Lynne Elizabeth Maquat - Publications

Affiliations: 
Biochemistry and Biophysics University of Rochester, Rochester, NY 
Area:
RNA metabolism
Website:
http://www.urmc.rochester.edu/people/23074170-lynne-elizabeth-maquat

159 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kurosaki T, Rambout X, Maquat LE. FMRP-mediated spatial regulation of physiologic NMD targets in neuronal cells. Genome Biology. 25: 31. PMID 38263082 DOI: 10.1186/s13059-023-03146-x  0.496
2022 Kurosaki T, Mitsutomi S, Hewko A, Akimitsu N, Maquat LE. Integrative omics indicate FMRP sequesters mRNA from translation and deadenylation in human neuronal cells. Molecular Cell. PMID 36356584 DOI: 10.1016/j.molcel.2022.10.018  0.827
2022 Cho H, Abshire ET, Popp MW, Pröschel C, Schwartz JL, Yeo GW, Maquat LE. AKT constitutes a signal-promoted alternative exon-junction complex that regulates nonsense-mediated mRNA decay. Molecular Cell. PMID 35675814 DOI: 10.1016/j.molcel.2022.05.013  0.424
2021 Kurosaki T, Sakano H, Pröschel C, Wheeler J, Hewko A, Maquat LE. NMD abnormalities during brain development in the Fmr1-knockout mouse model of fragile X syndrome. Genome Biology. 22: 317. PMID 34784943 DOI: 10.1186/s13059-021-02530-9  0.756
2021 Kurosaki T, Imamachi N, Pröschel C, Mitsutomi S, Nagao R, Akimitsu N, Maquat LE. Loss of the fragile X syndrome protein FMRP results in misregulation of nonsense-mediated mRNA decay. Nature Cell Biology. 23: 40-48. PMID 33420492 DOI: 10.1038/s41556-020-00618-1  0.779
2020 Rambout X, Maquat LE. NCBP3: A Multifaceted Adaptive Regulator of Gene Expression. Trends in Biochemical Sciences. PMID 33032857 DOI: 10.1016/j.tibs.2020.09.003  0.427
2020 Rambout X, Maquat LE. The nuclear cap-binding complex as choreographer of gene transcription and pre-mRNA processing. Genes & Development. 34: 1113-1127. PMID 32873578 DOI: 10.1101/Gad.339986.120  0.525
2020 Zheng D, Cho H, Wang W, Rambout X, Tian B, Maquat LE. 3'READS+RIP defines differential Staufen1 binding to alternative 3'UTR isoforms and reveals structures and sequence motifs influencing binding and polysome association. Rna (New York, N.Y.). PMID 32796083 DOI: 10.1261/Rna.076133.120  0.479
2020 Popp MW, Cho H, Maquat LE. Viral subversion of nonsense-mediated mRNA decay. Rna (New York, N.Y.). PMID 32699064 DOI: 10.1261/Rna.076687.120  0.427
2020 Rambout X, Cho H, Maquat LE. Transcriptional Coactivator PGC-1α Binding to Newly Synthesized RNA via CBP80: A Nexus for Co- and Posttranscriptional Gene Regulation. Cold Spring Harbor Symposia On Quantitative Biology. PMID 32295928 DOI: 10.1101/Sqb.2019.84.040212  0.462
2020 Maquat LE. Short interspersed nuclear element (SINE)-mediated post-transcriptional effects on human and mouse gene expression: SINE-UP for active duty. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 375: 20190344. PMID 32075563 DOI: 10.1098/Rstb.2019.0344  0.58
2019 Wolin SL, Maquat LE. Cellular RNA surveillance in health and disease. Science (New York, N.Y.). 366: 822-827. PMID 31727827 DOI: 10.1126/Science.Aax2957  0.481
2019 Kurosaki T, Popp MW, Maquat LE. Publisher Correction: Quality and quantity control of gene expression by nonsense-mediated mRNA decay. Nature Reviews. Molecular Cell Biology. PMID 31028366 DOI: 10.1038/S41580-019-0138-Y  0.764
2019 Kurosaki T, Popp MW, Maquat LE. Quality and quantity control of gene expression by nonsense-mediated mRNA decay. Nature Reviews. Molecular Cell Biology. PMID 30992545 DOI: 10.1038/S41580-019-0126-2  0.819
2019 Kim YK, Maquat LE. UPFront and center in RNA decay: UPF1 in nonsense-mediated mRNA decay and beyond. Rna (New York, N.Y.). PMID 30655309 DOI: 10.1261/Rna.070136.118  0.654
2018 Kurosaki T, Myers JR, Maquat LE. Defining nonsense-mediated mRNA decay intermediates in human cells. Methods (San Diego, Calif.). PMID 30576707 DOI: 10.1016/J.Ymeth.2018.12.005  0.832
2018 Kurosaki T, Miyoshi K, Myers JR, Maquat LE. Publisher Correction: NMD-degradome sequencing reveals ribosome-bound intermediates with 3'-end non-templated nucleotides. Nature Structural & Molecular Biology. PMID 30353197 DOI: 10.1038/S41594-018-0153-2  0.712
2018 Kurosaki T, Miyoshi K, Myers JR, Maquat LE. NMD-degradome sequencing reveals ribosome-bound intermediates with 3'-end non-templated nucleotides. Nature Structural & Molecular Biology. PMID 30275517 DOI: 10.1038/S41594-018-0132-7  0.832
