cached image

Robert T. Kennedy - Publications

Affiliations: 
Chemistry and Pharmacology University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Nanoscale analytical techniques, chemical separations, mass spectrometry, microfluidics, neurochemistry, and islet biology
Website:
https://www.chem.lsa.umich.edu/chem/faculty/facultyDetail.php?Uniqname=rtkenn

238 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Makey DM, Diehl RC, Xin Y, Murray BE, Stoll DR, Ruotolo BT, Grinias JP, Narayan ARH, Lopez-Carillo V, Stark M, Johnen P, Kennedy RT. High-Throughput Liquid Chromatographic Analysis Using a Segmented Flow Injector with a 1 s Cycle Time. Analytical Chemistry. PMID 37943345 DOI: 10.1021/acs.analchem.3c03719  0.81
2023 D'Amico CI, Robbins G, Po I, Fang Z, Slaney TR, Tremml G, Tao L, Ruotolo BT, Kennedy RT. Screening Clones for Monoclonal Antibody Production Using Droplet Microfluidics Interfaced to Electrospray Ionization Mass Spectrometry. Journal of the American Society For Mass Spectrometry. PMID 37192521 DOI: 10.1021/jasms.3c00055  0.765
2022 Sorensen MJ, Miller KE, Jorgenson JW, Kennedy RT. Two-dimensional liquid chromatography-mass spectrometry for lipidomics using off-line coupling of hydrophilic interaction liquid chromatography with 50 cm long reversed phase capillary columns. Journal of Chromatography. A. 1687: 463707. PMID 36516490 DOI: 10.1016/j.chroma.2022.463707  0.67
2020 Bartlett MJ, Mabrouk OS, Szabò L, Flores AJ, Parent KL, Bidlack JM, Heien ML, Kennedy RT, Polt R, Sherman SJ, Falk T. The Delta-Specific Opioid Glycopeptide BBI-11008: CNS Penetration and Behavioral Analysis in a Preclinical Model of Levodopa-Induced Dyskinesia. International Journal of Molecular Sciences. 22. PMID 33374986 DOI: 10.3390/ijms22010020  0.569
2020 Valenta AC, D'Amico CI, Dugan CE, Grinias JP, Kennedy RT. A microfluidic chip for on-line derivatization and application to neurochemical monitoring. The Analyst. PMID 33346258 DOI: 10.1039/d0an01729a  0.814
2020 Arvin NE, Dawod M, Lamb DT, Anderson JP, Furtaw MD, Kennedy RT. Fast Immunoassay for Microfluidic Western Blotting by Direct Deposition of Reagents onto Capture Membrane. Analytical Methods : Advancing Methods and Applications. 12: 1606-1616. PMID 32661464 DOI: 10.1039/D0Ay00207K  0.326
2020 Wells S, Kennedy RT. High-throughput Liquid-Liquid Extractions with Nanoliter Volumes. Analytical Chemistry. PMID 31986881 DOI: 10.1021/Acs.Analchem.9B04915  0.358
2019 Holland-Moritz DA, Wismer M, Mann B, Farasat I, Guetschow E, Sun S, Moore J, Kennedy R, Mangion I, Welch CJ, Devine P. Mass Activated Droplet Sorting (MADS) Enables High Throughput Screening of Enzymatic Reactions at Nanoliter Scale. Angewandte Chemie (International Ed. in English). PMID 31868984 DOI: 10.1002/Anie.201913203  0.337
2019 Sorensen MJ, Miller KE, Jorgenson JW, Kennedy RT. Ultrahigh-Performance capillary liquid chromatography-mass spectrometry at 35 kpsi for separation of lipids. Journal of Chromatography. A. 460575. PMID 31607445 DOI: 10.1016/J.Chroma.2019.460575  0.692
2019 Wells SS, Dawod M, Kennedy RT. CE-MS with Electrokinetic Supercharging and Application to Determination of Neurotransmitters. Electrophoresis. PMID 31502303 DOI: 10.1002/Elps.201900203  0.356
2019 Ouimet CM, D'Amico CI, Kennedy RT. Droplet sample introduction to microchip gel and zone electrophoresis for rapid analysis of protein-protein complexes and enzymatic reactions. Analytical and Bioanalytical Chemistry. PMID 31300857 DOI: 10.1007/S00216-019-02006-7  0.346
2019 Steyer D, Kennedy RT. High-Throughput Nanoelectrospray Ionization-Mass Spectrometry Analysis of Microfluidic Droplet Samples. Analytical Chemistry. PMID 31033282 DOI: 10.1021/Acs.Analchem.9B00571  0.375
2019 Kawa AB, Valenta AC, Kennedy RT, Robinson TE. Incentive and Dopamine Sensitization Produced by Intermittent But Not Long Access Cocaine Self-Administration. The European Journal of Neuroscience. PMID 30968487 DOI: 10.1111/Ejn.14418  0.475
2018 Zestos AG, Carpenter CA, Kim Y, Low MJ, Kennedy RT, Gnegy ME. Ruboxistaurin reduces cocaine-stimulated increases in extracellular dopamine by modifying dopamine-autoreceptor activity. Acs Chemical Neuroscience. PMID 30384585 DOI: 10.1021/Acschemneuro.8B00259  0.764
2018 Luna-Munguia H, Zestos AG, Gliske SV, Kennedy RT, Stacey WC. Chemical biomarkers of epileptogenesis and ictogenesis in experimental epilepsy. Neurobiology of Disease. PMID 30304705 DOI: 10.1016/J.Nbd.2018.10.005  0.765
2018 Ngernsutivorakul T, Steyer D, Valenta AC, Kennedy RT. In Vivo Chemical Monitoring at High Spatiotemporal Resolution using Microfabricated Sampling Probes and Droplet-Based Microfluidics Coupled to Mass Spectrometry. Analytical Chemistry. PMID 30107117 DOI: 10.1021/Acs.Analchem.8B02468  0.398
2018 Zestos AG, Luna-Munguia H, Stacey WC, Kennedy RT. Use and Future Prospects of In Vivo Microdialysis for Epilepsy Studies. Acs Chemical Neuroscience. PMID 30001105 DOI: 10.1021/Acschemneuro.8B00271  0.771
2018 Jun H, Yu H, Gong J, Jiang J, Qiao X, Perkey E, Kim DI, Emont MP, Zestos AG, Cho JS, Liu J, Kennedy RT, Maillard I, Xu XZS, Wu J. An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling. Nature Medicine. PMID 29785025 DOI: 10.1038/S41591-018-0032-8  0.767
2018 Lu S, Dugan CE, Kennedy RT. A Microfluidic Chip with Integrated Electrophoretic Immunoassay for Investigating Cell-Cell Interactions. Analytical Chemistry. PMID 29578696 DOI: 10.1021/Acs.Analchem.7B05304  0.344
2018 Ouimet CM, Dawod M, Grinias J, Assimon VA, Lodge J, Mapp AK, Gestwicki JE, Kennedy RT. Protein cross-linking capillary electrophoresis at increased throughput for a range of protein-protein interactions. The Analyst. PMID 29565056 DOI: 10.1039/C7An02098H  0.775
2018 Ngernsutivorakul T, White TS, Kennedy RT. Microfabricated Probes for Studying Brain Chemistry: A Review. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. PMID 29405568 DOI: 10.1002/Cphc.201701180  0.319
2017 Grinias JP, Kennedy RT. Pushing the boundaries of chromatography and electrophoresis-Honoring James Jorgenson on his 65th birthday. Journal of Chromatography. A. PMID 28823782 DOI: 10.1016/J.Chroma.2017.08.027  0.762
2017 Malec PA, Oteri M, Inferrera V, Cacciola F, Mondello L, Kennedy RT. Determination of amines and phenolic acids in wine with benzoyl chloride derivatization and liquid chromatography-mass spectrometry. Journal of Chromatography. A. PMID 28774711 DOI: 10.1016/J.Chroma.2017.07.061  0.359
2017 Zestos AG, Kennedy RT. Microdialysis Coupled with LC-MS/MS for In Vivo Neurochemical Monitoring. The Aaps Journal. PMID 28660399 DOI: 10.1208/S12248-017-0114-4  0.797
2017 Carpenter C, Zestos AG, Altshuler R, Sorenson RJ, Guptaroy B, Showalter HD, Kennedy RT, Jutkiewicz E, Gnegy ME. Direct and Systemic Administration of a CNS-Permeant Tamoxifen Analog Reduces Amphetamine-Induced Dopamine Release and Reinforcing Effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28492278 DOI: 10.1038/Npp.2017.95  0.773
2017 Lu S, Kennedy RT. Using Electrophoretic Immunoassay to Monitor Hormone Secretion. Methods in Molecular Biology (Clifton, N.J.). 1547: 57-67. PMID 28044287 DOI: 10.1007/978-1-4939-6734-6_5  0.333
2017 Carpenter CA, Altshuler R, Zestos A, Sorenson R, Jutkiewicz EM, Kennedy R, Showalter H, Gnegy M. New generation tamoxifen analogs as potential treatments for amphetamine abuse Drug and Alcohol Dependence. 171: e35. DOI: 10.1016/J.Drugalcdep.2016.08.110  0.752
2016 Schmudlach A, Felton J, Kennedy RT, Dovichi NJ. Bottom-up proteomics analysis of the secretome of murine islets of Langerhans in elevated glucose levels. The Analyst. PMID 27966681 DOI: 10.1039/C6An02268E  0.304
