Yaron Rotman - Publications

Affiliations: 
NIDDK, Bethesda, MD, United States 
Area:
Liver Disease, NAFLD, Genetics

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Velenosi TJ, Ben-Yakov G, Podszun MC, Hercun J, Etzion O, Yang S, Nadal C, Haynes-Williams V, Huang WA, Gonzalez-Hodar L, Brychta RJ, Takahashi S, Akkaraju V, Krausz KW, Walter M, ... ... Rotman Y, et al. Postprandial plasma lipidomics reveal specific alteration of hepatic-derived diacylglycerols in non-alcoholic fatty liver disease. Gastroenterology. PMID 35283114 DOI: 10.1053/j.gastro.2022.03.004  0.363
2021 Hercun J, Kim GE, Da BL, Rotman Y, Kleiner DE, Chang R, Glenn JS, Hoofnagle JH, Koh C, Heller T. Durable virological response and functional cure of chronic hepatitis D after long-term peginterferon therapy. Alimentary Pharmacology & Therapeutics. PMID 34048594 DOI: 10.1111/apt.16408  0.303
2020 Wang H, Mehal W, Nagy LE, Rotman Y. Immunological mechanisms and therapeutic targets of fatty liver diseases. Cellular & Molecular Immunology. PMID 33268887 DOI: 10.1038/s41423-020-00579-3  0.332
2020 Podszun MC, Alawad AS, Lingala S, Morris N, Huang WA, Yang S, Schoenfeld M, Rolt A, Ouwerkerk R, Valdez K, Umarova R, Ma Y, Fatima SZ, Lin DD, Mahajan LS, ... ... Rotman Y, et al. Vitamin E treatment in NAFLD patients demonstrates that oxidative stress drives steatosis through upregulation of de-novo lipogenesis. Redox Biology. 37: 101710. PMID 32920226 DOI: 10.1016/J.Redox.2020.101710  0.734
2020 Podszun MC, Chung JY, Ylaya K, Kleiner DE, Hewitt SM, Rotman Y. 4-HNE Immunohistochemistry and Image Analysis for Detection of Lipid Peroxidation in Human Liver Samples Using Vitamin E Treatment in NAFLD as a Proof of Concept. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 68: 635-643. PMID 32867573 DOI: 10.1369/0022155420946402  0.454
2020 Ma Y, Brown PM, Lin DD, Ma J, Feng D, Belyaeva OV, Podszun MC, Roszik J, Allen J, Umarova R, Kleiner DE, Kedishvili NY, Gavrilova O, Gao B, Rotman Y. Hsd17b13 Deficiency Does not Protect Mice From Obesogenic Diet Injury. Hepatology (Baltimore, Md.). PMID 32779242 DOI: 10.1002/Hep.31517  0.432
2020 Suresh RR, Jain S, Chen Z, Tosh DK, Ma Y, Podszun MC, Rotman Y, Salvemini D, Jacobson KA. Design and in vivo activity of A adenosine receptor agonist prodrugs. Purinergic Signalling. PMID 32720036 DOI: 10.1007/S11302-020-09715-0  0.434
2020 Han MAT, Vipani A, Noureddin N, Ramirez K, Gornbein J, Saouaf R, Baniesh N, Cummings-John O, Okubote T, Setiawan VW, Rotman Y, Loomba R, Alkhouri N, Noureddin M. MR Elastography-Based Liver Fibrosis Correlates with Liver Events in Nonalcoholic Fatty Liver Patients: A Multi-Center Study. Liver International : Official Journal of the International Association For the Study of the Liver. PMID 32652744 DOI: 10.1111/Liv.14593  0.445
2020 Pfeiffer RM, Rotman Y, O'Brien TR. Genetic Determinants of Cirrhosis and Hepatocellular Carcinoma Due to Fatty Liver Disease: What's the Score? Hepatology (Baltimore, Md.). PMID 32506469 DOI: 10.1002/Hep.31413  0.419
