Year |
Citation |
Score |
2023 |
Lyu MY, Morais GN, Chen S, Brown MK. Ni-Catalyzed 1,1- and 1,3-Aminoboration of Unactivated Alkenes. Journal of the American Chemical Society. PMID 38078874 DOI: 10.1021/jacs.3c12770 |
0.324 |
|
2023 |
Nie X, Ritter CW, Hemming M, Ivlev SI, Xie X, Chen S, Meggers E. Nitrene-Mediated Enantioselective Intramolecular Olefin Oxyamination to Access Chiral γ-Aminomethyl-γ-Lactones. Angewandte Chemie (International Ed. in English). e202314398. PMID 37920926 DOI: 10.1002/anie.202314398 |
0.344 |
|
2023 |
Qian H, Cheng ZP, Luo Y, Lv L, Chen S, Li Z. Pd/IPr-Catalyzed Hydrodefluorination of -Difluorocyclopropanes: Regioselective Synthesis of Terminal Fluoroalkenes. Journal of the American Chemical Society. PMID 37830927 DOI: 10.1021/jacs.3c07992 |
0.357 |
|
2023 |
Liu DH, Nagashima K, Liang H, Yue XL, Chu YP, Chen S, Ma J. Chemoselective Quinoline and Isoquinoline Reduction by Energy Transfer Catalysis Enabled Hydrogen Atom Transfer. Angewandte Chemie (International Ed. in English). e202312203. PMID 37803457 DOI: 10.1002/anie.202312203 |
0.347 |
|
2023 |
Qian H, Nguyen HD, Lv L, Chen S, Li Z. Chemo-, Stereo- and Regioselective Fluoroallylation/Annulation of Hydrazones with gem-Difluorocyclopropanes via Tunable Palladium/NHC Catalysis. Angewandte Chemie (International Ed. in English). e202303271. PMID 37013706 DOI: 10.1002/anie.202303271 |
0.411 |
|
2022 |
Shen Z, Vargas-Rivera MA, Rigby EL, Chen S, Ellman JA. Visible Light-Mediated, Diastereoselective Epimerization of Morpholines and Piperazines to More Stable Isomers. Acs Catalysis. 12: 12860-12868. PMID 36406894 DOI: 10.1021/acscatal.2c03672 |
0.624 |
|
2022 |
Guo R, Adak S, Bellotti P, Gao X, Smith WW, Le SN, Ma J, Houk KN, Glorius F, Chen S, Brown MK. Photochemical Dearomative Cycloadditions of Quinolines and Alkenes: Scope and Mechanism Studies. Journal of the American Chemical Society. PMID 36106902 DOI: 10.1021/jacs.2c07726 |
0.38 |
|
2022 |
Ji P, Davies CC, Gao F, Chen J, Meng X, Houk KN, Chen S, Wang W. Selective skeletal editing of polycyclic arenes using organophotoredox dearomative functionalization. Nature Communications. 13: 4565. PMID 35931700 DOI: 10.1038/s41467-022-32201-7 |
0.372 |
|
2022 |
Kazerouni AM, Brandes DS, Davies CC, Cotter LF, Mayer JM, Chen S, Ellman JA. Visible Light-Mediated, Highly Diastereoselective Epimerization of Lactams from the Most Accessible to the More Stable Stereoisomer. Acs Catalysis. 12: 7798-7803. PMID 35832573 DOI: 10.1021/acscatal.2c02232 |
0.719 |
|
2021 |
Huffman BJ, Chu T, Hanaki Y, Wong J, Chen S, Houk K, Shenvi RA. Stereodivergent Attached-Ring Synthesis via Non-Covalent Interactions: A Short Formal Synthesis of Merrilactone A. Angewandte Chemie (International Ed. in English). PMID 34820990 DOI: 10.1002/anie.202114514 |
0.354 |
|
2021 |
Gao AZ, Chen S. Mechanism and Selectivities in Ru-Catalyzed Anti-Markovnikov Formal Hydroalkylation of 1,3-Dienes and Enynes: A Computational Study. The Journal of Organic Chemistry. PMID 34406774 DOI: 10.1021/acs.joc.1c01319 |
0.349 |
|
2021 |
