| Year |
Citation |
Score |
| 2023 |
Portillo AL, Monteiro JK, Rojas EA, Ritchie TM, Gillgrass A, Ashkar AA. Charting a killer course to the solid tumor: strategies to recruit and activate NK cells in the tumor microenvironment. Frontiers in Immunology. 14: 1286750. PMID 38022679 DOI: 10.3389/fimmu.2023.1286750 |
0.321 |
|
| 2023 |
Feng E, Monteiro JK, Portillo AL, Balint E, Ashkar AA. NK cell-derived IFN-γ regulates macrophage-mediated immunopathology during viral infection. The Journal of Infectious Diseases. PMID 36994782 DOI: 10.1093/infdis/jiad084 |
0.382 |
|
| 2022 |
MacDonald K, Botelho F, Ashkar AA, Richards CD. Type I Interferon Signaling is Required for Oncostatin-M Driven Inflammatory Responses in Mouse Lung. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. PMID 36346324 DOI: 10.1089/jir.2022.0136 |
0.368 |
|
| 2021 |
Portillo AL, Hogg R, Ashkar AA. Production of human CAR-NK cells with lentiviral vectors and functional assessment . Star Protocols. 2: 100956. PMID 34825217 DOI: 10.1016/j.xpro.2021.100956 |
0.318 |
|
| 2021 |
Vito A, Salem O, El-Sayes N, MacFawn IP, Portillo AL, Milne K, Harrington D, Ashkar AA, Wan Y, Workenhe ST, Nelson BH, Bruno TC, Mossman KL. Immune checkpoint blockade in triple negative breast cancer influenced by B cells through myeloid-derived suppressor cells. Communications Biology. 4: 859. PMID 34253827 DOI: 10.1038/s42003-021-02375-9 |
0.302 |
|
| 2020 |
Cavallari JF, Barra NG, Foley KP, Lee A, Duggan BM, Henriksbo BD, Anhê FF, Ashkar AA, Schertzer JD. Postbiotics for NOD2 require non-hematopoietic RIPK2 to improve blood glucose and metabolic inflammation in mice. American Journal of Physiology. Endocrinology and Metabolism. PMID 32101030 DOI: 10.1152/Ajpendo.00033.2020 |
0.366 |
|
| 2019 |
Karimi Y, Giles EC, Vahedi F, Chew MV, Nham T, Loukov D, Lee AJ, Bowdish DM, Ashkar AA. IFN- signalling regulates RAW 264.7 macrophage activation, cytokine production, and killing activity. Innate Immunity. 1753425919878839. PMID 31615311 DOI: 10.1177/1753425919878839 |
0.389 |
|
| 2019 |
Poznanski SM, Ashkar AA. What Defines NK Cell Functional Fate: Phenotype or Metabolism? Frontiers in Immunology. 10: 1414. PMID 31275330 DOI: 10.3389/Fimmu.2019.01414 |
0.431 |
|
| 2019 |
Lee AJ, Mian F, Poznanski SM, Stackaruk M, Chan T, Chew MV, Ashkar AA. Type I Interferon Receptor on NK Cells Negatively Regulates Interferon-γ Production. Frontiers in Immunology. 10: 1261. PMID 31214198 DOI: 10.3389/Fimmu.2019.01261 |
0.511 |
|
| 2019 |
Henriksbo BD, Tamrakar AK, Xu J, Duggan BM, Cavallari JF, Phulka J, Stampfli MR, Ashkar AA, Schertzer JD. Statins Promote IL-1β-Dependent Adipocyte Insulin Resistance via Lower Prenylation not Cholesterol. Diabetes. PMID 31010959 DOI: 10.2337/Db18-0999 |
0.306 |
|
| 2019 |
Wang H, Kwon YH, Dewan V, Vahedi F, Syed S, Fontes ME, Ashkar AA, Surette MG, Khan WI. TLR2 Plays a Pivotal Role in Mediating Mucosal Serotonin Production in the Gut. Journal of Immunology (Baltimore, Md. : 1950). PMID 30952815 DOI: 10.4049/Jimmunol.1801034 |
0.334 |
|
| 2018 |
Poznanski SM, Ashkar AA. Shining light on the significance of NK cell CD56 brightness. Cellular & Molecular Immunology. PMID 30275534 DOI: 10.1038/S41423-018-0163-3 |
0.317 |
|
| 2018 |
Lee AJ, Ashkar AA. The Dual Nature of Type I and Type II Interferons. Frontiers in Immunology. 9: 2061. PMID 30254639 DOI: 10.3389/Fimmu.2018.02061 |
0.365 |
|
| 2018 |
Poznanski SM, Barra NG, Ashkar AA, Schertzer JD. Immunometabolism of T cells and NK cells: metabolic control of effector and regulatory function. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. PMID 30066126 DOI: 10.1007/S00011-018-1174-3 |
0.405 |
|
| 2018 |
Poznanski SM, Nham T, Chew MV, Lee AJ, Hammill JA, Fan IY, Butcher M, Bramson JL, Lee DA, Hirte HW, Ashkar AA. Expanded CD56superbrightCD16+ NK cells from ovarian cancer patients are cytotoxic against autologous tumor in a patient-derived xenograft murine model. Cancer Immunology Research. PMID 30018043 DOI: 10.1158/2326-6066.Cir-18-0144 |
0.398 |
|
| 2018 |
Vahedi F, Lee AJ, Collins SE, Chew MV, Lusty E, Chen B, Dubey A, Richards CD, Feld JJ, Russell RS, Mossman KL, Ashkar AA. IL-15 and IFN-γ signal through the ERK pathway to inhibit HCV replication, independent of type I IFN signaling. Cytokine. PMID 29908921 DOI: 10.1016/J.Cyto.2018.06.006 |
0.381 |
|
| 2018 |