2020 Rotman Y, Kapuria D. Non‐alcoholic Fatty Liver Disease: Mechanisms and Treatment Liver. 670-681. DOI: 10.1002/9781119436812.Ch52  0.427
2019 Lai CW, Jadhav S, Njei B, Ye A, Wactawski-Wende J, Mumford SL, Schisterman EF, Rotman Y. Rhythmic Fluctuations in Levels of Liver Enzymes During Menstrual Cycles of Healthy Women and Effects of Body Weight. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 31811951 DOI: 10.1016/J.Cgh.2019.11.047  0.349
2019 Naguib G, Morris N, Yang S, Fryzek N, Haynes-Williams V, Huang WCA, Norman-Wheeler J, Rotman Y. Dietary Fatty Acid Oxidation is Decreased in Non-Alcoholic Fatty Liver Disease: A Palmitate Breath Test Study. Liver International : Official Journal of the International Association For the Study of the Liver. PMID 31762148 DOI: 10.1111/Liv.14309  0.4
2019 O'Donnell R, Jack-Roberts C, Killie N, Klatt K, Courville A, Schoenfeld M, Bernstein S, Zambell K, Morris N, Huang W, Rotman Y. A Multi-component Dietary Intervention to Reduce Weight and Liver Fat in NAFLD Patients Journal of the Academy of Nutrition and Dietetics. 119: A23. DOI: 10.1016/J.Jand.2019.06.085  0.356
2018 Ma Y, Belyaeva OV, Brown PM, Fujita K, Valles K, Karki S, de Boer YS, Koh C, Chen Y, Du X, Handelman SK, Chen V, Speliotes EK, Nestlerode C, Thomas E, ... ... Rotman Y, et al. HSD17B13 is a Hepatic Retinol Dehydrogenase Associated with Histological Features of Non-Alcoholic Fatty Liver Disease. Hepatology (Baltimore, Md.). PMID 30415504 DOI: 10.1002/Hep.30350  0.481
2018 Kim H, de Jesus AA, Brooks SR, Liu Y, Huang Y, VanTries R, Montealegre Sanchez GA, Rotman Y, Gadina M, Goldbach-Mansky R. Development of a Validated Interferon Score Using NanoString Technology. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 38: 171-185. PMID 29638206 DOI: 10.1089/Jir.2017.0127  0.345
2018 Rossi M, Zhu L, McMillin SM, Pydi SP, Jain S, Wang L, Cui Y, Lee RJ, Cohen AH, Kaneto H, Birnbaum MJ, Ma Y, Rotman Y, Liu J, Cyphert TJ, et al. Hepatic Gi signaling regulates whole-body glucose homeostasis. The Journal of Clinical Investigation. PMID 29337301 DOI: 10.1172/Jci94505  0.375
2018 O'MARA A, CYPESS A, CERO C, JOHNSON JW, LINDERMAN JD, LEITNER B, FLETCHER L, BRYCHTA R, KAPURIA D, MCGEHEE S, ROTMAN Y. Physiological Responses to Daily Use of Beta-Three Adrenergic Receptor Agonist, Mirabegron Diabetes. 67: 1146-P. DOI: 10.2337/Db18-1146-P  0.349
2018 Kapuria D, Ghomraoui F, Brown P, Ben-Yakov GS, Kleiner D, Rotman Y. Su1551 - Low Skeletal Muscle Mass is Associated with Advanced Steatosis in Non Alcoholic Fatty Liver Disease Gastroenterology. 154: S-1176. DOI: 10.1016/S0016-5085(18)33892-7  0.358
2017 Guber RD, Takyar V, Kokkinis A, Fox DA, Alao H, Kats I, Bakar D, Remaley AT, Hewitt SM, Kleiner DE, Liu CY, Hadigan C, Fischbeck KH, Rotman Y, Grunseich C. Nonalcoholic fatty liver disease in spinal and bulbar muscular atrophy. Neurology. PMID 29142082 DOI: 10.1212/Wnl.0000000000004748  0.371
2017 Takyar V, Nath A, Beri A, Gharib AM, Rotman Y. How healthy are the "healthy volunteers"? Penetrance of NAFLD in the biomedical research volunteer pool. Hepatology (Baltimore, Md.). PMID 28470683 DOI: 10.1002/Hep.29247  0.339
