Year |
Citation |
Score |
2019 |
Yang T, Yang K, Chen Y, Fan K. Characterization of a Bi-directional Promoter OtrRp Involved in Oxytetracycline Biosynthesis. Current Microbiology. PMID 31410507 DOI: 10.1007/S00284-019-01753-1 |
0.38 |
|
2019 |
Wang J, Wang W, Wang H, Yuan F, Xu Z, Yang K, Li Z, Chen Y, Fan K. Improvement of stress tolerance and riboflavin production of Bacillus subtilis by introduction of heat shock proteins from thermophilic bacillus strains. Applied Microbiology and Biotechnology. PMID 30968162 DOI: 10.1007/S00253-019-09788-X |
0.313 |
|
2017 |
Liu C, Zhang B, Liu YM, Yang K, Liu SJ. New intracellular shikimic acid biosensor for monitoring shikimate synthesis in Corynebacterium glutamicum. Acs Synthetic Biology. PMID 29087704 DOI: 10.1021/Acssynbio.7B00339 |
0.355 |
|
2017 |
Li S, Wang J, Xiang W, Yang K, Li Z, Wang W. An autoregulated fine-tuning strategy for titer improvement of secondary metabolites using native promoters in Streptomyces. Acs Synthetic Biology. PMID 29087698 DOI: 10.1021/Acssynbio.7B00318 |
0.347 |
|
2017 |
Yin S, Wang X, Shi M, Yuan F, Wang H, Jia X, Yuan F, Sun J, Liu T, Yang K, Zhang Y, Fan K, Li Z. Improvement of oxytetracycline production mediated via cooperation of resistance genes in Streptomyces rimosus. Science China. Life Sciences. PMID 28755296 DOI: 10.1007/S11427-017-9121-4 |
0.356 |
|
2017 |
Li X, Wang J, Shi M, Wang W, Corre C, Yang K. Evidence for the formation of ScbR/ScbR2 heterodimers and identification of one of the regulatory targets in Streptomyces coelicolor. Applied Microbiology and Biotechnology. PMID 28439624 DOI: 10.1007/S00253-017-8275-8 |
0.333 |
|
2017 |
Li L, Pan G, Zhu X, Fan K, Gao W, Ai G, Ren J, Shi M, Olano C, Salas JA, Yang K. Engineered jadomycin analogues with altered sugar moieties revealing JadS as a substrate flexible O-glycosyltransferase. Applied Microbiology and Biotechnology. PMID 28429060 DOI: 10.1007/S00253-017-8256-Y |
0.633 |
|
2017 |
Pan G, Gao X, Fan K, Liu J, Meng B, Gao J, Wang B, Zhang C, Han H, Ai G, Chen Y, Wu D, Liu ZJ, Yang K. Structure and Function of a C-C Bond Cleaving Oxygenase in Atypical Angucycline Biosynthesis. Acs Chemical Biology. 12: 142-152. PMID 28103689 DOI: 10.1021/Acschembio.6B00621 |
0.653 |
|
2016 |
Fan K, Lin B, Tao Y, Yang K. Engineering deacetoxycephalosporin C synthase as a catalyst for the bioconversion of penicillins. Journal of Industrial Microbiology & Biotechnology. PMID 27826726 DOI: 10.1007/S10295-016-1857-0 |
0.323 |
|
2016 |
Yin S, Li Z, Wang X, Wang H, Jia X, Ai G, Bai Z, Shi M, Yuan F, Liu T, Wang W, Yang K. Heterologous expression of oxytetracycline biosynthetic gene cluster in Streptomyces venezuelae WVR2006 to improve production level and to alter fermentation process. Applied Microbiology and Biotechnology. PMID 27709288 DOI: 10.1007/S00253-016-7873-1 |
0.374 |
|
2016 |
Sidda JD, Poon V, Song L, Wang W, Yang K, Corre C. Overproduction and identification of butyrolactones SCB1-8 in the antibiotic production superhost Streptomyces M1152. Organic & Biomolecular Chemistry. PMID 27180870 DOI: 10.1039/C6Ob00840B |
