James Riley Broach - Publications

Affiliations: 
1984-2012 Molecular Biology Princeton University, Princeton, NJ 
 2012- Penn State Hershey College of Medicine 
Area:
signaling pathways
Website:
https://molbio.princeton.edu/people/james-r-broach

119 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Zhang J, Lee D, Dhiman V, Jiang P, Xu J, McGillivray P, Yang H, Liu J, Meyerson W, Clarke D, Gu M, Li S, Lou S, Xu J, Lochovsky L, ... ... Broach JR, et al. An integrative ENCODE resource for cancer genomics. Nature Communications. 11: 3696. PMID 32728046 DOI: 10.1038/S41467-020-14743-W  0.335
2018 Conlon EG, Fagegaltier D, Agius P, Davis-Porada J, Gregory J, Hubbard I, Kang K, Kim D, Phatnani H, Kwan J, Sareen D, Broach JR, Simmons Z, Arcila-Londono X, Lee EB, et al. Author response: Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism Elife. DOI: 10.7554/Elife.37754.025  0.447
2017 Kurischko C, Broach JR. Phosphorylation and nuclear transit modulate the balance between normal function and terminal aggregation of the yeast RNA-binding protein Ssd1. Molecular Biology of the Cell. PMID 28877986 DOI: 10.1091/Mbc.E17-02-0100  0.31
2017 Coble JL, Sheldon K, Yue F, Salameh T, Harris L, Deiling S, Ruggiero F, Eshelman M, Yochum GS, Koltun WA, Gerhard GS, Broach JR. Identification of a rare LAMB4 variant associated with familial diverticulitis through exome sequencing. Human Molecular Genetics. PMID 28595269 DOI: 10.1093/Hmg/Ddx204  0.301
2017 Chereji RV, Bharatula V, Elfving N, Blomberg J, Larsson M, Morozov AV, Broach JR, Björklund S. Mediator binds to boundaries of chromosomal interaction domains and to proteins involved in DNA looping, RNA metabolism, chromatin remodeling, and actin assembly. Nucleic Acids Research. PMID 28575439 DOI: 10.1093/Nar/Gkx491  0.343
2014 Elfving N, Chereji RV, Bharatula V, Björklund S, Morozov AV, Broach JR. A dynamic interplay of nucleosome and Msn2 binding regulates kinetics of gene activation and repression following stress. Nucleic Acids Research. 42: 5468-82. PMID 24598258 DOI: 10.1093/Nar/Gku176  0.336
2014 Nati T, Bravim F, Soares J, Mota MM, Broach JR, Fernandes AAR, Fernandes PMB. Monitoring expression of yeast cell wall protein-encoding genes in response to high hydrostatic pressure Bmc Proceedings. 8. DOI: 10.1186/1753-6561-8-S4-P205  0.35
2014 Soares J, Bravim F, Nati T, Mota MM, Broach JR, Ribeiro Fernandes AA, Bueno Fernandes PM. Effect of high hydrostatic pressure on the biosynthesis of sulfur amino acids in Saccharomyces cerevisiae Bmc Proceedings. 8. DOI: 10.1186/1753-6561-8-S4-P135  0.333
2013 Petrenko N, Chereji RV, McClean MN, Morozov AV, Broach JR. Noise and interlocking signaling pathways promote distinct transcription factor dynamics in response to different stresses. Molecular Biology of the Cell. 24: 2045-57. PMID 23615444 DOI: 10.1091/Mbc.E12-12-0870  0.329
2013 Bravim F, Lippman SI, da Silva LF, Souza DT, Fernandes AA, Masuda CA, Broach JR, Fernandes PM. High hydrostatic pressure activates gene expression that leads to ethanol production enhancement in a Saccharomyces cerevisiae distillery strain. Applied Microbiology and Biotechnology. 97: 2093-107. PMID 22915193 DOI: 10.1007/S00253-012-4356-X  0.32
2012 Bravim F, da Silva LF, Souza DT, Lippman SI, Broach JR, Fernandes AA, Fernandes PM. High hydrostatic pressure activates transcription factors involved in Saccharomyces cerevisiae stress tolerance. Current Pharmaceutical Biotechnology. 13: 2712-20. PMID 23072392 DOI: 10.2174/138920112804724891  0.319
2012 Broach JR. Nutritional control of growth and development in yeast. Genetics. 192: 73-105. PMID 22964838 DOI: 10.1534/Genetics.111.135731  0.329
