| Year |
Citation |
Score |
| 2019 |
Takeshita N, Kawade N, Suzuki W, Hara S, Horio F, Ichinose H. Deficiency of ascorbic acid decreases the contents of tetrahydrobiopterin in the liver and the brain of ODS rats. Neuroscience Letters. 715: 134656. PMID 31794791 DOI: 10.1016/J.Neulet.2019.134656 |
0.303 |
|
| 2019 |
Miramontes-Gonzalez JP, Hightower M, Zhang K, Kurosaki H, Schork AJ, Biswas N, Vaingankar S, Mahata M, Lipkowitz MS, Nievergelt CM, Baker DG, Ziegler MG, León-Jiménez D, González-Sarmiento R, Ichinose H, et al. A new common functional coding variant at the DDC gene change renal enzyme activity and modify renal dopamine function. Scientific Reports. 9: 5055. PMID 30911067 DOI: 10.1038/S41598-019-41504-7 |
0.318 |
|
| 2019 |
Kurosaki H, Yamaguchi K, Man-Yoshi K, Muramatsu SI, Hara S, Ichinose H. Administration of tetrahydrobiopterin restored the decline of dopamine in the striatum induced by an acute action of MPTP. Neurochemistry International. 125: 16-24. PMID 30739038 DOI: 10.1016/J.Neuint.2019.02.005 |
0.382 |
|
| 2018 |
Nagatsu T, Nakashima A, Ichinose H, Kobayashi K. Human tyrosine hydroxylase in Parkinson's disease and in related disorders. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 29995172 DOI: 10.1007/S00702-018-1903-3 |
0.371 |
|
| 2016 |
Ishikawa T, Imamura K, Kondo T, Koshiba Y, Hara S, Ichinose H, Furujo M, Kinoshita M, Oeda T, Takahashi J, Takahashi R, Inoue H. Genetic and pharmacological correction of aberrant dopamine synthesis using patient iPSCs with BH4 metabolism disorders. Human Molecular Genetics. PMID 27798097 DOI: 10.1093/Hmg/Ddw339 |
0.338 |
|
| 2015 |
Kawahata I, Ohtaku S, Tomioka Y, Ichinose H, Yamakuni T. Dopamine or biopterin deficiency potentiates phosphorylation at (40)Ser and ubiquitination of tyrosine hydroxylase to be degraded by the ubiquitin proteasome system. Biochemical and Biophysical Research Communications. 465: 53-8. PMID 26225746 DOI: 10.1016/J.Bbrc.2015.07.125 |
0.375 |
|
| 2014 |
Horiguchi M, Ohi K, Hashimoto R, Hao Q, Yasuda Y, Yamamori H, Fujimoto M, Umeda-Yano S, Takeda M, Ichinose H. Functional polymorphism (C-824T) of the tyrosine hydroxylase gene affects IQ in schizophrenia. Psychiatry and Clinical Neurosciences. 68: 456-62. PMID 24417771 DOI: 10.1111/Pcn.12157 |
0.32 |
|
| 2013 |
Liang Y, Inagaki H, Hao Q, Sakamoto M, Ohye T, Suzuki T, Ichinose H. Identification of an enhancer region for immune activation in the human GTP cyclohydrolase I gene. Biochemical and Biophysical Research Communications. 442: 72-8. PMID 24220333 DOI: 10.1016/J.Bbrc.2013.11.002 |
0.306 |
|
| 2013 |
Armata IA, Balaj L, Kuster JK, Zhang X, Tsai S, Armatas AA, Multhaupt-Buell TJ, Soberman R, Breakefield XO, Ichinose H, Sharma N. Dopa-responsive dystonia: functional analysis of single nucleotide substitutions within the 5' untranslated GCH1 region. Plos One. 8: e76975. PMID 24124602 DOI: 10.1371/Journal.Pone.0076975 |
0.327 |
|
| 2013 |
Hwu WL, Lee NC, Chien YH, Muramatsu S, Ichinose H. AADC deficiency: occurring in humans, modeled in rodents. Advances in Pharmacology (San Diego, Calif.). 68: 273-84. PMID 24054149 DOI: 10.1016/B978-0-12-411512-5.00013-0 |
0.345 |
|
| 2013 |
Ichinose H, Homma D, Sumi-Ichinose C, Nomura T, Kondo K. GTP cyclohydrolase regulation: implications for brain development and function. Advances in Pharmacology (San Diego, Calif.). 68: 23-35. PMID 24054139 DOI: 10.1016/B978-0-12-411512-5.00003-8 |
0.375 |
|
| 2013 |
Homma D, Katoh S, Tokuoka H, Ichinose H. The role of tetrahydrobiopterin and catecholamines in the developmental regulation of tyrosine hydroxylase level in the brain. Journal of Neurochemistry. 126: 70-81. PMID 23647001 DOI: 10.1111/Jnc.12287 |
0.363 |
|
| 2013 |
