Qiuji Ye - Publications

Affiliations: 
Florida Institute of Technology, Melbourne, FL, United States 
Area:
Organic Synthesis, Medicinal Chemistry

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Chourey S, Wang R, Ye Q, Reddy CN, Sun S, Takenaka N, Powell WS, Rokach J. Concise Syntheses of Microsomal Metabolites of a Potent OXE (Oxoeicosanoid) Receptor Antagonist. Chemical & Pharmaceutical Bulletin. 71: 534-544. PMID 37394602 DOI: 10.1248/cpb.c22-00926  0.598
2022 Nicolaou KC, Pan S, Shelke Y, Rigol S, Bao R, Das D, Ye Q. A unified strategy for the total syntheses of eribulin and a macrolactam analogue of halichondrin B. Proceedings of the National Academy of Sciences of the United States of America. 119: e2208938119. PMID 35930662 DOI: 10.1073/pnas.2208938119  0.748
2022 Cossette C, Chourey S, Ye Q, Reddy CN, Wang R, Poulet S, Slobodchikova I, Vuckovic D, Rokach J, Powell WS. Metabolism of anti-inflammatory OXE (oxoeicosanoid) receptor antagonists by nonhuman primates. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 106144. PMID 35158054 DOI: 10.1016/j.ejps.2022.106144  0.556
2021 Nicolaou KC, Pan S, Shelke Y, Ye Q, Das D, Rigol S. A Highly Convergent Total Synthesis of Norhalichondrin B. Journal of the American Chemical Society. PMID 34851106 DOI: 10.1021/jacs.1c10539  0.757
2021 Cossette C, Miller LA, Ye Q, Chourey S, Reddy CN, Rokach J, Powell WS. Targeting the oxoeicosanoid (OXE) receptor with a selective antagonist inhibits allergen-induced pulmonary inflammation in non-human primates. British Journal of Pharmacology. PMID 34766334 DOI: 10.1111/bph.15721  0.56
2021 Nicolaou KC, Pan S, Shelke Y, Das D, Ye Q, Lu Y, Sau S, Bao R, Rigol S. A Reverse Approach to the Total Synthesis of Halichondrin B. Journal of the American Chemical Society. PMID 34105959 DOI: 10.1021/jacs.1c05270  0.745
2021 Nicolaou KC, Pan S, Pulukuri KK, Ye Q, Rigol S, Erande RD, Vourloumis D, Nocek BP, Munneke S, Lyssikatos J, Valdiosera A, Gu C, Lin B, Sarvaiaya H, Trinidad J, et al. Design, Synthesis, and Biological Evaluation of Tubulysin Analogues, Linker-Drugs, and Antibody-Drug Conjugates, Insights into Structure-Activity Relationships, and Tubulysin-Tubulin Binding Derived from X-ray Crystallographic Analysis. The Journal of Organic Chemistry. PMID 33544599 DOI: 10.1021/acs.joc.0c02755  0.706
2019 Ye Q, Chourey S, Reddy CN, Wang R, Cossette C, Gravel S, Slobodchikova I, Vuckovic D, Rokach J, Powell WS. Novel highly potent OXE receptor antagonists with prolonged plasma lifetimes that are converted to active metabolites in vivo in monkeys. British Journal of Pharmacology. PMID 31655025 DOI: 10.1111/Bph.14874  0.626
2019 Miller LA, Cossette C, Chourey S, Ye Q, Reddy CN, Rokach J, Powell WS. Inhibition of allergen-induced dermal eosinophilia by an oxoeicosanoid (OXE) receptor antagonist in nonhuman primates. British Journal of Pharmacology. PMID 31655023 DOI: 10.1111/Bph.14872  0.568
2018 Chourey S, Ye Q, Reddy CN, Wang R, Cossette C, Gravel S, Slobodchikova I, Vuckovic D, Rokach J, Powell WS. Novel highly potent and metabolically resistant oxoeicosanoid (OXE) receptor antagonists that block the actions of the granulocyte chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE). Journal of Medicinal Chemistry. PMID 29972644 DOI: 10.1021/Acs.Jmedchem.8B00154  0.635
