Year |
Citation |
Score |
2024 |
Rajagopal BS, Yates N, Smith J, Paradisi A, Tétard-Jones C, Willats WGT, Marcus S, Knox JP, Firdaus-Raih M, Henrissat B, Davies GJ, Walton PH, Parkin A, Hemsworth GR. Structural dissection of two redox proteins from the shipworm symbiont Teredinibacter turnerae. Iucrj. 11: 260-274. PMID 38446458 DOI: 10.1107/S2052252524001386 |
0.615 |
|
2023 |
McGregor NGS, de Boer C, Foucart QPO, Beenakker T, Offen WA, Codée JDC, Willems LI, Overkleeft HS, Davies GJ. A Multiplexing Activity-Based Protein-Profiling Platform for Dissection of a Native Bacterial Xyloglucan-Degrading System. Acs Central Science. 9: 2306-2314. PMID 38161374 DOI: 10.1021/acscentsci.3c00831 |
0.318 |
|
2023 |
Calvelo M, Males A, Alteen MG, Willems LI, Vocadlo DJ, Davies GJ, Rovira C. Human -GlcNAcase Uses a Preactivated Boat-skew Substrate Conformation for Catalysis. Evidence from X-ray Crystallography and QM/MM Metadynamics. Acs Catalysis. 13: 13672-13678. PMID 37969138 DOI: 10.1021/acscatal.3c02378 |
0.382 |
|
2023 |
Snow AJD, Sharma M, Abayakoon P, Williams SJ, Blaza JN, Davies GJ. Structure and mechanism of sulfofructose transaldolase, a key enzyme in sulfoquinovose metabolism. Structure (London, England : 1993). 31: 244-252.e4. PMID 36805128 DOI: 10.1016/j.str.2023.01.010 |
0.351 |
|
2023 |
Walton PH, Davies GJ, Diaz DE, Franco-Cairo JP. The Histidine Brace: Nature's Copper Alternative to Haem? Febs Letters. PMID 36660911 DOI: 10.1002/1873-3468.14579 |
0.59 |
|
2022 |
Walton PH, Davies GJ. Structural perturbations of substrate binding and oxidation state changes in a lytic polysaccharide monooxygenase. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 36208326 DOI: 10.1007/s00775-022-01966-z |
0.645 |
|
2022 |
Franco Cairo JPL, Mandelli F, Tramontina R, Cannella D, Paradisi A, Ciano L, Ferreira MR, Liberato MV, Brenelli LB, Gonçalves TA, Rodrigues GN, Alvarez TM, Mofatto LS, Carazzolle MF, Pradella JGC, ... ... Davies GJ, et al. Oxidative cleavage of polysaccharides by a termite-derived boosts the degradation of biomass by glycoside hydrolases. Green Chemistry : An International Journal and Green Chemistry Resource : Gc. 24: 4845-4858. PMID 35813357 DOI: 10.1039/d1gc04519a |
0.811 |
|
2022 |
Terrasan CRF, Rubio MV, Gerhardt JA, Cairo JPF, Contesini FJ, Zubieta MP, Figueiredo FL, Valadares FL, Corrêa TLR, Murakami MT, Franco TT, Davies GJ, Walton PH, Damasio A. Deletion of AA9 Lytic Polysaccharide Monooxygenases Impacts A. nidulans Secretome and Growth on Lignocellulose. Microbiology Spectrum. e0212521. PMID 35658600 DOI: 10.1128/spectrum.02125-21 |
0.647 |
|
2022 |
McGregor NGS, de Boer C, Santos M, Haon M, Navarro D, Schroder S, Berrin JG, Overkleeft HS, Davies GJ. Activity-based protein profiling reveals dynamic substrate-specific cellulase secretion by saprotrophic basidiomycetes. Biotechnology For Biofuels and Bioproducts. 15: 6. PMID 35418096 DOI: 10.1186/s13068-022-02107-z |
0.31 |
|
2022 |
Lindley PJ, Parkin A, Davies GJ, Walton PH. Mapping the protonation states of the histidine brace in an AA10 lytic polysaccharide monooxygenase using CW-EPR spectroscopy and DFT calculations. Faraday Discussions. PMID 35171174 DOI: 10.1039/d1fd00068c |
0.577 |
|
2022 |
González-Cuesta M, Sidhu P, Ashmus RA, Males A, Proceviat C, Madden Z, Rogalski JC, Busmann JA, Foster LJ, García Fernández JM, Davies GJ, Ortiz Mellet C, Vocadlo DJ. Bicyclic Picomolar OGA Inhibitors Enable Chemoproteomic Mapping of Its Endogenous Post-translational Modifications. Journal of the American Chemical Society. 144: 832-844. PMID 34985906 DOI: 10.1021/jacs.1c10504 |
0.324 |
|
2021 |
Sabbadin F, Urresti S, Henrissat B, Avrova AO, Welsh LRJ, Lindley PJ, Csukai M, Squires JN, Walton PH, Davies GJ, Bruce NC, Whisson SC, McQueen-Mason SJ. Secreted pectin monooxygenases drive plant infection by pathogenic oomycetes. Science (New York, N.Y.). 373: 774-779. PMID 34385392 DOI: 10.1126/science.abj1342 |
0.559 |
|
2021 |
Overkleeft HS, Schröder S, Offen W, Males A, Jin Y, de Boer C, Enotarpi J, van der Marel G, Florea B, Codée J, Davies G. The Development of Non-Hydrolysable Oligosaccharide Activity-Based Inactivators for Endoglycanases: A Case Study on a-1,6 Mannanases. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 33878235 DOI: 10.1002/chem.202101255 |
0.514 |
|
2021 |
Sharma M, Abayakoon P, Epa R, Jin Y, Lingford JP, Shimada T, Nakano M, Mui JW, Ishihama A, Goddard-Borger ED, Davies GJ, Williams SJ. Molecular Basis of Sulfosugar Selectivity in Sulfoglycolysis. Acs Central Science. 7: 476-487. PMID 33791429 DOI: 10.1021/acscentsci.0c01285 |
0.446 |
|
2021 |
Moroz OV, Blagova E, Taylor E, Turkenburg JP, Skov LK, Gippert GP, Schnorr KM, Ming L, Ye L, Klausen M, Cohn MT, Schmidt EGW, Nymand-Grarup S, Davies GJ, Wilson KS. Fungal GH25 muramidases: New family members with applications in animal nutrition and a crystal structure at 0.78Å resolution. Plos One. 16: e0248190. PMID 33711051 DOI: 10.1371/journal.pone.0248190 |
0.329 |
|
2021 |
McGregor NGS, Coines J, Borlandelli V, Amaki S, Artola M, Nin-Hill A, Linzel D, Yamada C, Arakawa T, Ishiwata A, Ito Y, van der Marel GA, Codée JDC, Fushinobu S, Overkleeft HS, ... ... Davies GJ, et al. Cysteine Nucleophiles in Glycosidase Catalysis: Application of a Covalent β-l-Arabinofuranosidase Inhibitor. Angewandte Chemie (International Ed. in English). PMID 33528085 DOI: 10.1002/anie.202013920 |
0.363 |
|
2020 |
Wu L, Wimmer N, Davies GJ, Ferro V. Structural insights into heparanase activity using a fluorogenic heparan sulfate disaccharide. Chemical Communications (Cambridge, England). PMID 33073275 DOI: 10.1039/d0cc05932c |
0.355 |
|
2020 |
Weber P, Thonhofer M, Averill S, Davies GJ, Santana AG, Müller P, Nasseri SA, Offen WA, Pabst BM, Paschke E, Schalli M, Torvisco A, Tschernutter M, Tysoe C, Windischhofer W, et al. Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and -5a-Substituted Derivatives of 4--Isofagomine. Molecules (Basel, Switzerland). 25. PMID 32899288 DOI: 10.3390/Molecules25174025 |
0.343 |
|
2020 |
Courtade G, Ciano L, Paradisi A, Lindley PJ, Forsberg Z, Sørlie M, Wimmer R, Davies GJ, Eijsink VGH, Walton PH, Aachmann FL. Mechanistic basis of substrate-O coupling within a chitin-active lytic polysaccharide monooxygenase: An integrated NMR/EPR study. Proceedings of the National Academy of Sciences of the United States of America. PMID 32723819 DOI: 10.1073/Pnas.2004277117 |
0.801 |
|
2020 |
Keenan T, Parmeggiani F, Malassis J, Fontenelle CQ, Vendeville JB, Offen W, Both P, Huang K, Marchesi A, Heyam A, Young C, Charnock SJ, Davies GJ, Linclau B, Flitsch SL, et al. Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-fluorinated Monosaccharides. Cell Chemical Biology. PMID 32619452 DOI: 10.1016/J.Chembiol.2020.06.005 |
0.72 |
|
2020 |
Armstrong Z, Kuo CL, Lahav D, Liu B, Johnson R, Beenakker TJM, de Boer C, Wong CS, van Rijssel ER, Debets MF, Florea BI, Hissink C, Boot RG, Geurink PP, Ovaa H, ... ... Davies GJ, et al. Manno-epi-cyclophellitols Enable Activity-Based Protein Profiling of Human α-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors. Journal of the American Chemical Society. PMID 32605368 DOI: 10.1021/Jacs.0C03880 |
0.368 |
|
2020 |
Rowland RJ, Wu L, Liu F, Davies GJ. A baculoviral system for the production of human β-glucocerebrosidase enables atomic resolution analysis. Acta Crystallographica. Section D, Structural Biology. 76: 565-580. PMID 32496218 DOI: 10.1107/S205979832000501X |
0.423 |
|
2020 |
Sobala LF, Speciale G, Zhu S, Raich L, Sannikova N, Thompson AJ, Hakki Z, Lu D, Shamsi Kazem Abadi S, Lewis AR, Rojas-Cervellera V, Bernardo-Seisdedos G, Zhang Y, Millet O, Jiménez-Barbero J, ... ... Davies GJ, et al. An Epoxide Intermediate in Glycosidase Catalysis. Acs Central Science. 6: 760-770. PMID 32490192 DOI: 10.1021/Acscentsci.0C00111 |
0.411 |
|
2020 |
Li J, Epa R, Scott NE, Skoneczny D, Sharma M, Snow AJD, Lingford JP, Goddard-Borger ED, Davies GJ, McConville MJ, Williams SJ. A sulfoglycolytic Entner-Doudoroff pathway in bv. SRDI565. Applied and Environmental Microbiology. PMID 32444469 DOI: 10.1128/Aem.00750-20 |
0.334 |
|
2020 |
Wu L, Davies GJ. An Overview of the Structure, Mechanism and Specificity of Human Heparanase. Advances in Experimental Medicine and Biology. 1221: 139-167. PMID 32274709 DOI: 10.1007/978-3-030-34521-1_5 |
0.472 |
|
2020 |
Ciano L, Paradisi A, Hemsworth GR, Tovborg M, Davies GJ, Walton PH. Insights from semi-oriented EPR spectroscopy studies into the interaction of lytic polysaccharide monooxygenases with cellulose. Dalton Transactions (Cambridge, England : 2003). PMID 32125319 DOI: 10.1039/C9Dt04065J |
0.796 |
|
2020 |
Deen MC, Proceviat C, Shan X, Wu L, Shen DL, Davies GJ, Vocadlo DJ. Selective fluorogenic β-glucocerebrosidase substrates for convenient analysis of enzyme activity in cell and tissue homogenates. Acs Chemical Biology. PMID 32109051 DOI: 10.1021/Acschembio.9B01044 |
0.382 |
|
2020 |
Vocadlo DJ, Alteen MG, Gros C, Meek R, Cardoso DA, Busmann J, Sangouard G, Deen MC, Tan HY, Shen DL, Russell CC, Davies GJ, Robinson PJ, McCluskey A. A direct fluorescent activity assay for glycosyltransferases enables convenient high-throughput screening: Application to O-GlcNAc Transferase. Angewandte Chemie (International Ed. in English). PMID 32092778 DOI: 10.1002/Anie.202000621 |
0.361 |
|
2020 |
McGregor N, Artola M, Nin-Hill A, Linzel D, Haon M, Reijngoud J, Ram AFJ, Rosso MN, van der Marel GA, Codée JDC, van Wezel GP, Berrin JG, Rovira C, Overkleeft HS, Davies GJ. Rational Design of Mechanism-Based Inhibitors and Activity-Based Probes for the Identification of Retaining α-L-Arabinofuranosidases. Journal of the American Chemical Society. PMID 32053363 DOI: 10.1021/Jacs.9B11351 |
0.34 |
|
2020 |
Mathieu Y, Offen WA, Forget SM, Ciano L, Viborg AH, Blagova E, Henrissat B, Walton PH, Davies GJ, Brumer H. Discovery of a Fungal Copper Radical Oxidase with High Catalytic Efficiency toward 5-Hydroxymethylfurfural and Benzyl Alcohols for Bioprocessing Acs Catalysis. 10: 3042-3058. DOI: 10.1021/Acscatal.9B04727 |
0.777 |
|
2020 |
Sharma M, Abayakoon P, Lingford JP, Epa R, John A, Jin Y, Goddard-Borger ED, Davies GJ, Williams SJ. Dynamic Structural Changes Accompany the Production of Dihydroxypropanesulfonate by Sulfolactaldehyde Reductase Acs Catalysis. 10: 2826-2836. DOI: 10.1021/Acscatal.9B04427 |
0.581 |
|
2020 |
Darby JF, Gilio AK, Piniello B, Roth C, Blagova E, Hubbard RE, Rovira C, Davies GJ, Wu L. Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V Acs Catalysis. 10: 8590-8596. DOI: 10.1021/Acscatal.0C02222 |
0.357 |
|
2019 |
Rovira C, Males A, Davies GJ, Williams SJ. Mannosidase mechanism: at the intersection of conformation and catalysis. Current Opinion in Structural Biology. 62: 79-92. PMID 31891872 DOI: 10.1016/J.Sbi.2019.11.008 |
0.408 |
|
2019 |
Armstrong Z, Davies GJ. Structure and function of Bs164 β-mannosidase from the founding member of glycoside hydrolase family GH164. The Journal of Biological Chemistry. PMID 31871050 DOI: 10.1074/Jbc.Ra119.011591 |
0.454 |
|
2019 |
Jariwala PB, Pellock SJ, Goldfarb D, Cloer EW, Artola M, Simpson JB, Bhatt AP, Walton WG, Roberts LR, Major MB, Davies GJ, Overkleeft HS, Redinbo MR. Discovering the Microbial Enzymes Driving Drug Toxicity with Activity-Based Protein Profiling. Acs Chemical Biology. PMID 31774274 DOI: 10.1021/Acschembio.9B00788 |
0.385 |
|
2019 |
Taylor EJ, Skjøt M, Skov LK, Klausen M, De Maria L, Gippert GP, Turkenburg JP, Davies GJ, Wilson KS. The C-Type Lysozyme from the upper Gastrointestinal Tract of the Stinkbird. International Journal of Molecular Sciences. 20. PMID 31698762 DOI: 10.3390/Ijms20225531 |
0.43 |
|
2019 |
Paradisi A, Johnston EM, Tovborg M, Nicoll C, Ciano L, Dowle A, McMaster J, Hancock Y, Davies GJ, Walton PH. Formation of a copper(II)-tyrosyl complex at the active site of lytic polysaccharide monooxygenases following oxidation by H2O2. Journal of the American Chemical Society. PMID 31675221 DOI: 10.1021/Jacs.9B09833 |
0.792 |
|
2019 |
King DT, Males A, Davies GJ, Vocadlo DJ. Molecular mechanisms regulating O-linked N-acetylglucosamine (O-GlcNAc)-processing enzymes. Current Opinion in Chemical Biology. 53: 131-144. PMID 31654859 DOI: 10.1016/J.Cbpa.2019.09.001 |
0.327 |
|
2019 |
Bule P, Chuzel L, Blagova E, Wu L, Gray MA, Henrissat B, Rapp E, Bertozzi CR, Taron CH, Davies GJ. Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action. Nature Communications. 10: 4816. PMID 31645552 DOI: 10.1038/S41467-019-12684-7 |
0.387 |
|
2019 |
Roth C, Moroz OV, Turkenburg JP, Blagova E, Waterman J, Ariza A, Ming L, Tianqi S, Andersen C, Davies GJ, Wilson KS. Structural and Functional Characterization of Three Novel Fungal Amylases with Enhanced Stability and pH Tolerance. International Journal of Molecular Sciences. 20. PMID 31623309 DOI: 10.3390/Ijms20194902 |
0.379 |
|
2019 |
Fowler CA, Sabbadin F, Ciano L, Hemsworth GR, Elias L, Bruce N, McQueen-Mason S, Davies GJ, Walton PH. Discovery, activity and characterisation of an AA10 lytic polysaccharide oxygenase from the shipworm symbiont . Biotechnology For Biofuels. 12: 232. PMID 31583018 DOI: 10.1186/S13068-019-1573-X |
