kallakury BV, Baumann WT, Clarke R. Interferon regulatory factor-1 signaling regulates the switch between autophagy and apoptosis to determine breast cancer cell fate. Cancer Research. 75: 1046-55. PMID 25576084 DOI: 10.1158/0008-5472.Can-14-1851  0.474
2015 Zhang X, Cook K, Hilakivi-Clarke L. Abstract 904: Lifetime genistein alters mammary tumors’ response to anti-estrogen tamoxifen treatment by affecting immune function in rats Cancer Research. 75: 904-904. DOI: 10.1158/1538-7445.Am2015-904  0.411
2015 Cook KL, Clarke R. Abstract 1257: In vivo inhibition of GRP78 potentiates antiestrogen therapy effectiveness in ER+ breast tumors Cancer Research. 75: 1257-1257. DOI: 10.1158/1538-7445.Am2015-1257  0.499
2014 Cook KL, Clarke R. Estrogen receptor-α signaling and localization regulates autophagy and unfolded protein response activation in ER+ breast cancer. Receptors & Clinical Investigation. 1. PMID 26005699 DOI: 10.14800/Rci.316  0.465
2014 Cook KL, Soto-Pantoja DR, Jin L, Abu-Asab M, Clarke R. When is a vesicle not just a vesicle: mitochondrial spheroids and mitochondrial autophagosomes. Cell & Bioscience. 4: 66. PMID 25699171 DOI: 10.1186/2045-3701-4-66  0.628
2014 Figg WD, Cook K, Clarke R. Aromatase inhibitor plus ovarian suppression as adjuvant therapy in premenopausal women with breast cancer. Cancer Biology & Therapy. 15: 1586-7. PMID 25535893 DOI: 10.4161/15384047.2014.972783  0.422
2014 Shajahan-Haq AN, Cook KL, Schwartz-Roberts JL, Eltayeb AE, Demas DM, Warri AM, Facey CO, Hilakivi-Clarke LA, Clarke R. MYC regulates the unfolded protein response and glucose and glutamine uptake in endocrine resistant breast cancer. Molecular Cancer. 13: 239. PMID 25339305 DOI: 10.1186/1476-4598-13-239  0.468
2014 Cook KL, Wärri A, Soto-Pantoja DR, Clarke PA, Cruz MI, Zwart A, Clarke R. Hydroxychloroquine inhibits autophagy to potentiate antiestrogen responsiveness in ER+ breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 3222-32. PMID 24928945 DOI: 10.1158/1078-0432.Ccr-13-3227  0.724
2014 Cook KL, Clarke PA, Parmar J, Hu R, Schwartz-Roberts JL, Abu-Asab M, Wärri A, Baumann WT, Clarke R. Knockdown of estrogen receptor-α induces autophagy and inhibits antiestrogen-mediated unfolded protein response activation, promoting ROS-induced breast cancer cell death. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 3891-905. PMID 24858277 DOI: 10.1096/Fj.13-247353  0.488
2014 Soto-Pantoja DR, Shih HB, Maxhimer JB, Cook KL, Ghosh A, Isenberg JS, Roberts DD. Thrombospondin-1 and CD47 signaling regulate healing of thermal injury in mice. Matrix Biology : Journal of the International Society For Matrix Biology. 37: 25-34. PMID 24840925 DOI: 10.1016/J.Matbio.2014.05.003  0.628
2014 Cook KL, Soto-Pantoja DR, Abu-Asab M, Clarke PA, Roberts DD, Clarke R. Mitochondria directly donate their membrane to form autophagosomes during a novel mechanism of parkin-associated mitophagy. Cell & Bioscience. 4: 16. PMID 24669863 DOI: 10.1186/2045-3701-4-16  0.596
2014 Shajahan-Haq A, Cook K, Schwartz-Roberts J, Eltayeb A, Demas D, Warri A, Hilakivi-Clarke L, Clarke R. Glutamine metabolism and the unfolded protein response in MYC-driven breast cancer Cancer & Metabolism. 2. DOI: 10.1186/2049-3002-2-S1-P66  0.453
2014 Cook K, Clarke P, Warri A, Clarke R. Inhibiting glucose-regulated protein 78 modulates lipid metabolism through controlling stearoyl-CoA desaturase 1 Cancer & Metabolism. 2. DOI: 10.1186/2049-3002-2-S1-P16  0.415
