Jacopo Meldolesi, PhD - Publications

Affiliations: 
Unit of Molecular and Cellular Neuroscience Vita-Salute San Raffaele University, Milan, Italy, Milano, Lombardia, Italy 
Area:
exocytosis

233 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Meldolesi J. Unconventional Protein Secretion Dependent on Two Extracellular Vesicles: Exosomes and Ectosomes. Frontiers in Cell and Developmental Biology. 10: 877344. PMID 35756998 DOI: 10.3389/fcell.2022.877344  0.327
2020 Meldolesi J. Alternative Splicing by NOVA Factors: From Gene Expression to Cell Physiology and Pathology. International Journal of Molecular Sciences. 21. PMID 32486302 DOI: 10.3390/Ijms21113941  0.326
2019 D'Alessandro R, Meldolesi J. News about non-secretory exocytosis: mechanisms, properties, and functions. Journal of Molecular Cell Biology. PMID 30605539 DOI: 10.1093/Jmcb/Mjy084  0.418
2018 Meldolesi J. Exosomes and Ectosomes in Intercellular Communication. Current Biology : Cb. 28: R435-R444. PMID 29689228 DOI: 10.1016/J.Cub.2018.01.059  0.448
2016 Valtorta F, Benfenati F, Zara F, Meldolesi J. PRRT2: from Paroxysmal Disorders to Regulation of Synaptic Function. Trends in Neurosciences. PMID 27624551 DOI: 10.1016/J.Tins.2016.08.005  0.338
2016 Prada I, Meldolesi J. Binding and Fusion of Extracellular Vesicles to the Plasma Membrane of Their Cell Targets. International Journal of Molecular Sciences. 17. PMID 27517914 DOI: 10.3390/Ijms17081296  0.426
2015 Garcia-Manteiga JM, Bonfiglio S, Folladori L, Malosio ML, Lazarevic D, Stupka E, Cittaro D, Meldolesi J. REST-Governed Gene Expression Profiling in a Neuronal Cell Model Reveals Novel Direct and Indirect Processes of Repression and Up-Regulation. Frontiers in Cellular Neuroscience. 9: 438. PMID 26617488 DOI: 10.3389/Fncel.2015.00438  0.323
2015 Meldolesi J. Pharmacology of the cell/matrix form of adhesion. Pharmacological Research. PMID 26521758 DOI: 10.1016/J.Phrs.2015.10.019  0.354
2015 Colombo F, Meldolesi J. L1-CAM and N-CAM: From Adhesion Proteins to Pharmacological Targets. Trends in Pharmacological Sciences. 36: 769-81. PMID 26478212 DOI: 10.1016/J.Tips.2015.08.004  0.331
2015 Garcia-Manteiga JM, Bonfiglio S, Malosio ML, Lazarevic D, Stupka E, Cittaro D, Meldolesi J. Epigenomics of Neural Cells: REST-Induced Down- and Upregulation of Gene Expression in a Two-Clone PC12 Cell Model. Biomed Research International. 2015: 202914. PMID 26413508 DOI: 10.1155/2015/202914  0.331
2015 Cocucci E, Meldolesi J. Ectosomes and exosomes: shedding the confusion between extracellular vesicles. Trends in Cell Biology. 25: 364-72. PMID 25683921 DOI: 10.1016/J.Tcb.2015.01.004  0.709
2015 Colombo F, Meldolesi J. New mechanisms of neurite outgrowth and TrkA receptor activation/signaling Receptors and Clinical Investigation. 2. DOI: 10.14800/Rci.542  0.316
2014 Colombo F, Racchetti G, Meldolesi J. Neurite outgrowth induced by NGF or L1CAM via activation of the TrkA receptor is sustained also by the exocytosis of enlargeosomes. Proceedings of the National Academy of Sciences of the United States of America. 111: 16943-8. PMID 25385598 DOI: 10.1073/Pnas.1406097111  0.404
2013 Negrini S, D'Alessandro R, Meldolesi J. NGF signaling in PC12 cells: the cooperation of p75(NTR) with TrkA is needed for the activation of both mTORC2 and the PI3K signalling cascade. Biology Open. 2: 855-66. PMID 23951412 DOI: 10.1242/Bio.20135116  0.328
2013 D'Alessandro R, Meldolesi J. Expression and function of the dense-core vesicle membranes are governed by the transcription repressor REST. Febs Letters. 587: 1915-22. PMID 23651552 DOI: 10.1016/J.Febslet.2013.04.024  0.429
2013 Tagliavacca L, Colombo F, Racchetti G, Meldolesi J. L1CAM and its cell-surface mutants: new mechanisms and effects relevant to the physiology and pathology of neural cells. Journal of Neurochemistry. 124: 397-409. PMID 22973895 DOI: 10.1111/Jnc.12015  0.343
2012 de Curtis I, Meldolesi J. Cell surface dynamics - how Rho GTPases orchestrate the interplay between the plasma membrane and the cortical cytoskeleton. Journal of Cell Science. 125: 4435-44. PMID 23093576 DOI: 10.1242/Jcs.108266  0.399
2012 Mikulak J, Negrini S, Klajn A, D'Alessandro R, Mavilio D, Meldolesi J. Dual REST-dependence of L1CAM: from gene expression to alternative splicing governed by Nova2 in neural cells. Journal of Neurochemistry. 120: 699-709. PMID 22176577 DOI: 10.1111/J.1471-4159.2011.07626.X  0.345
2012 Racchetti G, D'Alessandro R, Meldolesi J. Astrocyte stellation, a process dependent on Rac1 is sustained by the regulated exocytosis of enlargeosomes. Glia. 60: 465-75. PMID 22144092 DOI: 10.1002/Glia.22280  0.354
2012 Cocucci E, Meldolesi J. Errarum: Ectosomes (Current Biology (2011) 21 (R940-R941)) Current Biology. 22: 1359. DOI: 10.1016/J.Cub.2012.07.014  0.619
2011 Cocucci E, Cocucci E, Meldolesi J. Ectosomes. Current Biology : Cb. 21: R940-1. PMID 22153157 DOI: 10.1016/j.cub.2011.10.011  0.6
2011 Tomasoni R, Negrini S, Fiordaliso S, Klajn A, Tkatch T, Mondino A, Meldolesi J, D'Alessandro R. A signaling loop of REST, TSC2 and β-catenin governs proliferation and function of PC12 neural cells. Journal of Cell Science. 124: 3174-86. PMID 21868364 DOI: 10.1242/Jcs.087551  0.318
2011 Giorgi C, Romagnoli A, Agnoletto C, Bergamelli L, Sorrentino G, Brini M, Pozzan T, Meldolesi J, Pinton P, Rizzuto R. Translocation of signalling proteins to the plasma membrane revealed by a new bioluminescent procedure. Bmc Cell Biology. 12: 27. PMID 21658234 DOI: 10.1186/1471-2121-12-27  0.429
2011 Meldolesi J. Neurite outgrowth: this process, first discovered by Santiago Ramon y Cajal, is sustained by the exocytosis of two distinct types of vesicles. Brain Research Reviews. 66: 246-55. PMID 20600308 DOI: 10.1016/J.Brainresrev.2010.06.004  0.358
2010 D'Alessandro R, Racchetti G, Meldolesi J. Outgrowth of neurites is a dual process. Communicative & Integrative Biology. 3: 576-8. PMID 21331244 DOI: 10.4161/Cib.3.6.13093  0.407
2010 D'Alessandro R, Meldolesi J. In PC12 cells, expression of neurosecretion and neurite outgrowth are governed by the transcription repressor REST/NRSF. Cellular and Molecular Neurobiology. 30: 1295-302. PMID 21046448 DOI: 10.1007/S10571-010-9602-0  0.394
2010 Schulte C, Racchetti G, D'Alessandro R, Meldolesi J. A new form of neurite outgrowth sustained by the exocytosis of enlargeosomes expressed under the control of REST. Traffic (Copenhagen, Denmark). 11: 1304-14. PMID 20604903 DOI: 10.1111/J.1600-0854.2010.01095.X  0.351
2010 Bellani S, Sousa VL, Ronzitti G, Valtorta F, Meldolesi J, Chieregatti E. The regulation of synaptic function by alpha-synuclein. Communicative & Integrative Biology. 3: 106-9. PMID 20585500 DOI: 10.4161/Cib.3.2.10964  0.31
2010 Ariano P, Zamburlin P, D'Alessandro R, Meldolesi J, Lovisolo D. Differential repression by the transcription factor REST/NRSF of the various Ca2+ signalling mechanisms in pheochromocytoma PC12 cells. Cell Calcium. 47: 360-8. PMID 20171735 DOI: 10.1016/J.Ceca.2010.01.007  0.448
2010 Racchetti G, Lorusso A, Schulte C, Gavello D, Carabelli V, D'Alessandro R, Meldolesi J. Rapid neurite outgrowth in neurosecretory cells and neurons is sustained by the exocytosis of a cytoplasmic organelle, the enlargeosome. Journal of Cell Science. 123: 165-70. PMID 20026640 DOI: 10.1242/Jcs.059634  0.389
2009 Stefano L, Racchetti G, Bianco F, Passini N, Gupta RS, Panina Bordignon P, Meldolesi J. The surface-exposed chaperone, Hsp60, is an agonist of the microglial TREM2 receptor. Journal of Neurochemistry. 110: 284-94. PMID 19457124 DOI: 10.1111/J.1471-4159.2009.06130.X  0.374
