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Alexander M Xu - Publications

Affiliations: 
Institute for Systems Biology, Seattle, WA, United States 
Area:
Single Cell Analysis, Nanotechnology, Drug Delivery, Transcriptomics, Sequencing
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Chour W, Choi J, Xie J, Chaffee ME, Schmitt TM, Finton K, DeLucia DC, Xu AM, Su Y, Chen DG, Zhang R, Yuan D, Hong S, Ng AHC, Butler JZ, et al. Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis. Communications Biology. 6: 528. PMID 37193826 DOI: 10.1038/s42003-023-04899-8  0.757
2023 Xu AM, Chour W, DeLucia DC, Su Y, Pavlovitch-Bedzyk AJ, Ng R, Rasheed Y, Davis MM, Lee JK, Heath JR. Entropic analysis of antigen-specific CDR3 domains identifies essential binding motifs shared by CDR3s with different antigen specificities. Cell Systems. PMID 37001518 DOI: 10.1016/j.cels.2023.03.001  0.74
2022 Heath J, Chour W, Choi J, Xie J, Chaffee M, Schmitt T, Finton K, Delucia D, Xu A, Su Y, Chen D, Zhang R, Yuan D, Hong S, Ng A, et al. Large libraries of single-chain trimer peptide-MHCs enable rapid antigen-specific CD8+ T cell discovery and analysis. Research Square. PMID 36415462 DOI: 10.21203/rs.3.rs-1090664/v1  0.721
2020 Su Y, Ko ME, Cheng H, Zhu R, Xue M, Wang J, Lee JW, Frankiw L, Xu A, Wong S, Robert L, Takata K, Yuan D, Lu Y, Huang S, et al. Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line. Nature Communications. 11: 2345. PMID 32393797 DOI: 10.1038/S41467-020-15956-9  0.777
2020 He G, Hu N, Xu AM, Li X, Zhao Y, Xie X. Nanoneedle Platforms: The Many Ways to Pierce the Cell Membrane Advanced Functional Materials. 30: 1909890. DOI: 10.1002/Adfm.201909890  0.453
2019 Ng AHC, Peng S, Xu AM, Noh WJ, Guo K, Bethune MT, Chour W, Choi J, Yang S, Baltimore D, Heath JR. MATE-Seq: microfluidic antigen-TCR engagement sequencing. Lab On a Chip. 19: 3011-3021. PMID 31502632 DOI: 10.1039/C9Lc00538B  0.7
2019 Peng S, Zaretsky JM, Ng AHC, Chour W, Bethune MT, Choi J, Hsu A, Holman E, Ding X, Guo K, Kim J, Xu AM, Heath JE, Noh WJ, Zhou J, et al. Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood. Cell Reports. 28: 2728-2738.e7. PMID 31484081 DOI: 10.1016/J.Celrep.2019.07.106  0.774
2018 Xu AM, Liu Q, Takata KL, Jeoung S, Su Y, Antoshechkin I, Chen S, Thomson M, Heath JR. Integrated measurement of intracellular proteins and transcripts in single cells. Lab On a Chip. PMID 30178802 DOI: 10.1039/C8Lc00639C  0.774
2017 Sander J, Schmidt SV, Cirovic B, McGovern N, Papantonopoulou O, Hardt AL, Aschenbrenner AC, Kreer C, Quast T, Xu AM, Schmidleithner LM, Theis H, Thi Huong LD, Sumatoh HRB, Lauterbach MAR, et al. Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2. Immunity. 47: 1051-1066.e12. PMID 29262348 DOI: 10.1016/J.Immuni.2017.11.024  0.672
2017 Xu AM, Wang DS, Shieh P, Cao Y, Melosh N. Direct Intracellular Delivery of Cell Impermeable Probes of Protein Glycosylation Using Nanostraws. Chembiochem : a European Journal of Chemical Biology. PMID 28130882 DOI: 10.1002/Cbic.201600689  0.764