0.318 |
|
2016 |
Wang W, Yang T, Li Y, Li S, Yin S, Styles K, Corre C, Yang K. Development of a synthetic oxytetracycline-inducible expression system for streptomycetes using de novo characterized genetic parts. Acs Synthetic Biology. PMID 27100123 DOI: 10.1021/Acssynbio.6B00087 |
0.328 |
|
2015 |
Li S, Wang W, Li X, Fan K, Yang K. Genome-wide identification and characterization of reference genes with different transcript abundances for Streptomyces coelicolor. Scientific Reports. 5: 15840. PMID 26527303 DOI: 10.1038/Srep15840 |
0.357 |
|
2015 |
Li S, Wang J, Li X, Yin S, Wang W, Yang K. Genome-wide identification and evaluation of constitutive promoters in streptomycetes. Microbial Cell Factories. 14: 172. PMID 26515616 DOI: 10.1186/S12934-015-0351-0 |
0.376 |
|
2015 |
Wang W, Li X, Li Y, Li S, Fan K, Yang K. A genetic biosensor for identification of transcriptional repressors of target promoters. Scientific Reports. 5: 15887. PMID 26510468 DOI: 10.1038/Srep15887 |
0.323 |
|
2015 |
Wang B, Guo F, Ren J, Ai G, Aigle B, Fan K, Yang K. Identification of Alp1U and Lom6 as epoxy hydrolases and implications for kinamycin and lomaiviticin biosynthesis. Nature Communications. 6: 7674. PMID 26134788 DOI: 10.1038/Ncomms8674 |
0.424 |
|
2015 |
Wang B, Ren J, Li L, Guo F, Pan G, Ai G, Aigle B, Fan K, Yang K. Kinamycin biosynthesis employs a conserved pair of oxidases for B-ring contraction. Chemical Communications (Cambridge, England). 51: 8845-8. PMID 25920893 DOI: 10.1039/C5Cc01986A |
0.652 |
|
2015 |
Yin S, Wang W, Wang X, Zhu Y, Jia X, Li S, Yuan F, Zhang Y, Yang K. Identification of a cluster-situated activator of oxytetracycline biosynthesis and manipulation of its expression for improved oxytetracycline production in Streptomyces rimosus. Microbial Cell Factories. 14: 46. PMID 25886456 DOI: 10.1186/S12934-015-0231-7 |
0.401 |
|
2015 |
Guo F, Xiang S, Li L, Wang B, Rajasärkkä J, Gröndahl-Yli-Hannuksela K, Ai G, Metsä-Ketelä M, Yang K. Targeted activation of silent natural product biosynthesis pathways by reporter-guided mutant selection. Metabolic Engineering. 28: 134-42. PMID 25554073 DOI: 10.1016/J.Ymben.2014.12.006 |
0.428 |
|
2014 |
Wang W, Ji J, Li X, Wang J, Li S, Pan G, Fan K, Yang K. Angucyclines as signals modulate the behaviors of Streptomyces coelicolor. Proceedings of the National Academy of Sciences of the United States of America. 111: 5688-93. PMID 24706927 DOI: 10.1073/Pnas.1324253111 |
0.635 |
|
2013 |
Zhang Y, Pan G, Zou Z, Fan K, Yang K, Tan H. JadR*-mediated feed-forward regulation of cofactor supply in jadomycin biosynthesis. Molecular Microbiology. 90: 884-97. PMID 24112541 DOI: 10.1111/Mmi.12406 |
0.66 |
|
2013 |
Guo D, Zhao Y, Yang K. Coordination of glycerol utilization and clavulanic acid biosynthesis to improve clavulanic acid production in Streptomyces clavuligerus. Science China. Life Sciences. 56: 591-600. PMID 23832248 DOI: 10.1007/S11427-013-4507-Z |
0.727 |
|
2013 |