2012 Xu YF, Zhao X, Glass DS, Absalan F, Perlman DH, Broach JR, Rabinowitz JD. Regulation of yeast pyruvate kinase by ultrasensitive allostery independent of phosphorylation. Molecular Cell. 48: 52-62. PMID 22902555 DOI: 10.1016/J.Molcel.2012.07.013  0.308
2011 Tsitron J, Ault AD, Broach JR, Morozov AV. Decoding complex chemical mixtures with a physical model of a sensor array. Plos Computational Biology. 7: e1002224. PMID 22046111 DOI: 10.1371/Journal.Pcbi.1002224  0.648
2011 Tolkunov D, Zawadzki KA, Singer C, Elfving N, Morozov AV, Broach JR. Chromatin remodelers clear nucleosomes from intrinsically unfavorable sites to establish nucleosome-depleted regions at promoters. Molecular Biology of the Cell. 22: 2106-18. PMID 21508315 DOI: 10.1091/Mbc.E10-10-0826  0.339
2011 Klosinska MM, Crutchfield CA, Bradley PH, Rabinowitz JD, Broach JR. Yeast cells can access distinct quiescent states. Genes & Development. 25: 336-49. PMID 21289062 DOI: 10.1101/Gad.2011311  0.744
2010 Talarek N, Cameroni E, Jaquenoud M, Luo X, Bontron S, Lippman S, Devgan G, Snyder M, Broach JR, De Virgilio C. Initiation of the TORC1-regulated G0 program requires Igo1/2, which license specific mRNAs to evade degradation via the 5'-3' mRNA decay pathway. Molecular Cell. 38: 345-55. PMID 20471941 DOI: 10.1016/J.Molcel.2010.02.039  0.317
2009 Shor E, Warren CL, Tietjen J, Hou Z, Müller U, Alborelli I, Gohard FH, Yemm AI, Borisov L, Broach JR, Weinreich M, Nieduszynski CA, Ansari AZ, Fox CA. The origin recognition complex interacts with a subset of metabolic genes tightly linked to origins of replication Plos Genetics. 5. PMID 19997491 DOI: 10.1371/Journal.Pgen.1000755  0.375
2009 Lippman SI, Broach JR. Protein kinase A and TORC1 activate genes for ribosomal biogenesis by inactivating repressors encoded by Dot6 and its homolog Tod6. Proceedings of the National Academy of Sciences of the United States of America. 106: 19928-33. PMID 19901341 DOI: 10.1073/Pnas.0907027106  0.387
2009 Zawadzki KA, Morozov AV, Broach JR. Chromatin-dependent transcription factor accessibility rather than nucleosome remodeling predominates during global transcriptional restructuring in Saccharomyces cerevisiae. Molecular Biology of the Cell. 20: 3503-13. PMID 19494041 DOI: 10.1091/Mbc.E09-02-0111  0.327
2009 Evans BJ, Wang Z, Broach JR, Oishi S, Fujii N, Peiper SC. Expression of CXCR4, a G-protein-coupled receptor for CXCL12 in yeast identification of new-generation inverse agonists. Methods in Enzymology. 460: 399-412. PMID 19446737 DOI: 10.1016/S0076-6879(09)05220-3  0.337
2009 Freckleton G, Lippman SI, Broach JR, Tavazoie S. Microarray profiling of phage-display selections for rapid mapping of transcription factor-DNA interactions. Plos Genetics. 5: e1000449. PMID 19360118 DOI: 10.1371/Journal.Pgen.1000449  0.313
2009 Zaman S, Lippman SI, Schneper L, Slonim N, Broach JR. Glucose regulates transcription in yeast through a network of signaling pathways. Molecular Systems Biology. 5: 245. PMID 19225458 DOI: 10.1038/Msb.2009.2  0.318
2009 Airoldi EM, Huttenhower C, Gresham D, Lu C, Caudy AA, Dunham MJ, Broach JR, Botstein D, Troyanskaya OG. Predicting cellular growth from gene expression signatures. Plos Computational Biology. 5: e1000257. PMID 19119411 DOI: 10.1371/Journal.Pcbi.1000257  0.343
2008 Tan MP, Smith EN, Broach JR, Floudas CA. Microarray data mining: a novel optimization-based approach to uncover biologically coherent structures. Bmc Bioinformatics. 9: 268. PMID 18538024 DOI: 10.1186/1471-2105-9-268  0.63
