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Year Citation  Score
2019 Yang T, Yang K, Chen Y, Fan K. Characterization of a Bi-directional Promoter OtrRp Involved in Oxytetracycline Biosynthesis. Current Microbiology. PMID 31410507 DOI: 10.1007/S00284-019-01753-1  0.38
2019 Wang J, Wang W, Wang H, Yuan F, Xu Z, Yang K, Li Z, Chen Y, Fan K. Improvement of stress tolerance and riboflavin production of Bacillus subtilis by introduction of heat shock proteins from thermophilic bacillus strains. Applied Microbiology and Biotechnology. PMID 30968162 DOI: 10.1007/S00253-019-09788-X  0.313
2017 Liu C, Zhang B, Liu YM, Yang K, Liu SJ. New intracellular shikimic acid biosensor for monitoring shikimate synthesis in Corynebacterium glutamicum. Acs Synthetic Biology. PMID 29087704 DOI: 10.1021/Acssynbio.7B00339  0.355
2017 Li S, Wang J, Xiang W, Yang K, Li Z, Wang W. An autoregulated fine-tuning strategy for titer improvement of secondary metabolites using native promoters in Streptomyces. Acs Synthetic Biology. PMID 29087698 DOI: 10.1021/Acssynbio.7B00318  0.347
2017 Yin S, Wang X, Shi M, Yuan F, Wang H, Jia X, Yuan F, Sun J, Liu T, Yang K, Zhang Y, Fan K, Li Z. Improvement of oxytetracycline production mediated via cooperation of resistance genes in Streptomyces rimosus. Science China. Life Sciences. PMID 28755296 DOI: 10.1007/S11427-017-9121-4  0.356
2017 Li X, Wang J, Shi M, Wang W, Corre C, Yang K. Evidence for the formation of ScbR/ScbR2 heterodimers and identification of one of the regulatory targets in Streptomyces coelicolor. Applied Microbiology and Biotechnology. PMID 28439624 DOI: 10.1007/S00253-017-8275-8  0.333
2017 Li L, Pan G, Zhu X, Fan K, Gao W, Ai G, Ren J, Shi M, Olano C, Salas JA, Yang K. Engineered jadomycin analogues with altered sugar moieties revealing JadS as a substrate flexible O-glycosyltransferase. Applied Microbiology and Biotechnology. PMID 28429060 DOI: 10.1007/S00253-017-8256-Y  0.633
2017 Pan G, Gao X, Fan K, Liu J, Meng B, Gao J, Wang B, Zhang C, Han H, Ai G, Chen Y, Wu D, Liu ZJ, Yang K. Structure and Function of a C-C Bond Cleaving Oxygenase in Atypical Angucycline Biosynthesis. Acs Chemical Biology. 12: 142-152. PMID 28103689 DOI: 10.1021/Acschembio.6B00621  0.653
2016 Fan K, Lin B, Tao Y, Yang K. Engineering deacetoxycephalosporin C synthase as a catalyst for the bioconversion of penicillins. Journal of Industrial Microbiology & Biotechnology. PMID 27826726 DOI: 10.1007/S10295-016-1857-0  0.323
2016 Yin S, Li Z, Wang X, Wang H, Jia X, Ai G, Bai Z, Shi M, Yuan F, Liu T, Wang W, Yang K. Heterologous expression of oxytetracycline biosynthetic gene cluster in Streptomyces venezuelae WVR2006 to improve production level and to alter fermentation process. Applied Microbiology and Biotechnology. PMID 27709288 DOI: 10.1007/S00253-016-7873-1  0.374
2016 Sidda JD, Poon V, Song L, Wang W, Yang K, Corre C. Overproduction and identification of butyrolactones SCB1-8 in the antibiotic production superhost Streptomyces M1152. Organic & Biomolecular Chemistry. PMID 27180870 DOI: 10.1039/C6Ob00840B  0.318
2016 Wang W, Yang T, Li Y, Li S, Yin S, Styles K, Corre C, Yang K. Development of a synthetic oxytetracycline-inducible expression system for streptomycetes using de novo characterized genetic parts. Acs Synthetic Biology. PMID 27100123 DOI: 10.1021/Acssynbio.6B00087  0.328
2015 Li S, Wang W, Li X, Fan K, Yang K. Genome-wide identification and characterization of reference genes with different transcript abundances for Streptomyces coelicolor. Scientific Reports. 5: 15840. PMID 26527303 DOI: 10.1038/Srep15840  0.357
2015 Li S, Wang J, Li X, Yin S, Wang W, Yang K. Genome-wide identification and evaluation of constitutive promoters in streptomycetes. Microbial Cell Factories. 14: 172. PMID 26515616 DOI: 10.1186/S12934-015-0351-0  0.376