Kallio P, Patrikainen P, Belogurov GA, Mäntsälä P, Yang K, Niemi J, Metsä-Ketelä M. Tracing the evolution of angucyclinone monooxygenases: structural determinants for C-12b hydroxylation and substrate inhibition in PgaE. Biochemistry. 52: 4507-16. PMID 23731237 DOI: 10.1021/Bi400381S |
0.364 |
|
2013 |
Wang W, Li X, Wang J, Xiang S, Feng X, Yang K. An engineered strong promoter for streptomycetes. Applied and Environmental Microbiology. 79: 4484-92. PMID 23686264 DOI: 10.1128/Aem.00985-13 |
0.327 |
|
2013 |
Zhao Y, Xiang S, Dai X, Yang K. A simplified diphenylamine colorimetric method for growth quantification. Applied Microbiology and Biotechnology. 97: 5069-77. PMID 23604560 DOI: 10.1007/S00253-013-4893-Y |
0.698 |
|
2012 |
Fan K, Pan G, Peng X, Zheng J, Gao W, Wang J, Wang W, Li Y, Yang K. Identification of JadG as the B ring opening oxygenase catalyzing the oxidative C-C bond cleavage reaction in jadomycin biosynthesis. Chemistry & Biology. 19: 1381-90. PMID 23177193 DOI: 10.1016/J.Chembiol.2012.09.009 |
0.651 |
|
2012 |
Ji J, Fan K, Tian X, Zhang X, Zhang Y, Yang K. Iterative combinatorial mutagenesis as an effective strategy for generation of deacetoxycephalosporin C synthase with improved activity toward penicillin G. Applied and Environmental Microbiology. 78: 7809-12. PMID 22923414 DOI: 10.1128/Aem.02122-12 |
0.304 |
|
2012 |
Patrikainen P, Kallio P, Fan K, Klika KD, Shaaban KA, Mäntsälä P, Rohr J, Yang K, Niemi J, Metsä-Ketelä M. Tailoring enzymes involved in the biosynthesis of angucyclines contain latent context-dependent catalytic activities. Chemistry & Biology. 19: 647-55. PMID 22633416 DOI: 10.1016/J.Chembiol.2012.04.010 |
0.357 |
|
2012 |
Yu T, Xu X, Peng Y, Luo Y, Yang K. Cell wall proteome of Clostridium thermocellum and detection of glycoproteins. Microbiological Research. 167: 364-71. PMID 22494898 DOI: 10.1016/J.Micres.2012.02.006 |
0.324 |
|
2012 |
Yin H, Xiang S, Zheng J, Fan K, Yu T, Yang X, Peng Y, Wang H, Feng D, Luo Y, Bai H, Yang K. Induction of holomycin production and complex metabolic changes by the argR mutation in Streptomyces clavuligerus NP1. Applied and Environmental Microbiology. 78: 3431-41. PMID 22344669 DOI: 10.1128/Aem.07699-11 |
0.376 |
|
2012 |
Ji J, Tian X, Fan K, Yang K. New strategy of site-directed mutagenesis identifies new sites to improve Streptomyces clavuligerus deacetoxycephalosporin C synthase activity toward penicillin G. Applied Microbiology and Biotechnology. 93: 2395-401. PMID 21909691 DOI: 10.1007/S00253-011-3566-Y |
0.314 |
|
2011 |
Wang J, Wang W, Wang L, Zhang G, Fan K, Tan H, Yang K. A novel role of 'pseudo'γ-butyrolactone receptors in controlling γ-butyrolactone biosynthesis in Streptomyces. Molecular Microbiology. 82: 236-50. PMID 21883525 DOI: 10.1111/J.1365-2958.2011.07811.X |
0.339 |
|
2011 |
Ouyang Y, Wu H, Xie L, Wang G, Dai S, Chen M, Yang K, Li X. A method to type the potential angucycline producers in actinomycetes isolated from marine sponges. Antonie Van Leeuwenhoek. 99: 807-15. PMID 21287404 DOI: 10.1007/S10482-011-9554-5 |
0.368 |
|
2011 |
Peng Y, Luo Y, Yu T, Xu X, Fan K, Zhao Y, Yang K. A blue native-PAGE analysis of membrane protein complexes in Clostridium thermocellum. Bmc Microbiology. 11: 22. PMID 21269440 DOI: 10.1186/1471-2180-11-22 |