2014 Shajahan-Haq AN, Cook KL, Schwartz-Roberts JL, Eltayeb AE, Demas DM, Warri AM, Hilakivi-Clarke LA, Clarke R. Abstract 679: Glutamine metabolism in MYC-driven antiestrogen resistant breast cancer cells confers metabolic flexibility through the unfolded protein response Cancer Research. 74: 679-679. DOI: 10.1158/1538-7445.Am2014-679  0.464
2014 Cook KL, Clarke PAG, Axelrod M, Wärri A, Clarke R. Abstract 2443: Novel role of glucose-regulated protein 78 mediating lipid metabolism through controlling stearoyl-CoA desaturase 1 Cancer Research. 74: 2443-2443. DOI: 10.1158/1538-7445.Am2014-2443  0.484
2013 Parmar JH, Cook KL, Shajahan-Haq AN, Clarke PA, Tavassoly I, Clarke R, Tyson JJ, Baumann WT. Modelling the effect of GRP78 on anti-oestrogen sensitivity and resistance in breast cancer. Interface Focus. 3: 20130012. PMID 24511377 DOI: 10.1098/Rsfs.2013.0012  0.414
2013 Cook KL, Clarke PA, Clarke R. Targeting GRP78 and antiestrogen resistance in breast cancer. Future Medicinal Chemistry. 5: 1047-57. PMID 23734687 DOI: 10.4155/Fmc.13.77  0.456
2013 Schwartz-Roberts JL, Shajahan AN, Cook KL, Wärri A, Abu-Asab M, Clarke R. GX15-070 (obatoclax) induces apoptosis and inhibits cathepsin D- and L-mediated autophagosomal lysis in antiestrogen-resistant breast cancer cells Molecular Cancer Therapeutics. 12: 448-459. PMID 23395885 DOI: 10.1158/1535-7163.Mct-12-0617  0.474
2013 Shajahan AN, Cook KL, Schwartz-Roberts JL, Eltayeb AE, Demas DM, Warri A, Hilakivi-Clarke L, Metallo S, Clarke R. Abstract 5397: MYC-driven glutamine metabolism promotes antiestrogen resistance in breast cancer. Cancer Research. 73: 5397-5397. DOI: 10.1158/1538-7445.Am2013-5397  0.476
2013 Clarke PA, Cook K, Hu R, Schwartz JL, Abu-Asab M, Warri A, Clarke R. Abstract 4046: Estrogen receptor-α coordinates the unfolded protein response,autophagy, and reactive oxygen species generation to regulate breast cancer survival. Cancer Research. 73: 4046-4046. DOI: 10.1158/1538-7445.Am2013-4046  0.499
2013 Schwartz-Roberts JL, Cook KL, Shajahan AN, Axelrod M, Warri A, Clarke R. Abstract 1677: Inhibition of autophagy proteins ATG7 and BECN1 correlates with increased interferon regulatory factor-1 (IRF1) protein expression through STAT1 phosphorylation. Cancer Research. 73: 1677-1677. DOI: 10.1158/1538-7445.Am2013-1677  0.524
2013 Cook KL, Warri A, Hu R, Jin L, Zwart A, Pantoja DRS, Liu J, Finkel T, Clarke R. Abstract 1667: Autophagy and unfolded protein response (UPR) signaling regulates progression of apoptosis in mammary gland involution. Cancer Research. 73: 1667-1667. DOI: 10.1158/1538-7445.Am2013-1667  0.427
2013 Nguyen N, Warri A, Clarke R, Cook K, Cruz I, Assis Sd, Kim D, Lu J, Zwart A, Xuan J, Hilakivi-Clarke L. Abstract 1390: In utero estrogenic exposures increase tamoxifen resistance in a new pre-clinical model of estrogen receptor positive breast cancer. Cancer Research. 73: 1390-1390. DOI: 10.1158/1538-7445.Am2013-1390  0.481
2012 Aiyer HS, Bouker KB, Cook KL, Facey CO, Hu R, Schwartz JL, Shajahan AN, Hilakivi-Clarke L, Clarke R. Interaction of dietary polyphenols with molecular signaling pathways of antiestrogen resistance: possible role in breast cancer recurrence. Hormone Molecular Biology and Clinical Investigation. 9: 127-41. PMID 25436704 DOI: 10.1515/Hmbci-2012-0022  0.475
2012 Cook KL, Clarke R. Heat shock 70 kDa protein 5/glucose-regulated protein 78 "AMP"ing up autophagy Autophagy. 8: 1827-1829. PMID 22931685 DOI: 10.4161/Auto.21765  0.452
