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William C. Summers - Publications

Affiliations: 
Therapeutic Radiology Yale University, New Haven, CT 
Area:
History of molecular biology
Website:
http://medicine.yale.edu/mbb/faculty/william_summers.profile
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61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
1998 Champness JN, Bennett MS, Wien F, Visse R, Summers WC, Herdewijn P, de Clerq E, Ostrowski T, Jarvest RL, Sanderson MR. Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands. Proteins. 32: 350-61. PMID 9715911 DOI: 10.1002/(Sici)1097-0134(19980815)32:3<350::Aid-Prot10>3.0.Co;2-8  0.317
1997 Evans JS, Lock KP, Levine BA, Champness JN, Sanderson MR, Summers WC, Buchan A. Structure-specificity features of HSV-1 thymidine kinases. Biochemical Society Transactions. 25: S621. PMID 9450049 DOI: 10.1042/Bst025S621  0.306
1993 Young DM, Summers WC, Cuono CB. Chemiluminescent restriction fragment length polymorphism analysis (DNA fingerprinting) to identify keratinocytes from two donors in co-culture. Experimental Dermatology. 2: 25-8. PMID 7908840 DOI: 10.1111/J.1600-0625.1993.Tb00195.X  0.313
1990 Kupfer SR, Summers WC. Identification of a glucocorticoid-responsive element in Epstein-Barr virus. Journal of Virology. 64: 1984-90. PMID 2157866 DOI: 10.1128/Jvi.64.5.1984-1990.1990  0.349
1989 Glazer PM, Greggio NA, Metherall JE, Summers WC. UV-induced DNA-binding proteins in human cells. Proceedings of the National Academy of Sciences of the United States of America. 86: 1163-7. PMID 2919165 DOI: 10.1073/Pnas.86.4.1163  0.557
1989 Liu QY, Summers WC. Novel 12-O-tetradecanoylphorbol-13-acetate-responsive elements in the upstream sequence of the MS gene promoter of Epstein-Barr virus. Journal of Virology. 63: 5062-8. PMID 2555542 DOI: 10.1128/Jvi.63.12.5062-5068.1989  0.317
1989 D'Aquila RT, Hayward GS, Summers WC. Physical mapping of the human cytomegalovirus (HCMV) (Towne) DNA polymerase gene: DNA-mediated transfer of a genetic marker for an HCMV gene. Virology. 171: 312-6. PMID 2545037 DOI: 10.1016/0042-6822(89)90546-1  0.416
1989 Summers WC, Glazer PM, Malkevich D. Lambda phage shuttle vectors for analysis of mutations in mammalian cells in culture and in transgenic mice. Mutation Research. 220: 263-8. PMID 2522589 DOI: 10.1016/0165-1110(89)90030-4  0.568
1987 Lacy J, Summers WP, Watson M, Glazer PM, Summers WC. Amplification and deregulation of MYC following Epstein-Barr virus infection of a human B-cell line. Proceedings of the National Academy of Sciences of the United States of America. 84: 5838-42. PMID 3039510 DOI: 10.1073/Pnas.84.16.5838  0.525
1987 Glazer PM, Sarkar SN, Chisholm GE, Summers WC. DNA mismatch repair detected in human cell extracts. Molecular and Cellular Biology. 7: 218-24. PMID 3031461 DOI: 10.1128/Mcb.7.1.218  0.563
1987 D'Aquila RT, Summers WC. Isolation and characterization of phosphonoacetic acid-resistant mutants of human cytomegalovirus. Journal of Virology. 61: 1291-5. PMID 3029427 DOI: 10.1128/Jvi.61.4.1291-1295.1987  0.351
1986 Glazer PM, Sarkar SN, Summers WC. Detection and analysis of UV-induced mutations in mammalian cell DNA using a lambda phage shuttle vector. Proceedings of the National Academy of Sciences of the United States of America. 83: 1041-4. PMID 2937054 DOI: 10.1073/Pnas.83.4.1041  0.601
1985 Haarr L, Marsden HS, Preston CM, Smiley JR, Summers WC, Summers WP. Utilization of internal AUG codons for initiation of protein synthesis directed by mRNAs from normal and mutant genes encoding herpes simplex virus-specified thymidine kinase. Journal of Virology. 56: 512-9. PMID 2997472 DOI: 10.1128/Jvi.56.2.512-519.1985  0.368