Lee NC, Shieh YD, Chien YH, Tzen KY, Yu IS, Chen PW, Hu MH, Hu MK, Muramatsu S, Ichinose H, Hwu WL. Regulation of the dopaminergic system in a murine model of aromatic L-amino acid decarboxylase deficiency. Neurobiology of Disease. 52: 177-90. PMID 23275025 DOI: 10.1016/J.Nbd.2012.12.005 |
0.344 |
|
| 2012 |
Kanao T, Sawada T, Davies SA, Ichinose H, Hasegawa K, Takahashi R, Hattori N, Imai Y. The nitric oxide-cyclic GMP pathway regulates FoxO and alters dopaminergic neuron survival in Drosophila. Plos One. 7: e30958. PMID 22393355 DOI: 10.1371/Journal.Pone.0030958 |
0.354 |
|
| 2012 |
Yagi H, Sanechika S, Ichinose H, Sumi-Ichinose C, Mizukami H, Urabe M, Ozawa K, Kume A. Recovery of neurogenic amines in phenylketonuria mice after liver-targeted gene therapy. Neuroreport. 23: 30-4. PMID 22107842 DOI: 10.1097/Wnr.0B013E32834E3A87 |
0.33 |
|
| 2011 |
Tokuoka H, Muramatsu S, Sumi-Ichinose C, Sakane H, Kojima M, Aso Y, Nomura T, Metzger D, Ichinose H. Compensatory regulation of dopamine after ablation of the tyrosine hydroxylase gene in the nigrostriatal projection. The Journal of Biological Chemistry. 286: 43549-58. PMID 22027820 DOI: 10.1074/Jbc.M111.284729 |
0.55 |
|
| 2011 |
Homma D, Sumi-Ichinose C, Tokuoka H, Ikemoto K, Nomura T, Kondo K, Katoh S, Ichinose H. Partial biopterin deficiency disturbs postnatal development of the dopaminergic system in the brain. The Journal of Biological Chemistry. 286: 1445-52. PMID 21062748 DOI: 10.1074/Jbc.M110.159426 |
0.35 |
|
| 2010 |
Fukuchi M, Fujii H, Takachi H, Ichinose H, Kuwana Y, Tabuchi A, Tsuda M. Activation of tyrosine hydroxylase (TH) gene transcription induced by brain-derived neurotrophic factor (BDNF) and its selective inhibition through Ca(2+) signals evoked via the N-methyl-D-aspartate (NMDA) receptor. Brain Research. 1366: 18-26. PMID 20965158 DOI: 10.1016/J.Brainres.2010.10.034 |
0.326 |
|
| 2010 |
Sumi-Ichinose C, Ichinose H, Ikemoto K, Nomura T, Kondo K. Advanced research on dopamine signaling to develop drugs for the treatment of mental disorders: regulation of dopaminergic neural transmission by tyrosine hydroxylase protein at nerve terminals. Journal of Pharmacological Sciences. 114: 17-24. PMID 20716859 DOI: 10.1254/Jphs.09R28Fm |
0.363 |
|
| 2010 |
Homma D, Tokuoka H, Katoh S, Ichinose H. Alterations in the monoamines and the synthesizing enzymes in the postnatal developmental period of the brain of Spr-/- mice Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.129 |
0.305 |
|
| 2009 |
Kadkhodaei B, Ito T, Joodmardi E, Mattsson B, Rouillard C, Carta M, Muramatsu S, Sumi-Ichinose C, Nomura T, Metzger D, Chambon P, Lindqvist E, Larsson NG, Olson L, Björklund A, ... Ichinose H, et al. Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 15923-32. PMID 20016108 DOI: 10.1523/Jneurosci.3910-09.2009 |
0.345 |
|
| 2009 |
Kawahata I, Tokuoka H, Parvez H, Ichinose H. Accumulation of phosphorylated tyrosine hydroxylase into insoluble protein aggregates by inhibition of an ubiquitin-proteasome system in PC12D cells. Journal of Neural Transmission (Vienna, Austria : 1996). 116: 1571-8. PMID 19756365 DOI: 10.1007/S00702-009-0304-Z |
0.351 |
|
| 2009 |
Ichinose H, Kawahata I, Homma D. Regulation of dopamine synthesis by alteration in the TH protein level Neuroscience Research. 65. DOI: 10.1016/J.Neures.2009.09.1623 |
0.334 |
|
| 2009 |
Tokuoka H, Ichinose H. Homeostasis of nigro-striatal dopaminergic projection – compensatory regulation of tyrosine hydroxylase and dopamine content Neuroscience Research. 65. DOI: 10.1016/J.Neures.2009.09.1548 |
0.311 |
|
| 2008 |
Ichinose H, Nomura T, Sumi-Ichinose C. Metabolism of tetrahydrobiopterin: its relevance in monoaminergic neurons and neurological disorders. Chemical Record (New York, N.Y.). 8: 378-85. PMID 19107867 DOI: 10.1002/Tcr.20166 |