Nazli A, Dizzell S, Zahoor MA, Ferreira VH, Kafka J, Woods MW, Ouellet M, Ashkar AA, Tremblay MJ, Bowdish DM, Kaushic C. Interferon-β induced in female genital epithelium by HIV-1 glycoprotein 120 via Toll-like-receptor 2 pathway acts to protect the mucosal barrier. Cellular & Molecular Immunology. PMID 29553138 DOI: 10.1038/Cmi.2017.168 |
0.311 |
|
| 2018 |
Nham T, Poznanski SM, Fan IY, Shenouda MM, Chew MV, Lee AJ, Vahedi F, Karimi Y, Butcher M, Lee DA, Hirte H, Ashkar AA. Ex vivo-expanded NK cells from blood and ascites of ovarian cancer patients are cytotoxic against autologous primary ovarian cancer cells. Cancer Immunology, Immunotherapy : Cii. PMID 29299659 DOI: 10.1007/S00262-017-2112-X |
0.445 |
|
| 2018 |
Poznanski SM, Nham T, Chew MV, Lee AJ, Fan IY, Lee DA, Hirte H, Ashkar AA. Abstract 2556: Expanded ovarian cancer patient NK cells represent a novel, cytotoxic phenotype and reduce autologous tumor in a patient-derived xenograft ovarian cancer model Immunology. DOI: 10.1158/1538-7445.Am2018-2556 |
0.304 |
|
| 2017 |
Barra NG, Fan IY, Gillen JB, Chew M, Marcinko K, Steinberg GR, Gibala MJ, Ashkar AA. High Intensity Interval Training Increases Natural Killer Cell Number and Function in Obese Breast Cancer-challenged Mice and Obese Women. Journal of Cancer Prevention. 22: 260-266. PMID 29302585 DOI: 10.15430/Jcp.2017.22.4.260 |
0.362 |
|
| 2017 |
Nham T, Poznanski SM, Fan IY, Vahedi F, Shenouda MM, Lee AJ, Chew MV, Hogg RT, Lee DA, Ashkar AA. Ex Vivo-expanded Natural Killer Cells Derived From Long-term Cryopreserved Cord Blood are Cytotoxic Against Primary Breast Cancer Cells. Journal of Immunotherapy (Hagerstown, Md. : 1997). PMID 29189387 DOI: 10.1097/Cji.0000000000000192 |
0.406 |
|
| 2017 |
Nguyen PV, Wessels JM, Mueller K, Vahedi F, Anipindi V, Verschoor CP, Chew M, Deshiere A, Karniychuk U, Mazzulli T, Tremblay MJ, Ashkar AA, Kaushic C. Frequency of Human CD45+ Target Cells is a Key Determinant of Intravaginal HIV-1 Infection in Humanized Mice. Scientific Reports. 7: 15263. PMID 29127409 DOI: 10.1038/S41598-017-15630-Z |
0.335 |
|
| 2017 |
Vahedi F, Nham T, Poznanski SM, Chew MV, Shenouda MM, Lee D, Ashkar AA. Ex Vivo Expanded Human NK Cells Survive and Proliferate in Humanized Mice with Autologous Human Immune Cells. Scientific Reports. 7: 12083. PMID 28935883 DOI: 10.1038/S41598-017-12223-8 |
0.498 |
|
| 2017 |
Vahedi F, Giles EC, Ashkar AA. The Application of Humanized Mouse Models for the Study of Human Exclusive Viruses. Methods in Molecular Biology (Clifton, N.J.). 1656: 1-56. PMID 28808960 DOI: 10.1007/978-1-4939-7237-1_1 |
0.314 |
|
| 2017 |
Shenouda MM, Gillgrass A, Nham T, Hogg R, Lee AJ, Chew MV, Shafaei M, Aarts C, Lee DA, Hassell J, Bane A, Dhesy-Thind S, Ashkar AA. Ex vivo expanded natural killer cells from breast cancer patients and healthy donors are highly cytotoxic against breast cancer cell lines and patient-derived tumours. Breast Cancer Research : Bcr. 19: 76. PMID 28668076 DOI: 10.1186/S13058-017-0867-9 |
0.366 |
|
| 2017 |
Lusty E, Poznanski SM, Kwofie K, Mandur TS, Lee DA, Richards CD, Ashkar AA. IL-18/IL-15/IL-12 synergy induces elevated and prolonged IFN-γ production by ex vivo expanded NK cells which is not due to enhanced STAT4 activation. Molecular Immunology. 88: 138-147. PMID 28644973 DOI: 10.1016/J.Molimm.2017.06.025 |
0.443 |
|
| 2017 |
Poznanski SM, Lee AJ, Nham T, Lusty E, Larché MJ, Lee DA, Ashkar AA. Combined Stimulation with Interleukin-18 and Interleukin-12 Potently Induces Interleukin-8 Production by Natural Killer Cells. Journal of Innate Immunity. PMID 28633138 DOI: 10.1159/000477172 |
0.435 |
|
| 2017 |
Lee AJ, Chen B, Chew MV, Barra NG, Shenouda MM, Nham T, van Rooijen N, Jordana M, Mossman KL, Schreiber RD, Mack M, Ashkar AA. Inflammatory monocytes require type I interferon receptor signaling to activate NK cells via IL-18 during a mucosal viral infection. The Journal of Experimental Medicine. PMID 28264883 DOI: 10.1084/Jem.20160880 |
0.531 |
|
| 2017 |
Karimi Y, Poznanski SM, Vahedi F, Chen B, Chew MV, Lee AJ, Ashkar AA. Type I interferon signalling is not required for the induction of endotoxin tolerance. Cytokine. 95: 7-11. PMID 28189043 DOI: 10.1016/J.Cyto.2017.01.017 |
0.363 |
|
| 2016 |
Chen B, Lee AJ, Chew MV, Ashkar AA. NK cells require antigen-specific memory CD4+ T cells to mediate superior effector functions during HSV-2 recall responses in vitro. Journal of Leukocyte Biology. PMID 27974365 DOI: 10.1189/Jlb.4A0416-192R |
0.495 |
|
| 2016 |