2009 Klajn A, Ferrai C, Stucchi L, Prada I, Podini P, Baba T, Rocchi M, Meldolesi J, D'Alessandro R. The rest repression of the neurosecretory phenotype is negatively modulated by BHC80, a protein of the BRAF/HDAC complex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6296-307. PMID 19439607 DOI: 10.1523/Jneurosci.5943-08.2009  0.314
2009 D'Alessandro R, Klajn A, Meldolesi J. Expression of dense-core vesicles and of their exocytosis are governed by the repressive transcription factor NRSF/REST. Annals of the New York Academy of Sciences. 1152: 194-200. PMID 19161390 DOI: 10.1111/J.1749-6632.2008.03988.X  0.407
2009 Cocucci E, Racchetti G, Meldolesi J. Shedding microvesicles: artefacts no more. Trends in Cell Biology. 19: 43-51. PMID 19144520 DOI: 10.1016/J.Tcb.2008.11.003  0.715
2008 Cocucci E, Racchetti G, Rupnik M, Meldolesi J. The regulated exocytosis of enlargeosomes is mediated by a SNARE machinery that includes VAMP4. Journal of Cell Science. 121: 2983-91. PMID 18713833 DOI: 10.1242/Jcs.032029  0.706
2008 Meldolesi J. Inhibition of adipogenesis: a new job for the ER Ca2+ pool. The Journal of Cell Biology. 182: 11-3. PMID 18606853 DOI: 10.1083/Jcb.200805110  0.412
2008 D'Alessandro R, Klajn A, Stucchi L, Podini P, Malosio ML, Meldolesi J. Expression of the neurosecretory process in PC12 cells is governed by REST. Journal of Neurochemistry. 105: 1369-83. PMID 18298477 DOI: 10.1111/J.1471-4159.2008.05259.X  0.376
2007 Prada I, Cocucci E, Racchetti G, Meldolesi J. The Ca2+-dependent exocytosis of enlargeosomes is greatly reinforced by genistein via a non-tyrosine kinase-dependent mechanism. Febs Letters. 581: 4932-6. PMID 17904556 DOI: 10.1016/J.Febslet.2007.09.026  0.702
2007 Cocucci E, Racchetti G, Podini P, Meldolesi J. Enlargeosome traffic: exocytosis triggered by various signals is followed by endocytosis, membrane shedding or both. Traffic (Copenhagen, Denmark). 8: 742-57. PMID 17488290 DOI: 10.1111/J.1600-0854.2007.00566.X  0.742
2006 Lorusso A, Covino C, Priori G, Bachi A, Meldolesi J, Chieregatti E. Annexin2 coating the surface of enlargeosomes is needed for their regulated exocytosis. The Embo Journal. 25: 5443-56. PMID 17082761 DOI: 10.1038/Sj.Emboj.7601419  0.483
2006 Falcone S, Cocucci E, Podini P, Kirchhausen T, Clementi E, Meldolesi J. Macropinocytosis: regulated coordination of endocytic and exocytic membrane traffic events. Journal of Cell Science. 119: 4758-69. PMID 17077125 DOI: 10.1242/Jcs.03238  0.797
2006 Prada I, Ongania GN, Buonsanti C, Panina-Bordignon P, Meldolesi J. Triggering receptor expressed in myeloid cells 2 (TREM2) trafficking in microglial cells: continuous shuttling to and from the plasma membrane regulated by cell stimulation. Neuroscience. 140: 1139-48. PMID 16675145 DOI: 10.1016/J.Neuroscience.2006.03.058  0.403
2006 Cocucci E, Lorusso A, Ongania GN, Klajn A, Meldolesi J. Non-secretory exocytoses in the brain. Journal of Physiology, Paris. 99: 140-5. PMID 16426824 DOI: 10.1016/J.Jphysparis.2005.12.081  0.726
2005 Sala C, Roussignol G, Meldolesi J, Fagni L. Key role of the postsynaptic density scaffold proteins Shank and Homer in the functional architecture of Ca2+ homeostasis at dendritic spines in hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4587-92. PMID 15872106 DOI: 10.1523/Jneurosci.4822-04.2005  0.45
2005 Chieregatti E, Meldolesi J. Regulated exocytosis: new organelles for non-secretory purposes. Nature Reviews. Molecular Cell Biology. 6: 181-7. PMID 15688003 DOI: 10.1038/Nrm1572  0.409
2004 Sessa G, Podini P, Mariani M, Meroni A, Spreafico R, Sinigaglia F, Colonna M, Panina P, Meldolesi J. Distribution and signaling of TREM2/DAP12, the receptor system mutated in human polycystic lipomembraneous osteodysplasia with sclerosing leukoencephalopathy dementia. The European Journal of Neuroscience. 20: 2617-28. PMID 15548205 DOI: 10.1111/J.1460-9568.2004.03729.X  0.397
2004 Cocucci E, Racchetti G, Podini P, Rupnik M, Meldolesi J. Enlargeosome, an exocytic vesicle resistant to nonionic detergents, undergoes endocytosis via a nonacidic route. Molecular Biology of the Cell. 15: 5356-68. PMID 15469985 DOI: 10.1091/Mbc.E04-07-0577  0.757
2004 Cerny J, Feng Y, Yu A, Miyake K, Borgonovo B, Klumperman J, Meldolesi J, McNeil PL, Kirchhausen T. The small chemical vacuolin-1 inhibits Ca(2+)-dependent lysosomal exocytosis but not cell resealing. Embo Reports. 5: 883-8. PMID 15332114 DOI: 10.1038/Sj.Embor.7400243  0.647
2004 Meldolesi J, Chieregatti E. Fusion has found its calcium sensor. Nature Cell Biology. 6: 476-8. PMID 15170455 DOI: 10.1038/Ncb0604-476  0.331
2004 Meldolesi J. The development of Ca2+ indicators: a breakthrough in pharmacological research. Trends in Pharmacological Sciences. 25: 172-4. PMID 15116718 DOI: 10.1016/J.Tips.2004.02.004  0.396
2004 Malosio ML, Giordano T, Laslop A, Meldolesi J. Dense-core granules: a specific hallmark of the neuronal/neurosecretory cell phenotype. Journal of Cell Science. 117: 743-9. PMID 14734658 DOI: 10.1242/Jcs.00934  0.385
2004 Meldolesi J, Chieregatti E, Luisa Malosio M. Requirements for the identification of dense-core granules. Trends in Cell Biology. 14: 13-9. PMID 14729176 DOI: 10.1016/J.Tcb.2003.11.006  0.337
2002 Borgonovo B, Cocucci E, Racchetti G, Podini P, Bachi A, Meldolesi J. Regulated exocytosis: a novel, widely expressed system. Nature Cell Biology. 4: 955-62. PMID 12447386 DOI: 10.1038/Ncb888  0.743
2002 Meldolesi J. Rapidly exchanging Ca(2+) stores: ubiquitous partners of surface channels in neurons. News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 17: 144-9. PMID 12136042 DOI: 10.1152/Nips.01385.2002  0.389
2002 Grundschober C, Malosio ML, Astolfi L, Giordano T, Nef P, Meldolesi J. Neurosecretion competence. A comprehensive gene expression program identified in PC12 cells. The Journal of Biological Chemistry. 277: 36715-24. PMID 12070162 DOI: 10.1074/Jbc.M203777200  0.307
2001 Gatti G, Trifari S, Mesaeli N, Parker JM, Michalak M, Meldolesi J. Head-to-tail oligomerization of calsequestrin: a novel mechanism for heterogeneous distribution of endoplasmic reticulum luminal proteins. The Journal of Cell Biology. 154: 525-34. PMID 11489915 DOI: 10.1083/Jcb.200103002  0.357
2001 Valtorta F, Meldolesi J, Fesce R. Synaptic vesicles: is kissing a matter of competence? Trends in Cell Biology. 11: 324-8. PMID 11489637 DOI: 10.1016/S0962-8924(01)02058-X  0.359
2001 Pezzati R, Meldolesi J, Grohovaz F. Ultra rapid calcium events in electrically stimulated frog nerve terminals. Biochemical and Biophysical Research Communications. 285: 724-7. PMID 11453653 DOI: 10.1006/Bbrc.2001.5241  0.335
2001 Bezzi P, Domercq M, Brambilla L, Galli R, Schols D, De Clercq E, Vescovi A, Bagetta G, Kollias G, Meldolesi J, Volterra A. CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity. Nature Neuroscience. 4: 702-10. PMID 11426226 DOI: 10.1038/89490  0.331
2001 Fesce R, Meldolesi J, Valtorta F. Regulation of kiss-and-run exocytosis: A switch or a maturation process? [2] Trends in Cell Biology. 11: 405. DOI: 10.1016/S0962-8924(01)02116-X  0.363
1999 Barsacchi R, Heider H, Girault J, Meldolesi J. Requirement of pyk2 for the activation of the MAP kinase cascade induced by Ca(2+) (but not by PKC or G protein) in PC12 cells. Febs Letters. 461: 273-6. PMID 10567710 DOI: 10.1016/S0014-5793(99)01468-4  0.398