2007 Tan MP, Broach JR, Floudas CA. Evaluation of normalization and pre-clustering issues in a novel clustering approach: global optimum search with enhanced positioning. Journal of Bioinformatics and Computational Biology. 5: 895-913. PMID 17787062 DOI: 10.1142/S0219720007002941  0.618
2007 Yorimitsu T, Zaman S, Broach JR, Klionsky DJ. Protein kinase A and Sch9 cooperatively regulate induction of autophagy in Saccharomyces cerevisiae. Molecular Biology of the Cell. 18: 4180-9. PMID 17699586 DOI: 10.1091/Mbc.E07-05-0485  0.303
2007 Urban J, Soulard A, Huber A, Lippman S, Mukhopadhyay D, Deloche O, Wanke V, Anrather D, Ammerer G, Riezman H, Broach JR, De Virgilio C, Hall MN, Loewith R. Sch9 is a major target of TORC1 in Saccharomyces cerevisiae. Molecular Cell. 26: 663-74. PMID 17560372 DOI: 10.1016/J.Molcel.2007.04.020  0.324
2007 McClean MN, Mody A, Broach JR, Ramanathan S. Cross-talk and decision making in MAP kinase pathways. Nature Genetics. 39: 409-14. PMID 17259986 DOI: 10.1038/Ng1957  0.319
2007 Tan MP, Broach JR, Floudas CA. A novel clustering approach and prediction of optimal number of clusters: Global optimum search with enhanced positioning Journal of Global Optimization. 39: 323-346. DOI: 10.1007/S10898-007-9140-6  0.616
2006 Wang ZX, Broach JR, Peiper SC. Functional expression of CXCR4 in Saccharomyces cerevisiae in the development of powerful tools for the pharmacological characterization of CXCR4. Methods in Molecular Biology (Clifton, N.J.). 332: 115-27. PMID 16878688 DOI: 10.1385/1-59745-048-0:115  0.351
2006 Xu EY, Zawadzki KA, Broach JR. Single-cell observations reveal intermediate transcriptional silencing states. Molecular Cell. 23: 219-29. PMID 16857588 DOI: 10.1016/J.Molcel.2006.05.035  0.362
2006 Houston PL, Broach JR. The dynamics of homologous pairing during mating type interconversion in budding yeast. Plos Genetics. 2: e98. PMID 16789829 DOI: 10.1371/Journal.Pgen.0020098  0.376
2006 Ault AD, Broach JR. Creation of GPCR-based chemical sensors by directed evolution in yeast. Protein Engineering, Design & Selection : Peds. 19: 1-8. PMID 16263727 DOI: 10.1093/Protein/Gzi069  0.66
2006 Niida A, Wang Z, Tomita K, Oishi S, Tamamura H, Otaka A, Navenot JM, Broach JR, Peiper SC, Fujii N. Design and synthesis of downsized metastin (45-54) analogs with maintenance of high GPR54 agonistic activity. Bioorganic & Medicinal Chemistry Letters. 16: 134-7. PMID 16242330 DOI: 10.1016/J.Bmcl.2005.09.054  0.339
2005 Xu EY, Bi X, Holland MJ, Gottschling DE, Broach JR. Mutations in the nucleosome core enhance transcriptional silencing. Molecular and Cellular Biology. 25: 1846-59. PMID 15713639 DOI: 10.1128/Mcb.25.5.1846-1859.2005  0.317
2004 Schneper L, Düvel K, Broach JR. Sense and sensibility: nutritional response and signal integration in yeast. Current Opinion in Microbiology. 7: 624-30. PMID 15556035 DOI: 10.1016/J.Mib.2004.10.002  0.348
2004 Santhanam A, Hartley A, Düvel K, Broach JR, Garrett S. PP2A phosphatase activity is required for stress and Tor kinase regulation of yeast stress response factor Msn2p. Eukaryotic Cell. 3: 1261-71. PMID 15470255 DOI: 10.1128/Ec.3.5.1261-1271.2004  0.36
2004 Jorgensen P, Rupes I, Sharom JR, Schneper L, Broach JR, Tyers M. A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size. Genes & Development. 18: 2491-505. PMID 15466158 DOI: 10.1101/Gad.1228804  0.365
2004 Wang Y, Pierce M, Schneper L, Güldal CG, Zhang X, Tavazoie S, Broach JR. Ras and Gpa2 mediate one branch of a redundant glucose signaling pathway in yeast. Plos Biology. 2: E128. PMID 15138498 DOI: 10.1371/Journal.Pbio.0020128  0.361