Krneta T, Gillgrass A, Poznanski S, Chew M, Lee AJ, Kolb M, Ashkar AA. M2-polarized and tumor-associated macrophages alter NK cell phenotype and function in a contact-dependent manner. Journal of Leukocyte Biology. PMID 27493241 DOI: 10.1189/Jlb.3A1215-552R |
0.422 |
|
| 2016 |
Bulir DC, Liang S, Lee A, Chong S, Simms E, Stone C, Kaushic C, Ashkar A, Mahony JB. Immunization with chlamydial type III secretion antigens reduces vaginal shedding and prevents fallopian tube pathology following live C. muridarum challenge. Vaccine. PMID 27325352 DOI: 10.1016/J.Vaccine.2016.06.046 |
0.343 |
|
| 2016 |
Dykstra C, Lee AJ, Lusty EJ, Shenouda MM, Shafai M, Vahedi F, Chew MV, Collins S, Ashkar AA. Reconstitution of immune cell in liver and lymph node of adult- and newborn-engrafted humanized mice. Bmc Immunology. 17: 18. PMID 27307066 DOI: 10.1186/S12865-016-0157-9 |
0.367 |
|
| 2016 |
Mian F, Kandiah N, Chew M, Ashkar A, Bienenstock J, Forsythe P, Karimi K. A probiotic provides protection against acute salmonellosis in mice: Possible role of innate lymphid NKP46+ cells Journal of Functional Foods. 23: 329-338. DOI: 10.1016/J.Jff.2016.02.020 |
0.45 |
|
| 2015 |
Cuddington BP, Verschoor M, Ashkar A, Mossman KL. Enhanced efficacy with azacytidine and oncolytic BHV-1 in a tolerized cotton rat model of breast adenocarcinoma. Molecular Therapy Oncolytics. 2: 15004. PMID 27119103 DOI: 10.1038/Mto.2015.4 |
0.306 |
|
| 2015 |
Krneta T, Gillgrass A, Chew M, Ashkar AA. The breast tumor microenvironment alters the phenotype and function of natural killer cells. Cellular & Molecular Immunology. PMID 26277898 DOI: 10.1038/Cmi.2015.42 |
0.428 |
|
| 2015 |
Gillgrass AE, Chew MV, Krneta T, Ashkar AA. Overexpression of IL-15 promotes tumor destruction via NK1.1+ cells in a spontaneous breast cancer model. Bmc Cancer. 15: 293. PMID 25879689 DOI: 10.1186/S12885-015-1264-3 |
0.416 |
|
| 2015 |
Shojadoost B, Behboudi S, Villanueva AI, Brisbin JT, Ashkar AA, Sharif S. Vitamin D3 modulates the function of chicken macrophages. Research in Veterinary Science. 100: 45-51. PMID 25814176 DOI: 10.1016/J.Rvsc.2015.03.009 |
0.324 |
|
| 2015 |
Karimi K, Karimi Y, Chan J, Boudreau JE, Basset J, Chew MV, Reid S, Bramson JL, Wan Y, Ashkar AA. Type I IFN signaling on dendritic cells is required for NK cell-mediated anti-tumor immunity. Innate Immunity. 21: 626-34. PMID 25749844 DOI: 10.1177/1753425915575078 |
0.416 |
|
| 2015 |
Denou E, Lolmède K, Garidou L, Pomie C, Chabo C, Lau TC, Fullerton MD, Nigro G, Zakaroff-Girard A, Luche E, Garret C, Serino M, Amar J, Courtney M, Cavallari JF, ... ... Ashkar AA, et al. Defective NOD2 peptidoglycan sensing promotes diet-induced inflammation, dysbiosis, and insulin resistance. Embo Molecular Medicine. 7: 259-74. PMID 25666722 DOI: 10.15252/Emmm.201404169 |
0.309 |
|
| 2015 |
Lauber S, Wong S, Cutz JC, Tanaka M, Barra N, Lhoták S, Ashkar A, Richards CD. Novel function of Oncostatin M as a potent tumour-promoting agent in lung. International Journal of Cancer. Journal International Du Cancer. 136: 831-43. PMID 24976180 DOI: 10.1002/Ijc.29055 |
0.39 |
|
| 2014 |
Barra NG, Palanivel R, Denou E, Chew MV, Gillgrass A, Walker TD, Kong J, Richards CD, Jordana M, Collins SM, Trigatti BL, Holloway AC, Raha S, Steinberg GR, Ashkar AA. Interleukin-15 modulates adipose tissue by altering mitochondrial mass and activity. Plos One. 9: e114799. PMID 25517731 DOI: 10.1371/Journal.Pone.0114799 |
0.363 |
|
| 2014 |
Gillgrass A, Gill N, Babian A, Ashkar AA. The absence or overexpression of IL-15 drastically alters breast cancer metastasis via effects on NK cells, CD4 T cells, and macrophages. Journal of Immunology (Baltimore, Md. : 1950). 193: 6184-91. PMID 25355926 DOI: 10.4049/Jimmunol.1303175 |
0.474 |
|
| 2014 |
Taylor KE, Chew MV, Ashkar AA, Mossman KL. Novel roles of cytoplasmic ICP0: proteasome-independent functions of the RING finger are required to block interferon-stimulated gene production but not to promote viral replication. Journal of Virology. 88: 8091-101. PMID 24807717 DOI: 10.1128/Jvi.00944-14 |
0.304 |
|
| 2014 |
Chu DK, Mohammed-Ali Z, Jiménez-Saiz R, Walker TD, Goncharova S, Llop-Guevara A, Kong J, Gordon ME, Barra NG, Gillgrass AE, Van Seggelen H, Khan WI, Ashkar AA, Bramson JL, Humbles AA, et al. T helper cell IL-4 drives intestinal Th2 priming to oral peanut antigen, under the control of OX40L and independent of innate-like lymphocytes. Mucosal Immunology. 7: 1395-404. PMID 24781052 DOI: 10.1038/Mi.2014.29 |
0.444 |
|
| 2014 |