1999 Fesce R, Meldolesi J. Peeping at the vesicle kiss. Nature Cell Biology. 1: E3-4. PMID 10559869 DOI: 10.1038/8950  0.355
1999 Malosio ML, Benfante R, Racchetti G, Borgonovo B, Rosa P, Meldolesi J. Neurosecretory cells without neurosecretion: evidence of an independently regulated trait of the cell phenotype. The Journal of Physiology. 520: 43-52. PMID 10517799 DOI: 10.1111/J.1469-7793.1999.T01-1-00043.X  0.377
1999 Rowe J, Corradi N, Malosio ML, Taverna E, Halban P, Meldolesi J, Rosa P. Blockade of membrane transport and disassembly of the Golgi complex by expression of syntaxin 1A in neurosecretion-incompetent cells: prevention by rbSEC1. Journal of Cell Science. 112: 1865-77. PMID 10341206  0.31
1999 Kasai H, Kishimoto T, Liu TT, Miyashita Y, Podini P, Grohovaz F, Meldolesi J. Multiple and diverse forms of regulated exocytosis in wild-type and defective PC12 cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 945-9. PMID 9927673 DOI: 10.1073/Pnas.96.3.945  0.42
1998 Borgonovo B, Racchetti G, Malosio M, Benfante R, Podini P, Rosa P, Meldolesi J. Neurosecretion competence, an independently regulated trait of the neurosecretory cell phenotype. The Journal of Biological Chemistry. 273: 34683-6. PMID 9856988 DOI: 10.1074/Jbc.273.52.34683  0.384
1998 Meldolesi J. Regulated exocytosis in neurons and neurosecretory cells: structural events and expression competence. Journal of Physiology, Paris. 92: 119-21. PMID 9782454 DOI: 10.1016/S0928-4257(98)80148-4  0.358
1998 Meldolesi J, Pozzan T. The heterogeneity of ER Ca2+ stores has a key role in nonmuscle cell signaling and function. The Journal of Cell Biology. 142: 1395-8. PMID 9744872 DOI: 10.1083/Jcb.142.6.1395  0.387
1998 Meldolesi J. Calcium signalling. Oscillation, activation, expression. Nature. 392: 863, 865-6. PMID 9582065 DOI: 10.1038/31804  0.383
1998 Meldolesi J, Pozzan T. The endoplasmic reticulum Ca2+ store: a view from the lumen. Trends in Biochemical Sciences. 23: 10-4. PMID 9478128 DOI: 10.1016/S0968-0004(97)01143-2  0.399
1997 Lièvremont JP, Rizzuto R, Hendershot L, Meldolesi J. BiP, a major chaperone protein of the endoplasmic reticulum lumen, plays a direct and important role in the storage of the rapidly exchanging pool of Ca2+. The Journal of Biological Chemistry. 272: 30873-9. PMID 9388233 DOI: 10.1074/Jbc.272.49.30873  0.337
1997 Sciorati C, Nisticò G, Meldolesi J, Clementi E. Nitric oxide effects on cell growth: GMP-dependent stimulation of the AP-1 transcription complex and cyclic GMP-independent slowing of cell cycling. British Journal of Pharmacology. 122: 687-97. PMID 9375965 DOI: 10.1038/Sj.Bjp.0701413  0.337
1997 Montero M, Alvarez J, Scheenen WJ, Rizzuto R, Meldolesi J, Pozzan T. Ca2+ homeostasis in the endoplasmic reticulum: coexistence of high and low [Ca2+] subcompartments in intact HeLa cells. The Journal of Cell Biology. 139: 601-11. PMID 9348278 DOI: 10.1083/Jcb.139.3.601  0.432
1997 Gatti G, Podini P, Meldolesi J. Overexpression of calsequestrin in L6 myoblasts: formation of endoplasmic reticulum subdomains and their evolution into discrete vacuoles where aggregates of the protein are specifically accumulated. Molecular Biology of the Cell. 8: 1789-803. PMID 9307974 DOI: 10.1091/Mbc.8.9.1789  0.384
1997 Pezzati R, Bossi M, Podini P, Meldolesi J, Grohovaz F. High-resolution calcium mapping of the endoplasmic reticulum-Golgi-exocytic membrane system. Electron energy loss imaging analysis of quick frozen-freeze dried PC12 cells. Molecular Biology of the Cell. 8: 1501-12. PMID 9285821 DOI: 10.1091/Mbc.8.8.1501  0.36
1997 Clementi E, Meldolesi J. The cross-talk between nitric oxide and Ca2+: a story with a complex past and a promising future. Trends in Pharmacological Sciences. 18: 266-9. PMID 9277129 DOI: 10.1016/S0165-6147(97)01087-0  0.315
1996 Rooney E, Meldolesi J. The endoplasmic reticulum in PC12 cells. Evidence for a mosaic of domains differently specialized in Ca2+ handling. The Journal of Biological Chemistry. 271: 29304-11. PMID 8910591 DOI: 10.1074/Jbc.271.46.29304  0.451
1996 Corradi N, Borgonovo B, Clementi E, Bassetti M, Racchetti G, Consalez GG, Huttner WB, Meldolesi J, Rosa P. Overall lack of regulated secretion in a PC12 variant cell clone. The Journal of Biological Chemistry. 271: 27116-24. PMID 8900203 DOI: 10.1074/Jbc.271.43.27116  0.42
1996 Clementi E, Racchetti G, Melino G, Meldolesi J. Cytosolic Ca2+ buffering, a cell property that in some neurons markedly decreases during aging, has a protective effect against NMDA/nitric oxide-induced excitotoxicity. Life Sciences. 59: 389-97. PMID 8761326 DOI: 10.1016/0024-3205(96)00317-7  0.387
1996 Fesce R, Valtorta F, Meldolesi J. The membrane fusion machine and neurotransmitter release. Neurochemistry International. 28: 15-21. PMID 8746760 DOI: 10.1016/0197-0186(95)00059-H  0.348
1996 Clementi E, Riccio M, Sciorati C, Nisticò G, Meldolesi J. The type 2 ryanodine receptor of neurosecretory PC12 cells is activated by cyclic ADP-ribose. Role of the nitric oxide/cGMP pathway. The Journal of Biological Chemistry. 271: 17739-45. PMID 8663443 DOI: 10.1074/Jbc.271.30.17739  0.449
1996 Codazzi F, Racchetti G, Grohovaz F, Meldolesi J. Transduction signals induced in rat brain cortex astrocytes by the HIV-1 gp120 glycoprotein. Febs Letters. 384: 135-7. PMID 8612809 DOI: 10.1016/0014-5793(96)00301-8  0.316
1995 Grierson JP, Meldolesi J. Shear stress-induced [Ca2+]i transients and oscillations in mouse fibroblasts are mediated by endogenously released ATP. The Journal of Biological Chemistry. 270: 4451-6. PMID 7876211 DOI: 10.1074/Jbc.270.9.4451  0.427
1995 Raichman M, Panzeri MC, Clementi E, Papazafiri P, Eckley M, Clegg DO, Villa A, Meldolesi J. Differential localization and functional role of calsequestrin in growing and differentiated myoblasts. The Journal of Cell Biology. 128: 341-54. PMID 7844148 DOI: 10.1083/Jcb.128.3.341  0.439
1995 Papazafiri P, Podini P, Meldolesi J, Yamaguchi T. Ageing affects cytosolic Ca2+ binding proteins and synaptic markers in the retina but not in cerebral cortex neurons of the rat. Neuroscience Letters. 186: 65-8. PMID 7783952 DOI: 10.1016/0304-3940(95)11285-5  0.346
1995 Clementi E, Martini A, Stefani G, Meldolesi J, Volpe P. LU52396, an inhibitor of the store-dependent (capacitative) Ca2+ influx. European Journal of Pharmacology. 289: 23-31. PMID 7781709 DOI: 10.1016/0922-4106(95)90164-7  0.444
1995 Lorenzon P, Zacchetti D, Codazzi F, Fumagalli G, Meldolesi J, Grohovaz F. Ca2+ waves in PC12 neurites: a bidirectional, receptor-oriented form of Ca2+ signaling. The Journal of Cell Biology. 129: 797-804. PMID 7730413 DOI: 10.1083/Jcb.129.3.797  0.431
1995 Clementi E, Sciorati C, Riccio M, Miloso M, Meldolesi J, Nisticò G. Nitric oxide action on growth factor-elicited signals. Phosphoinositide hydrolysis and [Ca2+]i responses are negatively modulated via a cGMP-dependent protein kinase I pathway. The Journal of Biological Chemistry. 270: 22277-82. PMID 7673208 DOI: 10.1074/Jbc.270.38.22277  0.432
1995 Grierson JP, Meldolesi J. Calcium homeostasis in mouse fibroblast cells: affected by U-73122, a putative phospholipase C beta blocker, via multiple mechanisms. British Journal of Pharmacology. 115: 11-4. PMID 7647965 DOI: 10.1111/J.1476-5381.1995.Tb16312.X  0.442
1995 Bastianutto C, Clementi E, Codazzi F, Podini P, De Giorgi F, Rizzuto R, Meldolesi J, Pozzan T. Overexpression of calreticulin increases the Ca2+ capacity of rapidly exchanging Ca2+ stores and reveals aspects of their lumenal microenvironment and function. The Journal of Cell Biology. 130: 847-55. PMID 7642702 DOI: 10.1083/jcb.130.4.847  0.313