2017 Brown PM, Rotman Y. What if Prometheus had steatosis? Potential use of FGF19 to promote regeneration of the fatty liver. Gut. PMID 28274997 DOI: 10.1136/Gutjnl-2017-313712  0.45
2017 Takyar V, Etzion O, Heller T, Kleiner DE, Rotman Y, Ghany MG, Fryzek N, Williams VH, Rivera E, Auh S, Liang TJ, Hoofnagle JH, Koh C. Complications of percutaneous liver biopsy with Klatskin needles: a 36-year single-centre experience. Alimentary Pharmacology & Therapeutics. PMID 28074540 DOI: 10.1111/Apt.13939  0.471
2017 Koh C, Surana P, Han T, Fryzek N, Kapuria D, Etzion O, Takyar V, Rotman Y, Canales R, Dahari H, Yurdaydin C, Glenn J, Heller T. A phase 2 study exploring once daily dosing of ritonavir boosted lonafarnib for the treatment of chronic delta hepatitis – end of study results from the LOWR HDV-3 study Journal of Hepatology. 66: S101-S102. DOI: 10.1016/S0168-8278(17)30464-6  0.366
2017 Podszun MC, Rolt A, Garaffo M, Cai H, Alawad A, Morris N, Lingala S, Huang A, Gharib A, Walter P, Rotman Y. Vitamin E (RRR-α-tocopherol) decreases hepatic de novo lipogenesis Free Radical Biology and Medicine. 112: 30-31. DOI: 10.1016/J.Freeradbiomed.2017.10.035  0.737
2016 Rotman Y, Sanyal AJ. Current and upcoming pharmacotherapy for non-alcoholic fatty liver disease. Gut. PMID 27646933 DOI: 10.1136/Gutjnl-2016-312431  0.378
2015 Rotman Y. Comment on "Resveratrol improves insulin resistance, glucose and lipid metabolism in patients with non-alcoholic fatty liver disease: A randomized controlled trial" by Shihui Chen et al. [Dig. Liver Dis. 2015;47:226-32]. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 47: 1090. PMID 26382727 DOI: 10.1016/J.Dld.2015.08.011  0.394
2015 Rotman Y. Similarity between studies of dihydromyricetin and reservatrol for NAFLD. Pharmacological Research. 100: 335. PMID 26318761 DOI: 10.1016/J.Phrs.2015.07.034  0.385
2015 Noureddin M, Rotman Y, Zhang F, Park H, Rehermann B, Thomas E, Liang TJ. Hepatic expression levels of interferons and interferon-stimulated genes in patients with chronic hepatitis C: A phenotype-genotype correlation study. Genes and Immunity. 16: 321-9. PMID 26020282 DOI: 10.1038/Gene.2015.11  0.507
2015 Shimony MK, Schliep KC, Schisterman EF, Ahrens KA, Sjaarda LA, Rotman Y, Perkins NJ, Pollack AZ, Wactawski-Wende J, Mumford SL. The relationship between sugar-sweetened beverages and liver enzymes among healthy premenopausal women: a prospective cohort study. European Journal of Nutrition. PMID 25801628 DOI: 10.1007/S00394-015-0876-3  0.334
2015 Takyar V, Rotman Y, Zhao X, Ghany MG, Heller T, Doo E, Liang J, Hoofnagle J, Koh C. Sa1029 Retrospective Safety Analysis of Trainee-Performed Liver Biopsies at the National Institutes of Health Clinical Center - A 35-Year Experience Gastroenterology. 148: S-201. DOI: 10.1016/S0016-5085(15)30670-3  0.312
2014 Guedj J, Rotman Y, Cotler SJ, Koh C, Schmid P, Albrecht J, Haynes-Williams V, Liang TJ, Hoofnagle JH, Heller T, Dahari H. Understanding early serum hepatitis D virus and hepatitis B surface antigen kinetics during pegylated interferon-alpha therapy via mathematical modeling. Hepatology (Baltimore, Md.). 60: 1902-10. PMID 25098971 DOI: 10.1002/Hep.27357  0.455