2018 Elbarbary R, Maquat LE. Evaluating the susceptibility of AGO2-loaded microRNAs to degradation by nucleases in vitro. Methods (San Diego, Calif.). PMID 29777751 DOI: 10.1016/J.Ymeth.2018.05.010  0.309
2018 Walter NG, Maquat LE. Introduction-RNA: From Single Molecules to Medicine. Chemical Reviews. 118: 4117-4119. PMID 29690768 DOI: 10.1021/Acs.Chemrev.8B00095  0.336
2018 Cho H, Rambout X, Gleghorn ML, Nguyen PQT, Phipps CR, Miyoshi K, Myers JR, Kataoka N, Fasan R, Maquat LE. Transcriptional coactivator PGC-1α contains a novel CBP80-binding motif that orchestrates efficient target gene expression. Genes & Development. PMID 29654059 DOI: 10.1101/Gad.309773.117  0.415
2018 Kurosaki T, Maquat LE. Molecular autopsy provides evidence for widespread ribosome-phased mRNA fragmentation. Nature Structural & Molecular Biology. PMID 29555971 DOI: 10.1038/S41594-018-0048-2  0.821
2018 Lucas BA, Lavi E, Shiue L, Cho H, Katzman S, Miyoshi K, Siomi MC, Carmel L, Ares M, Maquat LE. Evidence for convergent evolution of SINE-directed Staufen-mediated mRNA decay. Proceedings of the National Academy of Sciences of the United States of America. PMID 29339519 DOI: 10.1073/Pnas.1715531115  0.461
2018 Kurosaki T, Hoque M, Maquat LE. Identifying Cellular Nonsense-Mediated mRNA Decay (NMD) Targets: Immunoprecipitation of Phosphorylated UPF1 Followed by RNA Sequencing (p-UPF1 RIP-Seq). Methods in Molecular Biology (Clifton, N.J.). 1720: 175-186. PMID 29236259 DOI: 10.1007/978-1-4939-7540-2_13  0.798
2017 Rambout X, Dequiedt F, Maquat LE. Beyond Transcription: Roles of Transcription Factors in Pre-mRNA Splicing. Chemical Reviews. PMID 29251915 DOI: 10.1021/Acs.Chemrev.7B00470  0.582
2017 Popp MW, Maquat LE. Nonsense-mediated mRNA Decay and Cancer. Current Opinion in Genetics & Development. 48: 44-50. PMID 29121514 DOI: 10.1016/J.Gde.2017.10.007  0.489
2017 Elbarbary RA, Miyoshi K, Hedaya O, Myers JR, Maquat LE. UPF1 helicase promotes TSN-mediated miRNA decay. Genes & Development. PMID 28827400 DOI: 10.1101/Gad.303537.117  0.333
2017 Elbarbary RA, Maquat LE. Distinct mechanisms obviate the potentially toxic effects of inverted-repeat Alu elements on cellular RNA metabolism. Nature Structural & Molecular Biology. 24: 496-498. PMID 28586325 DOI: 10.1038/Nsmb.3416  0.45
2017 Elbarbary RA, Miyoshi K, Myers JR, Du P, Ashton JM, Tian B, Maquat LE. Tudor-SN-mediated endonucleolytic decay of human cell microRNAs promotes G1/S phase transition. Science (New York, N.Y.). 356: 859-862. PMID 28546213 DOI: 10.1126/Science.Aai9372  0.341
2016 Popp MW, Maquat LE. Leveraging Rules of Nonsense-Mediated mRNA Decay for Genome Engineering and Personalized Medicine. Cell. 165: 1319-22. PMID 27259145 DOI: 10.1016/J.Cell.2016.05.053  0.513
2016 Elbarbary RA, Maquat LE. Coupling pre-mRNA splicing and 3' end formation to mRNA export: alternative ways to punch the nuclear export clock. Genes & Development. 30: 487-8. PMID 26944675 DOI: 10.1101/Gad.278937.116  0.605
2016 Elbarbary RA, Lucas BA, Maquat LE. Retrotransposons as regulators of gene expression. Science (New York, N.Y.). 351: aac7247. PMID 26912865 DOI: 10.1126/Science.Aac7247  0.41
2016 Maquat LE. Eukaryotic antisense ahead of its time. Nature Reviews. Molecular Cell Biology. PMID 26908010 DOI: 10.1038/Nrm.2016.1  0.345
2016 Kurosaki T, Maquat LE. Nonsense-mediated mRNA decay in humans at a glance. Journal of Cell Science. PMID 26787741 DOI: 10.1242/Jcs.181008  0.836
2015 Elbarbary RA, Maquat LE. CARMing down the SINEs of anarchy: two paths to freedom from paraspeckle detention. Genes & Development. 29: 687-9. PMID 25838539 DOI: 10.1101/Gad.261438.115  0.531
2015 Popp MW, Maquat LE. Attenuation of nonsense-mediated mRNA decay facilitates the response to chemotherapeutics. Nature Communications. 6: 6632. PMID 25808464 DOI: 10.1038/Ncomms7632  0.58
2015 Popp MW, Maquat LE. A TRICK'n way to see the pioneer round of translation: Watching where and when individual messenger RNAs direct protein synthesis in live cells Science. 347: 1316-1317. PMID 25792317 DOI: 10.1126/Science.Aaa9484  0.538
2015 Maquat LE. The amazing web of post-transcriptional gene control: the sum of small changes can make for significant consequences. Rna (New York, N.Y.). 21: 488-9. PMID 25780107 DOI: 10.1261/Rna.049718.115  0.632
2015 Jackson KL, Dayton RD, Orchard EA, Ju S, Ringe D, Petsko GA, Maquat LE, Klein RL. Preservation of forelimb function by UPF1 gene therapy in a rat model of TDP-43-induced motor paralysis. Gene Therapy. 22: 20-8. PMID 25354681 DOI: 10.1038/Gt.2014.101  0.337