0.369 |
|
| 2008 |
Yamasaki N, Maekawa M, Kobayashi K, Kajii Y, Maeda J, Soma M, Takao K, Tanda K, Ohira K, Toyama K, Kanzaki K, Fukunaga K, Sudo Y, Ichinose H, Ikeda M, et al. Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders. Molecular Brain. 1: 6. PMID 18803808 DOI: 10.1186/1756-6606-1-6 |
0.317 |
|
| 2008 |
Sato K, Sumi-Ichinose C, Kaji R, Ikemoto K, Nomura T, Nagatsu I, Ichinose H, Ito M, Sako W, Nagahiro S, Graybiel AM, Goto S. Differential involvement of striosome and matrix dopamine systems in a transgenic model of dopa-responsive dystonia. Proceedings of the National Academy of Sciences of the United States of America. 105: 12551-6. PMID 18713855 DOI: 10.1073/Pnas.0806065105 |
0.373 |
|
| 2008 |
Takazawa C, Fujimoto K, Homma D, Sumi-Ichinose C, Nomura T, Ichinose H, Katoh S. A brain-specific decrease of the tyrosine hydroxylase protein in sepiapterin reductase-null mice--as a mouse model for Parkinson's disease. Biochemical and Biophysical Research Communications. 367: 787-92. PMID 18201550 DOI: 10.1016/J.Bbrc.2008.01.028 |
0.351 |
|
| 2008 |
Kojima M, Suzuki T, Maekawa T, Ishii S, Sumi-Ichinose C, Nomura T, Ichinose H. Increased expression of tyrosine hydroxylase and anomalous neurites in catecholaminergic neurons of ATF-2 null mice. Journal of Neuroscience Research. 86: 544-52. PMID 17896792 DOI: 10.1002/Jnr.21510 |
0.376 |
|
| 2007 |
Sakane H, Sumi-Ichinose C, Kojima M, Aso Y, Muramatsu S, Nakano I, Ozawa K, Nomura T, Nagatsu I, Nagatsu T, Metzger D, Chambon P, Ichinose H. Delayed reduction of the protein level in the striatum after genetic ablation of the tyrosine hydroxylase gene in the substantia nigra Neuroscience Research. 58. DOI: 10.1016/J.Neures.2007.06.1378 |
0.318 |
|
| 2006 |
Ohta E, Funayama M, Ichinose H, Toyoshima I, Urano F, Matsuo M, Tomoko N, Yukihiko K, Yoshino S, Yokoyama H, Shimazu H, Maeda K, Hasegawa K, Obata F. Novel mutations in the guanosine triphosphate cyclohydrolase 1 gene associated with DYT5 dystonia. Archives of Neurology. 63: 1605-10. PMID 17101830 DOI: 10.1001/Archneur.63.11.1605 |
0.307 |
|
| 2006 |
Urano F, Hayashi N, Arisaka F, Kurita H, Murata S, Ichinose H. Molecular mechanism for pterin-mediated inactivation of tyrosine hydroxylase: formation of insoluble aggregates of tyrosine hydroxylase. Journal of Biochemistry. 139: 625-35. PMID 16672262 DOI: 10.1093/Jb/Mvj073 |
0.353 |
|
| 2006 |
Ogawa S, Ichinose H. Effect of metals and phenylalanine on the activity of human tryptophan hydroxylase-2: comparison with that on tyrosine hydroxylase activity. Neuroscience Letters. 401: 261-5. PMID 16581181 DOI: 10.1016/J.Neulet.2006.03.031 |
0.364 |
|
| 2006 |
Furuya H, Murai H, Takasugi K, Ohyagi Y, Urano F, Kishi T, Ichinose H, Kira J. A case of late-onset Segawa syndrome (autosomal dominant dopa-responsive dystonia) with a novel mutation of the GTP-cyclohydrase I (GCH1) gene. Clinical Neurology and Neurosurgery. 108: 784-6. PMID 16289769 DOI: 10.1016/J.Clineuro.2005.10.004 |
0.313 |
|
| 2006 |
Li XG, Okada T, Kodera M, Nara Y, Takino N, Muramatsu C, Ikeguchi K, Urano F, Ichinose H, Metzger D, Chambon P, Nakano I, Ozawa K, Muramatsu S. Viral-mediated temporally controlled dopamine production in a rat model of Parkinson disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 160-6. PMID 16182609 DOI: 10.1016/J.Ymthe.2005.08.009 |
0.391 |
|
| 2005 |
Ito T, Suzuki T, Ichinose H. Nerve growth factor-induced expression of the GTP cyclohydrolase I gene via Ras/MEK pathway in PC12D cells. Journal of Neurochemistry. 95: 563-9. PMID 16190874 DOI: 10.1111/J.1471-4159.2005.03414.X |
0.312 |
|
| 2005 |
