| Year |
Citation |
Score |
| 2023 |
Hudson L, Mason JW, Westphal MV, Richter MJR, Thielman JR, Hua BK, Gerry CJ, Xia G, Osswald HL, Knapp JM, Tan ZY, Kokkonda P, Tresco BIC, Liu S, Reidenbach AG, et al. Author Correction: Diversity-oriented synthesis encoded by deoxyoligonucleotides. Nature Communications. 14: 7589. PMID 37989745 DOI: 10.1038/s41467-023-43518-2 |
0.62 |
|
| 2023 |
Hudson L, Mason JW, Westphal MV, Richter MJR, Thielman JR, Hua BK, Gerry CJ, Xia G, Osswald HL, Knapp JM, Tan ZY, Kokkonda P, Tresco BIC, Liu S, Reidenbach AG, et al. Diversity-oriented synthesis encoded by deoxyoligonucleotides. Nature Communications. 14: 4930. PMID 37582753 DOI: 10.1038/s41467-023-40575-5 |
0.635 |
|
| 2020 |
Ghosh AK, Kovela S, Osswald HL, Amano M, Aoki M, Agniswamy J, Wang YF, Weber IT, Mitsuya H. Structure-Based Design of Highly Potent HIV-1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X-ray Structural Studies. Journal of Medicinal Chemistry. PMID 32348139 DOI: 10.1021/Acs.Jmedchem.0C00202 |
0.793 |
|
| 2019 |
Shang M, Feu KS, Vantourout JC, Barton LM, Osswald HL, Kato N, Gagaring K, McNamara CW, Chen G, Hu L, Ni S, Fernández-Canelas P, Chen M, Merchant RR, Qin T, et al. Modular, stereocontrolled C-H/C-C activation of alkyl carboxylic acids. Proceedings of the National Academy of Sciences of the United States of America. PMID 30996125 DOI: 10.1073/Pnas.1903048116 |
0.485 |
|
| 2018 |
Ghosh AK, Jadhav RD, Simpson H, Kovela S, Osswald H, Agniswamy J, Wang YF, Hattori SI, Weber IT, Mitsuya H. Design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors incorporating aminothiochromane and aminotetrahydronaphthalene carboxamide derivatives as the P2 ligands. European Journal of Medicinal Chemistry. 160: 171-182. PMID 30340140 DOI: 10.2210/Pdb6Dv4/Pdb |
0.786 |
|
| 2018 |
Ghosh AK, R Nyalapatla P, Kovela S, Rao KV, Brindisi M, Osswald HL, Amano M, Aoki M, Agniswamy J, Wang YF, Weber IT, Mitsuya H. Design and Synthesis of Highly Potent HIV-1 Protease Inhibitors Containing Tricyclic Fused Ring Systems as Novel P2 Ligands: Structure-Activity Studies, Biological and X-ray Structural Analysis. Journal of Medicinal Chemistry. PMID 29763303 DOI: 10.1021/Acs.Jmedchem.8B00298 |
0.794 |
|
| 2018 |
Ghosh AK, Rao KV, Nyalapatla PR, Kovela S, Brindisi M, Osswald HL, Sekhara Reddy B, Agniswamy J, Wang YF, Aoki M, Hattori SI, Weber IT, Mitsuya H. Design of Highly Potent, Dual Acting and Central Nervous System Penetrating HIV-1 Protease Inhibitors with Excellent Potency against Multidrug-Resistant HIV-1 Variants. Chemmedchem. PMID 29437300 DOI: 10.1002/Cmdc.201700824 |
0.787 |
|
| 2018 |
Ghosh AK, Rao KV, Nyalapatla PR, Kovela S, Brindisi M, Osswald HL, Sekhara Reddy B, Agniswamy J, Wang Y, Aoki M, Hattori S, Weber IT, Mitsuya H. Front Cover: Design of Highly Potent, Dual-Acting and Central-Nervous-System-Penetrating HIV-1 Protease Inhibitors with Excellent Potency against Multidrug-Resistant HIV-1 Variants (ChemMedChem 8/2018) Chemmedchem. 13: 762-762. DOI: 10.1002/Cmdc.201800226 |
0.586 |
|
| 2017 |
Aoki M, Hayashi H, Rao KV, Das D, Higashi-Kuwata N, Bulut H, Aoki-Ogata H, Takamatsu Y, Yedidi RS, Davis DA, Hattori SI, Nishida N, Hasegawa K, Takamune N, Nyalapatla PR, ... Osswald HL, et al. A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency. Elife. 6. PMID 29039736 DOI: 10.7554/Elife.28020 |
0.581 |
|
| 2017 |
Ghosh AK, Rao KV, Nyalapatla PR, Osswald HL, Martyr CD, Aoki M, Hayashi H, Agniswamy J, Wang YF, Bulut H, Das D, Weber IT, Mitsuya H. Design and Development of Highly Potent HIV-1 Protease Inhibitors with a Crown-Like Oxotricyclic Core as the P2-Ligand To Combat Multidrug-Resistant HIV Variants. Journal of Medicinal Chemistry. PMID 28418652 DOI: 10.1021/Acs.Jmedchem.7B00172 |
0.664 |
|
| 2016 |