2015 Wang W, Li X, Li Y, Li S, Fan K, Yang K. A genetic biosensor for identification of transcriptional repressors of target promoters. Scientific Reports. 5: 15887. PMID 26510468 DOI: 10.1038/Srep15887  0.323
2015 Wang B, Guo F, Ren J, Ai G, Aigle B, Fan K, Yang K. Identification of Alp1U and Lom6 as epoxy hydrolases and implications for kinamycin and lomaiviticin biosynthesis. Nature Communications. 6: 7674. PMID 26134788 DOI: 10.1038/Ncomms8674  0.424
2015 Wang B, Ren J, Li L, Guo F, Pan G, Ai G, Aigle B, Fan K, Yang K. Kinamycin biosynthesis employs a conserved pair of oxidases for B-ring contraction. Chemical Communications (Cambridge, England). 51: 8845-8. PMID 25920893 DOI: 10.1039/C5Cc01986A  0.652
2015 Yin S, Wang W, Wang X, Zhu Y, Jia X, Li S, Yuan F, Zhang Y, Yang K. Identification of a cluster-situated activator of oxytetracycline biosynthesis and manipulation of its expression for improved oxytetracycline production in Streptomyces rimosus. Microbial Cell Factories. 14: 46. PMID 25886456 DOI: 10.1186/S12934-015-0231-7  0.401
2015 Guo F, Xiang S, Li L, Wang B, Rajasärkkä J, Gröndahl-Yli-Hannuksela K, Ai G, Metsä-Ketelä M, Yang K. Targeted activation of silent natural product biosynthesis pathways by reporter-guided mutant selection. Metabolic Engineering. 28: 134-42. PMID 25554073 DOI: 10.1016/J.Ymben.2014.12.006  0.428
2014 Wang W, Ji J, Li X, Wang J, Li S, Pan G, Fan K, Yang K. Angucyclines as signals modulate the behaviors of Streptomyces coelicolor. Proceedings of the National Academy of Sciences of the United States of America. 111: 5688-93. PMID 24706927 DOI: 10.1073/Pnas.1324253111  0.635
2013 Zhang Y, Pan G, Zou Z, Fan K, Yang K, Tan H. JadR*-mediated feed-forward regulation of cofactor supply in jadomycin biosynthesis. Molecular Microbiology. 90: 884-97. PMID 24112541 DOI: 10.1111/Mmi.12406  0.66
2013 Guo D, Zhao Y, Yang K. Coordination of glycerol utilization and clavulanic acid biosynthesis to improve clavulanic acid production in Streptomyces clavuligerus. Science China. Life Sciences. 56: 591-600. PMID 23832248 DOI: 10.1007/S11427-013-4507-Z  0.727
2013 Kallio P, Patrikainen P, Belogurov GA, Mäntsälä P, Yang K, Niemi J, Metsä-Ketelä M. Tracing the evolution of angucyclinone monooxygenases: structural determinants for C-12b hydroxylation and substrate inhibition in PgaE. Biochemistry. 52: 4507-16. PMID 23731237 DOI: 10.1021/Bi400381S  0.364
2013 Wang W, Li X, Wang J, Xiang S, Feng X, Yang K. An engineered strong promoter for streptomycetes. Applied and Environmental Microbiology. 79: 4484-92. PMID 23686264 DOI: 10.1128/Aem.00985-13  0.327
2013 Zhao Y, Xiang S, Dai X, Yang K. A simplified diphenylamine colorimetric method for growth quantification. Applied Microbiology and Biotechnology. 97: 5069-77. PMID 23604560 DOI: 10.1007/S00253-013-4893-Y  0.698
2012 Fan K, Pan G, Peng X, Zheng J, Gao W, Wang J, Wang W, Li Y, Yang K. Identification of JadG as the B ring opening oxygenase catalyzing the oxidative C-C bond cleavage reaction in jadomycin biosynthesis. Chemistry & Biology. 19: 1381-90. PMID 23177193 DOI: 10.1016/J.Chembiol.2012.09.009  0.651
2012 Ji J, Fan K, Tian X, Zhang X, Zhang Y, Yang K. Iterative combinatorial mutagenesis as an effective strategy for generation of deacetoxycephalosporin C synthase with improved activity toward penicillin G. Applied and Environmental Microbiology. 78: 7809-12. PMID 22923414 DOI: 10.1128/Aem.02122-12  0.304
2012 Patrikainen P, Kallio P, Fan K, Klika KD, Shaaban KA, Mäntsälä P, Rohr J, Yang K, Niemi J, Metsä-Ketelä M. Tailoring enzymes involved in the biosynthesis of angucyclines contain latent context-dependent catalytic activities. Chemistry & Biology. 19: 647-55. PMID 22633416 DOI: 10.1016/J.Chembiol.2012.04.010  0.357