Sumi-Ichinose C, Urano F, Shimomura A, Sato T, Ikemoto K, Shiraishi H, Senda T, Ichinose H, Nomura T. Genetically rescued tetrahydrobiopterin-depleted mice survive with hyperphenylalaninemia and region-specific monoaminergic abnormalities. Journal of Neurochemistry. 95: 703-14. PMID 16135092 DOI: 10.1111/J.1471-4159.2005.03402.X |
0.386 |
|
| 2004 |
Suzuki T, Kurahashi H, Ichinose H. Ras/MEK pathway is required for NGF-induced expression of tyrosine hydroxylase gene. Biochemical and Biophysical Research Communications. 315: 389-96. PMID 14766220 DOI: 10.1016/J.Bbrc.2004.01.068 |
0.328 |
|
| 2004 |
Suzuki T, Kurita H, Ichinose H. GTP cyclohydrolase I utilizes metal-free GTP as its substrate. European Journal of Biochemistry. 271: 349-55. PMID 14717702 DOI: 10.1046/J.1432-1033.2003.03933.X |
0.306 |
|
| 2004 |
Muramatsu S, Li X, Okada T, Kodera M, Nara Y, Takino N, Ikeguchi K, Urano F, Ichinose H, Nakano I, Ozawa K. 1051. A Fail-Safe System for Gene Therapy of Parkinson's Disease; Application of Removable Expression Cassette To Prevent Overproduction of Dopamine in a Rat Model Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.996 |
0.397 |
|
| 2003 |
Shiraishi H, Kato T, Atsuta K, Sumi-Ichinose C, Ohtsuki M, Itoh M, Hishida H, Tada S, Udagawa Y, Nagatsu T, Hagino Y, Ichinose H, Nomura T. cGMP inhibits GTP cyclohydrolase I activity and biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells. Journal of Pharmacological Sciences. 93: 265-71. PMID 14646243 DOI: 10.1254/Jphs.93.265 |
0.303 |
|
| 2002 |
Ikemoto K, Suzuki T, Ichinose H, Ohye T, Nishimura A, Nishi K, Nagatsu I, Nagatsu T. Localization of sepiapterin reductase in the human brain. Brain Research. 954: 237-46. PMID 12414107 DOI: 10.1016/S0006-8993(02)03341-3 |
0.353 |
|
| 2002 |
Lee MA, Lee HS, Lee HS, Cho KG, Jin BK, Sohn S, Lee YS, Ichinose H, Kim SU. Overexpression of midbrain-specific transcription factor Nurr1 modifies susceptibility of mouse neural stem cells to neurotoxins. Neuroscience Letters. 333: 74-8. PMID 12401563 DOI: 10.1016/S0304-3940(02)00981-3 |
0.328 |
|
| 2002 |
Ikeno M, Inagaki H, Nagata K, Morita M, Ichinose H, Okazaki T. Generation of human artificial chromosomes expressing naturally controlled guanosine triphosphate cyclohydrolase I gene. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 7: 1021-32. PMID 12354096 DOI: 10.1046/J.1365-2443.2002.00580.X |
0.318 |
|
| 2002 |
Suzuki T, Yamakuni T, Hagiwara M, Ichinose H. Identification of ATF-2 as a transcriptional regulator for the tyrosine hydroxylase gene. The Journal of Biological Chemistry. 277: 40768-74. PMID 12196528 DOI: 10.1074/Jbc.M206043200 |
0.369 |
|
| 2002 |
Suzuki T, Inagaki H, Yamakuni T, Nagatsu T, Ichinose H. Enhanced expression of GTP cyclohydrolase I in V-1-overexpressing PC12D cells. Biochemical and Biophysical Research Communications. 293: 962-8. PMID 12051753 DOI: 10.1016/S0006-291X(02)00343-1 |
0.391 |
|
| 2002 |
Wang L, Muramatsu S, Lu Y, Ikeguchi K, Fujimoto K, Okada T, Mizukami H, Hanazono Y, Kume A, Urano F, Ichinose H, Nagatsu T, Nakano I, Ozawa K. Delayed delivery of AAV-GDNF prevents nigral neurodegeneration and promotes functional recovery in a rat model of Parkinson's disease. Gene Therapy. 9: 381-9. PMID 11960314 DOI: 10.1038/Sj.Gt.3301682 |
0.344 |
|
| 2002 |
Muramatsu S, Fujimoto K, Ikeguchi K, Shizuma N, Kawasaki K, Ono F, Shen Y, Wang L, Mizukami H, Kume A, Matsumura M, Nagatsu I, Urano F, Ichinose H, Nagatsu T, et al. Behavioral recovery in a primate model of Parkinson's disease by triple transduction of striatal cells with adeno-associated viral vectors expressing dopamine-synthesizing enzymes. Human Gene Therapy. 13: 345-54. PMID 11860702 DOI: 10.1089/10430340252792486 |
0.378 |
|
| 2002 |