2016 Dugan CE, Grinias JP, Parlee SD, El-Azzouny M, Evans CR, Kennedy RT. Monitoring cell secretions on microfluidic chips using solid-phase extraction with mass spectrometry. Analytical and Bioanalytical Chemistry. PMID 27761614 DOI: 10.1007/S00216-016-9983-0  0.812
2016 El Azzouny M, Longacre MJ, Ansari IU, Kennedy RT, Burant CF, MacDonald MJ. Knockdown of ATP citrate lyase in pancreatic beta cells does not inhibit insulin secretion or glucose flux and implicates the acetoacetate pathway in insulin secretion. Molecular Metabolism. 5: 980-7. PMID 27689010 DOI: 10.1016/J.Molmet.2016.07.011  0.302
2016 Sun S, Buer BC, Marsh EN, Kennedy RT. A Label-free Sirtuin 1 Assay based on Droplet-Electrospray Ionization Mass Spectrometry. Analytical Methods : Advancing Methods and Applications. 8: 3458-3465. PMID 27482292 DOI: 10.1039/C6Ay00698A  0.36
2016 Grinias JP, Wong JT, Kennedy RT. Repeatability of gradient UHPLC-MS/MS methods in instrument-controlled thermal environments. Journal of Chromatography. A. PMID 27457561 DOI: 10.1016/J.Chroma.2016.07.043  0.791
2016 Grinias JP, Whitfield JT, Guetschow ED, Kennedy RT. An Inexpensive, Open-Source USB Arduino Data Acquisition Device for Chemical Instrumentation. Journal of Chemical Education. 93: 1316-1319. PMID 27453587 DOI: 10.1021/Acs.Jchemed.6B00262  0.769
2016 Grinias JP, Kennedy RT. Advances in and prospects of microchip liquid chromatography. Trends in Analytical Chemistry : Trac. 81: 110-117. PMID 27418710 DOI: 10.1016/J.Trac.2015.08.002  0.783
2016 Jin S, Furtaw MD, Chen H, Lamb DT, Ferguson SA, Arvin N, Dawod M, Kennedy RT. Multiplexed Western Blotting Using Microchip Electrophoresis. Analytical Chemistry. PMID 27270033 DOI: 10.1021/Acs.Analchem.6B00705  0.34
2016 Wong JT, Malec PA, Mabrouk OS, Ro J, Dus M, Kennedy RT. Benzoyl chloride derivatization with liquid chromatography-mass spectrometry for targeted metabolomics of neurochemicals in biological samples. Journal of Chromatography. A. PMID 27083258 DOI: 10.1016/J.Chroma.2016.04.006  0.365
2016 Zestos AG, Mikelman SR, Kennedy RT, Gnegy ME. PKCβ inhibitors attenuate amphetamine-stimulated dopamine efflux. Acs Chemical Neuroscience. PMID 26996926 DOI: 10.1021/Acschemneuro.6B00028  0.775
2016 Karra S, Griffith WP, Kennedy RT, Gorski W. Hormone glucagon: electrooxidation and determination at carbon nanotubes. The Analyst. PMID 26937496 DOI: 10.1039/C5An02636A  0.315
2016 Lee WH, Ngernsutivorakul T, Mabrouk OS, Wong JT, Dugan CE, Pappas SS, Yoon HJ, Kennedy RT. Microfabrication and in Vivo Performance of a Microdialysis Probe with Embedded Membrane. Analytical Chemistry. PMID 26727611 DOI: 10.1021/Acs.Analchem.5B03541  0.349
2015 Grinias JP, Kennedy RT. Evaluation of 5 µm Superficially Porous Particles for Capillary and Microfluidic LC Columns. Chromatography (Basel). 2: 502-514. PMID 26714261 DOI: 10.3390/Chromatography2030502  0.775
2015 Glynn E, Thompson B, Vadrevu S, Lu S, Kennedy RT, Ha J, Sherman A, Satin LS. Chronic glucose exposure systematically shifts the oscillatory threshold of mouse islets: Experimental evidence for an early intrinsic mechanism of compensation for hyperglycemia. Endocrinology. en20151563. PMID 26697721 DOI: 10.1210/En.2015-1563  0.309
2015 Zhu S, Larkin D, Lu S, Inouye C, Haataja L, Anjum A, Kennedy R, Castle D, Arvan P. Monitoring C-peptide Storage and Secretion in Islet Beta Cells in vitro and in vivo. Diabetes. PMID 26647386 DOI: 10.2337/Db15-1264  0.327
2015 Guetschow ED, Kumar S, Lombard DB, Kennedy RT. Identification of sirtuin 5 inhibitors by ultrafast microchip electrophoresis using nanoliter volume samples. Analytical and Bioanalytical Chemistry. PMID 26635020 DOI: 10.1007/S00216-015-9206-0  0.35
2015 Zhou Y, Wong JM, Mabrouk OS, Kennedy RT. Reducing Adsorption To Improve Recovery and in Vivo Detection of Neuropeptides by Microdialysis with LC-MS. Analytical Chemistry. 87: 9802-9. PMID 26351736 DOI: 10.1021/Acs.Analchem.5B02086  0.348
2015 ElAzzouny MA, Evans CR, Burant CF, Kennedy RT. Metabolomics Analysis Reveals that AICAR Affects Glycerolipid, Ceramide and Nucleotide Synthesis Pathways in INS-1 Cells. Plos One. 10: e0129029. PMID 26107620 DOI: 10.1371/Journal.Pone.0129029  0.308
2015 Sweedler JV, Armstrong DW, Baba Y, Desmet G, Dovichi N, Ewing A, Fenselau CC, Kennedy RT, Larive CK, Ligler FS, McCreery RL, Niessner R, Pemberton JE, Tan W, Walt DR, et al. The Scope of Analytical Chemistry. Analytical Chemistry. 87: 6425. PMID 26086069 DOI: 10.1021/Acs.Analchem.5B02231  0.475
2015 Grinias JP, Kennedy RT. Advances in and prospects of microchip liquid chromatography Trac - Trends in Analytical Chemistry. DOI: 10.1016/j.trac.2015.08.002  0.777
2014 Guetschow ED, Steyer DJ, Kennedy RT. Subsecond electrophoretic separations from droplet samples for screening of enzyme modulators. Analytical Chemistry. 86: 10373-9. PMID 25233947 DOI: 10.1021/Ac502758H  0.343
2014 Sun S, Kennedy RT. Droplet electrospray ionization mass spectrometry for high throughput screening for enzyme inhibitors. Analytical Chemistry. 86: 9309-14. PMID 25137241 DOI: 10.1021/Ac502542Z  0.335
2014 Dugan CE, Cawthorn WP, MacDougald OA, Kennedy RT. Multiplexed microfluidic enzyme assays for simultaneous detection of lipolysis products from adipocytes. Analytical and Bioanalytical Chemistry. 406: 4851-9. PMID 24880873 DOI: 10.1007/S00216-014-7894-5  0.36
2014 El-Azzouny M, Evans CR, Treutelaar MK, Kennedy RT, Burant CF. Increased glucose metabolism and glycerolipid formation by fatty acids and GPR40 receptor signaling underlies the fatty acid potentiation of insulin secretion. The Journal of Biological Chemistry. 289: 13575-88. PMID 24675078 DOI: 10.1074/Jbc.M113.531970  0.3
2014 Dugan CE, Kennedy RT. Measurement of lipolysis products secreted by 3T3-L1 adipocytes using microfluidics. Methods in Enzymology. 538: 195-209. PMID 24529440 DOI: 10.1016/B978-0-12-800280-3.00011-6  0.345
2014 Jin S, Kennedy RT. New developments in Western blot technology Chinese Chemical Letters. DOI: 10.1016/J.Cclet.2015.01.021  0.316
2013 Nie J, Kennedy RT. Capillary liquid chromatography fraction collection and postcolumn reaction using segmented flow microfluidics. Journal of Separation Science. 36: 3471-7. PMID 24039151 DOI: 10.1002/Jssc.201300725  0.324
2013 Novotny MV, Kennedy RT. Editorial overview. Current Opinion in Chemical Biology. 17: 776-8. PMID 24018167 DOI: 10.1016/j.cbpa.2013.08.010  0.325
2013 Jin S, Anderson GJ, Kennedy RT. Western blotting using microchip electrophoresis interfaced to a protein capture membrane. Analytical Chemistry. 85: 6073-9. PMID 23672369 DOI: 10.1021/Ac400940X  0.34
2013 Zhou Y, Mabrouk OS, Kennedy RT. Rapid preconcentration for liquid chromatography-mass spectrometry assay of trace level neuropeptides. Journal of the American Society For Mass Spectrometry. 24: 1700-9. PMID 23592077 DOI: 10.1007/S13361-013-0605-1  0.407
2013 Lee WH, Slaney TR, Hower RW, Kennedy RT. Microfabricated sampling probes for in vivo monitoring of neurotransmitters. Analytical Chemistry. 85: 3828-31. PMID 23547793 DOI: 10.1021/Ac400579X  0.779
2013 Akiyama M, Liew CW, Lu S, Hu J, Martinez R, Hambro B, Kennedy RT, Kulkarni RN. X-box binding protein 1 is essential for insulin regulation of pancreatic α-cell function. Diabetes. 62: 2439-49. PMID 23493568 DOI: 10.2337/Db12-1747  0.306
2013 Lorenz MA, El Azzouny MA, Kennedy RT, Burant CF. Metabolome response to glucose in the β-cell line INS-1 832/13. The Journal of Biological Chemistry. 288: 10923-35. PMID 23426361 DOI: 10.1074/Jbc.M112.414961  0.734