1985 Glazer PM, Summers WC. Oncogene expression in isogenic, EBV-positive and -negative Burkitt lymphoma cell lines. Intervirology. 23: 82-9. PMID 2984143 DOI: 10.1159/000149589  0.501
1984 Read GS, Sharp JA, Summers WC. In vitro and in vivo transcription initiation sites on the TK-encoding BamHI Q fragment of HSV-1 DNA. Virology. 138: 368-72. PMID 6093373 DOI: 10.1016/0042-6822(84)90363-5  0.452
1983 Sharp JA, Wagner MJ, Summers WC. Transcription of herpes simplex virus genes in vivo: overlap of a late promoter with the 3' end of the early thymidine kinase gene. Journal of Virology. 45: 10-7. PMID 6296424 DOI: 10.1128/Jvi.45.1.10-17.1983  0.372
1982 Read GS, Summers WC. In vitro transcription of the thymidine kinase gene of herpes simplex virus. Proceedings of the National Academy of Sciences of the United States of America. 79: 5215-9. PMID 6291032  0.352
1981 Fischer DK, Miller G, Gradoville L, Heston L, Westrate MW, Maris W, Wright J, Brandsma J, Summers WC. Genome of a mononucleosis Epstein-Barr virus contains DNA fragments previously regarded to be unique to Burkitt's lymphoma isolates. Cell. 24: 543-53. PMID 6263500 DOI: 10.1016/0092-8674(81)90345-7  0.364
1981 Wagner MJ, Sharp JA, Summers WC. Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1. Proceedings of the National Academy of Sciences of the United States of America. 78: 1441-5. PMID 6262799 DOI: 10.1073/Pnas.78.3.1441  0.345
1980 Leinbach SS, Summers WC. The structure of herpes simplex virus type 1 DNA as probed by micrococcal nuclease digestion. The Journal of General Virology. 51: 45-59. PMID 6257837 DOI: 10.1099/0022-1317-51-1-45  0.426
1980 Dasgupta UB, Summers WC. Genetic recombination of herpes simplex virus, the role of the host cell and UV-irradiation of the virus. Molecular & General Genetics : Mgg. 178: 617-23. PMID 6248734 DOI: 10.1007/Bf00337869  0.329
1980 Summers WC. Molecular epidemiology of DNA viruses: applications of restriction endonuclease cleavage site analysis. The Yale Journal of Biology and Medicine. 53: 55-9. PMID 6246687  0.313
1980 Smiley JR, Wagner MJ, Summers WP, Summers WC. Genetic and physical evidence for the polarity of transcription of the thymidine kinase gene of herpes simplex virus. Virology. 102: 83-93. PMID 6245510 DOI: 10.1016/0042-6822(80)90072-0  0.391
1979 Enquist LW, Vande Woude GF, Wagner M, Smiley JR, Summers WC. Construction and characterization of a recombinant plasmid encoding the gene for the thymidine kinase of Herpes simplex type 1 virus. Gene. 7: 335-42. PMID 230124 DOI: 10.1016/0378-1119(79)90052-0  0.441
1979 Leinbach SS, Summers WC. Herpes simplex virus type 1 infection of isogenic Epstein-Barr virus genome-negative and -positive Burkitt's lymphoma-derived cell lines. Journal of Virology. 30: 248-54. PMID 225521 DOI: 10.1128/Jvi.30.1.248-254.1979  0.345
1979 Cremer KJ, Bodemer M, Summers WP, Summers WC, Gesteland RF. In vitro suppression of UAG and UGA mutants in the thymidine kinase gene of herpes simplex virus. Proceedings of the National Academy of Sciences of the United States of America. 76: 430-4. PMID 218201 DOI: 10.1073/Pnas.76.1.430  0.328
1978 Cremer K, Bodemer M, Summers WC. Characterization of the mRNA for herpes simplex virus thymidine kinase by cell-free synthesis of active enzyme. Nucleic Acids Research. 5: 2333-44. PMID 209407 DOI: 10.1093/Nar/5.7.2333  0.329
1977 Cremer KJ, Summers WC, Gesteland RF. Cell-free synthesis of herpes simplex virus proteins. Journal of Virology. 22: 750-7. PMID 195089 DOI: 10.1128/Jvi.22.3.750-757.1977  0.323