Kawasaki H, Suemori H, Mizuseki K, Watanabe K, Urano F, Ichinose H, Haruta M, Takahashi M, Yoshikawa K, Nishikawa S, Nakatsuji N, Sasai Y. Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity. Proceedings of the National Academy of Sciences of the United States of America. 99: 1580-5. PMID 11818560 DOI: 10.1073/Pnas.032662199 |
0.325 |
|
| 2002 |
Suzuki T, Ohye T, Inagaki H, Nagatsu T, Ichinose H. Characterization of wild-type and mutants of recombinant human GTP cyclohydrolase I: relationship to etiology of dopa-responsive dystonia. Journal of Neurochemistry. 73: 2510-2516. PMID 10582612 DOI: 10.1046/J.1471-4159.1999.0732510.X |
0.326 |
|
| 2002 |
Sumi-Ichinose C, Hasegawa S, Ichinose H, Sawada H, Kobayashi K, Sakai M, Fujii T, Nomura H, Nomura T, Nagatsu I, Hagino Y, Fujita K, Nagatsu T. Analysis of the Alternative Promoters that Regulate Tissue-Specific Expression of Human Aromatic l-Amino Acid Decarboxylase Journal of Neurochemistry. 64: 514-524. PMID 7830043 DOI: 10.1046/J.1471-4159.1995.64020514.X |
0.331 |
|
| 2001 |
Ichinose H, Ohye T, Suzuki T, Inagaki H, Nagatsu T. Quantification of Tyrosine Hydroxylase mRNA Methods in Molecular Medicine. 62: 157-166. PMID 21318774 DOI: 10.1385/1-59259-142-6:157 |
0.373 |
|
| 2001 |
Ohye T, Ichinose H, Yoshizawa T, Kanazawa I, Nagatsu T. A new splicing variant for human tyrosine hydroxylase in the adrenal medulla. Neuroscience Letters. 312: 157-60. PMID 11602334 DOI: 10.1016/S0304-3940(01)02210-8 |
0.351 |
|
| 2001 |
Sumi-Ichinose C, Urano F, Kuroda R, Ohye T, Kojima M, Tazawa M, Shiraishi H, Hagino Y, Nagatsu T, Nomura T, Ichinose H. Catecholamines and serotonin are differently regulated by tetrahydrobiopterin. A study from 6-pyruvoyltetrahydropterin synthase knockout mice. Journal of Biological Chemistry. 276: 41150-41160. PMID 11517215 DOI: 10.1074/Jbc.M102237200 |
0.373 |
|
| 2001 |
Mogi M, Togari A, Kondo T, Mizuno Y, Kogure O, Kuno S, Ichinose H, Nagatsu T. Glial cell line-derived neurotrophic factor in the substantia nigra from control and parkinsonian brains Neuroscience Letters. 300: 179-181. PMID 11226640 DOI: 10.1016/S0304-3940(01)01577-4 |
0.32 |
|
| 2000 |
Nagatsu T, Mogi M, Ichinose H, Togari A. Changes in cytokines and neurotrophins in Parkinson's disease. Journal of Neural Transmission-Supplement. 277-90. PMID 11205147 DOI: 10.1007/978-3-7091-6301-6_19 |
0.318 |
|
| 2000 |
Tazawa M, Ohtsuki M, Sumi-Ichinose C, Shiraishi H, Kuroda R, Hagino Y, Nakashima S, Nozawa Y, Ichinose H, Nagatsu T, Nomura T. GTP cyclohydrolase I from Tetrahymena pyriformis: cloning of cDNA and expression. Comparative Biochemistry and Physiology B. 127: 65-73. PMID 11126753 DOI: 10.1016/S0305-0491(00)00239-X |
0.315 |
|
| 2000 |
Ichinose H, Inagaki H, Suzuki T, Ohye T, Nagatsu T. Molecular mechanisms of hereditary progressive dystonia with marked diurnal fluctuation, Segawa's disease. Brain & Development. 22: 107-110. PMID 10984669 DOI: 10.1016/S0387-7604(00)00136-4 |
0.335 |
|
| 2000 |
Maeda T, Haeno S, Oda K, Mori D, Ichinose H, Nagatsu T, Suzuki T. Studies on the genotype-phenotype relation in the hph-1 mouse mutant deficient in guanosine triphosphate (GTP) cyclohydrolase I activity Brain & Development. 22: 50-53. PMID 10984661 DOI: 10.1016/S0387-7604(00)00133-9 |
0.328 |
|
| 2000 |
Shen Y, Muramatsu SI, Ikeguchi K, Fujimoto KI, Fan DS, Ogawa M, Mizukami H, Urabe M, Kume A, Nagatsu I, Urano F, Suzuki T, Ichinose H, Nagatsu T, Monahan J, et al. Triple transduction with adeno-associated virus vectors expressing tyrosine hydroxylase, aromatic-L-amino-acid decarboxylase, and GTP cyclohydrolase I for gene therapy of Parkinson's disease. Human Gene Therapy. 11: 1509-19. PMID 10945765 DOI: 10.1089/10430340050083243 |
0.383 |
|
| 2000 |