2013 Slaney TR, Mabrouk OS, Porter-Stransky KA, Aragona BJ, Kennedy RT. Chemical gradients within brain extracellular space measured using low flow push-pull perfusion sampling in vivo. Acs Chemical Neuroscience. 4: 321-9. PMID 23421683 DOI: 10.1021/Cn300158P  0.764
2013 Hershey ND, Kennedy RT. In vivo calibration of microdialysis using infusion of stable-isotope labeled neurotransmitters. Acs Chemical Neuroscience. 4: 729-36. PMID 23374073 DOI: 10.1021/Cn300199M  0.306
2012 Mabrouk OS, Kennedy RT. Simultaneous oxytocin and arg-vasopressin measurements in microdialysates using capillary liquid chromatography-mass spectrometry. Journal of Neuroscience Methods. 209: 127-33. PMID 22710285 DOI: 10.1016/J.Jneumeth.2012.06.006  0.369
2012 Sun S, Slaney TR, Kennedy RT. Label free screening of enzyme inhibitors at femtomole scale using segmented flow electrospray ionization mass spectrometry. Analytical Chemistry. 84: 5794-800. PMID 22656268 DOI: 10.1021/Ac3011389  0.778
2012 Song P, Hershey ND, Mabrouk OS, Slaney TR, Kennedy RT. Mass spectrometry "sensor" for in vivo acetylcholine monitoring. Analytical Chemistry. 84: 4659-64. PMID 22616788 DOI: 10.1021/Ac301203M  0.781
2012 Morioka T, Dishinger JF, Reid KR, Liew CW, Zhang T, Inaba M, Kennedy RT, Kulkarni RN. Enhanced GLP-1- and sulfonylurea-induced insulin secretion in islets lacking leptin signaling. Molecular Endocrinology (Baltimore, Md.). 26: 967-76. PMID 22474124 DOI: 10.1210/Me.2011-1306  0.787
2012 Payeur AL, Lorenz MA, Kennedy RT. Analysis of fatty acid composition in insulin secreting cells by comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 893: 187-92. PMID 22456534 DOI: 10.1016/J.Jchromb.2012.03.003  0.731
2012 Shackman JG, Reid KR, Dugan CE, Kennedy RT. Dynamic monitoring of glucagon secretion from living cells on a microfluidic chip. Analytical and Bioanalytical Chemistry. 402: 2797-803. PMID 22286080 DOI: 10.1007/S00216-012-5755-7  0.815
2012 Song P, Mabrouk OS, Hershey ND, Kennedy RT. In vivo neurochemical monitoring using benzoyl chloride derivatization and liquid chromatography-mass spectrometry. Analytical Chemistry. 84: 412-9. PMID 22118158 DOI: 10.1021/Ac202794Q  0.39
2011 Slaney TR, Nie J, Hershey ND, Thwar PK, Linderman J, Burns MA, Kennedy RT. Push-pull perfusion sampling with segmented flow for high temporal and spatial resolution in vivo chemical monitoring. Analytical Chemistry. 83: 5207-13. PMID 21604670 DOI: 10.1021/Ac2003938  0.782
2011 Wang M, Hershey ND, Mabrouk OS, Kennedy RT. Collection, storage, and electrophoretic analysis of nanoliter microdialysis samples collected from awake animals in vivo. Analytical and Bioanalytical Chemistry. 400: 2013-23. PMID 21465093 DOI: 10.1007/S00216-011-4956-9  0.434
2011 Lorenz MA, Burant CF, Kennedy RT. Reducing time and increasing sensitivity in sample preparation for adherent mammalian cell metabolomics. Analytical Chemistry. 83: 3406-14. PMID 21456517 DOI: 10.1021/Ac103313X  0.758
2011 Anderson GJ, M Cipolla C, Kennedy RT. Western blotting using capillary electrophoresis. Analytical Chemistry. 83: 1350-5. PMID 21265514 DOI: 10.1021/Ac102671N  0.334
2010 Chisolm CN, Evans CR, Jennings C, Black WA, Antosz FJ, Qiang Y, Diaz AR, Kennedy RT. Development and characterization of "push-pull" sampling device with fast reaction quenching coupled to high-performance liquid chromatography for pharmaceutical process analytical technologies. Journal of Chromatography. A. 1217: 7471-7. PMID 20970142 DOI: 10.1016/J.Chroma.2010.09.066  0.79
2010 Pei J, Nie J, Kennedy RT. Parallel electrophoretic analysis of segmented samples on chip for high-throughput determination of enzyme activities. Analytical Chemistry. 82: 9261-7. PMID 20949899 DOI: 10.1021/Ac101755Y  0.362
2010 Nie J, Kennedy RT. Sampling from nanoliter plugs via asymmetrical splitting of segmented flow. Analytical Chemistry. 82: 7852-6. PMID 20738106 DOI: 10.1021/Ac101723X  0.327
2010 Clark AM, Sousa KM, Chisolm CN, MacDougald OA, Kennedy RT. Reversibly sealed multilayer microfluidic device for integrated cell perfusion and on-line chemical analysis of cultured adipocyte secretions. Analytical and Bioanalytical Chemistry. 397: 2939-47. PMID 20549489 DOI: 10.1007/S00216-010-3897-Z  0.787
2010 Li Q, Pei J, Song P, Kennedy RT. Fraction collection from capillary liquid chromatography and off-line electrospray ionization mass spectrometry using oil segmented flow. Analytical Chemistry. 82: 5260-7. PMID 20491430 DOI: 10.1021/Ac100669Z  0.343
2010 Wang M, Slaney T, Mabrouk O, Kennedy RT. Collection of nanoliter microdialysate fractions in plugs for off-line in vivo chemical monitoring with up to 2 s temporal resolution. Journal of Neuroscience Methods. 190: 39-48. PMID 20447417 DOI: 10.1016/J.Jneumeth.2010.04.023  0.801
2010 Perry ML, Leinninger GM, Chen R, Luderman KD, Yang H, Gnegy ME, Myers MG, Kennedy RT. Leptin promotes dopamine transporter and tyrosine hydroxylase activity in the nucleus accumbens of Sprague-Dawley rats. Journal of Neurochemistry. 114: 666-74. PMID 20412389 DOI: 10.1111/J.1471-4159.2010.06757.X  0.538
2010 Pei J, Li Q, Kennedy RT. Rapid and label-free screening of enzyme inhibitors using segmented flow electrospray ionization mass spectrometry. Journal of the American Society For Mass Spectrometry. 21: 1107-13. PMID 20219390 DOI: 10.1016/J.Jasms.2010.02.013  0.365
2009 Nunemaker CS, Dishinger JF, Dula SB, Wu R, Merrins MJ, Reid KR, Sherman A, Kennedy RT, Satin LS. Glucose metabolism, islet architecture, and genetic homogeneity in imprinting of [Ca2+](i) and insulin rhythms in mouse islets. Plos One. 4: e8428. PMID 20037650 DOI: 10.1371/Journal.Pone.0008428  0.782
2009 Wang M, Roman GT, Perry ML, Kennedy RT. Microfluidic chip for high efficiency electrophoretic analysis of segmented flow from a microdialysis probe and in vivo chemical monitoring. Analytical Chemistry. 81: 9072-8. PMID 19803495 DOI: 10.1021/Ac901731V  0.627
2009 Perry M, Li Q, Kennedy RT. Review of recent advances in analytical techniques for the determination of neurotransmitters. Analytica Chimica Acta. 653: 1-22. PMID 19800472 DOI: 10.1016/J.Aca.2009.08.038  0.594
2009 Reid KR, Kennedy RT. Continuous operation of microfabricated electrophoresis devices for 24 hours and application to chemical monitoring of living cells. Analytical Chemistry. 81: 6837-42. PMID 19621896 DOI: 10.1021/Ac901114K  0.723
2009 Pei J, Li Q, Lee MS, Valaskovic GA, Kennedy RT. Analysis of samples stored as individual plugs in a capillary by electrospray ionization mass spectrometry. Analytical Chemistry. 81: 6558-61. PMID 19555052 DOI: 10.1021/Ac901172A  0.364
2009 Dishinger JF, Reid KR, Kennedy RT. Quantitative monitoring of insulin secretion from single islets of Langerhans in parallel on a microfluidic chip. Analytical Chemistry. 81: 3119-27. PMID 19364142 DOI: 10.1021/Ac900109T  0.79
2009 Clark AM, Sousa KM, Jennings C, MacDougald OA, Kennedy RT. Continuous-flow enzyme assay on a microfluidic chip for monitoring glycerol secretion from cultured adipocytes. Analytical Chemistry. 81: 2350-6. PMID 19231843 DOI: 10.1021/Ac8026965  0.367
2009 Schultz KN, von Esenwein SA, Hu M, Bennett AL, Kennedy RT, Musatov S, Toran-Allerand CD, Kaplitt MG, Young LJ, Becker JB. Viral vector-mediated overexpression of estrogen receptor-alpha in striatum enhances the estradiol-induced motor activity in female rats and estradiol-modulated GABA release. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1897-903. PMID 19211896 DOI: 10.1523/Jneurosci.4647-08.2009  0.752
2009 Li Q, Zubieta JK, Kennedy RT. Practical aspects of in vivo detection of neuropeptides by microdialysis coupled off-line to capillary LC with multistage MS. Analytical Chemistry. 81: 2242-50. PMID 19196160 DOI: 10.1021/Ac802391B  0.387