2018 Chourey S, Ye Q, Reddy CN, Cossette C, Gravel S, Zeller M, Slobodchikova I, Vuckovic D, Rokach J, Powell WS. Corrigendum to "In vivo α-hydroxylation of a 2-alkylindole antagonist of the OXE receptor for the eosinophil chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid in monkeys" [Biochem. Pharmacol. 138 (2017) 107-118]. Biochemical Pharmacology. 154: 174. PMID 29754018 DOI: 10.1016/J.Bcp.2018.04.025  0.584
2018 Reddy CN, Alhamza H, Chourey S, Ye Q, Gore V, Cossette C, Gravel S, Slobodchikova I, Vuckovic D, Rokach J, Powell WS. Metabolism and pharmacokinetics of a potent N-acylindole antagonist of the OXE receptor for the eosinophil chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) in rats and monkeys. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 29339225 DOI: 10.1016/J.Ejps.2018.01.021  0.736
2017 Ye Q, Chourey S, Wang R, Chintam NR, Gravel S, Powell WS, Rokach J. Structure-activity relationship study of β-oxidation resistant indole-based 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) receptor antagonists. Bioorganic & Medicinal Chemistry Letters. PMID 28943042 DOI: 10.1016/J.Bmcl.2017.08.034  0.639
2017 Chourey S, Ye Q, Reddy CN, Cossette C, Gravel S, Zeller M, Slobodchikova I, Vuckovic D, Rokach J, Powell WS. In vivo α-hydroxylation of a 2-alkylindole antagonist of the OXE receptor for the eosinophil chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid in monkeys. Biochemical Pharmacology. PMID 28476332 DOI: 10.1016/J.Bcp.2017.04.031  0.608
2017 Nagendra Reddy C, Ye Q, Patel P, Sivendran S, Chourey S, Wang R, Anumolu JR, Grant GE, Powell WS, Rokach J. Design and synthesis of affinity chromatography ligands for the purification of 5-hydroxyeicosanoid dehydrogenase. Bioorganic & Medicinal Chemistry. 25: 116-125. PMID 28340986 DOI: 10.1016/J.Bmc.2016.10.017  0.762
2016 Cossette C, Chourey S, Ye Q, Nagendra Reddy C, Gore V, Gravel S, Slobodchikova I, Vuckovic D, Rokach J, Powell WS. Pharmacokinetics and metabolism of selective oxoeicosanoid (OXE) receptor antagonists and their effects on 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE)-induced granulocyte activation in monkeys. Journal of Medicinal Chemistry. PMID 27766872 DOI: 10.1021/Acs.Jmedchem.6B00895  0.751
2015 Cossette C, Gravel S, Reddy CN, Gore V, Chourey S, Ye Q, Snyder NW, Mesaros CA, Blair IA, Lavoie JP, Reinero CR, Rokach J, Powell WS. Biosynthesis and actions of 5-oxoeicosatetraenoic acid (5-oxo-ETE) on feline granulocytes. Biochemical Pharmacology. 96: 247-55. PMID 26032638 DOI: 10.1016/J.Bcp.2015.05.009  0.727
2015 Nagendra Reddy C, Ye Q, Chourey S, Gravel S, Powell WS, Rokach J. Stereoselective synthesis of two highly potent 5-oxo-ETE receptor antagonists Tetrahedron Letters. 56: 6896-6899. DOI: 10.1016/J.Tetlet.2015.10.097  0.628
2014 Patel P, Reddy CN, Gore V, Chourey S, Ye Q, Ouedraogo YP, Gravel S, Powell WS, Rokach J. Two Potent OXE-R Antagonists: Assignment of Stereochemistry. Acs Medicinal Chemistry Letters. 5: 815-9. PMID 25050171 DOI: 10.1021/Ml500161V  0.773
2014 Gore V, Chourey S, Ye Q, Patel P, Ouedraogo Y, Gravel S, Powell WS, Rokach J. Base-dependent formation of cis and trans olefins and their application in the synthesis of 5-oxo-ETE receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 24: 3385-8. PMID 24948567 DOI: 10.1016/J.Bmcl.2014.05.090  0.748
2014 Gore V, Gravel S, Cossette C, Patel P, Chourey S, Ye Q, Rokach J, Powell WS. Inhibition of 5-oxo-6,8,11,14-eicosatetraenoic acid-induced activation of neutrophils and eosinophils by novel indole OXE receptor antagonists. Journal of Medicinal Chemistry. 57: 364-77. PMID 24351031 DOI: 10.1021/Jm401292M  0.765
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