Lai R, Jeyanathan M, Shaler CR, Damjanovic D, Khera A, Horvath C, Ashkar AA, Xing Z. Restoration of innate immune activation accelerates Th1-cell priming and protection following pulmonary mycobacterial infection. European Journal of Immunology. 44: 1375-86. PMID 24519467 DOI: 10.1002/Eji.201344300 |
0.379 |
|
| 2014 |
Jeyanathan M, McCormick S, Lai R, Afkhami S, Shaler CR, Horvath CN, Damjanovic D, Zganiacz A, Barra N, Ashkar A, Jordana M, Aoki N, Xing Z. Pulmonary M. tuberculosis infection delays Th1 immunity via immunoadaptor DAP12-regulated IRAK-M and IL-10 expression in antigen-presenting cells. Mucosal Immunology. 7: 670-83. PMID 24172845 DOI: 10.1038/Mi.2013.86 |
0.458 |
|
| 2013 |
Schnittker D, Kwofie K, Ashkar A, Trigatti B, Richards CD. Oncostatin M and TLR-4 ligand synergize to induce MCP-1, IL-6, and VEGF in human aortic adventitial fibroblasts and smooth muscle cells. Mediators of Inflammation. 2013: 317503. PMID 24307759 DOI: 10.1155/2013/317503 |
0.392 |
|
| 2013 |
Nazli A, Kafka JK, Ferreira VH, Anipindi V, Mueller K, Osborne BJ, Dizzell S, Chauvin S, Mian MF, Ouellet M, Tremblay MJ, Mossman KL, Ashkar AA, Kovacs C, Bowdish DM, et al. HIV-1 gp120 induces TLR2- and TLR4-mediated innate immune activation in human female genital epithelium. Journal of Immunology (Baltimore, Md. : 1950). 191: 4246-58. PMID 24043886 DOI: 10.4049/Jimmunol.1301482 |
0.303 |
|
| 2013 |
Stackaruk ML, Lee AJ, Ashkar AA. Type I interferon regulation of natural killer cell function in primary and secondary infections. Expert Review of Vaccines. 12: 875-84. PMID 23984959 DOI: 10.1586/14760584.2013.814871 |
0.484 |
|
| 2013 |
Mian MF, Ahmed AN, Rad M, Babaian A, Bowdish D, Ashkar AA. Length of dsRNA (poly I:C) drives distinct innate immune responses, depending on the cell type. Journal of Leukocyte Biology. 94: 1025-36. PMID 23911868 DOI: 10.1189/Jlb.0312125 |
0.369 |
|
| 2013 |
Lee AJ, Kandiah N, Karimi K, Clark DA, Ashkar AA. Interleukin-15 is required for maximal lipopolysaccharide-induced abortion. Journal of Leukocyte Biology. 93: 905-12. PMID 23505315 DOI: 10.1189/Jlb.0912442 |
0.466 |
|
| 2013 |
Guerrette J, Nair P, Mian MF, Ashkar AA, Richards CD. 106 Cytokine. 63: 268. DOI: 10.1016/J.Cyto.2013.06.109 |
0.335 |
|
| 2013 |
Karimi K, Solano ME, Ashkar AA, Ho H, Steidle E, Neufeld KM, Hecher K, Bienenstock J, Arck PC. Erratum to: Regulation of pregnancy maintenance and fetal survival in mice by CD27low mature NK cells Journal of Molecular Medicine. 91: 903-904. DOI: 10.1007/S00109-013-1031-3 |
0.455 |
|
| 2012 |
Chentoufi AA, BenMohamed L, Van De Perre P, Ashkar AA. Immunity to ocular and genital herpes simplex viruses infections. Clinical & Developmental Immunology. 2012: 732546. PMID 23326289 DOI: 10.1155/2012/732546 |
0.376 |
|
| 2012 |
Barra NG, Chew MV, Reid S, Ashkar AA. Interleukin-15 treatment induces weight loss independent of lymphocytes. Plos One. 7: e39553. PMID 22768089 DOI: 10.1371/Journal.Pone.0039553 |
0.469 |
|
| 2012 |
Abdul-Careem MF, Mian MF, Yue G, Gillgrass A, Chenoweth MJ, Barra NG, Chew MV, Chan T, Al-Garawi AA, Jordana M, Ashkar AA. Critical role of natural killer cells in lung immunopathology during influenza infection in mice. The Journal of Infectious Diseases. 206: 167-77. PMID 22561366 DOI: 10.1093/Infdis/Jis340 |
0.535 |
|
| 2012 |
Abdul-Careem MF, Lee AJ, Pek EA, Gill N, Gillgrass AE, Chew MV, Reid S, Ashkar AA. Genital HSV-2 infection induces short-term NK cell memory. Plos One. 7: e32821. PMID 22457721 DOI: 10.1371/Journal.Pone.0032821 |
0.454 |
|
| 2012 |
Chenoweth MJ, Mian MF, Barra NG, Alain T, Sonenberg N, Bramson J, Lichty BD, Richards CD, Ma A, Ashkar AA. IL-15 can signal via IL-15Rα, JNK, and NF-κB to drive RANTES production by myeloid cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 4149-57. PMID 22447977 DOI: 10.4049/Jimmunol.1101883 |
0.44 |
|
| 2012 |
Mehta DR, Ashkar AA, Mossman KL. The nitric oxide pathway provides innate antiviral protection in conjunction with the type I interferon pathway in fibroblasts. Plos One. 7: e31688. PMID 22363706 DOI: 10.1371/Journal.Pone.0031688 |
0.352 |
|
| 2012 |
Karimi K, Solano ME, Ashkar AA, Ho H, Steidle EM, McVey Neufeld KA, Hecher K, Bienenstock J, Arck PC. Regulation of pregnancy maintenance and fetal survival in mice by CD27(low) mature NK cells. Journal of Molecular Medicine (Berlin, Germany). 90: 1047-57. PMID 22358070 DOI: 10.1007/S00109-012-0872-5 |
0.463 |
|
| 2012 |