2009 Yang P, Mao Y, Lee AW, Kennedy RT. Measurement of dissociation rate of biomolecular complexes using CE. Electrophoresis. 30: 457-64. PMID 19148904 DOI: 10.1002/Elps.200800397  0.502
2009 Reid KR, Burant CF, Kennedy RT. Capillary LC-MS for high sensitivity metabolomic analysis of single islets of Langerhans (Analytical Chemistry (2008) 80, (3539-3546)) Analytical Chemistry. 81: 9201. DOI: 10.1021/Ac9019363  0.709
2009 Hartman K, Brender JR, Reid KR, Smith PE, Nanga RP, Cavitt MA, Lee EL, Steel DG, Gafni A, Kennedy RT, Ramamoorthy A. A Single Mutation in the Non-Amyloidogenic Region of IAPP Greatly Reduces Toxicity Biophysical Journal. 96: 92a. DOI: 10.1016/J.Bpj.2008.12.383  0.715
2008 Schultz KN, Kennedy RT. Time-resolved microdialysis for in vivo neurochemical measurements and other applications. Annual Review of Analytical Chemistry (Palo Alto, Calif.). 1: 627-61. PMID 20636092 DOI: 10.1146/Annurev.Anchem.1.031207.113047  0.78
2008 Brender JR, Hartman K, Reid KR, Kennedy RT, Ramamoorthy A. A single mutation in the nonamyloidogenic region of islet amyloid polypeptide greatly reduces toxicity. Biochemistry. 47: 12680-8. PMID 18989933 DOI: 10.1021/Bi801427C  0.72
2008 Furchak JR, Yang P, Jennings C, Walter NG, Kennedy RT. Assay for glucosamine 6-phosphate using a ligand-activated ribozyme with fluorescence resonance energy transfer or CE-laser-induced fluorescence detection. Analytical Chemistry. 80: 8195-201. PMID 18842060 DOI: 10.1021/Ac801410K  0.789
2008 Roman GT, Wang M, Shultz KN, Jennings C, Kennedy RT. Sampling and electrophoretic analysis of segmented flow streams using virtual walls in a microfluidic device. Analytical Chemistry. 80: 8231-8. PMID 18831564 DOI: 10.1021/Ac801317T  0.403
2008 Dishinger JF, Kennedy RT. Multiplexed detection and applications for separations on parallel microchips. Electrophoresis. 29: 3296-305. PMID 18702055 DOI: 10.1002/Elps.200800067  0.778
2008 Zhang H, Saha J, Byun J, Schin M, Lorenz M, Kennedy RT, Kretzler M, Feldman EL, Pennathur S, Brosius FC. Rosiglitazone reduces renal and plasma markers of oxidative injury and reverses urinary metabolite abnormalities in the amelioration of diabetic nephropathy. American Journal of Physiology. Renal Physiology. 295: F1071-81. PMID 18667486 DOI: 10.1152/Ajprenal.90208.2008  0.699
2008 Chen H, Gu W, Cellar N, Kennedy R, Takayama S, Meiners JC. Electromechanical properties of pressure-actuated poly(dimethylsiloxane) microfluidic push-down valves. Analytical Chemistry. 80: 6110-3. PMID 18576665 DOI: 10.1021/Ac800506N  0.767
2008 Wang M, Roman GT, Schultz K, Jennings C, Kennedy RT. Improved temporal resolution for in vivo microdialysis by using segmented flow. Analytical Chemistry. 80: 5607-15. PMID 18547059 DOI: 10.1021/Ac800622S  0.793
2008 Yang P, Kennedy RT. High performance liquid chromatography coupled on-line to capillary electrophoresis with laser-induced fluorescence detection for detecting inhibitors of Src homology 2 domain-phosphopeptide binding in mixtures. Journal of Chromatography. A. 1194: 225-30. PMID 18495135 DOI: 10.1016/J.Chroma.2008.04.072  0.549
2008 Pei J, Dishinger JF, Roman DL, Rungwanitcha C, Neubig RR, Kennedy RT. Microfabricated channel array electrophoresis for characterization and screening of enzymes using RGS-G protein interactions as a model system. Analytical Chemistry. 80: 5225-31. PMID 18465881 DOI: 10.1021/Ac800553G  0.773
2008 Ni Q, Reid KR, Burant CF, Kennedy RT. Capillary LC-MS for high sensitivity metabolomic analysis of single islets of Langerhans. Analytical Chemistry. 80: 3539-46. PMID 18399659 DOI: 10.1021/Ac800406F  0.738
2008 Ferrario CR, Shou M, Samaha AN, Watson CJ, Kennedy RT, Robinson TE. The rate of intravenous cocaine administration alters c-fos mRNA expression and the temporal dynamics of dopamine, but not glutamate, overflow in the striatum. Brain Research. 1209: 151-6. PMID 18396266 DOI: 10.1016/J.Brainres.2008.02.081  0.71
2008 Miller BR, Dorner JL, Shou M, Sari Y, Barton SJ, Sengelaub DR, Kennedy RT, Rebec GV. Up-regulation of GLT1 expression increases glutamate uptake and attenuates the Huntington's disease phenotype in the R6/2 mouse. Neuroscience. 153: 329-37. PMID 18353560 DOI: 10.1016/J.Neuroscience.2008.02.004  0.539
2007 Edwards JL, Edwards RL, Reid KR, Kennedy RT. Effect of decreasing column inner diameter and use of off-line two-dimensional chromatography on metabolite detection in complex mixtures. Journal of Chromatography. A. 1172: 127-34. PMID 17961581 DOI: 10.1016/J.Chroma.2007.09.075  0.774
2007 Morioka T, Asilmaz E, Hu J, Dishinger JF, Kurpad AJ, Elias CF, Li H, Elmquist JK, Kennedy RT, Kulkarni RN. Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice. The Journal of Clinical Investigation. 117: 2860-8. PMID 17909627 DOI: 10.1172/Jci30910  0.773
2007 Cunliffe JM, Sunahara RK, Kennedy RT. Detection of g protein coupled receptor mediated adenylyl cyclase activity by capillary electrophoresis using fluorescently labeled ATP. Analytical Chemistry. 79: 7534-9. PMID 17718540 DOI: 10.1021/Ac071203+  0.754
2007 Roman GT, Kennedy RT. Fully integrated microfluidic separations systems for biochemical analysis. Journal of Chromatography. A. 1168: 170-88; discussion 1. PMID 17659293 DOI: 10.1016/J.Chroma.2007.06.010  0.306
2007 Vadakkadathmeethal K, Cunliffe JM, Swift J, Kennedy RT, Neubig RR, Sunahara RK. Fluorescence-based adenylyl cyclase assay adaptable to high throughput screening. Combinatorial Chemistry & High Throughput Screening. 10: 289-98. PMID 17506713 DOI: 10.2174/138620707780636600  0.731
2007 Cunliffe JM, Whorton MR, Sunahara RK, Kennedy RT. A CE assay for the detection of agonist-stimulated adenylyl cyclase activity. Electrophoresis. 28: 1913-20. PMID 17480040 DOI: 10.1002/Elps.200600571  0.747
2007 Yang P, Whelan RJ, Mao Y, Lee AW, Carter-Su C, Kennedy RT. Multiplexed detection of protein-peptide interaction and inhibition using capillary electrophoresis. Analytical Chemistry. 79: 1690-5. PMID 17297974 DOI: 10.1021/Ac061936E  0.508
2007 Jameson EE, Pei J, Wade SM, Neubig RR, Milligan G, Kennedy RT. Capillary electrophoresis assay for G protein-coupled receptor-mediated GTPase activity. Analytical Chemistry. 79: 1158-63. PMID 17263349 DOI: 10.1021/Ac061099G  0.684
2007 Dishinger JF, Kennedy RT. Serial immunoassays in parallel on a microfluidic chip for monitoring hormone secretion from living cells. Analytical Chemistry. 79: 947-54. PMID 17263320 DOI: 10.1021/Ac061425S  0.798
2007 Pissios P, Ozcan U, Kokkotou E, Okada T, Liew CW, Liu S, Peters JN, Dahlgren G, Karamchandani J, Kudva YC, Kurpad AJ, Kennedy RT, Maratos-Flier E, Kulkarni RN. Melanin concentrating hormone is a novel regulator of islet function and growth. Diabetes. 56: 311-9. PMID 17259374 DOI: 10.2337/Db06-0708  0.78
2007 Shackman HM, Shou M, Cellar NA, Watson CJ, Kennedy RT. Microdialysis coupled on-line to capillary liquid chromatography with tandem mass spectrometry for monitoring acetylcholine in vivo. Journal of Neuroscience Methods. 159: 86-92. PMID 16876256 DOI: 10.1016/J.Jneumeth.2006.06.020  0.804
2006 Shou M, Ferrario CR, Schultz KN, Robinson TE, Kennedy RT. Monitoring dopamine in vivo by microdialysis sampling and on-line CE-laser-induced fluorescence. Analytical Chemistry. 78: 6717-25. PMID 17007489 DOI: 10.1021/Ac0608218  0.8
2006 Cellar NA, Kennedy RT. A capillary-PDMS hybrid chip for separations-based sensing of neurotransmitters in vivo. Lab On a Chip. 6: 1205-12. PMID 16929400 DOI: 10.1039/B603561B  0.809