0.811 |
|
2019 |
Sernee MF, Ralton JE, Nero TL, Sobala LF, Kloehn J, Vieira-Lara MA, Cobbold SA, Stanton L, Pires DEV, Hanssen E, Males A, Ward T, Bastidas LM, van der Peet PL, Parker MW, ... ... Davies GJ, et al. A Family of Dual-Activity Glycosyltransferase-Phosphorylases Mediates Mannogen Turnover and Virulence in Leishmania Parasites. Cell Host & Microbe. 26: 385-399.e9. PMID 31513773 DOI: 10.1016/J.Chom.2019.08.009 |
0.363 |
|
2019 |
Wu L, Armstrong Z, Schröder SP, de Boer C, Artola M, Aerts JM, Overkleeft HS, Davies GJ. An overview of activity-based probes for glycosidases. Current Opinion in Chemical Biology. 53: 25-36. PMID 31419756 DOI: 10.1016/J.Cbpa.2019.05.030 |
0.362 |
|
2019 |
Males A, Speciale G, Williams SJ, Davies GJ. Distortion of mannoimidazole supports a B boat transition state for the family GH125 α-1,6-mannosidase from Clostridium perfringens. Organic & Biomolecular Chemistry. PMID 31407758 DOI: 10.1039/C9Ob01161G |
0.374 |
|
2019 |
Schröder SP, de Boer C, McGregor NGS, Rowland RJ, Moroz O, Blagova E, Reijngoud J, Arentshorst M, Osborn D, Morant MD, Abbate E, Stringer MA, Krogh KBRM, Raich L, Rovira C, ... ... Davies GJ, et al. Dynamic and Functional Profiling of Xylan-Degrading Enzymes in Secretomes Using Activity-Based Probes. Acs Central Science. 5: 1067-1078. PMID 31263766 DOI: 10.1021/Acscentsci.9B00221 |
0.443 |
|
2019 |
von Freiesleben P, Moroz OV, Blagova E, Wiemann M, Spodsberg N, Agger JW, Davies GJ, Wilson KS, Stålbrand H, Meyer AS, Krogh KBRM. Crystal structure and substrate interactions of an unusual fungal non-CBM carrying GH26 endo-β-mannanase from Yunnania penicillata. Scientific Reports. 9: 2266. PMID 30783168 DOI: 10.1038/S41598-019-38602-X |
0.437 |
|
2019 |
Foley MH, Déjean G, Hemsworth GR, Davies GJ, Brumer H, Koropatkin NM. A Cell-Surface GH9 Endo-Glucanase Coordinates with Surface Glycan Binding Proteins to Mediate Xyloglucan Uptake in the Gut Symbiont Bacteroides ovatus. Journal of Molecular Biology. PMID 30668971 DOI: 10.1016/J.Jmb.2019.01.008 |
0.356 |
|
2019 |
Coyle T, Wu L, Debowski A, Davies G, Stubbs KA. Synthetic and crystallographic insight into exploiting sp2-hybridization in the development of α-L-fucosidase inhibitors. Chembiochem : a European Journal of Chemical Biology. PMID 30663832 DOI: 10.1002/Cbic.201800710 |
0.33 |
|
2019 |
Schroder SP, Boer C, McGregor NGS, Rowland RJ, Moroz O, Blagova E, Reijngoud J, Rovira C, Wezel GPv, Ram AFJ, Florea BI, Marel GAvd, Codee JDC, Wilson KS, Wu L, ... Davies GJ, et al. Dynamic and Functional Profiling of Xylan-Degrading Enzymes in Aspergillus Secretomes Using Activity-Based Probes Acs Nano. DOI: 10.2210/Pdb6Q8M/Pdb |
0.395 |
|
2019 |
Cabry MP, Offen WA, Winzer TH, Li Y, Graham IA, Davies GJ, Saleh P. Structure of Papaver somniferum O-Methyltransferase 1 Reveals Initiation of Noscapine Biosynthesis with Implications for Plant Natural Product Methylation Acs Catalysis. 9: 3840-3848. DOI: 10.2210/Pdb6I6M/Pdb |
0.346 |
|
2018 |
Budhadev D, Saxby K, Walton J, Davies G, Tyler PC, Schwörer R, Fascione MA. Using automated glycan assembly (AGA) for the practical synthesis of heparan sulfate oligosaccharide precursors. Organic & Biomolecular Chemistry. PMID 30543331 DOI: 10.1039/C8Ob02756K |
0.655 |
|
2018 |
Hemsworth GR, Ciano L, Davies GJ, Walton PH. Production and spectroscopic characterization of lytic polysaccharide monooxygenases. Methods in Enzymology. 613: 63-90. PMID 30509474 DOI: 10.1016/Bs.Mie.2018.10.014 |
0.822 |
|
2018 |
Lu D, Zhu S, Sobala LF, Bernardo-Seisdedos G, Millet O, Zhang Y, Jiménez-Barbero J, Davies GJ, Sollogoub M. From 1,4-Disaccharide to 1,3-Glycosyl Carbasugar: Synthesis of a Bespoke Inhibitor of Family GH99 Endo-α-mannosidase. Organic Letters. PMID 30427198 DOI: 10.1021/Acs.Orglett.8B03260 |
0.409 |
|
2018 |
Yang M, Fehl C, Lees KV, Lim EK, Offen WA, Davies GJ, Bowles DJ, Davidson MG, Roberts SJ, Davis BG. Functional and informatics analysis enables glycosyltransferase activity prediction. Nature Chemical Biology. PMID 30420693 DOI: 10.1038/S41589-018-0154-9 |
0.372 |
|
2018 |
Jain N, Attia MA, Offen WA, Davies GJ, Brumer H. Synthesis and application of a highly branched, mechanism-based 2-deoxy-2-fluoro-oligosaccharide inhibitor of endo-xyloglucanases. Organic & Biomolecular Chemistry. PMID 30387796 DOI: 10.1039/C8Ob02250J |
0.407 |
|
2018 |
Fowler CA, Hemsworth GR, Cuskin F, Hart S, Turkenburg J, Gilbert HJ, Walton PH, Davies GJ. Structure and function of a glycoside hydrolase family 8 endoxylanase from Teredinibacter turnerae. Acta Crystallographica. Section D, Structural Biology. 74: 946-955. PMID 30289404 DOI: 10.1107/S2059798318009737 |
0.652 |
|
2018 |
Abayakoon P, Jin Y, Lingford JP, Petricevic M, John A, Ryan E, Wai-Ying Mui J, Pires DEV, Ascher DB, Davies GJ, Goddard-Borger ED, Williams SJ. Structural and Biochemical Insights into the Function and Evolution of Sulfoquinovosidases. Acs Central Science. 4: 1266-1273. PMID 30276262 DOI: 10.1021/Acscentsci.8B00453 |
0.536 |
|
2018 |
Wu L, Davies GJ. Structure of the GH9 glucosidase/glucosaminidase from Vibrio cholerae. Acta Crystallographica. Section F, Structural Biology Communications. 74: 512-523. PMID 30084401 DOI: 10.1107/S2053230X18011019 |
0.449 |
|
2018 |
Urresti S, Cartmell A, Liu F, Walton PH, Davies GJ. Structural studies of the unusual metal-ion site of the GH124 endoglucanase from Ruminiclostridium thermocellum. Acta Crystallographica. Section F, Structural Biology Communications. 74: 496-505. PMID 30084399 DOI: 10.1107/S2053230X18006842 |
0.61 |
|
2018 |
Moroz OV, Sobala LF, Blagova E, Coyle T, Peng W, Mørkeberg Krogh KBR, Stubbs KA, Wilson KS, Davies GJ. Structure of a Talaromyces pinophilus GH62 arabinofuranosidase in complex with AraDNJ at 1.25 Å resolution. Acta Crystallographica. Section F, Structural Biology Communications. 74: 490-495. PMID 30084398 DOI: 10.1107/S2053230X18000250 |
0.455 |
|
2018 |
Schröder SP, Kallemeijn WW, Debets MF, Sobala LF, Hakki Z, Williams SJ, Beenakker TJM, Aerts JMFG, van der Marel GA, Codée JDC, Davies GJ, Overkleeft HS. Spiro-epoxyglycosides as activity-based probes for glycoside hydrolase family 99 endomannosidase/endomannanase. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29797675 DOI: 10.1002/Chem.201801902 |
0.502 |
|
2018 |
Roth C, Moroz OV, Ariza A, Skov LK, Ayabe K, Davies GJ, Wilson KS. Structural insight into industrially relevant glucoamylases: flexible positions of starch-binding domains. Acta Crystallographica. Section D, Structural Biology. 74: 463-470. PMID 29717717 DOI: 10.1107/S2059798318004989 |
0.391 |
|
2018 |
Thompson AJ, Spears RJ, Zhu Y, Suits MDL, Williams SJ, Gilbert HJ, Davies GJ. Bacteroides thetaiotaomicron generates diverse α-mannosidase activities through subtle evolution of a distal substrate-binding motif. Acta Crystallographica. Section D, Structural Biology. 74: 394-404. PMID 29717710 DOI: 10.1107/S2059798318002942 |
0.491 |
|
2018 |
Schröder SP, Wu L, Artola M, Hansen T, Offen WA, Ferraz MJ, Li KY, Aerts JMFG, van der Marel GA, Codée JDC, Davies GJ, Overkleeft HS. Gluco-1H-imidazole: a new class of azole-type β-glucosidase inhibitor. Journal of the American Chemical Society. PMID 29601200 DOI: 10.1021/Jacs.8B02399 |
0.351 |
|
2018 |
Abayakoon P, Lingford JP, Jin Y, Bengt C, Davies GJ, Yao S, Goddard-Borger ED, Williams SJ. Discovery and characterization of a sulfoquinovose mutarotase using kinetic analysis at equilibrium by exchange spectroscopy. The Biochemical Journal. PMID 29535276 DOI: 10.1042/Bcj20170947 |
0.469 |
|
2018 |
Fernandes PZ, Petricevic M, Sobala L, Davies GJ, Williams SJ. Exploration of strategies for mechanism-based inhibitor design for family GH99 endo-α-1,2-mannanases. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29508463 DOI: 10.1002/Chem.201800435 |
0.385 |
|
2018 |
Sabbadin F, Hemsworth GR, Ciano L, Henrissat B, Dupree P, Tryfona T, Marques RDS, Sweeney ST, Besser K, Elias L, Pesante G, Li Y, Dowle AA, Bates R, Gomez LD, ... ... Davies GJ, et al. An ancient family of lytic polysaccharide monooxygenases with roles in arthropod development and biomass digestion. Nature Communications. 9: 756. PMID 29472725 DOI: 10.1038/S41467-018-03142-X |
0.789 |
|
2018 |
Attia MA, Nelson CE, Offen WA, Jain N, Davies GJ, Gardner JG, Brumer H. In vitro and in vivo characterization of threeglycoside hydrolase family 5 members reveals potent xyloglucan backbone-cleaving functions. Biotechnology For Biofuels. 11: 45. PMID 29467823 DOI: 10.1186/S13068-018-1039-6 |
0.423 |
|
2018 |
Couturier M, Ladevèze S, Sulzenbacher G, Ciano L, Fanuel M, Moreau C, Villares A, Cathala B, Chaspoul F, Frandsen KE, Labourel A, Herpoël-Gimbert I, Grisel S, Haon M, Lenfant N, ... ... Davies GJ, et al. Lytic xylan oxidases from wood-decay fungi unlock biomass degradation. Nature Chemical Biology. PMID 29377002 DOI: 10.1038/Nchembio.2558 |
0.805 |
|
2018 |
Abbott W, Alber O, Bayer E, Berrin J, Boraston A, Brumer H, Brzezinski R, Clarke A, Cobucci-Ponzano B, Cockburn D, Coutinho P, Czjzek M, Dassa B, Davies GJ, Eijsink V, et al. Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes Glycobiology. 28: 3-8. PMID 29040563 DOI: 10.1093/Glycob/Cwx089 |
0.441 |
|
2018 |
Moroz OV, Jensen PF, McDonald SP, McGregor N, Blagova E, Comamala G, Segura DR, Anderson L, Vasu SM, Rao VP, Giger L, Monrad RN, Svendsen A, Nielsen JE, Henrissat B, ... Davies GJ, et al. Structural Dynamics and Catalytic Properties of a Multimodular Xanthanase Acs Catalysis. 8: 6021-6034. DOI: 10.2210/Pdb6Fhj/Pdb |
0.458 |
|
2018 |
Ciano L, Davies GJ, Tolman WB, Walton PH. Bracing copper for the catalytic oxidation of C–H bonds Nature Catalysis. 1: 571-577. DOI: 10.1038/s41929-018-0110-9 |
0.548 |
|
2018 |
Wang B, Johnston EM, Li P, Shaik S, Davies GJ, Walton PH, Rovira C. QM/MM Studies into the H2O2-Dependent Activity of Lytic Polysaccharide Monooxygenases: Evidence for the Formation of a Caged Hydroxyl Radical Intermediate Acs Catalysis. 8: 1346-1351. DOI: 10.1021/Acscatal.7B03888 |
0.641 |
|
2017 |
Darby JF, Atobe M, Firth JD, Bond P, Davies GJ, O'Brien P, Hubbard RE. Increase of enzyme activity through specific covalent modification with fragments. Chemical Science. 8: 7772-7779. PMID 29163914 DOI: 10.1039/C7Sc01966A |
0.471 |
|
2017 |
Schröder SP, van de Sande JW, Kallemeijn WW, Kuo CL, Artola M, van Rooden EJ, Jiang J, Beenakker TJM, Florea BI, Offen WA, Davies GJ, Minnaard AJ, Aerts JMFG, Codée JDC, van der Marel GA, et al. Towards broad spectrum activity-based glycosidase probes: synthesis and evaluation of deoxygenated cyclophellitol aziridines. Chemical Communications (Cambridge, England). PMID 29116266 DOI: 10.1039/C7Cc07730K |
0.328 |
|
2017 |
Tamura K, Hemsworth GR, Déjean G, Rogers TE, Pudlo NA, Urs K, Jain N, Davies GJ, Martens EC, Brumer H. Molecular Mechanism by which Prominent Human Gut Bacteroidetes Utilize Mixed-Linkage Beta-Glucans, Major Health-Promoting Cereal Polysaccharides. Cell Reports. 21: 417-430. PMID 29020628 DOI: 10.1016/J.Celrep.2017.09.049 |
0.331 |
|
2017 |
Lahav D, Liu B, van den Berg RJBHN, van den Nieuwendijk AMCH, Wennekes T, Ghisaidoobe AT, Breen I, Ferraz MJ, Kuo CL, Wu L, Geurink PP, Ovaa H, van der Marel GA, van der Stelt M, Boot RG, ... Davies GJ, et al. A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Non-lysosomal Glucosylceramidase. Journal of the American Chemical Society. PMID 28937220 DOI: 10.1021/Jacs.7B07352 |
0.373 |
|
2017 |
Artola M, Wu L, Ferraz MJ, Kuo CL, Raich L, Breen IZ, Offen WA, Codée JDC, van der Marel GA, Rovira C, Aerts JMFG, Davies GJ, Overkleeft HS. 1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor. Acs Central Science. 3: 784-793. PMID 28776021 DOI: 10.1021/Acscentsci.7B00214 |
0.36 |
|
2017 |
Belz T, Jin Y, Coines J, Rovira C, Davies GJ, Williams SJ. An atypical interaction explains the high-affinity of a non-hydrolyzable S-linked 1,6-α-mannanase inhibitor. Chemical Communications (Cambridge, England). PMID 28766587 DOI: 10.1039/C7Cc04977C |
0.463 |
|
2017 |
Wu L, Jiang J, Jin Y, Kallemeijn WW, Kuo CL, Artola M, Dai W, van Elk C, van Eijk M, van der Marel GA, Codée JDC, Florea BI, Aerts JMFG, Overkleeft HS, Davies GJ. Activity-based probes for functional interrogation of retaining β-glucuronidases. Nature Chemical Biology. PMID 28581485 DOI: 10.1038/Nchembio.2395 |
0.518 |
|
2017 |
Males A, Raich L, Williams SJ, Rovira C, Davies GJ. Conformational analysis of the mannosidase inhibitor kifunensine: a quantum mechanical and structural approach. Chembiochem : a European Journal of Chemical Biology. PMID 28493500 DOI: 10.1002/Cbic.201700166 |
0.43 |
|
2017 |
Beenakker TJM, Wander D, Offen WA, Artola M, Raich L, Ferraz MJ, Li KY, Houben JHPM, van Rijssel ER, Hansen T, van der Marel GA, Codée JDC, Aerts JMFG, Rovira C, Davies GJ, et al. Carba-Cyclophellitols are Neutral Retaining Glucosidase Inhibitors. Journal of the American Chemical Society. PMID 28463498 DOI: 10.1021/Jacs.7B01773 |
0.345 |
|
2017 |