2015 Gong C, Maquat LE. Affinity purification of long noncoding RNA–protein complexes from formaldehyde cross-linked mammalian cells Methods in Molecular Biology. 1206: 81-86. PMID 25240888 DOI: 10.1007/978-1-4939-1369-5_7  0.611
2015 Popp MW, Maquat LE. Attenuation of nonsense-mediated mRNA decay facilitates the response to chemotherapeutics Nature Communications. 6. DOI: 10.1038/ncomms7632  0.443
2014 Kurosaki T, Li W, Hoque M, Popp MW, Ermolenko DN, Tian B, Maquat LE. A post-translational regulatory switch on UPF1 controls targeted mRNA degradation. Genes & Development. 28: 1900-16. PMID 25184677 DOI: 10.1101/Gad.245506.114  0.824
2014 Gleghorn ML, Maquat LE. 'Black sheep' that don't leave the double-stranded RNA-binding domain fold Trends in Biochemical Sciences. 39: 328-340. PMID 24954387 DOI: 10.1016/J.Tibs.2014.05.003  0.421
2014 Popp MWL, Maquat LE. Defective secretory-protein mRNAs take the RAPP Trends in Biochemical Sciences. 39: 154-156. PMID 24602384 DOI: 10.1016/J.Tibs.2014.02.001  0.439
2014 Popp MWL, Maquat LE. The dharma of nonsense-mediated mRNA decay in mammalian cells Molecules and Cells. 37: 1-8. PMID 24552703 DOI: 10.14348/Molcells.2014.2193  0.652
2014 Elbarbary RA, Maquat LE. Dodging two bullets with one dsRNA-binding protein Cell Cycle. 13: 345-346. PMID 24335473 DOI: 10.4161/Cc.27512  0.634
2014 Gong C, Tang Y, Maquat LE. Erratum: Corrigendum: mRNA–mRNA duplexes that autoelicit Staufen1-mediated mRNA decay Nature Structural & Molecular Biology. 21: 1106-1106. DOI: 10.1038/Nsmb1214-1106A  0.742
2013 Wei-Lin Popp M, Maquat LE. Organizing principles of Mammalian nonsense-mediated mRNA decay Annual Review of Genetics. 47: 139-165. PMID 24274751 DOI: 10.1146/Annurev-Genet-111212-133424  0.515
2013 Gong C, Tang Y, Maquat LE. MRNA-mRNA duplexes that autoelicit Staufen1-mediated mRNA decay Nature Structural and Molecular Biology. 20: 1214-1222. PMID 24056942 DOI: 10.1038/Nsmb.2664  0.766
2013 Elbarbary RA, Li W, Tian B, Maquat LE. STAU1 binding 3' UTR IRAlus complements nuclear retention to protect cells from PKR-mediated translational shutdown. Genes & Development. 27: 1495-510. PMID 23824540 DOI: 10.1101/Gad.220962.113  0.497
2013 Wang J, Lucas BA, Maquat LE. New gene expression pipelines gush lncRNAs Genome Biology. 117. PMID 23714047 DOI: 10.1186/Gb-2013-14-5-117  0.303
2013 Park E, Maquat LE. Staufen-mediated mRNA decay Wiley Interdisciplinary Reviews: Rna. 4: 423-435. PMID 23681777 DOI: 10.1002/Wrna.1168  0.622
2013 Wang J, Gong C, Maquat LE. Control of myogenesis by rodent SINE-containing lncRNAs Genes and Development. 27: 793-804. PMID 23558772 DOI: 10.1101/Gad.212639.112  0.676
2013 Gleghorn ML, Gong C, Kielkopf CL, Maquat LE. Staufen1 dimerizes through a conserved motif and a degenerate dsRNA-binding domain to promote mRNA decay Nature Structural and Molecular Biology. 20: 515-524. PMID 23524536 DOI: 10.1038/Nsmb.2528  0.682
2013 Trcek T, Sato H, Singer RH, Maquat LE. Temporal and spatial characterization of nonsense-mediated mRNA decay. Genes & Development. 27: 541-51. PMID 23431032 DOI: 10.1101/Gad.209635.112  0.587
2013 Kurosaki T, Maquat LE. Rules that govern UPF1 binding to mRNA 3' UTRs Proceedings of the National Academy of Sciences of the United States of America. 110: 3357-3362. PMID 23404710 DOI: 10.1073/Pnas.1219908110  0.821
2013 Park E, Gleghorn ML, Maquat LE. Staufen2 functions in Staufen1-mediated mRNA decay by binding to itself and its paralog and promoting UPF1 helicase but not ATPase activity Proceedings of the National Academy of Sciences of the United States of America. 110: 405-412. PMID 23263869 DOI: 10.1073/Pnas.1213508110  0.593
2012 Gong C, Popp MWL, Maquat LE. Biochemical analysis of long non-coding RNA-containing ribonucleoprotein complexes Methods. 58: 88-93. PMID 22789663 DOI: 10.1016/J.Ymeth.2012.06.020  0.616
2012 Schoenberg DR, Maquat LE. Regulation of cytoplasmic mRNA decay Nature Reviews Genetics. 13: 246-259. PMID 22392217 DOI: 10.1038/Nrg3160  0.571
2012 Schoenberg DR, Maquat LE. Erratum: Regulation of cytoplasmic mRNA decay Nature Reviews Genetics. 13: 448-448. DOI: 10.1038/Nrg3254  0.401
2011 Hwang J, Maquat LE. Nonsense-mediated mRNA decay (NMD) in animal embryogenesis: To die or not to die, that is the question Current Opinion in Genetics and Development. 21: 422-430. PMID 21550797 DOI: 10.1016/J.Gde.2011.03.008  0.504