2006 Venton BJ, Robinson TE, Kennedy RT, Maren S. Dynamic amino acid increases in the basolateral amygdala during acquisition and expression of conditioned fear. The European Journal of Neuroscience. 23: 3391-8. PMID 16820029 DOI: 10.1111/J.1460-9568.2006.04841.X  0.74
2006 Wei H, Nolkrantz K, Parkin MC, Chisolm CN, O'Callaghan JP, Kennedy RT. Identification and quantification of neuropeptides in brain tissue by capillary liquid chromatography coupled off-line to MALDI-TOF and MALDI-TOF/TOF-MS. Analytical Chemistry. 78: 4342-51. PMID 16808441 DOI: 10.1021/Ac052196X  0.801
2006 Ueki K, Okada T, Hu J, Liew CW, Assmann A, Dahlgren GM, Peters JL, Shackman JG, Zhang M, Artner I, Satin LS, Stein R, Holzenberger M, Kennedy RT, Kahn CR, et al. Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes. Nature Genetics. 38: 583-8. PMID 16642022 DOI: 10.1038/Ng1787  0.776
2006 Watson CJ, Venton BJ, Kennedy RT. In vivo measurements of neurotransmitters by microdialysis sampling. Analytical Chemistry. 78: 1391-9. PMID 16570388 DOI: 10.1021/Ac0693722  0.736
2006 Cunliffe JM, Sunahara RK, Kennedy RT. Detection of adenylyl cyclase activity using a fluorescent ATP substrate and capillary electrophoresis. Analytical Chemistry. 78: 1731-8. PMID 16536404 DOI: 10.1021/Ac0521201  0.75
2006 Edwards JL, Chisolm CN, Shackman JG, Kennedy RT. Negative mode sheathless capillary electrophoresis electrospray ionization-mass spectrometry for metabolite analysis of prokaryotes. Journal of Chromatography. A. 1106: 80-8. PMID 16443454 DOI: 10.1016/J.Chroma.2005.08.082  0.796
2006 Hu M, Watson CJ, Kennedy RT, Becker JB. Estradiol attenuates the K+-induced increase in extracellular GABA in rat striatum. Synapse (New York, N.Y.). 59: 122-4. PMID 16320305 DOI: 10.1002/Syn.20221  0.476
2006 Venton BJ, Robinson TE, Kennedy RT. Transient changes in nucleus accumbens amino acid concentrations correlate with individual responsivity to the predator fox odor 2,5-dihydro-2,4,5-trimethylthiazoline. Journal of Neurochemistry. 96: 236-46. PMID 16300631 DOI: 10.1111/J.1471-4159.2005.03549.X  0.746
2006 Kennedy RT. Chapter 3.4 In vivo peptidomics: discovery and monitoring of neuropeptides using microdialysis and liquid chromatography with mass spectrometry Handbook of Behavioral Neuroscience. 16: 279-295. DOI: 10.1016/S1569-7339(06)16016-6  0.365
2005 Sandlin ZD, Shou M, Shackman JG, Kennedy RT. Microfluidic electrophoresis chip coupled to microdialysis for in vivo monitoring of amino acid neurotransmitters. Analytical Chemistry. 77: 7702-8. PMID 16316179 DOI: 10.1021/Ac051044Z  0.797
2005 Cellar NA, Burns ST, Meiners JC, Chen H, Kennedy RT. Microfluidic chip for low-flow push-pull perfusion sampling in vivo with on-line analysis of amino acids. Analytical Chemistry. 77: 7067-73. PMID 16255611 DOI: 10.1021/Ac0510033  0.81
2005 Wei H, Dean SL, Parkin MC, Nolkrantz K, O'Callaghan JP, Kennedy RT. Microscale sample deposition onto hydrophobic target plates for trace level detection of neuropeptides in brain tissue by MALDI-MS. Journal of Mass Spectrometry : Jms. 40: 1338-46. PMID 16217843 DOI: 10.1002/Jms.916  0.367
2005 Parkin MC, Wei H, O'Callaghan JP, Kennedy RT. Sample-dependent effects on the neuropeptidome detected in rat brain tissue preparations by capillary liquid chromatography with tandem mass spectrometry. Analytical Chemistry. 77: 6331-8. PMID 16194096 DOI: 10.1021/Ac050712D  0.337
2005 Dahlgren GM, Nolkrantz K, Kennedy RT. Effect of intracellular delivery of energy metabolites on intracellular Ca2+ in mouse islets of Langerhans. Life Sciences. 77: 2986-97. PMID 16002100 DOI: 10.1016/J.Lfs.2005.05.053  0.777
2005 Dahlgren GM, Kauri LM, Kennedy RT. Substrate effects on oscillations in metabolism, calcium and secretion in single mouse islets of Langerhans. Biochimica Et Biophysica Acta. 1724: 23-36. PMID 15882932 DOI: 10.1016/J.Bbagen.2005.04.007  0.776
2005 Gerin I, Dolinsky VW, Shackman JG, Kennedy RT, Chiang SH, Burant CF, Steffensen KR, Gustafsson JA, MacDougald OA. LXRbeta is required for adipocyte growth, glucose homeostasis, and beta cell function. The Journal of Biological Chemistry. 280: 23024-31. PMID 15831500 DOI: 10.1074/Jbc.M412564200  0.7
2005 Yang P, Whelan RJ, Jameson EE, Kurzer JH, Argetsinger LS, Carter-Su C, Kabir A, Malik A, Kennedy RT. Capillary electrophoresis and fluorescence anisotropy for quantitative analysis of peptide-protein interactions using JAK2 and SH2-Bβ as a model system Analytical Chemistry. 77: 2482-2489. PMID 15828784 DOI: 10.1021/Ac048307U  0.748
2005 Edwards JL, Kennedy RT. Metabolomic analysis of eukaryotic tissue and prokaryotes using negative mode MALDI time-of-flight mass spectrometry. Analytical Chemistry. 77: 2201-9. PMID 15801754 DOI: 10.1021/Ac048323R  0.593
2005 Rebec GV, Witowski SR, Sandstrom MI, Rostand RD, Kennedy RT. Extracellular ascorbate modulates cortically evoked glutamate dynamics in rat striatum. Neuroscience Letters. 378: 166-70. PMID 15781152 DOI: 10.1016/J.Neulet.2004.12.027  0.783
2005 Baseski HM, Watson CJ, Cellar NA, Shackman JG, Kennedy RT. Capillary liquid chromatography with MS3 for the determination of enkephalins in microdialysis samples from the striatum of anesthetized and freely-moving rats. Journal of Mass Spectrometry : Jms. 40: 146-53. PMID 15706617 DOI: 10.1002/Jms.733  0.803
2005 Shackman JG, Dahlgren GM, Peters JL, Kennedy RT. Perfusion and chemical monitoring of living cells on a microfluidic chip. Lab On a Chip. 5: 56-63. PMID 15616741 DOI: 10.1039/B404974H  0.805
2005 Jameson EE, Roof RA, Whorton MH, Mosberg HI, Sunahara RK, Neubig RR, Kennedy RT. Real-time detection of basal and stimulated G protein GTPase activity using fluorescent GTP analogues Journal of Biological Chemistry. 280: 7712-7719. PMID 15613467 DOI: 10.1074/Jbc.M413810200  0.691
2005 Park EJ, Reid KR, Tang W, Kennedy RT, Kopelman R. Erratum: Ratiometric fiber optic sensors for the detection of inter- and intra-cellular dissolved oxygen (Journal of Materials Chemistry (2005) 15 (2913)) Journal of Materials Chemistry. 15. DOI: 10.1039/B510210N  0.661
2005 Park EJ, Reid KR, Tang W, Kennedy RT, Kopelman R. Ratiometric fiber optic sensors for the detection of inter- and intra-cellular dissolved oxygen Journal of Materials Chemistry. 15: 2913-2919. DOI: 10.1039/B502981C  0.668
2004 Qian WJ, Peters JL, Dahlgren GM, Gee KR, Kennedy RT. Simultaneous monitoring of Zn2+ secretion and intracellular Ca2+ from islets and islet cells by fluorescence microscopy. Biotechniques. 37: 922-4, 926, 928-30 p. PMID 15597541 DOI: 10.2144/04376Bi01  0.791
2004 Whelan RJ, Sunahara RK, Neubig RR, Kennedy RT. Affinity assays using fluorescence anisotropy with capillary electrophoresis separation. Analytical Chemistry. 76: 7380-6. PMID 15595883 DOI: 10.1021/Ac0489566  0.344
2004 Haskins WE, Watson CJ, Cellar NA, Powell DH, Kennedy RT. Discovery and neurochemical screening of peptides in brain extracellular fluid by chemical analysis of in vivo microdialysis samples. Analytical Chemistry. 76: 5523-33. PMID 15362916 DOI: 10.1021/Ac049363Y  0.791
2004 Shou M, Smith AD, Shackman JG, Peris J, Kennedy RT. In vivo monitoring of amino acids by microdialysis sampling with on-line derivatization by naphthalene-2,3-dicarboxyaldehyde and rapid micellar electrokinetic capillary chromatography. Journal of Neuroscience Methods. 138: 189-97. PMID 15325127 DOI: 10.1016/J.Jneumeth.2004.04.006  0.789
2004 Cunliffe JM, Liu Z, Pawliszyn J, Kennedy RT. Use of a native affinity ligand for the detection of G proteins by capillary isoelectric focusing with laser-induced fluorescence detection. Electrophoresis. 25: 2319-25. PMID 15274014 DOI: 10.1002/Elps.200405953  0.748