Roth C, Chan S, Offen WA, Hemsworth GR, Willems LI, King DT, Varghese V, Britton R, Vocadlo DJ, Davies GJ. Structural and functional insight into human O-GlcNAcase. Nature Chemical Biology. PMID 28346405 DOI: 10.1038/nchembio.2358 |
0.342 |
|
2017 |
Ndeh D, Rogowski A, Cartmell A, Luis AS, Baslé A, Gray J, Venditto I, Briggs J, Zhang X, Labourel A, Terrapon N, Buffetto F, Nepogodiev S, Xiao Y, Field RA, ... ... Davies GJ, et al. Complex pectin metabolism by gut bacteria reveals novel catalytic functions. Nature. PMID 28329766 DOI: 10.1038/Nature21725 |
0.417 |
|
2016 |
Cekic N, Heinonen JE, Stubbs KA, Roth C, He Y, Bennet AJ, McEachern EJ, Davies GJ, Vocadlo DJ. Analysis of transition state mimicry by tight binding aminothiazoline inhibitors provides insight into catalysis by human -GlcNAcase. Chemical Science. 7: 3742-3750. PMID 29997861 DOI: 10.1039/C6Sc00370B |
0.39 |
|
2016 |
Jin Y, Petricevic M, John A, Raich L, Jenkins H, Portela De Souza L, Cuskin F, Gilbert HJ, Rovira C, Goddard-Borger ED, Williams SJ, Davies GJ. A β-Mannanase with a Lysozyme-like Fold and a Novel Molecular Catalytic Mechanism. Acs Central Science. 2: 896-903. PMID 28058278 DOI: 10.1021/Acscentsci.6B00232 |
0.52 |
|
2016 |
Alonso-Gil S, Males A, Fernandes P, Williams SJ, Davies GJ, Rovira C. Computational design-of-experiment unveils the conformational reaction coordinate of GH125 α-mannosidases. Journal of the American Chemical Society. PMID 28026180 DOI: 10.1021/Jacs.6B11247 |
0.452 |
|
2016 |
Petricevic M, Sobala LF, Fernandes P, Raich L, Thompson AJ, Bernardo-Seisdedos G, Millet O, Zhu S, Sollogoub M, Jimenez-Barbero J, Rovira C, Davies GJ, Williams SJ. Contribution of shape and charge to the inhibition of a family GH99 endo-α-1,2-mannanase. Journal of the American Chemical Society. PMID 27992199 DOI: 10.1021/Jacs.6B10075 |
0.431 |
|
2016 |
Agirre J, Davies GJ, Wilson KS, Cowtan KD. Carbohydrate structure: the rocky road to automation. Current Opinion in Structural Biology. 44: 39-47. PMID 27940408 DOI: 10.1016/J.Sbi.2016.11.011 |
0.328 |
|
2016 |
Gregory RC, Hemsworth GR, Turkenburg JP, Hart SJ, Walton PH, Davies GJ. Activity, stability and 3-D structure of the Cu(ii) form of a chitin-active lytic polysaccharide monooxygenase from Bacillus amyloliquefaciens. Dalton Transactions (Cambridge, England : 2003). PMID 27722375 DOI: 10.1039/C6Dt02793H |
0.682 |
|
2016 |
Roth C, Petricevic M, John A, Goddard-Borger ED, Davies GJ, Williams SJ. Structural and mechanistic insights into a Bacteroides vulgatus retaining N-acetyl-β-galactosaminidase that uses neighbouring group participation. Chemical Communications (Cambridge, England). PMID 27546776 DOI: 10.1039/C6Cc04649E |
0.397 |
|
2016 |
Hemsworth GR, Thompson AJ, Stepper J, Sobala ŁF, Coyle T, Larsbrink J, Spadiut O, Goddard-Borger ED, Stubbs KA, Brumer H, Davies GJ. Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut. Open Biology. 6. PMID 27466444 DOI: 10.1098/Rsob.160142 |
0.465 |
|
2016 |
Jiang J, Kuo CL, Wu L, Franke C, Kallemeijn WW, Florea BI, van Meel E, van der Marel GA, Codée JD, Boot RG, Davies GJ, Overkleeft HS, Aerts JM. Detection of Active Mammalian GH31 α-Glucosidases in Health and Disease Using In-Class, Broad-Spectrum Activity-Based Probes. Acs Central Science. 2: 351-8. PMID 27280170 DOI: 10.1021/Acscentsci.6B00057 |
0.314 |
|
2016 |
Hottin A, Wright DW, Moreno-Clavijo E, Moreno-Vargas AJ, Davies GJ, Behr JB. Exploring the divalent effect in fucosidase inhibition with stereoisomeric pyrrolidine dimers. Organic & Biomolecular Chemistry. PMID 27138139 DOI: 10.1039/C6Ob00647G |
0.342 |
|
2016 |
Charoenwattanasatien R, Pengthaisong S, Breen I, Mutoh R, Sansenya S, Hua Y, Tankrathok A, Wu L, Songsiriritthigul C, Tanaka H, Williams SJ, Davies GJ, Kurisu G, Ketudat Cairns JR. Bacterial β-glucosidase reveals the structural and functional basis of genetic defects in human glucocerebrosidase 2 (GBA2). Acs Chemical Biology. PMID 27115290 DOI: 10.1021/Acschembio.6B00192 |
0.402 |
|
2016 |
Walton PH, Davies GJ. On the catalytic mechanisms of lytic polysaccharide monooxygenases. Current Opinion in Chemical Biology. PMID 27094791 DOI: 10.1016/J.Cbpa.2016.04.001 |
0.667 |
|
2016 |
Attia M, Stepper J, Davies GJ, Brumer H. Functional and structural characterization of a potent GH74 endo-xyloglucanase from the soil saprophyte Cellvibrio japonicus unravels the first step of xyloglucan degradation. The Febs Journal. 283: 1701-19. PMID 26929175 DOI: 10.1111/Febs.13696 |
0.453 |
|
2016 |
Frandsen KE, Simmons TJ, Dupree P, Poulsen JN, Hemsworth GR, Ciano L, Johnston EM, Tovborg M, Johansen KS, von Freiesleben P, Marmuse L, Fort S, Cottaz S, Driguez H, Henrissat B, ... ... Davies GJ, et al. The molecular basis of polysaccharide cleavage by lytic polysaccharide monooxygenases. Nature Chemical Biology. PMID 26928935 DOI: 10.1038/Nchembio.2029 |
0.824 |
|
2016 |
Hottin A, Scandolera A, Duca L, Wright DW, Davies GJ, Behr JB. A second-generation ferrocene-iminosugar hybrid with improved fucosidase binding properties. Bioorganic & Medicinal Chemistry Letters. PMID 26897594 DOI: 10.1016/J.Bmcl.2016.02.017 |
0.389 |
|
2016 |
Agirre J, Ariza A, Offen WA, Turkenburg JP, Roberts SM, McNicholas S, Harris PV, McBrayer B, Dohnalek J, Cowtan KD, Davies GJ, Wilson KS. Three-dimensional structures of two heavily N-glycosylated Aspergillus sp. family GH3 β-D-glucosidases. Acta Crystallographica. Section D, Structural Biology. 72: 254-265. PMID 26894673 DOI: 10.1107/S2059798315024237 |
0.446 |
|
2016 |
Speciale G, Jin Y, Davies GJ, Williams SJ, Goddard-Borger ED. YihQ is a sulfoquinovosidase that cleaves sulfoquinovosyl diacylglyceride sulfolipids. Nature Chemical Biology. PMID 26878550 DOI: 10.1038/Nchembio.2023 |
0.519 |
|
2016 |
Hemsworth GR, Déjean G, Davies GJ, Brumer H. Learning from microbial strategies for polysaccharide degradation. Biochemical Society Transactions. 44: 94-108. PMID 26862194 DOI: 10.1042/Bst20150180 |
0.311 |
|
2016 |
Davies GJ, Williams SJ. Carbohydrate-active enzymes: sequences, shapes, contortions and cells. Biochemical Society Transactions. 44: 79-87. PMID 26862192 DOI: 10.1042/Bst20150186 |
0.468 |
|
2016 |
Thompson AJ, Speciale G, Iglesias-Fernández J, Hakki Z, Belz T, Cartmell A, Spears RJ, Chandler E, Temple MJ, Stepper J, Gilbert HJ, Rovira C, Williams SJ, Davies GJ. Corrigendum: Evidence for a Boat Conformation at the Transition State of GH76 α-1,6-Mannanases-Key Enzymes in Bacterial and Fungal Mannoprotein Metabolism. Angewandte Chemie (International Ed. in English). 55: 1949. PMID 26836331 DOI: 10.1002/Anie.201511540 |
0.426 |
|
2016 |
Crouch LI, Labourel A, Walton PH, Davies GJ, Gilbert HJ. The contribution of non-catalytic carbohydrate binding modules to the activity lytic polysaccharide monooxygenases. The Journal of Biological Chemistry. PMID 26801613 DOI: 10.1074/Jbc.M115.702365 |
0.699 |
|
2016 |
Kwan DH, Jin Y, Jiang J, Chen HM, Kötzler MP, Overkleeft HS, Davies G, Withers SG. Chemoenzymatic synthesis of 6-phospho-cyclophellitol as a novel probe of 6-phospho-β-glucosidases. Febs Letters. PMID 26790390 DOI: 10.1002/1873-3468.12059 |
0.582 |
|
2016 |
Wu L, Viola CM, Brzozowski AM, Davies GJ. Corrigendum: Structural characterization of human heparanase reveals insights into substrate recognition. Nature Structural & Molecular Biology. 23: 91. PMID 26733221 DOI: 10.1038/Nsmb0116-91 |
0.37 |
|
2016 |
Urresti S, Yin DT, Lafond M, Johnston EM, Derikvand F, Ciano L, Berrin J, Henrissat B, Walton PH, Brumer H, Davies GJ. Structure-function characterization reveals catalytic diversity in the galactose oxidase family Acta Crystallographica Section a Foundations and Advances. 72: s33-s34. DOI: 10.1107/S2053273316099472 |
0.796 |
|
2015 |
Yin DT, Urresti S, Lafond M, Johnston EM, Derikvand F, Ciano L, Berrin JG, Henrissat B, Walton PH, Davies GJ, Brumer H. Structure-function characterization reveals new catalytic diversity in the galactose oxidase and glyoxal oxidase family. Nature Communications. 6: 10197. PMID 26680532 DOI: 10.1038/Ncomms10197 |
0.814 |
|
2015 |
Wu L, Viola CM, Brzozowski AM, Davies GJ. Structural characterization of human heparanase reveals insights into substrate recognition. Nature Structural & Molecular Biology. PMID 26575439 DOI: 10.1038/Nsmb.3136 |
0.457 |
|
2015 |
Bergeron-Brlek M, Goodwin-Tindall J, Cekic N, Roth C, Zandberg WF, Shan X, Varghese V, Chan S, Davies GJ, Vocadlo DJ, Britton R. A Convenient Approach to Stereoisomeric Iminocyclitols: Generation of Potent Brain-Permeable OGA Inhibitors. Angewandte Chemie (International Ed. in English). PMID 26545827 DOI: 10.1002/Anie.201507985 |
0.347 |
|
2015 |
Hemsworth GR, Johnston EM, Davies GJ, Walton PH. Lytic Polysaccharide Monooxygenases in Biomass Conversion. Trends in Biotechnology. PMID 26472212 DOI: 10.1016/J.Tibtech.2015.09.006 |
0.651 |
|
2015 |
Cuskin F, Baslé A, Ladevèze S, Day AM, Gilbert HJ, Davies GJ, Potocki-Véronèse G, Lowe EC. The GH130 Family of Mannoside Phosphorylases Contains Glycoside Hydrolases That Target β-1,2-Mannosidic Linkages in Candida Mannan. The Journal of Biological Chemistry. 290: 25023-33. PMID 26286752 DOI: 10.1074/Jbc.M115.681460 |
0.436 |
|
2015 |
Aalbers F, Turkenburg JP, Davies GJ, Dijkhuizen L, Lammerts van Bueren A. Structural and Functional Characterization of a Novel Family GH115 4-O-Methyl-α-Glucuronidase with Specificity for Decorated Arabinogalactans. Journal of Molecular Biology. PMID 26186997 DOI: 10.1016/J.Jmb.2015.07.006 |
0.427 |
|
2015 |
Thompson AJ, Speciale G, Iglesias-Fernández J, Hakki Z, Belz T, Cartmell A, Spears RJ, Chandler E, Temple MJ, Stepper J, Gilbert HJ, Rovira C, Williams SJ, Davies GJ. Evidence for a boat conformation at the transition state of GH76 α-1,6-mannanases--key enzymes in bacterial and fungal mannoprotein metabolism. Angewandte Chemie (International Ed. in English). 54: 5378-82. PMID 25772148 DOI: 10.1002/Anie.201410502 |
0.43 |
|
2015 |
Thompson AJ, Cuskin F, Spears RJ, Dabin J, Turkenburg JP, Gilbert HJ, Davies GJ. Structure of the GH76 α-mannanase homolog, BT2949, from the gut symbiont Bacteroides thetaiotaomicron. Acta Crystallographica. Section D, Biological Crystallography. 71: 408-15. PMID 25664752 DOI: 10.1107/S1399004714026443 |
0.411 |
|
2015 |
Moroz OV, Maranta M, Shaghasi T, Harris PV, Wilson KS, Davies GJ. The three-dimensional structure of the cellobiohydrolase Cel7A from Aspergillus fumigatus at 1.5 Å resolution. Acta Crystallographica. Section F, Structural Biology Communications. 71: 114-20. PMID 25615982 DOI: 10.1107/S2053230X14027307 |
0.459 |
|
2015 |
Offen WA, Viksoe-Nielsen A, Borchert TV, Wilson KS, Davies GJ. Three-dimensional structure of a variant `Termamyl-like' Geobacillus stearothermophilus α-amylase at 1.9 Å resolution. Acta Crystallographica. Section F, Structural Biology Communications. 71: 66-70. PMID 25615972 DOI: 10.1107/S2053230X14026508 |
0.328 |
|
2015 |
Lo Leggio L, Simmons TJ, Poulsen JC, Frandsen KE, Hemsworth GR, Stringer MA, von Freiesleben P, Tovborg M, Johansen KS, De Maria L, Harris PV, Soong CL, Dupree P, Tryfona T, Lenfant N, ... ... Davies GJ, et al. Structure and boosting activity of a starch-degrading lytic polysaccharide monooxygenase. Nature Communications. 6: 5961. PMID 25608804 DOI: 10.1038/Ncomms6961 |
0.723 |
|
2015 |
Cuskin F, Lowe EC, Temple MJ, Zhu Y, Cameron EA, Pudlo NA, Porter NT, Urs K, Thompson AJ, Cartmell A, Rogowski A, Hamilton BS, Chen R, Tolbert TJ, Piens K, ... ... Davies GJ, et al. Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism. Nature. 517: 165-9. PMID 25567280 DOI: 10.1038/Nature13995 |
0.31 |
|
2015 |
Hakki Z, Thompson AJ, Bellmaine S, Speciale G, Davies GJ, Williams SJ. Structural and kinetic dissection of the endo-α-1,2-mannanase activity of bacterial GH99 glycoside hydrolases from Bacteroides spp. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 1966-77. PMID 25487964 DOI: 10.1002/Chem.201405539 |
0.427 |
|
2015 |
Hottin A, Wright DW, Davies GJ, Behr JB. Exploiting the hydrophobic terrain in fucosidases with aryl-substituted pyrrolidine iminosugars. Chembiochem : a European Journal of Chemical Biology. 16: 277-83. PMID 25427942 DOI: 10.1002/Cbic.201402509 |
0.407 |
|
2015 |
Urresti S, Hemsworth GR, Screeton HC, Walton PH, Davies GJ. Structure and function of lytic polysaccharide monooxygenases Acta Crystallographica Section a Foundations and Advances. 71: s225-s225. DOI: 10.1107/S2053273315096618 |
0.598 |
|
2014 |
Darby JF, Landström J, Roth C, He Y, Davies GJ, Hubbard RE. Discovery of selective small-molecule activators of a bacterial glycoside hydrolase. Angewandte Chemie (International Ed. in English). 53: 13419-23. PMID 25291993 DOI: 10.1002/Anie.201407081 |
0.449 |
|
2014 |
Larsbrink J, Thompson AJ, Lundqvist M, Gardner JG, Davies GJ, Brumer H. A complex gene locus enables xyloglucan utilization in the model saprophyte Cellvibrio japonicus. Molecular Microbiology. 94: 418-33. PMID 25171165 DOI: 10.1111/Mmi.12776 |
0.405 |
|
2014 |
Speciale G, Thompson AJ, Davies GJ, Williams SJ. Dissecting conformational contributions to glycosidase catalysis and inhibition. Current Opinion in Structural Biology. 28: 1-13. PMID 25016573 DOI: 10.1016/J.Sbi.2014.06.003 |