1995 Codazzi F, Menegon A, Zacchetti D, Ciardo A, Grohovaz F, Meldolesi J. HIV-1 gp120 glycoprotein induces [Ca2+]i responses not only in type-2 but also type-1 astrocytes and oligodendrocytes of the rat cerebellum. The European Journal of Neuroscience. 7: 1333-41. PMID 7582107 DOI: 10.1111/J.1460-9568.1995.Tb01124.X  0.392
1995 Codazzi F, Zacchetti D, Lorenzon P, Fumagalli G, Meldolesi J, Grohovaz F. [Ca2+]i redistribution patterns after activation of B2, M3 and P2Y2 receptors in NGF-differentiated PC12 cells Pharmacological Research. 31: 206. DOI: 10.1016/1043-6618(95)87084-9  0.361
1995 CLEMENTI E, SCIORATI C, MELDOLESI J, NISTICO G. Nitric oxide modulates Ca2+ release and influx elicited by activation of growth factor receptors Pharmacological Research. 31: 9-9. DOI: 10.1016/1043-6618(95)86297-8  0.36
1994 Fesce R, Grohovaz F, Valtorta F, Meldolesi J. Neurotransmitter release: fusion or 'kiss-and-run'? Trends in Cell Biology. 4: 1-4. PMID 14731821 DOI: 10.1016/0962-8924(94)90025-6  0.374
1994 Clementi E, Martino G, Grimaldi LM, Brambilla E, Meldolesi J. Intracellular Ca2+ stores of T lymphocytes: changes induced by in vitro and in vivo activation. European Journal of Immunology. 24: 1365-71. PMID 8206096 DOI: 10.1002/Eji.1830240619  0.439
1994 Racchetti G, Papazafiri P, Volpe P, Meldolesi J. Calstorin, a new Ca2+ binding protein of the microsome lumen which is abundant in the rat brain. Biochemical and Biophysical Research Communications. 203: 828-33. PMID 8093063 DOI: 10.1006/Bbrc.1994.2257  0.377
1994 Villa A, Meldolesi J. The control of Ca2+ homeostasis: Role of intracellular rapidly exchanging Ca2+ stores Cell Biology International. 18: 301-307. PMID 8049675 DOI: 10.1006/Cbir.1994.1078  0.408
1994 Villa A, Podini P, Panzeri MC, Racchetti G, Meldolesi J. Cytosolic Ca2+ binding proteins during rat brain ageing: loss of calbindin and calretinin in the hippocampus, with no change in the cerebellum. The European Journal of Neuroscience. 6: 1491-9. PMID 8000572 DOI: 10.1111/J.1460-9568.1994.Tb01010.X  0.377
1994 Valtorta F, Meldolesi J. The presynaptic compartment: signals and targets. Seminars in Cell Biology. 5: 211-9. PMID 7994005 DOI: 10.1006/Scel.1994.1027  0.361
1994 Papazafiri P, Bossi M, Meldolesi J. Expression of muscle calsequestrin in epithelial HeLa cells: distribution and functional role. Biochimica Et Biophysica Acta. 1223: 333-40. PMID 7918667 DOI: 10.1016/0167-4889(94)90092-2  0.476
1994 D'Andrea P, Codazzi F, Zacchetti D, Meldolesi J, Grohovaz F. Oscillations of cytosolic calcium in rat chromaffin cells: dual modulation in frequency and amplitude. Biochemical and Biophysical Research Communications. 205: 1264-9. PMID 7528499 DOI: 10.1006/Bbrc.1994.2801  0.361
1993 D'Andrea P, Zacchetti D, Meldolesi J, Grohovaz F. Mechanism of [Ca2+], oscillations in rat chromaffin cells: Complex Ca2+-dependent regulation of a ryanodine-insensitive oscillator Journal of Biological Chemistry. 268: 15213-15220. PMID 8392069  0.305
1993 Villa A, Podini P, Panzeri MC, Söling HD, Volpe P, Meldolesi J. The endoplasmic-sarcoplasmic reticulum of smooth muscle: immunocytochemistry of vas deferens fibers reveals specialized subcompartments differently equipped for the control of Ca2+ homeostasis. The Journal of Cell Biology. 121: 1041-51. PMID 8388876 DOI: 10.1083/Jcb.121.5.1041  0.415
1993 Rusakov DA, Podini P, Villa A, Meldolesi J. Tridimensional organization of Purkinje neuron cisternal stacks, a specialized endoplasmic reticulum subcompartment rich in inositol 1,4,5-trisphosphate receptors. Journal of Neurocytology. 22: 273-82. PMID 8386750 DOI: 10.1007/Bf01187126  0.38
1993 Meldolesi J, Villa A. Endoplasmic reticulum and the control of Ca2+ homeostasis Sub-Cellular Biochemistry. 21: 189-207. PMID 8256267 DOI: 10.1007/978-1-4615-2912-5_9  0.414
1993 Villa A, Podini P, Nori A, Panzeri MC, Martini A, Meldolesi J, Volpe P. The endoplasmic reticulum-sarcoplasmic reticulum connection: II. Postnatal differentiation of the sarcoplasmic reticulum in skeletal muscle fibers Experimental Cell Research. 209: 140-148. PMID 8223998 DOI: 10.1006/Excr.1993.1294  0.341
1993 Ciardo A, Meldolesi J. Effects of the HIV-1 envelope glycoprotein gp120 in cerebellar cultures. [Ca2+(i)] increases in a glial cell subpopulation European Journal of Neuroscience. 5: 1711-1718. PMID 8124521 DOI: 10.1111/J.1460-9568.1993.Tb00238.X  0.417
1992 Clementi E, Racchetti G, Zacchetti D, Panzeri MC, Meldolesi J. Differential Expression of Markers and Activities in a Group of PC12 Nerve Cell Clones. The European Journal of Neuroscience. 4: 944-953. PMID 12106430 DOI: 10.1111/J.1460-9568.1992.Tb00121.X  0.426
1992 Volpe P, Villa A, Podini P, Martini A, Nori A, Panzeri MC, Meldolesi J. The endoplasmic reticulum-sarcoplasmic reticulum connection: Distribution of endoplasmic reticulum markers in the sarcoplasmic reticulum of skeletal muscle fibers Proceedings of the National Academy of Sciences of the United States of America. 89: 6142-6146. PMID 1631100 DOI: 10.1073/Pnas.89.13.6142  0.399
1992 Meldolesi J, Villa A, Podini P, Clementi E, Zacchetti D, D'Andrea P, Lorenzon P, Grohovaz F. Intracellular Ca2+ stores in neurons. Identification and functional aspects Journal of Physiology - Paris. 86: 23-30. PMID 1343593 DOI: 10.1016/S0928-4257(05)80004-X  0.44
1992 Grohovaz F, Zacchetti D, D' Andrea P, Lorenzon P, Meldolesi J. [Ca2+]i effects of bradykinin B2 receptor activation in PC12 cells Agents and Actions Supplements. 38: Pt 2/-. PMID 1334345  0.337
1992 Villa A, Sharp AH, Racchetti G, Podini P, Bole DG, Dunn WA, Pozzan T, Snyder SH, Meldolesi J. The endoplasmic reticulum of Purkinje neuron body and dendrites: molecular identity and specializations for Ca2+ transport. Neuroscience. 49: 467-77. PMID 1331857 DOI: 10.1016/0306-4522(92)90111-E  0.506
1992 Clementi E, Scheer H, Zacchetti D, Racchetti G, Meldolesi J. PC12 Cell clones: experimental tools for studying transmembrane signalling and Ca2+ stores Pharmacological Research. 25: 95-96. PMID 1324494 DOI: 10.1016/1043-6618(92)90556-Q  0.407
1992 Zacchetti D, Lorenzon P, Scheer H, Clementi E, Meldolesi J, Fumagalli G, Grohovaz F. Receptor activation and CA2+ homeostasis studied by videoimaging Pharmacological Research. 25: 93-94. PMID 1324493 DOI: 10.1016/1043-6618(92)90555-P  0.376
1992 Clementi E, Scheer H, Zacchetti D, Fasolato C, Pozzan T, Meldolesi J. Receptor-activated Ca2+ influx. Two independently regulated mechanisms of influx stimulation coexist in neurosecretory PC12 cells. The Journal of Biological Chemistry. 267: 2164-72. PMID 1310310  0.324
1992 Clementi E, Scheer H, Raichman M, Meldolesi J. ATP-induced Ca2+ influx is regulated via å pertussis toxinsensitive mechanism in a PC12 cell clone Biochemical and Biophysical Research Communications. 188: 1184-1190. PMID 1280132 DOI: 10.1016/0006-291X(92)91356-U  0.454
1992 Pandiella A, Meldolesi J. Phosphoinositide hydrolysis and ensuing calcium and potassium fluxes: Role in the action of egf and other growth factors Cellular Physiology and Biochemistry. 2: 196-212. DOI: 10.1159/000154641  0.459
1992 Raichman M, Fischer J, Clementi E, Meldolesi J. IP3 receptor function in EGF-induced cell growth Pharmacological Research. 26: 149. DOI: 10.1016/1043-6618(92)91008-5  0.31