Stephenson KB, Barra NG, Davies E, Ashkar AA, Lichty BD. Expressing human interleukin-15 from oncolytic vesicular stomatitis virus improves survival in a murine metastatic colon adenocarcinoma model through the enhancement of anti-tumor immunity. Cancer Gene Therapy. 19: 238-46. PMID 22158521 DOI: 10.1038/Cgt.2011.81 |
0.428 |
|
| 2011 |
Abdul-Careem MF, Firoz Mian M, Gillgrass AE, Chenoweth MJ, Barra NG, Chan T, Al-Garawi AA, Chew MV, Yue G, van Roojen N, Xing Z, Ashkar AA. FimH, a TLR4 ligand, induces innate antiviral responses in the lung leading to protection against lethal influenza infection in mice. Antiviral Research. 92: 346-55. PMID 21945041 DOI: 10.1016/J.Antiviral.2011.09.004 |
0.42 |
|
| 2011 |
Ferreira VH, Nazli A, Khan G, Mian MF, Ashkar AA, Gray-Owen S, Kaul R, Kaushic C. Endometrial epithelial cell responses to coinfecting viral and bacterial pathogens in the genital tract can activate the HIV-1 LTR in an NF{kappa}B-and AP-1-dependent manner. The Journal of Infectious Diseases. 204: 299-308. PMID 21673042 DOI: 10.1093/Infdis/Jir260 |
0.31 |
|
| 2011 |
Mian MF, Pek EA, Chenoweth MJ, Coombes BK, Ashkar AA. Humanized mice for Salmonella typhi infection: new tools for an old problem. Virulence. 2: 248-52. PMID 21623167 DOI: 10.4161/Viru.2.3.16133 |
0.309 |
|
| 2011 |
Gillgrass A, Ashkar A. Stimulating natural killer cells to protect against cancer: recent developments. Expert Review of Clinical Immunology. 7: 367-82. PMID 21595603 DOI: 10.1586/Eci.10.102 |
0.435 |
|
| 2011 |
Gill N, Chenoweth MJ, Verdu EF, Ashkar AA. NK cells require type I IFN receptor for antiviral responses during genital HSV-2 infection. Cellular Immunology. 269: 29-37. PMID 21477795 DOI: 10.1016/J.Cellimm.2011.03.007 |
0.534 |
|
| 2011 |
Thatte A, DeWitte-Orr SJ, Lichty B, Mossman KL, Ashkar AA. A critical role for IL-15 in TLR-mediated innate antiviral immunity against genital HSV-2 infection. Immunology and Cell Biology. 89: 663-9. PMID 21339766 DOI: 10.1038/Icb.2011.7 |
0.477 |
|
| 2011 |
Chan T, Barra NG, Lee AJ, Ashkar AA. Innate and adaptive immunity against herpes simplex virus type 2 in the genital mucosa. Journal of Reproductive Immunology. 88: 210-8. PMID 21334750 DOI: 10.1016/J.Jri.2011.01.001 |
0.425 |
|
| 2011 |
Boudreau JE, Stephenson KB, Wang F, Ashkar AA, Mossman KL, Lenz LL, Rosenthal KL, Bramson JL, Lichty BD, Wan Y. IL-15 and type I interferon are required for activation of tumoricidal NK cells by virus-infected dendritic cells. Cancer Research. 71: 2497-506. PMID 21307131 DOI: 10.1158/0008-5472.Can-10-3025 |
0.449 |
|
| 2011 |
Firoz Mian M, Ashkar AA. Induction of innate immune responses in the female genital tract: friend or foe of HIV-1 infection? American Journal of Reproductive Immunology (New York, N.Y. : 1989). 65: 344-51. PMID 21223417 DOI: 10.1111/J.1600-0897.2010.00945.X |
0.327 |
|
| 2011 |
Firoz Mian M, Pek EA, Chenoweth MJ, Ashkar AA. Humanized mice are susceptible to Salmonella typhi infection. Cellular & Molecular Immunology. 8: 83-7. PMID 21200387 DOI: 10.1038/Cmi.2010.52 |
0.377 |
|
| 2011 |
Chan T, Pek EA, Huth K, Ashkar AA. CD4(+) T-cells are important in regulating macrophage polarization in C57BL/6 wild-type mice. Cellular Immunology. 266: 180-6. PMID 21040907 DOI: 10.1016/J.Cellimm.2010.10.002 |
0.426 |
|
| 2011 |
Pek EA, Chan T, Reid S, Ashkar AA. Characterization and IL-15 dependence of NK cells in humanized mice. Immunobiology. 216: 218-24. PMID 20627447 DOI: 10.1016/J.Imbio.2010.04.008 |
0.493 |
|
| 2010 |
Barra NG, Gillgrass A, Ashkar AA. Effective control of viral infections by the adaptive immune system requires assistance from innate immunity. Expert Review of Vaccines. 9: 1143-7. PMID 20923266 DOI: 10.1586/Erv.10.119 |
0.376 |
|
| 2010 |
Davies E, Reid S, Medina MF, Lichty B, Ashkar AA. IL-15 has innate anti-tumor activity independent of NK and CD8 T cells. Journal of Leukocyte Biology. 88: 529-36. PMID 20538758 DOI: 10.1189/Jlb.0909648 |
0.487 |
|
| 2010 |
Mian MF, Lauzon NM, Andrews DW, Lichty BD, Ashkar AA. FimH can directly activate human and murine natural killer cells via TLR4. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1379-88. PMID 20442710 DOI: 10.1038/Mt.2010.75 |
0.497 |
|
| 2010 |
Small CL, Shaler CR, McCormick S, Jeyanathan M, Damjanovic D, Brown EG, Arck P, Jordana M, Kaushic C, Ashkar AA, Xing Z. Influenza infection leads to increased susceptibility to subsequent bacterial superinfection by impairing NK cell responses in the lung. Journal of Immunology (Baltimore, Md. : 1950). 184: 2048-56. PMID 20083661 DOI: 10.4049/Jimmunol.0902772 |