2012 Cook KL, Shajahan AN, Wärri A, Jin L, Hilakivi-Clarke LA, Clarke R. Glucose-regulated protein 78 controls cross-talk between apoptosis and autophagy to determine antiestrogen responsiveness. Cancer Research. 72: 3337-49. PMID 22752300 DOI: 10.1158/0008-5472.Can-12-0269  0.467
2012 Clarke R, Cook KL, Hu R, Facey CO, Tavassoly I, Schwartz JL, Baumann WT, Tyson JJ, Xuan J, Wang Y, Wärri A, Shajahan AN. Endoplasmic reticulum stress, the unfolded protein response, autophagy, and the integrated regulation of breast cancer cell fate. Cancer Research. 72: 1321-31. PMID 22422988 DOI: 10.1158/0008-5472.Can-11-3213  0.396
2012 Zhang X, Warri A, Cruz IM, Cook K, Clarke R, Hilakivi-Clarke L. Abstract LB-167: Prepubertal or lifetime genistein intake reduces risk of tamoxifen resistance in rats Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-167  0.358
2012 Cook KL, Shajahan AN, Jin L, Warri A, Hilakivi-Clarke LA, Clarke R. Abstract 4995: Glucose-regulated protein 78 regulates crosstalk between apoptosis and autophagy to determine antiestrogen responsiveness Cancer Research. 72: 4995-4995. DOI: 10.1158/1538-7445.Am2012-4995  0.451
2011 Clarke R, Shajahan AN, Wang Y, Tyson JJ, Riggins RB, Weiner LM, Bauman WT, Xuan J, Zhang B, Facey C, Aiyer H, Cook K, Hickman FE, Tavassoly I, Verdugo A, et al. Endoplasmic reticulum stress, the unfolded protein response, and gene network modeling in antiestrogen resistant breast cancer. Hormone Molecular Biology and Clinical Investigation. 5: 35-44. PMID 23930139 DOI: 10.1515/Hmbci.2010.073  0.39
2011 Cook KL, Shajahan AN, Clarke R. Autophagy and endocrine resistance in breast cancer Expert Review of Anticancer Therapy. 11: 1283-1294. PMID 21916582 DOI: 10.1586/Era.11.111  0.487
2011 Gallagher PE, Cook K, Soto-Pantoja D, Menon J, Tallant EA. Angiotensin peptides and lung cancer. Current Cancer Drug Targets. 11: 394-404. PMID 21395552 DOI: 10.2174/156800911795538048  0.731
2011 Arter AL, Cook KL, Soto-Pantoja DL, Gallagher PE, Tallant EA. Abstract 3274: Molecular mechanisms for the angiotensin-(1-7)-mediated reduction in triple negative breast cancer Cancer Research. 71: 3274-3274. DOI: 10.1158/1538-7445.Am2011-3274  0.686
2011 Shajahan AN, Hickman FE, Cook K, Clarke R. Abstract 2070: XBP-1 promotes cell survival by activating the unfolded protein response (UPR) in antiestrogen resistance in breast cancer Cancer Research. 71: 2070-2070. DOI: 10.1158/1538-7445.Am2011-2070  0.489
2011 Clarke R, Shajahan A, Cook K, Hickman F, Facey C. P4-01-12: The Unfolded Protein Response (UPR) and Pro-Survival Autophagy Contributes to Antiestrogen Resistance in Breast Cancer. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P4-01-12  0.48
2010 Cook KL, Metheny-Barlow LJ, Tallant EA, Gallagher PE. Angiotensin-(1-7) reduces fibrosis in orthotopic breast tumors Cancer Research. 70: 8319-8328. PMID 20837666 DOI: 10.1158/0008-5472.Can-10-1136  0.656
2010 Cook KL, Tallant EA, Gallagher PE. Abstract 2273: Angiotensin-(1-7) reduces angiogenesis and fibrosis in orthotopic breast cancer Cancer Research. 70: 2273-2273. DOI: 10.1158/1538-7445.Am10-2273  0.679
2009 Cook K, Pantoja DS, Gallagher P, Tallant E. Angiotensin-(1-7) inhibition of human breast tumors with distinct hormone receptor expression results in a differential regulation of Akt. Cancer Research. 69: 3127. DOI: 10.1158/0008-5472.Sabcs-3127  0.429
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