2011 Ju S, Tardiff DF, Han H, Divya K, Zhong Q, Maquat LE, Bosco DA, Hayward LJ, Brown RH, Lindquist S, Ringe D, Petsko GA. A yeast model of FUS/TLS-dependent cytotoxicity. Plos Biology. 9: e1001052. PMID 21541368 DOI: 10.1371/Journal.Pbio.1001052  0.451
2011 Gong C, Maquat LE. "Alu"strious long ncRNAs and their role in shortening mRNA half-lives. Cell Cycle (Georgetown, Tex.). 10: 1882-3. PMID 21487233 DOI: 10.4161/Cc.10.12.15589  0.705
2011 Gleghorn ML, Maquat LE. UPF1 learns to relax and unwind. Molecular Cell. 41: 621-3. PMID 21419337 DOI: 10.1016/J.Molcel.2011.03.001  0.434
2011 Gong C, Maquat LE. LncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 39 UTRs via Alu eleme Nature. 470: 284-290. PMID 21307942 DOI: 10.1038/Nature09701  0.734
2011 Gong C, Maquat LE. ALUstrious long ncRNAs and their roles in shortening mRNA half-lives Cell Cycle. 10: 1882-1883. DOI: 10.4161/cc.10.12.15589  0.659
2010 Maquat LE, Hwang J, Sato H, Tang Y. CBP80-promoted mRNP rearrangements during the pioneer round of translation, nonsense-mediated mRNA decay, and thereafter Cold Spring Harbor Symposia On Quantitative Biology. 75: 127-134. PMID 21447822 DOI: 10.1101/Sqb.2010.75.028  0.356
2010 Maquat LE, Tarn WY, Isken O. The pioneer round of translation: Features and functions Cell. 142: 368-374. PMID 20691898 DOI: 10.1016/J.Cell.2010.07.022  0.622
2010 Hwang J, Sato H, Tang Y, Matsuda D, Maquat LE. UPF1 association with the cap-binding protein, CBP80, promotes nonsense-mediated mRNA decay at two distinct steps Molecular Cell. 39: 396-409. PMID 20691628 DOI: 10.1016/J.Molcel.2010.07.004  0.601
2009 Isken O, Maquat LE. Telomeric RNAs as a novel player in telomeric integrity. F1000 Biology Reports. 1: 90. PMID 20376293 DOI: 10.3410/B1-90  0.336
2009 Maquat LE, Gong C. Gene expression networks: Competing mRNA decay pathways in mammalian cells Biochemical Society Transactions. 37: 1287-1292. PMID 19909264 DOI: 10.1042/Bst0371287  0.687
2009 Sato H, Maquat LE. Remodeling of the pioneer translation initiation complex involves translation and the karyopherin importin β Genes and Development. 23: 2537-2550. PMID 19884259 DOI: 10.1101/Gad.1817109  0.629
2009 Schoenberg DR, Maquat LE. Re-capping the message Trends in Biochemical Sciences. 34: 435-442. PMID 19729311 DOI: 10.1016/J.Tibs.2009.05.003  0.604
2009 Gong C, Kim YK, Woeller CF, Tang Y, Maquat LE. SMD and NMD are competitive pathways that contribute to myogenesis: Effects on PAX3 and myogenin mRNAs Genes and Development. 23: 54-66. PMID 19095803 DOI: 10.1101/Gad.1717309  0.731
2008 Matsuda D, Sato H, Maquat LE. Chapter 9 Studying Nonsense-Mediated mRNA Decay in Mammalian Cells Methods in Enzymology. 449: 177-201. PMID 19215759 DOI: 10.1016/S0076-6879(08)02409-9  0.645
2008 Maquat LE, Kiledjian M. RNA turnover in eukaryotes: analysis of specialized and quality control RNA decay pathways. Preface. Methods in Enzymology. 449: xvii-xviii. PMID 19215750 DOI: 10.1016/S0076-6879(08)02422-1  0.597
2008 Maquat LE, Arraiano CM. RNA turnover in prokaryotes, archaea and organelles. Preface. Methods in Enzymology. 447: xxiii-xxiv. PMID 19161834 DOI: 10.1016/S0076-6879(08)02229-5  0.369
2008 Maquat LE, Kiledjian M. RNA turnover in eukaryotes: nucleases, pathways and analysis of mRNA decay. Preface. Methods in Enzymology. 448: xxi-xxii. PMID 19111167 DOI: 10.1016/S0076-6879(08)02631-1  0.622
2008 Isken O, Maquat LE. The multiple lives of NMD factors: Balancing roles in gene and genome regulation Nature Reviews Genetics. 9: 699-712. PMID 18679436 DOI: 10.1038/Nrg2402  0.508
2008 Saltzman AL, Kim YK, Pan Q, Fagnani MM, Maquat LE, Blencowe BJ. Regulation of multiple core spliceosomal proteins by alternative splicing-coupled nonsense-mediated mRNA decay. Molecular and Cellular Biology. 28: 4320-30. PMID 18443041 DOI: 10.1128/Mcb.00361-08  0.525
2008 Isken O, Kim YK, Hosoda N, Mayeur GL, Hershey JW, Maquat LE. Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay. Cell. 133: 314-27. PMID 18423202 DOI: 10.1016/J.Cell.2008.02.030  0.624
2008 Woeller CF, Gaspari M, Isken O, Maquat LE. NMD resulting from encephalomyocarditis virus IRES-directed translation initiation seems to be restricted to CBP80/20-bound mRNA Embo Reports. 9: 446-451. PMID 18369367 DOI: 10.1038/Embor.2008.36  0.639