0.702 |
|
2011 |
Wu X, Tian X, Ji J, Wu W, Fan K, Yang K. Saturation mutagenesis of Acremonium chrysogenum deacetoxy/deacetylcephalosporin C synthase R308 site confirms its role in controlling substrate specificity Biotechnology Letters. 33: 805-812. PMID 21190060 DOI: 10.1007/S10529-010-0504-5 |
0.342 |
|
2010 |
Xu G, Wang J, Wang L, Tian X, Yang H, Fan K, Yang K, Tan H. "Pseudo" gamma-butyrolactone receptors respond to antibiotic signals to coordinate antibiotic biosynthesis. The Journal of Biological Chemistry. 285: 27440-8. PMID 20562102 DOI: 10.1074/Jbc.M110.143081 |
0.31 |
|
2009 |
Xiang SH, Li J, Yin H, Zheng JT, Yang X, Wang HB, Luo JL, Bai H, Yang KQ. Application of a double-reporter-guided mutant selection method to improve clavulanic acid production in Streptomyces clavuligerus. Metabolic Engineering. 11: 310-8. PMID 19584003 DOI: 10.1016/J.Ymben.2009.06.003 |
0.331 |
|
2009 |
Wang L, Tian X, Wang J, Yang H, Fan K, Xu G, Yang K, Tan H. Autoregulation of antibiotic biosynthesis by binding of the end product to an atypical response regulator. Proceedings of the National Academy of Sciences of the United States of America. 106: 8617-22. PMID 19423672 DOI: 10.1073/Pnas.0900592106 |
0.393 |
|
2008 |
Xu X, Wang Z, Fan K, Wang S, Jia C, Han H, Ramalingam E, Yang K. Localization of the ActIII actinorhodin polyketide ketoreductase to the cell wall Fems Microbiology Letters. 287: 15-21. PMID 18691223 DOI: 10.1111/J.1574-6968.2008.01289.X |
0.317 |
|
2008 |
Wang S, Fan K, Yang X, Lin Z, Xu X, Yang K. CabC, an EF-Hand Calcium-Binding Protein, Is Involved in Ca2+-Mediated Regulation of Spore Germination and Aerial Hypha Formation in Streptomyces coelicolor Journal of Bacteriology. 190: 4061-4068. PMID 18375559 DOI: 10.1128/Jb.01954-07 |
0.311 |
|
2007 |
Zheng J, Wang S, Yang K. Engineering a regulatory region of jadomycin gene cluster to improve jadomycin B production in Streptomyces venezuelae Applied Microbiology and Biotechnology. 76: 883-888. PMID 17653711 DOI: 10.1007/S00253-007-1064-Z |
0.407 |
|
2007 |
He Y, Fan K, Jia C, Wang Z, Pan W, Huang L, Yang K, Dong Z. Characterization of a hyperthermostable Fe-superoxide dismutase from hot spring. Applied Microbiology and Biotechnology. 75: 367-376. PMID 17262208 DOI: 10.1007/S00253-006-0834-3 |
0.338 |
|
2005 |
Wu X, Fan K, Wang Q, Yang K. C-terminus mutations of Acremonium chrysogenum deacetoxy/deacetylcephalosporin C synthase with improved activity toward penicillin analogs Fems Microbiology Letters. 246: 103-110. PMID 15869968 DOI: 10.1016/J.Femsle.2005.03.043 |
0.316 |
|
2005 |
Chen YH, Wang CC, Greenwell L, Rix U, Hoffmeister D, Vining LC, Rohr J, Yang KQ. Functional analyses of oxygenases in jadomycin biosynthesis and identification of JadH as a bifunctional oxygenase/dehydrase Journal of Biological Chemistry. 280: 22508-22514. PMID 15817470 DOI: 10.1074/Jbc.M414229200 |
0.682 |
|
2005 |