2004 Houston P, Simon PJ, Broach JR. The Saccharomyces cerevisiae recombination enhancer biases recombination during interchromosomal mating-type switching but not in interchromosomal homologous recombination. Genetics. 166: 1187-97. PMID 15082540 DOI: 10.1534/Genetics.166.3.1187  0.313
2004 Schneper L, Krauss A, Miyamoto R, Fang S, Broach JR. The Ras/protein kinase A pathway acts in parallel with the Mob2/Cbk1 pathway to effect cell cycle progression and proper bud site selection. Eukaryotic Cell. 3: 108-20. PMID 14871942 DOI: 10.1128/Ec.3.1.108-120.2004  0.4
2003 Lin X, Floudas CA, Wang Y, Broach JR. Theoretical and computational studies of the glucose signaling pathways in yeast using global gene expression data. Biotechnology and Bioengineering. 84: 864-86. PMID 14708127 DOI: 10.1002/Bit.10844  0.509
2003 Düvel K, Broach JR. The role of phosphatases in TOR signaling in yeast. Current Topics in Microbiology and Immunology. 279: 19-38. PMID 14560949 DOI: 10.1007/978-3-642-18930-2_2  0.373
2003 Alvarez Arias D, Navenot JM, Zhang WB, Broach J, Peiper SC. Constitutive activation of CCR5 and CCR2 induced by conformational changes in the conserved TXP motif in transmembrane helix 2. The Journal of Biological Chemistry. 278: 36513-21. PMID 12837756 DOI: 10.1074/Jbc.M303739200  0.315
2003 Düvel K, Santhanam A, Garrett S, Schneper L, Broach JR. Multiple roles of Tap42 in mediating rapamycin-induced transcriptional changes in yeast. Molecular Cell. 11: 1467-78. PMID 12820961 DOI: 10.1016/S1097-2765(03)00228-4  0.404
2003 Yu Q, Qiu R, Foland TB, Griesen D, Galloway CS, Chiu YH, Sandmeier J, Broach JR, Bi X. Rap1p and other transcriptional regulators can function in defining distinct domains of gene expression. Nucleic Acids Research. 31: 1224-33. PMID 12582242 DOI: 10.1093/Nar/Gkg200  0.348
2002 Simon P, Houston P, Broach J. Directional bias during mating type switching in Saccharomyces is independent of chromosomal architecture Embo Journal. 21: 2282-2291. PMID 11980725 DOI: 10.1093/Emboj/21.9.2282  0.301
2002 Zhang WB, Navenot JM, Haribabu B, Tamamura H, Hiramatu K, Omagari A, Pei G, Manfredi JP, Fujii N, Broach JR, Peiper SC. A point mutation that confers constitutive activity to CXCR4 reveals that T140 is an inverse agonist and that AMD3100 and ALX40-4C are weak partial agonists. The Journal of Biological Chemistry. 277: 24515-21. PMID 11923301 DOI: 10.1074/Jbc.M200889200  0.325
2001 Nielsen KH, Gredsted L, Broach JR, Willumsen BM. Sensitivity of wild type and mutant ras alleles to Ras specific exchange factors: Identification of factor specific requirements. Oncogene. 20: 2091-100. PMID 11360193 DOI: 10.1038/Sj.Onc.1204306  0.33
2001 Bi X, Broach JR. Chromosomal boundaries in S. cerevisiae Current Opinion in Genetics and Development. 11: 199-204. PMID 11250144 DOI: 10.1016/S0959-437X(00)00179-9  0.343
2001 Johnston SD, Enomoto S, Schneper L, McClellan MC, Twu F, Montgomery ND, Haney SA, Broach JR, Berman J. CAC3(MSI1) suppression of RAS2(G19V) is independent of chromatin assembly factor I and mediated by NPR1. Molecular and Cellular Biology. 21: 1784-94. PMID 11238915 DOI: 10.1128/Mcb.21.5.1784-1794.2001  0.339
2000 Wu J, Tolstykh T, Lee J, Boyd K, Stock JB, Broach JR. Carboxyl methylation of the phosphoprotein phosphatase 2A catalytic subunit promotes its functional association with regulatory subunits in vivo. The Embo Journal. 19: 5672-81. PMID 11060018 DOI: 10.1093/Emboj/19.21.5672  0.358
1999 Meluh PB, Broach JR. Immunological analysis of yeast chromatin. Methods in Enzymology. 304: 414-30. PMID 10372374 DOI: 10.1016/S0076-6879(99)04025-2  0.301