0.435 |
|
| 2010 |
Barra NG, Reid S, MacKenzie R, Werstuck G, Trigatti BL, Richards C, Holloway AC, Ashkar AA. Interleukin-15 contributes to the regulation of murine adipose tissue and human adipocytes. Obesity (Silver Spring, Md.). 18: 1601-7. PMID 20019685 DOI: 10.1038/Oby.2009.445 |
0.379 |
|
| 2010 |
Ashkar A. Regulation of T cell responses against HSV Journal of Reproductive Immunology. 86: 23-24. DOI: 10.1016/J.Jri.2010.06.038 |
0.332 |
|
| 2010 |
Scott M, Ashkar A, Trigatti B, Richards CD. PS2-04 Oncostatin M induces interleukin-1R1, interleukin-17 receptor a and synergistic responses to IL-1 and IL-17A ligands in mouse aortic adventitial fibroblasts Cytokine. 52: 50-51. DOI: 10.1016/J.Cyto.2010.07.209 |
0.344 |
|
| 2009 |
Kwant-Mitchell A, Pek EA, Rosenthal KL, Ashkar AA. Development of functional human NK cells in an immunodeficient mouse model with the ability to provide protection against tumor challenge. Plos One. 4: e8379. PMID 20027308 DOI: 10.1371/Journal.Pone.0008379 |
0.487 |
|
| 2009 |
Kwant-Mitchell A, Ashkar AA, Rosenthal KL. Mucosal innate and adaptive immune responses against herpes simplex virus type 2 in a humanized mouse model. Journal of Virology. 83: 10664-76. PMID 19656896 DOI: 10.1128/Jvi.02584-08 |
0.433 |
|
| 2009 |
Mian MF, Pek EA, Mossman KL, Stämpfli MR, Ashkar AA. Exposure to cigarette smoke suppresses IL-15 generation and its regulatory NK cell functions in poly I:C-augmented human PBMCs. Molecular Immunology. 46: 3108-16. PMID 19592095 DOI: 10.1016/J.Molimm.2009.06.009 |
0.428 |
|
| 2009 |
Gill N, Paltser G, Ashkar AA. Interleukin-15 expression affects homeostasis and function of B cells through NK cell-derived interferon-gamma. Cellular Immunology. 258: 59-64. PMID 19361783 DOI: 10.1016/J.Cellimm.2009.03.010 |
0.484 |
|
| 2009 |
Murphy SP, Tayade C, Ashkar AA, Hatta K, Zhang J, Croy BA. Interferon gamma in successful pregnancies. Biology of Reproduction. 80: 848-59. PMID 19164174 DOI: 10.1095/Biolreprod.108.073353 |
0.639 |
|
| 2009 |
Ashkar AA, Reid S, Verdu EF, Zhang K, Coombes BK. Interleukin-15 and NK1.1+ cells provide innate protection against acute Salmonella enterica serovar Typhimurium infection in the gut and in systemic tissues. Infection and Immunity. 77: 214-22. PMID 19015253 DOI: 10.1128/Iai.01066-08 |
0.53 |
|
| 2009 |
Nazli A, Yao XD, Smieja M, Rosenthal KL, Ashkar AA, Kaushic C. Differential induction of innate anti-viral responses by TLR ligands against Herpes simplex virus, type 2, infection in primary genital epithelium of women. Antiviral Research. 81: 103-12. PMID 19013198 DOI: 10.1016/J.Antiviral.2008.10.005 |
0.339 |
|
| 2009 |
Gill N, Ashkar AA. Overexpression of interleukin-15 compromises CD4-dependent adaptive immune responses against herpes simplex virus 2. Journal of Virology. 83: 918-26. PMID 19004955 DOI: 10.1128/Jvi.01282-08 |
0.504 |
|
| 2009 |
Mian MF, Stämpfli MR, Mossman KL, Ashkar AA. Cigarette smoke attenuation of poly I:C-induced innate antiviral responses in human PBMC is mainly due to inhibition of IFN-beta production. Molecular Immunology. 46: 821-9. PMID 18930547 DOI: 10.1016/J.Molimm.2008.09.007 |
0.342 |
|
| 2008 |
Ashkar AA, Mossman KL, Coombes BK, Gyles CL, Mackenzie R. FimH adhesin of type 1 fimbriae is a potent inducer of innate antimicrobial responses which requires TLR4 and type 1 interferon signalling. Plos Pathogens. 4: e1000233. PMID 19057665 DOI: 10.1371/Journal.Ppat.1000233 |
0.421 |
|
| 2008 |
Mossman KL, Mian MF, Lauzon NM, Gyles CL, Lichty B, Mackenzie R, Gill N, Ashkar AA. Cutting edge: FimH adhesin of type 1 fimbriae is a novel TLR4 ligand. Journal of Immunology (Baltimore, Md. : 1950). 181: 6702-6. PMID 18981086 DOI: 10.4049/Jimmunol.181.10.6702 |
0.356 |
|
| 2008 |
Small CL, McCormick S, Gill N, Kugathasan K, Santosuosso M, Donaldson N, Heinrichs DE, Ashkar A, Xing Z. NK cells play a critical protective role in host defense against acute extracellular Staphylococcus aureus bacterial infection in the lung. Journal of Immunology (Baltimore, Md. : 1950). 180: 5558-68. PMID 18390740 DOI: 10.4049/Jimmunol.180.8.5558 |
0.489 |
|
| 2008 |
Gill N, Davies EJ, Ashkar AA. The role of toll-like receptor ligands/agonists in protection against genital HSV-2 infection. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 59: 35-43. PMID 18154594 DOI: 10.1111/J.1600-0897.2007.00558.X |
0.328 |
|
| 2008 |