2008 Sato H, Hosoda N, Maquat LE. Efficiency of the Pioneer Round of Translation Affects the Cellular Site of Nonsense-Mediated mRNA Decay Molecular Cell. 29: 255-262. PMID 18243119 DOI: 10.1016/J.Molcel.2007.12.009  0.605
2007 Matsuda D, Hosoda N, Kim YK, Maquat LE. Failsafe nonsense-mediated mRNA decay does not detectably target eIF4E-bound mRNA Nature Structural and Molecular Biology. 14: 974-979. PMID 17873884 DOI: 10.1038/Nsmb1297  0.654
2007 Isken O, Maquat LE. Quality control of eukaryotic mRNA: Safeguarding cells from abnormal mRNA function Genes and Development. 21: 1833-1856. PMID 17671086 DOI: 10.1101/Gad.1566807  0.609
2007 Kim YK, Furic L, Parisien M, Major F, DesGroseillers L, Maquat LE. Staufen1 regulates diverse classes of mammalian transcripts Embo Journal. 26: 2670-2681. PMID 17510634 DOI: 10.1038/Sj.Emboj.7601712  0.63
2006 Kuzmiak HA, Maquat LE. Applying nonsense-mediated mRNA decay research to the clinic: progress and challenges Trends in Molecular Medicine. 12: 306-316. PMID 16782405 DOI: 10.1016/J.Molmed.2006.05.005  0.516
2006 Hosoda N, Lejeune F, Maquat LE. Evidence that poly(A) binding protein C1 binds nuclear pre-mRNA poly(A) tails Molecular and Cellular Biology. 26: 3085-3097. PMID 16581783 DOI: 10.1128/Mcb.26.8.3085-3097.2006  0.609
2006 Pan Q, Saltzman AL, Kim YK, Misquitta C, Shai O, Maquat LE, Frey BJ, Blencowe BJ. Quantitative microarray profiling provides evidence against widespread coupling of alternative splicing with nonsense-mediated mRNA decay to control gene expression. Genes & Development. 20: 153-8. PMID 16418482 DOI: 10.1101/Gad.1382806  0.545
2005 Hosoda N, Yoon KK, Lejeune F, Maquat LE. CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells Nature Structural and Molecular Biology. 12: 893-901. PMID 16186820 DOI: 10.1038/Nsmb995  0.62
2005 Lejeune F, Maquat LE. Mechanistic links between nonsense-mediated mRNA decay and pre-mRNA splicing in mammalian cells Current Opinion in Cell Biology. 17: 309-315. PMID 15901502 DOI: 10.1016/J.Ceb.2005.03.002  0.645
2005 Maquat LE. Nonsense-mediated mRNA decay in mammals Journal of Cell Science. 118: 1773-1776. PMID 15860725 DOI: 10.1242/Jcs.01701  0.6
2005 Gao Q, Das B, Sherman F, Maquat LE. Cap-binding protein 1-mediated and eukaryotic translation initiation factor 4E-mediated pioneer rounds of translation in yeast Proceedings of the National Academy of Sciences of the United States of America. 102: 4258-4263. PMID 15753296 DOI: 10.1073/Pnas.0500684102  0.637
2005 Kim YK, Furic L, DesGroseillers L, Maquat LE. Mammalian Staufen1 recruits Upf1 to specific mRNA 3′UTRs so as to elicit mRNA decay Cell. 120: 195-208. PMID 15680326 DOI: 10.1016/J.Cell.2004.11.050  0.665
2004 Valencia-Sánchez MA, Maquat LE. An enemy within: Fly reconnaissance deploys an endonuclease to destroy nonsense-containing mRNA Trends in Cell Biology. 14: 594-597. PMID 15519847 DOI: 10.1016/J.Tcb.2004.09.010  0.59
2004 Lejeune F, Ranganathan AC, Maquat LE. eIF4G is required for the pioneer round of translation in mammalian cells Nature Structural and Molecular Biology. 11: 992-1000. PMID 15361857 DOI: 10.1038/Nsmb824  0.554
2004 Brumbaugh KM, Otterness DM, Geisen C, Oliveira V, Brognard J, Li X, Lejeune F, Tibbetts RS, Maquat LE, Abraham RT. The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells Molecular Cell. 14: 585-598. PMID 15175154 DOI: 10.1016/J.Molcel.2004.05.005  0.358
2004 Chiu SY, Lejeune F, Ranganathan AC, Maquat LE. The pioneer translation initiation complex is functionally distinct from but structurally overlaps with the steady-state translation initiation complex. Genes & Development. 18: 745-54. PMID 15059963 DOI: 10.1101/Gad.1170204  0.568
2004 Maquat LE. Nonsense-mediated mRNA decay: Splicing, translation and mRNP dynamics Nature Reviews Molecular Cell Biology. 5: 89-99. PMID 15040442 DOI: 10.1038/Nrm1310  0.629
2004 Lejeune F, Maquat LE. Immunopurification and analysis of protein and RNA components of mRNP in mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 257: 115-124. PMID 14770001 DOI: 10.1385/1-59259-750-5:115  0.397
2004 Maquat LE. Nonsense-mediated mRNA decay: A comparative analysis different species Current Genomics. 5: 175-190. DOI: 10.2174/1389202043349453  0.481
2003 Lejeune F, Li X, Maquat LE. Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities Molecular Cell. 12: 675-687. PMID 14527413 DOI: 10.1016/S1097-2765(03)00349-6  0.6