1992 Meldolesi J. Inositol phosphates and intracellular [Ca2+]i modulation Pharmacological Research. 26: 115. DOI: 10.1016/1043-6618(92)90940-D  0.381
1992 Grohovaz F, Andrea PD, Zacchetti D, Lorenzon P, Torri Tarelli F, Meldolesi J. Functional properties of rapidly exchanging Ca2+ stores in excitable cells Pharmacological Research. 26: 103. DOI: 10.1016/1043-6618(92)90916-Y  0.389
1991 Malgaroli A, Meldolesi J. [Ca2+]i oscillations from internal stores sustain exocytic secretion from the chromaffin cells of the rat. Febs Letters. 283: 169-72. PMID 2044755 DOI: 10.1016/0014-5793(91)80580-V  0.427
1991 Fasolato C, Zottini M, Clementi E, Zacchetti D, Meldolesi J, Pozzan T. Intracellular Ca2+ pools in PC12 cells. Three intracellular pools are distinguished by their turnover and mechanisms of Ca2+ accumulation, storage, and release. The Journal of Biological Chemistry. 266: 20159-67. PMID 1939077  0.32
1991 Volpe P, Villa A, Damiani E, Sharp AH, Podini P, Snyder SH, Meldolesi J. Heterogeneity of microsomal Ca2+ stores in chicken purkinje neurons Embo Journal. 10: 3183-3189. PMID 1915290  0.44
1991 Magistretti J, Dettori C, Meldolesi J. Glucose transport stimulation by bradykinin in Swiss 3T3 fibroblasts: a pertussis toxin-sensitive mechanism operates without involvement of arachidonic acid and cyclic AMP. Experimental Cell Research. 192: 67-74. PMID 1845801 DOI: 10.1016/0014-4827(91)90158-Q  0.362
1991 Michelangeli F, Di Virgilio F, Villa A, Podini P, Meldolesi J, Pozzan T. Identification, kinetic properties and intracellular localization of the (Ca(2+)-Mg2+)-ATPase from the intracellular stores of chicken cerebellum. The Biochemical Journal. 275: 555-61. PMID 1828146 DOI: 10.1042/Bj2750555  0.412
1991 Villa A, Podini P, Clegg DO, Pozzan T, Meldolesi J. Intracellular Ca2+ stores in chicken Purkinje neurons: differential distribution of the low affinity-high capacity Ca2+ binding protein, calsequestrin, of Ca2+ ATPase and of the ER lumenal protein, Bip. The Journal of Cell Biology. 113: 779-91. PMID 1827445 DOI: 10.1083/Jcb.113.4.779  0.443
1991 Magni M, Meldolesi J, Pandiella A. Ionic events induced by epidermal growth factor: Evidence that hyperpolarization and stimulated cation influx play a role in the stimulation of cell growth Journal of Biological Chemistry. 266: 6329-6335. PMID 1706715  0.334
1991 Ciardo A, Meldolesi J. Regulation of intracellular calcium in cerebellar granule neurons: Effects of depolarization and of glutamatergic and cholinergic stimulation Journal of Neurochemistry. 56: 184-191. PMID 1670951 DOI: 10.1111/J.1471-4159.1991.Tb02579.X  0.384
1991 Meldolesi J, Clementi E, Fasolato C, Zacchetti D, Pozzan T. Ca2+ influx following receptor activation. Trends in Pharmacological Sciences. 12: 289-92. PMID 1658997 DOI: 10.1016/0165-6147(91)90577-F  0.379
1991 Zacchetti D, Clementi E, Fasolato C, Lorenzon P, Zottini M, Grohovaz F, Fumagalli G, Pozzan T, Meldolesi J. Intracellular Ca2+ pools in PC12 cells. A unique, rapidly exchanging pool is sensitive to both inositol 1,4,5-trisphosphate and caffeine-ryanodine. The Journal of Biological Chemistry. 266: 20152-8. PMID 1657914  0.326
1991 Grohovaz F, Zacchetti D, Clementi E, Lorenzon P, Meldolesi J, Fumagalli G. [Ca2+]i imaging in PC12 cells: Multiple response patterns to receptor activation reveal new aspects of transmembrane signaling Journal of Cell Biology. 113: 1341-1350. PMID 1646204 DOI: 10.1083/Jcb.113.6.1341  0.431
1990 Meldolesi J, Madeddu L, Pozzan T. Intracellular Ca2+ storage organelles in non-muscle cells: heterogeneity and functional assignment. Biochimica Et Biophysica Acta. 1055: 130-40. PMID 2242382 DOI: 10.1016/0167-4889(90)90113-R  0.305
1990 Satoh T, Ross CA, Villa A, Supattapone S, Pozzan T, Snyder SH, Meldolesi J. The inositol 1,4,5,-trisphosphate receptor in cerebellar Purkinje cells: quantitative immunogold labeling reveals concentration in an ER subcompartment. The Journal of Cell Biology. 111: 615-24. PMID 2166053 DOI: 10.1083/Jcb.111.2.615  0.555
1990 Ciardo A, Meldolesi J. Multiple actions of SC 38249: the blocker of both voltage-operated and second messenger-operated Ca2+ channels also inhibits Ca2+ extrusion European Journal of Pharmacology: Molecular Pharmacology. 188: 417-421. PMID 2164944 DOI: 10.1016/0922-4106(90)90204-B  0.374
1990 Milani D, Malgaroli A, Guidolin D, Fasolato C, Skaper SD, Meldolesi J, Pozzan T. Ca2+ channels and intracellular Ca2+ stores in neuronal and neuroendocrine cells. Cell Calcium. 11: 191-9. PMID 2162259 DOI: 10.1016/0143-4160(90)90070-B  0.423
1990 Torri Tarelli F, Valtorta F, Villa A, Meldolesi J. Functional morphology of the nerve terminal at the frog neuromuscular junction: recent insights using immunocytochemistry. Progress in Brain Research. 84: 83-92. PMID 2125131 DOI: 10.1016/S0079-6123(08)60891-2  0.319
1990 Malgaroli A, Fesce R, Meldolesi J. Spontaneous [Ca2+]i fluctuations in rat chromaffin cells do not require inositol 1,4,5-trisphosphate elevations but are generated by a caffeine- and ryanodine-sensitive intracellular Ca2+ store. The Journal of Biological Chemistry. 265: 3005-8. PMID 2105938  0.326
1990 Volpe P, Pozzan T, Meldolesi J. Rapidly exchanging Ca2+ stores of non-muscle cells. Seminars in Cell Biology. 1: 297-304. PMID 2103514  0.334
1990 McMahon HT, Rosenthal L, Meldolesi J, Nicholls DG. Alpha-latrotoxin releases both vesicular and cytoplasmic glutamate from isolated nerve terminals. Journal of Neurochemistry. 55: 2039-47. PMID 1977887 DOI: 10.1111/J.1471-4159.1990.Tb05793.X  0.326
1990 Meldolesi J, Villa A, Satoh T, Podini P, Balsari S, Malgaroli A, Pozzan T. Ca2+ release from intracellular stores to the cytosol: Identification of the mechanisms and of the organelles involved Pharmacological Research. 22: 322. DOI: 10.1016/S1043-6618(09)80347-2  0.417
1990 ROSENTHAL L, ZACCHETTI D, SALUGERI E, MELDOLESI J. ?-Latrotoxin-induced CA2-independent dopamine release in PC12 cells Cell Biology International Reports. 14: 145. DOI: 10.1016/0309-1651(90)90680-W  0.396
1990 VILLA A, SATOH T, PODINI P, BALSARI S, ROSS C, CLEGG D, SNYDER S, POZZAN T, MELDOLESI J. Immuno-mapping of the specific receptor and other antigens reveals that the IP3-sensitive Ca2+ storage organelle is an ER subcompartment Cell Biology International Reports. 14: 109. DOI: 10.1016/0309-1651(90)90536-8  0.469
1990 MAGNI M, PANDIELLA A, MELDOLESI J. Ionic events induced by EGF: Intracellular Ca2+ release, Ca2+ influx and membrane hyperpolarization Cell Biology International Reports. 14: 67. DOI: 10.1016/0309-1651(90)90374-8  0.45
1990 MELDOLESI J. Mechanisms of intracellular Ca2+ regulation Cell Biology International Reports. 14: 1. DOI: 10.1016/0309-1651(90)90119-J  0.389
1989 Pandiella A, Magni M, Meldolesi J. Plasma membrane hyperpolarization and [Ca2+]i increase induced by fibroblast growth factor in NIH-3T3 fibroblasts: Resemblance to early signals generated by platelet-derived growth factor Biochemical and Biophysical Research Communications. 163: 1325-1331. PMID 2783138 DOI: 10.1016/0006-291X(89)91123-6  0.44
1989 Janigro D, Maccaferri G, Meldolesi J. Are undifferentiated PC12 rat pheochromocytoma cells electrically excitable? Biochemical and Biophysical Research Communications. 163: 810-4. PMID 2783122 DOI: 10.1016/0006-291X(89)92294-8  0.39
1989 Vallar L, Meldolesi J. Mechanisms of signal transduction at the dopamine D2 receptor Trends in Pharmacological Sciences. 10: 74-77. PMID 2655242 DOI: 10.1016/0165-6147(89)90082-5  0.406