2012 Yu T, Xu X, Peng Y, Luo Y, Yang K. Cell wall proteome of Clostridium thermocellum and detection of glycoproteins. Microbiological Research. 167: 364-71. PMID 22494898 DOI: 10.1016/J.Micres.2012.02.006  0.324
2012 Yin H, Xiang S, Zheng J, Fan K, Yu T, Yang X, Peng Y, Wang H, Feng D, Luo Y, Bai H, Yang K. Induction of holomycin production and complex metabolic changes by the argR mutation in Streptomyces clavuligerus NP1. Applied and Environmental Microbiology. 78: 3431-41. PMID 22344669 DOI: 10.1128/Aem.07699-11  0.376
2012 Ji J, Tian X, Fan K, Yang K. New strategy of site-directed mutagenesis identifies new sites to improve Streptomyces clavuligerus deacetoxycephalosporin C synthase activity toward penicillin G. Applied Microbiology and Biotechnology. 93: 2395-401. PMID 21909691 DOI: 10.1007/S00253-011-3566-Y  0.314
2011 Wang J, Wang W, Wang L, Zhang G, Fan K, Tan H, Yang K. A novel role of 'pseudo'γ-butyrolactone receptors in controlling γ-butyrolactone biosynthesis in Streptomyces. Molecular Microbiology. 82: 236-50. PMID 21883525 DOI: 10.1111/J.1365-2958.2011.07811.X  0.339
2011 Ouyang Y, Wu H, Xie L, Wang G, Dai S, Chen M, Yang K, Li X. A method to type the potential angucycline producers in actinomycetes isolated from marine sponges. Antonie Van Leeuwenhoek. 99: 807-15. PMID 21287404 DOI: 10.1007/S10482-011-9554-5  0.368
2011 Peng Y, Luo Y, Yu T, Xu X, Fan K, Zhao Y, Yang K. A blue native-PAGE analysis of membrane protein complexes in Clostridium thermocellum. Bmc Microbiology. 11: 22. PMID 21269440 DOI: 10.1186/1471-2180-11-22  0.702
2011 Wu X, Tian X, Ji J, Wu W, Fan K, Yang K. Saturation mutagenesis of Acremonium chrysogenum deacetoxy/deacetylcephalosporin C synthase R308 site confirms its role in controlling substrate specificity Biotechnology Letters. 33: 805-812. PMID 21190060 DOI: 10.1007/S10529-010-0504-5  0.342
2010 Xu G, Wang J, Wang L, Tian X, Yang H, Fan K, Yang K, Tan H. "Pseudo" gamma-butyrolactone receptors respond to antibiotic signals to coordinate antibiotic biosynthesis. The Journal of Biological Chemistry. 285: 27440-8. PMID 20562102 DOI: 10.1074/Jbc.M110.143081  0.31
2009 Xiang SH, Li J, Yin H, Zheng JT, Yang X, Wang HB, Luo JL, Bai H, Yang KQ. Application of a double-reporter-guided mutant selection method to improve clavulanic acid production in Streptomyces clavuligerus. Metabolic Engineering. 11: 310-8. PMID 19584003 DOI: 10.1016/J.Ymben.2009.06.003  0.331
2009 Wang L, Tian X, Wang J, Yang H, Fan K, Xu G, Yang K, Tan H. Autoregulation of antibiotic biosynthesis by binding of the end product to an atypical response regulator. Proceedings of the National Academy of Sciences of the United States of America. 106: 8617-22. PMID 19423672 DOI: 10.1073/Pnas.0900592106  0.393
2008 Xu X, Wang Z, Fan K, Wang S, Jia C, Han H, Ramalingam E, Yang K. Localization of the ActIII actinorhodin polyketide ketoreductase to the cell wall Fems Microbiology Letters. 287: 15-21. PMID 18691223 DOI: 10.1111/J.1574-6968.2008.01289.X  0.317
2008 Wang S, Fan K, Yang X, Lin Z, Xu X, Yang K. CabC, an EF-Hand Calcium-Binding Protein, Is Involved in Ca2+-Mediated Regulation of Spore Germination and Aerial Hypha Formation in Streptomyces coelicolor Journal of Bacteriology. 190: 4061-4068. PMID 18375559 DOI: 10.1128/Jb.01954-07  0.311
2007 Zheng J, Wang S, Yang K. Engineering a regulatory region of jadomycin gene cluster to improve jadomycin B production in Streptomyces venezuelae Applied Microbiology and Biotechnology. 76: 883-888. PMID 17653711 DOI: 10.1007/S00253-007-1064-Z  0.407
2007 He Y, Fan K, Jia C, Wang Z, Pan W, Huang L, Yang K, Dong Z. Characterization of a hyperthermostable Fe-superoxide dismutase from hot spring. Applied Microbiology and Biotechnology. 75: 367-376. PMID 17262208 DOI: 10.1007/S00253-006-0834-3  0.338