1999 Jiang Y, Broach JR. Tor proteins and protein phosphatase 2A reciprocally regulate Tap42 in controlling cell growth in yeast. The Embo Journal. 18: 2782-92. PMID 10329624 DOI: 10.1093/Emboj/18.10.2782  0.354
1999 Bi X, Broach JR. UAS(rpg) can function as a heterochromatin boundary element in yeast Genes and Development. 13: 1089-1101. PMID 10323861 DOI: 10.1101/Gad.13.9.1089  0.352
1999 Jiang Y, Davis C, Broach JR. Efficient transition to growth on fermentable carbon sources in Saccharomyces cerevisiae requires signaling through the Ras pathway. The Embo Journal. 17: 6942-51. PMID 9843500 DOI: 10.1093/Emboj/17.23.6942  0.326
1998 Mandala SM, Thornton R, Tu Z, Kurtz MB, Nickels J, Broach J, Menzeleev R, Spiegel S. Sphingoid base 1-phosphate phosphatase: a key regulator of sphingolipid metabolism and stress response. Proceedings of the National Academy of Sciences of the United States of America. 95: 150-5. PMID 9419344 DOI: 10.1073/Pnas.95.1.150  0.346
1997 Bi X, Broach JR. DNA in transcriptionally silent chromatin assumes a distinct topology that is sensitive to cell cycle progression Molecular and Cellular Biology. 17: 7077-7087. PMID 9372939 DOI: 10.1128/Mcb.17.12.7077  0.349
1997 Szeto L, Fafalios MK, Zhong H, Vershon AK, Broach JR. α2p controls donor preference during mating type interconversion in yeast by inactivating a recombinational enhancer of chromosome III Genes and Development. 11: 1899-1911. PMID 9271114 DOI: 10.1101/Gad.11.15.1899  0.329
1997 Szeto L, Broach JR. Role of alpha2 protein in donor locus selection during mating type interconversion. Molecular and Cellular Biology. 17: 751-9. PMID 9001229 DOI: 10.1128/Mcb.17.2.751  0.359
1996 Holmes SG, Broach JR. Silencers are required for inheritance of the repressed state in yeast Genes and Development. 10: 1021-1032. PMID 8608937 DOI: 10.1101/Gad.10.8.1021  0.332
1996 Nickels JT, Broach JR. A ceramide-activated protein phosphatase mediates ceramide-induced G1 arrest of Saccharomyces cerevisiae Genes and Development. 10: 382-394. PMID 8600023 DOI: 10.1101/Gad.10.4.382  0.379
1996 Holmes SG, Braunstein M, Broach JR. Transcriptional Silencing of the Yeast Mating-type Genes Cold Spring Harbor Monograph Archive. 32: 467-487. DOI: 10.1101/087969490.32.467  0.371
1995 Shei GJ, Broach JR. Yeast silencers can act as orientation-dependent gene inactivation centers that respond to environmental signals. Molecular and Cellular Biology. 15: 3496-506. PMID 7791756 DOI: 10.1128/Mcb.15.7.3496  0.373
1995 Neuman-Silberberg FS, Bhattacharya S, Broach JR. Nutrient availability and the RAS/cyclic AMP pathway both induce expression of ribosomal protein genes in Saccharomyces cerevisiae but by different mechanisms. Molecular and Cellular Biology. 15: 3187-96. PMID 7760815 DOI: 10.1128/Mcb.15.6.3187  0.422
1995 Bhattacharya S, Chen L, Broach JR, Powers S. Ras membrane targeting is essential for glucose signaling but not for viability in yeast. Proceedings of the National Academy of Sciences of the United States of America. 92: 2984-8. PMID 7708760 DOI: 10.1073/Pnas.92.7.2984  0.348
1994 Robinson MK, van Zyl WH, Phizicky EM, Broach JR. TPD1 of Saccharomyces cerevisiae encodes a protein phosphatase 2C-like activity implicated in tRNA splicing and cell separation. Molecular and Cellular Biology. 14: 3634-45. PMID 8196609 DOI: 10.1128/Mcb.14.6.3634  0.391
1993 Braunstein M, Rose AB, Holmes SG, Allis CD, Broach JR. Transcriptional silencing in yeast is associated with reduced nucleosome acetylation. Genes & Development. 7: 592-604. PMID 8458576 DOI: 10.1101/Gad.7.4.592  0.361
1992 Broach JR. Ras-regulated signaling processes in Saccharomyces cerevisiae. Current Opinion in Genetics & Development. 1: 370-7. PMID 1668647 DOI: 10.1016/S0959-437X(05)80302-8  0.332