1989 Pandiella A, Lehvaslaiho H, Magni M, Alitalo K, Meldolesi J. Activation of an EGFR/neu chimeric receptor: early intracellular signals and cell proliferation responses Oncogene. 4: 1299-1305. PMID 2573029  0.318
1989 Malgaroli A, DeCamilli P, Meldolesi J. Distribution of alpha latrotoxin receptor in the rat brain by quantitative autoradiography: comparison with the nerve terminal protein, synapsin I. Neuroscience. 32: 393-404. PMID 2555739 DOI: 10.1016/0306-4522(89)90088-2  0.332
1989 Janigro D, Maccaferri G, Meldolesi J. Calcium channels in undifferentiated PC12 rat pheochromocytoma cells. Febs Letters. 255: 398-400. PMID 2551740 DOI: 10.1016/0014-5793(89)81131-7  0.315
1989 Krause KH, Pittet D, Volpe P, Pozzan T, Meldolesi J, Lew DP. Calciosome, a sarcoplasmic reticulum-like organelle involved in intracellular Ca2+-handling by non-muscle cells: studies in human neutrophils and HL-60 cells. Cell Calcium. 10: 351-61. PMID 2548728 DOI: 10.1016/0143-4160(89)90061-4  0.461
1989 Ross CA, Meldolesi J, Milner TA, Satoh T, Supattapone S, Snyder SH. Inositol 1,4,5-trisphosphate receptor localized to endoplasmic reticulum in cerebellar Purkinje neurons. Nature. 339: 468-70. PMID 2542801 DOI: 10.1038/339468A0  0.569
1989 Dettori C, Meldolesi J. Regulation of glucose transport by insulin, bombesin, and bradykinin in Swiss 3T3 fibroblasts: Involvement of protein kinase C-dependent and -independent mechanisms Experimental Cell Research. 182: 267-278. PMID 2541005 DOI: 10.1016/0014-4827(89)90297-8  0.307
1988 Pandiella A, Vicentini LM, Meldolesi J. Protein kinase C-mediated feed back inhibition of the Ca2+ response at the EGF receptor. Biochemical and Biophysical Research Communications. 149: 145-51. PMID 3500722 DOI: 10.1016/0006-291X(87)91616-0  0.419
1988 Volpe P, Krause KH, Hashimoto S, Zorzato F, Pozzan T, Meldolesi J, Lew DP. "Calciosome," a cytoplasmic organelle: the inositol 1,4,5-trisphosphate-sensitive Ca2+ store of nonmuscle cells? Proceedings of the National Academy of Sciences of the United States of America. 85: 1091-5. PMID 3257572 DOI: 10.1073/Pnas.85.4.1091  0.462
1988 Fasolato C, Pandiella A, Meldolesi J, Pozzan T. Generation of inositol phosphates, cytosolic Ca2+, and ionic fluxes in PC12 cells treated with bradykinin. The Journal of Biological Chemistry. 263: 17350-9. PMID 3141420  0.339
1988 Malgaroli A, Hashimoto S, Grohovaz F, Fumagalli G, Pozzan T, Meldolesi J. Intracellular source(s) of [Ca2+]i transients in nonmuscle cells. Annals of the New York Academy of Sciences. 551: 159-66; discussion 1. PMID 3072901 DOI: 10.1111/J.1749-6632.1988.Tb22334.X  0.397
1988 Hashimoto S, Bruno B, Lew DP, Pozzan T, Volpe P, Meldolesi J. Immunocytochemistry of calciosomes in liver and pancreas. The Journal of Cell Biology. 107: 2523-31. PMID 2974458 DOI: 10.1083/Jcb.107.6.2523  0.439
1988 Meldolesi J, Gatti G, Ambrosini A, Pozzan T, Westhead EW. Second-messenger control of catecholamine release from PC12 cells. Role of muscarinic receptors and nerve-growth-factor-induced cell differentiation. The Biochemical Journal. 255: 761-8. PMID 2850796 DOI: 10.1042/Bj2550761  0.431
1988 Gatti G, Madeddu L, Pandiella A, Pozzan T, Meldolesi J. Second-messenger generation in PC12 cells. Interactions between cyclic AMP and Ca2+ signals. The Biochemical Journal. 255: 753-60. PMID 2850795 DOI: 10.1042/Bj2550753  0.414
1988 Pandiella A, Beguinot L, Velu TJ, Meldolesi J. Transmembrane signalling at epidermal growth factor receptors overexpressed in NIH 3T3 cells. Phosphoinositide hydrolysis, cytosolic Ca2+ increase and alkalinization correlate with epidermal-growth-factor-induced cell proliferation. The Biochemical Journal. 254: 223-8. PMID 2845945 DOI: 10.1042/Bj2540223  0.426
1988 Pozzan T, Volpe P, Zorzato F, Bravin M, Lew DP, Krause KH, Hashimoto S, Bruno B, Meldolesi J. Immunocytological identification of the microsomal calcium store of nonmuscle cells. Journal of Cardiovascular Pharmacology. 12: S80-4. PMID 2469883 DOI: 10.1097/00005344-198800125-00014  0.471
1988 Meldolesi J, Volpe P, Pozzan T. The intracellular distribution of calcium. Trends in Neurosciences. 11: 449-52. PMID 2469163 DOI: 10.1016/0166-2236(88)90197-X  0.408
1988 Meldolesi J, Ceccarelli B. Chapter 5 Exocytosis and Membrane Recycling Current Topics in Membranes and Transport. 32: 139-168. DOI: 10.1016/S0070-2161(08)60133-1  0.422
1988 Malgaroli A, Meldolesi J. Control of resting [Ca2+]i in single chromaffin cells: Evidence for an oscillatory behaviour Pharmacological Research Communications. 20: 221. DOI: 10.1016/S0031-6989(88)80351-5  0.392
1987 Malgaroli A, Milani D, Meldolesi J, Pozzan T. Fura-2 measurement of cytosolic free Ca2+ in monolayers and suspensions of various types of animal cells. The Journal of Cell Biology. 105: 2145-55. PMID 3680375 DOI: 10.1083/Jcb.105.5.2145  0.413
1987 Hashimoto S, Fumagalli G, Zanini A, Meldolesi J. Sorting of three secretory proteins to distinct secretory granules in acidophilic cells of cow anterior pituitary. The Journal of Cell Biology. 105: 1579-86. PMID 3667692 DOI: 10.1083/Jcb.105.4.1579  0.383
1987 Saito I, Hashimoto S, Saluja A, Steer ML, Meldolesi J. Intracellular transport of pancreatic zymogens during caerulein supramaximal stimulation American Journal of Physiology - Gastrointestinal and Liver Physiology. 253. PMID 3661711 DOI: 10.1152/Ajpgi.1987.253.4.G517  0.318
1987 Pandiella A, Malgaroli A, Meldolesi J, Vicentini LM. EGF raises cytosolic Ca2+ in A431 and Swiss 3T3 cells by a dual mechanism. Redistribution from intracellular stores and stimulated influx. Experimental Cell Research. 170: 175-85. PMID 3494624 DOI: 10.1016/0014-4827(87)90127-3  0.429
1987 Haimann C, Meldolesi J, Ceccarelli B. The phorbol ester, 12-O-tetradecanoyl-phorbol-13-acetate, enhances the evoked quanta release of acetylcholine at the frog neuromuscular junction. Pflugers Archiv : European Journal of Physiology. 408: 27-31. PMID 3493479 DOI: 10.1007/Bf00581836  0.364
1987 Meldolesi J, Pozzan T. Pathways of Ca2+ influx at the plasma membrane: voltage-, receptor-, and second messenger-operated channels. Experimental Cell Research. 171: 271-83. PMID 2442017 DOI: 10.1016/0014-4827(87)90161-3  0.393
1987 Wanke E, Ferroni A, Malgaroli A, Ambrosini A, Pozzan T, Meldolesi J. Activation of a muscarinic receptor selectively inhibits a rapidly inactivated Ca2+ current in rat sympathetic neurons. Proceedings of the National Academy of Sciences of the United States of America. 84: 4313-7. PMID 2438697 DOI: 10.1073/Pnas.84.12.4313  0.395
1987 Prestipino G, Scheer H, Meldolesi J. Electrical properties of a purified complex of α-latrotoxin and its receptor incorporated into planar lipid bilayers Bioelectrochemistry and Bioenergetics. 17: 361-368. DOI: 10.1016/0302-4598(87)80046-6  0.369
1987 Vallar L, Malgaroli A, Vicentini L, Spada A, Meldolesi J. Dopamine inhibits TRH-INDUCED Ca2+ mobilization from intracellular stores in rat lactotroph cells Pharmacological Research Communications. 19: 959-960. DOI: 10.1016/0031-6989(87)90051-8  0.377
1987 Malgaroli A, Vallar L, Spada A, Ciardo A, Meldolesi J. Internal Ca2+ fluctuations in rat lactotroph cells:Inhibitory effect of dopamine Pharmacological Research Communications. 19: 957-958. DOI: 10.1016/0031-6989(87)90050-6  0.363
1986 Pozzan T, Di Virgilio F, Vicentini LM, Meldolesi J. Activation of muscarinic receptors in PC12 cells. Stimulation of Ca2+ influx and redistribution. The Biochemical Journal. 234: 547-53. PMID 3718485 DOI: 10.1042/Bj2340547  0.431