0.398 |
|
2014 |
Kjaergaard CH, Qayyum MF, Wong SD, Xu F, Hemsworth GR, Walton DJ, Young NA, Davies GJ, Walton PH, Johansen KS, Hodgson KO, Hedman B, Solomon EI. Spectroscopic and computational insight into the activation of O2 by the mononuclear Cu center in polysaccharide monooxygenases. Proceedings of the National Academy of Sciences of the United States of America. 111: 8797-802. PMID 24889637 DOI: 10.1073/Pnas.1408115111 |
0.652 |
|
2014 |
Thi NN, Offen WA, Shareck F, Davies GJ, Doucet N. Structure and activity of the streptomyces coelicolor A3(2) β-N-acetylhexosaminidase provides further insight into GH20 family catalysis and inhibition Biochemistry. 53: 1789-1800. PMID 24559145 DOI: 10.1021/Bi401697J |
0.462 |
|
2014 |
Larsbrink J, Rogers TE, Hemsworth GR, McKee LS, Tauzin AS, Spadiut O, Klinter S, Pudlo NA, Urs K, Koropatkin NM, Creagh AL, Haynes CA, Kelly AG, Cederholm SN, Davies GJ, et al. A discrete genetic locus confers xyloglucan metabolism in select human gut Bacteroidetes. Nature. 506: 498-502. PMID 24463512 DOI: 10.1038/Nature12907 |
0.331 |
|
2014 |
He Y, Roth C, Turkenburg JP, Davies GJ. Three-dimensional structure of a Streptomyces sviceus GNAT acetyltransferase with similarity to the C-terminal domain of the human GH84 O-GlcNAcase. Acta Crystallographica. Section D, Biological Crystallography. 70: 186-95. PMID 24419391 DOI: 10.1107/S1399004713029155 |
0.375 |
|
2014 |
Kim RQ, Offen WA, Davies GJ, Stubbs KA. Structural enzymology of Helicobacter pylori methylthioadenosine nucleosidase in the futalosine pathway Acta Crystallographica Section D: Biological Crystallography. 70: 177-185. PMID 24419390 DOI: 10.1107/S1399004713026655 |
0.398 |
|
2014 |
Hemsworth GR, Henrissat B, Davies GJ, Walton PH. Discovery and characterization of a new family of lytic polysaccharide monooxygenases. Nature Chemical Biology. 10: 122-6. PMID 24362702 DOI: 10.1038/Nchembio.1417 |
0.7 |
|
2014 |
Williams RJ, Iglesias-Fernández J, Stepper J, Jackson A, Thompson AJ, Lowe EC, White JM, Gilbert HJ, Rovira C, Davies GJ, Williams SJ. Combined inhibitor free-energy landscape and structural analysis reports on the mannosidase conformational coordinate. Angewandte Chemie (International Ed. in English). 53: 1087-91. PMID 24339341 DOI: 10.1002/Anie.201308334 |
0.432 |
|
2013 |
Davies GJ, Henrissat B. Cracking the code, slowly: the state of carbohydrate-active enzymes in 2013. Current Opinion in Structural Biology. 23: 649-51. PMID 24076043 DOI: 10.1016/J.Sbi.2013.09.001 |
0.302 |
|
2013 |
Shaikh FA, Lammerts van Bueren A, Davies GJ, Withers SG. Identifying the catalytic acid/base in GH29 α-L-fucosidase subfamilies. Biochemistry. 52: 5857-64. PMID 23883131 DOI: 10.1021/Bi400183Q |
0.428 |
|
2013 |
Wright DW, Moreno-Vargas AJ, Carmona AT, Robina I, Davies GJ. Three dimensional structure of a bacterial α-l-fucosidase with a 5-membered iminocyclitol inhibitor. Bioorganic & Medicinal Chemistry. 21: 4751-4. PMID 23830696 DOI: 10.1016/J.Bmc.2013.05.056 |
0.416 |
|
2013 |
Hemsworth GR, Davies GJ, Walton PH. Recent insights into copper-containing lytic polysaccharide mono-oxygenases. Current Opinion in Structural Biology. 23: 660-8. PMID 23769965 DOI: 10.1016/J.Sbi.2013.05.006 |
0.693 |
|
2013 |
Hottin A, Wright DW, Steenackers A, Delannoy P, Dubar F, Biot C, Davies GJ, Behr JB. α-L-fucosidase inhibition by pyrrolidine-ferrocene hybrids: rationalization of ligand-binding properties by structural studies. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 9526-33. PMID 23740878 DOI: 10.1002/Chem.201301001 |
0.32 |
|
2013 |
Hemsworth GR, Taylor EJ, Kim RQ, Gregory RC, Lewis SJ, Turkenburg JP, Parkin A, Davies GJ, Walton PH. The copper active site of CBM33 polysaccharide oxygenases. Journal of the American Chemical Society. 135: 6069-77. PMID 23540833 DOI: 10.1021/Ja402106E |
0.652 |
|
2013 |
Stepper J, Dabin J, Eklof JM, Thongpoo P, Kongsaeree P, Taylor EJ, Turkenburg JP, Brumer H, Davies GJ. Structure and activity of the Streptococcus pyogenes family GH1 6-phospho-β-glucosidase SPy1599. Acta Crystallographica. Section D, Biological Crystallography. 69: 16-23. PMID 23275159 DOI: 10.1107/S0907444912041005 |
0.401 |
|
2013 |
Moreno-Clavijo E, Carmona AT, Moreno-Vargas AJ, Molina L, Wright DW, Davies GJ, Robina I. Exploring a multivalent approach to α-L-fucosidase inhibition European Journal of Organic Chemistry. 7328-7336. DOI: 10.1002/Ejoc.201300878 |
0.328 |
|
2012 |
Cuskin F, Flint JE, Gloster TM, Morland C, Baslé A, Henrissat B, Coutinho PM, Strazzulli A, Solovyova AS, Davies GJ, Gilbert HJ. How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity. Proceedings of the National Academy of Sciences of the United States of America. 109: 20889-94. PMID 23213210 DOI: 10.1073/Pnas.1212034109 |
0.484 |
|
2012 |
Hurtado-Guerrero R, Davies GJ. Recent structural and mechanistic insights into post-translational enzymatic glycosylation. Current Opinion in Chemical Biology. 16: 479-87. PMID 23142486 DOI: 10.1016/J.Cbpa.2012.10.013 |
0.396 |
|
2012 |
Larsbrink J, Izumi A, Hemsworth GR, Davies GJ, Brumer H. Structural enzymology of Cellvibrio japonicus Agd31B protein reveals α-transglucosylase activity in glycoside hydrolase family 31. The Journal of Biological Chemistry. 287: 43288-99. PMID 23132856 DOI: 10.1074/Jbc.M112.416511 |
0.438 |
|
2012 |
Withers SG, Davies GJ. Glycobiology: The case of the missing base. Nature Chemical Biology. 8: 952-3. PMID 23103941 DOI: 10.1038/Nchembio.1117 |
0.36 |
|
2012 |
Thompson AJ, Dabin J, Iglesias-Fernández J, Ardèvol A, Dinev Z, Williams SJ, Bande O, Siriwardena A, Moreland C, Hu TC, Smith DK, Gilbert HJ, Rovira C, Davies GJ. The reaction coordinate of a bacterial GH47 α-mannosidase: a combined quantum mechanical and structural approach. Angewandte Chemie (International Ed. in English). 51: 10997-1001. PMID 23012075 DOI: 10.1002/Anie.201205338 |
0.43 |
|
2012 |
Thompson AJ, Heu T, Shaghasi T, Benyamino R, Jones A, Friis EP, Wilson KS, Davies GJ. Structure of the catalytic core module of the Chaetomium thermophilum family GH6 cellobiohydrolase Cel6A. Acta Crystallographica. Section D, Biological Crystallography. 68: 875-82. PMID 22868752 DOI: 10.1107/S0907444912016496 |
0.495 |
|
2012 |
Wyszynski FJ, Lee SS, Yabe T, Wang H, Gomez-Escribano JP, Bibb MJ, Lee SJ, Davies GJ, Davis BG. Biosynthesis of the tunicamycin antibiotics proceeds via unique exo-glycal intermediates. Nature Chemistry. 4: 539-46. PMID 22717438 DOI: 10.1038/Nchem.1351 |
0.371 |
|
2012 |
Macauley MS, Chan J, Zandberg WF, He Y, Whitworth GE, Stubbs KA, Yuzwa SA, Bennet AJ, Varki A, Davies GJ, Vocadlo DJ. Metabolism of vertebrate amino sugars with N-glycolyl groups: intracellular β-O-linked N-glycolylglucosamine (GlcNGc), UDP-GlcNGc, and the biochemical and structural rationale for the substrate tolerance of β-O-linked β-N-acetylglucosaminidase. The Journal of Biological Chemistry. 287: 28882-97. PMID 22692202 DOI: 10.1074/Jbc.M112.363721 |
0.366 |
|
2012 |
Roberts SM, Davies GJ. The crystallization and structural analysis of cellulases (and other glycoside hydrolases): strategies and tactics. Methods in Enzymology. 510: 141-68. PMID 22608725 DOI: 10.1016/B978-0-12-415931-0.00008-2 |
0.466 |
|
2012 |
van Bueren AL, Otani S, Friis EP, Wilson KS, Davies GJ. Three-dimensional structure of a thermophilic family GH11 xylanase from Thermobifida fusca. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 68: 141-4. PMID 22297985 DOI: 10.1107/S1744309111049608 |
0.421 |
|
2012 |
Mba Medie F, Davies GJ, Drancourt M, Henrissat B. Genome analyses highlight the different biological roles of cellulases. Nature Reviews. Microbiology. 10: 227-34. PMID 22266780 DOI: 10.1038/Nrmicro2729 |
0.345 |
|
2012 |
Thompson AJ, Williams RJ, Hakki Z, Alonzi DS, Wennekes T, Gloster TM, Songsrirote K, Thomas-Oates JE, Wrodnigg TM, Spreitz J, Stütz AE, Butters TD, Williams SJ, Davies GJ. Structural and mechanistic insight into N-glycan processing by endo-α-mannosidase. Proceedings of the National Academy of Sciences of the United States of America. 109: 781-6. PMID 22219371 DOI: 10.1073/Pnas.1111482109 |
0.447 |
|
2012 |
Davies GJ, Planas A, Rovira C. Conformational analyses of the reaction coordinate of glycosidases. Accounts of Chemical Research. 45: 308-16. PMID 21923088 DOI: 10.1021/Ar2001765 |
0.449 |
|
2012 |
Quach T, Tsegay S, Thompson AJ, Kukushkin NV, Alonzi DS, Butters TD, Davies GJ, Williams SJ. Fleetamine (3-O-α-d-glucopyranosyl-swainsonine): The synthesis of a hypothetical inhibitor of endo-α-mannosidase Tetrahedron Asymmetry. 23: 992-997. DOI: 10.1016/J.Tetasy.2012.06.011 |
0.367 |
|
2011 |
Quinlan RJ, Sweeney MD, Lo Leggio L, Otten H, Poulsen JC, Johansen KS, Krogh KB, Jørgensen CI, Tovborg M, Anthonsen A, Tryfona T, Walter CP, Dupree P, Xu F, Davies GJ, et al. Insights into the oxidative degradation of cellulose by a copper metalloenzyme that exploits biomass components. Proceedings of the National Academy of Sciences of the United States of America. 108: 15079-84. PMID 21876164 DOI: 10.1073/Pnas.1105776108 |
0.685 |
|
2011 |
Lee SS, Hong SY, Errey JC, Izumi A, Davies GJ, Davis BG. Mechanistic evidence for a front-side, SNi-type reaction in a retaining glycosyltransferase. Nature Chemical Biology. 7: 631-8. PMID 21822275 DOI: 10.1038/Nchembio.628 |
0.336 |
|
2011 |
Ariza A, Eklöf JM, Spadiut O, Offen WA, Roberts SM, Besenmatter W, Friis EP, Skjøt M, Wilson KS, Brumer H, Davies G. Structure and activity of Paenibacillus polymyxa xyloglucanase from glycoside hydrolase family 44. The Journal of Biological Chemistry. 286: 33890-900. PMID 21795708 DOI: 10.1074/Jbc.M111.262345 |
0.458 |
|
2011 |
Spadiut O, Ibatullin FM, Peart J, Gullfot F, Martinez-Fleites C, Ruda M, Xu C, Sundqvist G, Davies GJ, Brumer H. Building custom polysaccharides in vitro with an efficient, broad-specificity xyloglucan glycosynthase and a fucosyltransferase. Journal of the American Chemical Society. 133: 10892-900. PMID 21618981 DOI: 10.1021/Ja202788Q |
0.422 |
|
2011 |
Larsbrink J, Izumi A, Ibatullin FM, Nakhai A, Gilbert HJ, Davies GJ, Brumer H. Structural and enzymatic characterization of a glycoside hydrolase family 31 α-xylosidase from Cellvibrio japonicus involved in xyloglucan saccharification. The Biochemical Journal. 436: 567-80. PMID 21426303 DOI: 10.1042/Bj20110299 |
0.446 |
|
2011 |
Nielsen MM, Suits MD, Yang M, Barry CS, Martinez-Fleites C, Tailford LE, Flint JE, Dumon C, Davis BG, Gilbert HJ, Davies GJ. Substrate and metal ion promiscuity in mannosylglycerate synthase. The Journal of Biological Chemistry. 286: 15155-64. PMID 21288903 DOI: 10.1074/Jbc.M110.199844 |
0.336 |
|
2011 |
He Y, Bubb AK, Stubbs KA, Gloster TM, Davies GJ. Inhibition of a bacterial O-GlcNAcase homologue by lactone and lactam derivatives: Structural, kinetic and thermodynamic analyses Amino Acids. 40: 829-839. PMID 20689974 DOI: 10.1007/S00726-010-0700-6 |
0.35 |
|
2010 |
Davies GJ, Martinez-Fleites C. GlaxoSmithKline Award Lecture. The O-GlcNAc modification: three-dimensional structure, enzymology and the development of selective inhibitors to probe disease. Biochemical Society Transactions. 38: 1179-88. PMID 20863281 DOI: 10.1042/Bst0381179 |
0.359 |
|
2010 |
Korczynska JE, Danielsen S, Schagerlöf U, Turkenburg JP, Davies GJ, Wilson KS, Taylor EJ. The structure of a family GH25 lysozyme from Aspergillus fumigatus. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 973-7. PMID 20823508 DOI: 10.1107/S1744309110025601 |
0.417 |
|
2010 |
Montanier C, Flint JE, Bolam DN, Xie H, Liu Z, Rogowski A, Weiner DP, Ratnaparkhe S, Nurizzo D, Roberts SM, Turkenburg JP, Davies GJ, Gilbert HJ. Circular permutation provides an evolutionary link between two families of calcium-dependent carbohydrate binding modules. The Journal of Biological Chemistry. 285: 31742-54. PMID 20659893 DOI: 10.1074/Jbc.M110.142133 |
0.414 |
|
2010 |
Correia MA, Abbott DW, Gloster TM, Fernandes VO, Prates JA, Montanier C, Dumon C, Williamson MP, Tunnicliffe RB, Liu Z, Flint JE, Davies GJ, Henrissat B, Coutinho PM, Fontes CM, et al. Signature active site architectures illuminate the molecular basis for ligand specificity in family 35 carbohydrate binding module. Biochemistry. 49: 6193-205. PMID 20496884 DOI: 10.1021/Bi1006139 |
0.374 |
|
2010 |
Macdonald JM, Tarling CA, Taylor EJ, Dennis RJ, Myers DS, Knapp S, Davies GJ, Withers SG. Chitinase inhibition by chitobiose and chitotriose thiazolines. Angewandte Chemie (International Ed. in English). 49: 2599-602. PMID 20209544 DOI: 10.1002/Anie.200906644 |
0.394 |
|
2010 |
Suits MD, Zhu Y, Taylor EJ, Walton J, Zechel DL, Gilbert HJ, Davies GJ. Structure and kinetic investigation of Streptococcus pyogenes family GH38 alpha-mannosidase. Plos One. 5: e9006. PMID 20140249 DOI: 10.1371/Journal.Pone.0009006 |
0.321 |
|
2010 |
Lammerts van Bueren A, Ardèvol A, Fayers-Kerr J, Luo B, Zhang Y, Sollogoub M, Blériot Y, Rovira C, Davies GJ. Analysis of the reaction coordinate of alpha-L-fucosidases: a combined structural and quantum mechanical approach. Journal of the American Chemical Society. 132: 1804-6. PMID 20092273 DOI: 10.1021/Ja908908Q |