Zhang C, Gao AZ, Nie X, Ye CX, Ivlev SI, Chen S, Meggers E. Catalytic α-Deracemization of Ketones Enabled by Photoredox Deprotonation and Enantioselective Protonation. Journal of the American Chemical Society. PMID 34392683 DOI: 10.1021/jacs.1c06637 |
0.4 |
|
2021 |
Zhang H, Novak AJE, Jamieson CS, Xue XS, Chen S, Trauner D, Houk KN. Computational Exploration of the Mechanism of Critical Steps in the Biomimetic Synthesis of Preuisolactone A, and Discovery of New Ambimodal (5 + 2)/(4 + 2) Cycloadditions. Journal of the American Chemical Society. PMID 33887906 DOI: 10.1021/jacs.1c01856 |
0.316 |
|
2021 |
Ma J, Chen S, Bellotti P, Guo R, Schäfer F, Heusler A, Zhang X, Daniliuc C, Brown MK, Houk KN, Glorius F. Photochemical intermolecular dearomative cycloaddition of bicyclic azaarenes with alkenes. Science (New York, N.Y.). 371: 1338-1345. PMID 33766881 DOI: 10.1126/science.abg0720 |
0.399 |
|
2020 |
Gieuw MH, Chen S, Ke Z, Houk KN, Yeung YY. Boron tribromide as a reagent for anti-Markovnikov addition of HBr to cyclopropanes. Chemical Science. 11: 9426-9433. PMID 34094209 DOI: 10.1039/d0sc02567d |
0.304 |
|
2020 |
Shen Z, Walker MM, Chen S, Parada GA, Chu DM, Dongbang S, Mayer JM, Houk KN, Ellman JA. General Light-Mediated, Highly Diastereoselective Piperidine Epimerization: From Most Accessible to Most Stable Stereoisomer. Journal of the American Chemical Society. PMID 33373212 DOI: 10.1021/jacs.0c11911 |
0.636 |
|
2020 |
Demoret RM, Baker MA, Ohtawa M, Chen S, Lam CC, Khom S, Roberto M, Forli S, Houk KN, Shenvi RA. Synthetic, Mechanistic and Biological Interrogation of Ginkgo biloba Chemical Space en route to (-)-Bilobalide. Journal of the American Chemical Society. PMID 32991152 DOI: 10.1021/jacs.0c08231 |
0.304 |
|
2020 |
Yamano MM, Kelleghan AV, Shao Q, Giroud M, Simmons BJ, Li B, Chen S, Houk KN, Garg NK. Intercepting fleeting cyclic allenes with asymmetric nickel catalysis. Nature. PMID 32846425 DOI: 10.1038/S41586-020-2701-2 |
0.384 |
|
2020 |
Tan Y, Chen S, Zhou Z, Hong Y, Ivlev S, Houk KN, Meggers E. Intramolecular C(sp3)-H Bond Oxygenation through Transition Metal Acylnitrenoids. Angewandte Chemie (International Ed. in English). PMID 32729945 DOI: 10.1002/Anie.202009335 |
0.335 |
|
2020 |
Ye CX, Chen S, Han F, Xie X, Ivlev S, Houk KN, Meggers E. Atroposelective Synthesis of Axially Chiral N-Arylpyrroles by Chiral-at-Rhodium Catalysis. Angewandte Chemie (International Ed. in English). PMID 32488954 DOI: 10.1002/Anie.202004799 |
0.404 |
|
2020 |
Gao L, Su C, Du X, Wang R, Chen S, Zhou Y, Liu C, Liu X, Tian R, Zhang L, Xie K, Chen S, Guo Q, Guo L, Hano Y, et al. FAD-dependent enzyme-catalysed intermolecular [4+2] cycloaddition in natural product biosynthesis. Nature Chemistry. PMID 32451436 DOI: 10.1038/S41557-020-0467-7 |
0.371 |
|
2020 |
Walker MM, Koronkiewicz B, Chen S, Houk KN, Mayer JM, Ellman JA. Highly Diastereoselective Functionalization of Piperidines by Photoredox Catalyzed α-Amino C-H Arylation and Epimerization. Journal of the American Chemical Society. PMID 32286827 DOI: 10.1021/Jacs.9B13165 |
0.628 |