1977 Skare J, Summers WC. Structure and function of herpesvirus genomes. II. EcoRl, Sbal, and HindIII endonuclease cleavage sites on herpes simplex virus. Virology. 76: 581-95. PMID 190767 DOI: 10.1016/0042-6822(77)90240-9  0.698
1976 Ludwig RA, Summers WC. Localization of RNA polymerase binding sites on T7 DNA. Virology. 71: 278-90. PMID 775764 DOI: 10.1016/0042-6822(76)90112-4  0.711
1976 Sugden B, Summers WC, Klein G. Nucleic acid renaturation and restriction endonuclease cleavage analyses show that the DNAs of a transforming and a nontransforming strain of Epstein-Barr virus share approximately 90% of their nucleotide sequences. Journal of Virology. 18: 765-75. PMID 178907 DOI: 10.1128/Jvi.18.2.765-775.1976  0.327
1975 Ludwig RA, Summers WC. A restriction fragment analysis of the T7 left-early region. Virology. 68: 360-73. PMID 1081780 DOI: 10.1016/0042-6822(75)90279-2  0.699
1975 Wagner M, Skare J, Summers WC. Analysis of DNA of defective herpes simplex virus type 1 by restriction endonuclease cleavage and nucleic acid hybridization. Cold Spring Harbor Symposia On Quantitative Biology. 39: 683-6. PMID 169024 DOI: 10.1101/Sqb.1974.039.01.082  0.38
1975 Skare J, Summers WP, Summers WC. Structure and function of herpesvirus genomes. I. comparison of five HSV-1 and two HSV-2 strains by cleavage their DNA with eco R I restriction endonuclease. Journal of Virology. 15: 726-32. PMID 163917 DOI: 10.1128/Jvi.15.4.726-732.1975  0.334
1974 Skare J, Niles EG, Summers WC. Localization of the leftmost initiation site for T7 late transcription, in vivo and in vitro. Biochemistry. 13: 3912-6. PMID 4606770 DOI: 10.1021/Bi00716A015  0.691
1974 Hyman RW, Brunovskis I, Summers WC. A biochemical comparison of the related bacteriophages T7, phiI, phiII, W31, H, and T3. Virology. 57: 189-206. PMID 4594468 DOI: 10.1016/0042-6822(74)90120-2  0.408
1973 Hyman RW, Brunovskis I, Summers WC. DNA base sequence homology between coliphages T7 and phiII and between T3 and phiII as determined by heteroduplex mapping in the electron microscope. Journal of Molecular Biology. 77: 189-96. PMID 4765359 DOI: 10.1016/0022-2836(73)90330-6  0.451
1973 Summers WC, Brunovskis I, Hyman RW. The process of infection with coliphage T7. VII. Characterization and mapping of the major in vivo transcription products of the early region. Journal of Molecular Biology. 74: 291-300. PMID 4571232 DOI: 10.1016/0022-2836(73)90374-4  0.381
1972 Summers WC. Regulation of RNA metabolism of T7 and related phages. Annual Review of Genetics. 6: 191-202. PMID 4581486 DOI: 10.1146/Annurev.Ge.06.120172.001203  0.463
1972 Hyman RW, Summers WC. Isolation and physical mapping of T7 gene 1 messenger RNA. Journal of Molecular Biology. 71: 573-82. PMID 4567467 DOI: 10.1016/S0022-2836(72)80024-X  0.461
1972 Brunovskis I, Summers WC. The process of infection with coliphage 17. VI. A phage gene controlling shutoff of host RNA synthesis. Virology. 50: 322-7. PMID 4564521 DOI: 10.1016/0042-6822(72)90383-2  0.37
1971 Summers WC, Jakes K. Phage T7 lysozyme mRNA transcription and translation in vivo and in vitro. Biochemical and Biophysical Research Communications. 45: 315-20. PMID 4946267 DOI: 10.1016/0006-291X(71)90820-5  0.371
1971 Brunovskis I, Summers WC. The process of infection with coliphage T7. V. Shutoff of host RNA synthesis by an early phage function. Virology. 45: 224-31. PMID 4939451 DOI: 10.1016/0042-6822(71)90129-2  0.365
1971 Szybalski W, Kubinski H, Hradecna Z, Summers WC. [30] Analytical and preparative separation of the complementary DNA strands Methods in Enzymology. 21: 383-413. DOI: 10.1016/S0076-6879(71)21032-6  0.574
1970 Summers WC, Siegel RB. Transcription of late phage RNA by T7 RNA polymerase. Nature. 228: 1160-2. PMID 5487240 DOI: 10.1038/2281160A0  0.698