2014 Heller T, Rotman Y, Koh C, Clark S, Haynes-Williams V, Chang R, McBurney R, Schmid P, Albrecht J, Kleiner DE, Ghany MG, Liang TJ, Hoofnagle JH. Long-term therapy of chronic delta hepatitis with peginterferon alfa. Alimentary Pharmacology & Therapeutics. 40: 93-104. PMID 24815494 DOI: 10.1111/Apt.12788  0.505
2014 Werner JM, Serti E, Chepa-Lotrea X, Stoltzfus J, Ahlenstiel G, Noureddin M, Feld JJ, Liang TJ, Rotman Y, Rehermann B. Ribavirin improves the IFN-γ response of natural killer cells to IFN-based therapy of hepatitis C virus infection. Hepatology (Baltimore, Md.). 60: 1160-9. PMID 24700342 DOI: 10.1002/Hep.27092  0.414
2014 Rotman Y, Noureddin M, Feld JJ, Guedj J, Witthaus M, Han H, Park YJ, Park SH, Heller T, Ghany MG, Doo E, Koh C, Abdalla A, Gara N, Sarkar S, et al. Effect of ribavirin on viral kinetics and liver gene expression in chronic hepatitis C. Gut. 63: 161-9. PMID 23396509 DOI: 10.1136/Gutjnl-2012-303852  0.537
2014 Han H, Noureddin M, Witthaus M, Park YJ, Hoofnagle JH, Liang TJ, Rotman Y. Corrigendum to “Temperature rise after peginterferon alfa-2a injection in patients with chronic hepatitis C is associated with virological response and is modulated by IL28B genotype” [J Hepatol 2013; 59:957–963] Journal of Hepatology. 60: 1334-1335. DOI: 10.1016/J.Jhep.2014.02.005  0.419
2013 Han H, Noureddin M, Witthaus M, Park YJ, Hoofnagle JH, Liang TJ, Rotman Y. Temperature rise after peginterferon alfa-2a injection in patients with chronic hepatitis C is associated with virological response and is modulated by IL28B genotype. Journal of Hepatology. 59: 957-63. PMID 23850879 DOI: 10.1016/J.Jhep.2013.07.004  0.464
2013 Koh C, Heller T, Haynes-Williams V, Hara K, Zhao X, Feld JJ, Kleiner DE, Rotman Y, Ghany MG, Liang TJ, Hoofnagle JH. Long-term outcome of chronic hepatitis C after sustained virological response to interferon-based therapy. Alimentary Pharmacology & Therapeutics. 37: 887-94. PMID 23461575 DOI: 10.1111/Apt.12273  0.439
2013 Njei B, Mumford SL, Ye A, Pollack AZ, Wactawski-Wende J, Schisterman EF, Rotman Y. Mo1027 Fluctuations of Liver Enzymes During the Menstrual Cycle Are Modulated by Obesity and Serum Lipids: the Biocycle Study Gastroenterology. 144: S-1016. DOI: 10.1016/S0016-5085(13)63773-7  0.302
2012 Ghany MG, Feld JJ, Zhao X, Heller T, Doo E, Rotman Y, Nagabhyru P, Koh C, Kleiner DE, Wright EC, Liang TJ, Hoofnagle JH. Randomised clinical trial: the benefit of combination therapy with adefovir and lamivudine for chronic hepatitis B. Alimentary Pharmacology & Therapeutics. 35: 1027-35. PMID 22449251 DOI: 10.1111/J.1365-2036.2012.05059.X  0.46
2012 Thomas E, Gonzalez VD, Li Q, Modi AA, Chen W, Noureddin M, Rotman Y, Liang TJ. HCV infection induces a unique hepatic innate immune response associated with robust production of type III interferons. Gastroenterology. 142: 978-88. PMID 22248663 DOI: 10.1053/J.Gastro.2011.12.055  0.454