|
2020 |
Huffman BJ, Chen S, Schwarz JL, Plata RE, Chin EN, Lairson LL, Houk KN, Shenvi RA. Electronic complementarity permits hindered butenolide heterodimerization and discovery of novel cGAS/STING pathway antagonists. Nature Chemistry. PMID 32042135 DOI: 10.1038/S41557-019-0413-8 |
0.309 |
|
2020 |
Chen S, Wong J, Houk KN. Mechanism of the Manolikakes Enamide-Based Domino Reaction for the Stereospecific Construction of Tetrahydropyrans. The Journal of Organic Chemistry. PMID 32017561 DOI: 10.1021/Acs.Joc.9B03440 |
0.46 |
|
2019 |
He CQ, Lam CC, Yu P, Song Z, Chen M, Lam YH, Chen S, Houk KN. Catalytic Effects of Ammonium and Sulfonium Salts and External Electric Fields on Aza-Diels-Alder Reactions. The Journal of Organic Chemistry. PMID 31891501 DOI: 10.1021/Acs.Joc.9B03446 |
0.412 |
|
2019 |
Lovett GH, Chen S, Xue XS, Houk KN, MacMillan DWC. Open-Shell Fluorination of Alkyl Bromides: Unexpected Selectivity in a Silyl Radical-Mediated Chain Process. Journal of the American Chemical Society. PMID 31774670 DOI: 10.1021/Jacs.9B11434 |
0.453 |
|
2019 |
Zhou Z, Chen S, Hong Y, Winterling E, Tan Y, Hemming M, Harms K, Houk KN, Meggers E. Non--Symmetric Chiral-at-Ruthenium Catalyst for Highly Efficient Enantioselective Intramolecular C(sp)-H Amidation. Journal of the American Chemical Society. PMID 31751132 DOI: 10.1021/Jacs.9B09301 |
0.363 |
|
2019 |
Zhang C, Chen S, Ye CX, Harms K, Zhang L, Houk KN, Meggers E. Asymmetric Photocatalysis by Intramolecular Hydrogen-Atom Transfer in Photoexcited Catalyst-Substrate Complex. Angewandte Chemie (International Ed. in English). PMID 31469211 DOI: 10.1002/Anie.201905647 |
0.438 |
|
2019 |
Zou Y, Chen S, Houk KN. Origins of Selective Formation of 5-Vinyl-2-Methylene Furans from Oxyallyl/Diene (3+2) Cycloadditions with Pd(0) Catalysis. Journal of the American Chemical Society. PMID 31328520 DOI: 10.1021/Jacs.9B05762 |
0.318 |
|
2019 |
Cai L, Zhang K, Chen S, Lepage RJ, Houk KN, Krenske EH, Kwon O. Catalytic Asymmetric Staudinger-aza-Wittig Reaction for the Synthesis of Heterocyclic Amines. Journal of the American Chemical Society. PMID 31184143 DOI: 10.1021/Jacs.9B04803 |
0.52 |
|
2018 |
Suh SE, Chen S, Houk KN, Chenoweth DM. The mechanism of the triple aryne-tetrazine reaction cascade: theory and experiment. Chemical Science. 9: 7688-7693. PMID 30542547 DOI: 10.1039/C8Sc01796D |
0.34 |
|
2018 |
Chen S, Chan AY, Walker MM, Ellman JA, Houk KN. π-Facial Selectivities in Hydride Reductions of Hindered Endocyclic Iminium Ions. The Journal of Organic Chemistry. PMID 30516383 DOI: 10.1021/Acs.Joc.8B02603 |
0.519 |
|
2018 |
Chen S, Yu P, Houk KN. Ambimodal Dipolar/Diels-Alder Cycloaddition Transition States Involving Proton Transfers. Journal of the American Chemical Society. PMID 30479123 DOI: 10.1021/Jacs.8B11080 |
0.374 |
|
2018 |
Zhou Z, Chen S, Qin J, Nie X, Zheng X, Harms K, Riedel R, Houk KN, Meggers E. Catalytic Enantioselective Intramolecular C(sp3)-H Amination of 2-Azidoacetamides. Angewandte Chemie (International Ed. in English). PMID 30475437 DOI: 10.1002/Anie.201811927 |