1986 Pandiella-Alonso A, Malgaroli A, Vicentini LM, Meldolesi J. Early rise of cytosolic Ca2+ induced by NGF in PC12 and chromaffin cells. Febs Letters. 208: 48-51. PMID 3490405 DOI: 10.1016/0014-5793(86)81529-0  0.404
1986 Vicentini LM, Ambrosini A, Di Virgilio F, Meldolesi J, Pozzan T. Activation of muscarinic receptors in PC12 cells. Correlation between cytosolic Ca2+ rise and phosphoinositide hydrolysis. The Biochemical Journal. 234: 555-62. PMID 3013159 DOI: 10.1042/Bj2340555  0.45
1986 Sturani E, Vicentini LM, Zippel R, Toschi L, Pandiella-Alonso A, Comoglio PM, Meldolesi J. PDGF-induced receptor phosphorylation and phosphoinositide hydrolysis are unaffected by protein kinase C activation in mouse Swiss 3T3 and human skin fibroblasts. Biochemical and Biophysical Research Communications. 137: 343-50. PMID 2424446 DOI: 10.1016/0006-291X(86)91216-7  0.342
1986 Wanke E, Ferroni A, Gattanini P, Meldolesi J. alpha Latrotoxin of the black widow spider venom opens a small, non-closing cation channel. Biochemical and Biophysical Research Communications. 134: 320-5. PMID 2418826 DOI: 10.1016/0006-291X(86)90565-6  0.387
1986 Meldolesi J, Scheer H, Madeddu L, Wanke E. Mechanism of action of α-latrotoxin: the presynaptic stimulatory toxin of the black widow spider venom Trends in Pharmacological Sciences. 7: 151-155. DOI: 10.1016/0165-6147(86)90293-2  0.413
1986 Scheer H, Prestipino G, Meldolesi J. Reconstitution of the purified alpha-latrotoxin receptor in liposomes and planar lipid membranes. Clues to the mechanism of toxin action. The Embo Journal. 5: 2643-2648. DOI: 10.1002/J.1460-2075.1986.Tb04546.X  0.352
1985 Vicentini LM, Ambrosini A, Di Virgilio F, Pozzan T, Meldolesi J. Muscarinic receptor-induced phosphoinositide hydrolysis at resting cytosolic Ca2+ concentration in PC12 cells. The Journal of Cell Biology. 100: 1330-3. PMID 2984215 DOI: 10.1083/Jcb.100.4.1330  0.46
1985 Vicentini LM, Di Virgilio F, Ambrosini A, Pozzan T, Meldolesi J. Tumor promoter phorbol 12-myristate, 13-acetate inhibits phosphoinositide hydrolysis and cytosolic Ca2+ rise induced by the activation of muscarinic receptors in PC12 cells. Biochemical and Biophysical Research Communications. 127: 310-7. PMID 2983712 DOI: 10.1016/S0006-291X(85)80160-1  0.385
1985 Saito I, Dozio N, Meldolesi J. The effect of alpha-latrotoxin on the neurosecretory PC12 cells differentiated by treatment with nerve growth factor. Neuroscience. 14: 1163-74. PMID 2860617 DOI: 10.1016/0306-4522(85)90285-4  0.366
1985 Saluja A, Saito I, Saluja M, Houlihan MJ, Powers RE, Meldolesi J, Steer M. In vivo rat pancreatic acinar cell function during supramaximal stimulation with caerulein. The American Journal of Physiology. 249: G702-10. PMID 2417493 DOI: 10.1152/Ajpgi.1985.249.6.G702  0.352
1985 Madeddu L, Saito I, Hsiao TH, Meldolesi J. Leptinotoxin-h action in synaptosomes and neurosecretory cells: stimulation of neurotransmitter release. Journal of Neurochemistry. 45: 1719-30. PMID 2414401 DOI: 10.1111/J.1471-4159.1985.Tb10527.X  0.439
1985 Madeddu L, Pozzan T, Robello M, Rolandi R, Hsiao TH, Meldolesi J. Leptinotoxin-h action in synaptosomes, neurosecretory cells, and artificial membranes: stimulation of ion fluxes. Journal of Neurochemistry. 45: 1708-18. PMID 2414400 DOI: 10.1111/J.1471-4159.1985.Tb10526.X  0.468
1985 Scheer H, Meldolesi J. Purification of the putative alpha-latrotoxin receptor from bovine synaptosomal membranes in an active binding form. The Embo Journal. 4: 323-327. DOI: 10.1002/J.1460-2075.1985.Tb03632.X  0.321
1984 Watanabe O, Baccino FM, Steer ML, Meldolesi J. Supramaximal caerulein stimulation and ultrastructure of rat pancreatic acinar cell: early morphological changes during development of experimental pancreatitis. The American Journal of Physiology. 246: G457-67. PMID 6720895 DOI: 10.1152/Ajpgi.1984.246.4.G457  0.326
1984 Meldolesi J. Membranes of pancreatic zymogen granules. Methods in Enzymology. 98: 67-75. PMID 6669071 DOI: 10.1016/0076-6879(83)98140-5  0.392
1984 Meldolesi J, Madeddu L, Torda M, Gatti G, Niutta E. The effect of alpha-latrotoxin on the neurosecretory PC12 cell line: studies on toxin binding and stimulation of transmitter release. Neuroscience. 10: 997-1009. PMID 6646442 DOI: 10.1016/0306-4522(83)90238-5  0.417
1984 Watanabe O, Torda M, Meldolesi J. The effect of alpha-latrotoxin on the neurosecretory PC12 cell line: electron microscopy and cytotoxicity studies. Neuroscience. 10: 1011-24. PMID 6646424 DOI: 10.1016/0306-4522(83)90239-7  0.433
1984 Pozzan T, Gatti G, Dozio N, Vicentini LM, Meldolesi J. Ca2+-dependent and -independent release of neurotransmitters from PC12 cells: a role for protein kinase C activation? The Journal of Cell Biology. 99: 628-38. PMID 6204995 DOI: 10.1083/Jcb.99.2.628  0.449
1984 Madeddu L, Meldolesi J, Pozzan T, Cardona Sanclemente LE, Bon C. Alpha-latrotoxin and glycerotoxin differ in target specificity and in the mechanism of their neurotransmitter releasing action. Neuroscience. 12: 939-49. PMID 6147793 DOI: 10.1016/0306-4522(84)90181-7  0.471
1984 Vicentini LM, Meldolesi J. alpha Latrotoxin of black widow spider venom binds to a specific receptor coupled to phosphoinositide breakdown in PC12 cells. Biochemical and Biophysical Research Communications. 121: 538-44. PMID 6145415 DOI: 10.1016/0006-291X(84)90215-8  0.361
1984 Meldolesi J, Huttner WB, Tsien RY, Pozzan T. Free cytoplasmic Ca2+ and neurotransmitter release: studies on PC12 cells and synaptosomes exposed to alpha-latrotoxin. Proceedings of the National Academy of Sciences of the United States of America. 81: 620-4. PMID 6141561 DOI: 10.1073/Pnas.81.2.620  0.426
1984 POZZAN T, VIRGILIO FD, GATTI G, DOZIO N, MELDOLESI J. Relationship between neurotransmitter release and cytosolic free calcium in PC12 cells Biochemical Society Transactions. 12: 1077-1077. DOI: 10.1042/Bst0121077  0.339
1983 Watanabe O, Meldolesi J. The effects of alpha-latrotoxin of black widow spider venom on synaptosome ultrastructure. A morphometric analysis correlating its effects on transmitter release. Journal of Neurocytology. 12: 517-31. PMID 6875622 DOI: 10.1007/Bf01159388  0.4
1982 Meldolesi J. Studies on alpha-latrotoxin receptors in rat brain synaptosomes: correlation between toxin binding and stimulation of transmitter release. Journal of Neurochemistry. 38: 1559-69. PMID 7077326 DOI: 10.1111/J.1471-4159.1982.Tb06633.X  0.33
1982 Koike H, Steer ML, Meldolesi J. Pancreatic effects of ethionine: blockade of exocytosis and appearance of crinophagy and autophagy precede cellular necrosis The American Journal of Physiology. 242. PMID 7065251 DOI: 10.1152/Ajpgi.1982.242.4.G297  0.373
1982 Nicholls DG, Rugolo M, Scott IG, Meldolesi J. alpha-latrotoxin of black widow spider venom depolarizes the plasma membrane, induces massive calcium influx, and stimulates transmitter release in guinea pig brain synaptosomes. Proceedings of the National Academy of Sciences of the United States of America. 79: 7924-8. PMID 6961460 DOI: 10.1073/Pnas.79.24.7924  0.437
1981 Koike H, Meldolesi J. Post-stimulation retrieval of luminal surface membrane in parotid acinar cells is calcium-dependent Experimental Cell Research. 134: 377-388. PMID 7274338 DOI: 10.1016/0014-4827(81)90437-7  0.489
1981 Meldolesi J, Borgese N. Membrane synthesis and turnover in secretory cell systems. Methods in Cell Biology. 23: 445-60. PMID 7035809 DOI: 10.1016/S0091-679X(08)61513-7  0.398