1992 Russo FD, Scherson I, Broach JR. Direct simulation of yeast 2-microns circle plasmid amplification. Journal of Theoretical Biology. 155: 369-85. PMID 1619957 DOI: 10.1016/S0022-5193(05)80604-6  0.3
1992 Van Zyl W, Huang W, Sneddon AA, Stark M, Camier S, Werner M, Marck C, Sentenac A, Broach JR. Inactivation of the protein phosphatase 2A regulatory subunit a results in morphological and transcriptional defects in Saccharomyces cerevisiae Molecular and Cellular Biology. 12: 4946-4959. PMID 1328868 DOI: 10.1128/Mcb.12.11.4946  0.343
1991 Garrett S, Menold MM, Broach JR. The Saccharomyces cerevisiae YAK1 gene encodes a protein kinase that is induced by arrest early in the cell cycle. Molecular and Cellular Biology. 11: 4045-52. PMID 2072907 DOI: 10.1128/mcb.11.8.4045-4052.1991  0.35
1991 Jones S, Vignais ML, Broach JR. The CDC25 protein of Saccharomyces cerevisiae promotes exchange of guanine nucleotides bound to ras. Molecular and Cellular Biology. 11: 2641-6. PMID 2017169 DOI: 10.1128/Mcb.11.5.2641  0.372
1991 Mahoney DJ, Marquardt R, Shei GJ, Rose AB, Broach JR. Mutations in the HML E silencer of Saccharomyces cerevisiae yield metastable inheritance of transcriptional repression. Genes & Development. 5: 605-15. PMID 2010086 DOI: 10.1101/Gad.5.4.605  0.367
1991 Rose MD, Broach JR. Cloning genes by complementation in yeast. Methods in Enzymology. 194: 195-230. PMID 2005788 DOI: 10.1016/0076-6879(91)94017-7  0.368
1991 Dubey DD, Davis LR, Greenfeder SA, Ong LY, Zhu JG, Broach JR, Newlon CS, Huberman JA. Evidence suggesting that the ARS elements associated with silencers of the yeast mating-type locus HML do not function as chromosomal DNA replication origins. Molecular and Cellular Biology. 11: 5346-55. PMID 1922050 DOI: 10.1128/Mcb.11.10.5346  0.302
1991 Broach JR. RAS genes in Saccharomyces cerevisiae: signal transduction in search of a pathway. Trends in Genetics : Tig. 7: 28-33. PMID 1848378 DOI: 10.1016/0168-9525(91)90018-L  0.309
1991 Broach JR, Volkert FC. 6 Circular DNA Plasmids of Yeasts Cold Spring Harbor Monograph Archive. 297-331. DOI: 10.1101/087969363.21A.297  0.317
1990 Rose AB, Broach JR. Propagation and expression of cloned genes in yeast: 2-microns circle-based vectors. Methods in Enzymology. 185: 234-79. PMID 2199781 DOI: 10.1016/0076-6879(90)85024-I  0.304
1990 Fedor-Chaiken M, Deschenes RJ, Broach JR. SRV2, a gene required for RAS activation of adenylate cyclase in yeast Cell. 61: 329-340. PMID 2158860 DOI: 10.1016/0092-8674(90)90813-T  0.663
1990 Broach JR, Deschenes RJ. The function of ras genes in Saccharomyces cerevisiae Advances in Cancer Research. 54: 79-139. PMID 2153328 DOI: 10.1016/S0065-230X(08)60809-X  0.653
1990 Deschenes RJ, Resh MD, Broach JR. Acylation and prenylation of proteins Current Opinion in Cell Biology. 2: 1108-1113. PMID 2099805 DOI: 10.1016/0955-0674(90)90164-A  0.607
1989 Mahoney DJ, Broach JR. The HML mating-type cassette of Saccharomyces cerevisiae is regulated by two separate but functionally equivalent silencers. Molecular and Cellular Biology. 9: 4621-30. PMID 2689860 DOI: 10.1128/Mcb.9.11.4621  0.348
1989 Deschenes RJ, Stimmel JB, Clarke S, Stock J, Broach JR. RAS2 protein of Saccharomyces cerevisiae is methyl-esterified at its carboxyl terminus Journal of Biological Chemistry. 264: 11865-11873. PMID 2663844  0.609
1989 Garrett S, Broach J. Loss of Ras activity in Saccharomyces cerevisiae is suppressed by disruptions of a new kinase gene, YAKI, whose product may act downstream of the cAMP-dependent protein kinase Genes &Amp; Development. 3: 1336-1348. PMID 2558053 DOI: 10.1101/Gad.3.9.1336  0.378