2004 Smith A, Watson CJ, Frantz KJ, Eppler B, Kennedy RT, Peris J. Differential increase in taurine levels by low-dose ethanol in the dorsal and ventral striatum revealed by microdialysis with on-line capillary electrophoresis. Alcoholism, Clinical and Experimental Research. 28: 1028-38. PMID 15252289 DOI: 10.1097/01.Alc.0000131979.78003.34  0.487
2004 Rivera RM, Dahlgren GM, De Castro E Paula LA, Kennedy RT, Hansen PJ. Actions of thermal stress in two-cell bovine embryos: oxygen metabolism, glutathione and ATP content, and the time-course of development. Reproduction (Cambridge, England). 128: 33-42. PMID 15232062 DOI: 10.1530/Rep.1.00146  0.756
2004 Shackman JG, Watson CJ, Kennedy RT. High-throughput automated post-processing of separation data. Journal of Chromatography. A. 1040: 273-82. PMID 15230534 DOI: 10.1016/J.Chroma.2004.04.004  0.738
2004 Wei H, Nolkrantz K, Powell DH, Woods JH, Ko MC, Kennedy RT. Electrospray sample deposition for matrix-assisted laser desorption/ionization (MALDI) and atmospheric pressure MALDI mass spectrometry with attomole detection limits. Rapid Communications in Mass Spectrometry : Rcm. 18: 1193-200. PMID 15164348 DOI: 10.1002/Rcm.1458  0.342
2004 Kulkarni RN, Roper MG, Dahlgren G, Shih DQ, Kauri LM, Peters JL, Stoffel M, Kennedy RT. Islet secretory defect in insulin receptor substrate 1 null mice is linked with reduced calcium signaling and expression of sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA)-2b and -3. Diabetes. 53: 1517-25. PMID 15161756 DOI: 10.2337/Diabetes.53.6.1517  0.78
2004 Presti MF, Watson CJ, Kennedy RT, Yang M, Lewis MH. Behavior-related alterations of striatal neurochemistry in a mouse model of stereotyped movement disorder. Pharmacology, Biochemistry, and Behavior. 77: 501-7. PMID 15006460 DOI: 10.1016/J.Pbb.2003.12.004  0.505
2003 Roper MG, Shackman JG, Dahlgren GM, Kennedy RT. Microfluidic chip for continuous monitoring of hormone secretion from live cells using an electrophoresis-based immunoassay. Analytical Chemistry. 75: 4711-7. PMID 14674445 DOI: 10.1021/Ac0346813  0.794
2003 Jameson EE, Cunliffe JM, Neubig RR, Sunahara RK, Kennedy RT. Detection of G proteins by affinity probe capillary electrophoresis using a fluorescently labeled GTP analogue Analytical Chemistry. 75: 4297-4304. PMID 14632149 DOI: 10.1021/Ac0342976  0.797
2003 Qian WJ, Gee KR, Kennedy RT. Imaging of Zn2+ release from pancreatic beta-cells at the level of single exocytotic events. Analytical Chemistry. 75: 3468-75. PMID 14570199 DOI: 10.1021/Ac0341057  0.568
2003 Deng Q, Kauri LM, Qian WJ, Dahlgren GM, Kennedy RT. Microscale determination of purines in tissue samples by capillary liquid chromatography with electrochemical detection. The Analyst. 128: 1013-8. PMID 12964599 DOI: 10.1039/B303949H  0.805
2003 Deng Q, Watson CJ, Kennedy RT. Aptamer affinity chromatography for rapid assay of adenosine in microdialysis samples collected in vivo. Journal of Chromatography. A. 1005: 123-30. PMID 12924787 DOI: 10.1016/S0021-9673(03)00812-4  0.576
2003 Smith A, Watson CJ, Kennedy RT, Peris J. Ethanol-induced taurine efflux: low dose effects and high temporal resolution. Advances in Experimental Medicine and Biology. 526: 485-92. PMID 12908634  0.376
2003 Buchanan DD, Jameson EE, Perlette J, Malik A, Kennedy RT. Effect of buffer, electric field, and separation time on detection of aptamer-ligand complexes for affinity probe capillary electrophoresis. Electrophoresis. 24: 1375-82. PMID 12731022 DOI: 10.1002/Elps.200390176  0.787
2003 Kauri LM, Jung SK, Kennedy RT. Direct measurement of glucose gradients and mass transport within islets of Langerhans. Biochemical and Biophysical Research Communications. 304: 371-7. PMID 12711325 DOI: 10.1016/S0006-291X(03)00595-3  0.723
2002 Kennedy RT, Watson CJ, Haskins WE, Powell DH, Strecker RE. In vivo neurochemical monitoring by microdialysis and capillary separations. Current Opinion in Chemical Biology. 6: 659-65. PMID 12413551 DOI: 10.1016/S1367-5931(02)00373-3  0.748
2002 McKenzie JA, Watson CJ, Rostand RD, German I, Witowski SR, Kennedy RT. Automated capillary liquid chromatography for simultaneous determination of neuroactive amines and amino acids. Journal of Chromatography. A. 962: 105-15. PMID 12198955 DOI: 10.1016/S0021-9673(02)00533-2  0.8
2002 Kennedy RT, Thompson JE, Vickroy TW. In vivo monitoring of amino acids by direct sampling of brain extracellular fluid at ultralow flow rates and capillary electrophoresis. Journal of Neuroscience Methods. 114: 39-49. PMID 11850038 DOI: 10.1016/S0165-0270(01)00506-4  0.364
2002 Gee KR, Zhou ZL, Qian WJ, Kennedy R. Detection and imaging of zinc secretion from pancreatic beta-cells using a new fluorescent zinc indicator. Journal of the American Chemical Society. 124: 776-8. PMID 11817952 DOI: 10.1021/Ja011774Y  0.551
2002 Kennedy RT, Kauri LM, Dahlgren GM, Jung SK. Metabolic oscillations in beta-cells. Diabetes. 51: S152-61. PMID 11815475 DOI: 10.2337/Diabetes.51.2007.S152  0.777
2002 Roper MG, Qian WJ, Zhang BB, Kulkarni RN, Kahn CR, Kennedy RT. Effect of the insulin mimetic L-783,281 on intracellular Ca2+ and insulin secretion from pancreatic beta-cells. Diabetes. 51: S43-9. PMID 11815457 DOI: 10.2337/Diabetes.51.2007.S43  0.689
2002 Haskins WE, Watson CJ, Powell DH, Kennedy RT. Exploring the mammalian brain by in vivo microdialysis/capillary LC/MS 2 Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 49-50.  0.438
2002 Blagojevic T, Haskins WE, Watson CJ, Powell DH, Kennedy RT. Capillary LC/MALDI-TOF MS for identification of endogenous neuropeptides Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 375-376.  0.443
2001 Deng Q, German I, Buchanan D, Kennedy RT. Retention and separation of adenosine and analogues by affinity chromatography with an aptamer stationary phase. Analytical Chemistry. 73: 5415-21. PMID 11816567 DOI: 10.1021/Ac0105437  0.783
2001 Haskins WE, Wang Z, Watson CJ, Rostand RR, Witowski SR, Powell DH, Kennedy RT. Capillary LC-MS2 at the attomole level for monitoring and discovering endogenous peptides in microdialysis samples collected in vivo. Analytical Chemistry. 73: 5005-14. PMID 11721892 DOI: 10.1021/Ac010774D  0.801
2001 Bowser MT, Kennedy RT. In vivo monitoring of amine neurotransmitters using microdialysis with on-line capillary electrophoresis. Electrophoresis. 22: 3668-76. PMID 11699904 DOI: 10.1002/1522-2683(200109)22:17<3668::Aid-Elps3668>3.0.Co;2-M  0.681
2001 German I, Roper MG, Kalra SP, Rhinehart E, Kennedy RT. Capillary liquid chromatography of multiple peptides with on-line capillary electrophoresis immunoassay detection. Electrophoresis. 22: 3659-67. PMID 11699903 DOI: 10.1002/1522-2683(200109)22:17<3659::Aid-Elps3659>3.0.Co;2-I  0.814
2001 Boyd BW, Kennedy RT. Automated capillary liquid chromatography for high sensitivity amino acid monitoring Journal of Microcolumn Separations. 13: 24-32. DOI: 10.1002/Mcs.1015  0.368
2000 Paras CD, Qian W, Lakey JR, Tan W, Kennedy RT. Localized exocytosis detected by spatially resolved amperometry in single pancreatic beta-cells. Cell Biochemistry and Biophysics. 33: 227-40. PMID 11325043 DOI: 10.1385/Cbb:33:3:227  0.533
2000 German I, Kennedy RT. Reversed-phase capillary liquid chromatography coupled on-line to capillary electrophoresis immunoassays. Analytical Chemistry. 72: 5365-72. PMID 11080889 DOI: 10.1021/Ac000549G  0.815
2000 German I, Kennedy RT. Rapid simultaneous determination of glucagon and insulin by capillary electrophoresis immunoassays. Journal of Chromatography. B, Biomedical Sciences and Applications. 742: 353-62. PMID 10901140 DOI: 10.1016/S0378-4347(00)00180-8  0.809