2003 Arraiano CM, Maquat LE. Post-transcriptional control of gene expression: Effectors of mRNA decay Molecular Microbiology. 49: 267-276. PMID 12823827 DOI: 10.1046/J.1365-2958.2003.03545.X  0.521
2003 Chiu SY, Serin G, Ohara O, Maquat LE. Characterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1. Rna (New York, N.Y.). 9: 77-87. PMID 12554878 DOI: 10.1261/Rna.2137903  0.323
2002 Stevens A, Wang Y, Bremer K, Zhang J, Hoepfner R, Antoniou M, Schoenberg DR, Maquat LE. Beta -Globin mRNA decay in erythroid cells: UG site-preferred endonucleolytic cleavage that is augmented by a premature termination codon. Proceedings of the National Academy of Sciences of the United States of America. 99: 12741-6. PMID 12242335 DOI: 10.1073/Pnas.192442399  0.53
2002 Maquat LE. NASty effects on fibrillin pre-mRNA splicing: Another case of ESE does it, but proposals for translation-dependent splice site choice live on Genes and Development. 16: 1743-1753. PMID 12130534 DOI: 10.1101/Gad.1014502  0.609
2002 Lejeune F, Ishigaki Y, Li X, Maquat LE. The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: Dynamics of mRNP remodeling Embo Journal. 21: 3536-3545. PMID 12093754 DOI: 10.1093/Emboj/Cdf345  0.624
2002 Maquat LE. RNA-protein interactions: Insight into gene function Methods. 26: 93-94. PMID 12054885 DOI: 10.1016/S1046-2023(02)00011-7  0.353
2002 Maquat LE. Skiing toward nonstop mRNA decay Science. 295: 2221-2222. PMID 11910094 DOI: 10.1126/Science.1071285  0.414
2002 Maquat LE. Nonsense-mediated mRNA decay. Current Biology : Cb. 12: R196-7. PMID 11909543  0.515
2002 Sun X, Maquat LE. Nonsense-mediated decay: Assaying for effects on selenoprotein mRNAs Methods in Enzymology. 347: 49-57. PMID 11898438 DOI: 10.1016/S0076-6879(02)47007-3  0.566
2001 Maquat LE, Serin G. Nonsense-mediated mRNA decay: Insights into mechanism from the cellular abundance of human Upf1, Upf2, Upf3, and Upf3X proteins Cold Spring Harbor Symposia On Quantitative Biology. 66: 313-320. PMID 12762033 DOI: 10.1101/Sqb.2001.66.313  0.548
2001 Maquat LE. Evidence that selenium deficiency results in the cytoplasmic decay of GPx1 mRNA dependent on pre-mRNA splicing proteins bound to the mRNA exon-exon junction Biofactors. 14: 37-42. PMID 11568438 DOI: 10.1002/Biof.5520140106  0.638
2001 Ishigaki Y, Li X, Serin G, Maquat LE. Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20 Cell. 106: 607-617. PMID 11551508 DOI: 10.1016/S0092-8674(01)00475-5  0.636
2001 Maquat LE, Li X. Mammalian heat shock p70 and histone H4 transcripts, which derive from naturally intronless genes, are immune to nonsense-mediated decay Rna. 7: 445-456. PMID 11333024 DOI: 10.1017/S1355838201002229  0.589
2001 Denning G, Jamieson L, Maquat LE, Thompson EA, Fields AP. Cloning of a novel phosphatidylinositol kinase-related kinase. Characterization of the human SMG-1 RNA surveillance protein Journal of Biological Chemistry. 276: 22709-22714. PMID 11331269 DOI: 10.1074/Jbc.C100144200  0.309
2001 Sun X, Li X, Moriarty PM, Henics T, LaDuca JP, Maquat LE. Nonsense-mediated decay of mRNA for the selenoprotein phospholipid hydroperoxide glutathione peroxidase is detectable in cultured cells but masked or inhibited in rat tissues Molecular Biology of the Cell. 12: 1009-1017. PMID 11294903 DOI: 10.1091/Mbc.12.4.1009  0.548
2001 Pal M, Ishigaki Y, Nagy E, Maquat LE. Evidence that phosphorylation of human Upf1 protein varies with intracellular location and is mediated by a wortmannin-sensitive and rapamycin-sensitive Pl 3-kinase-related kinase signaling pathway Rna. 7: 5-15. PMID 11214180 DOI: 10.1017/S1355838201000127  0.359
2001 Maquat LE, Carmichael GG. Quality control of mRNA function Cell. 104: 173-176. PMID 11207359 DOI: 10.1016/S0092-8674(01)00202-1  0.488
2001 Maquat LE. The power of point mutations Nature Genetics. 27: 5-6. PMID 11137984 DOI: 10.1038/83759  0.427
2001 Serin G, Gersappe A, Black JD, Aronoff R, Maquat LE. Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4) Molecular and Cellular Biology. 21: 209-223. PMID 11113196 DOI: 10.1128/Mcb.21.1.209-223.2001  0.562
2000 Le Hir H, Izaurralde E, Maquat LE, Moore MJ. The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions Embo Journal. 19: 6860-6869. PMID 11118221 DOI: 10.1093/Emboj/19.24.6860  0.618
2000 Sun X, Moriarty PM, Maquat LE. Nonsense-mediated decay of glutathione peroxidase 1 mRNA in the cytoplasm depends on intron position Embo Journal. 19: 4734-4744. PMID 10970865 DOI: 10.1093/Emboj/19.17.4734  0.583