1988 Marshall M, Mahoney D, Rose A, Hicks JB, Broach JR. Functional domains of SIR4, a gene required for position effect regulation in Saccharomyces cerevisiae. Molecular and Cellular Biology. 7: 4441-52. PMID 3325825 DOI: 10.1128/Mcb.7.12.4441  0.398
1988 Som T, Armstrong KA, Volkert FC, Broach JR. Autoregulation of 2μm circle gene expression provides a model for maintenance of stable plasmid copy levels Cell. 52: 27-37. PMID 2449970 DOI: 10.1016/0092-8674(88)90528-4  0.373
1987 Volkert FC, Wu LC, Fisher PA, Broach JR. Survival strategies of the yeast plasmid two-micron circle. Basic Life Sciences. 40: 375-96. PMID 3551916 DOI: 10.1007/978-1-4684-5251-8_29  0.345
1987 Deschenes RJ, Broach JR. Fatty acylation is important but not essential for Saccharomyces cerevisiae RAS function Molecular and Cellular Biology. 7: 2344-2351. PMID 3302674 DOI: 10.1128/Mcb.7.7.2344  0.653
1987 Brugge JS, Jarosik G, Andersen J, Queral-Lustig A, Fedor-Chaiken M, Broach JR. Expression of Rous sarcoma virus transforming protein pp60v-src in Saccharomyces cerevisiae cells Molecular and Cellular Biology. 7: 2180-2187. PMID 3037349 DOI: 10.1128/Mcb.7.6.2180  0.372
1986 Sutton A, Broach JR. Signals for transcription initiation and termination in the Saccharomyces cerevisiae plasmid 2 micron circle. Molecular and Cellular Biology. 5: 2770-80. PMID 3915534 DOI: 10.1128/Mcb.5.10.2770  0.357
1986 McLeod M, Craft S, Broach JR. Identification of the crossover site during FLP-mediated recombination in the Saccharomyces cerevisiae plasmid 2 microns circle Molecular and Cellular Biology. 6: 3357-3367. PMID 3540590 DOI: 10.1128/Mcb.6.10.3357  0.343
1986 Andrews BJ, McLeod M, Broach J, Sadowski PD. Interaction of the FLP recombinase of the Saccharomyces cerevisiae 2 micron plasmid with mutated target sequences. Molecular and Cellular Biology. 6: 2482-9. PMID 3537720 DOI: 10.1128/Mcb.6.7.2482  0.331
1986 Volkert FC, Broach JR. Site-specific recombination promotes plasmid amplification in yeast. Cell. 46: 541-50. PMID 3524855 DOI: 10.1016/0092-8674(86)90879-2  0.339
1985 Hicks J, Strathern J, Klar A, Ismail S, Broach J. Structure of the SAD mutation and the location of control sites at silent mating type genes in Saccharomyces cerevisiae. Molecular and Cellular Biology. 4: 1278-85. PMID 6095058 DOI: 10.1128/Mcb.4.7.1278  0.309
1985 Jayaram M, Sutton A, Broach JR. Properties of REP3: A cis-acting locus required for stable propagation of the Saccharomyces cerevisiae plasmid 2μm circle Molecular and Cellular Biology. 5: 2466-2475. PMID 3915543 DOI: 10.1128/mcb.5.9.2466-2475.1985  0.378
1985 Wishart WL, Broach JR, Ohtsubo E. ATP-dependent specific binding of Tn3 transposase to Tn3 inverted repeats. Nature. 314: 556-8. PMID 2986006 DOI: 10.1038/314556A0  0.302
1985 Toda T, Uno I, Ishikawa T, Powers S, Kataoka T, Broek D, Cameron S, Broach J, Matsumoto K, Wigler M. In yeast, RAS proteins are controlling elements of adenylate cyclase. Cell. 40: 27-36. PMID 2981630 DOI: 10.1016/0092-8674(85)90305-8  0.321
1985 Kataoka T, Powers S, Cameron S, Fasano O, Goldfarb M, Broach J, Wigler M. Functional homology of mammalian and yeast RAS genes. Cell. 40: 19-26. PMID 2981628 DOI: 10.1016/0092-8674(85)90304-6  0.355
1984 Powers S, Kataoka T, Fasano O, Goldfarb M, Strathern J, Broach J, Wigler M. Genes in S. cerevisiae encoding proteins with domains homologous to the mammalian ras proteins. Cell. 36: 607-12. PMID 6365329 DOI: 10.1016/0092-8674(84)90340-4  0.371