Kaneko S, Hikida T, Watanabe D, Ichinose H, Nagatsu T, Kreitman RJ, Pastan I, Nakanishi S. Synaptic integration mediated by striatal cholinergic interneurons in basal ganglia function. Science (New York, N.Y.). 289: 633-7. PMID 10915629 DOI: 10.1126/Science.289.5479.633 |
0.323 |
|
| 1999 |
Nagatsu I, Ikemoto K, Kitahama K, Nishimura A, Ichinose H, Nagatsu T. Specific localization of the guanosine triphosphate (GTP) cyclohydrolase I-immunoreactivity in the human brain. Journal of Neural Transmission. 106: 607-617. PMID 10907721 DOI: 10.1007/S007020050183 |
0.364 |
|
| 1999 |
Ichinose H, Suzuki T, Inagaki H, Ohye T, Nagatsu T. Molecular genetics of dopa-responsive dystonia. Biological Chemistry. 380: 1355-1364. PMID 10661862 DOI: 10.1515/Bc.1999.175 |
0.407 |
|
| 1999 |
Itagaki C, Isobe T, Taoka M, Natsume T, Nomura N, Horigome T, Omata S, Ichinose H, Nagatsu T, Greene LA, Ichimura T. Stimulus-coupled interaction of tyrosine hydroxylase with 14-3-3 proteins Biochemistry. 38: 15673-15680. PMID 10569954 DOI: 10.1021/Bi9914255 |
0.322 |
|
| 1999 |
Mogi M, Togari A, Kondo T, Mizuno Y, Komure O, Kuno S, Ichinose H, Nagatsu T. Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease. Neuroscience Letters. 270: 45-48. PMID 10454142 DOI: 10.1016/S0304-3940(99)00463-2 |
0.332 |
|
| 1999 |
Inagaki H, Ohye T, Suzuki T, Segawa M, Nomura Y, Nagatsu T, Ichinose H. Decrease in GTP Cyclohydrolase I Gene Expression Caused by Inactivation of One Allele in Hereditary Progressive Dystonia with Marked Diurnal Fluctuation Biochemical and Biophysical Research Communications. 260: 747-751. PMID 10403837 DOI: 10.1006/Bbrc.1999.0976 |
0.326 |
|
| 1999 |
Mogi M, Togari A, Tanaka K, Ogawa N, Ichinose H, Nagatsu T. Increase in level of tumor necrosis factor (TNF)-α in 6-hydroxydopamine-lesioned striatum in rats without influence of systemic l-DOPA on the TNF-α induction Neuroscience Letters. 268: 101-104. PMID 10400088 DOI: 10.1016/S0304-3940(99)00388-2 |
0.303 |
|
| 1999 |
Nagatsu T, Ichinose H. Regulation of pteridine-requiring enzymes by the cofactor tetrahydrobiopterin. Molecular Neurobiology. 19: 79-96. PMID 10321973 DOI: 10.1007/Bf02741379 |
0.311 |
|
| 1999 |
Ichinose H, Ohye T, Suzuki T, Sumi-Ichinose C, Nomura T, Hagino Y, Nagatsu T. Molecular cloning of the human Nurr1 gene: characterization of the human gene and cDNAs. Gene. 230: 233-239. PMID 10216262 DOI: 10.1016/S0378-1119(99)00065-7 |
0.368 |
|
| 1999 |
Nagatsu T, Ichinose H. Molecular biology of catecholamine-related enzymes in relation to Parkinson's disease. Cellular and Molecular Neurobiology. 19: 57-66. PMID 10079965 DOI: 10.1023/A:1006912523846 |
0.364 |
|
| 1999 |
Fan DS, Ogawa M, Fujimoto KI, Ikeguchi K, Ogasawara Y, Urabe M, Nishizawa M, Nakano I, Yoshida M, Nagatsu I, Ichinose H, Nagatsu T, Kurtzman GJ, Ozawa K. Behavioral recovery in 6-hydroxydopamine-lesioned rats by cotransduction of striatum with tyrosine hydroxylase and aromatic L-amino acid decarboxylase genes using two separate adeno-associated virus vectors. Human Gene Therapy. 9: 2527-35. PMID 9853519 DOI: 10.1089/Hum.1998.9.17-2527 |
0.389 |
|
| 1998 |
Nomura T, Tazawa M, Ohtsuki M, Sumi-Ichinose C, Hagino Y, Ota A, Nakashima A, Mori K, Sugimoto T, Ueno O, Nozawa Y, Ichinose H, Nagatsu T. Enzymes related to catecholamine biosynthesis in Tetrahymena pyriformis. Presence of GTP cyclohydrolase I. Comparative Biochemistry and Physiology B. 120: 753-760. PMID 9854821 DOI: 10.1016/S0305-0491(98)10075-5 |
0.36 |
|
| 1998 |
Ohye T, Hori T, Katoh S, Nagatsu T, Ichinose H. Genomic Organization and Chromosomal Localization of the Human Sepiapterin Reductase Gene Biochemical and Biophysical Research Communications. 251: 597-602. PMID 9792819 DOI: 10.1006/Bbrc.1998.9503 |
0.33 |
|
| 1998 |