2000 Le Hir H, Moore MJ, Maquat LE. Pre-mRNA splicing alters mRNP composition: Evidence for stable association of proteins at exon-exon junctions Genes and Development. 14: 1098-1108. PMID 10809668 DOI: 10.1101/Gad.14.9.1098  0.538
2000 Valentin C, Cohen-Solal M, Maquat L, Horányi M, Inselt-Kovács M, Hollán S. Identical germ-line mutations in the triosephosphate isomerase alleles of two brothers are associated with distinct clinical phenotypes. Comptes Rendus De L'Academie Des Sciences. Serie Iii, Sciences De La Vie. 323: 245-50. PMID 10782327 DOI: 10.1016/S0764-4469(00)00128-1  0.377
2000 Sun X, Maquat LE. mRNA surveillance in mammalian cells: The relationship between introns and translation termination Rna. 6: 1-8. PMID 10668793 DOI: 10.1017/S1355838200991660  0.441
1998 Zhang J, Sun X, Qian Y, Laduca JP, Maquat LE. At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA: A possible link between nuclear splicing and cytoplasmic translation Molecular and Cellular Biology. 18: 5272-5283. PMID 9710612 DOI: 10.1128/Mcb.18.9.5272  0.603
1998 Sun X, Perlick HA, Dietz HC, Maquat LE. A mutated human homologue to yeast Upf1 protein has a dominant-negative effect on the decay of nonsense-containing mRNAs in mammalian cells Proceedings of the National Academy of Sciences of the United States of America. 95: 10009-10014. PMID 9707591 DOI: 10.1073/Pnas.95.17.10009  0.631
1998 Zhang J, Sun X, Qian Y, Maquat LE. Intron function in the nonsense-mediated decay of β-globin mRNA: Indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm Rna. 4: 801-815. PMID 9671053 DOI: 10.1017/S1355838298971849  0.607
1998 Nagy E, Maquat LE. A rule for termination-codon position within intron-containing genes: When nonsense affects RNA abundance Trends in Biochemical Sciences. 23: 198-199. PMID 9644970 DOI: 10.1016/S0968-0004(98)01208-0  0.385
1998 Moriarty PM, Reddy CC, Maquat LE. Selenium deficiency reduces the abundance of mRNA for Se-dependent glutathione peroxidase 1 by a UGA-dependent mechanism likely to be nonsense codon-mediated decay of cytoplasmic mRNA Molecular and Cellular Biology. 18: 2932-2939. PMID 9566912 DOI: 10.1128/Mcb.18.5.2932  0.583
1998 Moriarty PM, Maquat LE, Roddy CC. Translation-dependent mechanism for TGA codon-mediated decay of mRNA for Se-GPxl during selenium deficiency Faseb Journal. 12: A1429.  0.486
1997 Zhang J, Maquat LE. Evidence that translation reinitiation abrogates nonsense-mediated mRNA decay in mammalian cells. The Embo Journal. 16: 826-33. PMID 9049311 DOI: 10.1093/Emboj/16.4.826  0.576
1996 Stephenson LS, Maquat LE. Cytoplasmic mRNA for human triosephosphate isomerase is immune to nonsense-mediated decay despite forming polysomes. Biochimie. 78: 1043-7. PMID 9150883 DOI: 10.1016/S0300-9084(97)86728-4  0.571
1996 Maquat LE. Defects in RNA splicing and the consequence of shortened translational reading frames. American Journal of Human Genetics. 59: 279-86. PMID 8755945  0.334
1996 Zhang J, Maquat LE. Evidence that the decay of nucleus-associated nonsense mRNA for human triosephosphate isomerase involves nonsense codon recognition after splicing. Rna (New York, N.Y.). 2: 235-43. PMID 8608447  0.57
1995 Nesic D, Zhang J, Maquat LE. Lack of an effect of the efficiency of RNA 3'-end formation on the efficiency of removal of either the final or the penultimate intron in intact cells. Molecular and Cellular Biology. 15: 488-96. PMID 7799958 DOI: 10.1128/Mcb.15.1.488  0.508
1994 Belgrader P, Maquat LE. Nonsense but not missense mutations can decrease the abundance of nuclear mRNA for the mouse major urinary protein, while both types of mutations can facilitate exon skipping. Molecular and Cellular Biology. 14: 6326-36. PMID 8065364 DOI: 10.1128/Mcb.14.9.6326  0.518
1994 Cheng J, Belgrader P, Zhou X, Maquat LE. Introns are cis effectors of the nonsense-codon-mediated reduction in nuclear mRNA abundance. Molecular and Cellular Biology. 14: 6317-25. PMID 8065363 DOI: 10.1128/Mcb.14.9.6317  0.536
1994 Belgrader P, Cheng J, Zhou X, Stephenson LS, Maquat LE. Mammalian nonsense codons can be cis effectors of nuclear mRNA half-life. Molecular and Cellular Biology. 14: 8219-28. PMID 7969159 DOI: 10.1128/Mcb.14.12.8219  0.611
1994 Nesic D, Maquat LE. Upstream introns influence the efficiency of final intron removal and RNA 3'-end formation. Genes & Development. 8: 363-75. PMID 7906237 DOI: 10.1101/Gad.8.3.363  0.462