0.329 |
|
2010 |
Zhu Y, Suits MD, Thompson AJ, Chavan S, Dinev Z, Dumon C, Smith N, Moremen KW, Xiang Y, Siriwardena A, Williams SJ, Gilbert HJ, Davies GJ. Mechanistic insights into a Ca2+-dependent family of alpha-mannosidases in a human gut symbiont. Nature Chemical Biology. 6: 125-32. PMID 20081828 DOI: 10.1038/Nchembio.278 |
0.371 |
|
2010 |
Errey JC, Lee SS, Gibson RP, Martinez Fleites C, Barry CS, Jung PM, O'Sullivan AC, Davis BG, Davies GJ. Mechanistic insight into enzymatic glycosyl transfer with retention of configuration through analysis of glycomimetic inhibitors. Angewandte Chemie (International Ed. in English). 49: 1234-7. PMID 20077550 DOI: 10.1002/Anie.200905096 |
0.427 |
|
2010 |
He Y, Macauley MS, Stubbs KA, Vocadlo DJ, Davies GJ. Visualizing the reaction coordinate of an O-GlcNAc hydrolase. Journal of the American Chemical Society. 132: 1807-9. PMID 20067256 DOI: 10.1021/Ja9086769 |
0.302 |
|
2010 |
Gloster TM, Davies GJ. Glycosidase inhibition: assessing mimicry of the transition state. Organic & Biomolecular Chemistry. 8: 305-20. PMID 20066263 DOI: 10.1039/B915870G |
0.347 |
|
2010 |
Martinez-Fleites C, He Y, Davies GJ. Structural analyses of enzymes involved in the O-GlcNAc modification. Biochimica Et Biophysica Acta. 1800: 122-33. PMID 19647042 DOI: 10.1016/J.Bbagen.2009.07.019 |
0.381 |
|
2009 |
Martinez-Fleites C, Korczynska JE, Davies GJ, Cope MJ, Turkenburg JP, Taylor EJ. The crystal structure of a family GH25 lysozyme from Bacillus anthracis implies a neighboring-group catalytic mechanism with retention of anomeric configuration. Carbohydrate Research. 344: 1753-7. PMID 19595298 DOI: 10.1016/J.Carres.2009.06.001 |
0.461 |
|
2009 |
Aguilar-Moncayo M, Gloster TM, Turkenburg JP, García-Moreno MI, Ortiz Mellet C, Davies GJ, García Fernández JM. Glycosidase inhibition by ring-modified castanospermine analogues: tackling enzyme selectivity by inhibitor tailoring. Organic & Biomolecular Chemistry. 7: 2738-47. PMID 19532990 DOI: 10.1039/B906968B |
0.318 |
|
2009 |
Balcewich MD, Stubbs KA, He Y, James TW, Davies GJ, Vocadlo DJ, Mark BL. Insight into a strategy for attenuating AmpC-mediated beta-lactam resistance: structural basis for selective inhibition of the glycoside hydrolase NagZ. Protein Science : a Publication of the Protein Society. 18: 1541-51. PMID 19499593 DOI: 10.1002/Pro.137 |
0.361 |
|
2009 |
Tailford LE, Ducros VM, Flint JE, Roberts SM, Morland C, Zechel DL, Smith N, Bjørnvad ME, Borchert TV, Wilson KS, Davies GJ, Gilbert HJ. Understanding how diverse beta-mannanases recognize heterogeneous substrates. Biochemistry. 48: 7009-18. PMID 19441796 DOI: 10.1021/Bi900515D |
0.448 |
|
2009 |
Gullfot F, Ibatullin FM, Sundqvist G, Davies GJ, Brumer H. Functional characterization of xyloglucan glycosynthases from GH7, GH12, and GH16 scaffolds. Biomacromolecules. 10: 1782-8. PMID 19419143 DOI: 10.1021/Bm900215P |
0.364 |
|
2009 |
Turkenburg JP, Brzozowski AM, Svendsen A, Borchert TV, Davies GJ, Wilson KS. Structure of a pullulanase from Bacillus acidopullulyticus. Proteins. 76: 516-9. PMID 19382205 DOI: 10.1002/Prot.22416 |
0.49 |
|
2009 |
Montanier C, Money VA, Pires VM, Flint JE, Pinheiro BA, Goyal A, Prates JA, Izumi A, Stålbrand H, Morland C, Cartmell A, Kolenova K, Topakas E, Dodson EJ, Bolam DN, ... Davies GJ, et al. The active site of a carbohydrate esterase displays divergent catalytic and noncatalytic binding functions. Plos Biology. 7: e71. PMID 19338387 DOI: 10.1371/Journal.Pbio.1000071 |
0.441 |
|
2009 |
Ling Z, Suits MD, Bingham RJ, Bruce NC, Davies GJ, Fairbanks AJ, Moir JW, Taylor EJ. The X-ray crystal structure of an Arthrobacter protophormiae endo-beta-N-acetylglucosaminidase reveals a (beta/alpha)(8) catalytic domain, two ancillary domains and active site residues key for transglycosylation activity. Journal of Molecular Biology. 389: 1-9. PMID 19327363 DOI: 10.1016/J.Jmb.2009.03.050 |
0.404 |
|
2009 |
Montanier C, van Bueren AL, Dumon C, Flint JE, Correia MA, Prates JA, Firbank SJ, Lewis RJ, Grondin GG, Ghinet MG, Gloster TM, Herve C, Knox JP, Talbot BG, Turkenburg JP, ... ... Davies GJ, et al. Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. Proceedings of the National Academy of Sciences of the United States of America. 106: 3065-70. PMID 19218457 DOI: 10.1073/Pnas.0808972106 |
0.459 |
|
2009 |
He Y, Martinez-Fleites C, Bubb A, Gloster TM, Davies GJ. Structural insight into the mechanism of streptozotocin inhibition of O-GlcNAcase. Carbohydrate Research. 344: 627-31. PMID 19217614 DOI: 10.1016/J.Carres.2008.12.007 |
0.358 |
|
2009 |
Cardona F, Parmeggiani C, Faggi E, Bonaccini C, Gratteri P, Sim L, Gloster TM, Roberts S, Davies GJ, Rose DR, Goti A. Total syntheses of casuarine and its 6-O-alpha-glucoside: complementary inhibition towards glycoside hydrolases of the GH31 and GH37 families. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 1627-36. PMID 19123216 DOI: 10.1002/Chem.200801578 |
0.399 |
|
2009 |
Tailford LE, Ducros VMA, Flint JE, Roberts SM, Morland C, Zechel DL, Smith N, Bjornvad ME, Borchert TV, Wilson KS, Davies GJ, Gilbert HJ. Understanding How Diverse -Mannanases Recognise Heterogeneous Substrates. Biochemistry. 48: 7009. DOI: 10.2210/Pdb2Whj/Pdb |
0.359 |
|
2009 |
Davies GJ, Withers SG, Vocadlo DJ. The chitopentaose complex of a mutant en egg-white lysozyme displays no distortion of the -1 sugar away from a 4C1 chair conformation Australian Journal of Chemistry. 62: 528-532. DOI: 10.1071/Ch09038 |
0.339 |
|
2008 |
Gloster TM, Turkenburg JP, Potts JR, Henrissat B, Davies GJ. Divergence of catalytic mechanism within a glycosidase family provides insight into evolution of carbohydrate metabolism by human gut flora. Chemistry & Biology. 15: 1058-67. PMID 18848471 DOI: 10.1016/J.Chembiol.2008.09.005 |
0.444 |
|
2008 |
Cartmell A, Topakas E, Ducros VM, Suits MD, Davies GJ, Gilbert HJ. The Cellvibrio japonicus mannanase CjMan26C displays a unique exo-mode of action that is conferred by subtle changes to the distal region of the active site. The Journal of Biological Chemistry. 283: 34403-13. PMID 18799462 DOI: 10.1074/Jbc.M804053200 |
0.489 |
|
2008 |
Davies GJ, Naismith JH. Chemistry's prodigal child: enzyme mechanism. Current Opinion in Chemical Biology. 12: 529-31. PMID 18793749 DOI: 10.1016/J.Cbpa.2008.08.018 |
0.367 |
|
2008 |
Ruane KM, Davies GJ, Martinez-Fleites C. Crystal structure of a family GT4 glycosyltransferase from Bacillus anthracis ORF BA1558. Proteins. 73: 784-7. PMID 18712829 DOI: 10.1002/Prot.22171 |
0.33 |
|
2008 |
Vocadlo DJ, Davies GJ. Mechanistic insights into glycosidase chemistry. Current Opinion in Chemical Biology. 12: 539-55. PMID 18558099 DOI: 10.1016/J.Cbpa.2008.05.010 |
0.416 |
|
2008 |
Martinez-Fleites C, Macauley MS, He Y, Shen DL, Vocadlo DJ, Davies GJ. Structure of an O-GlcNAc transferase homolog provides insight into intracellular glycosylation. Nature Structural & Molecular Biology. 15: 764-5. PMID 18536723 DOI: 10.1038/Nsmb.1443 |
0.364 |
|
2008 |
Lairson LL, Henrissat B, Davies GJ, Withers SG. Glycosyltransferases: structures, functions, and mechanisms. Annual Review of Biochemistry. 77: 521-55. PMID 18518825 DOI: 10.1146/annurev.biochem.76.061005.092322 |
0.35 |
|
2008 |
Pinheiro BA, Proctor MR, Martinez-Fleites C, Prates JA, Money VA, Davies GJ, Bayer EA, Fontesm CM, Fierobe HP, Gilbert HJ. The Clostridium cellulolyticum dockerin displays a dual binding mode for its cohesin partner. The Journal of Biological Chemistry. 283: 18422-30. PMID 18445585 DOI: 10.1074/Jbc.M801533200 |
0.355 |
|
2008 |
Money VA, Cartmell A, Guerreiro CI, Ducros VM, Fontes CM, Gilbert HJ, Davies GJ. Probing the beta-1,3:1,4 glucanase, CtLic26A, with a thio-oligosaccharide and enzyme variants. Organic & Biomolecular Chemistry. 6: 851-3. PMID 18292875 DOI: 10.1039/B719288F |
0.444 |
|
2008 |
Davies GJ, Sinnott ML. Sorting the diverse: The sequencebased classifications of carbohydrateactive enzymes The Biochemist. 30: 26-32. DOI: 10.1042/Bj20080382 |
0.423 |
|
2007 |
Brazier-Hicks M, Offen WA, Gershater MC, Revett TJ, Lim EK, Bowles DJ, Davies GJ, Edwards R. Characterization and engineering of the bifunctional N- and O-glucosyltransferase involved in xenobiotic metabolism in plants. Proceedings of the National Academy of Sciences of the United States of America. 104: 20238-43. PMID 18077347 DOI: 10.1073/Pnas.0706421104 |
0.434 |
|
2007 |
Gibson RP, Gloster TM, Roberts S, Warren RA, Storch de Gracia I, García A, Chiara JL, Davies GJ. Molecular basis for trehalase inhibition revealed by the structure of trehalase in complex with potent inhibitors. Angewandte Chemie (International Ed. in English). 46: 4115-9. PMID 17455176 DOI: 10.1002/Anie.200604825 |
0.322 |
|
2007 |
Bolam DN, Roberts S, Proctor MR, Turkenburg JP, Dodson EJ, Martinez-Fleites C, Yang M, Davis BG, Davies GJ, Gilbert HJ. The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity. Proceedings of the National Academy of Sciences of the United States of America. 104: 5336-41. PMID 17376874 DOI: 10.1073/Pnas.0607897104 |
0.373 |
|
2007 |
Gloster TM, Ibatullin FM, Macauley K, Eklöf JM, Roberts S, Turkenburg JP, Bjørnvad ME, Jørgensen PL, Danielsen S, Johansen KS, Borchert TV, Wilson KS, Brumer H, Davies GJ. Characterization and three-dimensional structures of two distinct bacterial xyloglucanases from families GH5 and GH12. The Journal of Biological Chemistry. 282: 19177-89. PMID 17376777 DOI: 10.1074/Jbc.M700224200 |
0.456 |
|
2007 |
Carvalho AL, Dias FM, Nagy T, Prates JA, Proctor MR, Smith N, Bayer EA, Davies GJ, Ferreira LM, Romão MJ, Fontes CM, Gilbert HJ. Evidence for a dual binding mode of dockerin modules to cohesins. Proceedings of the National Academy of Sciences of the United States of America. 104: 3089-94. PMID 17360613 DOI: 10.1073/Pnas.0611173104 |
0.403 |
|
2007 |
Yang M, Davies GJ, Davis BG. A glycosynthase catalyst for the synthesis of flavonoid glycosides. Angewandte Chemie (International Ed. in English). 46: 3885-8. PMID 17304599 DOI: 10.1002/Anie.200604177 |
0.411 |
|
2007 |
Tailford LE, Money VA, Smith NL, Dumon C, Davies GJ, Gilbert HJ. Mannose foraging by Bacteroides thetaiotaomicron: structure and specificity of the beta-mannosidase, BtMan2A. The Journal of Biological Chemistry. 282: 11291-9. PMID 17287210 DOI: 10.1074/Jbc.M610964200 |
0.509 |
|
2007 |
Gloster TM, Meloncelli P, Stick RV, Zechel D, Vasella A, Davies GJ. Glycosidase inhibition: an assessment of the binding of 18 putative transition-state mimics. Journal of the American Chemical Society. 129: 2345-54. PMID 17279749 DOI: 10.1021/Ja066961G |
0.391 |
|
2007 |
Whitworth GE, Macauley MS, Stubbs KA, Dennis RJ, Taylor EJ, Davies GJ, Greig IR, Vocadlo DJ. Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise. Journal of the American Chemical Society. 129: 635-44. PMID 17227027 DOI: 10.1021/Ja065697O |
0.334 |
|
2007 |
Oberbarnscheidt L, Taylor EJ, Davies GJ, Gloster TM. Structure of a carbohydrate esterase from Bacillus anthracis. Proteins. 66: 250-2. PMID 17063474 DOI: 10.1002/Prot.21217 |
0.489 |
|
2007 |
Vincent F, Yates D, Garman E, Davies GJ. The Three-Dimensional Structure of the N-Acetylglucosamine-6-Phosphate Deacetylase from Bacillus Subtilis Journal of Biological Chemistry. 279: 2809. DOI: 10.2210/Pdb2Vhl/Pdb |
0.442 |
|
2007 |
Meloncelli PJ, Gloster TM, Money VA, Tarling CA, Davies GJ, Withers SG, Stick RV. D-glucosylated derivatives of isofagomine and noeuromycin and their potential as inhibitors of β-glycoside hydrolases Australian Journal of Chemistry. 60: 549-565. DOI: 10.1071/Ch07188 |
0.347 |
|
2006 |
Gloster TM, Madsen R, Davies GJ. Structural basis for cyclophellitol inhibition of a beta-glucosidase. Organic & Biomolecular Chemistry. 5: 444-6. PMID 17252125 DOI: 10.1039/B616590G |
0.345 |
|
2006 |
Martinez-Fleites C, Proctor M, Roberts S, Bolam DN, Gilbert HJ, Davies GJ. Insights into the synthesis of lipopolysaccharide and antibiotics through the structures of two retaining glycosyltransferases from family GT4. Chemistry & Biology. 13: 1143-52. PMID 17113996 DOI: 10.1016/J.Chembiol.2006.09.005 |
0.469 |
|
2006 |
Shanmugasundaram B, Debowski AW, Dennis RJ, Davies GJ, Vocadlo DJ, Vasella A. Inhibition of O-GlcNAcase by a gluco-configured nagstatin and a PUGNAc-imidazole hybrid inhibitor. Chemical Communications (Cambridge, England). 4372-4. PMID 17057847 DOI: 10.1039/B612154C |
0.351 |
|
2006 |
Gloster TM, Roberts S, Perugino G, Rossi M, Moracci M, Panday N, Terinek M, Vasella A, Davies GJ. Structural, kinetic, and thermodynamic analysis of glucoimidazole-derived glycosidase inhibitors. Biochemistry. 45: 11879-84. PMID 17002288 DOI: 10.1021/Bi060973X |
0.357 |
|
2006 |
Money VA, Smith NL, Scaffidi A, Stick RV, Gilbert HJ, Davies GJ. Substrate distortion by a lichenase highlights the different conformational itineraries harnessed by related glycoside hydrolases. Angewandte Chemie (International Ed. in English). 45: 5136-40. PMID 16823793 DOI: 10.1002/Anie.200600802 |