0.39 |
|
2018 |
Chen S, Zheng Y, Cui T, Meggers E, Houk KN. Arylketone π-Conjugation Controls Enantioselectivity in Asymmetric Alkynylations Catalyzed by Centrochiral Ruthenium Complexes. Journal of the American Chemical Society. PMID 29577723 DOI: 10.1021/Jacs.8B00485 |
0.45 |
|
2018 |
Walker MM, Chen S, Houk K, Ellman JA. Formation of Aminocyclopentadienes from Silyldihydropyridines: Ring Contractions Driven by Anion Stabilization. Angewandte Chemie (International Ed. in English). PMID 29570926 DOI: 10.1002/Anie.201800596 |
0.595 |
|
2018 |
Chen S, Houk KN. Origins of Stereoselectivity in Mannich Reactions Catalyzed by Chiral Vicinal Diamines. The Journal of Organic Chemistry. PMID 29439564 DOI: 10.1021/Acs.Joc.8B00037 |
0.464 |
|
2017 |
Chen S, Huang X, Meggers E, Houk KN. Origins of Enantioselectivity in Asymmetric Radical Additions to Octahedral Chiral-at-Rhodium Enolates: A Computational Study. Journal of the American Chemical Society. PMID 29143527 DOI: 10.1021/Jacs.7B08650 |
0.431 |
|
2017 |
He T, Ren A, Chen S, Yang Z, Yu P, Chen Y, Ding X, Shen L, Zhang H, Zou L. A theoretical study of phosphorescent Cu(I) complexes with 2-(2'quinolyl)imidazole and POP mixed ligands Organic Electronics. 45: 9-19. DOI: 10.1016/J.Orgel.2017.02.039 |
0.31 |
|
2016 |
Chen S, Bacauanu V, Knecht T, Mercado BQ, Bergman RG, Ellman JA. New Regio- and Stereoselective Cascades via Unstabilized Azomethine Ylide Cycloadditions for the Synthesis of Highly Substituted Tropane and Indolizidine Frameworks. Journal of the American Chemical Society. 138: 12664-70. PMID 27642766 DOI: 10.1021/Jacs.6B08355 |
0.645 |
|
2015 |
Neitz RJ, Bryant C, Chen S, Gut J, Hugo Caselli E, Ponce S, Chowdhury S, Xu H, Arkin MR, Ellman JA, Renslo AR. Tetrafluorophenoxymethyl ketone cruzain inhibitors with improved pharmacokinetic properties as therapeutic leads for Chagas' disease. Bioorganic & Medicinal Chemistry Letters. 25: 4834-7. PMID 26144347 DOI: 10.1016/J.Bmcl.2015.06.066 |
0.683 |
|
2015 |
Chen S, Mercado BQ, Bergman RG, Ellman JA. Regio- and Diastereoselective Synthesis of Highly Substituted, Oxygenated Piperidines from Tetrahydropyridines. The Journal of Organic Chemistry. 80: 6660-8. PMID 26098485 DOI: 10.1021/Acs.Joc.5B00816 |
0.634 |
|
2015 |
Chen S, Bergman RG, Ellman JA. Facile Rh(III)-Catalyzed Synthesis of Fluorinated Pyridines. Organic Letters. 17: 2567-9. PMID 25992591 DOI: 10.1021/Acs.Orglett.5B00979 |
0.582 |
|
2014 |
Duttwyler S, Chen S, Lu C, Mercado BQ, Bergman RG, Ellman JA. Regio- and stereoselective 1,2-dihydropyridine alkylation/addition sequence for the synthesis of piperidines with quaternary centers. Angewandte Chemie (International Ed. in English). 53: 3877-80. PMID 24604837 DOI: 10.1002/Anie.201310517 |
0.714 |
|
2013 |
Duttwyler S, Chen S, Takase MK, Wiberg KB, Bergman RG, Ellman JA. Proton donor acidity controls selectivity in nonaromatic nitrogen heterocycle synthesis. Science (New York, N.Y.). 339: 678-82. PMID 23393259 DOI: 10.1126/Science.1230704 |
0.75 |
|
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