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Qingfei Zheng, Ph.D. - Publications

Affiliations: 
2008-2012 Chemistry Tsinghua University, Beijing, China, Beijing, Beijing Shi, China 
 2012-2017 State Key Laboratory of Bioorganic and Natural Products Chemistry Shanghai institute of Organic Chemistry, CAS 
 2017-2021 Chemical Biology Program Memorial Sloan Kettering Cancer Center, Rockville Centre, NY, United States 
 2021- Department of Radiation Oncology The Ohio State University College of Medicine 
Area:
Cancer Metabolism, Epigenetics, Chemical Biology, Synthetic Biology, Microbiology, Drug Discovery
Website:
https://www.linkedin.com/in/qingfei-zheng-b574b32a/
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Zheng Q, Osunsade A, David Y. Protein arginine deiminase 4 antagonizes methylglyoxal-induced histone glycation. Nature Communications. 11: 3241. PMID 32591537 DOI: 10.1038/S41467-020-17066-Y  0.706
2020 Maksimovic I, Zheng Q, Trujillo MN, Galligan JJ, David Y. An Azidoribose Probe to Track Ketoamine Adducts in Histone Ribose Glycation. Journal of the American Chemical Society. PMID 32390412 DOI: 10.1021/Jacs.0C01325  0.696
2020 Zheng Q, Maksimovic I, Upad A, David Y. Non-enzymatic covalent modifications: a new link between metabolism and epigenetics. Protein & Cell. PMID 32356279 DOI: 10.1007/S13238-020-00722-W  0.701
2019 Zheng Q, Maksimovic I, Upad A, Guber D, David Y. Synthesis of an Alkynyl Methylglyoxal Probe to Investigate Non-enzymatic Histone Glycation. The Journal of Organic Chemistry. PMID 31875401 DOI: 10.1021/Acs.Joc.9B02504  0.701
2019 Maksimovic I, Ray D, Zheng Q, David Y. Utilizing intein trans-splicing for in vivo generation of site-specifically modified proteins. Methods in Enzymology. 626: 203-222. PMID 31606075 DOI: 10.1016/Bs.Mie.2019.07.015  0.674
2019 Liu J, Lin Z, Li Y, Zheng Q, Chen D, Liu W. Insights into the thioamidation of thiopeptins to enhance the understanding of the biosynthetic logic of thioamide-containing thiopeptides. Organic & Biomolecular Chemistry. PMID 30912568 DOI: 10.1039/C9Ob00402E  0.423
2019 Zheng Q, Omans ND, Leicher R, Osunsade A, Agustinus AS, Finkin-Groner E, D'Ambrosio H, Liu B, Chandarlapaty S, Liu S, David Y. Reversible histone glycation is associated with disease-related changes in chromatin architecture. Nature Communications. 10: 1289. PMID 30894531 DOI: 10.1038/S41467-019-09192-Z  0.71
2019 Zheng Q, Prescott NA, Maksimovic I, David Y. (de)Toxifying the Epigenetic Code. Chemical Research in Toxicology. PMID 30839196 DOI: 10.1021/Acs.Chemrestox.9B00013  0.715
2018 Zheng Q, Gong Y, Guo Y, Zhao Z, Wu Z, Zhou Z, Chen D, Pan L, Liu W. Structural Insights into a Flavin-Dependent [4 + 2] Cyclase that Catalyzes trans-Decalin Formation in Pyrroindomycin Biosynthesis. Cell Chemical Biology. PMID 29657086 DOI: 10.1016/J.Chembiol.2018.03.007  0.384
2017 Li X, Zheng Q, Yin J, Liu W, Gao S. Chemo-enzymatic synthesis of equisetin. Chemical Communications (Cambridge, England). PMID 28401214 DOI: 10.1039/C7Cc01929G  0.456
2017 Zheng Q, Fang H, Liu W. Post-translational modifications involved in the biosynthesis of thiopeptide antibiotics. Organic & Biomolecular Chemistry. PMID 28358161 DOI: 10.1039/C7Ob00466D  0.505
2016 Zheng Q, Wu Z, Sun P, Chen D, Tian Z, Liu W. A linear hydroxymethyl tetramate undergoes an acetylation-elimination process for exocyclic methylene formation in the biosynthetic pathway of pyrroindomycins. Organic & Biomolecular Chemistry. PMID 27942669 DOI: 10.1039/C6Ob02567F  0.441