0.459 |
|
2006 |
Sheldon WL, Macauley MS, Taylor EJ, Robinson CE, Charnock SJ, Davies GJ, Vocadlo DJ, Black GW. Functional analysis of a group A streptococcal glycoside hydrolase Spy1600 from family 84 reveals it is a beta-N-acetylglucosaminidase and not a hyaluronidase. The Biochemical Journal. 399: 241-7. PMID 16822234 DOI: 10.1042/Bj20060307 |
0.406 |
|
2006 |
Martinez-Fleites C, Guerreiro CIPD, Baumann MJ, Taylor EJ, Prates JAM, Ferreira LMA, Fontes CMGA, Brumer H, Davies GJ. Crystal structures of Clostridium thermocellum xyloglucanase, XGH74A, reveal the structural basis for xyloglucan recognition and degradation Journal of Biological Chemistry. 281: 24922-24933. PMID 16772298 DOI: 10.1074/Jbc.M603583200 |
0.431 |
|
2006 |
Henshaw J, Horne-Bitschy A, van Bueren AL, Money VA, Bolam DN, Czjzek M, Ekborg NA, Weiner RM, Hutcheson SW, Davies GJ, Boraston AB, Gilbert HJ. Family 6 carbohydrate binding modules in beta-agarases display exquisite selectivity for the non-reducing termini of agarose chains. The Journal of Biological Chemistry. 281: 17099-107. PMID 16601125 DOI: 10.1074/Jbc.M600702200 |
0.417 |
|
2006 |
Dennis RJ, Taylor EJ, Macauley MS, Stubbs KA, Turkenburg JP, Hart SJ, Black GN, Vocadlo DJ, Davies GJ. Structure and mechanism of a bacterial beta-glucosaminidase having O-GlcNAcase activity. Nature Structural & Molecular Biology. 13: 365-71. PMID 16565725 DOI: 10.1038/Nsmb1079 |
0.396 |
|
2006 |
Offen W, Martinez-Fleites C, Yang M, Kiat-Lim E, Davis BG, Tarling CA, Ford CM, Bowles DJ, Davies GJ. Structure of a flavonoid glucosyltransferase reveals the basis for plant natural product modification Embo Journal. 25: 1396-1405. PMID 16482224 DOI: 10.1038/Sj.Emboj.7600970 |
0.433 |
|
2006 |
Taylor EJ, Gloster TM, Turkenburg JP, Vincent F, Brzozowski AM, Dupont C, Shareck F, Centeno MS, Prates JA, Puchart V, Ferreira LM, Fontes CM, Biely P, Davies GJ. Structure and activity of two metal ion-dependent acetylxylan esterases involved in plant cell wall degradation reveals a close similarity to peptidoglycan deacetylases. The Journal of Biological Chemistry. 281: 10968-75. PMID 16431911 DOI: 10.1074/Jbc.M513066200 |
0.429 |
|
2006 |
Taylor EJ, Smith NL, Turkenburg JP, D'Souza S, Gilbert HJ, Davies GJ. Structural insight into the ligand specificity of a thermostable family 51 arabinofuranosidase, Araf51, from Clostridium thermocellum. The Biochemical Journal. 395: 31-7. PMID 16336192 DOI: 10.1042/Bj20051780 |
0.467 |
|
2005 |
Smith NL, Taylor EJ, Lindsay AM, Charnock SJ, Turkenburg JP, Dodson EJ, Davies GJ, Black GW. Structure of a group A streptococcal phage-encoded virulence factor reveals a catalytically active triple-stranded beta-helix. Proceedings of the National Academy of Sciences of the United States of America. 102: 17652-7. PMID 16314578 DOI: 10.1073/Pnas.0504782102 |
0.346 |
|
2005 |
Davies GJ, Gloster TM, Henrissat B. Recent structural insights into the expanding world of carbohydrate-active enzymes. Current Opinion in Structural Biology. 15: 637-45. PMID 16263268 DOI: 10.1016/J.Sbi.2005.10.008 |
0.469 |
|
2005 |
Taylor EJ, Goyal A, Guerreiro CI, Prates JA, Money VA, Ferry N, Morland C, Planas A, Macdonald JA, Stick RV, Gilbert HJ, Fontes CM, Davies GJ. How family 26 glycoside hydrolases orchestrate catalysis on different polysaccharides: structure and activity of a Clostridium thermocellum lichenase, CtLic26A. The Journal of Biological Chemistry. 280: 32761-7. PMID 15987675 DOI: 10.1074/Jbc.M506580200 |
0.452 |
|
2005 |
Flint J, Taylor E, Yang M, Bolam DN, Tailford LE, Martinez-Fleites C, Dodson EJ, Davis BG, Gilbert HJ, Davies GJ. Structural dissection and high-throughput screening of mannosylglycerate synthase. Nature Structural & Molecular Biology. 12: 608-14. PMID 15951819 DOI: 10.1038/Nsmb950 |
0.383 |
|
2005 |
Carvalho AL, Pires VM, Gloster TM, Turkenburg JP, Prates JA, Ferreira LM, Romão MJ, Davies GJ, Fontes CM, Gilbert HJ. Insights into the structural determinants of cohesin-dockerin specificity revealed by the crystal structure of the type II cohesin from Clostridium thermocellum SdbA. Journal of Molecular Biology. 349: 909-15. PMID 15913653 DOI: 10.1016/J.Jmb.2005.04.037 |
0.365 |
|
2005 |
Martínez-Fleites C, Ortíz-Lombardía M, Pons T, Tarbouriech N, Taylor EJ, Arrieta JG, Hernández L, Davies GJ. Crystal structure of levansucrase from the Gram-negative bacterium Gluconacetobacter diazotrophicus. The Biochemical Journal. 390: 19-27. PMID 15869470 DOI: 10.1042/Bj20050324 |
0.45 |
|
2005 |
Varrot A, Leydier S, Pell G, Macdonald JM, Stick RV, Henrissat B, Gilbert HJ, Davies GJ. Mycobacterium tuberculosis strains possess functional cellulases. The Journal of Biological Chemistry. 280: 20181-4. PMID 15824123 DOI: 10.1074/Jbc.C500142200 |
0.379 |
|
2005 |
Flint J, Bolam DN, Nurizzo D, Taylor EJ, Williamson MP, Walters C, Davies GJ, Gilbert HJ. Probing the mechanism of ligand recognition in family 29 carbohydrate-binding modules. The Journal of Biological Chemistry. 280: 23718-26. PMID 15784618 DOI: 10.1074/Jbc.M501551200 |
0.39 |
|
2005 |
Vincent F, Davies GJ, Brannigan JA. Structure and kinetics of a monomeric glucosamine 6-phosphate deaminase: missing link of the NagB superfamily? The Journal of Biological Chemistry. 280: 19649-55. PMID 15755726 DOI: 10.1074/Jbc.M502131200 |
0.424 |
|
2005 |
Proctor MR, Taylor EJ, Nurizzo D, Turkenburg JP, Lloyd RM, Vardakou M, Davies GJ, Gilbert HJ. Tailored catalysts for plant cell-wall degradation: Redesigning the exo/endo preference of Cellvibrio japonicus arabinanase 43A Proceedings of the National Academy of Sciences of the United States of America. 102: 2697-2702. PMID 15708971 DOI: 10.1073/Pnas.0500051102 |
0.402 |
|
2005 |
Tarbouriech N, Prates JA, Fontes CM, Davies GJ. Molecular determinants of substrate specificity in the feruloyl esterase module of xylanase 10B from Clostridium thermocellum. Acta Crystallographica. Section D, Biological Crystallography. 61: 194-7. PMID 15681871 DOI: 10.1107/S0907444904029695 |
0.409 |
|
2005 |
Davies GJ, Brzozowski AM, Dauter Z, Rasmussen MD, Borchert TV, Wilson KS. Structure of a Bacillus halmapalus family 13 alpha-amylase, BHA, in complex with an acarbose-derived nonasaccharide at 2.1 A resolution. Acta Crystallographica. Section D, Biological Crystallography. 61: 190-3. PMID 15681870 DOI: 10.1107/S0907444904027118 |
0.348 |
|
2005 |
Varrot A, Yip VL, Li Y, Rajan SS, Yang X, Anderson WF, Thompson J, Withers SG, Davies GJ. NAD+ and metal-ion dependent hydrolysis by family 4 glycosidases: structural insight into specificity for phospho-beta-D-glucosides. Journal of Molecular Biology. 346: 423-35. PMID 15670594 DOI: 10.1016/J.Jmb.2004.11.058 |
0.396 |
|
2005 |
Davies GJ, Gamblin SJ, Littlechild JA, Dauter Z, Wilson KS, Watson HC. Structure of the ADP complex of the 3-phosphoglycerate kinase from Bacillus stearothermophilus at 1.65 A. Acta Crystallographica. Section D, Biological Crystallography. 50: 202-9. PMID 15299460 DOI: 10.1107/S0907444993011138 |
0.444 |
|
2005 |
Money VA, Taylor EJ, Fontes CMGA, Gilbert HJ, Davies GJ. Structural insights into a glysoside hydrolase family 26 lichenase Acta Crystallographica Section a Foundations of Crystallography. 61: c207-c207. DOI: 10.1107/S0108767305091178 |
0.354 |
|
2004 |
Vincent F, Gloster TM, Macdonald J, Morland C, Stick RV, Dias FM, Prates JA, Fontes CM, Gilbert HJ, Davies GJ. Common inhibition of both beta-glucosidases and beta-mannosidases by isofagomine lactam reflects different conformational itineraries for pyranoside hydrolysis. Chembiochem : a European Journal of Chemical Biology. 5: 1596-9. PMID 15515081 DOI: 10.1002/Cbic.200400169 |
0.366 |
|
2004 |
Andrews SR, Taylor EJ, Pell G, Vincent F, Ducros VMA, Davies GJ, Lakey JH, Gilbert HJ. The use of forced protein evolution to investigate and improve stability of family 10 xylanases: The production of Ca2--independent stable xylanases Journal of Biological Chemistry. 279: 54369-54379. PMID 15452124 DOI: 10.1074/Jbc.M409044200 |
0.356 |
|
2004 |
Gloster TM, Macdonald JM, Tarling CA, Stick RV, Withers SG, Davies GJ. Structural, thermodynamic, and kinetic analyses of tetrahydrooxazine-derived inhibitors bound to beta-glucosidases. The Journal of Biological Chemistry. 279: 49236-42. PMID 15356002 DOI: 10.1074/Jbc.M407195200 |
0.422 |
|
2004 |
Rajan SS, Yang X, Collart F, Yip VL, Withers SG, Varrot A, Thompson J, Davies GJ, Anderson WF. Novel catalytic mechanism of glycoside hydrolysis based on the structure of an NAD+/Mn2+ -dependent phospho-alpha-glucosidase from Bacillus subtilis. Structure (London, England : 1993). 12: 1619-29. PMID 15341727 DOI: 10.1016/J.Str.2004.06.020 |
0.427 |
|
2004 |
Gloster TM, Williams SJ, Roberts S, Tarling CA, Wicki J, Withers SG, Davies GJ. Atomic resolution analyses of the binding of xylobiose-derived deoxynojirimycin and isofagomine to xylanase Xyn10A. Chemical Communications (Cambridge, England). 1794-5. PMID 15306887 DOI: 10.1039/B405152A |
0.378 |
|
2004 |
Jamal-Talabani S, Boraston AB, Turkenburg JP, Tarbouriech N, Ducros VM, Davies GJ. Ab initio structure determination and functional characterization of CBM36; a new family of calcium-dependent carbohydrate binding modules. Structure (London, England : 1993). 12: 1177-87. PMID 15242594 DOI: 10.1016/J.Str.2004.04.022 |
0.391 |
|
2004 |
Yip VL, Varrot A, Davies GJ, Rajan SS, Yang X, Thompson J, Anderson WF, Withers SG. An unusual mechanism of glycoside hydrolysis involving redox and elimination steps by a family 4 beta-glycosidase from Thermotoga maritima. Journal of the American Chemical Society. 126: 8354-5. PMID 15237973 DOI: 10.1021/Ja047632W |
0.421 |
|
2004 |
Boraston AB, Bolam DN, Gilbert HJ, Davies GJ. Carbohydrate-binding modules: fine-tuning polysaccharide recognition. The Biochemical Journal. 382: 769-81. PMID 15214846 DOI: 10.1042/Bj20040892 |
0.468 |
|
2004 |
Gloster TM, Roberts S, Ducros VM, Perugino G, Rossi M, Hoos R, Moracci M, Vasella A, Davies GJ. Structural studies of the beta-glycosidase from Sulfolobus solfataricus in complex with covalently and noncovalently bound inhibitors. Biochemistry. 43: 6101-9. PMID 15147194 DOI: 10.1021/Bi049666M |
0.441 |
|
2004 |
Jamal S, Nurizzo D, Boraston AB, Davies GJ. X-ray crystal structure of a non-crystalline cellulose-specific carbohydrate-binding module: CBM28. Journal of Molecular Biology. 339: 253-8. PMID 15136030 DOI: 10.1016/J.Jmb.2004.03.069 |
0.417 |
|
2004 |
Dias FMV, Vincent F, Pell G, Prates JAM, Centeno MSJ, Tailford LE, Ferreira LMA, Fontes CMGA, Davies GJ, Gilbert HJ. Insights into the molecular determinants of substrate specificity in glycoside hydrolase family 5 revealed by the crystal structure and kinetics of Cellvibrio mixtus mannosidase 5A Journal of Biological Chemistry. 279: 25517-25526. PMID 15014076 DOI: 10.1074/Jbc.M401647200 |
0.463 |
|
2004 |
Flint J, Nurizzo D, Harding SE, Longman E, Davies GJ, Gilbert HJ, Bolam DN. Ligand-mediated dimerization of a carbohydrate-binding molecule reveals a novel mechanism for protein-carbohydrate recognition. Journal of Molecular Biology. 337: 417-26. PMID 15003456 DOI: 10.1016/J.Jmb.2003.12.081 |
0.352 |
|
2004 |
Pell G, Szabo L, Charnock SJ, Xie H, Gloster TM, Davies GJ, Gilbert HJ. Structural and biochemical analysis of Cellvibrio japonicus Xylanase 10C: How variation in substrate-binding cleft influences the catalytic profile of family GH-10 xylanases Journal of Biological Chemistry. 279: 11777-11788. PMID 14670951 DOI: 10.1074/Jbc.M311947200 |
0.488 |
|
2004 |
Pell G, Taylor EJ, Gloster TM, Turkenburg JP, Fontes CM, Ferreira LM, Nagy T, Clark SJ, Davies GJ, Gilbert HJ. The mechanisms by which family 10 glycoside hydrolases bind decorated substrates. The Journal of Biological Chemistry. 279: 9597-605. PMID 14668328 DOI: 10.1074/Jbc.M312278200 |
0.512 |
|
2004 |
Charnock SJ, Henrissat B, Davies GJ. Three-dimensional structures of UDP-sugar glycosyltransferases illuminate the biosynthesis of plant polysaccharides. Plant Physiology. 125: 527-31. PMID 11161010 DOI: 10.1104/Pp.125.2.527 |
0.303 |
|
2003 |
Zechel DL, Boraston AB, Gloster T, Boraston CM, Macdonald JM, Tilbrook DM, Stick RV, Davies GJ. Iminosugar glycosidase inhibitors: structural and thermodynamic dissection of the binding of isofagomine and 1-deoxynojirimycin to beta-glucosidases. Journal of the American Chemical Society. 125: 14313-23. PMID 14624580 DOI: 10.1021/Ja036833H |
0.389 |
|
2003 |
Carvalho AL, Dias FM, Prates JA, Nagy T, Gilbert HJ, Davies GJ, Ferreira LM, Romão MJ, Fontes CM. Cellulosome assembly revealed by the crystal structure of the cohesin-dockerin complex. Proceedings of the National Academy of Sciences of the United States of America. 100: 13809-14. PMID 14623971 DOI: 10.1073/Pnas.1936124100 |
0.406 |
|
2003 |
Gibson RP, Tarling CA, Roberts S, Withers SG, Davies GJ. The donor subsite of trehalose-6-phosphate synthase: binary complexes with UDP-glucose and UDP-2-deoxy-2-fluoro-glucose at 2 A resolution. The Journal of Biological Chemistry. 279: 1950-5. PMID 14570926 DOI: 10.1074/Jbc.M307643200 |
0.377 |