2000 Aspinwall CA, Qian WJ, Roper MG, Kulkarni RN, Kahn CR, Kennedy RT. Roles of insulin receptor substrate-1, phosphatidylinositol 3-kinase, and release of intracellular Ca2+ stores in insulin-stimulated insulin secretion in beta -cells. The Journal of Biological Chemistry. 275: 22331-8. PMID 10764813 DOI: 10.1074/Jbc.M909647199  0.745
2000 Boyd BW, Witowski SR, Kennedy RT. Trace-level amino acid analysis by capillary liquid chromatography and application to in vivo microdialysis sampling with 10-s temporal resolution. Analytical Chemistry. 72: 865-71. PMID 10701275 DOI: 10.1021/Ac990872N  0.811
2000 Qian WJ, Aspinwall CA, Battiste MA, Kennedy RT. Detection of secretion from single pancreatic beta-cells using extracellular fluorogenic reactions and confocal fluorescence microscopy. Analytical Chemistry. 72: 711-7. PMID 10701254 DOI: 10.1021/Ac991085T  0.655
2000 Jung SK, Kauri LM, Qian WJ, Kennedy RT. Correlated oscillations in glucose consumption, oxygen consumption, and intracellular free Ca(2+) in single islets of Langerhans. The Journal of Biological Chemistry. 275: 6642-50. PMID 10692473 DOI: 10.1074/Jbc.275.9.6642  0.723
2000 Jhaveri SD, Kirby R, Conrad R, Maglott EJ, Bowser M, Kennedy RT, Glick G, Ellington AD. Designed signaling aptamers that transduce molecular recognition to changes in fluorescence intensity Journal of the American Chemical Society. 122: 2469-2473. DOI: 10.1021/Ja992393B  0.618
1999 Kennedy RT, German I, Thompson JE, Witowski SR. Fast analytical-scale separations by capillary electrophoresis and liquid chromatography. Chemical Reviews. 99: 3081-132. PMID 11749511 DOI: 10.1021/Cr980134J  0.791
1999 Battersby TR, Ang DN, Burgstaller P, Jurczyk SC, Bowser MT, Buchanan DD, Kennedy RT, Benner SA. Quantitative analysis of receptors for adenosine nucleotides obtained via in vitro selection from a library incorporating a cationic nucleotide analog. Journal of the American Chemical Society. 121: 9781-9. PMID 11543572 DOI: 10.1021/Ja9816436  0.766
1999 Lakey JR, Aspinwall CA, Cavanagh TJ, Kennedy RT. Secretion from islets and single islet cells following cryopreservation. Cell Transplantation. 8: 691-8. PMID 10701497 DOI: 10.1177/096368979900800614  0.645
1999 Aspinwall CA, Huang L, Lakey JR, Kennedy RT. Comparison of amperometric methods for detection of exocytosis from single pancreatic beta-cells of different species. Analytical Chemistry. 71: 5551-6. PMID 10624159 DOI: 10.1021/Ac990817E  0.636
1999 Heegaard NH, Kennedy RT. Identification, quantitation, and characterization of biomolecules by capillary electrophoretic analysis of binding interactions. Electrophoresis. 20: 3122-33. PMID 10596820 DOI: 10.1002/(Sici)1522-2683(19991001)20:15/16<3122::Aid-Elps3122>3.0.Co;2-M  0.338
1999 Jung SK, Gorski W, Aspinwall CA, Kauri LM, Kennedy RT. Oxygen microsensor and its application to single cells and mouse pancreatic islets. Analytical Chemistry. 71: 3642-9. PMID 10489519 DOI: 10.1021/Ac990271W  0.78
1999 Thompson JE, Vickroy TW, Kennedy RT. Rapid determination of aspartate enantiomers in tissue samples by microdialysis coupled on-line with capillary electrophoresis. Analytical Chemistry. 71: 2379-84. PMID 10405606 DOI: 10.1021/Ac981115C  0.342
1999 Jung SK, Aspinwall CA, Kennedy RT. Detection of multiple patterns of oscillatory oxygen consumption in single mouse islets of Langerhans. Biochemical and Biophysical Research Communications. 259: 331-5. PMID 10362508 DOI: 10.1006/Bbrc.1999.0784  0.63
1999 Shen H, Witowski SR, Boyd BW, Kennedy RT. Detection of peptides by precolumn derivatization with biuret reagent and preconcentration on capillary liquid chromatography columns with electrochemical detection. Analytical Chemistry. 71: 987-94. PMID 10079760 DOI: 10.1021/Ac9809837  0.803
1999 Aspinwall CA, Lakey JR, Kennedy RT. Insulin-stimulated insulin secretion in single pancreatic beta cells. The Journal of Biological Chemistry. 274: 6360-5. PMID 10037726 DOI: 10.1074/Jbc.274.10.6360  0.636
1999 Kennedy RT. Bioanalytical applications of fast capillary electrophoresis Analytica Chimica Acta. 400: 163-180. DOI: 10.1016/S0003-2670(99)00657-1  0.352
1999 Witowski SR, Kennedy RT. Pressure- and electroosmotically-driven flow in capillaries packed with nonporous particles for high-Speed separations Journal of Microcolumn Separations. 11: 723-728. DOI: 10.1002/(Sici)1520-667X(1999)11:10<723::Aid-Mcs5>3.0.Co;2-N  0.779
1998 Tao L, Thompson JE, Kennedy RT. Optically Gated Capillary Electrophoresis of o-Phthalaldehyde/β-Mercaptoethanol Derivatives of Amino Acids for Chemical Monitoring. Analytical Chemistry. 70: 4015-22. PMID 21651238 DOI: 10.1021/Ac980324U  0.349
1998 Boyd BW, Kennedy RT. Determination of trace level gamma-aminobutyric acid using an improved OPA pre-column derivatization and on-column preconcentration capillary liquid chromatography with electrochemical detection. The Analyst. 123: 2119-24. PMID 10209896 DOI: 10.1039/A804442B  0.356
1998 German I, Buchanan DD, Kennedy RT. Aptamers as ligands in affinity probe capillary electrophoresis. Analytical Chemistry. 70: 4540-5. PMID 9823713 DOI: 10.1021/Ac980638H  0.788
1998 Tao L, Aspinwall CA, Kennedy RT. On-line competitive immunoassay based on capillary electrophoresis applied to monitoring insulin secretion from single islets of Langerhans. Electrophoresis. 19: 403-8. PMID 9551792 DOI: 10.1002/Elps.1150190307  0.643
1998 Lakey JR, Aspinwall CA, Cavanagh TJ, Kennedy RT. Effect of cryopreservation on canine islet insulin secretion as measured by amperometric techniques. Transplantation Proceedings. 30: 382. PMID 9532091 DOI: 10.1016/S0041-1345(97)01319-5  0.622
1998 Lada MW, Vickroy TW, Kennedy RT. Evidence for neuronal origin and metabotropic receptor-mediated regulation of extracellular glutamate and aspartate in rat striatum in vivo following electrical stimulation of the prefrontal cortex. Journal of Neurochemistry. 70: 617-25. PMID 9453555 DOI: 10.1046/J.1471-4159.1998.70020617.X  0.31
1998 Tao L, Kennedy RT. Laser-induced fluorescence detection in microcolumn separations Trac - Trends in Analytical Chemistry. 17: 484-491. DOI: 10.1016/S0165-9936(98)00056-9  0.319
1997 Shen H, Lada MW, Kennedy RT. Monitoring of met-enkephalin in vivo with 5-min temporal resolution using microdialysis sampling and capillary liquid chromatography with electrochemical detection. Journal of Chromatography. B, Biomedical Sciences and Applications. 704: 43-52. PMID 9518176 DOI: 10.1016/S0378-4347(97)00436-2  0.404
1997 Aspinwall CA, Brooks SA, Kennedy RT, Lakey JR. Effects of intravesicular H+ and extracellular H+ and Zn2+ on insulin secretion in pancreatic beta cells. The Journal of Biological Chemistry. 272: 31308-14. PMID 9395458 DOI: 10.1074/Jbc.272.50.31308  0.639
1997 Lada MW, Vickroy TW, Kennedy RT. High temporal resolution monitoring of glutamate and aspartate in vivo using microdialysis on-line with capillary electrophoresis with laser-induced fluorescence detection. Analytical Chemistry. 69: 4560-5. PMID 9375517 DOI: 10.1021/Ac970518U  0.362
1997 Zhang Q, Tally M, Larsson O, Kennedy RT, Huang L, Hall K, Berggren PO. Insulin-like growth factor II signaling through the insulin-like growth factor II/mannose-6-phosphate receptor promotes exocytosis in insulin-secreting cells. Proceedings of the National Academy of Sciences of the United States of America. 94: 6232-7. PMID 9177200 DOI: 10.1073/Pnas.94.12.6232  0.658
1997 Lada MW, Kennedy RT. In vivo monitoring of glutathione and cysteine in rat caudate nucleus using microdialysis on-line with capillary zone electrophoresis-laser induced fluorescence detection. Journal of Neuroscience Methods. 72: 153-9. PMID 9133579 DOI: 10.1016/S0165-0270(96)02174-7  0.386