1980 Borgese N, Pietrini G, Meldolesi J. Localization and biosynthesis of NADH-cytochrome b5 reductase, an iontegral membrane protein, in rat liver cells. III. Evidence for the independent insertion and turnover the enzyme in various subcellular compartments. The Journal of Cell Biology. 86: 38-45. PMID 7419581 DOI: 10.1083/Jcb.86.1.38  0.317
1980 Zanini A, Giannattasio G, Nussdorfer G, Margolis RK, Margolis RU, Meldolesi J. Molecular organization of prolactin granules. II. Characterization of glycosaminoglycans and glycoproteins of the bovine prolactin matrix Journal of Cell Biology. 86: 260-272. PMID 7419576 DOI: 10.1083/Jcb.86.1.260  0.354
1980 Meldolesi J, Corte G, Pietrini G, Borgese N. Localization and biosynthesis of NADH-cytochrome b5 reductase, an integral membrane protein, in rat liver cells. II. Evidence that a single enzyme accounts for the activity in its various subcellular locations. The Journal of Cell Biology. 85: 516-26. PMID 7391132 DOI: 10.1083/Jcb.85.3.516  0.323
1980 Borgese N, Meldolesi J. Localization and biosynthesis of NADH-cytochrome b5 reductase, an integral membrane protein, in rat liver cells. I. Distribution of the enzyme activity in microsomes, mitochondria, and golgi complex. The Journal of Cell Biology. 85: 501-15. PMID 7391131 DOI: 10.1083/Jcb.85.3.501  0.32
1980 Tanaka Y, De Camilli P, Meldolesi J. Membrane interactions between secretion granules and plasmalemma in three exocrine glands Journal of Cell Biology. 84: 438-453. PMID 7380885 DOI: 10.1083/Jcb.84.2.438  0.583
1980 Bonatti S, Cerasuolo A, Cancedda R, Borgese N, Meldolesi J. Studies on the intracellular distribution of Sindbis messenger RNA in infected chick-embryo fibroblasts. 1. Presence of extrapolyribosomal 26-S RNA in the membrane fraction. European Journal of Biochemistry / Febs. 103: 53-64. PMID 7358048 DOI: 10.1111/J.1432-1033.1980.Tb04288.X  0.336
1980 Giannattasio G, Zanini A, Rosa P, Meldolesi J, Margolis RK, margolis RU. Molecular organization of prolactin granules. III. Intracellular transport of sulfated glycosaminoglycans and glycoproteins of the bovine prolactin granule matrix Journal of Cell Biology. 86: 273-279. PMID 6774983 DOI: 10.1083/Jcb.86.1.273  0.351
1979 Zanini A, Giannattasio G, de Camilli P, Panerai AE, Müller EE, Meldolesi J. Studies on rat pituitary homografts. I. In vitro biosynthesis and release of growth hormone and prolactin Endocrinology. 104: 226-236. PMID 446350 DOI: 10.1210/Endo-104-1-226  0.516
1978 Meldolesi J, Castiglioni G, Parma R, Nassivera N, De Camilli P. Ca ++-dependent disassembly and reassembly of occluding junctions in guinea pig pancreatic acinar cells. Effect of drugs Journal of Cell Biology. 79: 156-172. PMID 701369 DOI: 10.1083/Jcb.79.1.156  0.579
1978 Ceccarelli B, Hurlbut WP, De Camilli P, Meldolesi J. The effect of extracellular calcium on the topological organization of the plasmalemma in two secretory systems Annals of the New York Academy of Sciences. 307: 653-655. PMID 280279 DOI: 10.1111/j.1749-6632.1978.tb41990.x  0.387
1976 Clemente F, Meldolesi J. Calcium and pancreatic secretion-dynamics of subcellur calcium pools in resting and stimulated acinar cells. British Journal of Pharmacology. 55: 369-79. PMID 1203623 DOI: 10.1111/J.1476-5381.1975.Tb06940.X  0.46
1976 De Camilli P, Peluchetti D, Meldolesi J. Dynamic changes of the luminal plasmalemma in stimulated parotid acinar cells. A freeze fracture study Journal of Cell Biology. 70: 59-74. PMID 932102 DOI: 10.1083/Jcb.70.1.59  0.569
1976 Galli P, Brenna A, De Camilli P, Meldolesi J. Extracellular calcium and the organization of tight junctions in pancreatic acinar cells Experimental Cell Research. 99: 178-183. PMID 816663 DOI: 10.1016/0014-4827(76)90694-7  0.524
1976 Borgese N, Meldolesi J. Immunological similarity of the NADH-cytochrome c electron transport system in microsomes, Golgi complex and mitochondrial outer membrane of rat liver cells. Febs Letters. 63: 231-4. PMID 177314 DOI: 10.1016/0014-5793(76)80101-9  0.316
1975 Ceccarelli B, Clemente F, Meldolesi J. Secretion of calcium in pancreatic juice. The Journal of Physiology. 245: 617-38. PMID 1142221 DOI: 10.1113/Jphysiol.1975.Sp010865  0.403
1975 Clemente F, Meldolesi J. Calcium and pancreatic secretion. I. Subcellular distribution of calcium and magnesium in the exocrine pancreas of the guinea pig. The Journal of Cell Biology. 65: 88-102. PMID 165206 DOI: 10.1083/Jcb.65.1.88  0.369
1975 Giannattasio G, Zanini A, Meldolesi J. Molecular organization of rat prolactin granules. I. In vitro stability of intact and "membraneless" granules. The Journal of Cell Biology. 64: 246-51. PMID 45846 DOI: 10.1083/Jcb.64.1.246  0.381
1974 De Camilli P, Peluchetti D, Meldolesi J. Structural difference between luminal and lateral plasmalemma in pancreatic acinar cells Nature. 248: 245-247. PMID 4819419 DOI: 10.1038/248245B0  0.583
1974 Meldolesi J. Dynamics of cytoplasmic membranes in guinea pig pancreatic acinar cells. I. Synthesis and turnover of membrane proteins. The Journal of Cell Biology. 61: 1-13. PMID 4819305 DOI: 10.1083/Jcb.61.1.1  0.414
1974 Camilli PD, Meldolesi J. Subcellular distribution of the pi effect in the pancreas of the guinea pig Life Sciences. 15: 711-721. PMID 4549938 DOI: 10.1016/0024-3205(74)90509-8  0.379
1973 Meldolesi J, Cova D. Composition of cellular membranes in the pancreas of the guinea pig. IV. Polyacrylamide gel electrophoresis and amino acid composition of membrane proteins. The Journal of Cell Biology. 55: 1-18. PMID 4653415 DOI: 10.1083/Jcb.55.1.1  0.39
1972 Meldolesi J, Cova D. Synthesis and interactions of cytoplasmic membranes in the pancreatic exocrine cells. Biochemical and Biophysical Research Communications. 44: 139-43. PMID 5116504 DOI: 10.1016/S0006-291X(71)80169-9  0.402
1971 Meldolesi J, Jamieson JD, Palade GE. Composition of cellular membranes in the pancreas of the guinea pig. II. Lipids. The Journal of Cell Biology. 49: 130-49. PMID 5555573 DOI: 10.1083/Jcb.49.1.130  0.67
1971 Meldolesi J, Cova D. In vitro stimulation of enzyme secretion and the synthesis of microsomal membranes in the pancreas of the guinea pig. The Journal of Cell Biology. 51: 396-404. PMID 4329615 DOI: 10.1083/jcb.51.2.396  0.312
1971 Meldolesi J, Jamieson JD, Palade GE. Composition of cellular membranes in the pancreas of the guinea pig. 3. Enzymatic activities. The Journal of Cell Biology. 49: 150-8. PMID 4324565 DOI: 10.1083/Jcb.49.1.150  0.681
1971 Meldolesi J, Jamieson JD, Palade GE. Composition of cellular membranes in the pancreas of the guinea pig. I. Isolation of membrane fractions. The Journal of Cell Biology. 49: 109-29. PMID 4324564 DOI: 10.1083/Jcb.49.1.109  0.694
1969 De Virgiliis G, Meldolesi J, Clementi F. Ultrastructure of growth hormone-producing cells of rat pituitary after injection of hypothalamic extract. Endocrinology. 83: 1278-84. PMID 4880985 DOI: 10.1210/Endo-83-6-1278  0.32
1968 Meldolesi J. Protective effects of alpha-tocopherol on the hepatotoxicty of carbon tetrachloride: an electron microscope study. Experimental and Molecular Pathology. 9: 141-7. PMID 5667364 DOI: 10.1016/0014-4800(68)90058-0  0.326
1967 Meldolesi J. On the significance of the hypertrophy of the smooth endoplasmic reticulum in liver cells after administration of drugs Biochemical Pharmacology. 16: 125-129. DOI: 10.1016/0006-2952(67)90193-1  0.334
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