Fan D, Ogawa M, Ikeguchi K, Fujimoto K, Urabe M, Kume A, Nishizawa M, Matsushita N, Kiuchi K, Ichinose H, Nagatsu T, Kurtzman GJ, Nakano I, Ozawa K. Prevention of dopaminergic neuron death by adeno-associated virus vector-mediated GDNF gene transfer in rat mesencephalic cells in vitro. Neuroscience Letters. 248: 61-64. PMID 9665664 DOI: 10.1016/S0304-3940(98)00313-9 |
0.308 |
|
| 1997 |
Nagatsu T, Ichinose H. Genetic basis of dominant dystonia. Advances in Pharmacology. 42: 44-47. PMID 9327842 DOI: 10.1016/S1054-3589(08)60691-2 |
0.4 |
|
| 1997 |
Ichinose H, Nagatsu T. Molecular Genetics of Hereditary Dystonia—Mutations in the GTP Cyclohydrolase I Gene Brain Research Bulletin. 43: 35-38. PMID 9205791 DOI: 10.1016/S0361-9230(96)00353-X |
0.376 |
|
| 1997 |
Ichinose H, Ohye T, Nagatsu T. 804 Gene structures of three tetrahydrobiopterin-synthesizing enzymes and the regulatory mechanisms of their expression 1 Neuroscience Research. 28. DOI: 10.1016/S0168-0102(97)90266-2 |
0.301 |
|
| 1997 |
Nagatsu T, Ichinose H. GTP cydohydrolase I gene, dystonia, juvenile parkinsonism, and Parkinson’s disease Journal of Neural Transmission-Supplement. 49: 203-209. DOI: 10.1007/978-3-7091-6844-8_21 |
0.389 |
|
| 1995 |
Nagatsu I, Ichinose H, Sakai M, Titani K, Suzuki M, Nagatsu T. Immunocytochemical localization of GTP cyclohydrolase I in the brain, adrenal gland, and liver of mice Journal of Neural Transmission. 102: 175-188. PMID 8788067 DOI: 10.1007/Bf01281153 |
0.359 |
|
| 1995 |
Ota A, Ichinose H, Nagatsu T. Mouse sepiapterin reductase: an enzyme involved in the final step of tetrahydrobiopterin biosynthesis. Primary structure deduced from the cDNA sequence Biochimica Et Biophysica Acta. 1260: 320-322. PMID 7873607 DOI: 10.1016/0167-4781(94)00225-R |
0.318 |
|
| 1995 |
Ichinose H, Ohye T, Matsuda Y, Hori TA, Blau N, Burlina A, Rouse B, Matalon R, Fujita K, Nagatsu T. Characterization of mouse and human GTP cyclohydrolase I genes. Mutations in patients with GTP cyclohydrolase I deficiency. Journal of Biological Chemistry. 270: 10062-10071. PMID 7730309 DOI: 10.1074/Jbc.270.17.10062 |
0.359 |
|
| 1995 |
Ichinose H, Ohye T, Yokochi M, Fujit K, Nagatsu T. GTP cyclohydrolase I activity in mononuclear blood cells in juvenile parkinsonism. Neuroscience Letters. 190: 140-142. PMID 7644124 DOI: 10.1016/0304-3940(95)11511-T |
0.355 |
|
| 1995 |
Ohye T, Ichinose H, Ogawa M, Yoshida M, Nagatsu T. Alterations in multiple tyrosine hydroxylase mRNAs in the substantia nigra, locus coeruleus and adrenal gland of MPTP-treated parkinsonian monkeys. Neurodegeneration. 4: 81-85. PMID 7600187 DOI: 10.1006/Neur.1995.0009 |
0.364 |
|
| 1994 |
Ota A, Ichinose H, Kobayashi K, Morita S, Sawada H, Mizuguchi T, Nagatsu T. Nicotine-induced regulation of tyrosine hydroxylase activity in adrenal gland of transgenic mouse carrying human tyrosine hydroxylase gene Neuroscience Letters. 166: 55-58. PMID 7910680 DOI: 10.1016/0304-3940(94)90839-7 |
0.349 |
|
| 1994 |
Ichinose H, Ohye T, Takahashi Ei, Seki N, Hori Ta, Segawa M, Nomura Y, Endo K, Tanaka H, Tsuji S, Fujita K, Nagatsu T. Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene Nature Genetics. 8: 236-242. PMID 7874165 DOI: 10.1038/Ng1194-236 |
0.318 |
|
| 1994 |
Nasrin S, Ichinose H, Hidaka H, Nagatsu T. Recombinant human tyrosine hydroxylase types 1-4 show regulatory kinetic properties for the natural (6R)-tetrahydrobiopterin cofactor. Journal of Biochemistry. 116: 393-398. PMID 7822259 DOI: 10.1093/Oxfordjournals.Jbchem.A124537 |
0.322 |
|
| 1993 |
Nomura T, Ichinose H, Sumi-Ichinose C, Nomura H, Hagino Y, Fujita K, Nagatsu T. Cloning and Sequencing of cDNA Encoding Mouse GTP Cyclohydrolase 1 Biochemical and Biophysical Research Communications. 191: 523-527. PMID 8461009 DOI: 10.1006/Bbrc.1993.1249 |