Mian MF, Lauzon NM, Stämpfli MR, Mossman KL, Ashkar AA. Impairment of human NK cell cytotoxic activity and cytokine release by cigarette smoke. Journal of Leukocyte Biology. 83: 774-84. PMID 18055568 DOI: 10.1189/Jlb.0707481 |
0.437 |
|
| 2007 |
Lauzon NM, Mian F, Ashkar AA. Toll-like receptors, natural killer cells and innate immunity. Advances in Experimental Medicine and Biology. 598: 1-11. PMID 17892200 DOI: 10.1007/978-0-387-71767-8_1 |
0.392 |
|
| 2007 |
MacDonald EM, Savoy A, Gillgrass A, Fernandez S, Smieja M, Rosenthal KL, Ashkar AA, Kaushic C. Susceptibility of human female primary genital epithelial cells to herpes simplex virus, type-2 and the effect of TLR3 ligand and sex hormones on infection. Biology of Reproduction. 77: 1049-59. PMID 17881767 DOI: 10.1095/Biolreprod.107.063933 |
0.388 |
|
| 2007 |
Divangahi M, Yang T, Kugathasan K, McCormick S, Takenaka S, Gaschler G, Ashkar A, Stampfli M, Gauldie J, Bramson J, Takai T, Brown E, Yokoyama WM, Aoki N, Xing Z. Critical negative regulation of type 1 T cell immunity and immunopathology by signaling adaptor DAP12 during intracellular infection. Journal of Immunology (Baltimore, Md. : 1950). 179: 4015-26. PMID 17785840 DOI: 10.4049/Jimmunol.179.6.4015 |
0.446 |
|
| 2007 |
Gill N, Ashkar AA. Adaptive immune responses fail to provide protection against genital HSV-2 infection in the absence of IL-15. European Journal of Immunology. 37: 2529-38. PMID 17668897 DOI: 10.1002/Eji.200636997 |
0.48 |
|
| 2007 |
Gill N, Lauzon N, Ashkar A. The Role of IL-15 Signaling in the Induction of Innate Antiviral Responses Current Signal Transduction Therapy. 2: 180-185. DOI: 10.2174/157436207781745355 |
0.368 |
|
| 2006 |
Lauzon NM, Mian F, MacKenzie R, Ashkar AA. The direct effects of Toll-like receptor ligands on human NK cell cytokine production and cytotoxicity. Cellular Immunology. 241: 102-12. PMID 17049504 DOI: 10.1016/J.Cellimm.2006.08.004 |
0.411 |
|
| 2006 |
Gill N, Deacon PM, Lichty B, Mossman KL, Ashkar AA. Induction of innate immunity against herpes simplex virus type 2 infection via local delivery of Toll-like receptor ligands correlates with beta interferon production. Journal of Virology. 80: 9943-50. PMID 17005672 DOI: 10.1128/Jvi.01036-06 |
0.419 |
|
| 2006 |
Rad M, Ahmadi M, Hosseini RF, Ashkar AA, Nejati M, Tabaraie B, Nourozian D. Protection againstListeria monocytogenesby ODN Containing CpG Motifs in BALB/c and C57BL/6 Mice Journal of Applied Animal Research. 29: 145-147. DOI: 10.1080/09712119.2006.9706591 |
0.355 |
|
| 2006 |
Rad M, Ahmadi M, Hosseini RF, Ashkar AA, Afshari JT. The role of interleukine-12 in protection induced by CpG ODN against Listeria monocytogenes in BALB/c and C57BL/6 Comparative Haematology International. 14: 197-201. DOI: 10.1007/S00580-005-0594-Y |
0.433 |
|
| 2005 |
Albieri A, Hoshida MS, Gagioti SM, Leanza EC, Abrahamsohn I, Croy A, Ashkar AA, Bevilacqua E. Interferon-gamma alters the phagocytic activity of the mouse trophoblast. Reproductive Biology and Endocrinology : Rb&E. 3: 34. PMID 16092971 DOI: 10.1186/1477-7827-3-34 |
0.472 |
|
| 2005 |
Mossman KL, Ashkar AA. Herpesviruses and the innate immune response. Viral Immunology. 18: 267-81. PMID 16035939 DOI: 10.1089/Vim.2005.18.267 |
0.463 |
|
| 2005 |
Gill N, Rosenthal KL, Ashkar AA. NK and NKT cell-independent contribution of interleukin-15 to innate protection against mucosal viral infection. Journal of Virology. 79: 4470-8. PMID 15767447 DOI: 10.1128/Jvi.79.7.4470-4478.2005 |
0.514 |
|
| 2004 |
Ashkar AA, Yao XD, Gill N, Sajic D, Patrick AJ, Rosenthal KL. Toll-like receptor (TLR)-3, but not TLR4, agonist protects against genital herpes infection in the absence of inflammation seen with CpG DNA. The Journal of Infectious Diseases. 190: 1841-9. PMID 15499542 DOI: 10.1086/425079 |
0.316 |
|
| 2003 |
Sajic D, Ashkar AA, Patrick AJ, McCluskie MJ, Davis HL, Levine KL, Holl R, Rosenthal KL. Parameters of CpG oligodeoxynucleotide-induced protection against intravaginal HSV-2 challenge. Journal of Medical Virology. 71: 561-8. PMID 14556270 DOI: 10.1002/Jmv.10518 |
0.376 |
|
| 2003 |
Ashkar AA, Black GP, Wei Q, He H, Liang L, Head JR, Croy BA. Assessment of requirements for IL-15 and IFN regulatory factors in uterine NK cell differentiation and function during pregnancy. Journal of Immunology (Baltimore, Md. : 1950). 171: 2937-44. PMID 12960317 DOI: 10.4049/Jimmunol.171.6.2937 |
0.688 |
|
| 2003 |