1984 Kataoka T, Powers S, McGill C, Fasano O, Strathern J, Broach J, Wigler M. Genetic analysis of yeast RAS1 and RAS2 genes. Cell. 37: 437-45. PMID 6327067 DOI: 10.1016/0092-8674(84)90374-X  0.371
1984 Feldman JB, Hicks JB, Broach JR. Identification of sites required for repression of a silent mating type locus in yeast. Journal of Molecular Biology. 178: 815-34. PMID 6092645 DOI: 10.1016/0022-2836(84)90313-9  0.377
1983 Jayaram M, Li YY, Broach JR. The yeast plasmid 2μ circle encodes components required for its high copy propagation Cell. 34: 95-104. PMID 6883512 DOI: 10.1016/0092-8674(83)90139-3  0.331
1983 Jayaram M, Broach JR. Yeast plasmide 2-μm circle promotes recombination within bacterial transposon Tn5 Proceedings of the National Academy of Sciences of the United States of America. 80: 7264-7268. PMID 6316350 DOI: 10.1073/Pnas.80.23.7264  0.314
1983 Broach JR. Construction of high copy yeast vectors using 2-microns circle sequences. Methods in Enzymology. 101: 307-25. PMID 6310334 DOI: 10.1016/0076-6879(83)01024-1  0.341
1982 Broach JR. The yeast plasmid 2 mu circle. Cell. 28: 203-4. PMID 7037198 DOI: 10.1016/0092-8674(82)90337-3  0.323
1982 Broach JR, Friedman L, Sherman F. Correspondence of yeast UAA suppressors to cloned tRNASerUCA genes. Journal of Molecular Biology. 150: 375-87. PMID 6795357 DOI: 10.1016/0022-2836(81)90553-2  0.535
1982 Broach JR, Guarascio VR, Jayaram M. Recombination within the yeast plasmid 2μ circle is site-specific Cell. 29: 227-234. PMID 6286142 DOI: 10.1016/0092-8674(82)90107-6  0.346
1981 Broach JR. APPENDIX III Genes of Saccharomyces cerevisiae Cold Spring Harbor Monograph Archive. 653-727. DOI: 10.1101/87969139.11A.653  0.324
1981 Broach JR. The Yeast Plasmid 2 μ Circle Cold Spring Harbor Monograph Archive. 445-470. DOI: 10.1101/87969139.11A.445  0.326
1981 Strathern JN, Jones EW, Broach JR. Preface/Front Matter Cold Spring Harbor Monograph Archive. DOI: 10.1101/087969180.11B.I  0.368
1980 Broach JR, Hicks JB. Replication and recombination functions associated with the yeast plasmid, 2 mu circle. Cell. 21: 501-8. PMID 7407923 DOI: 10.1016/0092-8674(80)90487-0  0.327
1980 Broach JR, Strathern JN, Hicks JB. Transformation in yeast: development of a hybrid cloning vector and isolation of the CAN1 gene. Gene. 8: 121-33. PMID 395029 DOI: 10.1016/0378-1119(79)90012-X  0.345
1979 Broach JR. Galactose regulation in Saccharomyces cerevisiae. The enzymes encoded by the GAL7, 10, 1 cluster are co-ordinately controlled and separately translated. Journal of Molecular Biology. 131: 41-53. PMID 385888 DOI: 10.1016/0022-2836(79)90300-0  0.346
1979 Broach JR, Atkins JF, McGill C, Chow L. Identification and mapping of the transcriptional and translational products of the yeast plasmid, 2mu circle. Cell. 16: 827-39. PMID 378400 DOI: 10.1016/0092-8674(79)90098-9  0.335
1978 Petes TD, Broach JR, Wensink PC, Hereford LM, Fink GR, Botstein D. Isolation and analysis of recombinant DNA molecules containing yeast DNA. Gene. 4: 37-49. PMID 365691 DOI: 10.1016/0378-1119(78)90013-6  0.496
1978 Hopper JE, Broach JR, Rowe LB. Regulation of the galactose pathway in Saccharomyces cerevisiae: Induction of uridyl transferase mRNA and dependency on GAL4 gene function Proceedings of the National Academy of Sciences of the United States of America. 75: 2878-2882. PMID 351620 DOI: 10.1073/Pnas.75.6.2878  0.37
1975 Cieslà Z, Salvatore F, Broach JR, Artz SW, Ames BN. Histidine regulation in Salmonella typhimurium. XVI. A sensitive radiochemical assay for histidinol dehydrogenase. Analytical Biochemistry. 63: 44-55. PMID 1089301 DOI: 10.1016/0003-2697(75)90187-6  0.417
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