2005 Wu X, Fan K, Wang Q, Yang K. C-terminus mutations of Acremonium chrysogenum deacetoxy/deacetylcephalosporin C synthase with improved activity toward penicillin analogs Fems Microbiology Letters. 246: 103-110. PMID 15869968 DOI: 10.1016/J.Femsle.2005.03.043  0.316
2005 Chen YH, Wang CC, Greenwell L, Rix U, Hoffmeister D, Vining LC, Rohr J, Yang KQ. Functional analyses of oxygenases in jadomycin biosynthesis and identification of JadH as a bifunctional oxygenase/dehydrase Journal of Biological Chemistry. 280: 22508-22514. PMID 15817470 DOI: 10.1074/Jbc.M414229200  0.682
2005 Rix U, Wang C, Chen Y, Lipata FM, Rix LLR, Greenwell LM, Vining LC, Yang K, Rohr J. The oxidative ring cleavage in jadomycin biosynthesis: A multistep oxygenation cascade in a biosynthetic black box Chembiochem. 6: 838-845. PMID 15776503 DOI: 10.1002/Cbic.200400395  0.705
2004 Rix U, Zheng J, Remsing Rix LL, Greenwell L, Yang K, Rohr J. The dynamic structure of jadomycin B and the amino acid incorporation step of its biosynthesis. Journal of the American Chemical Society. 126: 4496-7. PMID 15070349 DOI: 10.1021/Ja031724O  0.346
2001 Yang K, Han L, He J, Wang L, Vining LC. A repressor-response regulator gene pair controlling jadomycin B production in Streptomyces venezuelae ISP5230 Gene. 279: 165-173. PMID 11733141 DOI: 10.1016/S0378-1119(01)00723-5  0.76
2000 Han L, Yang K, Kulowski K, Wendt-Pienkowski E, Hutchinson CR, Vining LC. An acyl-coenzyme A carboxylase encoding gene associated with jadomycin biosynthesis in Streptomyces venezuelae ISP5230 Microbiology. 146: 903-910. PMID 10784049 DOI: 10.1099/00221287-146-4-903  0.693
1999 Kulowski K, Wendt-Pienkowski E, Han L, Yang K, Vining LC, Richard Hutchinson C. Functional characterization of the jadI gene as a cyclase forming angucyclinones Journal of the American Chemical Society. 121: 1786-1794. DOI: 10.1021/ja982707f  0.615
1997 Bateman KP, Thibault P, Yang K, White RL, Vining LC. Probing the substrate specificity of an enzyme catalyzing inactivation of streptogramin B antibiotics using LC-MS and LC-MS/MS. Journal of Mass Spectrometry : Jms. 32: 1057-63. PMID 9358629 DOI: 10.1002/(Sici)1096-9888(199711)32:10<1057::Aid-Jms558>3.0.Co;2-D  0.63
1996 Facey SJ, Groß F, Vining LC, Yang K, Van Pée KH. Cloning, sequencing and disruption of a bromoperoxidase-catalase gene in Streptomyces venezuelae: Evidence that it is not required for chlorination in chloramphenicol biosynthesis Microbiology. 142: 657-665. PMID 8868441 DOI: 10.1099/13500872-142-3-657  0.666
1996 Yang K, Han L, Ayer SW, Vining LC. Accumulation of the angucycline antibiotic rabelomycin after disruption of an oxygenase gene in the jadomycin B biosynthetic gene cluster of Streptomyces venezuelae Microbiology. 142: 123-132. PMID 8581159 DOI: 10.1099/13500872-142-1-123  0.691
1996 Bateman KP, Yang K, Thibault P, White RL, Vining LC. Inactivation of etamycin by a novel elimination mechanism in Streptomyces lividans Journal of the American Chemical Society. 118: 5335-5338. DOI: 10.1021/Ja9539103  0.644
1995 Mosher RH, Camp DJ, Yang K, Brown MP, Shaw WV, Vining LC. Inactivation of chloramphenicol by O-phosphorylation. A novel resistance mechanism in Streptomyces venezuelae ISP5230, a chloramphenicol producer Journal of Biological Chemistry. 270: 27000-27006. PMID 7592948 DOI: 10.1074/Jbc.270.45.27000  0.653
1994 Han L, Yang K, Ramalingam E, Mosher RH, Vining LC. Cloning and characterization of polyketide synthase genes for jadomycin B biosynthesis in Streptomyces venezuelae ISP5230 Microbiology. 140: 3379-3389. PMID 7881555 DOI: 10.1099/13500872-140-12-3379  0.679
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