Ghosh AK, Osswald HL, Glauninger K, Agniswamy J, Wang YF, Hayashi H, Aoki M, Weber IT, Mitsuya H. Probing Lipophilic Adamantyl Group as the P1-Ligand for HIV-1 Protease Inhibitors: Design, Synthesis, Protein X-ray Structural Studies, and Biological Evaluation. Journal of Medicinal Chemistry. PMID 27389367 DOI: 10.1021/Acs.Jmedchem.6B00639 |
0.643 |
|
| 2016 |
Ghosh AK, Osswald HL, Prato G. Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS. Journal of Medicinal Chemistry. PMID 26799988 DOI: 10.1021/Acs.Jmedchem.5B01697 |
0.571 |
|
| 2015 |
St John SE, Therkelsen MD, Nyalapatla PR, Osswald HL, Ghosh AK, Mesecar AD. X-ray structure and inhibition of the feline infectious peritonitis virus 3C-like protease: Structural implications for drug design. Bioorganic & Medicinal Chemistry Letters. 25: 5072-7. PMID 26592814 DOI: 10.1016/J.Bmcl.2015.10.023 |
0.523 |
|
| 2015 |
Ghosh AK, Martyr CD, Osswald HL, Sheri VR, Kassekert LA, Chen S, Agniswamy J, Wang YF, Hayashi H, Aoki M, Weber IT, Mitsuya H. Design of HIV-1 Protease Inhibitors with Amino-bis-tetrahydrofuran Derivatives as P2-Ligands to Enhance Backbone-Binding Interactions: Synthesis, Biological Evaluation, and Protein-Ligand X-ray Studies. Journal of Medicinal Chemistry. PMID 26306007 DOI: 10.1021/Acs.Jmedchem.5B00900 |
0.635 |
|
| 2015 |
Ghosh AK, Xu CX, Osswald HL. Enantioselective Synthesis of Dioxatriquinane Structural Motifs for HIV-1 Protease Inhibitors Using a Cascade Radical Cyclization. Tetrahedron Letters. 56: 3314-3317. PMID 26185337 DOI: 10.1016/J.Tetlet.2015.01.019 |
0.633 |
|
| 2015 |
Ghosh AK, Yu X, Osswald HL, Agniswamy J, Wang YF, Amano M, Weber IT, Mitsuya H. Structure-Based Design of Potent HIV-1 Protease Inhibitors with Modified P1-Biphenyl Ligands: Synthesis, Biological Evaluation, and Enzyme-Inhibitor X-ray Structural Studies. Journal of Medicinal Chemistry. PMID 26107245 DOI: 10.1021/Acs.Jmedchem.5B00676 |
0.667 |
|
| 2015 |
Tomar S, Johnston ML, St John SE, Osswald HL, Nyalapatla PR, Paul LN, Ghosh AK, Denison MR, Mesecar AD. Ligand-induced dimerization of MERS coronavirus nsp5 protease (3CLpro): implications for nsp5 regulation and the development of antivirals. The Journal of Biological Chemistry. PMID 26055715 DOI: 10.1074/Jbc.M115.651463 |
0.513 |
|
| 2014 |
Deng X, StJohn SE, Osswald HL, O'Brien A, Banach BS, Sleeman K, Ghosh AK, Mesecar AD, Baker SC. Coronaviruses resistant to a 3C-like protease inhibitor are attenuated for replication and pathogenesis, revealing a low genetic barrier but high fitness cost of resistance. Journal of Virology. 88: 11886-98. PMID 25100843 DOI: 10.1128/Jvi.01528-14 |
0.484 |
|
| 2014 |
Ghosh AK, Schiltz GE, Rusere LN, Osswald HL, Walters DE, Amano M, Mitsuya H. Design and synthesis of potent macrocyclic HIV-1 protease inhibitors involving P1-P2 ligands. Organic & Biomolecular Chemistry. 12: 6842-54. PMID 25050776 DOI: 10.1039/C4Ob00738G |
0.624 |
|
| 2014 |
Ghosh AK, Osswald HL. BACE1 (β-secretase) inhibitors for the treatment of Alzheimer's disease. Chemical Society Reviews. 43: 6765-813. PMID 24691405 DOI: 10.1039/C3Cs60460H |
0.485 |
|
| 2014 |
Agnihothram S, Yount BL, Donaldson EF, Huynh J, Menachery VD, Gralinski LE, Graham RL, Becker MM, Tomar S, Scobey TD, Osswald HL, Whitmore A, Gopal R, Ghosh AK, Mesecar A, et al. A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant. Mbio. 5: e00047-14. PMID 24667706 DOI: 10.1128/Mbio.00047-14 |
0.432 |
|
| 2014 |
Ghosh AK, Xu CX, Osswald HL. Enantioselective synthesis of dioxatriquinane structural motifs for HIV-1 protease inhibitors using a cascade radical cyclization Tetrahedron Letters. DOI: 10.1016/j.tetlet.2015.01.019 |
0.576 |
|
| 2013 |
Ghosh AK, Parham GL, Martyr CD, Nyalapatla PR, Osswald HL, Agniswamy J, Wang YF, Amano M, Weber IT, Mitsuya H. Highly potent HIV-1 protease inhibitors with novel tricyclic P2 ligands: design, synthesis, and protein-ligand X-ray studies. Journal of Medicinal Chemistry. 56: 6792-802. PMID 23947685 DOI: 10.1021/Jm400768F |
0.639 |
|
| Show low-probability matches. |