2012 Edlich B, Ahlenstiel G, Zabaleta Azpiroz A, Stoltzfus J, Noureddin M, Serti E, Feld JJ, Liang TJ, Rotman Y, Rehermann B. Early changes in interferon signaling define natural killer cell response and refractoriness to interferon-based therapy of hepatitis C patients. Hepatology (Baltimore, Md.). 55: 39-48. PMID 21898483 DOI: 10.1002/Hep.24628  0.437
2011 Ahlenstiel G, Edlich B, Hogdal LJ, Rotman Y, Noureddin M, Feld JJ, Holz LE, Titerence RH, Liang TJ, Rehermann B. Early changes in natural killer cell function indicate virologic response to interferon therapy for hepatitis C. Gastroenterology. 141: 1231-9, 1239.e1-2. PMID 21741920 DOI: 10.1053/J.Gastro.2011.06.069  0.459
2011 Feld JJ, Modi AA, El-Diwany R, Rotman Y, Thomas E, Ahlenstiel G, Titerence R, Koh C, Cherepanov V, Heller T, Ghany MG, Park Y, Hoofnagle JH, Liang TJ. S-adenosyl methionine improves early viral responses and interferon-stimulated gene induction in hepatitis C nonresponders. Gastroenterology. 140: 830-9. PMID 20854821 DOI: 10.1053/J.Gastro.2010.09.010  0.464
2011 Thomas E, Gonzalez VD, Li Q, Modi AA, Uccellini L, Thomas JM, Chen W, Noureddin M, Rotman Y, Liang TJ. PS1-125 A robust induction of type III interferons and chemokines defines a unique pattern of hepatic innate immunity in response to hepatitis C virus infection Cytokine. 56: 49. DOI: 10.1016/J.Cyto.2011.07.158  0.473
2010 Rotman Y, Koh C, Zmuda JM, Kleiner DE, Liang TJ. The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease. Hepatology (Baltimore, Md.). 52: 894-903. PMID 20684021 DOI: 10.1002/Hep.23759  0.432
2010 Feld JJ, Lutchman GA, Heller T, Hara K, Pfeiffer JK, Leff RD, Meek C, Rivera M, Ko M, Koh C, Rotman Y, Ghany MG, Haynes-Williams V, Neumann AU, Liang TJ, et al. Ribavirin improves early responses to peginterferon through improved interferon signaling. Gastroenterology. 139: 154-62.e4. PMID 20303352 DOI: 10.1053/J.Gastro.2010.03.037  0.465
2010 Rotman Y, Borg BB, Soza A, Feld JJ, Modi AA, Loomba R, Lutchman G, Rivera E, Doo E, Ghany MG, Heller T, Neumann AU, Liang TJ, Hoofnagle JH. Low- and standard-dose peginterferon alfa-2a for chronic hepatitis C, genotype 2 or 3: efficacy, tolerability, viral kinetics and cytokine response. Alimentary Pharmacology & Therapeutics. 31: 1018-27. PMID 20163377 DOI: 10.1111/J.1365-2036.2010.04263.X  0.389
2010 Ahlenstiel G, Titerence RH, Koh C, Edlich B, Feld JJ, Rotman Y, Ghany MG, Hoofnagle JH, Liang TJ, Heller T, Rehermann B. Natural killer cells are polarized toward cytotoxicity in chronic hepatitis C in an interferon-alfa-dependent manner. Gastroenterology. 138: 325-35.e1-2. PMID 19747917 DOI: 10.1053/J.Gastro.2009.08.066  0.483
2009 Rotman Y, Liang TJ. Coinfection with hepatitis C virus and human immunodeficiency virus: virological, immunological, and clinical outcomes. Journal of Virology. 83: 7366-74. PMID 19420073 DOI: 10.1128/Jvi.00191-09  0.441
2009 Rotman Y, Brown TA, Hoofnagle JH. Evaluation of the patient with hepatitis B. Hepatology (Baltimore, Md.). 49: S22-7. PMID 19399815 DOI: 10.1002/Hep.22976  0.361
