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Maxime W. Rousseaux, Ph.D. - Publications

Affiliations: 
University of Ottawa, Ottawa, ON, Canada 
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Rousseaux MW, Revelli JP, Vázquez-Vélez GE, Kim JY, Craigen E, Gonzales K, Beckinghausen J, Zoghbi HY. Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau. Elife. 7. PMID 29863470 DOI: 10.7554/Elife.36768  0.771
2018 Rousseaux MW, Revelli J, Vázquez-Vélez GE, Kim J, Craigen E, Gonzales K, Beckinghausen J, Zoghbi HY. Author response: Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau Elife. DOI: 10.7554/Elife.36768.017  0.538
2017 Jeong HH, Kim SY, Rousseaux MW, Zoghbi HY, Liu Z. CRISPRcloud: A secure cloud-based pipeline for CRISPR pooled screen deconvolution. Bioinformatics (Oxford, England). PMID 28541456 DOI: 10.1093/Bioinformatics/Btx335  0.332
2017 Lu HC, Tan Q, Rousseaux MW, Wang W, Kim JY, Richman R, Wan YW, Yeh SY, Patel JM, Liu X, Lin T, Lee Y, Fryer JD, Han J, Chahrour M, et al. Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans. Nature Genetics. PMID 28288114 DOI: 10.1038/Ng.3808  0.744
2017 Jung SY, Choi JM, Rousseaux MW, Malovannaya A, Kim JJ, Kutzera J, Wang Y, Huang Y, Zhu W, Maity S, Zoghbi HY, Qin J. An anatomically resolved mouse brain proteome reveals Parkinson disease-relevant pathways. Molecular & Cellular Proteomics : McP. PMID 28153913 DOI: 10.1074/Mcp.M116.061440  0.459
2016 Rousseaux MW, de Haro M, Lasagna-Reeves CA, De Maio A, Park J, Jafar-Nejad P, Al-Ramahi I, Sharma A, See L, Lu N, Vilanova-Velez L, Klisch TJ, Westbrook TF, Troncoso JC, Botas J, et al. TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau. Elife. 5. PMID 27779468 DOI: 10.7554/Elife.19809  0.779
2016 Lasagna-Reeves CA, de Haro M, Hao S, Park J, Rousseaux MW, Al-Ramahi I, Jafar-Nejad P, Vilanova-Velez L, See L, De Maio A, Nitschke L, Wu Z, Troncoso JC, Westbrook TF, Tang J, et al. Reduction of Nuak1 Decreases Tau and Reverses Phenotypes in a Tauopathy Mouse Model. Neuron. PMID 27720485 DOI: 10.1016/J.Neuron.2016.09.022  0.785
2016 Rousseaux MW, Haro Md, Lasagna-Reeves CA, Maio AD, Park J, Jafar-Nejad P, Al-Ramahi I, Sharma A, See L, Lu N, Vilanova-Velez L, Klisch TJ, Westbrook TF, Troncoso JC, Botas J, et al. Author response: TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau Elife. DOI: 10.7554/Elife.19809.028  0.766
2015 Lasagna-Reeves CA, Rousseaux MW, Guerrero-Munoz MJ, Vilanova-Velez L, Park J, See L, Jafar-Nejad P, Richman R, Orr HT, Kayed R, Zoghbi HY. Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes. Elife. 4. PMID 26673892 DOI: 10.7554/Elife.10891  0.759
2015 Qu D, Hage A, Don-Carolis K, Huang E, Joselin A, Safarpour F, Marcogliese PC, Rousseaux MW, Hewitt SJ, Huang T, Im DS, Callaghan S, Dewar-Darch D, Figeys D, Slack RS, et al. Bag2 Mediated Regulation of Pink1 is Critical for Mitochondrial Translocation of Parkin and Neuronal Survival. The Journal of Biological Chemistry. PMID 26538564 DOI: 10.1074/Jbc.M115.677815  0.767
2015 Lasagna-Reeves CA, Rousseaux MW, Guerrero-Muñoz MJ, Park J, Jafar-Nejad P, Richman R, Lu N, Sengupta U, Litvinchuk A, Orr HT, Kayed R, Zoghbi HY. A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1. Elife. 4. PMID 25988806 DOI: 10.7554/Elife.07558  0.777
2015 Rousseaux MW, Zoghbi HY. Deep brain stimulation for Parkinson disease: the 2014 Lasker-DeBakey Clinical Medical Research Award. Jama Neurology. 72: 259-60. PMID 25560048 DOI: 10.1001/jamaneurol.2014.4109  0.389
2015 Lasagna-Reeves CA, Rousseaux MW, Guerrero-Munoz MJ, Vilanova-Velez L, Park J, See L, Jafar-Nejad P, Richman R, Orr HT, Kayed R, Zoghbi HY. Author response: Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes Elife. DOI: 10.7554/Elife.10891.010  0.745
2015 Lasagna-Reeves CA, Rousseaux MW, Guerrero-Muñoz MJ, Park J, Jafar-Nejad P, Richman R, Lu N, Sengupta U, Litvinchuk A, Orr HT, Kayed R, Zoghbi HY. Author response: A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1 Elife. DOI: 10.7554/Elife.07558.025  0.744