1970 Linial M, Malamy MH, Summers WC. Separation of the complementary strands and asymmetric in vivo transcription of coliphage phiII DNA. Virology. 41: 766-7. PMID 5474464 DOI: 10.1016/0042-6822(70)90442-3  0.429
1970 Chessin H, Summers WC. Initiation by RNA polymerase on UV or X-ray damaged T7 DNA Biochemical and Biophysical Research Communications. 38: 40-45. PMID 5418690 DOI: 10.1016/0006-291X(70)91080-6  0.454
1970 Maher VM, Summers WC. Mutagenic action of aflatoxin B1 on transforming DNA and inhibition of DNA template activity in vitro Nature. 225: 68-70. PMID 4983028 DOI: 10.1038/225068A0  0.388
1970 Siegel RB, Summers WC. The process of infection with coliphage T7. III. Control of phage-specific RNA synthesis in vivo by an early phage gene Journal of Molecular Biology. 49: 115-123. PMID 4915857 DOI: 10.1016/0022-2836(70)90380-3  0.693
1970 Summers WC. The process of infection with coliphage T7. IV. Stability of RNA in bacteriophage-infected cells. Journal of Molecular Biology. 51: 671-8. PMID 4099510 DOI: 10.1016/0022-2836(70)90015-X  0.392
1970 Summers WC, Siegel RB. Regulation of Coliphage T7 RNA Metabolism in vivo and in vitro Cold Spring Harbor Symposia On Quantitative Biology. 35: 253-257. DOI: 10.1101/Sqb.1970.035.01.034  0.663
1969 Summers WC. Effect of size and aggregation of guanine-rich polyribonucleotides on the practical aspects of DNA strand separation in CsCl density gradients Bba Section Nucleic Acids and Protein Synthesis. 182: 269-272. PMID 5792856 DOI: 10.1016/0005-2787(69)90548-6  0.334
1969 Summers WC. The process of infection with coliphage T7. I. Characterization of T7 RNA by polyacrylamide gel electrophoretic analysis Virology. 39: 175-182. PMID 5344283 DOI: 10.1016/0042-6822(69)90037-3  0.407
1969 Szybalski W, Bovre K, Fiandt M, Guha A, Hradecna Z, Kumar S, Lozeron HA, Maher VM, Nijkamp HJ, Summers WC, Taylor K. Transcriptional controls in developing bacteriophages. Journal of Cellular Physiology. 74: Suppl 1:33-70. PMID 4902822 DOI: 10.1002/Jcp.1040740405  0.617
1969 Summers WC, Sielgel RB. Control of template specificity of E. Coli RNA polymerase by a phage-coded protein Nature. 223: 1111-1113. PMID 4897557 DOI: 10.1038/2231111A0  0.434
1968 Summers WC, Szybalski W. Totally asymmetric transcription of coliphage T7 in vivo: correlation with poly G binding sites. Virology. 34: 9-16. PMID 18614103 DOI: 10.1016/0042-6822(68)90003-2  0.626
1968 Summers WC, Szybalski W. Size, number, and distribution of poly G binding sites on the separated DNA strands of coliphage T7. Biochimica Et Biophysica Acta. 166: 371-8. PMID 5680597 DOI: 10.1016/0005-2787(68)90224-4  0.612
1968 Summers WC. Equal transfer of both parental T7 DNA strands to progeny bacteriophage [14] Nature. 219: 159-160. DOI: 10.1038/219159A0  0.391
1967 Summers WC, Szybalski W. Gamma-irradiation of deoxyribonucleic acid in dilute solutions. I. A sensitive method for detection of single-strand breaks in polydisperse DNA samples. Journal of Molecular Biology. 26: 107-23. PMID 4962560 DOI: 10.1016/0022-2836(67)90264-1  0.57
1967 Summers WC, Szybalski W. Gamma-irradiation of deoxyribonucleic acid in dilute solutions. II. Molecular mechanisms responsible for inactivation of phage, its transfecting DNA, and of bacterial transforming activity. Journal of Molecular Biology. 26: 227-35. PMID 4962270 DOI: 10.1016/0022-2836(67)90293-8  0.591
1967 Summers WC. Analysis of cross-link distribution in polydisperse DNA samples Journal of Molecular Biology. 26: 122-123. DOI: 10.1016/0022-2836(67)90265-3  0.308
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