|
2003 |
Vincent F, Yates D, Garman E, Davies GJ, Brannigan JA. The three-dimensional structure of the N-acetylglucosamine-6-phosphate deacetylase, NagA, from Bacillus subtilis: a member of the urease superfamily. The Journal of Biological Chemistry. 279: 2809-16. PMID 14557261 DOI: 10.1074/Jbc.M310165200 |
0.445 |
|
2003 |
Ducros VM, Tarling CA, Zechel DL, Brzozowski AM, Frandsen TP, von Ossowski I, Schülein M, Withers SG, Davies GJ. Anatomy of glycosynthesis: structure and kinetics of the Humicola insolens Cel7B E197A and E197S glycosynthase mutants. Chemistry & Biology. 10: 619-28. PMID 12890535 DOI: 10.1016/S1074-5521(03)00143-1 |
0.382 |
|
2003 |
Vincent F, Charnock SJ, Verschueren KH, Turkenburg JP, Scott DJ, Offen WA, Roberts S, Pell G, Gilbert HJ, Davies GJ, Brannigan JA. Multifunctional xylooligosaccharide/cephalosporin C deacetylase revealed by the hexameric structure of the Bacillus subtilis enzyme at 1.9A resolution. Journal of Molecular Biology. 330: 593-606. PMID 12842474 DOI: 10.1016/S0022-2836(03)00632-6 |
0.502 |
|
2003 |
Varrot A, Frandsen TP, von Ossowski I, Boyer V, Cottaz S, Driguez H, Schülein M, Davies GJ. Structural basis for ligand binding and processivity in cellobiohydrolase Cel6A from Humicola insolens. Structure (London, England : 1993). 11: 855-64. PMID 12842048 DOI: 10.1016/S0969-2126(03)00124-2 |
0.393 |
|
2003 |
Jahn M, Stoll D, Warren RA, Szabó L, Singh P, Gilbert HJ, Ducros VM, Davies GJ, Withers SG. Expansion of the glycosynthase repertoire to produce defined manno-oligosaccharides. Chemical Communications (Cambridge, England). 1327-9. PMID 12841226 DOI: 10.1039/B302380J |
0.305 |
|
2003 |
Varrot A, Tarling CA, Macdonald JM, Stick RV, Zechel DL, Withers SG, Davies GJ. Direct observation of the protonation state of an imino sugar glycosidase inhibitor upon binding. Journal of the American Chemical Society. 125: 7496-7. PMID 12812472 DOI: 10.1021/Ja034917K |
0.352 |
|
2003 |
Boraston AB, Revett TJ, Boraston CM, Nurizzo D, Davies GJ. Structural and thermodynamic dissection of specific mannan recognition by a carbohydrate binding module, TmCBM27. Structure (London, England : 1993). 11: 665-75. PMID 12791255 DOI: 10.1016/S0969-2126(03)00100-X |
0.376 |
|
2003 |
Davies GJ, Ducros VMA, Varrot A, Zechel DL. Mapping the conformational itinerary of β-glycosidases by X-ray crystallography Biochemical Society Transactions. 31: 523-527. PMID 12773149 DOI: 10.1042/Bst0310523 |
0.388 |
|
2003 |
Gloster T, Williams SJ, Tarling CA, Roberts S, Dupont C, Jodoin P, Shareck F, Withers SG, Davies GJ. A xylobiose-derived isofagomine lactam glycosidase inhibitor binds as its amide tautomer. Chemical Communications (Cambridge, England). 944-5. PMID 12744311 DOI: 10.1039/B301829F |
0.405 |
|
2003 |
Coutinho PM, Deleury E, Davies GJ, Henrissat B. An evolving hierarchical family classification for glycosyltransferases. Journal of Molecular Biology. 328: 307-17. PMID 12691742 DOI: 10.1016/S0022-2836(03)00307-3 |
0.446 |
|
2003 |
Nagy T, Nurizzo D, Davies GJ, Biely P, Lakey JH, Bolam DN, Gilbert HJ. The alpha-glucuronidase, GlcA67A, of Cellvibrio japonicus utilizes the carboxylate and methyl groups of aldobiouronic acid as important substrate recognition determinants. The Journal of Biological Chemistry. 278: 20286-92. PMID 12654910 DOI: 10.1074/Jbc.M302205200 |
0.417 |
|
2003 |
Boraston AB, Notenboom V, Warren RA, Kilburn DG, Rose DR, Davies G. Structure and ligand binding of carbohydrate-binding module CsCBM6-3 reveals similarities with fucose-specific lectins and "galactose-binding" domains. Journal of Molecular Biology. 327: 659-69. PMID 12634060 DOI: 10.1016/S0022-2836(03)00152-9 |
0.375 |
|
2003 |
Varrot A, Davies GJ. Direct experimental observation of the hydrogen-bonding network of a glycosidase along its reaction coordinate revealed by atomic resolution analyses of endoglucanase Cel5A. Acta Crystallographica. Section D, Biological Crystallography. 59: 447-52. PMID 12595701 DOI: 10.1107/S0907444902023405 |
0.395 |
|
2003 |
Gibson RP, Turkenburg JP, Charnock SJ, Lloyd R, Davies GJ. Insights into trehalose synthesis provided by the structure of the retaining glucosyltransferase OtsA. Chemistry & Biology. 9: 1337-46. PMID 12498887 DOI: 10.1016/S1074-5521(02)00292-2 |
0.361 |
|
2002 |
Varrot A, Frandsen TP, Driguez H, Davies GJ. Structure of the Humicola insolens cellobiohydrolase Cel6A D416A mutant in complex with a non-hydrolysable substrate analogue, methyl cellobiosyl-4-thio-beta-cellobioside, at 1.9 A. Acta Crystallographica. Section D, Biological Crystallography. 58: 2201-4. PMID 12454501 DOI: 10.1107/S0907444902017006 |
0.453 |
|
2002 |
Vasella A, Davies GJ, Böhm M. Glycosidase mechanisms. Current Opinion in Chemical Biology. 6: 619-29. PMID 12413546 |
0.308 |
|
2002 |
Charnock SJ, Bolam DN, Nurizzo D, Szabó L, McKie VA, Gilbert HJ, Davies GJ. Promiscuity in ligand-binding: The three-dimensional structure of a Piromyces carbohydrate-binding module, CBM29-2, in complex with cello-and mannohexaose Proceedings of the National Academy of Sciences of the United States of America. 99: 14077-14082. PMID 12391332 DOI: 10.1073/Pnas.212516199 |
0.415 |
|
2002 |
Charnock SJ, Brown IE, Turkenburg JP, Black GW, Davies GJ. Convergent evolution sheds light on the anti-beta -elimination mechanism common to family 1 and 10 polysaccharide lyases. Proceedings of the National Academy of Sciences of the United States of America. 99: 12067-72. PMID 12221284 DOI: 10.1073/Pnas.182431199 |
0.433 |
|
2002 |
Ducros VM, Zechel DL, Murshudov GN, Gilbert HJ, Szabó L, Stoll D, Withers SG, Davies GJ. Substrate distortion by a beta-mannanase: snapshots of the Michaelis and covalent-intermediate complexes suggest a B(2,5) conformation for the transition state. Angewandte Chemie (International Ed. in English). 41: 2824-7. PMID 12203498 DOI: 10.1002/1521-3773(20020802)41:15<2824::Aid-Anie2824>3.0.Co;2-G |
0.305 |
|
2002 |
Nurizzo D, Turkenburg JP, Charnock SJ, Roberts SM, Dodson EJ, McKie VA, Taylor EJ, Gilbert HJ, Davies GJ. Cellvibrio japonicus α-L-arabinanase 43A has a novel five-blade β-propeller fold Nature Structural Biology. 9: 665-668. PMID 12198486 DOI: 10.1038/Nsb835 |
0.376 |
|
2002 |
Boraston AB, Nurizzo D, Notenboom V, Ducros V, Rose DR, Kilburn DG, Davies GJ. Differential oligosaccharide recognition by evolutionarily-related beta-1,4 and beta-1,3 glucan-binding modules. Journal of Molecular Biology. 319: 1143-56. PMID 12079353 DOI: 10.1016/S0022-2836(02)00374-1 |
0.388 |
|
2002 |
Nurizzo D, Nagy T, Gilbert HJ, Davies GJ. The structural basis for catalysis and specificity of the Pseudomonas cellulosa alpha-glucuronidase, GlcA67A. Structure (London, England : 1993). 10: 547-56. PMID 11937059 DOI: 10.1016/S0969-2126(02)00742-6 |
0.396 |
|
2002 |
Gibson RP, Lloyd RM, Charnock SJ, Davies GJ. Characterization of Escherichia coli OtsA, a trehalose-6-phosphate synthase from glycosyltransferase family 20. Acta Crystallographica. Section D, Biological Crystallography. 58: 349-51. PMID 11807274 DOI: 10.1107/S090744490102056X |
0.313 |
|
2002 |
Prates JA, Tarbouriech N, Charnock SJ, Fontes CM, Ferreira LM, Davies GJ. The structure of the feruloyl esterase module of xylanase 10B from Clostridium thermocellum provides insights into substrate recognition. Structure (London, England : 1993). 9: 1183-90. PMID 11738044 DOI: 10.1016/S0969-2126(01)00684-0 |
0.401 |
|
2002 |
Tarbouriech N, Charnock SJ, Davies GJ. Three-dimensional structures of the Mn and Mg dTDP complexes of the family GT-2 glycosyltransferase SpsA: a comparison with related NDP-sugar glycosyltransferases. Journal of Molecular Biology. 314: 655-61. PMID 11733986 DOI: 10.1006/Jmbi.2001.5159 |
0.459 |
|
2002 |
Davies GJ. Structural genomics of carbohydrate-active enzymes: implications for the synthesis of plant polysaccharides Biochemical Society Transactions. 30: A24-A24. DOI: 10.1042/Bst030A024C |
0.398 |
|
2002 |
Davies GJ, Henrissat B. Structural enzymology of carbohydrate-active enzymes: implications for the post-genomic era Biochemical Society Transactions. 30: 291-297. DOI: 10.1042/Bst0300291 |
0.464 |
|
2001 |
Fort S, Varrot A, Schülein M, Cottaz S, Driguez H, Davies GJ. Mixed-linkage cellooligosaccharides: a new class of glycoside hydrolase inhibitors. Chembiochem : a European Journal of Chemical Biology. 2: 319-25. PMID 11828460 DOI: 10.1002/1439-7633(20010504)2:5<319::Aid-Cbic319>3.0.Co;2-Q |
0.301 |
|
2001 |
Varrot A, Schülein M, Fruchard S, Driguez H, Davies GJ. Atomic resolution structure of endoglucanase Cel5A in complex with methyl 4,4II,4III,4IV-tetrathio-alpha-cellopentoside highlights the alternative binding modes targeted by substrate mimics. Acta Crystallographica. Section D, Biological Crystallography. 57: 1739-42. PMID 11679762 DOI: 10.1107/S0907444901013993 |
0.383 |
|
2001 |
Szabó L, Jamal S, Xie H, Charnock SJ, Bolam DN, Gilbert HJ, Davies GJ. Structure of a family 15 carbohydrate-binding module in complex with xylopentaose: Evidence that xylan binds in an approximate 3-fold helical conformation Journal of Biological Chemistry. 276: 49061-49065. PMID 11598143 DOI: 10.1074/Jbc.M109558200 |
0.403 |
|
2001 |
Sabini E, Wilson KS, Danielsen S, Schülein M, Davies GJ. Oligosaccharide binding to family 11 xylanases: both covalent intermediate and mutant product complexes display (2,5)B conformations at the active centre. Acta Crystallographica. Section D, Biological Crystallography. 57: 1344-7. PMID 11526340 DOI: 10.1107/S0907444901010873 |
0.441 |
|
2001 |
Vocadlo DJ, Davies GJ, Laine R, Withers SG. Catalysis by hen egg-white lysozyme proceeds via a covalent intermediate. Nature. 412: 835-8. PMID 11518970 DOI: 10.1038/35090602 |
0.437 |
|
2001 |
Williams SJ, Davies GJ. Protein--carbohydrate interactions: learning lessons from nature. Trends in Biotechnology. 19: 356-62. PMID 11513999 DOI: 10.1016/S0167-7799(01)01699-7 |
0.319 |
|
2001 |
Xie H, Gilbert HJ, Charnock SJ, Davies GJ, Williamson MP, Simpson PJ, Raghothama S, Fontes CM, Dias FM, Ferreira LM, Bolam DN. Clostridium thermocellum Xyn10B carbohydrate-binding module 22-2: the role of conserved amino acids in ligand binding. Biochemistry. 40: 9167-76. PMID 11478884 DOI: 10.1021/Bi0106742 |
0.45 |
|
2001 |
Charnock SJ, Brown IE, Turkenburg JP, Black GW, Davies GJ. Characterization of a novel pectate lyase, Pel10A, from Pseudomonas cellulosa. Acta Crystallographica. Section D, Biological Crystallography. 57: 1141-3. PMID 11468399 DOI: 10.1107/S0907444901007491 |
0.396 |
|
2001 |
Taylor EJ, Charnock SJ, Colby J, Davies GJ, Black GW. Cloning, purification and characterization of the 6-phospho-3-hexulose isomerase YckF from Bacillus subtilis Acta Crystallographica Section D: Biological Crystallography. 57: 1138-1140. PMID 11468398 DOI: 10.1107/S090744490100748X |
0.326 |
|
2001 |
Davies GJ. Sweet secrets of synthesis. Nature Structural Biology. 8: 98-100. PMID 11175889 DOI: 10.1038/84198 |
0.328 |
|
2001 |
Ducros V, Brzozowski AM, Wilson KS, Ostergaard P, Schneider P, Svendson A, Davies GJ. Structure of the laccase from Coprinus cinereus at 1.68 A resolution: evidence for different 'type 2 Cu-depleted' isoforms. Acta Crystallographica. Section D, Biological Crystallography. 57: 333-6. PMID 11173497 DOI: 10.1107/S0907444900013779 |
0.346 |
|
2001 |
Henrissat B, Davies GJ. Glycoside hydrolases and glycosyltransferases. Families, modules, and implications for genomics. Plant Physiology. 124: 1515-9. PMID 11115868 DOI: 10.1104/Pp.124.4.1515 |
0.403 |
|
2001 |
BROWN IE, MALLEN MH, CHARNOCK SJ, DAVIES GJ, BLACK GW. Pectate lyase 10A from Pseudomonas cellulosa is a modular enzyme containing a family 2a carbohydrate-binding module Biochemical Journal. 355: 155-165. DOI: 10.1042/Bj3550155 |
0.372 |
|
2001 |
Henrissat B, Coutinho PM, Davies GJ. A census of carbohydrate-active enzymes in the genome of Arabidopsis thaliana. Plant Molecular Biology. 47: 55-72. DOI: 10.1007/978-94-010-0668-2_4 |
0.44 |
|
2000 |
Ducros V, Charnock SJ, Derewenda U, Derewenda ZS, Dauteri Z, Dupont C, Shareck F, Morosoli R, Kluepfel D, Davies GJ. Substrate specificity in glycoside hydrolase family 10: Structural and kinetic analysis of the streptomyces lividans xylanase 10A Journal of Biological Chemistry. 275: 23020-23026. PMID 10930426 DOI: 10.1074/Jbc.275.30.23020 |
0.459 |
|
2000 |
Brzozowski AM, Lawson DM, Turkenburg JP, Bisgaard-Frantzen H, Svendsen A, Borchert TV, Dauter Z, Wilson KS, Davies GJ. Structural analysis of a chimeric bacterial alpha-amylase. High-resolution analysis of native and ligand complexes. Biochemistry. 39: 9099-107. PMID 10924103 DOI: 10.1021/Bi0000317 |
0.38 |
|
2000 |
Charnock SJ, Bolam DN, Turkenburg JP, Gilbert HJ, Ferreira LM, Davies GJ, Fontes CM. The X6 "thermostabilizing" domains of xylanases are carbohydrate-binding modules: structure and biochemistry of the Clostridium thermocellum X6b domain. Biochemistry. 39: 5013-21. PMID 10819965 DOI: 10.1021/Bi992821Q |
0.408 |
|
2000 |