2009 Rotman Y, Katz L, Cohen M, Cohen-Ezra O, Manhaim V, Braun M, Ben-Ari Z, Tur-Kaspa R. Low weight predicts neutropenia and peginterferon alfa-2a dose reductions during treatment for chronic hepatitis C. Journal of Viral Hepatitis. 16: 340-345. PMID 19220735 DOI: 10.1111/J.1365-2893.2009.01079.X  0.332
2008 Schmilovitz-Weiss H, Niv Y, Pappo O, Halpern M, Sulkes J, Braun M, Barak N, Rotman Y, Cohen M, Waked A, Tur-Kaspa R, Ben-Ari Z. The 13C-caffeine breath test detects significant fibrosis in patients with nonalcoholic steatohepatitis. Journal of Clinical Gastroenterology. 42: 408-12. PMID 18277896 DOI: 10.1097/Mcg.0B013E318046Ea65  0.401
2007 Cohen M, Bachmatov L, Ben-Ari Z, Rotman Y, Tur-Kaspa R, Zemel R. Development of specific antibodies to an ARF protein in treated patients with chronic HCV infection Digestive Diseases and Sciences. 52: 2427-2432. PMID 17436105 DOI: 10.1007/S10620-006-9630-2  0.301
2007 Rotman Y, Ghany MG. INTERFERON-?? FOR HEPATIC FIBROSIS IN PATIENTS WITH CHRONIC HEPATITIS C Evidence-Based Gastroenterology. 8: 61-63. DOI: 10.1097/Ebg.0B013E3181462C77  0.461
2006 Schmilovitz-Weiss H, Tovar A, Halpern M, Sulkes J, Braun M, Rotman Y, Tur-Kaspa R, Ben-Ari Z. Predictive value of serum globulin levels for the extent of hepatic fibrosis in patients with chronic hepatitis B infection. Journal of Viral Hepatitis. 13: 671-7. PMID 16970598 DOI: 10.1111/J.1365-2893.2006.00744.X  0.434
2006 Braun M, Pappot O, Zuckerman E, Sulkes J, Kitai Y, Moreno M, Cohen O, Shmilovitz-Weiss H, Rotman Y, Zamirs D, Melnik S, Tur-Kaspa R, Ben-Ari Z. 674 The innovative real time Breath-ID® test system diagnoses and predicts the extent of hepatic injury in patients with non-alcoholic fatty liver disease Journal of Hepatology. 44: S249. DOI: 10.1016/S0168-8278(06)80674-4  0.424
2006 Rotman Y, Levi Z, Hazazi R, Cohen M, Cohen-Ezra O, Manhaim V, Braun M, Ben-Ari Z, Tur-Kaspa R. 604 Serum lipoprotein levels during treatment of chronic hepatitis C with Peg-interferon-alpha-2a & ribavirin — a differential effect on genotype 3 patients Journal of Hepatology. 44: S224. DOI: 10.1016/S0168-8278(06)80604-5  0.378
2003 ZEMEL R, BARAK N, BACHMATOVE L, DRORI R, ROTMAN Y, TURKASPA R. 631 Augmentation of PPAR-alpha expression induced by hepatitis C virus core protein Hepatology. 38: 465-465. DOI: 10.1016/S0270-9139(03)80673-0  0.33
2002 Bar-Yosef O, Rotman Y, Nelken I. Responses of neurons in cat primary auditory cortex to bird chirps: effects of temporal and spectral context. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8619-32. PMID 12351736 DOI: 10.1523/Jneurosci.22-19-08619.2002  0.544
2001 Rotman Y, Bar-Yosef O, Nelken I. Relating cluster and population responses to natural sounds and tonal stimuli in cat primary auditory cortex. Hearing Research. 152: 110-27. PMID 11223286 DOI: 10.1016/S0378-5955(00)00243-4  0.55
1999 Nelken I, Rotman Y, Bar Yosef O. Responses of auditory-cortex neurons to structural features of natural sounds. Nature. 397: 154-7. PMID 9923676 DOI: 10.1038/16456  0.531
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