2016 Zheng Q, Wang S, Duan P, Liao R, Chen D, Liu W. An α/β-hydrolase fold protein in the biosynthesis of thiostrepton exhibits a dual activity for endopeptidyl hydrolysis and epoxide ring opening/macrocyclization. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911800 DOI: 10.1073/Pnas.1612607113  0.499
2016 Zheng Q, Wang S, Liao R, Liu W. Precursor-directed Mutational Biosynthesis Facilitates the Functional Assignment of Two Cytochromes P450 in Thiostrepton Biosynthesis. Acs Chemical Biology. PMID 27560135 DOI: 10.1021/Acschembio.6B00419  0.433
2016 Zheng Q, Guo Y, Yang L, Zhao Z, Wu Z, Zhang H, Liu J, Cheng X, Wu J, Yang H, Jiang H, Pan L, Liu W. Enzyme-Dependent [4 + 2] Cycloaddition Depends on Lid-like Interaction of the N-Terminal Sequence with the Catalytic Core in PyrI4. Cell Chemical Biology. PMID 26877021 DOI: 10.1016/J.Chembiol.2016.01.005  0.461
2016 Zheng Q, Tian Z, Liu W. Recent advances in understanding the enzymatic reactions of [4+2] cycloaddition and spiroketalization. Current Opinion in Chemical Biology. 31: 95-102. PMID 26870924 DOI: 10.1016/J.Cbpa.2016.01.020  0.462
2016 Zheng Q, Liu W. Thiopeptide Antibiotics act on both Host and Microbe to Deliver Double Punch on Mycobacterial Infection Mycobacterial Diseases. 6: 1-3. DOI: 10.4172/2161-1068.1000203  0.365
2016 Duan P, Zheng Q, Lin Z, Wang S, Chen D, Liu W. Molecular engineering of thiostrepton: Via single "base"-based mutagenesis to generate side ring-derived variants Organic Chemistry Frontiers. 3: 1254-1258. DOI: 10.1039/C6Qo00320F  0.429
2016 Wang S, Zheng Q, Wang J, Chen D, Yu Y, Liu W. Concurrent modifications of the C-terminus and side ring of thiostrepton and their synergistic effects with respect to improving antibacterial activities Organic Chemistry Frontiers. 3: 496-500. DOI: 10.1039/C5Qo00433K  0.454
2015 Zhang L, Mori T, Zheng Q, Awakawa T, Yan Y, Liu W, Abe I. Rational Control of Polyketide Extender Units by Structure-Based Engineering of a Crotonyl-CoA Carboxylase/Reductase in Antimycin Biosynthesis. Angewandte Chemie (International Ed. in English). PMID 26356484 DOI: 10.1002/Anie.201506899  0.453
2015 Zheng Q, Wang Q, Wang S, Wu J, Gao Q, Liu W. Thiopeptide Antibiotics Exhibit a Dual Mode of Action against Intracellular Pathogens by Affecting Both Host and Microbe. Chemistry & Biology. PMID 26211364 DOI: 10.1016/J.Chembiol.2015.06.019  0.402
2015 Tian Z, Sun P, Yan Y, Wu Z, Zheng Q, Zhou S, Zhang H, Yu F, Jia X, Chen D, Mándi A, Kurtán T, Liu W. An enzymatic [4+2] cyclization cascade creates the pentacyclic core of pyrroindomycins. Nature Chemical Biology. 11: 259-65. PMID 25730548 DOI: 10.1038/Nchembio.1769  0.493
2015 Wang S, Zheng Q, Wang J, Zhao Z, Li Q, Yu Y, Wang R, Liu W. Target-oriented design and biosynthesis of thiostrepton-derived thiopeptide antibiotics with improved pharmaceutical properties Organic Chemistry Frontiers. 2: 106-109. DOI: 10.1039/C4Qo00288A  0.414
2014 Guo H, Wang J, Li Y, Yu Y, Zheng Q, Wu J, Liu W. Insight into bicyclic thiopeptide biosynthesis benefited from development of a uniform approach for molecular engineering and production improvement Chemical Science. 5: 240-246. DOI: 10.1039/C3Sc52015C  0.47
2014 Zheng Q, Wang S, Liu W. Discovery and efficient synthesis of a biologically active alkaloid inspired by thiostrepton biosynthesis Tetrahedron. 70: 7686-7690. DOI: 10.1016/J.Tet.2014.06.076  0.446
2013 Yan Y, Chen J, Zhang L, Zheng Q, Han Y, Zhang H, Zhang D, Awakawa T, Abe I, Liu W. Multiplexing of combinatorial chemistry in antimycin biosynthesis: Expansion of molecular diversity and utility Angewandte Chemie - International Edition. 52: 12308-12312. PMID 24123503 DOI: 10.1002/Anie.201305569  0.416
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