1997 Shen H, Aspinwall CA, Kennedy RT. Dual microcolumn immunoassay applied to determination of insulin secretion from single islets of Langerhans and insulin in serum. Journal of Chromatography. B, Biomedical Sciences and Applications. 689: 295-303. PMID 9080314 DOI: 10.1016/S0378-4347(96)00336-2  0.666
1997 Tao L, Kennedy RT. Measurement of antibody-antigen dissociation constants using fast capillary electrophoresis with laser-induced fluorescence detection. Electrophoresis. 18: 112-7. PMID 9059831 DOI: 10.1002/Elps.1150180121  0.318
1997 Gorski W, Aspinwall CA, Lakey JR, Kennedy RT. Ruthenium catalyst for amperometric determination of insulin at physiological pH Journal of Electroanalytical Chemistry. 425: 191-199. DOI: 10.1016/S0022-0728(96)04936-4  0.645
1996 Tao L, Kennedy RT. On-line competitive immunoassay for insulin based on capillary electrophoresis with laser-induced fluorescence detection. Analytical Chemistry. 68: 3899-906. PMID 8916449 DOI: 10.1021/Ac960560+  0.354
1996 Lada MW, Kennedy RT. Quantitative in vivo monitoring of primary amines in rat caudate nucleus using microdialysis coupled by a flow-gated interface to capillary electrophoresis with laser-induced fluorescence detection. Analytical Chemistry. 68: 2790-7. PMID 8794915 DOI: 10.1021/Ac960178X  0.404
1996 Finnegan JM, Pihel K, Cahill PS, Huang L, Zerby SE, Ewing AG, Kennedy RT, Wightman RM. Vesicular quantal size measured by amperometry at chromaffin, mast, pheochromocytoma, and pancreatic beta-cells. Journal of Neurochemistry. 66: 1914-23. PMID 8780018 DOI: 10.1046/J.1471-4159.1996.66051914.X  0.661
1996 Kennedy RT, Huang L, Aspinwall CA. Extracellular pH Is Required for Rapid Release of Insulin from Zn−Insulin Precipitates in β-Cell Secretory Vesicles during Exocytosis Journal of the American Chemical Society. 118: 1795-1796. DOI: 10.1021/Ja953271W  0.622
1995 Lada MW, Kennedy RT. Quantitative in vivo measurements using microdialysis on-line with capillary zone electrophoresis. Journal of Neuroscience Methods. 63: 147-52. PMID 8788059 DOI: 10.1016/0165-0270(95)00104-2  0.35
1995 Paras CD, Kennedy RT. Electrochemical detection of exocytosis at single rat melanotrophs. Analytical Chemistry. 67: 3633-7. PMID 8644916 DOI: 10.1021/Ac00116A003  0.315
1995 Schultz NM, Huang L, Kennedy RT. Capillary electrophoresis-based immunoassay to determine insulin content and insulin secretion from single islets of Langerhans. Analytical Chemistry. 67: 924-9. PMID 7762828 DOI: 10.1021/Ac00101A020  0.344
1995 Cole LJ, Kennedy RT. Selective preconcentration for capillary zone electrophoresis using protein G immunoaffinity capillary chromatography. Electrophoresis. 16: 549-56. PMID 7588525 DOI: 10.1002/Elps.1150160190  0.368
1995 Huang L, Shen H, Atkinson MA, Kennedy RT. Detection of exocytosis at individual pancreatic beta cells by amperometry at a chemically modified microelectrode. Proceedings of the National Academy of Sciences of the United States of America. 92: 9608-12. PMID 7568182 DOI: 10.1073/Pnas.92.21.9608  0.343
1995 Huang L, Kennedy RT. Exploring single-cell dynamics using chemically-modified microelectrodes Trends in Analytical Chemistry. 14: 158-164. DOI: 10.1016/0165-9936(95)98313-W  0.337
1995 Lada MW, Schaller G, Carriger MH, Vickroy TW, Kennedy RT. On-line interface between microdialysis and capillary zone electrophoresis Analytica Chimica Acta. 307: 217-225. DOI: 10.1016/0003-2670(94)00505-G  0.372
1993 Kennedy RT, Huang L, Atkinson MA, Dush P. Amperometric monitoring of chemical secretions from individual pancreatic beta-cells. Analytical Chemistry. 65: 1882-7. PMID 8368536 DOI: 10.1021/Ac00062A012  0.327
1993 Schultz NM, Kennedy RT. Rapid immunoassays using capillary electrophoresis with fluorescence detection Analytical Chemistry. 65: 3161-3165. DOI: 10.1021/Ac00069A035  0.307
1993 Cole LJ, Schultz NM, Kennedy RT. Effect of column diameter on plate height in high speed liquid chromatography using pellicular and perfused particles in packed capillaries Journal of Microcolumn Separations. 5: 433-439. DOI: 10.1002/Mcs.1220050507  0.307
1992 Zimmerman JB, Kennedy RT, Wightman RM. Evoked neuronal activity accompanied by transmitter release increases oxygen concentration in rat striatum in vivo but not in vitro. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 12: 629-37. PMID 1618942 DOI: 10.1038/Jcbfm.1992.87  0.593
1992 Kennedy RT, Jones SR, Wightman RM. Dynamic observation of dopamine autoreceptor effects in rat striatal slices. Journal of Neurochemistry. 59: 449-55. PMID 1352798 DOI: 10.1111/J.1471-4159.1992.Tb09391.X  0.65
1992 Kennedy RT, Jones SR, Wightman RM. Simultaneous measurement of oxygen and dopamine: coupling of oxygen consumption and neurotransmission. Neuroscience. 47: 603-12. PMID 1316568 DOI: 10.1016/0306-4522(92)90169-3  0.657
1991 Wightman RM, Jankowski JA, Kennedy RT, Kawagoe KT, Schroeder TJ, Leszczyszyn DJ, Near JA, Diliberto EJ, Viveros OH. Temporally resolved catecholamine spikes correspond to single vesicle release from individual chromaffin cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 10754-8. PMID 1961743 DOI: 10.1073/Pnas.88.23.10754  0.692
1991 Wiedemann DJ, Kawagoe KT, Kennedy RT, Ciolkowski EL, Wightman RM. Strategies for low detection limit measurements with cyclic voltammetry. Analytical Chemistry. 63: 2965-70. PMID 1789456 DOI: 10.1021/Ac00024A030  0.666
1990 Kennedy RT, Jorgenson JW. Efficiency of packed microcolumns compared with large-bore packed columns in size-exclusion chromatography Journal of Microcolumn Separations. 2: 120-126. DOI: 10.1002/Mcs.1220020307  0.678
1989 Kennedy RT, Jorgenson JW. Quantitative analysis of individual neurons by open tubular liquid chromatography with voltammetric detection. Analytical Chemistry. 61: 436-41. PMID 2719258 DOI: 10.1021/Ac00180A012  0.689
1989 Kennedy RT, Oates MD, Cooper BR, Nickerson B, Jorgenson JW. Microcolumn separations and the analysis of single cells. Science (New York, N.Y.). 246: 57-63. PMID 2675314 DOI: 10.1126/Science.2675314  0.698
1989 Geng L, Reed RA, Kim MH, Wooster TT, Oliver BN, Egekeze J, Kennedy RT, Jorgenson JW, Parcher JF, Murray RW. Chemical phenomena in solid-state voltammetry in polymer solvents Journal of the American Chemical Society. 111: 1614-1619. DOI: 10.1021/Ja00187A013  0.668
1989 Moseley MA, Deterding LJ, De Wit JSM, Tomer KB, Kennedy RT, Bragg N, Jorgenson JW. Optimization of a coaxial continuous flow fast atom bombardment interface between capillary liquid chromatography and magnetic sector mass spectrometry for the analysis of biomolecules Analytical Chemistry. 61: 1577-1584. DOI: 10.1021/Ac00189A021  0.665
1989 Kennedy RT, Jorgenson JW. Preparation and evaluation of packed capillary liquid chromatography columns with inner diameters from 20 to 50 micrometers Analytical Chemistry. 61: 1128-1135. DOI: 10.1021/Ac00185A016  0.644
1988 Jorgenson J, Kennedy R, St. Claire, III R, White J, Dluzneski P, de Wit J. Open tubular liquid-chromatography and the analysis of single neurons Journal of Research of the National Bureau of Standards. 93: 403. DOI: 10.6028/Jres.093.094  0.679
1988 Kennedy RT, Jorgenson JW. Pneumatic microsyringe for use as an injector in open tubular liquid chromatography and as a dispenser in microanalysis Analytical Chemistry. 60: 1521-1524. DOI: 10.1021/Ac00166A009  0.66
1987 Kennedy RT, St. Claire RL, White JG, Jorgenson JW. Chemical analysis of single neurons by open tubular liquid chromatography Mikrochimica Acta. 92: 37-45. DOI: 10.1007/Bf01201715  0.679
Show low-probability matches.