Rix U, Wang C, Chen Y, Lipata FM, Rix LLR, Greenwell LM, Vining LC, Yang K, Rohr J. The oxidative ring cleavage in jadomycin biosynthesis: A multistep oxygenation cascade in a biosynthetic black box Chembiochem. 6: 838-845. PMID 15776503 DOI: 10.1002/Cbic.200400395 |
0.705 |
|
2004 |
Rix U, Zheng J, Remsing Rix LL, Greenwell L, Yang K, Rohr J. The dynamic structure of jadomycin B and the amino acid incorporation step of its biosynthesis. Journal of the American Chemical Society. 126: 4496-7. PMID 15070349 DOI: 10.1021/Ja031724O |
0.346 |
|
2001 |
Yang K, Han L, He J, Wang L, Vining LC. A repressor-response regulator gene pair controlling jadomycin B production in Streptomyces venezuelae ISP5230 Gene. 279: 165-173. PMID 11733141 DOI: 10.1016/S0378-1119(01)00723-5 |
0.76 |
|
2000 |
Han L, Yang K, Kulowski K, Wendt-Pienkowski E, Hutchinson CR, Vining LC. An acyl-coenzyme A carboxylase encoding gene associated with jadomycin biosynthesis in Streptomyces venezuelae ISP5230 Microbiology. 146: 903-910. PMID 10784049 DOI: 10.1099/00221287-146-4-903 |
0.693 |
|
1999 |
Kulowski K, Wendt-Pienkowski E, Han L, Yang K, Vining LC, Richard Hutchinson C. Functional characterization of the jadI gene as a cyclase forming angucyclinones Journal of the American Chemical Society. 121: 1786-1794. DOI: 10.1021/ja982707f |
0.615 |
|
1997 |
Bateman KP, Thibault P, Yang K, White RL, Vining LC. Probing the substrate specificity of an enzyme catalyzing inactivation of streptogramin B antibiotics using LC-MS and LC-MS/MS. Journal of Mass Spectrometry : Jms. 32: 1057-63. PMID 9358629 DOI: 10.1002/(Sici)1096-9888(199711)32:10<1057::Aid-Jms558>3.0.Co;2-D |
0.63 |
|
1996 |
Facey SJ, Groß F, Vining LC, Yang K, Van Pée KH. Cloning, sequencing and disruption of a bromoperoxidase-catalase gene in Streptomyces venezuelae: Evidence that it is not required for chlorination in chloramphenicol biosynthesis Microbiology. 142: 657-665. PMID 8868441 DOI: 10.1099/13500872-142-3-657 |
0.666 |
|
1996 |
Yang K, Han L, Ayer SW, Vining LC. Accumulation of the angucycline antibiotic rabelomycin after disruption of an oxygenase gene in the jadomycin B biosynthetic gene cluster of Streptomyces venezuelae Microbiology. 142: 123-132. PMID 8581159 DOI: 10.1099/13500872-142-1-123 |
0.691 |
|
1996 |
Bateman KP, Yang K, Thibault P, White RL, Vining LC. Inactivation of etamycin by a novel elimination mechanism in Streptomyces lividans Journal of the American Chemical Society. 118: 5335-5338. DOI: 10.1021/Ja9539103 |
0.644 |
|
1995 |
Mosher RH, Camp DJ, Yang K, Brown MP, Shaw WV, Vining LC. Inactivation of chloramphenicol by O-phosphorylation. A novel resistance mechanism in Streptomyces venezuelae ISP5230, a chloramphenicol producer Journal of Biological Chemistry. 270: 27000-27006. PMID 7592948 DOI: 10.1074/Jbc.270.45.27000 |
0.653 |
|
1994 |
Han L, Yang K, Ramalingam E, Mosher RH, Vining LC. Cloning and characterization of polyketide synthase genes for jadomycin B biosynthesis in Streptomyces venezuelae ISP5230 Microbiology. 140: 3379-3389. PMID 7881555 DOI: 10.1099/13500872-140-12-3379 |
0.679 |
|
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