1993 Cheng J, Maquat LE. Nonsense codons can reduce the abundance of nuclear mRNA without affecting the abundance of pre-mRNA or the half-life of cytoplasmic mRNA. Molecular and Cellular Biology. 13: 1892-902. PMID 8441420 DOI: 10.1128/Mcb.13.3.1892  0.635
1993 Belgrader P, Cheng J, Maquat LE. Evidence to implicate translation by ribosomes in the mechanism by which nonsense codons reduce the nuclear level of human triosephosphate isomerase mRNA. Proceedings of the National Academy of Sciences of the United States of America. 90: 482-6. PMID 8421679 DOI: 10.1073/Pnas.90.2.482  0.629
1993 Nesic D, Cheng J, Maquat LE. Sequences within the last intron function in RNA 3'-end formation in cultured cells. Molecular and Cellular Biology. 13: 3359-69. PMID 7684497 DOI: 10.1128/Mcb.13.6.3359  0.602
1992 Maquat LE. Nuclear mRNA export. Current Opinion in Cell Biology. 3: 1004-12. PMID 1814360 DOI: 10.1016/0955-0674(91)90121-E  0.551
1992 Lim SK, Sigmund CD, Gross KW, Maquat LE. Nonsense codons in human beta-globin mRNA result in the production of mRNA degradation products. Molecular and Cellular Biology. 12: 1149-61. PMID 1545796 DOI: 10.1128/Mcb.12.3.1149  0.582
1992 Lim SK, Maquat LE. Human beta-globin mRNAs that harbor a nonsense codon are degraded in murine erythroid tissues to intermediates lacking regions of exon I or exons I and II that have a cap-like structure at the 5' termini. The Embo Journal. 11: 3271-8. PMID 1324170 DOI: 10.1002/J.1460-2075.1992.Tb05405.X  0.525
1990 Cheng J, Fogel-Petrovic M, Maquat LE. Translation to near the distal end of the penultimate exon is required for normal levels of spliced triosephosphate isomerase mRNA. Molecular and Cellular Biology. 10: 5215-25. PMID 2398889 DOI: 10.1128/Mcb.10.10.5215  0.618
1990 Cheng J, Mielnicki LM, Pruitt SC, Maquat LE. Nucleotide sequence of murine triosephosphate isomerase cDNA Nucleic Acids Research. 18: 4261. PMID 2377473 DOI: 10.1093/Nar/18.14.4261  0.306
1989 Lim S, Mullins J, Chen C, Gross K, Maquat L. Novel metabolism of several beta zero-thalassemic beta-globin mRNAs in the erythroid tissues of transgenic mice. The Embo Journal. 8: 2613-2619. DOI: 10.1002/J.1460-2075.1989.Tb08401.X  0.451
1988 Daar IO, Maquat LE. Premature translation termination mediates triosephosphate isomerase mRNA degradation. Molecular and Cellular Biology. 8: 802-13. PMID 2832737 DOI: 10.1128/Mcb.8.2.802  0.574
1987 Baumann H, Maquat LE. Localization of DNA sequences involved in dexamethasone-dependent expression of the rat alpha 1-acid glycoprotein gene. Molecular and Cellular Biology. 6: 2551-61. PMID 3023939 DOI: 10.1128/Mcb.6.7.2551  0.347
1985 Maquat LE, Kinniburgh AJ. A beta zero-thalassemic beta-globin RNA that is labile in bone marrow cells is relatively stable in HeLa cells. Nucleic Acids Research. 13: 2855-67. PMID 2582366 DOI: 10.1093/Nar/13.8.2855  0.361
1982 Kinniburgh AJ, Maquat LE, Schedl T, Rachmilewitz E, Ross J. mRNA-deficient beta o-thalassemia results from a single nucleotide deletion. Nucleic Acids Research. 10: 5421-7. PMID 6292840 DOI: 10.1093/Nar/10.18.5421  0.556
1981 Maquat LE, Kinniburgh AJ, Rachmilewitz EA, Ross J. Unstable beta-globin mRNA in mRNA-deficient beta o thalassemia. Cell. 27: 543-53. PMID 6101206 DOI: 10.1016/0092-8674(81)90396-2  0.559
1980 Maquat LE, Kinniburgh AJ, Beach LR, Honig GR, Lazerson J, Ershler WB, Ross J. Processing of human beta-globin mRNA precursor to mRNA is defective in three patients with beta+-thalassemia. Proceedings of the National Academy of Sciences of the United States of America. 77: 4287-91. PMID 6933479 DOI: 10.1073/Pnas.77.7.4287  0.577
1980 Maquat LE, Thornton K, Reznikoff WS. lac Promoter mutations located downstream from the transcription start site. Journal of Molecular Biology. 139: 537-49. PMID 6777500 DOI: 10.1016/0022-2836(80)90145-X  0.579
1980 Maquat LE, Reznikoff WS. lac Promoter mutation Pr115 generates a new transcription initiation point. Journal of Molecular Biology. 139: 551-6. PMID 6160250 DOI: 10.1016/0022-2836(80)90146-1  0.636
1978 Maquat LE, Reznikoff WS. In vitro analysis of the Escherichia coli RNA polymerase interaction with wild-type and mutant lactose promoters. Journal of Molecular Biology. 125: 467-90. PMID 368341 DOI: 10.1016/0022-2836(78)90311-X  0.639
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