Ashkar AA, Rosenthal KL. Interleukin-15 and natural killer and NKT cells play a critical role in innate protection against genital herpes simplex virus type 2 infection. Journal of Virology. 77: 10168-71. PMID 12941930 DOI: 10.1128/Jvi.77.18.10168-10171.2003 |
0.55 |
|
| 2003 |
Gillgrass AE, Ashkar AA, Rosenthal KL, Kaushic C. Prolonged exposure to progesterone prevents induction of protective mucosal responses following intravaginal immunization with attenuated herpes simplex virus type 2. Journal of Virology. 77: 9845-51. PMID 12941893 DOI: 10.1128/Jvi.77.18.9845-9851.2003 |
0.42 |
|
| 2003 |
Croy BA, Esadeg S, Chantakru S, van den Heuvel M, Paffaro VA, He H, Black GP, Ashkar AA, Kiso Y, Zhang J. Update on pathways regulating the activation of uterine Natural Killer cells, their interactions with decidual spiral arteries and homing of their precursors to the uterus. Journal of Reproductive Immunology. 59: 175-91. PMID 12896821 DOI: 10.1016/S0165-0378(03)00046-9 |
0.796 |
|
| 2003 |
Croy BA, He H, Esadeg S, Wei Q, McCartney D, Zhang J, Borzychowski A, Ashkar AA, Black GP, Evans SS, Chantakru S, van den Heuvel M, Paffaro VA, Yamada AT. Uterine natural killer cells: insights into their cellular and molecular biology from mouse modelling. Reproduction (Cambridge, England). 126: 149-60. PMID 12887272 DOI: 10.1530/Rep.0.1260149 |
0.805 |
|
| 2003 |
Ashkar AA, Bauer S, Mitchell WJ, Vieira J, Rosenthal KL. Local delivery of CpG oligodeoxynucleotides induces rapid changes in the genital mucosa and inhibits replication, but not entry, of herpes simplex virus type 2. Journal of Virology. 77: 8948-56. PMID 12885911 DOI: 10.1128/Jvi.77.16.8948-8956.2003 |
0.439 |
|
| 2003 |
Kaushic C, Ashkar AA, Reid LA, Rosenthal KL. Progesterone increases susceptibility and decreases immune responses to genital herpes infection. Journal of Virology. 77: 4558-65. PMID 12663762 DOI: 10.1128/Jvi.77.8.4558-4565.2003 |
0.408 |
|
| 2002 |
Croy BA, Chantakru S, Esadeg S, Ashkar AA, Wei Q. Decidual natural killer cells: key regulators of placental development (a review). Journal of Reproductive Immunology. 57: 151-68. PMID 12385840 DOI: 10.1016/S0165-0378(02)00005-0 |
0.783 |
|
| 2002 |
Ashkar AA, Rosenthal KL. Toll-like receptor 9, CpG DNA and innate immunity. Current Molecular Medicine. 2: 545-56. PMID 12243247 DOI: 10.2174/1566524023362159 |
0.384 |
|
| 2001 |
Ashkar AA, Croy BA. Functions of uterine natural killer cells are mediated by interferon gamma production during murine pregnancy. Seminars in Immunology. 13: 235-41. PMID 11437631 DOI: 10.1006/Smim.2000.0319 |
0.696 |
|
| 2000 |
Ashkar AA, Di Santo JP, Croy BA. Interferon gamma contributes to initiation of uterine vascular modification, decidual integrity, and uterine natural killer cell maturation during normal murine pregnancy. The Journal of Experimental Medicine. 192: 259-70. PMID 10899912 DOI: 10.1084/Jem.192.2.259 |
0.679 |
|
| 2000 |
Croy BA, Di Santo JP, Greenwood JD, Chantakru S, Ashkar AA. Transplantation into genetically alymphoid mice as an approach to dissect the roles of uterine natural killer cells during pregnancy--a review. Placenta. 21: S77-80. PMID 10831128 DOI: 10.1053/Plac.1999.0518 |
0.785 |
|
| 2000 |
Croy BA, Ashkar AA, Minhas K, Greenwood JD. Can murine uterine natural killer cells give insights into the pathogenesis of preeclampsia? Journal of the Society For Gynecologic Investigation. 7: 12-20. PMID 10732312 |
0.65 |
|
| 1999 |
Croy BA, Prudencio J, Minhas K, Ashkar AA, Galligan C, Foster RA, Buckrell B, Coomber BL. A preliminary study on the usefulness of huIL-8 in cervical relaxation of the ewe for artificial insemination and for embryo transfer. Theriogenology. 52: 271-87. PMID 10734394 DOI: 10.1016/S0093-691X(99)00128-4 |
0.531 |
|
| 1999 |
Ashkar AA, Croy BA. Interferon-gamma contributes to the normalcy of murine pregnancy. Biology of Reproduction. 61: 493-502. PMID 10411532 DOI: 10.1095/BIOLREPROD61.2.493 |
0.626 |
|
| 1997 |
Croy BA, Ashkar AA, Foster RA, DiSanto JP, Magram J, Carson D, Gendler SJ, Grusby MJ, Wagner N, Muller W, Guimond MJ. Histological studies of gene-ablated mice support important functional roles for natural killer cells in the uterus during pregnancy. Journal of Reproductive Immunology. 35: 111-33. PMID 9421796 DOI: 10.1016/S0165-0378(97)00054-5 |
0.692 |
|
| 1997 |
Croy B, Ashkar A, Foster R, Disanto J, Guimond M. Uterine leucocytes in animal species Journal of Reproductive Immunology. 34: 19-20. DOI: 10.1016/S0165-0378(97)90386-7 |
0.465 |
|
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