0.304 |
|
| 1993 |
Ichinose H, Ohye T, Fujita K, Yoshida M, Ueda S, Nagatsu T. Increased Heterogeneity of Tyrosine Hydroxylase in Humans Biochemical and Biophysical Research Communications. 195: 158-165. PMID 7689834 DOI: 10.1006/Bbrc.1993.2024 |
0.325 |
|
| 1992 |
Nasrin S, Ichinose H, Nagatsu T. Comparison of characteristics of bovine aromatic L-amino acid decarboxylase with human enzyme. Biochimica Et Biophysica Acta. 1118: 318-322. PMID 1737055 DOI: 10.1016/0167-4838(92)90291-K |
0.317 |
|
| 1992 |
Sumi-Ichinose C, Ichinose H, Takahashi E, Hori T, Nagatsu T. Molecular cloning of genomic DNA and chromosomal assignment of the gene for human aromatic L-amino acid decarboxylase, the enzyme for catecholamine and serotonin biosynthesis. Biochemistry. 31: 2229-2238. PMID 1540578 DOI: 10.1021/Bi00123A004 |
0.342 |
|
| 1992 |
Ichinose H, Sumi-Ichinose C, Ohye T, Hagino Y, Fujita K, Nagatsu T. Tissue-specific alternative splicing of the first exon generates two types of mRNAs in human aromatic L-amino acid decarboxylase. Biochemistry. 31: 11546-11550. PMID 1445888 DOI: 10.1021/Bi00161A036 |
0.313 |
|
| 1991 |
Ichinose H, Katoh S, Sueoka T, Titani K, Fujita K, Nagatsu T. Cloning and Sequencing of cDNA Encoding Human Sepiapterin Reductase Biochemical and Biophysical Research Communications. 179: 183-189. PMID 1883349 DOI: 10.1016/0006-291X(91)91352-D |
0.314 |
|
| 1989 |
Ichinose H, Kurosawa Y, Titani K, Fujita K, Nagatsu T. Isolation and characterization of a cDNA clone encoding human aromatic L-amino acid decarboxylase. Biochemical and Biophysical Research Communications. 164: 1024-30. PMID 2590185 DOI: 10.1016/0006-291X(89)91772-5 |
0.312 |
|
| 1989 |
Naoi M, Takahashi T, Ichinose H, Wakabayashi K, Sugimura T, Nagatsu T. Uptake of heterocyclic amines, Trp-P-1 and Trp-P-2, into clonal rat pheochromocytoma PC12h cells by dopamine uptake system. Neuroscience Letters. 99: 317-322. PMID 2524682 DOI: 10.1016/0304-3940(89)90466-7 |
0.309 |
|
| 1988 |
Naoi M, Takahashi T, Ichinose H, Nagatsu T. Inhibition of aromatic L-aminoacid decarboxylase in clonal pheochromocytoma PC12h cells by N-methyl-4-phenylpyridinium ion (MPP+) Biochemical and Biophysical Research Communications. 152: 15-21. PMID 3258744 DOI: 10.1016/S0006-291X(88)80673-9 |
0.306 |
|
| 1988 |
Naoi M, Takahashi T, Ichinose H, Wakabayashi K, Sugimura T, Nagatsu T. Reduction of enzyme activity of tyrosine hydroxylase and aromatic L-aminoacid decarboxylase in clonal pheochromocytoma PC12h cells by carcinogenic heterocyclic amines. Biochemical and Biophysical Research Communications. 157: 494-499. PMID 2904812 DOI: 10.1016/S0006-291X(88)80276-6 |
0.341 |
|
| 1988 |
Kobayashi K, Kaneda N, Ichinose H, Kishi F, Nakazawa A, Kurosawa Y, Fujita K, Nagatsu T. Structure of the human tyrosine hydroxylase gene: alternative splicing from a single gene accounts for generation of four mRNA types. Journal of Biochemistry. 103: 907-12. PMID 2902075 DOI: 10.1093/Oxfordjournals.Jbchem.A122386 |
0.349 |
|
| 1987 |
Ichinose H, Togari A, Suzuki H, Kumagai H, Nagatsu T. Increase of Catecholamines in Mouse Brain by Systemic Administration of γ-Glutamyl L-3,4-Dihydroxyphenylalanine Journal of Neurochemistry. 49: 928-932. PMID 3112308 DOI: 10.1111/J.1471-4159.1987.Tb00982.X |
0.347 |
|
| 1987 |
Kaneda N, Kobayashi K, Ichinose H, Kishi F, Nakazawa A, Kurosawa Y, Fujita K, Nagatsu T. Isolation of a novel cDNA clone for human tyrosine hydroxylase: alternative RNA splicing produces four kinds of mRNA from a single gene. Biochemical and Biophysical Research Communications. 146: 971-5. PMID 2887169 DOI: 10.1016/0006-291X(87)90742-X |
0.325 |
|
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