Andrews SR, Charnock SJ, Lakey JH, Davies GJ, Claeyssens M, Nerinckx W, Underwood M, Sinnott ML, Warren RA, Gilbert HJ. Substrate specificity in glycoside hydrolase family 10. Tyrosine 87 and leucine 314 play a pivotal role in discriminating between glucose and xylose binding in the proximal active site of Pseudomonas cellulosa xylanase 10A. The Journal of Biological Chemistry. 275: 23027-33. PMID 10767281 DOI: 10.1074/Jbc.M000128200 |
0.39 |
|
2000 |
Varrot A, Schülein M, Davies GJ. Insights into ligand-induced conformational change in Cel5A from Bacillus agaradhaerens revealed by a catalytically active crystal form. Journal of Molecular Biology. 297: 819-28. PMID 10731432 DOI: 10.1006/Jmbi.2000.3567 |
0.472 |
|
2000 |
Bompard-Gilles C, Villeret V, Davies GJ, Fanuel L, Joris B, Frère JM, Van Beeumen J. A new variant of the Ntn hydrolase fold revealed by the crystal structure of L-aminopeptidase D-ala-esterase/amidase from Ochrobactrum anthropi. Structure (London, England : 1993). 8: 153-62. PMID 10673442 DOI: 10.1016/S0969-2126(00)00091-5 |
0.319 |
|
2000 |
DAVIES GJ, BRZOZOWSKI AM, DAUTER M, VARROT A, SCHÜLEIN M. Structure and function of Humicola insolens family 6 cellulases: structure of the endoglucanase, Cel6B, at 1.6 Å resolution Biochemical Journal. 348: 201. DOI: 10.1042/Bj3480201 |
0.481 |
|
2000 |
DAVIES GJ, BRZOZOWSKI AM, DAUTER M, VARROT A, SCHÜLEIN M. Structure and function of Humicola insolens family 6 cellulases: structure of the endoglucanase, Cel6B, at 1.6 Å resolution Biochemical Journal. 348: 201-207. DOI: 10.1042/BJ3480201 |
0.378 |
|
2000 |
Fort S, Boyer V, Greffe L, Davies GJ, Moroz O, Christiansen L, Schülein M, Cottaz S, Driguez H. Highly efficient synthesis of β(1 → 4)-oligo- and -polysaccharides using a mutant cellulase Journal of the American Chemical Society. 122: 5429-5437. DOI: 10.1021/Ja9936520 |
0.35 |
|
1999 |
Cutfield SM, Davies GJ, Murshudov G, Anderson BF, Moody PC, Sullivan PA, Cutfield JF. The structure of the exo-beta-(1,3)-glucanase from Candida albicans in native and bound forms: relationship between a pocket and groove in family 5 glycosyl hydrolases. Journal of Molecular Biology. 294: 771-83. PMID 10610795 DOI: 10.1006/Jmbi.1999.3287 |
0.463 |
|
1999 |
Varrot A, Schülein M, Davies GJ. Structural changes of the active site tunnel of Humicola insolens cellobiohydrolase, Cel6A, upon oligosaccharide binding. Biochemistry. 38: 8884-91. PMID 10413461 DOI: 10.1021/Bi9903998 |
0.494 |
|
1999 |
Dauter Z, Dauter M, Brzozowski AM, Christensen S, Borchert TV, Beier L, Wilson KS, Davies GJ. X-ray structure of Novamyl, the five-domain "maltogenic" alpha-amylase from Bacillus stearothermophilus: maltose and acarbose complexes at 1.7A resolution. Biochemistry. 38: 8385-92. PMID 10387084 DOI: 10.1021/Bi990256L |
0.402 |
|
1999 |
Sabini E, Sulzenbacher G, Dauter M, Dauter Z, Jørgensen PL, Schülein M, Dupont C, Davies GJ, Wilson KS. Catalysis and specificity in enzymatic glycoside hydrolysis: a 2,5B conformation for the glycosyl-enzyme intermediate revealed by the structure of the Bacillus agaradhaerens family 11 xylanase. Chemistry & Biology. 6: 483-92. PMID 10381409 DOI: 10.1016/S1074-5521(99)80066-0 |
0.488 |
|
1999 |
Charnock SJ, Davies GJ. Structure of the nucleotide-diphospho-sugar transferase, SpsA from Bacillus subtilis, in native and nucleotide-complexed forms. Biochemistry. 38: 6380-5. PMID 10350455 DOI: 10.1021/Bi990270Y |
0.411 |
|
1999 |
Davies GJ, Wilson KS. Trapped in the act of catalysis Nature Structural Biology. 6: 406-408. PMID 10331861 DOI: 10.1038/8200 |
0.375 |
|
1999 |
Varrot A, Yamamoto H, Sekiguchi J, Thompson J, Davies GJ. Crystallization and preliminary X-ray analysis of the 6-phospho-alpha-glucosidase from Bacillus subtilis. Acta Crystallographica. Section D, Biological Crystallography. 55: 1212-4. PMID 10329789 DOI: 10.1107/S0907444999003790 |
0.301 |
|
1999 |
Sulzenbacher G, Mackenzie LF, Wilson KS, Withers SG, Dupont C, Davies GJ. The crystal structure of a 2-fluorocellotriosyl complex of the Streptomyces lividans endoglucanase CelB2 at 1.2 A resolution. Biochemistry. 38: 4826-33. PMID 10200171 DOI: 10.1021/Bi982648I |
0.438 |
|
1999 |
Charnock SJ, Davies GJ. Cloning, crystallization and preliminary X-ray analysis of a nucleotide-diphospho-sugar transferase spsA from Bacillus subtilis. Acta Crystallographica. Section D, Biological Crystallography. 55: 677-8. PMID 10089467 DOI: 10.1107/S0907444998013006 |
0.336 |
|
1999 |
VARROT A, HASTRUP S, SCHÜLEIN M, DAVIES GJ. Crystal structure of the catalytic core domain of the family 6 cellobiohydrolase II, Cel6A, from Humicola insolens, at 1.92 Å resolution Biochemical Journal. 337: 297-304. DOI: 10.1042/Bj3370297 |
0.497 |
|
1999 |
Varrot A, Schülein M, Pipelier M, Vasella A, Davies GJ. Lateral Protonation of a Glycosidase Inhibitor. Structure of theBacillusagaradhaerensCel5A in Complex with a Cellobiose-Derived Imidazole at 0.97 Å Resolution Journal of the American Chemical Society. 121: 2621-2622. DOI: 10.1021/Ja984238N |
0.326 |
|
1998 |
MacKenzie LF, Sulzenbacher G, Divne C, Jones TA, Wöldike HF, Schülein M, Withers SG, Davies GJ. Crystal structure of the family 7 endoglucanase I (Cel7B) from Humicola insolens at 2.2 A resolution and identification of the catalytic nucleophile by trapping of the covalent glycosyl-enzyme intermediate. The Biochemical Journal. 409-16. PMID 9761741 DOI: 10.1042/Bj3350409 |
0.503 |
|
1998 |
Davies GJ, Mackenzie L, Varrot A, Dauter M, Brzozowski AM, Schülein M, Withers SG. Snapshots along an enzymatic reaction coordinate: analysis of a retaining beta-glycoside hydrolase. Biochemistry. 37: 11707-13. PMID 9718293 DOI: 10.1021/Bi981315I |
0.459 |
|
1998 |
Davies GJ. Structural studies on cellulases. Biochemical Society Transactions. 26: 167-73. PMID 9649742 DOI: 10.1042/Bst0260167 |
0.482 |
|
1998 |
Ducros V, Brzozowski AM, Wilson KS, Brown SH, Ostergaard P, Schneider P, Yaver DS, Pedersen AH, Davies GJ. Crystal structure of the type-2 Cu depleted laccase from Coprinus cinereus at 2.2 A resolution. Nature Structural Biology. 5: 310-6. PMID 9546223 DOI: 10.1038/Nsb0498-310 |
0.359 |
|
1998 |
Davies GJ, Dauter M, Brzozowski AM, Bjørnvad ME, Andersen KV, Schülein M. Structure of the Bacillus agaradherans family 5 endoglucanase at 1.6 A and its cellobiose complex at 2.0 A resolution. Biochemistry. 37: 1926-32. PMID 9485319 DOI: 10.1021/Bi972162M |
0.468 |
|
1998 |
Sulzenbacher G, Shareck F, Morosoli R, Dupont C, Davies GJ. The Streptomyces lividans family 12 endoglucanase: construction of the catalytic cre, expression, and X-ray structure at 1.75 A resolution. Biochemistry. 36: 16032-9. PMID 9440876 DOI: 10.1021/Bi972407V |
0.466 |
|
1997 |
Henrissat B, Davies G. Structural and sequence-based classification of glycoside hydrolases. Current Opinion in Structural Biology. 7: 637-44. PMID 9345621 DOI: 10.1016/S0959-440X(97)80072-3 |
0.455 |
|
1997 |
Davies GJ, Ducros V, Lewis RJ, Borchert TV, Schülein M. Oligosaccharide specificity of a family 7 endoglucanase: insertion of potential sugar-binding subsites. Journal of Biotechnology. 57: 91-100. PMID 9335168 DOI: 10.1016/S0168-1656(97)00092-8 |
0.466 |
|
1997 |
Kleywegt GJ, Zou JY, Divne C, Davies GJ, Sinning I, Stâhlberg J, Reinikainen T, Srisodsuk M, Teeri TT, Jones TA. The crystal structure of the catalytic core domain of endoglucanase I from Trichoderma reesei at 3.6 A resolution, and a comparison with related enzymes. Journal of Molecular Biology. 272: 383-97. PMID 9325098 DOI: 10.1006/Jmbi.1997.1243 |
0.457 |
|
1997 |
Sulzenbacher G, Schülein M, Davies GJ. Structure of the endoglucanase I from Fusarium oxysporum: native, cellobiose, and 3,4-epoxybutyl beta-D-cellobioside-inhibited forms, at 2.3 A resolution. Biochemistry. 36: 5902-11. PMID 9153432 DOI: 10.1021/BI962963+ |
0.473 |
|
1997 |
Mackenzie LF, Davies GJ, Schülein M, Withers SG. Identification of the catalytic nucleophile of endoglucanase I from Fusarium oxysporum by mass spectrometry. Biochemistry. 36: 5893-901. PMID 9153431 DOI: 10.1021/Bi962962H |
0.447 |
|
1996 |
Davies GJ, Dodson G, Moore MH, Tolley SP, Dauter Z, Wilson KS, Rasmussen G, Schülein M. Structure determination and refinement of the Humicola insolens endoglucanase V at 1.5 A resolution. Acta Crystallographica. Section D, Biological Crystallography. 52: 7-17. PMID 15299721 DOI: 10.1107/S0907444995009280 |
0.361 |
|
1996 |
Sulzenbacher G, Driguez H, Henrissat B, Schülein M, Davies GJ. Structure of the Fusarium oxysporum endoglucanase I with a nonhydrolyzable substrate analogue: substrate distortion gives rise to the preferred axial orientation for the leaving group. Biochemistry. 35: 15280-7. PMID 8952478 DOI: 10.1021/Bi961946H |
0.473 |
|
1996 |
Cleasby A, Wonacott A, Skarzynski T, Hubbard RE, Davies GJ, Proudfoot AE, Bernard AR, Payton MA, Wells TN. The x-ray crystal structure of phosphomannose isomerase from Candida albicans at 1.7 angstrom resolution. Nature Structural Biology. 3: 470-9. PMID 8612079 DOI: 10.1038/Nsb0596-470 |
0.379 |
|
1996 |
Subramanya HS, Roper DI, Dauter Z, Dodson EJ, Davies GJ, Wilson KS, Wigley DB. Enzymatic ketonization of 2-hydroxymuconate: specificity and mechanism investigated by the crystal structures of two isomerases. Biochemistry. 35: 792-802. PMID 8547259 DOI: 10.1021/Bi951732K |
0.49 |
|
1996 |
Davies G, Henrissat B. Structures and mechanisms of glycosyl hydrolases. Structure (London, England : 1993). 3: 853-9. PMID 8535779 DOI: 10.1016/S0969-2126(01)00220-9 |
0.424 |
|
1996 |
Davies GJ, Tolley SP, Henrissat B, Hjort C, Schülein M. Structures of oligosaccharide-bound forms of the endoglucanase V from Humicola insolens at 1.9 A resolution. Biochemistry. 34: 16210-20. PMID 8519779 DOI: 10.1021/Bi00049A037 |
0.47 |
|
1996 |
Davies G, Sulzenbacher G, Henrissat B, Driguez H, Schülein M. Structural studies on cellulase–oligosaccharide complexes Acta Crystallographica Section a Foundations of Crystallography. 52: C192-C193. DOI: 10.1107/S0108767396091623 |
0.302 |
|
1995 |
Ducros V, Czjzek M, Belaich A, Gaudin C, Fierobe HP, Belaich JP, Davies GJ, Haser R. Crystal structure of the catalytic domain of a bacterial cellulase belonging to family 5. Structure (London, England : 1993). 3: 939-49. PMID 8535787 DOI: 10.1016/S0969-2126(01)00228-3 |
0.412 |
|
1995 |
Smith CK, Davies GJ, Dodson EJ, Moore MH. DNA-nogalamycin interactions: the crystal structure of d(TGATCA) complexed with nogalamycin. Biochemistry. 34: 415-25. PMID 7819233 DOI: 10.1021/Bi00002A005 |
0.31 |
|
1995 |
Henrissat B, Callebaut I, Fabrega S, Lehn P, Mornon J, Davies G. Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases Proceedings of the National Academy of Sciences of the United States of America. 92: 7090-7094. PMID 7624375 DOI: 10.1073/Pnas.92.15.7090 |
0.429 |
|
1995 |
Davies GJ, Schülein M. Structural studies on fungal endoglucanases from Humicola insolens Progress in Biotechnology. 10: 225-237. DOI: 10.1016/S0921-0423(06)80106-1 |
0.5 |
|
1994 |
Tyrrell R, Davies GJ, Wilson KS, Wilkinson AJ. Crystallization of a DNA and N-acetylserine binding fragment (residues 1 to 233) of Klebsiella aerogenes CysB protein, a member of the LysR family Journal of Molecular Biology. 235: 1159-1161. PMID 8289319 DOI: 10.1006/Jmbi.1994.1069 |
0.319 |
|
1994 |
Tolley S, Davies G, Hubbard RE, Smith DJ, Proudfoot AE, Payton MA, Cleasby A, Wonacott A, Wells TN. Crystallization and preliminary X-ray analysis of Candida albicans phosphomannose isomerase. Journal of Molecular Biology. 237: 349-50. PMID 8145246 DOI: 10.1006/Jmbi.1994.1235 |
0.328 |
|
1993 |
Davies GJ, Gamblin SJ, Littlechild JA, Watson HC. The structure of a thermally stable 3-phosphoglycerate kinase and a comparison with its mesophilic equivalent. Proteins. 15: 283-9. PMID 8456097 DOI: 10.1002/Prot.340150306 |
0.415 |
|
1993 |
Davies GJ, Dodson GG, Hubbard RE, Tolley SP, Dauter Z, Wilson KS, Hjort C, Mikkelsen JM, Rasmussen G, Schülein M. Structure and function of endoglucanase V Nature. 365: 362-364. PMID 8377830 DOI: 10.1038/365362A0 |
0.452 |
|
1992 |
Davies GJ, Littlechild JA, Watson HC, Hall L. Sequence and expression of the gene encoding 3-phosphoglycerate kinase from Bacillus stearothermophilus. Gene. 109: 39-45. PMID 1756980 DOI: 10.1016/0378-1119(91)90586-Z |
0.319 |
|
1991 |
Gamblin SJ, Davies GJ, Grimes JM, Jackson RM, Littlechild JA, Watson HC. Activity and specificity of human aldolases. Journal of Molecular Biology. 219: 573-6. PMID 2056525 DOI: 10.1016/0022-2836(91)90650-U |
0.392 |
|
1991 |
Wigley DB, Davies GJ, Dodson EJ, Maxwell A, Dodson G. Crystal structure of an N-terminal fragment of the DNA gyrase B protein. Nature. 351: 624-9. PMID 1646964 DOI: 10.1038/351624A0 |
0.304 |
|
1990 |
Gamblin SJ, Cooper B, Millar JR, Davies GJ, Littlechild JA, Watson HC. The crystal structure of human muscle aldolase at 3.0 A resolution. Febs Letters. 262: 282-6. PMID 2335208 DOI: 10.1016/0014-5793(90)80211-Z |
0.323 |
|
1987 |
Littlechild J, Davies G, Gamblin S, Watson H. Phosphoglycerate kinase from the extreme thermophile Thermus thermophilus
Crystallization and preliminary X-ray data Febs Letters. 225: 123-126. DOI: 10.1016/0014-5793(87)81143-2 |
0.341 |
|
Show low-probability matches. |