2015 Rousseaux M, de Haro M, Lasagna-Reeves C, De Maio A, Jafar-Nejad P, Park J, Al-Ramahi I, Kayed R, Botas H, Zoghbi H. TRIM28 regulates the stability and toxicity of alpha-synuclein and tau through a common mechanism Journal of the Neurological Sciences. 357: e285-e286. DOI: 10.1016/J.Jns.2015.08.996  0.766
2015 Lasagna-Reeves C, Al Ramahi I, de Haro M, Rousseaux M, Kim J, Jafar-Nejad P, Vilanova-Velez L, Westbrook T, Botas J, Zoghbi H. Targeting tau protein stability in alzheimer disease to identify novel therapeutic entry points Journal of the Neurological Sciences. 357: e131. DOI: 10.1016/J.Jns.2015.08.422  0.779
2014 Parsanejad M, Bourquard N, Qu D, Zhang Y, Huang E, Rousseaux MW, Aleyasin H, Irrcher I, Callaghan S, Vaillant DC, Kim RH, Slack RS, Mak TW, Reddy ST, Figeys D, et al. DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress. Plos One. 9: e106601. PMID 25210784 DOI: 10.1371/Journal.Pone.0106601  0.78
2014 Parsanejad M, Zhang Y, Qu D, Irrcher I, Rousseaux MW, Aleyasin H, Kamkar F, Callaghan S, Slack RS, Mak TW, Lee S, Figeys D, Park DS. Regulation of the VHL/HIF-1 pathway by DJ-1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8043-50. PMID 24899725 DOI: 10.1523/Jneurosci.1244-13.2014  0.793
2012 Rousseaux MW, Marcogliese PC, Qu D, Hewitt SJ, Seang S, Kim RH, Slack RS, Schlossmacher MG, Lagace DC, Mak TW, Park DS. Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson disease. Proceedings of the National Academy of Sciences of the United States of America. 109: 15918-23. PMID 23019375 DOI: 10.1073/Pnas.1205102109  0.75
2010 Irrcher I, Aleyasin H, Seifert EL, Hewitt SJ, Chhabra S, Phillips M, Lutz AK, Rousseaux MW, Bevilacqua L, Jahani-Asl A, Callaghan S, MacLaurin JG, Winklhofer KF, Rizzu P, Rippstein P, et al. Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics. Human Molecular Genetics. 19: 3734-46. PMID 20639397 DOI: 10.1093/Hmg/Ddq288  0.745
2010 Huang E, Qu D, Zhang Y, Venderova K, Haque ME, Rousseaux MW, Slack RS, Woulfe JM, Park DS. The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death. Nature Cell Biology. 12: 563-71. PMID 20473298 DOI: 10.1038/Ncb2058  0.529
2010 Aleyasin H, Rousseaux MW, Marcogliese PC, Hewitt SJ, Irrcher I, Joselin AP, Parsanejad M, Kim RH, Rizzu P, Callaghan SM, Slack RS, Mak TW, Park DS. DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway. Proceedings of the National Academy of Sciences of the United States of America. 107: 3186-91. PMID 20133695 DOI: 10.1073/Pnas.0914876107  0.762
2010 Zhang Y, Parsanejad M, Huang E, Qu D, Aleyasin H, Rousseaux MW, Gonzalez YR, Cregan SP, Slack RS, Park DS. Pim-1 kinase as activator of the cell cycle pathway in neuronal death induced by DNA damage. Journal of Neurochemistry. 112: 497-510. PMID 19895669 DOI: 10.1111/J.1471-4159.2009.06476.X  0.765
2009 Rashidian J, Rousseaux MW, Venderova K, Qu D, Callaghan SM, Phillips M, Bland RJ, During MJ, Mao Z, Slack RS, Park DS. Essential role of cytoplasmic cdk5 and Prx2 in multiple ischemic injury models, in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12497-505. PMID 19812325 DOI: 10.1523/Jneurosci.3892-09.2009  0.54
2007 Aleyasin H, Rousseaux MW, Phillips M, Kim RH, Bland RJ, Callaghan S, Slack RS, During MJ, Mak TW, Park DS. The Parkinson's disease gene DJ-1 is also a key regulator of stroke-induced damage. Proceedings of the National Academy of Sciences of the United States of America. 104: 18748-53. PMID 18003894 DOI: 10.1073/Pnas.0709379104  0.731
2007 Qu D, Rashidian J, Mount MP, Aleyasin H, Parsanejad M, Lira A, Haque E, Zhang Y, Callaghan S, Daigle M, Rousseaux MW, Slack RS, Albert PR, Vincent I, Woulfe JM, et al. Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease. Neuron. 55: 37-52. PMID 17610816 DOI: 10.1016/J.Neuron.2007.05.033  0.787
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