2016 Xu AM, Kim SA, Wang DS, Aalipour A, Melosh NA. Temporally resolved direct delivery of second messengers into cells using nanostraws. Lab On a Chip. PMID 27292263 DOI: 10.1039/C6Lc00463F  0.766
2016 Fox CB, Cao Y, Nemeth CL, Chirra HD, Chevalier RW, Xu AM, Melosh NA, Desai TA. Fabrication of Sealed Nanostraw Microdevices for Oral Drug Delivery. Acs Nano. PMID 27268699 DOI: 10.1021/Acsnano.6B00809  0.678
2015 Xu A, Shieh P, Sanman L, Melosh N. Nanostraws: A Nanofabricated Platform for Delivery of Cell-Impermeable, Synthetic Biomolecules Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.823  0.759
2015 Xu A, Aalipour A, Kim S, Melosh N. Bioorthogonal Calcium Modulation by Direct Intracellular Access using Nanostraws Biophysical Journal. 108: 568a. DOI: 10.1016/J.Bpj.2014.11.3109  0.706
2014 Aalipour A, Xu AM, Leal-Ortiz S, Garner CC, Melosh NA. Plasma membrane and actin cytoskeleton as synergistic barriers to nanowire cell penetration. Langmuir : the Acs Journal of Surfaces and Colloids. 30: 12362-7. PMID 25244597 DOI: 10.1021/La502273F  0.719
2014 Xu AM, Aalipour A, Leal-Ortiz S, Mekhdjian AH, Xie X, Dunn AR, Garner CC, Melosh NA. Quantification of nanowire penetration into living cells. Nature Communications. 5: 3613. PMID 24710350 DOI: 10.1038/Ncomms4613  0.753
2014 Xu A, Kim SA, Aalipour A, Melosh NA. Rapid Calcium Modulation in Cells: Direct Intracellular Access using Nanostraws Biophysical Journal. 106: 432a. DOI: 10.1016/J.Bpj.2013.11.2431  0.689
2013 Xie X, Xu AM, Angle MR, Tayebi N, Verma P, Melosh NA. Mechanical model of vertical nanowire cell penetration. Nano Letters. 13: 6002-8. PMID 24237230 DOI: 10.1021/Nl403201A  0.776
2013 Xie X, Xu AM, Leal-Ortiz S, Cao Y, Garner CC, Melosh NA. Nanostraw-electroporation system for highly efficient intracellular delivery and transfection. Acs Nano. 7: 4351-8. PMID 23597131 DOI: 10.1021/Nn400874A  0.732
2013 Xu AM, Aalipour A, Melosh NA. Nanostraw-Mediated Intracellular Delivery: Direct Observation of Cell/Nanotube Interfaces Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.1092  0.748
2012 Smith BR, Kempen P, Bouley D, Xu A, Liu Z, Melosh N, Dai H, Sinclair R, Gambhir SS. Shape matters: intravital microscopy reveals surprising geometrical dependence for nanoparticles in tumor models of extravasation. Nano Letters. 12: 3369-77. PMID 22650417 DOI: 10.1021/Nl204175T  0.666
2012 VanDersarl JJ, Xu AM, Melosh NA. Nanostraws for direct fluidic intracellular access. Nano Letters. 12: 3881-6. PMID 22166016 DOI: 10.1021/Nl204051V  0.762
2011 VanDersarl JJ, Xu AM, Melosh NA. Rapid spatial and temporal controlled signal delivery over large cell culture areas. Lab On a Chip. 11: 3057-63. PMID 21805010 DOI: 10.1039/C1Lc20311H  0.723
2010 Huang PH, Miraldi ER, Xu AM, Kundukulam VA, Del Rosario AM, Flynn RA, Cavenee WK, Furnari FB, White FM. Phosphotyrosine signaling analysis of site-specific mutations on EGFRvIII identifies determinants governing glioblastoma cell growth. Molecular Biosystems. 6: 1227-37. PMID 20461251 DOI: 10.1039/C001196G  0.317
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